Eric N. Olson

Q: What Schools Are Affiliated With Eric N. Olson

Eric N. Olson is affiliated with the following schools: Emory University, MD Anderson Cancer Center, Wake Forest University, University of Chicago, Baylor College of Medicine, Columbia University, Maastricht University, Duke University, Medical College of Wisconsin, Allegheny University of the Health Sciences, University of Stuttgart, Vanderbilt University, University of Texas at Dallas, Johns Hopkins University, University of Texas Southwestern Medical Center, Harvard University

Eric N. Olson's AcademicInfluence.com Rankings

Eric N. Olson

Biology

#363

World Rank

#648

Historical Rank

#211

USA Rank

Molecular Biology

#52

World Rank

#53

Historical Rank

#37

USA Rank

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Biology

Why Is Eric N. Olson Influential?

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Eric N. Olson is a professor and chair of the Department of Molecular Biology, Robert A. Welch Distinguished Chair in Science, the Annie and Willie Nelson Professor of Stem Cell Research, and the Pogue Distinguished Chair in Research on Cardiac Birth Defects for the UT Southwestern Medical Center. He earned a B.A. in chemistry and biology and a Ph.D. in biochemistry from Wake Forest University. He completed his postdoctoral studies at the Washington University School of Medicine.

Olson and his team have worked to better understand how the heart develops and works, as well as the behaviors of diseases and disorders of the cardiovascular and skeletal muscle tissue. He has provided fellow scientists with a blueprint for tissue formation and revealed the function of epigenetic mechanisms and microRNAs on the development of muscle tissue.

He has co-founded a number of biotechnology companies to take their scientific findings to create devices and therapeutic protocols that help patients with muscle diseases and cardiac conditions. Olson has received a number of important awards, including the Gill Heart Institute Award for Outstanding Contributions to Cardiovascular Medicine, the Pasarow Award in Cardiovascular Medicine, the Founding Distinguished Scientist Award from the American Heart Association, and the LeFoulon Delalande Grand Prix Award from the Institut de France and the French Academy of Science.

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Featured in Top Influential Biologists Today

According to Wikipedia, Eric Newell Olson is an American molecular biologist. He is professor and chair of the Department of Molecular Biology at the University of Texas Southwestern Medical Center in Dallas, where he also holds the Robert A. Welch Distinguished Chair in Science, the Annie and Willie Nelson Professorship in Stem Cell Research, and the Pogue Distinguished Chair in Research on Cardiac Birth Defects.

