Robert Bruce Merrifield
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American biochemist
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Why Is Robert Bruce Merrifield Influential?
(Suggest an Edit or Addition)According to Wikipedia, Robert Bruce Merrifield was an American biochemist who won the Nobel Prize in Chemistry in 1984 for the invention of solid phase peptide synthesis. Early life He was born in Fort Worth, Texas, on 15 July 1921, the only son of George E. Merrifield and Lorene née Lucas. In 1923 the family moved to California where he attended nine grade schools and two high schools before graduating from Montebello High School in 1939. It was there that he developed an interest both in chemistry and in astronomy.
Robert Bruce Merrifield's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Solid phase peptide synthesis. I. the synthesis of a tetrapeptide (1963) (6370)
- Solid phase synthesis. (1986) (963)
- Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction. (1981) (908)
- All-D amino acid-containing channel-forming antibiotic peptides. (1990) (643)
- SOLID-PHASE PEPTIDE SYNTHESIS. 3. AN IMPROVED SYNTHESIS OF BRADYKININ. (1964) (492)
- An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis (1983) (480)
- Channel-forming properties of cecropins and related model compounds incorporated into planar lipid membranes. (1988) (467)
- Automated synthesis of peptides. (1965) (393)
- Prevention of insect-borne disease: an approach using transgenic symbiotic bacteria. (1997) (307)
- Synthesis of the antibacterial peptide cecropin A (1-33). (1982) (297)
- Binding and action of cecropin and cecropin analogues: antibacterial peptides from insects. (1988) (276)
- Solid-phase peptide synthesis. (1996) (269)
- Solid Phase Synthesis (Nobel Lecture) (1985) (268)
- Antibacterial and antimalarial properties of peptides that are cecropin‐melittin hybrids (1989) (268)
- A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis (1978) (246)
- Chemical synthesis of peptides and proteins. (1970) (245)
- Shortened cecropin A‐melittin hybrids Significant size reduction retains potent antibiotic activity (1992) (237)
- The total synthesis of an enzyme with ribonuclease A activity. (1969) (233)
- The synthesis of ribonuclease A. (1971) (231)
- Solid Phase Peptide Synthesis. II. The Synthesis of Bradykinin (1964) (215)
- Carboxyl-catalyzed intramolecular aminolysis. A side reaction in solid-phase peptide synthesis. (1972) (189)
- Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis. (1976) (189)
- A new amino protecting group removable by reduction. Chemistry of the dithiasuccinoyl (Dts) function. (1977) (188)
- N-terminal analogues of cecropin A: synthesis, antibacterial activity, and conformational properties. (1985) (183)
- Synthesis of Angiotensins by the Solid-Phase Method* (1965) (161)
- Instrument for automated synthesis of peptides. (1966) (161)
- Retro and retroenantio analogs of cecropin-melittin hybrids. (1995) (145)
- Antibacterial peptides designed as analogs or hybrids of cecropins and melittin. (2009) (142)
- Mechanisms for the removal of benzyl protecting groups in synthetic peptides by trifluoromethanesulfonic acid-trifluoroacetic acid-dimethyl sulfide (1986) (141)
- Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine. (1973) (141)
- Properties of swollen polymer networks. Solvation and swelling of peptide-containing resins in solid-phase peptide synthesis (1980) (135)
- Chemistry of the Amino Acids (1962) (133)
- The synthesis of bovine insulin by the solid phase method. (1966) (130)
- Automated Peptide Synthesis (1965) (119)
- Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. (1985) (116)
- Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist (1989) (112)
- Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method. (1975) (103)
- Solid-phase synthesis of cecropin A and related peptides. (1983) (103)
- 3 – Solid-Phase Peptide Synthesis (1976) (97)
- Concept and early development of solid-phase peptide synthesis. (1997) (96)
- Chemical synthesis and enzymic processing of precursor forms of cecropins A and B. (1989) (94)
- Synthetic peptide antagonists of glucagon. (1987) (92)
- SN 1 and SN 2 mechanisms for the deprotection of synthetic peptides by hydrogen fluoride. Studies to minimize the tyrosine alkylation side reaction. (2009) (90)
- Synthetic Melittin, Its Enantio, Retro, and Retroenantio Isomers, and Selected Chimeric Analogs: Their Antibacterial, Hemolytic, and Lipid Bilayer Action (1996) (90)
- Characterization of Deletion and Truncation Mutants of the Rat Glucagon Receptor (1995) (87)
- Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy. (1999) (82)
- Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. (1991) (80)
- Synthesis and antibacterial action of cecropin and proline-arginine-rich peptides from pig intestine. (2009) (80)
- Festphasen‐Synthese (Nobel‐Vortrag) (1985) (77)
- A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule. (1986) (75)
- Solid-phase synthesis of PYLa and isolation of its natural counterpart, PGLa [PYLa-(4-24)] from skin secretion of Xenopus laevis. (1985) (74)
- Azide solid phase peptide synthesis. (1970) (74)
- Preparation of aminomethyl-polystyrene resin by direct amidomethylation (1976) (71)
- Secretin stimulates cyclic AMP and inositol trisphosphate production in rat pancreatic acinar tissue by two fully independent mechanisms. (1987) (71)
- Zinc chloride-catalyzed chloromethylation of resins for solid phase peptide synthesis (1974) (70)
- Quantitative determination of D- and L-amino acids by reaction with tert-butyloxycarbonyl-L-leucine N-hydroxysuccinimide ester and chromatographic separation as L,D and L,L dipeptides (1978) (70)
- Reactivation of des (119-124) ribonuclease A by mixture with synthetic COOH-terminal peptides; the role of phenylalanine-120. (1972) (69)
- The beta-phenacyl ester as a temporary protecting group to minimize cyclic imide formation during subsequent treatment of aspartyl peptides with HF. (2002) (69)
- Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling. (2009) (68)
- Modification of peptides containing glutamic acid by hydrogen fluoride-anisole mixtures. Gamma-acylation of anisole or the glutamyl nitrogen. (1975) (67)
- Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis. (1973) (66)
- The chemical synthesis of cecropin D and an analog with enhanced antibacterial activity. (1989) (65)
- Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase. (1989) (64)
- Design, synthesis and antibacterial activity of cecropin-like model peptides. (2009) (63)
- A quantitative evaluation of methods for coupling asparagine (1980) (60)
- D-enantiomers of 15-residue cecropin A-melittin hybrids. (2009) (59)
- Enhancement of peptide coupling reactions by 4-dimethylaminopyridine. (2009) (58)
- On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia. (1985) (58)
- Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding. (1996) (58)
- Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase (2001) (57)
- The synthesis of deamino-oxytocin by the solid phase method. (1968) (56)
- Identification of an essential serine residue in glucagon: implication for an active site triad. (1994) (55)
- 9-(2-Sulfo)fluorenylmethyloxycarbonyl chloride, a new reagent for the purification of synthetic peptides (1978) (54)
- Synthesis of a hydrophobic potassium binding peptide. (1972) (54)
- Long-chain polystyrene-grafted polyethylene film matrix: a new support for solid-phase peptide synthesis (1989) (53)
