Hector R. Wong
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(Suggest an Edit or Addition)Hector R. Wong's Published Works
Published Works
- Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children (2020) (425)
- Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock (2008) (356)
- Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. (1996) (318)
- Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFκB activation (1998) (264)
- Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. (2017) (260)
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (2020) (258)
- A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set (2015) (255)
- Robust classification of bacterial and viral infections via integrated host gene expression diagnostics (2016) (241)
- Time for a Neonatal-Specific Consensus Definition for Sepsis (2014) (219)
- Developing a clinically feasible personalized medicine approach to pediatric septic shock. (2015) (214)
- Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. (2007) (213)
- Pathophysiology and treatment of septic shock in neonates. (2010) (202)
- Identification of pediatric septic shock subclasses based on genome-wide expression profiling (2009) (200)
- Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum* (2009) (199)
- Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children. (2014) (197)
- Epigallocatechin, a Green Tea Polyphenol, Attenuates Myocardial Ischemia Reperfusion Injury in Rats (2004) (183)
- Biomarkers for pediatric sepsis and septic shock (2011) (174)
- Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters (2018) (170)
- The pediatric sepsis biomarker risk model (2012) (169)
- Nuclear factor-κB as a therapeutic target in critical care medicine (2003) (169)
- Salmonella Flagellin-Dependent Proinflammatory Responses Are Localized to the Conserved Amino and Carboxyl Regions of the Protein1 (2001) (159)
- Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality. (2013) (156)
- Stress response decreases NF-kappaB nuclear translocation and increases I-kappaBalpha expression in A549 cells. (1997) (152)
- The stress response and the lung. (1997) (149)
- Zinc supplementation in critically ill patients: a key pharmaconutrient? (2008) (148)
- A community approach to mortality prediction in sepsis via gene expression analysis (2018) (144)
- Epigallocatechin-3-gallate, a Green Tea–Derived Polyphenol, Inhibits IL-1β-Dependent Proinflammatory Signal Transduction in Cultured Respiratory Epithelial Cells (2004) (141)
- Combining functional and tubular damage biomarkers improves diagnostic precision for acute kidney injury after cardiac surgery. (2014) (141)
- Extracellular Heat Shock Protein-70 Induces Endotoxin Tolerance in THP-1 Cells1 (2006) (141)
- ADMISSION ANGIOPOIETIN LEVELS IN CHILDREN WITH SEPTIC SHOCK (2007) (137)
- Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4 (2009) (135)
- Interactions between the heat shock response and the nuclear factor-kappaB signaling pathway. (2002) (135)
- Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome. (1995) (129)
- Role of Biomarkers in Sepsis Care (2013) (127)
- Interleukin-8 as a stratification tool for interventional trials involving pediatric septic shock. (2008) (127)
- Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment (2014) (126)
- Absence of inducible nitric oxide synthase modulates early reperfusion‐induced NF‐κB and AP‐1 activation and enhances myocardial damage (2002) (125)
- Prognostic and predictive enrichment in sepsis (2019) (123)
- The Influence of Developmental Age on the Early Transcriptomic Response of Children with Septic Shock (2011) (122)
- Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C (2006) (121)
- Validation of a gene expression-based subclassification strategy for pediatric septic shock* (2011) (120)
- Genome-Level Longitudinal Expression of Signaling Pathways and Gene Networks in Pediatric Septic Shock (2007) (120)
- Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children. (2014) (118)
- The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock. (2011) (117)
- The Heat Shock Response Inhibits Inducible Nitric Oxide Synthase Gene Expression by Blocking Iκ-B Degradation and NF-κB Nuclear Translocation (1997) (116)
- A Green Tea-Derived Polyphenol, Epigallocatechin-3-Gallate, Inhibits IκB Kinase Activation and IL-8 Gene Expression in Respiratory Epithelium (2004) (115)
- INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS (2008) (115)
- Hsp72 Induces Inflammation and Regulates Cytokine Production in Airway Epithelium through a TLR4- and NF-κB-Dependent Mechanism1 (2007) (115)
- Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents. (2002) (113)
- Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans. (1996) (113)
- Gene expression profiling in sepsis: timing, tissue, and translational considerations. (2014) (103)
- Biomarker discovery and development in pediatric critical care medicine* (2011) (100)
- Glutamine's protection against cellular injury is dependent on heat shock factor-1. (2006) (97)
- Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids* (2016) (96)
- A Multibiomarker-Based Outcome Risk Stratification Model for Adult Septic Shock* (2014) (95)
- The A2A receptor mediates an endogenous regulatory pathway of cytokine expression in THP‐1 cells (2002) (95)
- Validating the genomic signature of pediatric septic shock. (2008) (95)
- Heat shock response and acute lung injury. (2007) (94)
- The heat-shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells. (1996) (92)
- AGE-DEPENDENT RESPONSES TO HEPATIC ISCHEMIA/REPERFUSION INJURY (2005) (90)
- Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis. (2008) (90)