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Eric N. Olson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy (1998) (2645)
The many roles of histone deacetylases in development and physiology: implications for disease and therapy (2009) (2252)
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres (2002) (2201)
Transient Regenerative Potential of the Neonatal Mouse Heart (2011) (2045)
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis (2008) (1721)
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. (2008) (1698)
MicroRNAs in Stress Signaling and Human Disease (2012) (1547)
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure (2006) (1515)
Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA (2007) (1490)
Cardiac hypertrophy: the good, the bad, and the ugly. (2003) (1468)
NFAT Signaling Choreographing the Social Lives of Cells (2002) (1347)
Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene (1993) (1319)
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. (2002) (1310)
Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection (2009) (1243)
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. (1997) (1219)
Pervasive roles of microRNAs in cardiovascular biology (2011) (1133)
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation (2000) (1078)
Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. (1998) (1064)
Heart repair by reprogramming non-myocytes with cardiac transcription factors (2012) (1060)
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. (1998) (1040)
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. (1997) (985)
Class II Histone Deacetylases Act as Signal-Responsive Repressors of Cardiac Hypertrophy (2002) (976)
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. (2009) (920)
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. (2010) (916)
Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore (2004) (904)
Activation of Cardiac Gene Expression by Myocardin, a Transcriptional Cofactor for Serum Response Factor (2001) (896)
Cardiac plasticity. (2008) (883)
A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance (2015) (879)
Linking actin dynamics and gene transcription to drive cellular motile functions (2010) (871)
Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins (1995) (864)
Deacetylase inhibition promotes the generation and function of regulatory T cells (2007) (846)
Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer (2002) (838)
Hypertrophy of the heart: a new therapeutic target? (2004) (820)
Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments. (2001) (799)
Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy (2016) (799)
Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis (2004) (785)
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. (2008) (780)
Signaling pathways in skeletal muscle remodeling. (2006) (773)
MEF2: a central regulator of diverse developmental programs (2007) (761)
Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND (1997) (715)
Hippo pathway effector Yap promotes cardiac regeneration (2013) (709)
MEF2: a calcium-dependent regulator of cell division, differentiation and death. (2002) (709)
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. (2007) (708)
bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. (1994) (705)
MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice (2009) (693)
MyoD family: a paradigm for development? (1990) (680)
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. (2009) (676)
A twist code determines the onset of osteoblast differentiation. (2004) (670)
IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1 (1999) (668)
A genetic blueprint for cardiac development (2000) (663)
A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. (1989) (653)
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family (2012) (633)
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth (2003) (609)
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. (2010) (603)
Histone Deacetylases 5 and 9 Govern Responsiveness of the Heart to a Subset of Stress Signals and Play Redundant Roles in Heart Development (2004) (599)
Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure (2011) (592)
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles (2012) (589)
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo (2002) (587)
Macrophages are required for neonatal heart regeneration. (2014) (586)
Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli (2007) (586)
A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes. (1989) (584)
Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4 (1996) (583)
MicroRNAs add a new dimension to cardiovascular disease. (2010) (577)
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. (1994) (573)
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression (2004) (570)
A Subclass of bHLH Proteins Required for Cardiac Morphogenesis (1995) (561)
A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle (2016) (548)
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. (2000) (546)
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. (2007) (545)
Gene Regulatory Networks in the Evolution and Development of the Heart (2006) (545)
Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. (2000) (541)
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. (2000) (535)
MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1 (2014) (533)
Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5 (2004) (530)
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5. (2000) (520)
Myocardin is a master regulator of smooth muscle gene expression (2003) (512)
Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons (2007) (512)
HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction (2009) (510)
Molecular Pathways Controlling Heart Development (1996) (509)
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. (2006) (498)
Prevention of cardiac hypertrophy in mice by calcineurin inhibition. (1998) (495)
Potentiation of serum response factor activity by a family of myocardin-related transcription factors (2002) (494)
PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands (1998) (487)
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. (2006) (485)
MicroRNA regulatory networks in cardiovascular development. (2010) (481)
The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. (2006) (481)
Defining the regulatory networks for muscle development. (1996) (477)
Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size (2011) (476)
MEF2 responds to multiple calcium‐regulated signals in the control of skeletal muscle fiber type (2000) (475)
Reprogramming of human fibroblasts toward a cardiac fate (2013) (473)
Inhibition of miR-15 Protects Against Cardiac Ischemic Injury (2012) (470)
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. (2006) (468)
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. (2004) (464)
Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo (2002) (459)
Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo * (2000) (451)
Regulation of the MEF2 Family of Transcription Factors by p38 (1999) (447)
Control of muscle development by dueling HATs and HDACs. (2001) (446)
Interplay between proliferation and differentiation within the myogenic lineage. (1992) (445)
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. (1996) (444)
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. (2005) (443)
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133 (2007) (441)
Histone Deacetylase 7 Maintains Vascular Integrity by Repressing Matrix Metalloproteinase 10 (2006) (438)
Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair (2013) (434)
Control of cardiac growth by histone acetylation/deacetylation. (2005) (431)
Twist Regulates Cytokine Gene Expression through a Negative Feedback Loop that Represses NF-κB Activity (2003) (425)
miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes (2011) (423)
AngiomiRs--key regulators of angiogenesis. (2009) (420)
SM22 alpha, a marker of adult smooth muscle, is expressed in multiple myogenic lineages during embryogenesis. (1996) (418)
Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs (2011) (418)
MEF2C transcription factor controls chondrocyte hypertrophy and bone development. (2007) (409)
The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload (2009) (403)
Toward microRNA-based therapeutics for heart disease: the sense in antisense. (2008) (402)
Sizing up the heart: development redux in disease. (2003) (400)
Regulation of myogenic differentiation by type beta transforming growth factor (1986) (396)
Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. (2007) (391)
Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis. (1994) (390)
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. (2010) (389)
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. (2009) (388)
Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases (2010) (382)
Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA (2014) (378)
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors (2012) (376)
Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. (1995) (373)
Activation of MEF2 by muscle activity is mediated through a calcineurin‐dependent pathway (2001) (368)
Myomaker: A membrane activator of myoblast fusion and muscle formation (2013) (368)
Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors. (1995) (365)
Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1 (1998) (361)
Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker Genes (2003) (358)
Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486 (2010) (357)
Decoding calcium signals involved in cardiac growth and function (2000) (355)
MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death. (2012) (355)
Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy (2018) (354)
Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5 (2003) (354)
The serum response factor coactivator myocardin is required for vascular smooth muscle development (2003) (354)
Suppression of Class I and II Histone Deacetylases Blunts Pressure-Overload Cardiac Hypertrophy (2006) (350)
Independent Signals Control Expression of the Calcineurin Inhibitory Proteins MCIP1 and MCIP2 in Striated Muscles (2000) (349)
A Cardiac MicroRNA Governs Systemic Energy Homeostasis by Regulation of MED13 (2012) (347)
MicroRNA control of muscle development and disease. (2009) (346)
Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23∼27∼24 clusters (2011) (340)
Unveiling the Mechanisms of Cell-Cell Fusion (2005) (333)
MicroRNAs flex their muscles. (2008) (331)
Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction (2010) (330)
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice. (2008) (328)
FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains (1992) (328)
Requirement of the MADS-box transcription factor MEF2C for vascular development. (1998) (328)
Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies. (1995) (327)
The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. (1995) (326)
Expression of the SM22alpha promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells (1996) (324)
MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation. (1999) (324)
Control of cardiac development by an evolutionarily conserved transcriptional network. (2002) (323)
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner (2004) (321)
A decade of discoveries in cardiac biology (2004) (320)
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor (2002) (318)
HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors (1992) (315)
Calcineurin Signaling and Muscle Remodeling (2000) (314)
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo (2001) (309)
Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2 (1992) (305)
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis (2002) (305)
Calsarcins, a novel family of sarcomeric calcineurin-binding proteins. (2000) (302)
Myogenin is required for late but not early aspects of myogenesis during mouse development (1995) (300)
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. (2005) (300)
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development (2009) (296)
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy (2001) (295)
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. (1999) (292)
PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system (1995) (292)
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. (2012) (292)
HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. (1999) (290)
Toward transcriptional therapies for the failing heart: chemical screens to modulate genes. (2005) (287)
Identification of a Signal-Responsive Nuclear Export Sequence in Class II Histone Deacetylases (2001) (287)
Remodeling muscles with calcineurin (2000) (285)
Dilated Cardiomyopathy and Sudden Death Resulting From Constitutive Activation of Protein Kinase A (2001) (281)
Calmodulin Kinase II and Arrhythmias in a Mouse Model of Cardiac Hypertrophy (2002) (279)
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. (2005) (277)
Dose-dependent Blockade to Cardiomyocyte Hypertrophy by Histone Deacetylase Inhibitors* (2003) (276)
MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer. (1992) (268)
A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. (1998) (268)
Helix-loop-helix proteins as regulators of muscle-specific transcription. (1993) (267)
A Role for miR-145 in Pulmonary Arterial Hypertension: Evidence From Mouse Models and Patient Samples (2012) (266)
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors. (1993) (265)
Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378* (2012) (265)
Canonical Transient Receptor Potential Channels Promote Cardiomyocyte Hypertrophy through Activation of Calcineurin Signaling* (2006) (264)
Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development (2016) (261)
MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function (2008) (261)
MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment. (2013) (261)
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression. (2004) (259)
Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. (1995) (258)
Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products (1991) (257)
Association of Class II Histone Deacetylases with Heterochromatin Protein 1: Potential Role for Histone Methylation in Control of Muscle Differentiation (2002) (256)
Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. (2000) (254)
Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. (1995) (254)
Separable regulatory elements governing myogenin transcription in mouse embryogenesis. (1993) (253)
Twist mediates suppression of inflammation by type I IFNs and Axl (2006) (249)
Acylation of proteins with myristic acid occurs cotranslationally. (1987) (249)
Specific Interaction of the PDZ Domain Protein PICK1 with the COOH Terminus of Protein Kinase C-α* (1997) (247)
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. (2002) (247)
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. (2007) (245)
Requirement of the paraxis gene for somite formation and musculoskeletal patterning (1996) (243)
Control of muscle formation by the fusogenic micropeptide myomixer (2017) (240)
Modulation of Cardiac Growth and Development by HOP, an Unusual Homeodomain Protein (2002) (239)
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. (2008) (238)
The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development. (2000) (237)
Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene (1988) (235)
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. (2003) (235)
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7 (2008) (232)
Requirement of protein kinase D1 for pathological cardiac remodeling (2008) (232)
A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing (1994) (231)
Immune modulation of stem cells and regeneration. (2014) (230)
Epigenetic control of skull morphogenesis by histone deacetylase 8. (2009) (228)
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy (2003) (227)
FOG-2, a Heart- and Brain-Enriched Cofactor for GATA Transcription Factors (1999) (226)
ΔFosB Mediates Epigenetic Desensitization of the c-fos Gene After Chronic Amphetamine Exposure (2008) (223)
Association of COOH-terminal-binding Protein (CtBP) and MEF2-interacting Transcription Repressor (MITR) Contributes to Transcriptional Repression of the MEF2 Transcription Factor* (2001) (222)
Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. (2010) (222)
Control of smooth muscle development by the myocardin family of transcriptional coactivators. (2004) (220)
Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression. (1992) (220)
D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. (1994) (219)
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress (2004) (219)
MicroRNAs as Therapeutic Targets and Biomarkers of Cardiovascular Disease (2014) (218)
A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila. (1995) (217)
Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites. (1995) (217)
Muscle-Specific Signaling Mechanism That Links Actin Dynamics to Serum Response Factor (2005) (214)
Wingless signaling induces nautilus expression in the ventral mesoderm of the Drosophila embryo. (1996) (213)
CaMKIIδ Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses* (2007) (211)
Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization. (1990) (211)
Therapeutic approaches for cardiac regeneration and repair (2018) (210)
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. (2005) (210)
The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. (1998) (209)
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing (2020) (208)
An Essential Role for Histone Deacetylase 4 in Synaptic Plasticity and Memory Formation (2012) (206)
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation (2013) (206)
Gene Expression by a MicroRNA Control of Stress-Dependent Cardiac Growth (2008) (204)
Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. (1999) (203)
Regulation of Skeletal Muscle Sarcomere Integrity and Postnatal Muscle Function by Mef2c (2007) (198)
Nkx2–5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo (2009) (198)
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury (2016) (197)
The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation (1987) (197)
Requirement of a Myocardin-Related Transcription Factor for Development of Mammary Myoepithelial Cells (2006) (195)
Signaling chromatin to make muscle. (2002) (194)
Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C (1996) (194)
Control of Facial Muscle Development by MyoR and Capsulin (2002) (193)
Calsarcin-3, a Novel Skeletal Muscle-specific Member of the Calsarcin Family, Interacts with Multiple Z-disc Proteins* (2002) (192)
Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice. (1998) (190)
Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice. (1998) (190)
Modulation of Smooth Muscle Gene Expression by Association of Histone Acetyltransferases and Deacetylases with Myocardin (2005) (189)
Regulation of Microtubule Dynamics and Myogenic Differentiation by Murf, a Striated Muscle Ring-Finger Protein (2000) (188)
MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs (2010) (188)
The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. (2001) (188)
Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. (1999) (187)
Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure. (1999) (183)
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. (2006) (183)
C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury (2012) (183)
Parsing the Heart: Genetic Modules for Organ Assembly (1997) (182)
Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication (2016) (182)
Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells. (1997) (181)
MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. (1999) (180)
Regulation of muscle transcription by the MyoD family. The heart of the matter. (1993) (178)
CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice (2017) (177)
A Common Progenitor at the Heart of Development (2006) (176)
Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing (2018) (176)
Sex modifies exercise and cardiac adaptation in mice. (2004) (176)
Calcium/Calmodulin-Dependent Protein Kinase II Contributes to Cardiac Arrhythmogenesis in Heart Failure (2009) (173)
Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. (2004) (173)
Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta. (2010) (173)
The Transcriptional Coactivator CAMTA2 Stimulates Cardiac Growth by Opposing Class II Histone Deacetylases (2006) (171)
Histone Deacetylase 5 Acquires Calcium/Calmodulin-Dependent Kinase II Responsiveness by Oligomerization with Histone Deacetylase 4 (2008) (170)
Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation. (1986) (169)
Control of Myoblast Fusion by a Guanine Nucleotide Exchange Factor, Loner, and Its Effector ARF6 (2003) (168)
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism. (2013) (168)
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy (2017) (167)
Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression (2005) (166)
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex (2014) (164)
HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination (2011) (164)
Multiple Roles for the MyoD Basic Region in Transmission of Transcriptional Activation Signals and Interaction with MEF2 (1998) (164)
Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size (2006) (163)
Renaming the DSCR1 / Adapt78 gene family as RCAN: regulators of calcineurin (2007) (163)
Protein Kinase D-dependent Phosphorylation and Nuclear Export of Histone Deacetylase 5 Mediates Vascular Endothelial Growth Factor-induced Gene Expression and Angiogenesis* (2008) (162)
A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart. (2000) (162)
The basic helix-loop-helix transcription factor, dHAND, is required for vascular development. (2000) (162)
Mining for Micropeptides. (2017) (162)
The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis. (1998) (161)
A neonatal blueprint for cardiac regeneration. (2014) (159)
Regulation of Cardiac Stress Signaling by Protein Kinase D1 (2006) (158)
Muscle as a "mediator" of systemic metabolism. (2015) (158)
Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution (2019) (157)
D‐mef2 is a target for Tinman activation during Drosophila heart development (1997) (157)
Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. (2005) (156)
Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila. (2001) (155)
The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. (2001) (155)
Myocardin Induces Cardiomyocyte Hypertrophy (2006) (154)
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development (2016) (154)
Myogenin's functions do not overlap with those of MyoD or Myf-5 during mouse embryogenesis. (1995) (154)
Specificity of fatty acid acylation of cellular proteins. (1985) (154)
Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs (1998) (154)
Converging Pathways and Principles in Heart Development and Disease CV@CSH (2002) (153)
MicroRNA-218 Regulates Vascular Patterning by Modulation of Slit-Robo Signaling (2010) (152)
Class I HDAC Inhibition Blocks Cocaine-Induced Plasticity Through Targeted Changes in Histone Methylation (2013) (152)
Fatty acylated proteins as components of intracellular signaling pathways. (1990) (152)
CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells (2019) (150)
Control by fibroblast growth factor of differentiation in the BC3H1 muscle cell line (1985) (150)
Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes (2015) (150)
Control of Cardiac Growth and Function by Calcineurin Signaling* (2003) (148)
Essential Role for Protein Kinase D Family Kinases in the Regulation of Class II Histone Deacetylases in B Lymphocytes (2006) (148)
The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3 (2019) (147)
A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9 (2015) (147)
Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function (2009) (147)
Protein Kinase D1 Phosphorylates HDAC7 and Induces Its Nuclear Export after T-cell Receptor Activation* (2005) (146)
Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats. (1999) (146)
Requirement of MEF2A, C, and D for skeletal muscle regeneration (2014) (146)
Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides (2016) (145)
HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration (2013) (145)
Abnormalities of the Genitourinary Tract in Female Mice Lacking GATA5 (2000) (145)
Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy. (2011) (144)
Regulation of paraxis expression and somite formation by ectoderm- and neural tube-derived signals. (1997) (143)
Activated Notch Inhibits Myogenic Activity of the MADS-Box Transcription Factor Myocyte Enhancer Factor 2C (1999) (143)
Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHox. (1997) (143)