- Chlorotrimethylsilane-phenol as a mild deprotection reagent for the tert-butyl based protecting groups in peptide synthesis (1988) (53)
- Specific peptide sequences for metal ion coordination. 1. Solid-phase synthesis of cyclo-(Gly-His)3 (1982) (52)
- Cyclohexyl ester as a new protecting group for aspartyl peptides to minimize aspartimide formation in acidic and basic treatments (1980) (51)
- Improved synthesis of 4-alkoxybenzyl alcohol resin (1981) (50)
- Design and synthesis of multidetachable resin supports for solid-phase peptide synthesis (1980) (50)
- Improved Synthesis of 4-(Boc-aminoacyloxymethyl)-phenylacetic Acids for use in Solid Phase Peptide Synthesis (1979) (49)
- Effects on electrophoretic mobility and antibacterial spectrum of removal of two residues from synthetic sarcotoxin IA and addition of the same residues to cecropin B (1988) (48)
- Mechanisms of aspartimide formation: the effects of protecting groups, acid, base, temperature and time. (1988) (48)
- The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs. (1975) (48)
- Regeneration of activity by mixture of ribonuclease enzymically degraded from the COOH terminus and a synthetic COOH-terminal tetradecapeptide. (1970) (47)
- Use of N-im-dinitrophenylhistidine in the solid-phase synthesis of the tricosapeptides 124-146 of human hemoglobin beta chain. (1969) (47)
- Hydrophobic Effects on Antibacterial and Channel‐forming Properties of Cecropin A–Melittin Hybrids (1996) (47)
- Solid Phase Peptide Synthesis. IV. The Synthesis of Methionyl-lysyl-bradykinin1 (1964) (47)
- Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling. (2002) (47)
- Solid-phase synthesis of thymosin alpha 1 using tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin. (1980) (45)
- The role of histidine-1 in glucagon action. (1993) (45)
- Reactivation of des(119-, 120-, or 121-124) ribonuclease A by mixture with synthetic COOH-terminal peptides of varying lengths. (1972) (44)
- Mass spectrometric evaluation of synthetic peptides as primary structure models for peptide and protein deamidation. (2001) (44)
- Design and synthesis of antimicrobial peptides. (2007) (44)
- Preparation of a tert-alkyloxycarbonylhydrazide resin and its application to solid phase peptide synthesis (1969) (43)
- The Synthesis of L-Seryl-L-histidyl-L-leucyl-L-valyl- L-glutamic Acid, a Peptide with Strepogenin Activity (1956) (43)
- Solid-phase synthesis of crystalline glucagon. (1981) (42)
- Mass spectrometric evaluation of synthetic peptides for deletions and insertions. (1988) (42)
- Preparation of some new biphenylisopropyloxycarbonyl amino acids and their application to the solid phase synthesis of a tryptophan-containing heptapeptide of bovine parathyroid hormone. (2009) (41)
- Concept of internal structural controls for evaluation of inactive synthetic peptide analogs: synthesis of [Orn13,14]apamin and its guanidination to an apamin derivative with full neurotoxic activity. (1977) (41)
- Multiple-site replacement analogs of glucagon. A molecular basis for antagonist design. (1994) (39)
- Detection and prevention of urethane acylation during solid-phase peptide synthesis by anhydride methods. (1974) (39)
- Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis. (1979) (38)
- Solid Phase Peptide Synthesis. VI. The Use of the o-Nitrophenylsulfenyl Group in the Synthesis of the Octadecapeptide Bradykininylbradykinin* (1966) (38)
- Solid-phase synthesis of the cyclododecadepsipeptide Valinomycin. (1969) (37)
- Selective deprotection of the N.alpha.-tert-butyloxycarbonyl group in solid phase peptide synthesis with chlorotrimethylsilane in phenol (1993) (36)
- The role of the support in solid phase peptide synthesis (1984) (36)
- Solid phase synthesis of bovine pituitary growth hormone-(123-131) nonapeptide. (2009) (36)