- An update and review of acute kidney injury in pediatrics (2011) (89)
- Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children (2012) (85)
- HSP induction inhibits iNOS mRNA expression and attenuates hypotension in endotoxin-challenged rats. (1996) (83)
- Extracellular hsp70 levels in children with septic shock* (2005) (81)
- Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia. (2007) (81)
- Sesquiterpene lactones inhibit inducible nitric oxide synthase gene expression in cultured rat aortic smooth muscle cells. (1999) (80)
- A novel role for matrix metalloproteinase-8 in sepsis* (2012) (80)
- Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1. (2004) (78)
- Curcumin, a medicinal herbal compound capable of inducing the heat shock response (2001) (78)
- Increased expression of heat shock protein-70 protects A549 cells against hyperoxia. (1998) (77)
- Genetics and genomics in pediatric septic shock (2012) (76)
- Absence of endogenous interleukin 10 enhances early stress response during post-ischaemic injury in mice intestine (2001) (76)
- CONTRIBUTION OF MKP-1 REGULATION OF p38 TO ENDOTOXIN TOLERANCE (2005) (76)
- Zinc homeostasis in pediatric critical illness* (2009) (74)
- Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18 (2016) (73)
- Inhaled nitric oxide increases endothelin-1 levels: A potential cause of rebound pulmonary hypertension (2002) (73)
- Mechanisms and Regulation of the Gene-Expression Response to Sepsis (2010) (72)
- Toward a clinically feasible gene expression-based subclassification strategy for septic shock: Proof of concept (2010) (71)
- Testing the Prognostic Accuracy of the Updated Pediatric Sepsis Biomarker Risk Model (2014) (71)
- Clinical review: Sepsis and septic shock - the potential of gene arrays (2012) (71)
- Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice. (2000) (70)
- Pediatric critical care medicine : basic science and clinical evidence (2007) (69)
- Heat Shock Inhibits TNF-Induced ICAM-1 Expression in Human Endothelial Cells Via I Kappa Kinase Inhibition (2002) (68)
- Leukocyte subset-derived genomewide expression profiles in pediatric septic shock* (2009) (67)
- Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice. (2007) (66)
- Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells. (2002) (66)
- Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27. (2007) (66)
- Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium. (2000) (66)
- Theaflavin, a black tea extract, is a novel anti-inflammatory compound (2004) (65)
- Reduced Peroxisome Proliferator-Activated Receptor &agr; Expression Is Associated With Decreased Survival and Increased Tissue Bacterial Load in Sepsis (2012) (65)
- Heat shock activates the I-kappaBalpha promoter and increases I-kappaBalpha mRNA expression. (1999) (64)
- Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype (2016) (64)
- Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock* (2020) (62)
- Sesquiterpene Lactone Parthenolide, an Inhibitor of I&kgr;B Kinase Complex and Nuclear Factor-&kgr;B, Exerts Beneficial Effects in Myocardial Reperfusion Injury (2002) (62)
- Heat shock inhibits phosphorylation of I-κBα (2000) (62)
- DIVERSE CARDIOPROTECTIVE SIGNALING MECHANISMS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ LIGANDS, 15-DEOXY-Δ12,14-PROSTAGLANDIN J2 AND CIGLITAZONE, IN REPERFUSION INJURY: ROLE OF NUCLEAR FACTOR-κB, HEAT SHOCK FACTOR 1, AND AKT (2007) (62)
- Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock (2017) (62)
- Nitric oxide production in critically ill patients. (1996) (61)
- Post-ICU Admission Fluid Balance and Pediatric Septic Shock Outcomes: A Risk-Stratified Analysis* (2014) (61)
- Activation of hepatocytes by extracellular heat shock protein 72. (2008) (61)
- Nuclear factor-kappaB as a therapeutic target in critical care medicine. (2003) (60)
- Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. (1997) (58)
- Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. (2014) (58)
- Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response. (2009) (57)
- Pediatric Sepsis - Part I: "Children are not small adults!" (2011) (57)
- Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway. (2006) (57)
- Corticosteroids and Pediatric Septic Shock Outcomes: A Risk Stratified Analysis (2014) (57)
- HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest. (2008) (56)
- Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells. (2004) (56)
- Expression of iNOS in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response. (1995) (55)
- Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray (2011) (55)
- Intracellular delivery of HSP70 using HIV-1 Tat protein transduction domain. (2003) (55)
- The heat shock response inhibits RANTES gene expression in cultured human lung epithelium. (1998) (54)
- Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis (2012) (54)
- Genome-wide expression profiling in pediatric septic shock (2013) (52)
- Redefining critical illness (2022) (52)
- Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis (2015) (51)
- Cytokine-induced nitric oxide synthase gene transcription is blocked by the heat shock response in human liver cells. (1996) (51)
- Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE‐XP (2017) (49)
- Potential protective role of the heat shock response in sepsis. (1998) (49)
- Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock* (2018) (49)
- Interleukin 27 as a Sepsis Diagnostic Biomarker in Critically Ill Adults (2013) (49)
- Heat shock-mediated regulation of MKP-1. (2005) (48)
- Hyperoxia synergistically increases TNF-α-induced interleukin-8 gene expression in A549 cells (2000) (47)
- Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis* (2003) (47)
