Donald Metcalf

Q: What Schools Are Affiliated With Donald Metcalf

Donald Metcalf is affiliated with the following schools: University of Sydney, University of Melbourne, University of Western Australia, Monash University

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Donald Metcalf

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#407

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Philosophy

Donald Metcalf's Degrees

Bachelors Medicine University of Melbourne
Doctorate Medicine University of Melbourne

Why Is Donald Metcalf Influential?

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According to Wikipedia, Donald Metcalf AC FRS FAA was an Australian medical researcher who spent most of his career at the Walter and Eliza Hall Institute of Medical Research in Melbourne. In 1954 he received the Carden Fellowship from the Anti-Cancer Council of Victoria; while he officially retired in 1996, he continued working and held his fellowship until his death in December 2014.

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Donald Metcalf's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A family of cytokine-inducible inhibitors of signalling (1997) (2152)
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells (1988) (2070)
The growth of mouse bone marrow cells in vitro. (1966) (1905)
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. (1999) (1633)
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells (1989) (1079)
Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo * (1970) (1049)
Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. (1994) (944)
Programmed Anuclear Cell Death Delimits Platelet Life Span (2007) (925)
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. (2013) (896)
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. (1994) (891)
SOCS3 negatively regulates IL-6 signaling in vivo (2003) (861)
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo (2007) (847)
SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine (1999) (820)
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. (1995) (815)
The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors. (1986) (801)
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. (1996) (762)
Twenty proteins containing a C-terminal SOCS box form five structural classes. (1998) (753)
Growth of factor-dependent hemopoietic precursor cell lines (1980) (697)
Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes (2006) (671)
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. (1999) (654)
Granulocyte-macrophage colony-stimulating factors (1985) (626)
Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. (1995) (615)
Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (2014) (610)
Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients. (1988) (600)
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome (2002) (569)
Purification and properties of colony-stimulating factor from mouse lung-conditioned medium. (1977) (556)
Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl. (1996) (549)
The nature and action of granulocyte-macrophage colony stimulating factors. (1980) (532)
Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). (1987) (516)
Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor. (1983) (506)
Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia (1984) (498)
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. (2000) (493)
Hematopoietic regulators: redundancy or subtlety? (1993) (489)
Gigantism in mice lacking suppressor of cytokine signalling-2 (2000) (484)
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. (1998) (483)
Granulocyte-macrophage colony-stimulating factors (1985) (478)
The hemopoietic colony stimulating factors (1984) (474)
RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis (2014) (465)
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL‐6 signal transduction (1999) (464)
Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. (1986) (460)
Hematopoietic cytokines. (2008) (452)
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. (1996) (433)
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. (1998) (402)
Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor (1984) (401)
Stimulation by human placental conditioned medium of hemopoietic colony formation by human marrow cells. (1977) (395)
Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. (1991) (388)
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. (1999) (376)
Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. (1983) (376)
Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage (1987) (372)
In vitro colony formation by normal and leukemic human hematopoietic cells: characterization of the colony-forming cells. (1973) (365)
Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors (2005) (339)
Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant. (1998) (328)
Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice. (1986) (326)
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3 (2001) (325)
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance (2006) (316)
Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics. (1974) (314)
Pure and mixed erythroid colony formation in vitro stimulated by spleen conditioned medium with no detectable erythropoietin. (1977) (313)
Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5. (1995) (306)
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis (2005) (301)
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity (2006) (295)
SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. (2004) (292)
The influence of granulocyte/macrophage colony‐stimulating factor on dendritic cell levels in mouse lymphoid organs (1997) (288)
Hierarchical down-modulation of hemopoietic growth factor receptors (1985) (285)
Hemopoietic responses in mice injected with purified recombinant murine GM-CSF. (1987) (282)
Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors. (1986) (274)
Cloning of a murine IL‐11 receptor alpha‐chain; requirement for gp130 for high affinity binding and signal transduction. (1994) (271)
A transplantable myelomonocytic leukemia in BALB-c mice: cytology, karyotype, and muramidase content. (1969) (270)
Growth of mouse megakaryocyte colonies in vitro. (1975) (265)
Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor. (1989) (260)
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. (2012) (254)
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells (2008) (249)
The Unsolved Enigmas of Leukemia Inhibitory Factor (2003) (245)
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12 (2003) (245)
Lineage commitment and maturation in hematopoietic cells: the case for extrinsic regulation. (1998) (244)
Effects of injected leukemia inhibitory factor on hematopoietic and other tissues in mice. (1990) (237)
Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism (1985) (232)
Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells (1985) (229)
Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor (1970) (229)
SOCS2 negatively regulates growth hormone action in vitro and in vivo. (2005) (229)
Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity (1985) (228)
Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells (1983) (228)
Subunit promiscuity among hemopoietic growth factor receptors (1991) (225)
Activation of antibody-dependent cell-mediated cytotoxicity of human neutrophils and eosinophils by separate colony-stimulating factors. (1983) (225)
Production of colony-stimulating factors (CSFs) during infection: separate determinations of macrophage-, granulocyte-, granulocyte-macrophage-, and multi-CSFs (1988) (224)
Binding of 125I‐labeled granulocyte colony‐stimulating factor to normal murine hemopoietic cells (1985) (214)
Production of colony-stimulating factor in mitogen-stimulated lymphocyte cultures. (1974) (208)
Hemopoietic colonies: in vitro cloning of normal and leukemic cells. (1977) (202)
The leukemia inhibitory factor (LIF). (1991) (199)
Acute antigen-induced elevation of serum colony stimulating factor (CFS) levels. (1971) (199)
Stimulation by normal and leukemic mouse sera of colony formation in vitro by mouse bone marrow cells (1967) (199)
Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling. (2004) (194)
Cytokine receptor expression on hematopoietic stem and progenitor cells. (1997) (193)
Effects of bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor in patients with advanced malignancy. (1989) (191)
Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors. (1991) (187)
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo (2001) (186)
Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor. (1988) (183)
Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors. (1983) (182)
Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease (2006) (182)
Biological Evidence That SOCS-2 Can Act Either as an Enhancer or Suppressor of Growth Hormone Signaling* (2002) (176)
A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte‐macrophage colony stimulating factor. (1989) (174)
Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets (2011) (170)
Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells. (1980) (170)
A low molecular weight factor in lung‐conditioned medium stimulating granulocyte and monocyte colony formation in vitro (1973) (167)
Separation of functionally distinct human granulocyte-macrophage colony-stimulating factors. (1979) (167)
Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells (1980) (166)
Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b). (2002) (165)
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. (1999) (162)
Colony formation in agar by multipotential hemopoietic cells (1979) (161)
A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis. (2008) (158)
The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects. (1999) (156)
The Thymic Origin of the Plasma Lymphocytosis Stimulating Factor (1956) (154)
Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor. (1996) (154)
Growth of B-lymphocyte colonies in vitro (1975) (152)
Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. (2006) (151)
SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation (2002) (150)
In vitro actions on hemopoietic cells of recombinant murine GM‐CSF purified after production in Escherichia coli: Comparison with purified native GM‐CSF (1986) (150)
Clonal analysis of progenitor cell commitment to granulocyte or macrophage production (1982) (148)
Point mutations within a dimer interface homology domain of c‐Mpl induce constitutive receptor activity and tumorigenicity. (1995) (146)
Structure and expression of the mRNA for murine granulocyte‐macrophage colony stimulating factor. (1985) (146)
THE PATTERN OF LYMPHOPOIESIS IN THE MOUSE THYMUS AFTER CORTISONE ADMINISTRATION OR ADRENALECTOMY. (1963) (146)
Binding of the differentiation-inducer, granulocyte-colony-stimulating factor, to responsive but not unresponsive leukemic cell lines. (1984) (145)
Identification, Purification, and Characterization of a Soluble Interleukin (IL)-13-binding Protein (1997) (144)
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner. (2014) (142)
Analysis of colonies developing in vitro from mouse bone marrow cells stimulated by kidney feeder layers or leukemic serum (1967) (142)
The colony stimulating factors discovery, development, and clinical applications (1990) (141)
Colony formation in vitro by myelomonocytic leukemic cells. (1969) (141)
Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors. (1980) (140)
Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor. (1997) (140)
The molecular control of blood cells (1988) (140)
Purification of a murine leukemia inhibitory factor from Krebs ascites cells. (1988) (137)
Purification and characterisation of the in vitro colony forming cell in monkey hemopoietic tissue (1972) (137)
A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. (1992) (135)
Noncycling state of peripheral blood progenitor cells mobilized by granulocyte colony-stimulating factor and other cytokines. (1995) (135)
In vitro colony formation by normal and leukemic human hematopoietic cells: interaction between colony-forming and colony-stimulating cells. (1973) (134)
The Rel subunit of NF‐kappaB‐like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations. (1996) (132)
Delayed Effect of Thymectomy in Adult Life on Immunological Competence (1965) (131)
Primary human myeloid leukemia cells: comparative responsiveness to proliferative stimulation by GM-CSF or G-CSF and membrane expression of CSF receptors. (1987) (131)
Osteoblasts display receptors for and responses to leukemia‐inhibitory factor (1990) (130)
Formation of eosinophilic‐like granulocytic colonies by mouse bone marrow cells in vitro (1974) (129)
Stimulation and Inhibition by Normal Human Serum of Colony Formation in Vitro by Bone Marrow Cells (1971) (129)
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance. (2010) (129)
The Colony-Stimulating Factors and Cancer (2013) (128)
Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity (1987) (127)
Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction (1999) (125)
The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells (2002) (124)
Thrombopoietin and hematopoietic stem cells (2011) (123)
Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity (2008) (123)
Studies on colony formation in vitro by mouse bone marrow cells . I. Continuous cluster formation and relation of clusters to colonies (1969) (122)
Production by spleen and lymph node cells of conditioned medium with erythroid and other hemopoietic colony‐stimulating activity (1978) (122)
Hemopoietic progenitor cells of W anemic mice studied in vivo and in vitro (1968) (121)
IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome. (2016) (120)
Leukemia inhibitory factor can potentiate murine megakaryocyte production in vitro. (1991) (118)
BCR – ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner (1998) (117)
Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: stimulation by endotoxin, M-CSF and multi-CSF. (1985) (116)
Resolution and purification of three distinct factors produced by Krebs ascites cells which have differentiation-inducing activity on murine myeloid leukemic cell lines. (1988) (116)
Bone Marrow Colony Stimulating Activity in Human Sera. RESULTS OF TWO INDEPENDENT SURVEYS IN BUFFALO AND MELBOURNE * (1968) (116)
Negative Regulation of Interleukin-12 Signaling by Suppressor of Cytokine Signaling-1* (2002) (114)
Regulation of granulocyte and monocyte-macrophage proliferation by colony stimulating factor (CSF): a review. (1973) (114)
Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors. (1991) (114)
Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation (2014) (114)
Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1) (2002) (113)
Critical role for granulocyte colony-stimulating factor in inflammatory arthritis. (2004) (113)
Cytogenetic analysis of human acute and chronic myeloid leukemic cells cloned in agar culture (1973) (112)
Heterogeneity of in vitro colony‐ and cluster‐forming cells in the mouse marrow: Segregation by velocity sedimentation (1975) (112)
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β (2015) (112)
Leukemia inhibitory factor--a puzzling polyfunctional regulator. (1992) (111)
Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. I. Isolation of pluripotent hemopoietic stem cells and granulocyte-macrophage progenitor cells (1980) (111)
Partial purification and some properties of the factor in normal and leukaemic human urine stimulating mouse bone marrow colony growth in vitro. (1969) (111)
Autoradiographic analysis of lymphocyte proliferation in the thymus and in thymic lymphoma tissue. (1966) (110)
Specific binding of murine leukemia inhibitory factor to normal and leukemic monocytic cells. (1988) (110)
The flt3/flk-2 ligand: receptor distribution and action on murine haemopoietic cell survival and proliferation. (1995) (109)
Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells. (1980) (108)
Colony stimulating factor and the regulation of granulopoiesis and macrophage production. (1975) (108)
The Effect of Thymectomy on the Lymphoid Tissues of the Mouse (1960) (107)
Clonal culture of hemopoietic cells: Techniques and applications (1984) (106)
Similar molecular properties of granulocyte-macrophage colony-stimulating factors produced by different mouse organs in vitro and in vivo. (1979) (105)
Stimulation of bone marrow colony growth in vitro by human urine. (1969) (104)
Nonneoplastic hematopoietic myeloproliferative syndrome induced by dysregulated multi-CSF (IL-3) expression. (1989) (104)
Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1 (2011) (102)
Induction of differentiation in HL60 leukaemic cells: a cell cycle dependent all-or-none event. (1984) (102)
Clonal analysis of the action of GM‐CSF on the proliferation and differentiation of myelomonocytic leukemic cells (1979) (102)
Clonal analysis of the actions of the murine leukemia inhibitory factor on leukemic and normal murine hemopoietic cells. (1988) (102)
Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy. (1998) (99)
The structure and expression of the murine gene encoding granulocyte‐macrophage colony stimulating factor: evidence for utilisation of alternative promoters. (1985) (98)
The Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses (2002) (98)
Leukemia inhibitory factor levels are elevated in septic shock and various inflammatory body fluids. (1992) (97)
Distribution and comparison of receptors for leukemia inhibitory factor on murine hemopoietic and hepatic cells (1991) (97)
Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia (2006) (97)
Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling. (2005) (97)
Autoinduction of differentiation in wehi‐3B leukemia cells (1982) (96)
Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy (2007) (95)
Biologic properties of molecularly cloned and expressed murine interleukin-3. (1985) (94)
AUTORADIOGRAPHIC ANALYSIS OF LYMPHOPOIESIS AND LYMPHOCYTE MIGRATION IN MICE BEARING MULTIPLE THYMUS GRAFTS (1966) (94)
Lymphoid tissue and plasmacytoid dendritic cells and macrophages do not share a common macrophage-dendritic cell-restricted progenitor. (2014) (93)
Actions and interactions of G-CSF, LIF, and IL-6 on normal and leukemic murine cells. (1989) (93)
Clonal extinction of myelomonocytic leukemic cells by serum from mice injected with endotoxin (1980) (92)
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage (2009) (92)
Production of Leukemia Inhibitory Factor in Escherichia coli by a Novel Procedure and Its Use in Maintaining Embryonic Stem Cells in Culture (1989) (90)
Production of monocyte/macrophage colony‐stimulating factor by preadipocyte cell lines derived from murine marrow stroma (1982) (90)
HAEMOPOIETIC GROWTH FACTORS 1 (1989) (90)
Role of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in the development of an acute neutrophil inflammatory response in mice. (1996) (89)
Local production of colony-stimulating factor within the bone marrow: role of nonhematopoietic cells. (1972) (88)
Suppressor of cytokine signaling-1 in T cells and macrophages is critical for preventing lethal inflammation. (2005) (88)
Isolation of murine fetal hemopoietic progenitor cells and selective fractionation of various erythroid precursors. (1981) (88)
Isolation and surface labeling of murine polymorphonuclear neutrophils (1979) (87)
Standardized bioassay for bone marrow colony stimulating factor in human urine: levels in normal man. (1972) (87)
Concise Review: Hematopoietic Stem Cells and Tissue Stem Cells: Current Concepts and Unanswered Questions (2007) (86)
Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis. (2015) (86)
Purification of two forms of colony-stimulating factor from mouse L-cell-conditioned medium. (1985) (84)
THE AUTONOMOUS BEHAVIOUR OF NORMAL THYMUS GRAFTS. (1963) (84)
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1 (1999) (84)
Heterogeneity in human neutrophil, macrophage and eosinophil progenitor cells demonstrated by velocity sedimentation separation. (1977) (83)