- Synthesis and study of normal, enantio, retro, and retroenantio isomers of cecropin A-melittin hybrids, their end group effects and selective enzyme inactivation. (2009) (35)
- Kinetics and Mechanism of the Thiolytic Removal of the Dithiasuccinoyl (Dts) Amino Protecting Group (1980) (35)
- Affinity purification of synthetic peptides. (1976) (34)
- Molecular basis of superreactivity of cysteine residues 31 and 32 of seminal ribonuclease. (1985) (34)
- Glucagon antagonists: contribution to binding and activity of the amino-terminal sequence 1-5, position 12, and the putative alpha-helical segment 19-27. (1989) (34)
- Chemical studies of histone acetylation. Substrate specificity of a histone deacetylase from calf thymus nuclei. (1974) (31)
- Life during a golden age of peptide chemistry : the concept and development of solid-phase peptide synthesis (1993) (29)
- Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase. (1977) (29)
- A chromatographic method for the quantitative analysis of the deprotection of dithiasuccinoyl (Dts) amino acids. (1979) (28)
- Specificity of Peptides (1958) (28)
- Roles of aspartic acid 15 and 21 in glucagon action: receptor anchor and surrogates for aspartic acid 9. (1994) (27)
- Antibacterial Immune Proteins in Insects — A Review of Some Current Perspectives (1986) (27)
- Structure-immunogenicity relationship of melittin, its transposed analogues, and D-melittin. (1994) (27)
- Positively Charged Residues at Positions 12, 17, and 18 of Glucagon Ensure Maximum Biological Potency* (1998) (26)
- New approaches to the chemical synthesis of peptides. (1967) (26)
- Synthetic study of the effect of tyrosine at position 120 of ribonuclease. (2009) (26)
- A solid phase-fragment approach to peptide synthesis. The application of a t-alkyloxycarbonylhydrazide resin and a t-alkyl alcohol resin. (2009) (25)
- A general approach to the quantitation of synthetic efficiency in solid-phase peptide synthesis as a function of chain length (1984) (25)
- Selective Stabilization of the High Affinity Binding Conformation of Glucagon Receptor by the Long Splice Variant of Gαs * (2000) (25)
- Solid phase synthesis of gastrin I. Comparison of methods utilizing strong acid for deprotection and cleavage. (2009) (24)
- Preparation of pancreatic ribonucleases 1-114 and 1-115 and their reactivation by mixture and synthetic COOH-terminal peptides. (1973) (24)
- The synthesis of biphenylisopropyloxycarbonyl-amino acid salts (1972) (24)
- The Isolation and Determination of Structure of Peptides with Strepogenin Activity. I. Serylhistidylleucylvalylglutamic Acid and Serylhistidylleucylvalylglutamylalanylleucine from Insulin (1956) (22)
- Improved deprotection in solid phase peptide synthesis: quantitative reduction of methionine sulfoxide to methionine during HF cleavage (1982) (22)
- The Synthesis of Peptides with Strepogenin Activity1 (1958) (21)
- The synthesis of biologically active peptides and proteins. (1969) (20)
- Tyrosine protecting groups: minimization of rearrangement to 3-alkyltyrosine during acidolysis (1978) (20)
- Test for Racemization in Model Peptide Synthesis by Direct Chromatographic Separation of Diastereomers of the Tetrapeptide Leucylalanylglycylvaline (1978) (20)
- Efficient synthesis of 1,2,4-dithiazolidine-3,5-diones [dithiasuccinoyl-amines] from bis(chlorocarbonyl)disulfane plus bis(trimethylsilyl)amines. (2005) (20)
- Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis. (2009) (19)
- Improved deprotection in solid phase reptide synthesis: removal of protecting groups from synthetic peptides by an SN2 mechanism with low concentrations of HF in dimethylsulfide (1982) (19)
- Occurrence of N-alkylation during the acidolytic cleavage of urethane protecting groups (1976) (19)