- Sepsis Subclasses: A Framework for Development and Interpretation. (2021) (45)
- Transcriptional regulation of iNOS by IL-1 beta in cultured rat pulmonary artery smooth muscle cells. (1996) (45)
- Heat Shock Inhibits Activation of NF-κB in the Absence of Heat Shock Factor-1 (2002) (44)
- Pediatric Sepsis - Part V: Extracellular Heat Shock Proteins: Alarmins for the Host Immune System. (2011) (44)
- Interactions between the heat shock response and the nuclear factor-&kgr;B signaling pathway (2002) (43)
- A Survey of Stated Physician Practices and Beliefs on the Use of Steroids in Pediatric Fluid and/or Vasoactive Infusion-Dependent Shock* (2013) (43)
- Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium. (2001) (43)
- THE GREEN TEA POLYPHENOL EPIGALLOCATECHIN-3-GALLATE IMPROVES SYSTEMIC HEMODYNAMICS AND SURVIVAL IN RODENT MODELS OF POLYMICROBIAL SEPSIS (2007) (42)
- Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model (2019) (42)
- Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock* (2020) (42)
- Plasmapheresis to Treat Hypertriglyceridemia in a Child With Diabetic Ketoacidosis and Pancreatitis (2012) (41)
- Pediatric sepsis: challenges and adjunctive therapies. (2013) (39)
- Changes in peroxisome proliferator-activated receptor-gamma activity in children with septic shock (2009) (39)
- Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children (2020) (39)
- Proteasome Inhibitors Induce Inhibitory κB (IκB) Kinase Activation, IκBα Degradation, and Nuclear Factor κB Activation in HT-29 Cells (2004) (39)
- Interleukin-27: a novel biomarker in predicting bacterial infection among the critically ill (2015) (38)
- Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass (2008) (38)
- German cockroach proteases regulate matrix metalloproteinase‐9 in human bronchial epithelial cells (2006) (38)
- The Temporal Version of the Pediatric Sepsis Biomarker Risk Model (2014) (38)
- DIFFERENTIAL EFFECTS OF HYPEROXIA ON THE INDUCIBLE AND CONSTITUTIVE ISOFORMS OF NITRIC OXIDE SYNTHASE IN THE LUNG (1997) (38)
- Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response (2017) (37)
- Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock* (2010) (37)
- Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals* (2018) (37)
- The heat shock response inhibits inducible nitric oxide synthase gene expression by blocking I kappa-B degradation and NF-kappa B nuclear translocation. (1997) (37)
- Age‐related decrease in proteasome expression contributes to defective nuclear factor‐κB activation during hepatic ischemia/reperfusion (2009) (37)
- Advancing precision medicine for acute respiratory distress syndrome (2021) (36)
- Induction of the stress response increases interleukin-6 production in the intestinal mucosa of endotoxaemic mice. (2000) (36)
- T cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis. (2020) (35)
- PP2A REGULATES UPSTREAM MEMBERS OF THE C-JUN N-TERMINAL KINASE MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING PATHWAY (2007) (35)
- A Cohort Study of Pediatric Shock: Frequency of Corticosteriod Use and Association with Clinical Outcomes (2015) (35)
- Risk Stratification and Prognosis in Sepsis: What Have We Learned from Microarrays? (2016) (35)
- PERSEVERE Biomarkers Predict Severe Acute Kidney Injury and Renal Recovery in Pediatric Septic Shock. (2020) (34)
- Intensive care medicine in 2050: precision medicine (2017) (34)
- A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study* (2017) (34)
- Two subphenotypes of septic acute kidney injury are associated with different 90-day mortality and renal recovery (2020) (34)
- Validation of the Sepsis MetaScore for Diagnosis of Neonatal Sepsis (2018) (33)
- Heat shock activates the I-κBα promoter and increases I-κBα mRNA expression (1999) (33)
- Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock (2007) (32)
- Selective and transient in vitro effects of heat shock on alveolar type II cell gene expression. (1997) (31)
- The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology (2014) (31)
- Admission chemokine (C-C motif) ligand 4 levels predict survival in pediatric septic shock* (2010) (30)
- Emerging infection and sepsis biomarkers: will they change current therapies? (2016) (30)
- A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury (2015) (30)
- Adaptation of a Biomarker-Based Sepsis Mortality Risk Stratification Tool for Pediatric Acute Respiratory Distress Syndrome* (2018) (30)
- CpG DNA modulates interleukin 1β-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells (2006) (30)
- Pediatric Sepsis Endotypes Among Adults With Sepsis (2017) (29)
- Zinc supplementation leads to immune modulation and improved survival in a juvenile model of murine sepsis (2017) (29)
- Heat shock inhibits phosphorylation of I-kappaBalpha. (2000) (29)
- Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (2020) (28)
- Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults. (2014) (28)
- Multicohort Analysis of Whole-Blood Gene Expression Data Does Not Form a Robust Diagnostic for Acute Respiratory Distress Syndrome (2018) (28)
- Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission (2021) (28)
- Temporal and Mechanistic Effects of Heat Shock on LPS-Mediated Degradation of IκBα in Macrophages (2002) (28)
- Clinical Utility of Computed Tomography and Magnetic Resonance Imaging for Diagnosis of Posterior Reversible Encephalopathy Syndrome after Stem Cell Transplantation in Children and Adolescents. (2015) (27)
- SOCS1 is a negative regulator of metabolic reprogramming during sepsis. (2017) (26)
- The Stress Response Decreases NF-&kgr;B Activation in Liver of Endotoxemic Mice (2002) (26)
