Paolo Bernardi
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Italian pathologist
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Biology
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Pathology
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Biology
Paolo Bernardi's Degrees
- Doctorate Medicine University of Milan
- PhD Pathology University of Milan
Why Is Paolo Bernardi Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paolo Bernardi is an Italian professor of pathology who has an h-index of 96 and 34,893 citations of his works. He works at University of Padua in Italy. External links Paolo Bernardi
Paolo Bernardi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mitochondrial transport of cations: channels, exchangers, and permeability transition. (1999) (1457)
- Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis (2005) (1072)
- The mitochondrial permeability transition (2022) (1031)
- Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria (2008) (955)
- Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D* (2005) (822)
- Dimers of mitochondrial ATP synthase form the permeability transition pore (2013) (814)
- Mitochondria and cell death (1999) (685)
- Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. (1999) (658)
- Opening of the Mitochondrial Permeability Transition Pore Causes Depletion of Mitochondrial and Cytosolic NAD+and Is a Causative Event in the Death of Myocytes in Postischemic Reperfusion of the Heart* (2001) (648)
- The mitochondrial permeability transition from in vitro artifact to disease target (2006) (606)
- Mitochondria as all‐round players of the calcium game (2000) (602)
- Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane (1994) (570)
- High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening (2006) (568)
- Modulation of the Mitochondrial Permeability Transition Pore by Pyridine Nucleotides and Dithiol Oxidation at Two Separate Sites (*) (1996) (537)
- The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents. (1994) (523)
- The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis (2007) (494)
- Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration (2010) (484)
- The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal (1996) (476)
- Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency (2003) (470)
- Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel (*) (1996) (467)
- Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis. (2011) (461)
- A mitochondrial perspective on cell death. (2001) (443)
- The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology. (2015) (442)
- A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis (2002) (436)
- Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations. (1992) (435)
- Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization. (1992) (430)
- The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. (1996) (424)
- The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection (2015) (389)
- The Mitochondrial Permeability Transition, Release of Cytochrome c and Cell Death (2001) (370)
- Mitochondria and cell death. Mechanistic aspects and methodological issues. (1999) (366)
- Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole. (2006) (352)
- Regulation of the Permeability Transition Pore in Skeletal Muscle Mitochondria (1998) (333)
- The mitochondrial permeability transition pore: a mystery solved? (2013) (312)
- Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria. (1993) (309)
- Arachidonic Acid Causes Cell Death through the Mitochondrial Permeability Transition (2000) (272)
- Cyclophilin D Modulates Mitochondrial F0F1-ATP Synthase by Interacting with the Lateral Stalk of the Complex* (2009) (269)
- Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels (2008) (267)
- A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore* (1998) (252)
- The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. (1996) (235)
- Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. II. The minimal requirements for pore induction underscore a key role for transmembrane electrical potential, matrix pH, and matrix Ca2+. (1993) (232)
- Properties of the permeability transition in VDAC1(-/-) mitochondria. (2006) (229)
- Modulation of the mitochondrial megachannel by divalent cations and protons. (1992) (220)
- Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition (2009) (219)
- Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A. (1994) (214)
- The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase (2012) (211)
- Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies (2008) (204)
- Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis (2007) (197)
- Calcium and cell death: the mitochondrial connection. (2007) (192)
- Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins (2007) (187)
- On the Voltage Dependence of the Mitochondrial Permeability Transition Pore (1997) (184)
- Signal transduction to the permeability transition pore (2010) (184)
- Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes. (1981) (182)
- Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. I. Evidence for two separate Me2+ binding sites with opposing effects on the pore open probability. (1993) (181)
- Bupivacaine Myotoxicity Is Mediated by Mitochondria* (2002) (181)
- Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation. (1993) (174)
- Arachidonic Acid Released by Phospholipase A2 Activation Triggers Ca2+-dependent Apoptosis through the Mitochondrial Pathway* (2004) (170)
- Mitochondria and cardioprotection (2007) (170)
- Mitochondrial function as a determinant of recovery or death in cell response to injury (1998) (169)
- Cyclophilin D in mitochondrial pathophysiology. (2010) (167)
- Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation* (2008) (166)
- Commitment to Apoptosis by GD3 Ganglioside Depends on Opening of the Mitochondrial Permeability Transition Pore* (1999) (165)
- The permeability transition pore as a Ca2+ release channel: New answers to an old question (2012) (164)
- p66Shc-generated Oxidative Signal Promotes Fat Accumulation* (2008) (158)
- Progress on the Mitochondrial Permeability Transition Pore: Regulation by Complex I and Ubiquinone Analogs (1999) (152)
- Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane Does Not Involve the Peripheral Benzodiazepine Receptor (Translocator Protein of 18 kDa (TSPO))* (2014) (151)
- BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore (2002) (149)
- Three Classes of Ubiquinone Analogs Regulate the Mitochondrial Permeability Transition Pore through a Common Site* (2000) (142)
- On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. (1995) (142)
- Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition. (2005) (139)
- Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition*♦ (2014) (138)
- Calcium and regulation of the mitochondrial permeability transition. (2017) (136)
- Ca2+ binding to F‐ATP synthase β subunit triggers the mitochondrial permeability transition (2017) (131)
- A CaPful of mechanisms regulating the mitochondrial permeability transition. (2009) (130)
- The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells (2003) (125)
- The mitochondrial permeability transition from yeast to mammals (2010) (124)
- Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury (2009) (123)
- The mitochondrial permeability transition pore and cyclophilin D in cardioprotection. (2011) (121)
- The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1−/− myopathic mice (2009) (120)
- Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore (2019) (120)
- EM.P.5.04 Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice (2009) (115)
- Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondria (1991) (113)
- Effects of fatty acids on mitochondria: implications for cell death. (2002) (112)
- The effects of idebenone on mitochondrial bioenergetics (2012) (112)
- The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore* (2003) (111)
- UCPs — unlikely calcium porters (2008) (102)
- Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. (2012) (102)
- Mitochondrial targeting of the p13II protein coded by the x-II ORF of human T-cell leukemia/lymphotropic virus type I (HTLV-I) (1999) (101)
- From ATP to PTP and Back: A Dual Function for the Mitochondrial ATP Synthase. (2015) (101)
- Chloromethyltetramethylrosamine (Mitotracker OrangeTM) Induces the Mitochondrial Permeability Transition and Inhibits Respiratory Complex I (1999) (99)
- Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral Benzodiazepine Receptor)* (2010) (99)
- Calcium and reactive oxygen species in regulation of the mitochondrial permeability transition and of programmed cell death in yeast. (2016) (97)
- Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases (2017) (94)