- Glucagon antagonists. Synthesis and inhibitory properties of Asp3-containing glucagon analogs. (1987) (19)
- AUTOMATED SOLID PHASE SYNTHESIS OF THYMOSIN α1 (2009) (19)
- An improved synthesis of crystalline mammalian glucagon. (1984) (19)
- Solid phase synthesis (1985) (18)
- A new base-catalyzed cleavage reaction for the preparation of protected peptides (1984) (18)
- CHAPTER 3 – Solid Phase Synthesis: The Use of Solid Supports and Insoluble Reagents in Peptide Synthesis (1971) (18)
- The chemical synthesis of proteins (1996) (18)
- Synthetic peptides VH(27-68) and VH(16-68) of the myeloma immunoglobulin M603 heavy chain and their association with the natural light chain to form an antigen binding site. (1987) (17)
- SOLID-PHASE PEPTIDE SYNTHESES. (1965) (17)
- ANOMALIES OF THE STRUCTURAL SPECIFICITY OF PEPTIDES (1963) (17)
- Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH (4-10) core sequence. (1973) (17)
- Strategic Alliances in the Global Marketplace (1989) (17)
- The overriding importance of R&D as it relates to industrial competitiveness (1989) (16)
- HIGH STREPOGENIN POTENCY OF SYNTHETIC OXYTOCIN AND OF PURIFIED VASOPRESSIN (1954) (16)
- Isolation of A- and B-chain sulfonates of insulin by countercurrent distribution (1967) (16)
- Synthesis of a cyclic analog of oxidized glutathione by an intersite reaction in a swollen polymer network (1983) (14)
- Selective cleavage of protected amino acids and peptides from oxyacyl resins by an 18-crown-6 complex of potassium cyanide (1978) (14)
- Solid phase synthesis of the protected 27--42 hexadecapeptide of the heavy chain from myeloma immunoglobulin M603. Elimination of side reactions associated with glycyl-2-oxypropionyl-resin. (2009) (14)
- Stability of Side‐Chain Protecting Groups in Solid‐Phase Peptide Synthesis (1975) (14)
- Potentiation of glucose-induced insulin release in islets by desHis1[Glu9]glucagon amide. (2009) (13)
- A Study of the Edman Degradation in the Assessment of the Purity of Synthetic Peptides (1982) (13)
- The amino acid sequences of the biotinyl subunit essential for the association of transcarboxylase. (1982) (13)
- Strong Acid Deprotection of Synthetic Peptides: Mechanisms and Methods (1988) (13)
- Chemical mechanism to account for artifactual formation of shortened peptides with free alpha-amino groups in solid phase peptide synthesis. (2009) (12)
- Solid phase peptide synthesis after 25 years: The design and synthesis of antagonists of glucagon (1988) (12)
- TYROSINE PROTECTING GROUPS- MINIMIZATION OF REARRANGEMENT TO 3-ALKYLTYROSINE DURING ACIDOLYSIS (1978) (12)
- Design and synthesis of a multi-detachable benzhydrylamine-resin for solid phase peptide synthesis (1981) (11)
- Synthetic position 5 analogs of adrenocorticotropin fragments and their in vitro lipolytic activity. (1975) (11)
- Synthetic Melittin, Its Enantio, Retro, and Retroenantio Isomers, and Selected Chimeric Analogues: Their Antibacterial, Hemolytic, and Lipid Bilayer Action. (2010) (10)
- The synthesis of diacetylated histone H4-(1–37) for studies on the mechanism of histone deacetylation (1979) (10)
- Solid phase synthesis of the protected 43-55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid. (2009) (10)
- Biopolymer synthesis on solid supports (1978) (9)
- Improved deprotection in solid phase peptide synthesis: deprotection of Ni-formyl-tryptophan to tryptophan in low concentrations of HF in Me2S–p- thiocresol mixtures (1982) (9)
- An ATP-Binding Peptide (1973) (9)
- Design and Synthesis of Antimicrobial Peptides (1996) (9)
- Industrial project selection and management (1978) (9)
- Structure-activity studies of normal and retro pig cecropin-melittin hybrids. (1999) (8)