- PPAR α contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis (2019) (26)
- Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages. (1996) (25)
- Early Diagnosis of Sepsis: Is an Integrated Omics Approach the Way Forward? (2017) (25)
- Histological chorioamnionitis shapes the neonatal transcriptomic immune response. (2016) (25)
- Olfactomedin 4 marks a subset of neutrophils in mice (2018) (25)
- Hypothermia decreases excitatory neurotransmitter release in bacterial meningitis in rabbits 1 Published on the World Wide Web on 1 October 1999. 1 (1999) (25)
- Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor &ggr;* (2009) (25)
- Sepsis in the Pediatric Cardiac Intensive Care Unit (2011) (24)
- Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock (2014) (23)
- Safety and Dose Escalation Study of Intravenous Zinc Supplementation in Pediatric Critical Illness. (2016) (23)
- SODIUM ARSENITE INDUCES THE STRESS RESPONSE IN THE GUT AND DECREASES BACTERIAL TRANSLOCATION IN A BURNED MOUSE MODEL WITH GUT‐DERIVED SEPSIS (2000) (23)
- Nitric oxide decreases surfactant protein A gene expression in H441 cells. (1998) (23)
- Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases. (2017) (23)
- Plasma bactericidal/permeability‐increasing protein concentrations in critically ill children with the sepsis syndrome (1995) (23)
- Precision medicine in pediatric sepsis. (2019) (22)
- Metabolic alkalosis in children undergoing cardiac surgery (1993) (21)
- Heat shock proteins. Facts, thoughts, and dreams (1999) (21)
- Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation (2004) (20)
- Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide (2008) (20)
- Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1. (2002) (20)
- ABLATION OF THE HEAT SHOCK FACTOR-1 INCREASES SUSCEPTIBILITY TO HYPEROXIA-MEDIATED CELLULAR INJURY (2002) (20)
- THE ROLE OF ENDOGENOUSLY PRODUCED EXTRACELLULAR HSP72 IN MONONUCLEAR CELL REPROGRAMMING (2008) (20)
- A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis (2016) (19)
- Molecular genetics in the pediatric intensive care unit. (2003) (19)
- Corticosteroids in Pediatric Shock: A Call to Arms* (2015) (18)
- Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review* (2017) (18)
- Induction of the stress response with prostaglandin A1 increases I-kappaBalpha gene expression. (1998) (18)
- Pediatric septic shock treatment: new clues from genomic profiling. (2007) (18)
- Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats. (2002) (18)
- The Immunomodulatory Effects of Albumin In Vitro and In Vivo (2011) (18)
- Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation. (2020) (18)
- Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis* (2015) (18)
- Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells. (2004) (17)
- A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement (2021) (17)
- Induction of lipopolysaccharide-binding protein gene expression in cultured rat pulmonary artery smooth muscle cells by interleukin 1 beta. (1995) (17)
- Stress response decreases the interleukin-1beta-induced production of complement component C3 in human intestinal epithelial cells. (1999) (17)
- Simplification of a Septic Shock Endotyping Strategy for Clinical Application (2017) (17)
- Intracatheter nitroglycerin infusion fails to prevent catheter-related venous thrombosis: a randomized, controlled trial (2001) (16)
- The glucocorticoid receptor and cortisol levels in pediatric septic shock (2018) (16)
- Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells. (2006) (16)
- The Respiratory Tract in Pediatric Critical Illness and Injury (2009) (16)
- Role of matrix metalloproteinase‐8 as a mediator of injury in intestinal ischemia and reperfusion (2016) (16)
- Improved outcome for young children with AIDS, Pneumocystis carinii pneumonia, and acute respiratory failure (1994) (15)
- Molecular Biology of Acute Lung Injury (2001) (15)
- Intensivist-Led Team Approach to Critical Care of Children With Heart Disease (2006) (15)
- Comparison of Consent Models in a Randomized Trial of Corticosteroids in Pediatric Septic Shock* (2017) (15)
- Short-term modulation of interleukin-1β signaling by hyperoxia: uncoupling of IκB kinase activation and NF-κB-dependent gene expression (2004) (15)
- Cardiac Troponin Measurement in the Critically Ill: Potential for Guiding Clinical Management (2015) (14)
- Combined Zinc Supplementation With Proinsulin C-Peptide Treatment Decreases the Inflammatory Response and Mortality in Murine Polymicrobial Sepsis (2014) (14)
- Monitoring Severity of Multiple Organ Dysfunction Syndrome: New Technologies (2017) (14)
- The Pediatric Sepsis Biomarker Risk Model (PERSEVERE) Biomarkers Predict Clinical Deterioration and Mortality in Immunocompromised Children Evaluated for Infection (2019) (14)
- Evidence of Endotypes in Pediatric Acute Hypoxemic Respiratory Failure Caused by Sepsis* (2019) (14)
- Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome (2020) (14)
- Loss of matrix metalloproteinase-8 is associated with worsened recovery after ischemic kidney injury (2015) (14)
- Hyperoxia synergistically increases TNF-alpha-induced interleukin-8 gene expression in A549 cells. (2000) (14)
- Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile sepsis Model (2016) (13)
- External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients (2020) (13)
- Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock* (2017) (13)
- Juvenile OLFM4 Null Mice Are Protected from Sepsis. (2020) (13)
- Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock (2018) (13)
- Mast cell activation is differentially affected by heat shock. (2005) (13)