- Selective inhibition of the mitochondrial permeability transition pore at the oxidation‐reduction sensitive dithiol by monobromobimane (1995) (94)
- Shedding light on the mitochondrial permeability transition. (2011) (93)
- Induction of the mitochondrial permeability transition by N-ethylmaleimide depends on secondary oxidation of critical thiol groups. Potentiation by copper-ortho-phenanthroline without dimerization of the adenine nucleotide translocase. (1998) (91)
- The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function (2018) (91)
- Imaging the mitochondrial permeability transition pore in intact cells (1998) (90)
- Singlet Oxygen Produced by Photodynamic Action Causes Inactivation of the Mitochondrial Permeability Transition Pore* (1997) (90)
- Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons (2011) (90)
- Regulation of the Mitochondrial Permeability Transition Pore by Ubiquinone Analogs. A Progress Report (2002) (88)
- Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury. (2001) (87)
- Snake Phospholipase A2 Neurotoxins Enter Neurons, Bind Specifically to Mitochondria, and Open Their Transition Pores* (2008) (87)
- The mitochondrial permeability transition pore and its adaptive responses in tumor cells (2014) (85)
- Genetic Dissection of the Permeability Transition Pore (2005) (82)
- Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate (2006) (80)
- The unique histidine in OSCP subunit of F‐ATP synthase mediates inhibition of the permeability transition pore by acidic pH (2018) (78)
- Mitochondria and reperfusion injury. The role of permeability transition. (2003) (78)
- Mitochondrial energy dissipation by fatty acids. Mechanisms and implications for cell death. (2002) (78)
- Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells (2014) (76)
- The Mitochondrial Effects of Small Organic Ligands of BCL-2 (2006) (75)
- Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels* (2009) (74)
- Pathophysiology of mitochondrial volume homeostasis: potassium transport and permeability transition. (2009) (72)
- Dysfunction of Mitochondria and Sarcoplasmic Reticulum in the Pathogenesis of Collagen VI Muscular Dystrophies (2008) (72)
- Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1. (2017) (70)
- Desensitization of the Permeability Transition Pore by Cyclosporin A Prevents Activation of the Mitochondrial Apoptotic Pathway and Liver Damage by Tumor Necrosis Factor-α* (2004) (70)
- Regulation of Ca2+ efflux in rat liver mitochondria. Role of membrane potential. (1983) (68)
- Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death (2012) (67)
- F-ATPase of Drosophila melanogaster Forms 53-Picosiemen (53-pS) Channels Responsible for Mitochondrial Ca2+-induced Ca2+ Release* (2014) (65)
- Mitochondrial dysfunction and defective autophagy in the pathogenesis of collagen VI muscular dystrophies. (2013) (65)
- Mitochondrial Alterations Induced by the p13II Protein of Human T-cell Leukemia Virus Type 1 (2002) (64)
- Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells (2014) (61)
- Mitochondria as functional targets of proteins coded by human tumor viruses. (2005) (61)
- Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo. (2014) (61)
- Electroneutral H+-K+ exchange in liver mitochondria. Regulation by membrane potential. (1983) (60)
- Properties of Ca2+ Transport in Mitochondria of Drosophila melanogaster* (2011) (60)
- Pathways for Ca2+ efflux in heart and liver mitochondria. (1987) (59)
- Mitochondria Are Direct Targets of the Lipoxygenase Inhibitor MK886 (2002) (58)
- Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene (2003) (58)
- Induction of the permeability transition pore in cells depleted of mitochondrial DNA. (2012) (58)
- The mitochondrial permeability transition pore. (2007) (57)
- Pathway for uncoupler-induced calcium efflux in rat liver mitochondria: inhibition by ruthenium red. (1984) (57)
- Tissue‐specific modulation of the mitochondrial calcium uniporter by magnesium ions (1985) (56)
- Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D (2008) (54)
- SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I (2013) (54)
- Antamanide, a Derivative of Amanita phalloides, Is a Novel Inhibitor of the Mitochondrial Permeability Transition Pore (2011) (54)