Stem Cells, Pre‐Progenitor Cells and Lineage‐Committed Cells: Are Our Dogmas Correct? (1999) (80)
Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice. (1989) (80)
Responsiveness of human granulocytic leukemic cells to colony-stimulating factor. (1974) (80)
Thrombopoietin — at last (1994) (80)
Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells (1989) (80)
Preparation of colony stimulating factors from human placental conditioned medium (1978) (79)
Growth of B lymphocyte colonies in vitro from mouse lymphoid organs (1975) (79)
Monocyte Production of Colony Stimulating Factor in Familial Cyclic Neutropenia (1974) (79)
Role of mercaptoethanol and endotoxin in stimulating B lymphocyte colony formation in vitro. (1976) (78)
Reticular Tumours in Mice Subjected to Prolonged Antigenic Stimulation (1961) (77)
Suckling defect in mice lacking the soluble haemopoietin receptor NR6 (1999) (77)
Membrane receptors of mouse leukocytes. II. Sequential expression of membrane receptors and phagocytic capacity during leukocyte differentiation (1978) (76)
Regulation of hematopoietic stem cells by their mature progeny (2010) (76)
Bone marrow colony-stimulating activity of serum from mice with viral-induced leukemia. (1967) (75)
THE THYMIC LYMPHOCYTOSIS‐STIMULATING FACTOR (1958) (75)
The detection and initial characterization of colony-stimulating factors in synovial fluid. (1988) (75)
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene (2006) (75)
Transformation of granulocytes to macrophages in bone marrow colonies in vitro (1971) (75)
Quantitative responsiveness of murine hemopoietic populations in vitro and in vivo to recombinant multi-CSF (IL-3). (1987) (74)
Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL. (1991) (74)
The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor. (2000) (73)
Colony formation by human T lymphocytes in agar medium. (1977) (73)
Binding of iodinated multipotential colony‐stimulating factor (interleukin‐3) to murine bone marrow cells (1986) (73)
SOCS5 Is Expressed in Primary B and T Lymphoid Cells but Is Dispensable for Lymphocyte Production and Function (2004) (73)
Measurement of ploidy distribution in megakaryocyte colonies obtained from culture: with studies of the effects of thrombocytopenia. (1981) (71)
Increased levels of leukemia inhibitory factor in synovial fluid from patients with rheumatoid arthritis and other inflammatory arthritides. (1993) (71)
Detection of a new type of mouse eosinophil colony by Luxol-fast-blue staining. (1980) (71)
Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. (2012) (71)
Studies on the bone marrow colony stimulating factor (CSF): Relation of tissue CSF to serum CSF (1972) (70)
A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation (2014) (70)
Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells (2008) (70)
Cytoplasmic domains of the common β‐chain of the GM‐CSF/IL‐3/IL‐5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines (1997) (70)
FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells. (2005) (69)
The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene. (2000) (69)
Effects of GM‐CSF deprivation on precursors of granulocytes and macrophages (1982) (69)
Development of hydrocephalus in mice lacking SOCS7. (2004) (69)
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways (2014) (68)
Behavior on Transfer of Serum Stimulated Bone Marrow Colonies.∗ (1967) (68)
Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome. (2010) (68)
Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene. (2005) (67)
Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production. (1998) (67)
The roles of stem cell self-renewal and autocrine growth factor production in the biology of myeloid leukemia. (1989) (67)
Cross-species comparison of the sequence of the leukaemia inhibitory factor gene and its protein. (1992) (67)
Clonal suppression of HL60 and U937 cells by recombinant human leukemia inhibitory factor in combination with GM-CSF or G-CSF. (1989) (67)
Broad inter‐individual variations in circulating progenitor cell numbers induced by granulocyte colony‐stimulating factor therapy (1995) (66)
Recombinant human leukemia inhibitory factor induces acute phase proteins and raises the blood platelet counts in nonhuman primates. (1993) (66)
Cellular processing of murine colony-stimulating factor (Multi-CSF, GM-CSF, G-CSF) receptors by normal hemopoietic cells and cell lines. (1988) (66)
Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells. (1996) (66)
Binding characteristics and proliferative action of purified granulocyte colony-stimulating factor (G-CSF) on normal and leukemic human promyelocytes. (1988) (65)
Differential expression of lectin receptors during hemopoietic differntiation: Enrichment for granulocyte‐macrophage progenitor cells (1980) (65)
THE GROWTH AND ERYTHROPOIETIC ACTIVITY OF SPLEEN GRAFTS PLACED UNDER THE KIDNEY CAPSULE. (1965) (65)
Leukemia inhibitory factor protects against experimental lethal Escherichia coli septic shock in mice. (1995) (65)
The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo. (2007) (65)
Colony-stimulating factor and inhibitor levels in acute granulocytic leukemia. (1971) (65)
Stem Cell Replacement in Normal Thymus Grafts.∗ (1964) (64)
A Novel Mutation in the Nfkb2 Gene Generates an NF-κB2 “Super Repressor”1 (2007) (64)
Purification of hemopoietic progenitor cells from human marrow using a fucose-binding lectin and cell sorting. (1980) (64)
Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s) (1982) (64)
Leukaemia inhibitory factor and interleukin 6 are expressed at very low levels in the normal adult mouse and are induced by inflammation. (1994) (64)
Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells. (1990) (63)
Quantitative studies on the stimulation of mouse bone marrow colony growth in vitro by normal human urine. (1969) (63)
MYC levels govern hematopoietic tumor type and latency in transgenic mice. (2006) (63)
The effects of acute thrombocytopenia on megakaryocyte-CFC and granulocyte-macrophage-CFC in mice: studies of bone marrow and spleen. (1980) (63)
Proliferation of normal human promyelocytes and myelocytes after a single pulse stimulation by purified GM-CSF or G-CSF. (1988) (61)
LIF: a molecule with divergent actions on myeloid leukaemic cells and embryonic stem cells. (1989) (61)
The Hemopoietic Colony-stimulating Factors: From Biology to Clinical Applications (1995) (61)
A myelosclerotic syndrome in mice engrafted with cells producing high levels of leukemia inhibitory factor (LIF). (1989) (61)
Biochemical properties of differentiation factors for murine myelomonocytic leukemic cells in organ conditioned media — separation from colony‐stimulating factors (1981) (61)
On hematopoietic stem cell fate. (2007) (60)
Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes (1985) (60)
Effect of recombinant human granulocyte‐macrophage colony stimulating factor on progenitor cells in patients with advanced malignancies (1990) (59)
Colony Production in vitro by Normal Polycythaemic and Anaemic Bone Marrow (1967) (59)
Receptors for C3 and IgG on macrophage, neutrophil and eosinophil colony cells grown in vitro. (1975) (58)
RESTRICTED GROWTH CAPACITY OF MULTIPLE SPLEEN GRAFTS (1964) (58)
Preparation and neutralization characteristics of an anti‐CSF antibody (1975) (58)
Clonal analysis of the response of HL60 human myeloid leukemia cells to biological regulators. (1983) (58)
Purification of a multipotential colony-stimulating factor from pokeweed mitogen-stimulated mouse spleen cell conditioned medium. (1985) (57)
Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection (2014) (56)
The colony-stimulating factors and cancer (2010) (56)
MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells. (2016) (56)
Enhanced suppression of human myeloid leukemic cell lines by combinations of IL‐6, LIF, GM‐CSF and G‐CSF (1990) (56)
Distinct Roles for Leukemia Inhibitory Factor Receptor α-Chain and gp130 in Cell Type-specific Signal Transduction* (1997) (56)
Agm1/Pgm3-Mediated Sugar Nucleotide Synthesis Is Essential for Hematopoiesis and Development (2007) (55)
The Effect of Bleeding on the Number of in Vitro Colony‐Forming Cells in the Bone Marrow (1969) (55)
Functional Analysis of Asb-1 Using Genetic Modification in Mice (2001) (54)
The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation. (1993) (54)
Adherence column and buoyant density separation of bone marrow stem cells and more differentiated cells (1971) (54)
The effect of colony stimulating factor on the synthesis of ribonucleic acid by mouse bone marrow cells in vitro (1977) (54)
Influence of the spleen and thymus on immune responses in ageing mice. (1967) (54)
The Wellcome Foundation Lecture, 1986 - The molecular control of normal and leukaemic granulocytes and macrophages (1987) (53)
IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3 (2011) (53)
Clearance and fate of leukemia‐inhibitory factor (LIF) after injection into mice (1991) (53)
Purification and partial amino acid sequence of asialo murine granulocyte-macrophage colony stimulating factor. (1985) (52)
Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease. (2005) (52)
Production of hematopoietic regulatory factors in cultures of adult and fetal mouse organs: measurement by specific bioassays. (1995) (52)
Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor. (1994) (52)
PAS-positive reticulum cells in the thymus cortex of high and low leukaemia strains of mice. (1962) (51)
Multi-CSF-dependent colony formation by cells of a murine hemopoietic cell line: specificity and action of multi-CSF (1985) (51)
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction (2020) (51)
Suppressor of Cytokine Signaling-1 Has IFN-γ-Independent Actions in T Cell Homeostasis1 (2003) (51)
Eosinophil colony formation in semisolid cultures of human bone marrow cells. (1977) (51)
Neutralization of interferon‐γ in neonatal SOCS1−/− mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease (2001) (51)