- Multi-detachable resin supports for solid phase fragment synthesis (1980) (8)
- Science Over Politics (1999) (8)
- DETECTION AND PREVENTION OF URETHANE ACYLATION DURING SOLID-PHASE PEPTIDE SYNTHESIS BY ANHYDRIDE METHODS (1974) (8)
- Synthesis and hormonal activity of [Tyr22] glucagon and [desHis1, Tyr22] glucagon. (2009) (8)
- The Chemical Synthesis of Glucagon (1983) (8)
- Automated solid phase synthesis of thymosin alpha 1. (1980) (8)
- Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports. (2009) (8)
- The limits of reaction of radioactive dicyclohexylcarbodiimide with amino groups during solid-phase peptide synthesis. (1977) (7)
- Insulin release by glucagon and secretin: studies with secretin-glucagon hybrids. (1988) (7)
- 4-Methoxybenzyloxycarbonyl amino acids in solid phase peptide synthesis. (1988) (7)
- Synthesis of O-methyl-L-serine and Nalpha-tert-butyloxycarbonyl-O-methyl-L-serine. (1974) (7)
- A NEW AMINO PROTECTING GROUP REMOVABLE BY REDUCTION. CHEMISTRY OF THE DITHIASUCCINOYL (DTS) FUNCTION (1978) (7)
- Opioid activity of synthetic and naturally occurring enkephalin peptides. (1979) (7)
- Strepogenin Activity of Synthetic Peptides Related to Oxytocin (1955) (7)
- The microbiological determination of pyrimidines with lactobacilli. (1950) (6)
- Improved deprotection of cysteine‐containing peptides in HF (2009) (6)
- Preparation and Properties of tert-Butyloxycarbonylaminoacyl-4-(oxymethyl) phenylacetamidomethyl-(Kel F-g-styrene) Resin, an Insoluble, Noncrosslinked Support for Solid Phase Peptide Synthesis (1978) (6)
- Selective Deprotection of the Nα‐tert‐Butyloxycarbonyl Group in Solid Phase Peptide Synthesis with Chlorotrimethylsilane and Phenol. (1994) (6)
- Competitive inhibition of a strepogenin-active peptide by related peptides. (1958) (5)
- TERT-BUTOXYCARBONYLAMINOACYL-4-(OXYMETHYL)PHENYLACETAMIDOMETHYL-RESIN, A MORE ACID-RESISTANT SUPPORT FOR SOLID-PHASE PEPTIDE SYNTHESIS (1977) (5)
- Antibacterial, conformational and membrane-active properties of small size cecropin A-melittin hybrids (1993) (5)
- The cecropins: An example of the use of peptide synthesis to study a biochemical problem (1991) (5)
- Kinetics of coupling reactions in solid phase peptide synthesis (1988) (4)
- The relation of predicted structure to observed conformation and activity of glucagon analogs containing replacements at positions 19, 22, and 23. (1987) (4)
- Effects of cecropin and melittin analogs and hybrids on pro- and eucaryotic cells. (1990) (4)
- The antifungal activity of carrier peptides, L-arginyl-X-L-phenylalanine, containing amino acid antagonists or atypical non-biogenic D-amino acids in the central position. (1982) (4)
- Chlorotrimethylsilane - Phenol as a Mild Deprotection Reagent for the tert-Butyl Based Protecting Groups in Peptide Synthesis. (1988) (4)
- Nobel laureates' letter to President Bush. (2001) (3)
- Glucagon I (1983) (3)
- Mechanisms for the Removal of Benzyl Protecting Groups in Synthetic Peptides by Trifluoromethanesulfonic Acid - Trifluoroacetic Acid - Dimethyl Sulfide. (1986) (3)
- The design and synthesis of glucagon antagonists (1993) (3)
- Peptide Antibiotics from the Animal Kingdom: Cecropins and Synthetic Analogs (1991) (3)
- Concept and Early Development of Solid-Phase Peptide Synthesis (1998) (3)
- Synthesis and Characterization of Immunoglobulin Variable Region Heavy and Light Chain Fragments (1992) (2)
- Stimulating Technological Innovation: Nurturing the Inventor (1979) (2)
- The automatic synthesis of proteins. (1968) (2)
- Microbiological determination of cytosine, uracil and thymine. (1948) (2)
- The determination of proline in protein hydrolysates with Lactobacillus brevis. (1949) (2)
- Isolation and determination of structure of a peptide with strepogenin activity. (1955) (2)