- Chemical Modification of Arginines by 2,3-Butanedione and Phenylglyoxal Causes Closure of the Mitochondrial Permeability Transition Pore* (1998) (54)
- Manganese stimulates calcium flux through the mitochondrial uniporter. (1985) (53)
- Reduced mitochondrial Ca2+ transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase (2015) (53)
- High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits (2018) (53)
- Peptide-based carbon nanotubes for mitochondrial targeting. (2013) (52)
- Mitochondria and reperfusion injury (2003) (52)
- Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants. (2014) (50)
- The Oligomycin-Sensitivity Conferring Protein of Mitochondrial ATP Synthase: Emerging New Roles in Mitochondrial Pathophysiology (2014) (50)
- NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models. (2014) (50)
- Mechanistic aspects and methodological issues (1999) (49)
- Therapy of collagen VI-related myopathies (Bethlem and Ullrich) (2008) (49)
- F‐ATP synthase and the permeability transition pore: fewer doubts, more certainties (2019) (49)
- Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface (2013) (49)
- Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo (2018) (48)
- Cyclosporine A in Ullrich Congenital Muscular Dystrophy: Long-Term Results (2011) (48)
- Mitochondria in muscle cell death (1999) (48)
- Modulation of mitochondrial K(+) permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1. (2009) (47)
- Yessotoxin, a shellfish biotoxin, is a potent inducer of the permeability transition in isolated mitochondria and intact cells. (2004) (47)
- Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection. (2020) (47)
- A membrane potential‐modulated pathway for Ca2+ efflux in rat liver mitochondria (1982) (45)
- p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis (2007) (45)
- The Pathophysiology of LETM1 (2012) (44)
- Transcriptomic Analysis of Single Isolated Myofibers Identifies miR-27a-3p and miR-142-3p as Regulators of Metabolism in Skeletal Muscle. (2019) (44)
- Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress. Unmasking pore-regulating external thiols. (2009) (43)
- The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents? (2006) (43)
- p66Shc, mitochondria, and the generation of reactive oxygen species. (2013) (42)
- LETM1 in mitochondrial cation transport (2014) (41)
- Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter (2017) (41)
- Why F-ATP Synthase Remains a Strong Candidate as the Mitochondrial Permeability Transition Pore (2018) (39)
- A GENERAL AND CONVENIENT PROCEDURE FOR THE SYNTHESIS OF N-ALKYLARYLAMINES AND N-ALKYLHETEROARYLAMINES BY ELECTROPHILIC AMINATION OF CUPRATES WITH N-AL KYLHYDROXYLAMINES (1999) (39)
- Gene status in HER2 equivocal breast carcinomas: impact of distinct recommendations and contribution of a polymerase chain reaction-based method. (2014) (39)
- Discovery, Synthesis, and Optimization of Diarylisoxazole‐3‐carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore (2015) (39)
- Erratum: The mitochondrial permeability transition from in vitro artifact to disease target (FEBS Journal (2006) 273 (2077-2099)) (2006) (39)
- Altered threshold of the mitochondrial permeability transition pore in Ullrich congenital muscular dystrophy. (2008) (39)
- Monoamine oxidase inhibition prevents mitochondrial dysfunction and apoptosis in myoblasts from patients with collagen VI myopathies (2014) (38)
- Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy (2017) (38)
- Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca2+‐dependent death of cancer cells (2020) (38)
- Perspectives on the mitochondrial permeability transition (1998) (38)
- The K+ conductance of the inner mitochondrial membrane. A study of the inducible uniport for monovalent cations. (1991) (38)
- Modification of Permeability Transition Pore Arginine(s) by Phenylglyoxal Derivatives in Isolated Mitochondria and Mammalian Cells (2005) (38)
- Cytotoxicity of a mitochondriotropic quercetin derivative: mechanisms. (2012) (36)
- Activation of latent K+ uniport in mitochondria treated with the ionophore A23187. (1989) (36)
- The mitochondrial permeability transition: Recent progress and open questions (2021) (36)
- Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-XL- and PKB/AKT-independent fashion (2004) (36)
- Mitochondrial ion channels as targets for cardioprotection (2020) (35)
- Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal (2018) (34)