- Antecedent acute kidney injury worsens subsequent endotoxin-induced lung inflammation in a two-hit mouse model. (2011) (13)
- Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology (2015) (12)
- High Frequency of Neuroimaging Abnormalities Among Pediatric Patients With Sepsis Who Undergo Neuroimaging* (2017) (12)
- Severe acute kidney injury is independently associated with mortality in children with septic shock (2020) (12)
- Phosphatase inhibition leads to activation of IκB kinase in murine macrophages (2002) (12)
- Increased expression of heat shock protein-70 protects A549 cells against hyperoxia. (1998) (12)
- Resuscitation and stabilization of the critically ill child (2009) (12)
- An International Survey of Corticosteroid Use for the Management of Low Cardiac Output Syndrome* (2017) (12)
- Biological activity of truncated C-terminus human heat shock protein 72. (2011) (12)
- The impact of molecular biology on the practice of pediatric critical care medicine. (2001) (12)
- Mechanism and function of heat shock-dependent IκBα expression (2006) (12)
- Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis (2018) (12)
- ARDS. The future. (2002) (11)
- Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of congenital Diaphragmatic Hernia (2016) (11)
- Hyperoxia prolongs tumor necrosis factor-alpha-mediated activation of NF-kappaB: role of IkappaB kinase. (2002) (11)
- Science and practice of pediatric critical care medicine (2009) (11)
- The PICU perspective on monitoring hemodynamics and oxygen transport. (2011) (11)
- Recalibration of the Renal Angina Index for Pediatric Septic Shock (2021) (11)
- The relative resistance of children to sepsis mortality: from pathways to drug candidates (2018) (11)
- Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid. (2007) (11)
- Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial (2016) (11)
- Glucocorticoid Receptor Expression in Peripheral WBCs of Critically Ill Children* (2015) (11)
- Sepsis in Pediatric Cardiac Intensive Care (2016) (10)
- Comparing the prognostic performance of ASSIST to interleukin-6 and procalcitonin in patients with severe sepsis or septic shock (2015) (10)
- Biomarker Panels in Critical Care (2020) (10)
- Signal Transduction Pathways in Acute Lung Injury: Nf-κB and Ap-1 (2001) (10)
- Pathophysiology of Neonatal Sepsis (2016) (10)
- Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients (2018) (10)
- The United States critical illness and injury trials group: an introduction. (2009) (10)
- Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis (2008) (9)
- Sepsis Biomarkers (2019) (9)
- Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages. (2002) (9)
- The olfactomedin‐4 positive neutrophil has a role in murine intestinal ischemia/reperfusion injury (2019) (9)
- IFN-γ Signature in the Plasma Proteome Distinguishes Pediatric Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS. (2021) (9)
- Pediatric sepsis biomarkers for prognostic and predictive enrichment (2021) (8)
- Differential expression of the Nrf2-linked genes in pediatric septic shock (2015) (8)
- An Enrichment Strategy For Sepsis Clinical Trials (2016) (7)
- Mechanism and function of heat shock-dependent IkappaBalpha expression. (2006) (7)
- A Precision Medicine Approach to Biomarker Utilization in Pediatric Sepsis-Associated Acute Kidney Injury (2021) (7)
- Mortality prediction in sepsis via gene expression analysis: a community approach (2016) (7)
- Proprotein Convertase Subtilisin/Kexin Type 9 Loss-of-Function Is Detrimental to the Juvenile Host With Septic Shock* (2020) (7)
- Nuclear factor-kappa B and nitric oxide regulating life and death: nonsense or harsh reality? (1998) (7)
- Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought. (2014) (7)
- The central nervous system in pediatric critical illness and injury (2009) (7)
- HDL Cholesterol: A “Pathogen Lipid Sink” for Sepsis? (2019) (7)
- A Neutrophil Subset Defined by Intracellular Olfactomedin 4 is Associated with Mortality in Sepsis. (2020) (7)
- Comprar Pediatric Critical Care Medicine · Basic Science and Clinical Evidence | Wheeler, Derek S. | 9781846284632 | Springer (2007) (7)
- Decompressive Abdominal Laparotomy for Abdominal Compartment Syndrome in an Unengrafted Bone Marrow Recipient with Septic Shock (2010) (6)
- Myocardial Dysfunction Is Independently Associated With Mortality in Pediatric Septic Shock (2020) (6)
- Finding new therapies for sepsis: the need for patient stratification and the use of genetic biomarkers (2011) (6)
- Precision medicine in pediatric sepsis. (2019) (6)
- Biomarkers to estimate the probability of complicated appendicitis. (2017) (6)
- Characterization of the Glucocorticoid Receptor in Children Undergoing Cardiac Surgery* (2018) (6)
- Olfactomedin 4 – Positive Neutrophils Are Upregulated after Hemorrhagic Shock (2021) (6)
- Phase 1 safety and pharmacokinetic study on the use of pioglitazone in critically ill patients with sepsis: a randomized clinical trial (2018) (6)
- Personalized medicine, endotypes, and intensive care medicine (2015) (6)
- Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study (2022) (6)
- Protective effects of isohelenin, an inhibitor of nuclear factor κB, in endotoxic shock in rats (2002) (5)
- Respiratory, cardiovascular and central nervous systems (2014) (5)
- Short-term modulation of interleukin-1beta signaling by hyperoxia: uncoupling of IkappaB kinase activation and NF-kappaB-dependent gene expression. (2004) (5)
- Endogenous Cytoprotective Mechanisms (2009) (5)
- Role of gene polymorphisms in sepsis. (2002) (5)
- Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity. (2017) (5)