Production of colony-stimulating factor in mixed leucocyte cultures. (1974) (51)
Inter‐species chimeras of leukaemia inhibitory factor define a major human receptor‐binding determinant. (1993) (50)
Histologic and transplantation studies on preleukemic thymus of the AKR mouse. (1966) (50)
Selective up-regulation of macrophage function in granulocyte-macrophage colony-stimulating factor transgenic mice. (1991) (50)
Hematopoietic defects in the Ts1Cje mouse model of Down syndrome. (2009) (50)
Receptor clearance obscures the magnitude of granulocyte-macrophage colony-stimulating factor responses in mice to endotoxin or local infections. (1999) (49)
The clonal proliferation of normal mouse hematopoietic cells: enhancement and suppression by colony-stimulating factor combinations. (1992) (49)
Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. (2011) (49)
Architectural Defects in the Spleens of Nkx2-3-Deficient Mice Are Intrinsic and Associated with Defects in Both B Cell Maturation and T Cell-Dependent Immune Responses1 (2003) (49)
Mononuclear cell-mediated enhancement of granulocyte function in man. (1984) (48)
Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis (2013) (48)
Regulator‐induced suppression of myelomonocytic leukemic cells: Clonal analysis of early cellular events (1982) (48)
The Role of the Colony‐Stimulating Factors in Resistance to Acute Infections (1987) (46)
The Thymus: Its Role in Immune Responses, Leukaemia Development and Carcinogenesis (1966) (46)
Quantitative Cytological Studies on Thymic Lymphoid Cells in Normal, Preleukaemic and Leukaemic Mice (1961) (46)
Peritoneal cell population of mice infected with Mesocestoides corti as a source of eosinophils. (1979) (46)
Identification of the bone marrow colony mononuclear phagocyte as a macrophage. (1972) (46)
Stimulation by Leukaemic Sera of Colony Formation in Solid Agar Cultures by Proliferation of Mouse Bone Marrow Cells (1967) (46)
Eosinophil activation by colony-stimulating factor in man: metabolic effects and analysis by flow cytometry. (1983) (46)
Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. (2019) (45)
The excess numbers of peritoneal macrophages in granulocyte-macrophage colony-stimulating factor transgenic mice are generated by local proliferation (1992) (45)
The Molecular Weight of Colony-Stimulating Factor (CSF) (1971) (45)
Changes in hemopoietic and regulator levels in mice during fatal or nonfatal malarial infections. I. Erythropoietic populations. (1990) (45)
Neutrophils Require SHP1 To Regulate IL-1β Production and Prevent Inflammatory Skin Disease (2011) (45)
Conversion of the biological specificity of murine to human leukemia inhibitory factor by replacing 6 amino acid residues. (1994) (45)
LOCAL AND SYSTEMIC CONTROL OF GRANULOCYTIC AND MACROPHAGE PROGENITOR CELL REGENERATION AFTER IRRADIATION (1973) (44)
Changes in hemopoietic and regulator levels in mice during fatal or nonfatal malarial infections. II. Nonerythroid populations. (1990) (44)
Granulocyte colony-stimulating factor induces selective elevations of progenitor cells in the peripheral blood of mice. (1994) (44)
The presence of mast cells in agar cultures. (1980) (43)
Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia (2012) (43)
The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor α-Chain Is Determined Primarily by the Immunoglobulin-like Domain* (1997) (43)
Independent regulation of granulocyte-macrophage colony-stimulating factor and multi-lineage colony-stimulating factor production in T lymphocyte clones. (1986) (43)
HAEMOPOIETIC GROWTH FACTORS 2: CLINICAL APPLICATIONS (1989) (43)
Assessment of CD4 expression by early T precursor cells and by dendritic cells in the human thymus. (1994) (43)
Proliferation of macrophage and granulocyte precursors in response to primary and transplanted tumors. (1971) (42)
Cross-species receptor binding characteristics of human and mouse leukemia inhibitory factor suggest a complex binding interaction. (1994) (42)
Circulating leukemia inhibitory factor levels correlate with disease severity in meningococcemia. (1994) (42)
Induction of growth alterations in factor-dependent hematopoietic progenitor cell lines by cocultivation with irradiated bone marrow stromal cell lines. (1986) (42)
A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor". (2007) (41)
Progenitor cell mobilization by granulocyte colony-stimulating factor controlled by loci on chromosomes 2 and 11. (2000) (41)
Immune responses in preleukaemic and leukaemic AKR mice (1967) (41)
Adrenal cortical function in high- and low-leukemia strains of mice. (1960) (41)
The serum factor stimulating colony formation in vitro by murine plasmacytoma cells: response to antigens and mineral oil. (1974) (40)
Colony stimulating activity of serum from germfree normal and leukemic mice (1967) (40)
Cellular hematopoiesis in the twentieth century. (1999) (40)
Bone Marrow Colony-stimulating Activity of Sera in Infectious Mononucleosis (1968) (40)
Normal Human Bone Marrow Cultures in Vitro: Cellular Composition and Maturation of the Granulocytic Colonies (1977) (40)
Effect of Thymidine Suiciding on Colony Formation in Vitro by Mouse Hematopoietic Cells 1 (1972) (39)
Fatal polycythemia induced in mice by dysregulated erythropoietin production by hematopoietic cells. (1992) (39)
Separate actions of different colony stimulating factors from human placental conditioned medium on human hemopoietic progenitor cell survival and proliferation (1981) (39)
T lymphocyte-derived colony-stimulating factors. (1990) (39)
Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice. (2008) (38)
Synergistic and Inhibitory Interactions in the In Vitro Control of Murine Megakaryocyte Colony Formation (2002) (38)
Inhibition by mouse serum of hemopoietic colony formation in vitro. (1976) (38)
Multiplication and Division in Mammalian Cells (1977) (37)
Inhibition of Bone Marrow Colony Formation by Normal and Leukaemic Human Serum (1970) (37)
Cellular and molecular basis of the increased splenic hemopoiesis in mice treated with bacterial cell wall components. (1980) (37)
Enzyme treatment of colony stimulating factor: evidence for a peptide component. (1971) (37)
Divergent disease patterns in granulocyte-macrophage colony-stimulating factor transgenic mice associated with different transgene insertion sites. (1988) (37)
The role of the thymus in the ontogeny of the immune system (1966) (36)
The colony stimulating factor (CSF). (1972) (36)
T-cell hybridoma secreting hemopoietic regulatory molecules: Granulocyte-macrophage and eosinophil colony-stimulating factors (1979) (36)
A model system for leukemic transformation of immortalized hemopoietic cells in irradiated recipient mice. (1988) (36)
Detection and analysis of human granulocyte--monocyte precursors using semi-solid cultures. (1979) (36)
Antigen-induced proliferation in vitro of bone marrow precursors of granulocytes and macrophages. (1971) (36)
Negative regulation of cytokine signaling by the SOCS proteins. (1999) (36)
A Lymphocytosis Stimulating Factor in the Plasma of Chronic Lymphatic Leukaemic Patients (1956) (36)
Vaginally Administered PEGylated LIF Antagonist Blocked Embryo Implantation and Eliminated Non-Target Effects on Bone in Mice (2011) (36)
The Florey Lecture, 1991. The colony-stimulating factors: discovery to clinical use. (1991) (35)
Binding, internalization, and degradation of 125I-multipotential colony-stimulating factor (interleukin-3) by FDCP-1 cells. (1988) (35)
Nature of cells forming erythroid colonies in agar after stimulation by spleen conditioned medium (1978) (35)
Isolation of mouse bone marrow neutrophils by light scatter and autofluorescence. (1980) (35)
Interleukin-4 is chemotactic for mouse macrophages. (1992) (35)
THE NATURE OF LEUKAEMIA: NEOPLASM OR DISORDER OF HAEMOPOIETIC REGULATION?1 (1971) (34)
SCL, the gene implicated in human T-cell leukaemia, is oncogenic in a murine T-lymphocyte cell line. (1993) (34)
Sources and biology of regulatory factors active on mouse myeloid leukeimic cells (1982) (33)
The regulatory factors controlling murine erythropoiesis in vitro. (1984) (33)
Human leukaemia: recent tissue culture studies on the nature of myeloid leukaemia. (1973) (33)
Interactions between purified GM‐CSF, purified erythropoietin and spleen conditioned medium on hempoietic colony formation in vitro (1979) (33)
The behaviour of thymus grafts in high and low leukaemia strains of mice. (1961) (33)
Fractionated populations of normal human marrow cells respond to both human colony-stimulating factors with granulocyte-macrophage activity. (1985) (33)
Differential alterations in plasma colony‐stimulating factor concentrations in meningococcaemia (1995) (33)
Characterization of thrombopoietin (TPO)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential (2012) (33)
Further studies on the factor in lung‐conditioned medium stimulating granulocyte and monocyte colony formation in vitro (1974) (32)
The nature of the cells generating B‐Lymphocyte colonies in vitro (1976) (32)
Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. II. Isolation of terminal deoxynucleotidyl transferase-positive cells (1980) (32)
Murine hematopoietic stem cells committed to macrophage/dendritic cell formation: stimulation by Flk2-ligand with enhancement by regulators using the gp130 receptor chain. (1997) (32)
Analysis of hematopoiesis in max 41 transgenic mice that exhibit sustained elevations of blood granulocytes and monocytes. (1995) (32)
Production of hemopoietic stimulating factors by pokeweed-mitogen-stimulated spleen cells. (1978) (31)
Effects of irradiation of recipient mice on the behavior and leukemogenic potential of factor-dependent hematopoietic cell lines. (1990) (31)
Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation. (2008) (31)
INDUCTION OF BONE MARROW COLONY-STIMULATING ACTIVITY BY A FILTERABLE AGENT IN LEUKEMIC AND NORMAL MOUSE SERUM (1968) (31)
Tissue localization and fate in mice of injected multipotential colony-stimulating factor. (1988) (31)