- Implications of the generation of reactive oxygen species by photoactivated calcein for mitochondrial studies. (2000) (34)
- N‐Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore (2016) (34)
- The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis (2009) (34)
- Mechanisms for Ca2+-dependent permeability transition in mitochondria (2020) (33)
- Novel Mitochondrial Creatine Transport Activity (2002) (33)
- Ligand-selective Modulation of the Permeability Transition Pore by Arginine Modification (2002) (31)
- Chloromethyltetramethylrosamine (Mitotracker Orange) induces the mitochondrial permeability transition and inhibits respiratory complex I. Implications for the mechanism of cytochrome c release. (1999) (30)
- UCP4C mediates uncoupled respiration in larvae of Drosophila melanogaster (2014) (29)
- Modulation of Mitochondrial Permeability Transition in Ischemia-Reperfusion Injury of the Heart. Advantages and Limitations. (2015) (29)
- Dopamine Oxidation Products as Mitochondrial Endotoxins, a Potential Molecular Mechanism for Preferential Neurodegeneration in Parkinson's Disease. (2018) (28)
- Destabilization of the Outer and Inner Mitochondrial Membranes by Core and Linker Histones (2012) (28)
- Changes in Muscle Cell Metabolism and Mechanotransduction Are Associated with Myopathic Phenotype in a Mouse Model of Collagen VI Deficiency (2013) (28)
- Reciprocal Relationships between the Resistance to Stresses and Cellular Aging a (1998) (27)
- Mitochondrial Ca2+ transport and permeability transition in zebrafish (Danio rerio). (2010) (27)
- Arg-8 of yeast subunit e contributes to the stability of F-ATP synthase dimers and to the generation of the full-conductance mitochondrial megachannel (2019) (27)
- Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase (2021) (27)
- On the nature of Pi‐induced, Mg2+‐prevented Ca2+ release in rat liver mitochondria (1982) (27)
- Commentary: SPG7 is an essential and conserved component of the mitochondrial permeability transition pore (2015) (26)
- Hepatic progenitor cells express SerpinB3 (2014) (26)
- OSCP subunit of mitochondrial ATP synthase: role in regulation of enzyme function and of its transition to a pore (2018) (26)
- Forty years later: Mitochondria as therapeutic targets in muscle diseases. (2016) (25)
- Mitochondrial respiratory states and rates (2019) (25)
- Hexokinase 2 displacement from mitochondria-associated membranes prompts Ca2+-dependent death of cancer cells (2019) (25)
- Inhibition of the mitochondrial cyclosporin A‐sensitive permeability transition pore by the arginine reagent phenylglyoxal (1997) (25)
- ΔpH Induced Calcium Fluxes in Rat Liver Mitochondria (1979) (25)
- A novel class of cardioprotective small-molecule PTP inhibitors. (2019) (24)
- Mitochondrial Alterations Induced by the p13 Protein of Human T-cell Leukemia Virus Type 1 CRITICAL ROLE OF ARGININE RESIDUES* (2002) (24)
- Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels (2009) (24)
- Species-specific modulation of the mitochondrial permeability transition by norbormide. (2005) (23)
- Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction. (2004) (23)
- Melanocytes—A Novel Tool to Study Mitochondrial Dysfunction in Duchenne Muscular Dystrophy (2012) (23)
- ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties (2018) (23)
- A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure (2011) (22)
- The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore. (2020) (22)
- The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects. (2018) (21)
- A gated pathway for electrophoretic Na+ fluxes in rat liver mitochondria. Regulation by surface Mg2+. (1990) (20)
- Inhibition by Sr2+ of specific mitochondrial Ca2+-efflux pathways. (1983) (20)
- Collagen VI myopathies: from the animal model to the clinical trial. (2009) (20)
- Mitochondrial oscillation and activation of H+/cation exchange (1982) (19)
- Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy (2016) (19)
- ATP synthesis during exogenous NADH oxidation. A reappraisal. (1982) (18)
- Cyclosporine before PCI in Acute Myocardial Infarction. (2016) (18)
- Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors. (2005) (16)
- Critical Evaluation of the Use of Cell Cultures for Inclusion in Clinical Trials of Patients Affected by Collagen VI Myopathies (2011) (16)