A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. (1990) (142)
Skeletal Muscle Reprogramming by Activation of Calcineurin Improves Insulin Action on Metabolic Pathways* (2003) (142)
Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis. (1991) (142)
Towards a molecular pathway for myoblast fusion in Drosophila. (2004) (142)
Regulation of HDAC9 Gene Expression by MEF2 Establishes a Negative-Feedback Loop in the Transcriptional Circuitry of Muscle Differentiation (2006) (141)
Reptilian heart development and the molecular basis of cardiac chamber evolution (2009) (141)
Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development (2006) (141)
Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site. (2002) (139)
HDAC4 inhibits cell‐cycle progression and protects neurons from cell death (2008) (139)
Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer. (2001) (139)
Modular regulation of muscle gene transcription: a mechanism for muscle cell diversity. (1997) (139)
Expression of the Smooth Muscle Cell Calponin Gene Marks the Early Cardiac and Smooth Muscle Cell Lineages during Mouse Embryogenesis (*) (1996) (137)
Cardiac histone acetylation--therapeutic opportunities abound. (2004) (137)
Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development (2003) (136)
G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1 (2012) (135)
MEF2B is a potent transactivator expressed in early myogenic lineages (1996) (135)
Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. (2009) (134)
Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype? (1999) (133)
Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. (1991) (133)
Myomaker is essential for muscle regeneration (2014) (133)
Cardiogenic small molecules that enhance myocardial repair by stem cells (2008) (132)
Identification of a prx1 limb enhancer (2000) (131)
A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Repair (2011) (130)
Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice (2012) (129)
Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. (2000) (129)
Retinoid receptor expression and all-trans retinoic acid-mediated growth inhibition in vascular smooth muscle cells. (1996) (129)
Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4 (2011) (128)
Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6 (2011) (128)
Surgical models for cardiac regeneration in neonatal mice (2014) (128)
The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. (2000) (128)
Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation. (2008) (128)
Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart. (2000) (127)
STARS, a Striated Muscle Activator of Rho Signaling and Serum Response Factor-dependent Transcription* (2002) (127)
Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR. (2006) (126)
Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis (2005) (126)
Overview of the Alliance for Cellular Signaling (2002) (125)
BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart (2005) (124)
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development (2012) (123)
The expression pattern of the chick homeobox gene gMHox suggests a role in patterning of the limbs and face and in compartmentalization of somites. (1994) (122)
Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors (2014) (122)
PRISM/PRDM6, a Transcriptional Repressor That Promotes the Proliferative Gene Program in Smooth Muscle Cells (2006) (121)
A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle (1994) (120)
MyoD Meets Its Maker (1997) (120)
Cardiac CaM Kinase II Genes &dgr; and &ggr; Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy (2014) (119)
The γ isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption (2009) (119)
Histone Deacetylase 9 Is a Negative Regulator of Adipogenic Differentiation* (2011) (118)
The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis (2001) (118)
Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration. (2005) (117)
Death, Cardiac Dysfunction, and Arrhythmias Are Increased by Calmodulin Kinase II in Calcineurin Cardiomyopathy (2006) (117)
An expression screen reveals modulators of class II histone deacetylase phosphorylation. (2005) (116)
Activation of MRTF-A–dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing (2013) (115)
Nuclear Factor-&kgr;B Protects the Adult Cardiac Myocyte Against Ischemia-Induced Apoptosis in a Murine Model of Acute Myocardial Infarction (2003) (115)
MCIP1 Overexpression Suppresses Left Ventricular Remodeling and Sustains Cardiac Function After Myocardial Infarction (2004) (114)
Myocyte enhancer binding factor-2 expression and activity in vascular smooth muscle cells. Association with the activated phenotype. (1996) (113)
Phosphorylation of the MADS-Box Transcription Factor MEF2C Enhances Its DNA Binding Activity* (1996) (113)
EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature. (1999) (112)
Hand2 function in second heart field progenitors is essential for cardiogenesis. (2011) (112)
Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility (2013) (112)
Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9 (2011) (111)
CRISPR Correction of Duchenne Muscular Dystrophy. (2019) (110)
FoxO4 Regulates Tumor Necrosis Factor Alpha-Directed Smooth Muscle Cell Migration by Activating Matrix Metalloproteinase 9 Gene Transcription (2007) (110)
Cardiac-specific Expression of Calcineurin Reverses Embryonic Lethality in Calreticulin-deficient Mouse* (2002) (109)
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function (2007) (109)
The Mouse MRF4 Promoter Is trans-Activated Directly and Indirectly by Muscle-specific Transcription Factors (*) (1995) (108)
Development of chromaffin cells depends on MASH1 function. (2002) (108)
Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators (2013) (108)
The specific role of histone deacetylase 2 in adult neurogenesis. (2010) (107)
Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development (2010) (107)
Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. (1999) (106)
Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage (2002) (106)
The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription (1992) (106)
Genetic dissection of histone deacetylase requirement in tumor cells (2009) (106)
Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. (2005) (105)
Neuroprotection by Histone Deacetylase-Related Protein (2006) (105)
Protein Kinase D1 Stimulates MEF2 Activity in Skeletal Muscle and Enhances Muscle Performance (2008) (105)
In Vivo Analysis of MEF2 Transcription Factors in Synapse Regulation and Neuronal Survival (2012) (104)
Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. (2013) (104)
A mouse model of rhabdomyosarcoma originating from the adipocyte lineage. (2012) (103)
KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy. (2014) (102)
Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding. (2002) (102)
Redundant Control of Adipogenesis by Histone Deacetylases 1 and 2* (2010) (102)
A Twist2-Dependent Progenitor Cell Contributes to Adult Skeletal Muscle (2017) (101)
A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway. (2004) (101)
Hand, an evolutionarily conserved bHLH transcription factor required for Drosophila cardiogenesis and hematopoiesis (2006) (101)
Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity. (2007) (101)
Cyclic AMP-dependent protein kinase inhibits the activity of myogenic helix-loop-helix proteins (1992) (99)
Calcineurin Is Necessary for the Maintenance but Not Embryonic Development of Slow Muscle Fibers (2005) (99)
Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity (2017) (99)
Cardiac hypertrophy: sorting out the circuitry. (1999) (97)
Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development. (2016) (96)
MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation (2018) (96)
Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. (2013) (95)
Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation (2007) (95)
hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function (2015) (94)
Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction (2007) (94)
A retinoic acid-induced clonal cell line derived from multipotential P19 embryonal carcinoma cells expresses smooth muscle characteristics. (1995) (94)
Deletion of the regulatory domain of protein kinase C alpha exposes regions in the hinge and catalytic domains that mediate nuclear targeting (1992) (94)
Regulation of vertebrate myotome development by the p38 MAP kinase-MEF2 signaling pathway. (2005) (93)
Fatty acylation of cellular proteins. Temporal and subcellular differences between palmitate and myristate acylation. (1986) (92)
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus (2005) (92)
Identification of Direct Serum-response Factor Gene Targets during Me2SO-induced P19 Cardiac Cell Differentiation* (2005) (90)
Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus (2000) (90)
Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation. (1996) (90)
The Cardiac CaMKII Genes δ and γ Contribute Redundantly to Adverse Remodeling but Inhibit Calcineurin-Induced Myocardial Hypertrophy (2014) (90)
Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. (2016) (89)
Mef 2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis (1994) (89)
From the sarcomere to the nucleus: role of genetics and signaling in structural heart disease. (2000) (89)
Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor. (1990) (88)
Repression of myogenin function by TGF-beta 1 is targeted at the basic helix-loop-helix motif and is independent of E2A products. (1992) (88)
GATA4: a novel transcriptional regulator of cardiac hypertrophy? (1997) (86)
Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest (2015) (86)
Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation (1987) (85)
Myocardin Sumoylation Transactivates Cardiogenic Genes in Pluripotent 10T1/2 Fibroblasts (2006) (85)
A comparative molecular analysis of four rat smooth muscle cell lines (1998) (84)
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2 (2014) (84)
Searching for miR-acles in cardiac fibrosis. (2009) (83)
Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells [published erratum appears in J Cell Biol 1990 Jun;110(6):2231] (1990) (83)
Alpha and beta subunits of the nicotinic acetylcholine receptor contain covalently bound lipid. (1984) (82)
HDAC4 Represses Matrix Metalloproteinase-13 Transcription in Osteoblastic Cells, and Parathyroid Hormone Controls This Repression* (2010) (82)
Decrease in transforming growth factor-beta binding and action during differentiation in muscle cells. (1988) (81)
Identification of genes regulated during mechanical load-induced cardiac hypertrophy. (2000) (81)
Control of cardiac hypertrophy and heart failure by histone acetylation/deacetylation. (2006) (81)
Toward the Goal of Human Heart Regeneration. (2020) (81)
The Mevalonate Pathway Controls Heart Formation in Drosophila by Isoprenylation of Gγ1 (2006) (81)
Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding (1991) (81)
Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy. (2004) (81)
Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system (2020) (81)
Homeodomain protein MHox and MADS protein myocyte enhancer-binding factor-2 converge on a common element in the muscle creatine kinase enhancer. (1994) (80)
Cooperative Transcriptional Activation by the Neurogenic Basic Helix-Loop-Helix Protein MASH1 and Members of the Myocyte Enhancer Factor-2 (MEF2) Family* (1996) (80)
MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver (2014) (80)
Different MRF4 knockout alleles differentially disrupt Myf-5 expression: cis-regulatory interactions at the MRF4/Myf-5 locus. (1997) (79)
Two Novel Members of the ABLIM Protein Family, ABLIM-2 and -3, Associate with STARS and Directly Bind F-actin* (2007) (79)
Transcriptional Regulation of Cardiac Progenitor Cell Populations (2004) (79)
Two distinct Xenopus genes with homology to MyoD1 are expressed before somite formation in early embryogenesis (1990) (79)
Regulation of surface expression of acetylcholine receptors in response to serum and cell growth in the BC3H1 muscle cell line. (1983) (79)
Mapping of myogenin transcription during embryogenesis using transgenes linked to the myogenin control region (1992) (78)
Muscle : fundamental biology and mechanisms of disease (2012) (77)
Muscle Specificity Encoded by Specific Serum Response Factor-binding Sites* (2001) (77)