THE FATE OF PARENTAL PRELEUKEMIC CELLS IN LEUKEMIA-SUSCEPTIBLE AND LEUKEMIA-RESISTANT F1 HYBRID MICE. (1963) (30)
Migration of Cells to the Thymus Demonstrated by Parabiosis.∗ (1967) (30)
Lectin receptors on human blood and bone marrow cells and their use in cell separation. (1980) (30)
Stimulation by human urine or plasma of granulopoiesis by human marrow cells in agar. (1974) (30)
Potentiation of bone marrow colony growth in vitro by the addition of lymphoid or bone marrow cells (1968) (30)
Structural characterization of a murine myeloid leukaemia inhibitory factor. (1988) (30)
Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling* (2004) (30)
Serum potentiation of granulocyte and macrophage colony formation in vitro. (1975) (30)
Factors modifying stem cell proliferation of myelomonocytic leukemic cells in vitro and in vivo. (1970) (29)
Eosinophil and neutrophil colony-forming cells in culture. (1977) (29)
Serum half-life and organ distribution of radiolabeled colony stimulating factor in mice. (1977) (29)
Inhibition of bone marrow colony formation in vitro by dialysable products of normal and neoplastic haemopoietic cells. (1971) (29)
Molecular control of granulocyte and macrophage production. (1985) (29)
Studies of the c‐Mpl Thrombopoietin Receptor through Gene Disruption and Activation (1996) (29)
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice (2010) (29)
Effect of Whole Body Irradiation on Colony Production by Bone Marrow Cells in vitro∗ (1967) (28)
Development of B-lymphocyte colony-forming cells in foetal mouse tissues. (1976) (28)
IL-5 and Rp105 signaling defects in B cells from commonly used 129 mouse substrains. (1999) (28)
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a (2016) (28)
Identification, Purification, and Characterization of a Soluble Interleukin (IL)-13-binding Protein EVIDENCE THAT IT IS DISTINCT FROM THE CLONED IL-13 RECEPTOR AND IL-4 RECEPTOR a-CHAINS* (1997) (28)
Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis. (2003) (27)
Early Lineage Priming by Trisomy of Erg Leads to Myeloproliferation in a Down Syndrome Model (2015) (27)
In-vitro cloning techniques for hemopoietic cells: clinical applications. (1977) (27)
Characteristics of colony-stimulating factor production by murine T-lymphocyte clones. (1985) (27)
A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia (2006) (26)
SOCS 2 negatively regulates growth hormone action in vitro and in vivo (2005) (26)
Selective stimulation by mouse spleen cell conditioned medium of human eosinophil colony formation. (1983) (26)
Multiple Thymus Grafts in Aged Mice (1965) (26)
Periodic Acid–Schiff Positive Giant Cells in the Mouse Thymus Cortex (1961) (26)
Mutagenesis of murine granulocyte/macrophage-colony-stimulating factor reveals critical residues near the N terminus. (1987) (26)
The clonal proliferation in vitro of enriched populations of human promyelocytes and myelocytes. (1985) (25)
Density gradient segregation of bone marrow cells with the capacity to form granulocytic and macrophage colonies in vitro. (1971) (25)
Specificity of action of colony-stimulating factors in the differentiation of granulocytes and macrophages. (1986) (24)
INFLUENCE OF AGE AND ANTIGENIC STIMULATION ON GRANULOCYTE AND MACROPHAGE PROGENITOR CELLS IN THE MOUSE SPLEEN (1972) (24)
Alkaline phosphatase activity in mouse lymphoma tissue. (1962) (24)
The cellular basis for enhancement interactions between stem cell factor and the colony stimulating factors (1993) (24)
The in vitro behavior of hemopoietic cells transformed by polyoma middle T antigen parallels that of primary human myeloid leukemic cells. (1987) (23)
Separation of hemopoietic cells from adult mouse marrow by use of monoclonal antibodies. (1983) (23)
Colony formation in agar by murine plasmacytoma cells: Potentiation by hemopoietic cells and serum (1973) (23)
Plasminogen activator in granulocyte-macrophage-CSF transgenic mice. (1992) (23)
Spleen graft growth in splenectomised mice. (1963) (23)
Cells in Culture (1977) (23)
Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia (2013) (23)
Formation in agar of fibroblast‐like colonies by cells from the mouse pleural cavity and other sources (1972) (23)
Granulocyte/macrophage colony-stimulating factor from mouse lung conditioned medium. Purification of multiple forms and radioiodination. (1986) (23)
Neutralizing and nonneutralizing monoclonal antibodies to the human granulocyte-macrophage colony-stimulating factor receptor alpha-chain. (1993) (22)
Regulatory mechanisms controlling hematopoiesis: Principles and problems (1998) (22)
Analysis of purified fetal liver hemopoietic progenitor cells in liquid culture (1982) (22)
Effects of excess GM-CSF levels on hematopoiesis and leukemia development in GM-CSF/max 41 double transgenic mice. (1996) (21)
Stem Cell Factor Can Stimulate the Formation of Eosinophils by Two Types of Murine Eosinophil Progenitor Cells (2002) (21)
Elevated levels of GM-CSF and IL-1 in the serum, peritoneal and pleural cavities of GM-CSF transgenic mice. (1989) (21)
Transgenic expression of GM-CSF in T cells causes disseminated histiocytosis. (2014) (21)
Synergistic suppression: anomalous inhibition of the proliferation of factor-dependent hemopoietic cells by combination of two colony-stimulating factors. (1992) (21)
The hemopoietic regulators – an embarrassment of riches (1992) (21)
Actions of leukaemia inhibitory factor on megakaryocyte and platelet formation. (1992) (21)
Colony-Stimulating Factor and the Differentiation of Granulocytes and Macrophages (1977) (21)
Lineage commitment in the progeny of murine hematopoietic preprogenitor cells: influence of thrombopoietin and interleukin 5. (1998) (21)
The colony-stimulating factors and myeloid leukaemia. (1985) (21)
The structural basis of the biological actions of the GM-CSF receptor. (1997) (21)
A Kinase-Dead Allele of Lyn Attenuates Autoimmune Disease Normally Associated with Lyn Deficiency1 (2009) (21)
Further Studies on the Plasma Lymphocytosis Stimulating Factor in Chronic Lymphatic Leukaemia and some other Disease States (1956) (20)
Nomenclature for secreted regulatory proteins of the immune system (interleukins) (1992) (20)
GM-CSF produced by recombinant vaccinia virus or in GM-CSF transgenic mice has no effect in vivo on murine cutaneous leishmaniasis. (1988) (20)
Production of Colony Stimulating Factors by Lymphoid Tissues (1979) (20)
Functional interactions between the thymus and other organs. (1964) (20)
The lethal effects of transplantation of Socs1-/- bone marrow cells into irradiated adult syngeneic recipients (2003) (20)
Haemopoietic growth factors (1988) (20)
Identification of a genetic locus modulating splenomegaly induced by granulocyte colony-stimulating factor in mice (2000) (19)
Distribution and binding properties of receptors for leukaemia inhibitory factor. (1992) (19)
INDUCTION OF RETICULAR TUMOURS IN MICE BY REPEATED ANTIGENIC STIMULATION. (1963) (19)
Humoral regulation of splenic hemopoiesis in mice. (1980) (19)
The Molecular Control of Hematopoiesis: Progress and Problems with Gene Manipulation (1998) (19)
Granulocyte-macrophage colony-stimulating factor produced by an inducible murine T-cell hybridoma: molecular properties and cellular specificity. (1981) (19)
Fms-like tyrosine kinase 3 catalytic domain can transduce a proliferative signal in FDC-P1 cells that is qualitatively similar to the signal delivered by c-Fms. (1994) (19)
Separation of mouse bone marrow cells using wheat germ agglutinin affinity chromatographyy. (1978) (19)
Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells (2016) (18)
Relation of the Thymus to the Formation of Immunologically Reactive Cells (1967) (18)
The SOCS-1 story. (1999) (18)
Sources and nature of granulocyte-macrophage colony stimulating factor in fetal mice. (1978) (18)
Murine erythroid cell lines derived with c-myc retroviruses respond to leukemia-inhibitory factor, erythropoietin, and interleukin 3. (1991) (18)
The molecular control of granulocytes and macrophages. (1997) (18)
Hhex Regulates Hematopoietic Stem Cell Self‐Renewal and Stress Hematopoiesis via Repression of Cdkn2a (2017) (18)
Biochemical and functional characterization of mature progeny purified from a myelomonocytic leukemia cell line. (1982) (18)
The effects of leukaemia inhibitory factor on platelet function (1993) (18)
The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF (1998) (18)
Humoral regulators in the development and progression of leukemia. (1971) (17)
Regulation of macrophage production. (1982) (17)
Receptor insertion into factor-dependent murine cell lines to develop specific bioassays for murine G-CSF and M-CSF and human GM-CSF. (1994) (17)
Blimp1 is limiting for transformation in a mouse plasmacytoma model. (2009) (17)
Regulation of hemopoietic cell differentiation and proliferation. (1978) (16)
Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells (2013) (16)
Techniques for the Clonal Culture of Hemopoietic Cells in Semisolid Medium (1977) (16)
Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation (1999) (16)
Hemopoietic effects of purified bacterially synthesized multi-CSF in normal and marrow-transplanted mice. (1986) (16)
Coulter counter analysis of lymphoma differentiation patterns in AKR mice with lymphoid leukaemia (1967) (16)
Migration of cells to the thymus demonstrated by parabiosis. (1967) (16)
Two distinct types of murine blast colony-forming cells are multipotential hematopoietic precursors (2008) (16)
Development of dendritic cells in culture from human and murine thymic precursor cells. (2001) (16)
Induction of differentiation in murine myelomonocytic leukemia cells by the serum of patients with acute myeloid leukemia and other diseases (1981) (16)
Activation and proliferation signals in murine macrophages: synergistic interactions between the hematopoietic growth factors and with phorbol ester for DNA synthesis (1988) (16)
THE GROWTH AND REPOPULATION OF THYMUS GRAFTS PLACED UNDER THE KIDNEY CAPSULE. (1965) (16)
The granulocyte-macrophage regulators: reappraisal by gene inactivation. (1995) (16)