- The structure and microbiological activity of some dinucleotides isolated from yeast ribonucleic acid. (1952) (2)
- Peptide science. Comprehensive reports & reviews. Introduction. (1995) (2)
- Chlorotrimethylsilane-phenol as a selective deprotection reagent for the tert-butyloxycarbonyl group (1988) (1)
- All-D aminoacid-containing channel-forming antibiotic peptides (Denantiomeric peptides/antimalarial peptides/cecropin/magainin/melittin) (1990) (1)
- The development of ball valves (1985) (1)
- Retroandretroenantio analogs ofcecropin-melitti n hybrids (antibacterial peptides/all-D peptides/peptide topology) (1995) (1)
- β-PHENACYL ESTER AS A TEMPORARY PROTECTING GROUP TO MINIMIZE CYCLIC IMIDE FORMATION DURING SUBSEQUENT TREATMENT OF ASPARTYL PEPTIDES WITH HYDROFLUORIC ACID (1976) (1)
- Solid phase peptide synthesis: New chemistry and new directions (1999) (1)
- The chemical synthesis of an enzyme. (1973) (1)
- USE OF CHLORINATED BENZYLOXYCARBONYL PROTECTING GROUPS TO ELIMINATE N(EPSILON)-BRANCHING AT LYSIN DURING SOLID-PHASE PEPTIDE SYNTHESIS (1973) (1)
- Synthesis and study of all-L and all-D normal and retro isomers of cecropin A-melittin hybrids and selective enzyme inactivation (2002) (1)
- Synthesis, purification, NMR characterization and interaction with nucleotides of a fragment of fish protamines. (1990) (1)
- Antibody binding Constants by Capillary electrophoresis (1994) (1)
- Positively charged residues of glucagon: Role in glucagon action (2002) (1)
- Preparation and use of 2-t-butoxyphenol for the synthesis of monoaminoacyl catechol derivatives (1991) (1)
- Remarks on peptide chemistry (1994) (1)
- Synthetic Studies on the Cecropins (1983) (1)
- Retroandretroenantio analogs ofcecropin-melitti n hybrids (antibacterial peptides/all-D peptides/peptide topology) (1995) (1)
- SOLID PHASE SYNTHESIS OF BOVINE PITUITARY GROWTH HORMONE-(123-131) NONAPEPTIDE (1974) (1)
- Affinity purification of synthetic peptides [ solid-phase peptide synthesis / Cys-Met-peptides / organomercurial-agarose / ribonuclease A ( 111-124 ) tetradecapeptide / histone H 441-37 ) heptatriacontapeptidej (2003) (0)
- Synthetic studies on the cecropin antibacterial peptides (1993) (0)
- Oral history interview with Walter B. LaBerge (1968) (0)
- Oral history interview with Dave W. Lang (1967) (0)
- Replacement of d-amino acids with l-amino acids in the Cecropin A-Melittin hybrid, all-d CA(1–13)M(1–13)NH 2, produces anomalous effects on antibacterial activities (1994) (0)
- Peptide synthesis and solid support for use therein. (1989) (0)
- Modification of peptides containing glutamic acid by hydrogen fluoride-anisole mixtures. .gamma.-Acylation of anisole or the glutamyl nitrogen (1975) (0)
- Identification ofanessential serine residue inglucagon: Implication foranactive site triad (1994) (0)
- Glucagon antagonist design based on replacement of active site triad residues (1994) (0)
- A method for synthesizing a peptide or protein, and a method EV yttökelpoinen polymer substrate grafted with polystyrene chains (1991) (0)
- SYNTH. EINES HYDROPHOBEN, KALIUM BINDENDEN PEPTIDS (1972) (0)
- Solid phase synthesis of thymosin β9 (2009) (0)
- Film-supported solid-phase peptide synthesis (1990) (0)
- Reactivation of des (119-, 126, or 121-124) by Mixture with Synthetic COOKterminal Peptides of Varying Lengths* Ribonuclease A (1972) (0)
- Oral history interview with Howard C. Bedford, Jr. (1968) (0)
- McPC603 V H(1–115): Synthesis and folding of immunoglobulin variable regions (1994) (0)
- Glucagon receptor structure and function: Probing the putative hormone binding site with receptor chimeras (2002) (0)
- Syntheses and antibacterial activities of tetrameric cecropin-melittin hybrid analogs (1993) (0)