A myocardin-related transcription factor regulates activity of serum response factor in Drosophila. (2004) (76)
Activated calcineurin ameliorates contraction‐induced injury to skeletal muscles of mdx dystrophic mice (2006) (75)
Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. (2006) (75)
Angiotensin II Stimulates Protein Kinase D–Dependent Histone Deacetylase 5 Phosphorylation and Nuclear Export Leading to Vascular Smooth Muscle Cell Hypertrophy (2007) (75)
The A10 cell line: a model for neonatal, neointimal, or differentiated vascular smooth muscle cells? (1997) (75)
Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay (2009) (74)
Protein kinase C as a transducer of nuclear signals. (1993) (73)
Functional correction of dystrophin actin binding domain mutations by genome editing. (2017) (73)
Regulation of creatine phosphokinase expression during differentiation of BC3H1 cells. (1983) (72)
Common Genomic Response in Different Mouse Models of &bgr;-Adrenergic–Induced Cardiomyopathy (2003) (72)
Binding of TFIID and MEF2 to the TATA element activates transcription of the Xenopus MyoDa promoter (1994) (72)
ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression (2017) (71)
Role of calcineurin in striated muscle: development, adaptation, and disease. (2003) (71)
Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes (2011) (71)
Twist-2 Controls Myeloid Lineage Development and Function (2008) (71)
Alteration of Mesodermal Cell Differentiation by EWS/FLI-1, the Oncogene Implicated in Ewing's Sarcoma (2003) (70)
Signal transduction pathways that regulate skeletal muscle gene expression. (1993) (70)
Chicken Nkx-2.8: a novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. (1997) (70)
Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C. (2009) (70)
Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle (2000) (70)
Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling (2019) (69)
MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells. (2001) (69)
Regulation of Acetylation of Histone Deacetylase 2 by p300/CBP-Associated Factor/Histone Deacetylase 5 in the Development of Cardiac Hypertrophy (2014) (69)
CREST - a large and diverse superfamily of putative transmembrane hydrolases (2011) (69)
The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy (2018) (69)
The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas. (1999) (69)
Dexamethasone-dependent inhibition of differentiation of C2 myoblasts bearing steroid-inducible N-ras oncogenes (1988) (69)
Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression. (2015) (68)
Heterodimers of myogenic helix-loop-helix regulatory factors and E12 bind a complex element governing myogenic induction of the avian cardiac alpha-actin promoter (1991) (68)
Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. (2012) (67)
MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration. (2012) (67)
HRC Is a Direct Transcriptional Target of MEF2 during Cardiac, Skeletal, and Arterial Smooth Muscle Development In Vivo (2004) (66)
A myogenic factor from sea urchin embryos capable of programming muscle differentiation in mammalian cells. (1991) (65)
Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. (2007) (65)
Differential trans-activation of a muscle-specific enhancer by myogenic helix-loop-helix proteins is separable from DNA binding. (1991) (65)
Overexpression of a Single Helix-Loop-Helix-type Transcription Factor, Scleraxis, Enhances Aggrecan Gene Expression in Osteoblastic Osteosarcoma ROS17/2.8 Cells* (1997) (65)
Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. (2019) (65)
Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2 (2010) (64)
Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction. (2003) (64)
Hypothalamic leptin action is mediated by histone deacetylase 5 (2016) (63)
Homozygous nonsense mutations in TWIST2 cause Setleis syndrome. (2010) (63)
Myogenin and acetylcholine receptor alpha gene promoters mediate transcriptional regulation in response to motor innervation. (1994) (63)
Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. (1996) (63)
The MEF2A 3' untranslated region functions as a cis-acting translational repressor (1997) (63)
An activated c-Ha-ras allele blocks the induction of muscle-specific genes whose expression is contingent on mitogen withdrawal. (1987) (62)
The Multifunctional Ca2+/Calmodulin-dependent Kinase II δ (CaMKIIδ) Controls Neointima Formation after Carotid Ligation and Vascular Smooth Muscle Cell Proliferation through Cell Cycle Regulation by p21* (2010) (62)
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing. (2020) (62)
Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing (2021) (62)
A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome (2017) (62)
Dual roles of histone deacetylases in the control of cardiac growth. (2004) (62)
Target Gene-Specific Modulation of Myocardin Activity by GATA Transcription Factors (2004) (61)
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis (2018) (61)
Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae. (2013) (61)
Hairy-related Transcription Factors Inhibit GATA-dependent Cardiac Gene Expression through a Signal-responsive Mechanism* (2004) (61)
Assembling a functional tympanic membrane: signals from the external acoustic meatus coordinate development of the malleal manubrium. (2000) (61)
Yap and Taz play a crucial role in neural crest-derived craniofacial development (2016) (60)
Overexpression and knockout of miR-126 both promote leukemogenesis. (2015) (60)
The LIM protein, CRP1, is a smooth muscle marker (1999) (60)
Interactions among vertebrate helix-loop-helix proteins in yeast using the two-hybrid system. (1993) (59)
Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila. (2008) (59)
The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice. (2001) (59)
Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression. (2005) (59)
Identification of a novel fatty acylated protein that partitions between the plasma membrane and cytosol and is deacylated in response to serum and growth factor stimulation. (1989) (58)
Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I (2016) (58)
E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins (1993) (58)
Myozap, a Novel Intercalated Disc Protein, Activates Serum Response Factor–Dependent Signaling and Is Required to Maintain Cardiac Function In Vivo (2010) (58)
Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. (1999) (58)
microRNAs put their signatures on the heart. (2007) (58)
The Mef 2 c gene is a direct transcriptional target of myogenic bHLH and MEF 2 proteins during skeletal muscle development (2001) (57)
Reversibility of Adverse, Calcineurin-Dependent Cardiac Remodeling (2011) (57)
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution (2020) (57)
Stac3 has a direct role in skeletal muscle-type excitation–contraction coupling that is disrupted by a myopathy-causing mutation (2016) (57)
Structure–function analysis of myomaker domains required for myoblast fusion (2016) (56)
Regulation of muscle cell growth and differentiation by the MyoD family of helix-loop-helix proteins. (1992) (56)
Heart development: learning from mistakes. (2002) (56)
Alterations of L-Type Calcium Current and Cardiac Function in CaMKII&dgr; Knockout Mice (2010) (56)
Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression (2013) (56)
Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy (2010) (56)
Positive autoregulation of the Myocyte enhancer factor-2 myogenic control gene during somatic muscle development in Drosophila. (2004) (55)
signaling in cardiac myocyte excitation- transcription coupling (2006) (55)
Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor (2010) (55)
Skeletal muscle remodeling (2007) (55)
Heart repair by cardiac reprogramming (2013) (55)
Mitogenic repression of myogenin autoregulation. (1991) (55)
Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila (2014) (55)
Dimerization through the helix-loop-helix motif enhances phosphorylation of the transcription activation domains of myogenin (1994) (54)
Suppression of proliferation and cardiomyocyte hypertrophy by CHAMP, a cardiac-specific RNA helicase (2002) (54)
Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblasts. (2009) (54)
Identification of a thyroid hormone response element in the mouse myogenin gene: characterization of the thyroid hormone and retinoid X receptor heterodimeric binding site. (1993) (53)
The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate. (2008) (53)
Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist (2017) (53)
Cooperative Transcriptional Activation by Serum Response Factor and the High Mobility Group Protein SSRP1* (1999) (53)
Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration (2018) (53)
The Path to the Heart and the Road Not Taken (2001) (52)
Mitogens and protein synthesis inhibitors induce ornithine decarboxylase gene transcription through separate mechanisms in the BC3H1 muscle cell line (1986) (52)
Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. (2008) (52)
Cloning and Characterization of a Novel Kruppel-associated Box Family Transcriptional Repressor That Interacts with the Retinoblastoma Gene Product, RB* (2000) (50)
MicroRNA-1265 p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk 1 (2015) (49)
Twist is required for muscle template splitting during adult Drosophila myogenesis. (1998) (49)
Conditional Expression of SV40 T-antigen in Mouse Cardiomyocytes Facilitates an Inducible Switch from Proliferation to Differentiation* 210 (2003) (49)
Genetic and epigenetic regulation of cardiomyocytes in development, regeneration and disease (2018) (49)
Activation of the MEF2 transcription factor in skeletal muscles from myotonic mice. (2002) (49)
Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3. (2015) (49)
Gαq and Gα11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme (2003) (48)
Identification of a CArG box-dependent enhancer within the cysteine-rich protein 1 gene that directs expression in arterial but not venous or visceral smooth muscle cells. (2001) (48)
Nkx2-5 Represses Gata1 Gene Expression and Modulates the Cellular Fate of Cardiac Progenitors During Embryogenesis (2011) (48)
Correction of muscular dystrophies by CRISPR gene editing. (2020) (48)
A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR (2006) (47)
Transcription of the myogenic regulatory gene Mef2 in cardiac, somatic, and visceral muscle cell lineages is regulated by a Tinman-dependent core enhancer. (1999) (47)
Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK. (2005) (46)
Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing (2020) (46)
dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. (2003) (46)
Pulmonary hypoplasia in the myogenin null mouse embryo. (2000) (45)
Role of myocyte-specific enhancer-binding factor (MEF-2) in transcriptional regulation of the alpha-cardiac myosin heavy chain gene. (1993) (45)
YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction (2020) (45)
Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. (2014) (44)
State of commitment of prospective neural plate and prospective mesoderm in late gastrula/early neurula stages of avian embryos. (1997) (44)
Regulation of the MEF 2 Family of Transcription Factors by p 38 † (1998) (43)
Molecular control of myogenesis: antagonism between growth and differentiation (2004) (43)
CHAMP, a novel cardiac-specific helicase regulated by MEF2C. (2001) (43)
Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice. (2008) (43)
Evolutionarily conserved promoter region containing CArG*-like elements is crucial for smooth muscle myosin heavy chain gene expression. (1998) (43)
Muscle RING‐finger 2 and 3 maintain striated‐muscle structure and function (2015) (43)
Functional receptors for transforming growth factor-beta are retained by biochemically differentiated C2 myocytes in growth factor-deficient medium containing EGTA but down-regulated during terminal differentiation. (1990) (42)
MEF2B Is a Component of a Smooth Muscle-specific Complex That Binds an A/T-rich Element Important for Smooth Muscle Myosin Heavy Chain Gene Expression* (1998) (42)
Modulating cardiac hypertrophy by manipulating myocardial lipid metabolism? (2002) (42)
Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes. (2011) (41)
A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice. (1998) (41)