The Multipotential Colony-Stimulating Factor, Multi-CSF (IL-3) (1988) (16)
The proliferative effects of human GM-CSFα and β and murine G-CSF in microwell cultures of fractionated human marrow cells (1985) (15)
Hemopoietic regulators. (1992) (15)
HOST-CELL REPOPULATION OF NORMAL SPLEEN GRAFTS. (1964) (15)
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion. (2018) (15)
HAEMOPOIETIC GROWTH FACTORS NOW CLONED (1986) (15)
Purification of Mouse Lung-Conditioned Medium Colony Stimulating Factor (CSF) 1 (1974) (15)
Production of Colony-Stimulating Factors and IL-5 by Organs from Three Types of Mice with Inflammatory Disease Due to Loss of the Suppressor of Cytokine Signaling-11 (2001) (15)
Anti-bacterial activity of peritoneal cells from transgenic mice producing high levels of GM-CSF. (1990) (15)
Surface antigens on normal and leukaemic human cells detected by monoclonal antibodies. (2009) (15)
Multipotential hematopoietic blast colony-forming cells exhibit delays in self-generation and lineage commitment (2010) (15)
Genetic Deletion of Murine SPRY Domain-Containing SOCS Box Protein 2 (SSB-2) Results in Very Mild Thrombocytopenia (2005) (14)
The molecular control of proliferation and differentiation in hemopoietic cells. (1993) (14)
Erratum: Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo (Nature Immunology (2007) 10.1038/ni1522) (2007) (14)
Cell–cell signalling in the regulation of blood cell formation and function (1998) (14)
Serum Half Life in Mice of Colony Stimulating Factor Prepared from Human Urine (1971) (14)
Cellular differentiation in a murine myelomonocytic leukemia. (1972) (14)
Activation and proliferation signals in murine macrophages: synergistic interactions between the hematopoietic growth factors and with phorbol ester for DNA synthesis. (1988) (14)
Suppressor of Cytokine Signaling-1 Has IFN- -Independent Actions in T Cell Homeostasis (2002) (14)
Endotoxin‐induced size change in bone marrow progenitors of granulocytes and macrophages (1976) (14)
Regulation of hemopoiesis. (1979) (14)
Multi-CSF-dependent colony formation by cells of a murine hemopoietic cell line: specificity and action of multi-CSF. (1985) (13)
The Structure of the Thymus (1966) (13)
Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia (2006) (13)
Mechanisms contributing to the sex difference in levels of granulocyte-macrophage colony-stimulating factor in the urine of GM-CSF transgenic mice. (1988) (13)
The origin of mitotic cells in normal thymus grafts. (1963) (13)
Murine flt3 ligand protects M1 leukemic cells from LIF-induced differentiation and suppression of self-renewal. (1996) (13)
The Box-1 Region of the Leukemia Inhibitory Factor Receptor α-Chain Cytoplasmic Domain Is Sufficient for Hemopoietic Cell Proliferation and Differentiation* (1998) (13)
Implications of the polyfunctionality of hemopoietic regulators (1994) (13)
Differentiation commitment and regulator-specific granulocyte–macrophage maturation in a novel pro-B murine leukemic cell line (2000) (13)
The production of vaccinia haemagglutinin by the chorioallantoic membrane of embryonated eggs. (1955) (13)
THE CONSEQUENCES OF EXCESS LEVELS OF HAEMOPOIETIC GROWTH FACTORS (1990) (12)
The Control of Neutrophil and Macrophage Production at the Progenitor Cell Level (1978) (12)
A model of haemopoietic cell colony formation. (1972) (12)
Segregation of mouse hemopoietic progenitor cells using the monoclonal antibody, YBM/42 (1983) (12)
B lymphocyte colony-forming cells in the SJL/J mouse. (1977) (12)
The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal. (2021) (12)
Pre-progenitor cells: a proposed new category of hematopoietic precursor cells (1998) (12)
Clonogenic mast cell progenitors and their excess numbers in chimeric BALB/c mice with inactivated GATA-1 (2007) (12)
Peptide regulatory factors. Haemopoietic growth factors 1 (1989) (12)
MOZ and BMI1 act synergistically to maintain hematopoietic stem cells. (2017) (12)
Cytotoxicity in vitro of preleukaemic lymphoid cells on syngeneic monolayers of embryo or thymus cells. (1970) (11)
The induction and inhibition of differentiation in normal and leukaemic cells. (1990) (11)
Radiation-induced enlargement of granulocytic and macrophage progenitor cells in mouse bone marrow. (1977) (11)
Depressed responses of the granulocyte-macrophage system to bacterial antigens following preimmunization. (1974) (11)
Hemopoietic regulators and leukemia development: a personal retrospective. (1994) (11)
THYMUS GRAFTS AND LEUKEMOGENESIS. (1964) (10)
Overexpression of C-FMS in the myeloid cell line FDC-P1 induces transformation that dissociates M-CSF-induced proliferation and differentiation. (1995) (10)
Leukemic cells from murine myeloid leukemia display an intrinsic ability for autonomous proliferation. (2000) (10)
Distribution of IL-6 receptors on murine hemopoietic and lymphoid cells and the anomalous action of IL-6 in stimulating granulocytic proliferation. (1994) (10)
Hematopoietic stem cells: old and new. (2001) (10)
A convenient method for preparation of an engineered mouse interleukin-3 analog with high solubility and wild-type bioactivity (2010) (10)
Leukemic transformation of immortalized FDC-P1 cells engrafted in GM-CSF transgenic mice. (1993) (10)
Murine hematopoietic blast colony-forming cells and their progeny have distinctive membrane marker profiles (2009) (10)
Growth and responsiveness of human granulocytic leukemic cells in vitro. (1975) (10)
The multi-organ origin of interleukin-5 in the mouse (2001) (9)
Report of a workshop on standardization of selective cultures for normal and leukaemic cells. (1977) (9)
Proliferation and behavior of phagocytic cells in mouse lymphoma tissue. (1967) (9)
The Charlotte Friend Memorial Lecture. The role of hematopoietic growth factors in the development and suppression of myeloid leukemias (1997) (9)
Lymphocytosis Response in Mice and Its Relation to Thymus and Adrenal.∗ (1957) (9)
Use of spleen organ cultures to monitor hemopoietic progenitor cell regeneration following irradiation and marrow transplantation (1980) (9)
How does gamma-interferon mediate resistance to Listeria monocytogenes? (1994) (9)
Characterization of mouse fetal liver granulocyte-macrophage colony-forming cells using velocity sedimentation. (1978) (8)
The cytokine receptor repertoire specifies autocrine growth factor production in factor-dependent cells. (1995) (8)
Regulatory control of the proliferation ad differentiation of normal and leukemia cells. (1982) (8)
The preleukemic state of mice reconstituted with Mixl1-transduced marrow cells (2007) (8)
Colony stimulating factors and hemopoiesis. (1988) (8)
Two cases of carcinoma of the lung characterized by a bone marrow agar culture pattern resembling acute myeloid leukemia. (1979) (8)
Growth of factor-dependent haematopoietic cell lines (1981) (8)
156 A Novel Mutation in the Nfkb2 Gene Generates an NFκB2 ‘Super Repressor’ (2007) (8)
Reduced Lymphocyte Longevity and Homeostatic Proliferation in Lamin B Receptor-Deficient Mice Results in Profound and Progressive Lymphopenia (2012) (8)
Role of the colony stimulating factors in the emergence and suppression of myeloid leukemia populations (1985) (8)
The Hemopoietic Colony-Stimulating Factors: Biological actions of the colony-stimulating factors in vitro (1995) (7)
The Bone Marrow Colony Stimulating Factor (CSF): Relation of Serum CSF to Urine CSF 1 (1973) (7)
Establishment of multipotential and antigen presenting cell lines derived from myeloid leukemias in GM-CSF transgenic mice (1997) (7)
Factors influencing the time and site of leukemic transformation of factor‐dependent cells after injection into irradiated recipient mice (1989) (7)
Summon up the Blood: In dogged pursuit of the blood cell regulators (2000) (7)
PGM-1: a transplantable murine leukemia of granulocyte-macrophage progenitor cells. (1989) (7)
Differential seeding of injected hemopoietic precursor cells in the bone marrow and spleen of irradiated mice. (1980) (7)
Use of spleen organ cultures to monitor hemopoietic progenitor cell regeneration following irradiation and marrow transplantation. (1980) (7)
Selective isolation of murine erythropoietin-responsive progenitor cells (CFU-E) with monoclonal antibodies. (1983) (7)
Characteristics of in vitro colony formation by cells from haemopoietic tissues (2007) (7)
How Many Cancers are Reversible or Suppressible? (1983) (7)
Hemopoietic growth factors and marrow transplantation: an overview. (1989) (7)
Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation (2015) (7)
The Charlotte Friend Memorial Lecture. The role of hematopoietic growth factors in the development and suppression of myeloid leukemias (1999) (7)
The proliferative effects of human GM-CSF alpha and beta and murine G-CSF in microwell cultures of fractionated human marrow cells. (1985) (6)
Analysis of the role of the thymus in leukemia development with the use of thymectomy and thymus grafts. (1966) (6)
Mechanisms responsible for size differences between hemopoietic colonies: an analysis using a CSF-dependent hemopoietic cell line. (1992) (6)
Neutrophil and Macrophage Colony Formation by Normal Cells (1977) (6)
THE THYMUS AND ITS ROLE IN IMMUNITY AND CARCINOGENESIS (1965) (6)
The discrimination of leukemic from normal cells. (1973) (6)
Suppression or overexpression of genes encoding myeloid growth factors or their receptors. (1997) (6)
PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK 1-and RIPK 3-dependent manner (2014) (6)
The Hemopoietic Colony-Stimulating Factors: The biology of colony-stimulating factor production, degradation, and clearance (1995) (6)
Clinical applications of the agar culture technique for haemopoietic cells. (1971) (6)
Chromosomal and growth factor abnormalities in leukemia. AACR special conference in cancer research. (1991) (5)
The Thymus and Lymphoid Leukaemia (1966) (5)
The regulation of hematopoiesis in max 41 transgenic mice with sustained excess granulopoiesis. (1996) (5)
A promising new treatment for refractory aplastic anemia. (2012) (5)