- The first extracellular loop of the rat glucagon receptor contains determinants of glucagon binding (1999) (0)
- PYLa and a PYLa-melittin hybrid are antibacterial peptides (1992) (0)
- Peptide biology progress and prospects (1991) (0)
- THE SYNTHESIS OF PEPTIDES AND PROTEINS BY THE SOLID PHASE METHOD (1971) (0)
- PREPARATION OF AMINOMETHYL‐POLYSTYRENE RESIN BY DIRECT AMIDOMETHYLATION (1977) (0)
- Oral history interview with Joseph P. Loftus (1971) (0)
- Solid phase synthesis of thymosin beta 9. (1986) (0)
- Specificity of position 9 for glucagon activity (1991) (0)
- Role of Ile8 on the antibacterial and channel forming properties of shortened cecropin A - melittin hybrids (1994) (0)
- Site-Specific Fluorescent-Labeled Glucagon Analogs: Probes for the Glucagon Receptor, (1992) (0)
- Solid-Phase Peptide Synthesis After 25 Years: The Design and Synthesis of Antagonists of Glucagon (1989) (0)
- Solid-phase synthesis ofcecropin A andrelated peptides (antibacterial peptides/(Phe'lcecropin A/des-Lys',Trp2-cecropin (1983) (0)
- LIPOLYTIC ACTIVITY OF MET-ARG-HIS-PHE-ARG-TRP-GLY, A SYNTHETIC ANALOG OF THE ACTH (4-10) CORE SEQUENCE (1974) (0)
- Peptide Synthesis: The Peptides, Methods of Peptide Synthesis , volume 1. By Eberhard Schroder and Klaus Lübke. Academic Press, New York, 1965. 511 pp., $18. (1966) (0)
- IMPROVED DEPROTECTION IN SOLID PHASE PEPTIDE SYNTHESIS: REMOVAL OF PROTECTING GROUPS FROM SYNTHETIC PEPTIDES BY AN SN2 MECHANISM WITH LOW CONCENTRATIONS OF HYDROGEN FLUORIDE IN DIMETHYL SULFIDE (1983) (0)
- IMPROVED SYNTHESIS OF 4-(BOC-AMINOACYLOXYMETHYL)PHENYLACETIC ACIDS FOR USE IN SOLID PHASE PEPTIDE SYNTHESIS (1980) (0)
- CARBOXYL-KATALYSIERTE INTRAMOLEKULARE AMINOLYSE, NEBENRK. BEI DER FESTPHASEN-PEPTID-SYNTH. (1972) (0)
- STRATI-BISPORPHYRINS. A NOVEL CYCLOPHANE SYSTEM (1977) (0)
- Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenas 4 ( 3-hydroxyaspartic acid / epidermal growth factor-like domains ) (0)
- IMPROVED DEPROTECTION IN SOLID PHASE PEPTIDE SYNTHESIS: QUANTITATIVE REDUCTION OF METHIONINE SULFOXIDE TO METHIONINE DURING HYDROGEN FLUORIDE CLEAVAGE (1982) (0)
- DESIGN AND SYNTHESIS OF A MULTIDETACHABLE BENZHYDRYLAMINE RESIN FOR SOLID PHASE PEPTIDE SYNTHESIS (1981) (0)
- SYNTHESIS OF O-METHYL-L-SERINE AND N(ALPHA)-TERT-BUTYLOXYCARBONYL-O-METHYL-L-SERINE (1974) (0)
- THE LIMITS OF REACTION OF RADIOACTIVE DICYCLOHEXYLCARBODIIMIDE WITH AMINO GROUPS DURING SOLID-PHASE PEPTIDE SYNTHESIS (1977) (0)
- Improved Deprotection of Cysteine-Containing Peptides in HF. (1987) (0)
- ACID STABILITY OF SEVERAL BENZYLIC PROTECTING GROUPS USED IN SOLID-PHASE PEPTIDE SYNTHESIS, REARRANGEMENT OF O-BENZYLTYROSINE TO 3-BENZYLTYROSINE (1973) (0)
- Questions and Answers From IRI's Members (2012) (0)
- Collaboration across vertical boundaries: lessons learned from the US DOE's SPI programme (2014) (0)
- [Demonstration of a new action of thiamine by the use of pyrithiamine]. (1954) (0)
- Helical character and aggregation effects on the activity of short cecropin-melittin hybrid peptides (1994) (0)
- Nurturing the Inventor : R&D Management (1988) (0)
- TIME FOR A SUPPLY CHAIN REVOLUTION (2000) (0)
- Electronic Waste Management: Design, Analysis, and Application edited by Ronald E. Hester and Roy M. Harrison (2010) (0)
- Emissions a case for the FEDs (1999) (0)
- Introduction (0)
- SOLID PHASE SYNTHESIS (OF PROTEINS) (1985) (0)
- Peptides and polymers: An ongoing affair (1989) (0)
- Perspectives for the new peptide millennium (2002) (0)
- Solid phase synthesis of gastrin I (2008) (0)
- Book Review: Peptides: Chemistry and Biology By Norbert Sewald and Hans-Dieter Jakubke (2003) (0)
- Synthesis and Study of the Antimicrobial Action of Cecropin A-Melittin Hybrids with Aib Substitution (2001) (0)
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