Undermining the endothelium by ablation of MAPK-MEF2 signaling. (2004) (41)
Developmental regulation of intermediate filament and actin mRNAs during myogenesis is disrupted by oncogenic ras genes. (1989) (40)
Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells. (2008) (40)
The regulation of acetylcholine receptor expression in mammalian muscle. (1983) (40)
Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish (2017) (40)
Primitive erythropoiesis is regulated by miR-126 via nonhematopoietic Vcam-1+ cells. (2012) (40)
Thoracic skeletal defects in myogenin- and MRF4-deficient mice correlate with early defects in myotome and intercostal musculature. (2000) (39)
KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination (2017) (39)
Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke (2015) (39)
Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi (2013) (39)
Histone Deacetylase 7 (Hdac7) Suppresses Chondrocyte Proliferation and β-Catenin Activity during Endochondral Ossification* (2014) (39)
Modification of proteins with covalent lipids (1988) (39)
DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis (2009) (39)
Genetic regulation of somite formation. (2000) (38)
Myocardin-related transcription factors are required for cardiac development and function. (2015) (38)
Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor (2014) (38)
A ras-dependent pathway abolishes activity of a muscle-specific enhancer upstream from the muscle creatine kinase gene (1989) (38)
Myristoylation, phosphorylation, and subcellular distribution of the 80-kDa protein kinase C substrate in BC3H1 myocytes. (1989) (38)
Knowing in your heart what's right. (1997) (38)
Expression of acetylcholine receptor alpha-subunit mRNA during differentiation of the BC3H1 muscle cell line. (1984) (37)
Correction of Three Prominent Mutations in Mouse and Human Models of Duchenne Muscular Dystrophy by Single-Cut Genome Editing. (2020) (37)
Thymosin β4 and cardiac repair (2010) (36)
Domains outside of the DNA-binding domain impart target gene specificity to myogenin and MRF4 (1991) (36)
Independent Regulatory Elements in the Upstream Region of theDrosophila β3 tubulinGene (βTub60D) Guide Expression in the Dorsal Vessel and the Somatic Muscles (1998) (36)
Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers. (2019) (36)
Inhibition of myogenic differentiation by fibroblast growth factor or type beta transforming growth factor does not require persistent c-myc expression. (1987) (35)
Homeobox genes and muscle patterning (1994) (35)
Regulation of differentiation of the BC3H1 muscle cell line through cAMP-dependent and -independent pathways. (1988) (35)
The majority of cellular fatty acid acylated proteins are localized to the cytoplasmic surface of the plasma membrane. (1987) (34)
A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation. (1999) (34)
Structure, Expression, and Properties of an Atypical Protein Kinase C (PKC3) from Caenorhabditis elegans (1998) (33)
Activation of muscle-specific transcription by myogenic helix-loop-helix proteins. (1992) (33)
Down Syndrome Critical Region-1 Is a Transcriptional Target of Nuclear Factor of Activated T Cells-c1 within the Endocardium during Heart Development* (2007) (32)
A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes (1989) (31)
A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism (2016) (31)
Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106 (2016) (31)
JAK/Stat signaling regulates heart precursor diversification in Drosophila (2011) (31)
MEF 2 : a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation (1999) (31)
Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. (2003) (31)
Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity (2013) (30)
Coactivator control of cardiovascular growth and remodeling. (2006) (30)
Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. (2007) (29)
Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. (2016) (29)
Transcriptome analysis of subcutaneous adipose tissues in beef cattle using 3' digital gene expression-tag profiling. (2012) (29)
Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review. (2016) (29)
Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila (2003) (29)
A New Twist on Twist: Modulation of the NF-kappaB Pathway (2003) (28)
Regulation of intraocular pressure by microRNA cluster miR-143/145 (2017) (28)
Myocardin-related transcription factors are required for skeletal muscle development (2016) (28)
The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy. (2009) (27)
Stac proteins associate with the critical domain for excitation–contraction coupling in the II–III loop of CaV1.1 (2018) (27)
Proto-oncogenes in the regulatory circuit for myogenesis. (1992) (27)
The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming (2021) (27)
Transcriptional analysis of mouse skeletal myofiber diversity and adaptation to endurance exercise (2004) (27)
Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing. (2018) (26)
Toward the correction of muscular dystrophy by gene editing (2021) (26)
Muscle creatine kinase isoenzyme expression in adult human brain. (1990) (26)
Calcineurin-A alpha activation enhances the structure and function of regenerating muscles after myotoxic injury. (2007) (26)
In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse (2019) (25)
Muscle minus myoD. (1998) (25)
Activation of the myogenin promoter during mouse embryogenesis in the absence of positive autoregulation. (1995) (25)
A genetic blueprint for growth and development of the heart. (2002) (25)
Sclerotome-related helix-loop-helix type transcription factor (scleraxis) mRNA is expressed in osteoblasts and its level is enhanced by type-beta transforming growth factor. (1996) (25)
The Multifunctional Ca 2 / Calmodulin-dependent Kinase II ( CaMKII ) Controls Neointima Formation after Carotid Ligation and Vascular Smooth Muscle Cell Proliferation through Cell Cycle Regulation by p 21 * (2011) (24)
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance (2021) (24)
Building a new heart from old parts: stem cell turnover in the aging heart. (2010) (23)
Regulation of cardiac growth and development by SRF and its cofactors. (2002) (23)
Wild-type myoblasts rescue the ability of myogenin-null myoblasts to fuse in vivo. (1997) (23)
NURR1 activation in skeletal muscle controls systemic energy homeostasis (2019) (23)
suppresses smooth muscle gene expression in the heart microRNA-133 a regulates cardiomyocyte proliferation and Material Supplemental (2008) (22)
Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding (2019) (22)
Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. (2017) (22)
Expression, genomic structure and high resolution mapping to 19p13.2 of the human smooth muscle cell calponin gene. (1997) (22)
A novel A/T-rich element mediates ANF gene expression during cardiac myocyte hypertrophy. (1997) (21)
Cullin-3–RING ubiquitin ligase activity is required for striated muscle function in mice (2018) (21)
C-terminal variable AGES domain of Thymosin β4: the molecule's primary contribution in support of post-ischemic cardiac function and repair. (2015) (20)
Expression of the Gene Encoding the LIM Protein CRP2: A Developmental Profile (2002) (20)
Inhibition protects acquired song segments during vocal learning in zebra finches (20)
Analysis of the oligomerization of myogenin and E2A products in vivo using a two-hybrid assay system. (1992) (19)
A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart (2013) (19)
Fibroblast growth factor downregulates expression of a basic helix‐loop‐helix‐type transcription factor, scleraxis, in a chondrocyte‐like cell line, TC6 (1998) (17)
Improving cardiac rhythm with a biological pacemaker (2014) (17)
Scleraxis messenger ribonucleic acid is expressed in C2C12 myoblasts and its level is down‐regulated by bone morphogenetic protein‐2 (BMP2) (1997) (17)
Myogenin is in an evolutionarily conserved linkage group on human chromosome 1q31-q41 and unlinked to other mapped muscle regulatory factor genes. (1990) (17)
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development. (2022) (16)
Experimental approaches to the study of reversible protein fatty acylation in mammalian cells (1990) (16)
The heart-liver metabolic axis: defective communication exacerbates disease (2014) (16)
MED12 regulates a transcriptional network of calcium-handling genes in the heart. (2017) (16)
Making muscle or mitochondria by selective splicing of PGC-1α. (2013) (16)
Neurotrophin–3 knocks heart off Trk (1996) (15)
Things are developing in cardiology. (1997) (14)
Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein (2007) (14)
MCIP 1 Overexpression Suppresses Left Ventricular Remodeling and Sustains Cardiac Function After Myocardial Infarction (2004) (14)
Control of Cardiac Development by the MEF2 Family of Transcription Factors (1999) (14)
The Myogenic Regulatory Factor MRF4 Represses the Cardiac α-Actin Promoter through a Negative-acting N-terminal Protein Domain* (1996) (14)
Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro (2021) (14)
Differential expression of two distinct MyoD genes in Xenopus. (1991) (14)
Transcriptional activity of MEF 2 during mouse embryogenesis monitored with a MEF 2-dependent transgene (1999) (14)
Independent regulatory elements in the upstream region of the Drosophila beta 3 tubulin gene (beta Tub60D) guide expression in the dorsal vessel and the somatic muscles. (1998) (13)
A New Subclass of Helix‐Loop‐Helix Transcription Factors Expressed in Paraxial Mesoderm and Chondrogenic Cell Lineages (1996) (13)
Gene Therapy with the DWORF Micropeptide Attenuates Cardiomyopathy in Mice. (2020) (13)
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing. (2020) (13)
Response to Thum et al. (2011) (12)
Expression of the SM22a Promoter in Transgenic Mice Provides Evidence for Distinct Transcriptional Regulatory Programs in Vascular and Visceral Smooth Muscle Cells (2002) (12)
Assignment1 of fibulin-5 (FBLN5) to human chromosome 14q31 by in situ hybridization and radiation hybrid mapping (1999) (11)
A genetic blueprint for cardiac (2000) (11)
Making matters worse for a broken heart. (2000) (11)
Small open reading frames pack a big punch in cardiac calcium regulation. (2014) (11)
Requirement of myocardinrelated myocardinrelated myocardinrelated transcription factorB factorB factorB for remodeling of branchial arch arteries and smooth muscle differentiation (2005) (11)
Regulatory mechanisms for skeletal muscle differentiation and their relevance to gene expression in the heart. (1992) (11)
CRISPR Modeling and Correction of Cardiovascular Disease. (2022) (11)
Protein fatty acylation: a novel mechanism for association of proteins with membranes and its role in transmembrane regulatory pathways. (1988) (11)
A transcriptional pathway for cardiac development. (1997) (11)
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization (2021) (11)
Identification of a multipotent Twist2-expressing cell population in the adult heart (2018) (11)
Mechanisms of Disease Cardiac Plasticity (2008) (10)
Erratum: A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program (Genes and Development 3: (628-640)) (1990) (10)
An introduction to muscle (2012) (10)
Regulation of synthesis of acetylcholine receptors (1984) (10)
Trout myomaker contains 14 minisatellites and two sequence extensions but retains fusogenic function (2019) (10)
MyoR Modulates Cardiac Conduction by Repressing Gata4 (2014) (9)
Direct reprogramming as a route to cardiac repair. (2021) (9)
Downregulation of the transcription factor scleraxis in brain of patients with Down syndrome. (1999) (9)
Muscle-specific RNA processing continues in the absence of myogenin expression. (1990) (9)
Molecular mechanisms of ventricular hypoplasia. (2002) (9)
MyoD and the paradoxes of myogenesis (1992) (9)
Control of myogenic differentiation by cellular oncogenes (1988) (9)
Sema3a-Nrp1 Signaling Mediates Fast-Twitch Myofiber Specificity of Tw2+ Cells. (2019) (9)
Speci fi c Control of Pancreatic Endocrine band d-Cell Mass by Class IIa Histone Deacetylases HDAC 4 , HDAC 5 , and HDAC 9 (2011) (9)
Nuclear Factor- (cid:1) B Protects the Adult Cardiac Myocyte Against Ischemia-Induced Apoptosis in a Murine Model of Acute Myocardial Infarction (2003) (8)
Characterization of rat skeletal muscle sarcolemma during the development of diabetes (1981) (8)
The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice (2022) (8)