The 1993 Burnet Lecture. The colony stimulating factors--discovery to clinical use. (1994) (5)
5 – THE COLONY STIMULATING FACTOR (CSF) (1973) (5)
Biochemical characterization of murine leukaemia inhibitory factor produced by Krebs ascites and by yeast cells. (1988) (5)
Eosinophil Colony Formation (1977) (5)
Control of hemopoietic cell proliferation and differentiation. (1981) (5)
PATTERNS OF CELLULAR DIFFERENTIATION IN SPONTANEOUS AND TRANSPLANTED LYMPHOMATA IN MICE. (1965) (5)
Another way to generate T cells? (1997) (5)
Pseudoneoplastic Nonspecific Proliferative Lesions on the Chorioallantois of the Chick Embryo (1955) (5)
Biological and biochemical properties of a serum factor that stimulates splenic hemopoiesis in mice. (1984) (5)
Erythroid Colony Formation (1977) (5)
Role of hemopoietic growth factors in the development and suppression of myeloid leukemia. (1992) (4)
Differentiation commitment in normal hemopoiesis and leukemic transformation (1997) (4)
5 – Granulocyte–Macrophage Colony-Stimulating Factors (1987) (4)
Aberrant G-CSF- and IL-6-Induced Proliferation and Differentiation in Suppressor of Cytokine Signaling-3 (SOCS3)-Deficient Progenitor Cells. (2004) (4)
The Hemopoietic Colony-Stimulating Factors: Actions of the colony-stimulating factors in resistance to infections (1995) (4)
Missense mutations in the MLKL ‘brace’ region lead to lethal neonatal inflammation in mice and are present in high frequency in humans (2019) (4)
Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain (2011) (4)
An Outline of Hemopoiesis and Current Terminology (1977) (4)
Stimulation of B-lymphocyte colony formation in vitro by sera from patients with leukaemia or lymphoma. (1976) (4)
The Hemopoietic Colony-Stimulating Factors: Historical introduction (1995) (4)
Haemopoiesis: A practical approach: edited by N.G. Testa and G. Molineau, The Practical Approach Series, IRL Press. Oxford University Press, 1993. £32.50/$59.00 (xxv + 293 pages) ISBN 019 963 3665 (1994) (4)
The regulatory control of hemopoietic populations. (1990) (4)
AGM: maternity ward or finishing school? (2008) (4)
Transplantation Bioassay of Thymuses from Preleukaemic AKR Mice for the Presence of Leukaemic Cells (1961) (4)
New type of colony-forming cell located in the pleural cavity. (1972) (4)
The Hemopoietic Colony-Stimulating Factors: Conclusions (1995) (4)
Loss of PU.1: One of the Many Roads to Myeloid Leukemia (2006) (4)
Lineage Commitment and Maturation Induction in Normal and Leukemic Preprogenitor Cells (2001) (3)
The clonal culture in vitro of multipotential hemopoietic cells: problems and interpretations. (1981) (3)
Bone Marrow in Hypoxia and Rebound (1976) (3)
Murine Megakaryocyte Progenitor Cells and Their Susceptibility to Suppression by G‐CSF (2005) (3)
Growth and Differentiation Factors. (2016) (3)
Development of a vaginally applied, non-hormonal contraceptive: the contraceptive efficacy and impact on bone turnover of PEGLA, a long-acting LIF antagonist (2010) (3)
Crowding-dependent production of colony-stimulating factors by cultured syngeneic or allogeneic hematopoietic cells (2003) (3)
The Colony Stimulating Factors: Discovery to Clinical Applications (1989) (3)
Bone marrow cells from A/J mice do not proliferate in interleukin‐3 but express normal numbers of interleukin‐3 receptors (1992) (3)
The thymic lymphocytosisstimulating factor. (1958) (3)
Disease states induced by hemopoietic growth factor excess: their implications in medicine. (1990) (3)
Approaches to some unanswered problems concerning aplastic anemia. (1978) (3)
How reliable are in vitro clonal cultures? Some comments based on hemopoietic cultures. (1986) (3)
Early events in the suppression of myeloid leukemic cells by biological regulators. (1983) (3)
In vitro cloning of hemopoietic cells. (1978) (3)
Cloning and expression of the gene for murine granulocyte-macrophage colony-stimulating factor. (1985) (3)
Molecular properties of a factor inducing differentiation in murine myelomonocytic leukemic cells. (1983) (3)
EFFECT OF PREGNANCY AND TESTOSTERONE ON THYMUS GRAFTS. (1964) (3)
Activation of human and murine B cells by anti-immunoglobulin antibody: dependence of the response on the preexisting level of B-cell activation. (1984) (2)
Initiation of immune responses against cancer cells (1972) (2)
Comments on editorial by G. Brown and co-workers: Stochastic or ordered lineage commitment during hemopoiesis? (1987) (2)
Hemopoietic growth factors and oncogenes in myeloid leukemia development. (1987) (2)
Spleen graft mast cell population changes following splenectomy of the host. (1965) (2)
The Nature and Regulation of Lymphopoiesis in the Normal and Neoplastic Thymus (2008) (2)
Reversible growth factor dependency and autonomy during murine myelomonocytic leukemia induced by oncogenes (2013) (2)
In Vitro Colony-Forming Cells in the Bone Marrow of Germfree Mice (1969) (2)
Regulation of Thymic Lymphopoiesis (1966) (2)
The Bcl-2 Protein Family Is Essential for Platelet Survival In Vivo. (2006) (2)
A Thymus Responsive Phase in Leukæmogenesis in AKR Mice (1962) (2)
Colony Formation by Myeloid Leukemic Cells (1977) (2)
Abnormal regulation of granulopoiesis in human acute granulocytic leukemia. (1973) (2)
Analysis of the leukemogenic properties of the bcr-v-abl and GM-CSF genes using a new retroviral vector. (1989) (2)
The Hemopoietic Colony-Stimulating Factors: Actions of the colony-stimulating factors in vivo (1995) (1)
Tissue Specific Stem Cells - The Lesson from Hematopoietic Stem Cell Transplantation (2008) (1)
Hemopoietic growth factor gene transfer. (1989) (1)
Suppressor of Cytokine Signaling-3 (SOCS3) Selectively Modulates Progenitor Cell Proliferation and Differentiation Induced by G-CSF and IL-6, and the Synergy between SCF and IL-6. (2006) (1)
General Features of Hemopoietic Colony Formation (1977) (1)
Haemopoietic growth factors I (1992) (1)
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction (2020) (1)
152. DEVELOPMENT OF A VAGINALLY APPLIED, NON-HORMONAL CONTRACEPTIVE: THE CONTRACEPTIVE EFFICACY AND IMPACT ON BONE TURNOVER OF PEGLA, A LONG-ACTING LIF ANTAGONIST (2010) (1)
The Hemopoietic Colony-Stimulating Factors: Biochemistry of the colony-stimulating factors (1995) (1)
Hemopoietic Stromal Colonies (1977) (1)
Correction: A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation (2014) (1)
and impaired neutrophil mobilization neutropenia, granulocyte and macrophage progenitor cell deficiency, Mice lacking granulocyte colony-stimulating factor have chronic (2011) (1)
Regulation of Growth and Differentiation in Haemopoietic Colonies Growing in Agar (2008) (1)
[Characterization of megakaryocyte colonies in vitro]. (1975) (1)
The molecular control of hematopoiesis: Progress and problems with gene manipulation (1998) (1)
The Hemopoietic Colony-Stimulating Factors: General introduction to hemopoiesis (1995) (1)
Key techniques in analyzing hemopoiesis (1995) (1)
hematopoietic progenitor cells in cancer patients Effects of recombinant human granulocyte colony-stimulating factor on (2011) (1)
Megakaryocytes Possess a Functional Intrinsic Apoptosis Pathway That Must Be Restrained In Order to Survive and Produce Platelets (2010) (1)
Potentiation of erythroid colony formation in fetal liver cultures containing serum from patients with hemochromatosis or acute myeloid leukemia. (1979) (1)
The Hemopoietic Colony-Stimulating Factors: Clinical uses of the colony-stimulating factors (1995) (1)
Erratum: A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation (The Journal of Immunology (2014) 193 (1766-1777)) (2014) (1)
RAPID COMMUNICATION Deficiencies in Progenitor Cells of Multiple Hematopoietic Lineages and Defective Megakaryocytopoiesis in Mice Lacking the Thrombopoietin Receptor c-Mpl (2002) (1)
Characteristics of B-lymphocyte colony growth in vitro. (1976) (1)
The aetiology and pathogenesis of leukaemia. (1962) (1)
The Biology of Cancer: A New Approach (1976) (1)
Leukaemia strains of mice. (1962) (1)
The Thymus and Immune Responses (1966) (1)
Effect of the Thymus on Peripheral Lymphoid Organs (1966) (1)
Erythrocyte Osmotic Fragility in AKR Mice with Lymphoid Leukæmia (1963) (1)
Factors in leukemic serum and urine stimulating bone marrow colony growth in vitro. Abstr. (1968) (1)
197: The apoptotic caspase cascade suppresses mitochondrial DNA-induced STING-mediated type I IFN production by dying cells (2014) (0)
A method for treatment and prophylaxis. (2003) (0)
Analysis of the distribution and characteristics of receptors for leukaemia inhibitory factor (1989) (0)
Analysis of the Cells Forming Pure and Mixed Erythroid Colonies in Agar after Stimulation by Pokeweed Mitogen-stimulated Spleen-conditioned Medium (1978) (0)
Inflammatory status guides dendritic cell development from different precursors (2005) (0)
Megakaryocyte Colony Formation (1977) (0)
Heterogeneity in Human Neutrophil , M acrophage , and Eosinophil Progenitor Cells (0)
172. DEVELOPMENT OF A NON-HORMONAL CONTRACEPTIVE: VAGINAL DELIVERY OF A LIF INHIBITOR: ITS TISSUE DISTRIBUTION AND EFFECT ON IMPLANTATION IN MICE (2009) (0)
ENU Mutagenesis Screen Identifies a Novel Regulator of Platelet Production. (2004) (0)
1964. Stem cell replacement in normal thymus grafts (1965) (0)
alpha-chain granulocyte-macrophage colony-stimulating factor receptor Neutralizing and nonneutralizing monoclonal antibodies to the human (2013) (0)
Therapeutic and diagnostic agents that regulate cellular responsiveness to cytokine (1997) (0)
Absence of yolk sac hematopoiesis from mice with a targeted disruption of the sci gene ( tall gene / gene targeting / homologous recombination ) (2005) (0)
The Hemopoietic Colony-Stimulating Factors: References (1995) (0)
Book Review:Handbook of the Hemopoietic Microenvironment. Contemporary Biomedicine. Mehdi Tavassoli (1990) (0)
dysregulated multi-CSF (IL-3) expression Nonneoplastic hematopoietic myeloproliferative syndrome induced by (2011) (0)