- Estimating the probability of bacterial infection using a novel biomarker among pediatric patients in the emergency department (2016) (5)
- Cardiovascular pediatric critical illness and injury (2015) (4)
- The Heat Shock Response and Heat Shock Protein 70: Cytoprotection in Acute Lung Injury (2001) (4)
- The Heat Shock Response and Transplantation Immunology (2004) (4)
- Innovation in Pediatric Cardiac Intensive Care (2015) (4)
- Effect of tyrosine kinase inhibition on sepsis-induced vascular hyporesponsiveness, inos mrna expression and NF-kappaB nuclear translocation in rats. (2000) (4)
- HYPEROXIA PROLONGS TUMOR NECROSIS FACTOR- -MEDIATED ACTIVATION OF NF- B: ROLE OF I B KINASE (2002) (4)
- Yet another potential role for nitric oxide in the pathophysiology of septic shock. (2002) (4)
- Longitudinal characterization of olfactomedin-4 expressing neutrophils in pediatric patients undergoing bone marrow transplantation (2020) (4)
- Pediatric critical care (2003) (3)
- Genetic approach to pediatric septic shock. (2008) (3)
- Heat shock proteins. Facts, thoughts, and dreams. A. De Maio. Shock 11:1-12, 1999. (1999) (3)
- Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 Hours post ICU admission (2020) (3)
- Olfactomedin 4 Positive Neutrophils are Upregulated Following Hemorrhagic Shock. (2020) (3)
- Pediatric Sepsis Biomarker Risk Model Biomarkers and Estimation of Myocardial Dysfunction in Pediatric Septic Shock. (2021) (3)
- Route of Oseltamivir Administration Affects Metabolite Concentrations in Critically Ill Children. (2019) (3)
- Genetic association research: understanding its challenges and limitations. (2010) (3)
- Biomarkers Associated with Mortality in Pediatric Patients with Cardiac Arrest and Acute Respiratory Distress Syndrome. (2021) (3)
- Pediatric critical care medicine: Volume 1: Care of the critically ill or injured child, second edition (2014) (3)
- DIETHYLDITHIOCARBAMATE IS A NOVEL PHARMACOLOGIC INDUCER OF HEAT SHOCK PROTEINS IN VITRO (1999) (3)
- Estimating Mortality Risk of Pediatric Critical Illness: A Worthy Obsession. (2016) (3)
- The Role of Extracellular Heat Shock Proteins in Cellular Inflammation and Injury (2006) (3)
- Pediatric Critical Care Medicine (2014) (2)
- SERUM NITRITE AND NITRATE LEVELS IN CRITICALLY ILL CHILDREN (1995) (2)
- INTERLEUKIN-1 beta DECREASES HEAT SHOCK PROTEIN-70 EXPRESSION IN CULTURED HUMAN RESPIRATORY EPITHELIUM (1999) (2)
- CT Scan Frequently Misses the Diagnosis of Posterior Reversible Encephalopathy Syndrome (PRES) after Stem Cell Transplant (2015) (2)
- Chapter 103 – Sepsis (2011) (2)
- EPIGALLOCATECHIN‐3‐GALLATE (EGCG), A GREEN TEA‐DERIVED POLYPHENOL, ATTENUATES CARDIAC INJURY IN A RAT MODEL OF MYOCARDIAL ISCHEMIA‐REPERFUSION INJURY.: 169 (2004) (2)
- Pediatric critical care medicine: Volume 3: Gastroenterological, Endocrine, Renal, Hematologic, Oncologic and Immune Systems (2014) (2)
- Critically associating. (2009) (2)
- Chapter 96 – Sepsis (2006) (2)
- Phosphatase inhibition leads to activation of IkappaB kinase in murine macrophages. (2002) (2)
- THE HEAT SHOCK RESPONSE INHIBITS RANTES GENE EXPRESSION (1998) (2)
- Sepsis genomics and precision medicine (2019) (2)
- EXTRACELLULAR HSP70 AND CELLULAR REPROGRAMMING: 67 (2004) (2)
- Metabolomic Profiling Of Serum Samples By 1H NMR Spectroscopy As A Novel Approach For Diagnosis Of Pediatric Septic Shock (2012) (2)
- Sepsis Subclasses: Be Careful of What You Wish for. (2017) (2)
- Plasma IL-8 As A Risk Stratification Tool For Adults With Septic Shock (2010) (2)
- Matrix Metalloproteinase-8 as a Biomarker of Complicated Appendicitis (2015) (1)
- A community approach to mortality prediction in sepsis via gene expression analysis (2018) (1)
- SERUM HSP70 LEVELS IN CHILDREN WITH SEPSIS: 472 (2002) (1)
- Novel Therapeutic Agents in Pediatric Sepsis - Zinc (2011) (1)
- poor outcome shock indicate a role for altered zinc homeostasis in Genome-level expression profiles in pediatric septic (2015) (1)
- SESQUITERPENE LACTONES INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE GENE EXPRESSION IN RAT AORTIC SMOOTH MUSCLE CELLS (1999) (1)
- 8: NATURAL HISTORY OF CONTEMPORARY PEDIATRIC SEPTIC SHOCK RESULTS FROM THE LAPSE INVESTIGATION (2018) (1)
- “ Children are not Small Adults ! ” (2011) (1)
- 1439: PERSEVERE-II PREDICTS ACUTE KIDNEY INJURY AND RENAL RECOVERY IN CHILDREN WITH SEPTIC SHOCK (2020) (1)
- Matrix metalloproteinases and their inhibitors in pediatric severe acute pancreatitis (2022) (1)
- ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE ENHANCES MYOCARDIAL DAMAGE DURING EARLY REPERFUSION (1999) (1)
- Circulatory Failure/Shock (2021) (1)
- Protein the Conserved Amino and Carboxyl Regions Proinflammatory Responses Are Localized to Flagellin-Dependent Salmonella (2001) (1)
- Electrolyte derangements in critically ill children receiving balanced versus unbalanced crystalloid fluid resuscitation (2022) (1)
- The extracellular stress response to pediatric cardiopulmonary bypass (2014) (1)
- Biomarkers estimating baseline mortality risk for neonatal sepsis: nPERSEVERE: neonate-specific sepsis biomarker risk model. (2022) (1)
- CHAPTER 18 – Genetic Basis of Acute Lung Injury (2008) (1)
- 463. Random Sampling of Asymptomatic Hospital Employees: A Period Prevalence Study (2020) (1)
- 1566: MYOCARDIAL DYSFUNCTION IN PEDIATRIC SEPTIC SHOCK: PERSEVERE II RISK AND MORTALITY (2020) (1)
- 104: A POTENTIAL NOVEL ROLE FOR OLFACTOMEDIN 4 IN SEPSIS (2014) (1)
- Gastroenterological, endocrine, renal, hematologic, oncologic and immune systems (2014) (1)
- 1002: A COMPREHENSIVE TIME-BASED META-ANALYSIS OF SIRS AND SEPSIS REVEALS A ROBUST DISCRIMINATORY GENE SET (2014) (1)
- EpitheliumGene Expression in Cultured Human Lung The Heat Shock Response Inhibits RANTES (1998) (1)