A consolidated AAV system for single-cut CRISPR correction of a common Duchenne muscular dystrophy mutation (2021) (8)
Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro (2020) (8)
Modulating the MicroRNArchitecture of an aging aorta. (2011) (8)
Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease (2023) (8)
Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice (2019) (8)
Hippo in the path to heart repair. (2014) (7)
Protocol for Single-Nucleus Transcriptomics of Diploid and Tetraploid Cardiomyocytes in Murine Hearts (2020) (7)
Coronary artery disease and the MEF2A transcription factor. (2003) (7)
Abstract 4421: SY-5609, an orally available selective CDK7 inhibitor demonstrates broad anti-tumor activity in vivo (2019) (7)
Control of Muscle Metabolism by the Mediator Complex. (2018) (7)
Extensive motor neuron survival in the absence of secondary skeletal muscle fiber formation (1996) (7)
Erratum: Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch (Developmental Cell (2016) 36(3) (316–330) (S1534580716000368)(10.1016/j.devcel.2016.01.002)) (2016) (7)
Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators (2013) (7)
Genetic control of heart development (1997) (7)
Characterization of insulin binding to skeletal muscle sarcolemma during the development of diabetes (1981) (7)
Oligosaccharyltransferase activity is markedly increased during differentiation of a nonfusing myoblast cell line. (1986) (6)
Transcription Factors Controlling Muscle-Specific Gene Expression (1993) (6)
a ! and p Subunits of the Nicotinic Acetylcholine Receptor Contain Covalently Bound Lipid * (2001) (6)
CRISPR/Cas Correction of Muscular Dystrophies. (2021) (6)
Hand Transcription Factors (2002) (6)
Separating the good and evil of cardiac growth by CIB1 and calcineurin. (2010) (6)
Regulation of cold-induced thermogenesis by the RNA binding protein FAM195A (2021) (6)
Purification and cell-free translation of a unique high molecular weight form of the brain isozyme of creatine phosphokinase from mouse. (1982) (5)
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy (2022) (5)
Toward CRISPR Therapies for Cardiomyopathies. (2021) (5)
Reptilian heart development and the molecular basis of cardiac chamber evolution (2009) (5)
A humanized knockin mouse model of Duchenne muscular dystrophy and its correction by CRISPR-Cas9 therapeutic gene editing (2022) (5)
Long-term maintenance of dystrophin expression and resistance to injury of skeletal muscle in gene edited DMD mice (2022) (5)
Secreted MG53 From Striated Muscle Impairs Systemic Insulin Sensitivity (2019) (5)
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy (2022) (5)
A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart (2021) (5)
Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice (2023) (5)
Abstract 474: Myosin Genes Encode a Network of Micrornas that Control Myosin Expression and Myofiber Identity (2008) (5)
Structure, Function, and Biosynthesis of Fatty Acid-Acylated Proteins (1986) (4)
Cardiac Myoediting Attenuates Cardiac Abnormalities in Human and Mouse Models of Duchenne Muscular Dystrophy (2021) (4)
Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. (2016) (4)
Cardiomyopathy Induced −-Adrenergic β Common Genomic Response in Different Mouse Models of Print (2003) (4)
Erratum: Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus (American Journal of Human Genetics (2016) 98(6) (1082–1091) (S000292971630057X) (10.1016/j.ajhg.2016.03.022)) (2016) (4)
On board. (2003) (3)
Circulation Editors and Editorial Board. (2018) (3)
Final general discussion (2006) (3)
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis (2021) (3)
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage–dependent cardiomyopathy (2022) (3)
ATPase and adenylate cyclase distribution in skeletal muscle membranes (1980) (3)
Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. (2016) (3)
Erratum: A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice (Developmental Biology (1998) 199:1 (72-79)) (1998) (3)
Stem Cell Turnover in the Aging Heart (2010) (2)
Abstract 347: Mechanistic Basis of Neonatal Heart Regeneration Revealed by Transcriptome and Histone Modification Profiling (2018) (2)
Abstract 1151: SY-1365, a potent and selective CDK7 inhibitor, exhibits promising anti-tumor activity in multiple preclinical models of aggressive solid tumors (2017) (2)
Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome (2022) (2)
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution (2021) (2)
Erratum to Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest [Cell Reports 9, 26, (2014) 1885-1895] (2015) (2)
Erratum: Expression of the smooth muscle cell calponin gene marks the early cardiac and smooth muscle cell lineages during mouse embryogenesis (Journal of Biological Chemistry (1996) 271 (7095-7103)) (1997) (2)
Considerations for Cardiac CRISPR. (2017) (2)
, N early myogenic lineages . MEF 2 B is a potent transactivator expressed in (1996) (2)
PICKI: A Perinuclear Binding Protein and Substrate for Protein Kinase C Isolated by the Yeast Two-hybrid System (2002) (2)
Discovery and Characterization of Super-Enhancer-Associated Dependencies in Acute Myeloid Leukemia (2014) (2)
Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report. (2002) (2)
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization (2021) (2)
Deconstructing the transcriptional circuitry of development. (2002) (2)
Abstract 189: DWORF: Discovery and Characterization of a Cardiac Micropeptide Encoded in a Putative Long Noncoding RNA (2015) (1)
Oligomerization of Micropeptides that Regulate SERCA (2019) (1)
Abstract 685: Hand2 Is Required for Second Heart Field Development During Cardiogenesis (2007) (1)
Author response: KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination (2017) (1)
The molecules and mechanisms of heart development, disease and regeneration (2014) (1)
Abstract P1-09-08:BCL2L1(BCL-XL) expression and MYC super-enhancer positivity predict sensitivity to the covalent CDK7 inhibitor SY-1365 in triple negative breast cancer (TNBC) cell lines (2018) (1)
Mechanisms of stress-induced cardiac hypertrophy (2012) (1)
Glycogen synthase kinase-3 b mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore (2018) (1)
Genetic knock-down of HDAC 4 improves motor impairment in the R6/2 mouse model of Huntington's disease (2008) (1)
Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation (2013) (1)
Abstract 64: Meis1 Is a Key Regulator of Postnatal Cardiomyocyte Cell Cycle Arrest (2012) (1)
Regulation of Muscle Gene Expression by Histone Deacetylases (2006) (1)
' s personal copy Hand 2 function in second heart fi eld progenitors is essential for cardiogenesis (2011) (1)
Abstract 1143: Targeting the transcriptional kinases CDK12 and CDK13 in breast and ovarian cancer (2017) (1)
MicroRNA Function During Cardiac Hypertrophy (2006) (1)
Genomes and developmental control: Editorial (2004) (1)
Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest. (2015) (1)
The Role Of Histone Deacetylase 9 In Idiopathic Pulmonary Fibrosis (2017) (1)
XII Annual Meeting of the Interuniversity Institute of Myology (2016) (1)
Abstract 40: Discovery and Characterization of the Novel Muscle-Specific Membrane Protein Smco1 (2015) (1)
Biochemistry of Development: Striated Muscle (2013) (1)
Erratum: Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation (Nature Cell Biology (2013) 15 (1035-1044)) (2013) (1)
1001-23 Calmodulin kinase inhibition improves survival in calcineurin transgenic mice (2004) (1)
Abstract 786: Hand Genes in the Mammalian Heart Chamber Formation (2007) (1)
Abstract 4820: Selective CDK7 inhibitors suppress super enhancer-genes, induce massive apoptosis in acute myeloid leukemia and demonstrate durablein vivoefficacy (2016) (1)
Entrepreneurialism in the Translational Biologic Sciences (2018) (1)
Targeting Transcriptional Dependency in Acute Myeloid Leukemia (AML) with a Covalent Inhibitor of Transcriptional Kinase CDK7 (2015) (1)
raxis : a basic helix-loop-helix protein g mouse embryogenesis (1995) (0)
Abstract 1571: TAZ Functions as a Coactivator of GATA Family Proteins, and Notch Signaling Represses GATA Activity through TAZ (2006) (0)
O3.3Covalent CDK-7 inhibitors as new anti-cancer agents (2015) (0)
Abstract 1568: Mef2c Downstream Targets Direct Cardiac Morphogenesis (2006) (0)
Protein kinases C and D target class II histone deacetylases to control pathological cardiac gene expression (2004) (0)
730. Permanent Correction of Diverse Muscular Dystrophy Mutations in Human Cardiomyocytes by Myoediting (2016) (0)
Abstract 2570: Inhibition of Basal CaMKII Activity Resets ICa and E-C Coupling and Alters Cardiac Response to Beta-adrenergic Activation (2009) (0)
Novel serotonergic modulators of cardiac hypertrophy (2004) (0)
Erratum: A hypomorphic Myogenin allele reveals distinct Myogenin expression levels required for viability, skeletal muscle development, and sternum formation (Developmental Biology (1999) 208:1 (44-55)) (1999) (0)
Specificity of protein fatty acid acylation (1985) (0)
Abstract 183: Cardiac Specific Deletion of Tbx5 Causes Left Ventricular Diastolic Dysfunction that can be Rescued by Increased Serca2a Activity (2006) (0)
chapter 10 – Cardiac Development and Congenital Heart Disease (2004) (0)
Passing the torch (2006) (0)
Abstract 18209: The Effect of CaMKIIdelta Knockout on Cardiac E-C Coupling in Heart Failure (2010) (0)
Abstract P183: Cardiac Deletion of CaMKII Delta and Gamma Protects Against Heart Failure Despite Activation of Calcineurin Signaling (2011) (0)
Modeling heart failure for therapeutic screens in engineered human myocardium (2018) (0)
Regulation of Skeletal Muscle Sarcomere Integrity and Postnatal Muscle Function by Mef2c (cid:1) (2007) (0)
Abstract P244: Transcriptional Regulation of Cardiac Gene Expression by Med13 Alters Global Energy Balance (2011) (0)
OE-336 TAZ Functions as a Coactivator of GATA Family Proteins, and Notch Signaling Represses GATA Activity through TAZ(Development and differentiation(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society) (2008) (0)
Histone Deacetylases in Cardiovascular Development and Disease (2010) (0)
The Biology of Lipid-Containing Membrane Proteins (1990) (0)
Abstract P004: Cardiac Regeneration in Neonatal Mice Following Ischemic Injury (2011) (0)
Evolution of muscle cell diversity through modular enhancers (1997) (0)
Angiotensin II Stimulates Histone Deacetylase 5 Phosphorylation and Nuclear Export via AT1‐PKC‐PKD Pathway Leading to Vascular Smooth Muscle Cell Hypertrophy (2007) (0)
The molecules and mechanisms of heart development, disease and regeneration (2014) (0)
A Message of Gratitude to the ad Hoc Reviewers (1999) (0)
Reprogramming of cardiac cell fate as a therapeutic strategy for ischemic heart disease. (2023) (0)
Fatty acid acylation of the α- and β-subunits of the acetylcholine receptor is required for subunit assembly in muscle cells (1984) (0)
Transforming growth factor f8represses theactions ofmyogenin through amechanism independent ofDNA binding (1991) (0)
Abstract EC102: RBPMS, An RNA-binding Protein That Mediates Cardiomyocyte Binucleation And Cardiovascular Development (2022) (0)
Abstract B05: MicroRNA-206 drives rhabdomyosarcoma differentiation through downregulation of PAX7 (2016) (0)
Profiles in Cardiovascular Science (2010) (0)
Conference Calendar (2010) (0)
Abstract P302: CaMKII Is Not Critical for Ischemia/Reperfusion Injury (2011) (0)
A novel phospho-acceptor site controls nuclear import of histone deacetylase 9, a negative regulator of pathological cardiac hypertrophy (2004) (0)
Cardiac Reprogramming: Toward a Total Eclipse of the Failing Heart. (2023) (0)
Novartis Foundation Symposium: Introduction (2006) (0)
Abstract 3201: Protein Kinase D1 is Required for Pathological Cardiac Remodeling (2009) (0)
Transcriptional control of cardiovascular development (1997) (0)
Conference Calendar (2010) (0)
Abstract 3165: Stroma-immune landscape in lymphoma: new mechanisms of immunosuppression and therapeutic targeting (2021) (0)
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing (2020) (0)
Abstract 313: Twist Contributes to Cardiomyocyte Renewal and is Required for Maintenance of Adult Cardiac Function (2015) (0)
Inhibition of histondeacetylasesom treatment of cardiac hypertrophy (2002) (0)
Leaders in Cardiovascular Research: Eric Olson. (2020) (0)
Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Gamma Is the Main Integrator of Calcium Signaling at Fertilization in the Mouse. (2009) (0)
079DWORF overexpression prevents heart failure in an experimental mouse model of dilated cardiomyopathy (2017) (0)
REGULATION OF RIGHT VENTRICLE AND AORTIC ARCH FORMATION BY THE bHLH PROTEIN, dHAND • 145 (1997) (0)
2008 Distinguished Scientist Lecture—MicroRNA Control of Heart Disease: From New Biology to New Therapeutics (2008) (0)
Control of Muscle Growth and Remodeling by Calcium‐Dependent Transcription (2006) (0)
P2570Synergistic activation of the cardiac enhancer landscape during reprogramming (2019) (0)
Tissues & Organs | Biochemistry of Development: Striated Muscle (2021) (0)
Abstract 339: DWORF: a Novel Cardiac Micropeptide That Enhances SERCA Activity and Cardiomyocyte Contractility (2015) (0)
responsiveness of smooth muscle cells to injury MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics Material Supplemental (2010) (0)
Abstract 12931: Myocardial Regeneration in End-stage Heart Failure After Left Ventricular Unloading (2020) (0)
Author response: The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy (2018) (0)
Conference Calendar (2011) (0)
Abstract 20566: Dissecting How Newly Discovered SERCA2-Regulating Micropeptides Control Heart Function and Disease (2017) (0)
CRISPR-EDITING THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY. (2023) (0)
Reviewers of Volume 7 (1980) (0)
Abstract 1118: Novel Lentiviral Vectors Bearing the Cardiac-Specific Promoter of the Sodium-Calcium Exchanger (NCX1) Report Cardiogenic Differentiation in Stem Cells (2007) (0)
Ca 2 +-calcineurin-NFAT signaling plays a major role in promoting pathological cardiac hypertrophy (2010) (0)
Single-Swap Editing for the Correction of Common Duchenne Muscular Dystrophy Mutations (2023) (0)
Abstract 1104: Myosin storage myopathy resulting from the loss of Muscle RING Finger 1 and 3 (2007) (0)
IS007 THE ENDOTHELIN-1 (ET-1)-HAND PATHWAY REGULATES CRANIAL/CARDIAC NEURAL CREST DEVELOPMENT (1997) (0)
Abstract 16602: Mitolamban is a Novel Cardiac-Enriched Mitochondrial Microprotein That Regulates Respiratory Complex III (2020) (0)
CRISPR-Cas9 Correction of Duchenne Muscular Dystrophy in Mice by a Self-Complementary AAV Delivery System. (2023) (0)
Abstract 784: Nkx2 5 Is Transcriptional Activator Of Etsrp71, Which Promotes An Endocardial Fate In The Developing Heart (2007) (0)
Receptor Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a (2009) (0)
Abstract 3837: Super-enhancers define breast cancer subclasses and identify novel tumor cell vulnerabilities (2015) (0)
Abstract 103: Mechanistic Interplay Between Cardioprotection And Heart Regeneration Mediated By The ER-bound Transcription Factor Nrf1 (2021) (0)
Redox-Dependent Transcriptional Regulation Control of Cardiac Growth by Histone Acetylation/Deacetylation Excitation-Transcription Coupling in Vascular Smooth Muscle (2005) (0)
STARS is a Mediator of MEF2 Signaling and SRF Activity During Cardiac Remodeling (2007) (0)
Abstract 356: CaMKII Cytoplasmic and Nuclear Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses (2006) (0)
Hdac4- and HDAC5-dependent regulation of gene expression in the heart (2000) (0)
Abstract 309: Two SoxD Family Transcription Factors Influence Heart Function at Baseline and After Cardiac Overload (2013) (0)
6 HBPRCA RD WRIGHT LECTURE: MICRORNAS AND THE FINE TUNING OF CARDIOVASCULAR HEALTH (2012) (0)
Abstract 327: Cardiac Regulation of Metabolic Homeostasis by Med13 (2013) (0)
Functional study of Let-7 microRNA family in choroidal neovascularization (2014) (0)
Abstract 3085: SY-1425 (tamibarotene), a selective RARα agonist, shows synergistic anti-tumor activity with hypomethylating agents in a biomarker selected subset of AML (2017) (0)
Abstract P4-04-02: Epigenomic analysis of cancer stem cells (CSCs) from triple-negative breast cancer (TNBC) reveals p63 and p73 as core metastasis drivers (2020) (0)
Development of Slow Muscle Fibers Maintenance but Not Embryonic Calcineurin Is Necessary for the (2005) (0)
Abstract P2006: S100A1 And STRIT1 Redundantly Governs Responsiveness Of The Heart To Hemodynamic Stress Via Modulation Of SERCA2a Activity (2022) (0)
Mechanisms of normal cardiovascular growth and development (2005) (0)
MiR-145: A Role In The Development Of Pulmonary Arterial Hypertension (2012) (0)
Heart making and heart breaking: The molecular circuitry of cardiac development, disease and regeneration (2011) (0)
Abstract 15527: Histone Deacetylase 9 (HDAC9) is an Endogenous Inhibitor of Adipocyte Differentiation: Role in Diet-Induced Obesity (2010) (0)
Abstract 6193: TWIST2 promotes tumor progression and represses myogenic differentiation in rhabdomyosarcoma (2022) (0)
Molecular Mechanism of Cardiac Development and Hypertrophy (Tentative) (1998) (0)
PNAS Plus Significance Statements (2015) (0)
Abstract 281: Differential Regulation of Histone Deacetylase 4 by CaM Kinase II and Protein Kinase A in Response to Cardiac Beta-Adrenergic Signaling (2007) (0)
INSULIN REGULATES ASTROCYTIC GLUCOSE HANDLING THROUGH COOPERATION WITH INSULIN-LIKE GROWTH FACTOR I (2016) (0)
Abstract 1187: Discovery of new AML and MDS patient subsets sensitive to the highly selective RARα agonist SY-1425 (tamibarotene) through super-enhancer analysis (2016) (0)
Abstract 3737: Redundant Roles of CaM Kinase II{delta} and {gamma} in Cardiac Hypertrophic Signaling (2009) (0)
Muscle Development and Differentiation (2006) (0)
Abstract 1991: Myozap, a Novel Cardiac Protein, is a Component of the Intercalated Disc and Activates SRF-dependent Signaling (2009) (0)
Abstract 705: Synergistic Activation of the Cardiac Enhancer Landscape During Cardiac Reprogramming (2019) (0)
Abstract 5305: Knockout of the {delta} Isoform of CaMKII does not Negatively Influence Cardiomyocyte Excitation-Contraction Coupling in Mice (2008) (0)
Abstract 14741: CaMKII{delta} Controls Neointimal Formation After Carotid Ligation and Vascular Smooth Muscle Cells Proliferation Through Regulation of the Akt/mdm2 Pathway (2010) (0)
Role of Thymosin β-4 During Cardiac Development and Myocardial Cell Survival (2009) (0)
Abstract 335: Regulation of Muscle Contractility by a Family of SERCA-Inhibitory Micropeptides (2015) (0)
Control of Heart Development by Transcriptional Coactivators and Corepressors(Cardiovascular Development, The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Abstract IA13: MicroRNA control of muscle development and disease: from new biology to new therapeutics (2012) (0)
Abstract 5273: Nkx2-5 Transactivates The Ets-related Protein 71 Gene And Specify An Endothelial/endocardial Fate Of The Developing Heart (2008) (0)
Requirement of Mef2 Transcriptional Factors in Maintaining Vascular Integrity (2010) (0)
Abstract 120: Genome-wide DNA Methylation Analysis Reveals Dynamic Changes in the Cardiac Methylome During Post-natal Heart Development (2014) (0)
Abstract 13073: Epicardial YAP/TAZ Regulate an Immune Suppressive Response Following Myocardial Infarction (2015) (0)
302MiR-126-5p promotes endothelial cell proliferation and limits lesion formation during atherosclerosis by suppressing Dlk1 (2014) (0)
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis (2018) (0)
Identification of a microRNA that activates the expression of the beta myosin heavy chain (2007) (0)
Regulator of Adipogenic Differentiation Histone Deacetylase 9 Is a Negative Cell Biology (2013) (0)
Role of microRNAs in Retinal Angiogenesis (2011) (0)
Abstract P493: Histone Reader PHF7 Cooperates With The SWI/SNF Complex At Cardiac Super Enhancers To Promote Direct Reprogramming (2021) (0)
Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation (2017) (0)
Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression (2013) (0)
HDAC4 is necessary for satellite cell differentiation and muscle regeneration (2014) (0)
Abstract 725: A Transcriptional Basis for Neonatal Heart Regeneration at Single Cell Resolution (2019) (0)
O127 Increased Serca2a activity can rescue ventricular diastolic dysfunction which is caused by deletion of Tbx5 (2008) (0)
prolonged thyroid hormone treatment Functional and metabolic adaptation of the heart to (2006) (0)
Inhibition of histone deacetylase for the treatment of cardiac hypertrophy. (2002) (0)
A critical period of vulnerability to hyperactive Gq signaling revealed by inducible and heart-specific expression of Gq∗ in transgenic mice (1999) (0)
Abstract 147: Screening for Developmental and Injury-Induced Genes That Facilitate Heart Regeneration (2019) (0)
Abstract 958: Reversibility of Calcineurin-Dependent Ventricular Remodeling (2006) (0)
Suppression of proliferation I hypertrophy by CHAMP, a ca RNA helicase (2016) (0)
PE-210 TRPC6 Fulfills a Calcineurin Signaling Circuit During Pathological Cardiac Remodeling(Cardiac hypertrophy, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
Regulation of myogenic helix loop helix gene transcription by thyroid hormone Identification of the thyroid hormone and retinoid X receptor heterodimeric binding site (1994) (0)
Abstract 897: Etsrp71 is a Novel Downstream Target of Nkx2 5 which Promotes Cardiac Morphogenesis (2006) (0)
423 Genome wide expression profiling of NFAT transcriptional activity in a ventricular muscle cell line identifies GATA4 as an NFAT target gene in a feedforward mechanism driving cardiomyocyte hypertrophy (2006) (0)
TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma (2023) (0)
Abstract 17596: Mir-126-5p Promotes Endothelial Cell Proliferation and Limits Lesion Formation During Atherosclerosis by Suppressing Dlk1 (2013) (0)
S100A1 & STRIT1 redundantly governs responsiveness of the heart to hemodynamic stress via modulation of SERCA2A activity (2022) (0)
CaMKII isoforms and calcineurin (2014) (0)
Cardiac Development: Toward a Molecular Basis for Congenital Heart Disease (2007) (0)
Conference Calendar (2010) (0)
Abstract 2644: SY-1425, a selective RARα agonist, induces high levels of CD38 expression in RARA-high AML tumors creating a susceptibility to anti-CD38 therapeutic antibody treatment (2017) (0)
Minireview Modules for Organ Assembly (1997) (0)
Abstract 1241: Nkx2 5 Regulates Cell Fate Decisions in the Developing Embryo (2006) (0)
Earlyreperfusionofischemiccardiactissueremainsthemosteffectiveinterventionforimprovingclinicalout- comefollowingmyocardialinfarction.However,abnormalincreasesinintracellularCa 2+ duringmyocardial reperfusioncancausecardiomyocytedeathandconsequentlossofcardiacfunction,referredtoasischemia/ reperfusio (2012) (0)
Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. (2023) (0)
165 HDAC1 and HDAC2 regulate homeostasis and tumorigenesis of postnatal epidermis (2018) (0)
Abstract 14745: The Histone Reader PHF7 Cooperates With the SWI/SNF Complex at Cardiac Super Enhancers to Promote Direct Cardiac Reprogramming (2020) (0)
Protein kinase‐D1 overexpression in mice prevents lipid‐induced insulin resistance and cardiomyopathy by upregulation of glucose uptake (2011) (0)
Abstract 2212: Super-enhancer landscapes specify molecular subtypes and novel targets in acute myeloid leukemia (2015) (0)
A MOUSE MODEL FOR THE DIGEORGE PHENOTYPE ASSOCIATED WITH ABNORMALITIES OF THEHAND GENES. • 212 (1996) (0)
Abstract 9576: A Nuclear Receptor-microRNA Circuit Links Control of Muscle Fiber Type to Energy Metabolism (2012) (0)
Regulation of acetylcholine receptor expression by subunit assembly (1984) (0)
Stac Proteins Associate with the Domain of the Ca V 1.1 II-III Loop Critical for EC Coupling (2018) (0)
Abstract 3868: Protein Kinase A Decreases MEF2-Activity by Limited Proteolysis of Histone Deacetylase 4 (2009) (0)
Abstract 011: Transcriptional Basis Of Epicardial Progenitor Cell Activation During Heart Development, Regeneration And Repair (2013) (0)
The Heart of the Matter (2005) (0)
MRTF-A, a rho-dependent co-activator of SRF, mediates mechanical stress-induced hypertrophic gene activation (2008) (0)
PE-305 The actin-binding Protein STARS is a Cytoskeletal Intermediary between MEF2 and SRF during Cardiac Remodeling(Cardiomyopathy, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
Abstract P2068: The Nuclear Transcription Factor Y Controls Cell-cycle And Metabolic Gene Transcription During Cardiac Development (2022) (0)
Histone deacetylases 1 & 2 control adipogenesis (2008) (0)
Double-Positive Thymocytes and TCR Signaling in CD4/CD8 Histone Deacetylase 7 Regulates Cell Survival (2011) (0)

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