mechanism of receptor transmodulation in hematopoietic cells 3)-specific receptor beta-chain: implications for IL-3 function and the Functional inactivation in mice of the gene for the interleukin-3 (IL- (2011) (0)
Gm-csf polypeptide of mammal, its production and method for stimulating formation of granulocyte and macrophage (1996) (0)
NR6, an essential IL-12-like soluble member of the haemopoietin receptor family (1998) (0)
coordinately regulate megakaryocyte survival L (2013) (0)
Mouse Substrains IL-5 and Rp 105 Signaling Defects in B Cells (1999) (0)
Molecular genetics of the colony-stimulating factors and their receptors (1995) (0)
PL1-5 IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3 (2010) (0)
Nomenclature for secreted regulatory proteins of the immune system (interleukins). WHO-IUIS Nomenclature Subcommittee on Interleukin Designation. (1992) (0)
B 2 ' ' Super Repressor ' ' κ Generates an NF-Gene Nfkb 2 A Novel Mutation in the (2007) (0)
Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor (hemopoletic differentiation factor/yeast expression/gene sequence/evolution/oligonucleotide-mediated mutagenesis) (2016) (0)
Neoplastic Lymphoid and Plasmacytoma Colonies (1977) (0)
Book Review:Hematopoietic and Lymphoid Tissue in Culture. E. A. Luriya, Basil Haigh (1978) (0)
Colony Stimulating Factors:Past and Future (1990) (0)
Role for Interleukin-3 in Residual Megakaryocyte and Platelet Production Deficient Mice: No Physiologic - mpl Cytokine Production and Function in c- (2011) (0)
Characterization of TPO-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential (2012) (0)
Maturation and T Cell-Dependent Immune Associated with Defects in Both B Cell Nkx 2-3-Deficient Mice Are Intrinsic and Architectural Defects in the Spleens of Harvey and Lorraine (2003) (0)
Robustness insimple bioc h emic al netw orks (0)
Erythropoietin-independent erythroid colony formation z@ in@@ (1977) (0)
Regulation of Normal Hemopoiesis (1995) (0)
Use of an anti-g-csf or anti-g -csfr antibody or a soluble g- csfr for the treatment or prophylaxis of arthritis (2003) (0)
Hemopoietic cell colony proliferation stimulated by leukemic serum. Abstr. (1967) (0)
pulse stimulation by purified GM-CSF or G-CSF Proliferation of normal human promyelocytes and myelocytes after a single (2011) (0)
Eosinophil colonies in agar (1980) (0)
The thymus. Summary of the conference. (1964) (0)
Lineage priming in early hematopoietic progenitors as revealed by in vitro clone splitting experiments (2014) (0)
Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia (2012) (0)
with Lyn Deficiency Autoimmune Disease Normally Associated A Kinase-Dead Allele of Lyn Attenuates (2013) (0)
Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways (2012) (0)
Polyfunctional cytokines: IL-6 and LIF. Introduction. (1992) (0)
Robustness insimple biochemical networks (1997) (0)
ester for DNA synthesis interactions between the hematopoietic growth factors and with phorbol Activation and proliferation signals in murine macrophages: synergistic (2011) (0)
Receptor for granulocyte-macrophage colony stimulation factor and its derivatives (1990) (0)
A cellular and molecular analysis of the splenic hemopoiesis in mice treated with bacterial products. Abstr. (1980) (0)
Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells (2012) (0)
Overexpression of the ETS-family transcription factor ERG and dysregulated cytokine signaling drive erythroid leukemia development in mice (2013) (0)
Megakaryocytes possess functional apoptotic pathways that must be restrained in order to survive and produce platelets (2011) (0)
LYMPHOPENIA AND DEFECTIVE HEMATOPOIESIS IN THE LAMIN B RECEPTOR DEFICIENT ENU MUTANT MOUSE LYM3 (2010) (0)
B-LYMPHOCYTE COLONY FORMATION IN VITRO (1976) (0)
Hematopoietic regulators and signal transduction (1992) (0)
Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl (cid:1) / (cid:1) mice (2008) (0)
GM-Colony Formation in Myeloproliferative Disorders (1977) (0)
Pillars Article: Molecular Cloning of cDNA Encoding a Murine Haematopoietic Growth Regulator, Granulocyte-Macrophage Colony Stimulating Factor. Nature. 1984. 309: 763-767. (2017) (0)
leukemia inhibitory factor mice is not dependent on the actions of interleukin-6, interleukin-11, or deficient - The residual megakaryocyte and platelet production in c-Mpl (2013) (0)
Purification method of leukemia inhibitory factor (LIF) and pharmaceutical compositions containing polypeptides having LIF activity (1988) (0)
Leukemia inhibitory factor (LIF), DNA coding therefor, host cells with DNA as well as process for the preparation of LIF (1989) (0)
Differentiation during Lymphoid and Myeloid Cell and Heterogeneous Expression of IRF 8 A Reporter Mouse Reveals Lineage-Specific (2014) (0)
The kinetics of lymphocyte production in the normal and neoplastic thymus. (1967) (0)
In vitro Haemopoietic progenitor cell responses in mice with the transplanted lymphoid tumour ABE-8 (1980) (0)
Immunotherapy of Cancer in Man, E.M. Hersh, J.U. Gutterman, G. Mavligit. Charles C Thomas, Springfield, Ill (1973), 141 pp. US$9.50 (1974) (0)
The conserved SOCS box motif ih signaling binds to elongins B and proteins to proteasomal degradal (2016) (0)
HEMATOPOIESIS AND STEM CELLS Polycomb repressive complex 2 component Suz 12 is required for hematopoietic stem cell function and lymphopoiesis (2015) (0)
the Hematopoietic Compartment Drive Transgene Expression In Vivo Throughout vav Promoter Elements of (2010) (0)
Therapeutic and diagnostic agents that can modulate the cellular sensitivity to cytokines (1997) (0)
macrophage colony-stimulating factor Biologic properties in vitro of a recombinant human granulocyte- (2011) (0)
Understanding the molecular regulation of eosinophil production: a basis for intervention in inflammatory disease (2014) (0)
Role of the colony-stimulating factors in other disease states (1995) (0)
Regulation of hemopoiesis. (1978) (0)
The Bcl-2 Family: Arbiters of Life and Death (2000) (0)
Leukaemogenesis in AKR Mice (2008) (0)
The Thymus and Carcinogenesis (1966) (0)
The cell survival Bcl-w protein is required for spermatogenesis (1998) (0)
Hematopoietin receptor and gene sequences that code. (1996) (0)
promyelocytes and myelocytes The clonal proliferation in vitro of enriched populations of human (2011) (0)
SURVIVAL TIMES OF PASSIVELY TRANSFERRED HEMAGGLUTININS IN MICE (1964) (0)
Deficient hemic cell production in vivo but not in vitro by marrow of wvwv and wv&anemic mice. Abstr. (1968) (0)
Cytokines and placentation: The role of SOCS proteins (2006) (0)
Role of Nonhematopoietic Cells Local Production of Colony-stimulating Factor Within the Bone Marrow: (2011) (0)
Recent Results in Cancer Research 56. Lymphocytes, Macrophages and Cancer (1978) (0)
Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1. (2012) (0)
Established Bloodline: The Molecular Basis of Blood Diseases, 3rd Edition (2001) (0)
Urine Brief Report: Stimulation of Bone Marrow Colony Growth In Vitro by Human (2011) (0)
fractionation of various erythroid precursors Isolation of murine fetal hemopoietic progenitor cells and selective (2011) (0)
Declined Presentation: Critical roles for the homeodomain transcription factor hhex in lymphoid commitment and self-renewal of hematpoietic and leukaemic stem cells (2014) (0)
Trophic and other Functions of the Thymus (1966) (0)
Normal Mouse and Human Lymphocyte Colonies (1977) (0)
stress hematopoiesis in mice is required for self-renewal of hematopoietic stem cells during Erg (2011) (0)
Thymus grafts and leukemogenesis. Abstr. (1964) (0)
from culture: with studies of the effects of thrombocytopenia Measurement of ploidy distribution in megakaryocyte colonies obtained (2011) (0)
Host-cell repopulation of normal spleen grafts (1965) (0)
The Neutrophil.Patrick Murphy (1977) (0)
The role of Blimp-1 in lymphocyte terminal differentiation and homeostasis (2005) (0)
Necroptotic Death Of RIPK1-Deficient HSC Compromises Hematopoiesis (2013) (0)
A familyof cytokine-inducible inhibitorsof signalling (0)
The role of the thymus in autoimmunity. (1968) (0)
Membrane receptors on mouse bone marrow colony cells grown in vitro (1976) (0)
eosinophil colony formation Selective stimulation by mouse spleen cell conditioned medium of human (2012) (0)
monoclonal antibodies Separation of hemopoietic cells from adult mouse marrow by use of (2011) (0)
The thymus : a symposium held at the Wistar Institute of Anatomy and Biology, April 29, 1964 (1964) (0)
Lymphocyte Migration from the Thymus (1966) (0)
Identification of the Bone Marrow Colony Mononuclear 326 Blood (2005) (0)
CORRECTION (1987) (0)
Administered G-CSF boosts low affinity antibody production during T cell-dependent responses (2009) (0)
Biochemistry of the colony-stimulating factor receptors (1995) (0)
Normal and Malignant Hematopoiesis (1995) (0)
A Genetic Mutation on Murine Chromosome 7 Causes Thrombocytosis Associated with Thrombopoietin Excess - A Model of Jak2V617F Negative Idiopathic Thrombocytosis. (2005) (0)
Growth of adult mouse bone marrow erythroid and mixed erythroid colonies in vitro. Abstr. (1979) (0)
Role of the colony-stimulating factors in basal hemopoiesis (1995) (0)
[Bone marrow culture in agar and methylcellulose. Cytology of granulocytic colonies]. (1977) (0)
EDITORIAL HOW MANY CANCERS ARE REVERSIBLE OR SUPPRESSIBLE (1983) (0)
INTRODUCTION TO HEMATOPOIETIC STEM CELLS (1974) (0)
hemopoietic progenitor cells FADD and caspase-8 are required for cytokine-induced proliferation of (2013) (0)
Colony-stimulating factors in septic shock (2005) (0)
Sixth Annual Pezcoller Symposium: normal and malignant hematopoiesis--new advances. (1995) (0)
Normal and malignant hematopoiesis : new advances (1995) (0)
The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia (2016) (0)
Regulation of Hematopoietic Differentiation and Its Disruption Group Report (1985) (0)
Independent Actions in T Cell Homeostasis γ Suppressor of Cytokine Signaling-1 Has IFN - (2002) (0)
Genetic Approaches to the Investigation of the Mechanisms of Hematopoietic Progenitor Cell Mobilization into the Blood (1999) (0)

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