- Cardiac Troponin Measurement in the Critically Ill (2015) (0)
- THEAFLAVIN (BLACK TEA EXTRACT) IS A NOVEL ANTIINFLAMMATORY COMPOUND: 113 (2002) (0)
- EXTRACELLULAR HEAT SHOCK PROTEIN 70-MEDIATED PHAGOCYTOSIS.: 64 (2006) (0)
- CEREBROSPINAL FLUID NITRITE/NITRATE AND CEREBRAL BLOOD FLOW AFTER HUMAN HEAD INJURY. (1995) (0)
- 997: A PARSIMONIOUS TRANSCRIPTIONAL SIGNATURE CAN ROBUSTLY DISTINGUISH VIRAL FROM BACTERIAL INFECTIONS (2015) (0)
- 1440: ACUTE KIDNEY INJURY IS INDEPENDENTLY ASSOCIATED WITH POOR OUTCOMES IN CHILDREN WITH SEPTIC SHOCK (2020) (0)
- EPIGALLOCATECHIN-3-GALLATE (EGCG) INHIBITS IL-1β SIGNAL TRANSDUCTION: 38 (2002) (0)
- Transcriptional markers in response to hydrocortisone in sepsis in ADRENAL: a step toward precision medicine (2021) (0)
- Abstract 2353: Angiopoietin Expression in Children Following Cardiopulmonary Bypass (2007) (0)
- HYPOTHERMIA DECREASES GLUTAMATE, ASPARTATE AND 72-kDa HEAT SHOCK PROTEIN IN MENINGITIS (1999) (0)
- ELEVATED SERUM NITRATE LEVELS IN CHILDREN WITH THE SEPSIS SYNDROME (1994) (0)
- HEAT SHOCK ATTENUATES LPS-INDUCED TNF PRODUCTION VIA MKP-1 MEDIATED INHIBITION OF NUCLEAR P38 AND ERK ACTIVATION: 33 (2002) (0)
- EXOGENOUS HEAT SHOCK PROTEIN (HSP)70 REGULATES INTERLEUKIN-8 EXPRESSION IN HUMAN BRONCHIAL EPITHELIAL CELLS.: 135-T (2005) (0)
- Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery – A prospective observational cohort study (2023) (0)
- Pharmacologic Inhibition of Janus Kinase 1 and 2 Worsens Survival in Murine Sepsis (2019) (0)
- GELDANAMYCIN INHIBITS INTERLEUKIN-8 GENE EXPRESSION IN CULTURED HUMAN RESPIRATORY EPITHELIUM (1999) (0)
- 481: DELAYED ANTIBIOTIC ADMINISTRATION IN PEDIATRIC SEPTIC SHOCK IS ASSOCIATED WITH INCREASED ORGAN FAILURE DURATION (2012) (0)
- Genetic ablation of interleukin-10 enhances early stress response during ischemia and reperfusion injury in mice intestine (2001) (0)
- Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies (2022) (0)
- TYROSINE KINASE INHIBITION ATTENUATES SEPSIS-INDUCED VASOPLEGIA AND iNOS mRNA EXPRESSION IN RATS BUT DOES NOT AFFECT NF-kB NUCLEAR TRANSLOCATION (1999) (0)
- 7: EFFECT OF GENETIC ABLATION OF TIMP-1 ON SURVIVAL AND METALLOPROTEINASE LEVELS IN MURINE SEPSIS (2018) (0)
- ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE DEPRESSES NUCLEAR FACTOR‐KB AND ACTIVATOR PROTEIN‐1 ACTIVATION AND ENHANCES MYOCARDIAL APOPTOSIS IN ISCHEMIA AND REPERFUSION.: 233 (2001) (0)
- Corticosteroid Use Is Associated with Increased Mortality and Complicated Course in Pediatric Septic Shock (2014) (0)
- 1688: OLFACTOMEDIN-4-EXPRESSING NEUTROPHILS ARE ASSOCIATED WITH LOWER CD64 AND HYPERBILIRUBINEMIA (2019) (0)
- RESPIRATORY SYNCYTIAL VIRUS (RSV) INDUCES ENDO-TOXIN (LPS) TOLERANCE: 64 (2004) (0)
- Tu1435 – Matrix Metalloproteinases and Their Tissue Inhibitors Predict Severity in Pediatric Pancreatitis (2019) (0)
- 24: HIGH INCIDENCE OF NEUROIMAGING ABNORMALITIES AFTER PEDIATRIC SEPSIS (2015) (0)
- B-Dependent k through a TLR4- and NF-Cytokine Production in Airway Epithelium Hsp72 Induces Inflammation and Regulates (2007) (0)
- ABSTRACT 737: THERAPEUTIC CORTICOSTEROIDS ARE ASSOCIATED WITH GENOME-LEVEL REPRESSION OF ADAPTIVE IMMUNITY-RELATED GENE PROGRAMS IN PEDIATRIC SEPTIC SHOCK (2014) (0)
- The heat shock response inhibits phosphorylation of I-KBA (1999) (0)
- Genomics in Critical Illness (2014) (0)
- INDUCTION OF LIPOPOLYSACCHARIDE BINDING PROTEIN mRNA IN CULTURED RAT PULMONARY ARTERY SMOOTH MUSCLE CELLS BY INTERLEUKIN-l?? (1994) (0)
- HEAT SHOCK DEPENDENT REGULATION OF MKP-1: 68 (2004) (0)
- Endotoxin Tolerance in THP-1 Cells Extracellular Heat Shock Protein-70 Induces (2006) (0)
- 1018: GLUCOCORTICOID RECEPTOR EXPRESSION IN PEDIATRIC SEPTIC SHOCK (2015) (0)
- Multi-omic characterization of pediatric ARDS via nasal brushings (2022) (0)
- Regulation of hepatic NF‐κB activation during reperfusion after normothermic and hypothermic ischemia (2006) (0)
- EffECt of AppRopRiAtE initiAl AntifungAl thER- Apy foR CAndidEMiA on MoRtAlity in intEnsivE CARE units (2013) (0)
- INTERFERONS (IFNS) PROLONG LPS ACTIVATION OF THE NF??B PATHWAY.: 134 (2006) (0)
- 37: PERFORMANCE OF INTERLEUKIN 27 AS A SEPSIS DIAGNOSTIC BIOMARKER IN CRITICALLY ILL CHILDREN (2014) (0)
- INTRACATHETER NITROGLYCERIN FAILS TO PREVENT CATHETER-RELATED VENOUS THROMBOSIS: A RANDOMIZED, CONTROLLED TRIAL (1999) (0)
- Identification of a pediatric acute hypoxemic respiratory failure signature in peripheral blood leukocytes at 24 hours post-ICU admission with machine learning (2023) (0)
- REDUCED NF‐&kgr;B ACTIVATION AND HSP70 EXPRESSION MAY CONTRIBUTE TO AGE‐RELATED INCREASES IN ISCHEMIC LIVER INJURY.: 180 (2004) (0)
- THE ROLE OF EXTRACELLULAR HSP72 IN CARDIOMYOCYTE ACTIVATION.: 172 (2006) (0)
- EXTRACELLULAR HSP‐70: POTENTIAL ROLE IN ENDOTOXIN TOLERANCE.: 264 (2003) (0)
- 1813: AGE-RELATED MECHANISMS OF CARDIAC DYSFUNCTION IN SEPSIS (2019) (0)
- Epigallocatechin-3-gallate, a Green Tea–Derived Polyphenol, Inhibits IL-1 (cid:1) -Dependent Proinflammatory Signal Transduction in Cultured Respiratory Epithelial Cells 1,2 (2004) (0)
- 2299. Oral Microbiome of High-Risk Children: A Cohort Study (2018) (0)
- SESQUITERPENE LACTONES, INHIBITORS OF NUCLEAR FACTOR‐KB ACTIVATION, PREVENT CARDIOVASCULAR DYSFUNCTION IN ENDOTOXIC SHOCK.: 241 (2001) (0)
- Searching for a Pediatric Severe Sepsis Phenotype: We Might Indeed Be There. (2017) (0)
- 58: EBI3 GENETIC DEFICIENCY INCREASES LUNG AND SYSTEMIC INFLAMMATION IN MICE SUBJECTED TO SEPSIS (2014) (0)
- LPS PRECONDITIONING ATTENUATES THE HOST INFLAMMATORY RESPONSE AND IMPROVES SURVIVAL FOLLOWING CECAL LIGATION AND PUNCTURE IN MICE.: 189 (2006) (0)
- PERSEVEREBiomarkers Predict Severe Acute Kidney Injury andRenal Recovery in Pediatric Septic Shock (2020) (0)
- TEA FLAVANOIDS INHIBIT NOS2 EXPRESSION AND ACTIVITY IN VIVO AND IN VITRO: 468 (2004) (0)
- 1565: PCSK9 INHIBITION IS ASSOCIATED WITH METABOLIC DERANGEMENT IN THE JUVENILE HOST DURING SEPSIS (2020) (0)
- Olfactomedin-4 Positive Neutrophil Is Responsible for Increased Injury in Murine Intestinal Ischemia/Reperfusion Injury (2018) (0)
- 一種源自綠茶多酚~EGCG在培養的呼吸道上細胞中依賴IL-1ß促發炎性細胞信號傳遞作用之抑制 (2009) (0)
- 58: PERSISTENT SERUM RENIN ELEVATION IS ASSOCIATED WITH ACUTE KIDNEY INJURY IN PEDIATRIC SEPTIC SHOCK (2021) (0)
- ABSTRACT 232: GENE EXPRESSION DYNAMICS OF CRITICALLY ILL CHILDREN SUPPLEMENTED WITH INTRAVENOUS ZINC (2014) (0)
- PROSTAGLANDIN A1, A NONTHERMAL INDUCER OF THE HEAT SHOCK RESPONSE, INDUCES I-kappa B alpha GENE EXPRESSION (1998) (0)
- 1003: Nasal Transcriptomic and Serum Proteomic Identification of Three Pediatric ARDS Subtypes (2020) (0)
- Sepsis (2014) (0)
- MMP-8 Regulates the Inflammatory Response in Sepsis (2011) (0)
- INDUCTION OF iNOS GENE EXPRESSION VIA INTERLEUKIN‐1&bgr; IN CULTURED RAT PULMONARY ARTERY SMOOTH MUSCLE CELLS IS INHIBITED BY ARSENITE INDUCED HEAT SHOCK RESPONSE (1995) (0)
- in human neutrophils Effects of 30 min of aerobic exercise on gene expression (2015) (0)
- ENDOGENOUS INTERLEUKIN-10 ATTENUATES SPLANCHNIC ISCHEMIA-REPERFUSION INJURY IN MICE (1999) (0)
- 1538: IL27 AS A BIOMARKER TO DIAGNOSE BACTERIAL INFECTION IN IMMUNOCOMPROMISED PEDIATRIC PATIENTS (2018) (0)
- Corticosteroid Therapy for Septic Shock and Pediatric ARDS (2018) (0)
- ventila-A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study* (2017) (0)
- Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children (2014) (0)
- PP2A SCAFFOLDS AND REGULATES A JNK MAP KINASE SIGNALING COMPLEX: 272 (2002) (0)
- SESQUITERPENE LACTONES INHIBIT INTERLEUKIN-8 GENE EXPRESSION IN CULTURED HUMAN RESPIRATORY EPITHELIUM (1999) (0)
- Peri-operative care of the critically ill or injured child (2014) (0)
- DECREASED THERMOTOLERANCE FOLLOWING EXPOSURE TO GLYCOSYLATION INHIBITORS (1999) (0)
- The pediatric intensive care unit perspective on monitoring hemodynamics and oxygen transport (2011) (0)
- 1164: A BIOMARKER-BASED RISK STRATIFICATION TOOL FOR PEDIATRIC ACUTE RESPIRATORY DISTRESS SYNDROME (2018) (0)
- 800: IL-27 as a Novel Diagnostic Biomarker for Bacterial Infection in the Critically Ill (2013) (0)
- 1678: CRITICAL CARE DETERMINANTS OF POOR OUTCOME AMONG CHILDREN WITH SEPTIC SHOCK (2019) (0)
- IN VITRO MECHANICAL VENTILATION INDUCES HEAT SHOCK PROTEIN-70 EXPRESSION (1999) (0)
- Embracing Enrichment and Unknown Unknowns. (2018) (0)
- THERAPEUTIC EFFECT OF EPIGALLOCATECHIN GALLATE IN A MOUSE MODEL OF COLITIS.: 83 (2005) (0)
- Endotypes of Pediatric Acute Respiratory Distress Syndrome According to Gene Expression Profiles (2020) (0)
- Plasma Inflammatory Protein Profiles Distinguish Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS (2017) (0)
- Zinc Supplementation in Murine Sepsis (2015) (0)
- Nuclear factor-&kgr;B as a therapeutic target in critical care medicine (2003) (0)
- Random serum free cortisol and total cortisol measurements in pediatric septic shock (2018) (0)
- THE 5' FLANKING PROMOTER REGION OF MURINE INDUCIBLE NITRIC OXIDE SYNTHASE GENE MEDIATES INDUCTION BY INTERLEUKIN‐1&bgr; IN CULTURED RAT PULMONARY ARTERY SMOOTH MUSCLE CELLS (1995) (0)
- 1008: EFFECT OF ZINC SUPPLEMENTATION IN A MURINE MODEL OF STAPH AUREUS SUPERINFECTION AFTER H1N1 INFLUENZA (2014) (0)
- TGF-ALPHA-MEDIATED IL-8 EXPRESSION IN HUMAN LUNG EPITHELIAL CELLS: DEPENDENCE ON AP-1 AND INDEPENDENCE FROM NFKAPPAB: 274 (2002) (0)
- 819: QUALITY TRANSFORMATION LEADS TO SIGNIFICANT REDUCTIONS IN PICU AND HOSPITAL-WIDE STANDARDIZED MORTALITY RATIO (2012) (0)
- Hyperoxia Augments TNFα-Induced IL-8 Production in A549 Cells (1999) (0)
- Early Diagnosis of Sepsis: Is an Integrated Omics Approach the Way Forward? (2017) (0)
- ABSTRACT 255: THE EPIDEMIOLOGY OF STEROID USE IN CHILDREN WITH FLUID OR VASOACTIVE INFUSION DEPENDANT SHOCK (2014) (0)
- A Comparative Genomics Analysis Demonstrates a Distinct Molecular Signature for the Acute Respiratory Distress Syndrome (2015) (0)
- ALBUMIN INDUCES ENDOTOXIN TOLERANCE IN VITRO AND IN VIVO.: 137 (2006) (0)
- Development of a Risk Stratification Tool for Pediatric Acute Respiratory Distress Syndrome Using Peripheral Gene Expression (2020) (0)
- Hyperoxia Prolongs Tumor Necrosis Factor-&agr;-Mediated Activation Of NF-&kgr;B: Role Of I&kgr;B Kinase (2002) (0)
- GLUTAMINE ENHANCES HEAT SHOCK FACTOR-1 NUCLEAR TRANSLOCATION, PHOSHORYLATION AND PROMOTER BINDING FOLLOWING HEAT STRESS INJURY (2006) (0)
- HSP-70 PROTECTS HEPATOCYTES FROM ISCHEMIA/REPERFUSION INJURY (2006) (0)
- A Continuous Metric to Measure Endotype and Corticosteroid Interaction in Septic Shock (2021) (0)
- 268: CHARACTERIZATION OF GLUCOCORTICOID RECEPTOR EXPRESSION IN CD4 AND CD8 LYMPHOCYTES OF CRITICALLY ILL CHILDREN (2012) (0)
- 515: Improvement in Health-Related Quality of Life After Community-Acquired Pediatric Septic Shock (2020) (0)
- ADMISSION ANGIOPOIETIN-2 LEVELS IN CHILDREN WITH SEPTIC SHOCK.: 2 (2006) (0)
- ENDOGENOUS BACTERICIDAL/PERMEABILITY INCREASING PROTEIN LEVELS IN CHILDREN WITH THE SEPSIS SYNDROME (1995) (0)
- Abstract 1670: Extracellular Hsp72 and the Systemic Inflammatory Response to Cardiopulmonary Bypass (2007) (0)
- 205: MMP-8 AS A POTENTIAL THERAPEUTIC TARGET IN BACTERIAL PNEUMONIA (2012) (0)
- The Pediatric Sepsis Biomarker Risk Model (PERSEVERE) Biomarkers Predict Clinical Deterioration and Mortality in Immunocompromised Children Evaluated for Infection (2019) (0)
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