- Atmospheric-pressure ionization mass-spectrometric analysis of new anionic surfactants: The alkylpolyglucoside esters (1995) (16)
- Second‐Generation Inhibitors of the Mitochondrial Permeability Transition Pore with Improved Plasma Stability (2019) (15)
- Measurement of membrane permeability and the mitochondrial permeability transition. (2020) (14)
- Leigh Syndrome in Drosophila melanogaster (2014) (14)
- Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia (2020) (14)
- Reprint of "The mitochondrial permeability transition pore and its adaptive responses in tumor cells". (2015) (14)
- Small Molecules Targeting the Mitochondrial Permeability Transition (2015) (14)
- Potential role of cyclosporin A-sensitive mitochondrial channels in ischemia-reperfusion injury. (1995) (14)
- Lentiviral-mediated RNAi in vivo silencing of Col6a1, a gene with complex tissue specific expression pattern. (2009) (13)
- Channel formation by F-ATP synthase and the permeability transition pore: an update (2018) (12)
- Serenoa repens extract targets mitochondria and activates the intrinsic apoptotic pathway in human prostate cancer cells (2009) (12)
- Properties of the Permeability Transition of Pea Stem Mitochondria (2018) (11)
- Modulation of Ca2+ efflux and rebounding Ca2+ transport in rat liver mitochondria. (1984) (11)
- HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia (2020) (11)
- Functional Characterization of drim2, the Drosophila melanogaster Homolog of the Yeast Mitochondrial Deoxynucleotide Transporter* (2014) (11)
- Relevance of inflammation and matrix remodeling in abdominal aortic aneurysm (AAA) and popliteal artery aneurysm (PAA) progression. (2018) (11)
- Cyclophilin D Modulates Mitochondrial FOF1 ATP Synthase by Interacting with the Lateral Stalk of the Complex (2010) (11)
- The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide. (2011) (11)
- Actionable FGFR1 and BRAF mutations in adult circumscribed gliomas (2019) (11)
- Apoptosis and the laws of thermodynamics (2000) (9)
- Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin. (2021) (9)
- Interactions of Chloromethyltetramethylrosamine (Mitotracker Orange™) with Isolated Mitochondria and Intact Cells (1999) (9)
- The mechanism for Ca2+ release induced by N‐ethylmaleimide in rat liver mitochondria (1981) (9)
- Melanocytes from Patients Affected by Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy have Dysfunctional Mitochondria That Can be Rescued with Cyclophilin Inhibitors (2014) (9)
- The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation (2022) (8)
- Yeast Saccharomyces cerevisiae encodes two LETM (7)
- Assessing the molecular basis for rat-selective induction of the mitochondrial permeability transition by norbormide. (2007) (7)
- Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors. (2005) (7)
- Melanocytes — A novel tool to study mitochondrial dysfunction in Duchenne muscular dystrophy (2012) (7)
- Shc-generated Oxidative Signal Promotes Fat Accumulation * (2008) (6)
- A simple in vitro test to monitor trace metal toxicity in aqueous samples (1992) (5)
- EBEC 2012—An energetic time in Freiburg (2013) (5)
- Measurement of mitochondrial respiratory chain enzymatic activities in Drosophila melanogaster samples (2022) (5)
- Commentary: The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria (2016) (4)
- Fondation Leducq Transatlantic Network of Excellence Targeting Mitochondria to Treat Heart Disease. (2019) (4)
- Mitochondrial Volume Homeostasis: Regulation of Cation Transport Systems (1992) (4)
- Mitochondrial H+ permeability through the ADP/ATP carrier (2019) (4)
- A Novel Muscle Protein Located inside the Terminal Cisternae of the Sarcoplasmic Reticulum* (1997) (4)
- The permeability transition pore. History and perspectives of a cyclosporin A-sensitive mitochondrial channel (1995) (4)
- On the pathogenesis of collagen VI muscular dystrophies--comment on article of Hicks et al. (2009) (4)
- delta pH induced calcium fluxes in rat liver mitochondria. (1979) (3)
- Ablation of collagen VI leads to the release of platelets with altered function (2021) (3)
- Synthesis and Biological Evaluation of New Phenidone Analogues as Potential Dual Cyclooxygenase (COX‐1 and COX‐2) and Human Lipoxygenase (5‐LOX) Inhibitors. (2005) (3)
- A General and Convenient Procedure for the Synthesis of N-Alkylarylamines and N-Alkylheteroarylamines by Electrophilic Amination of Cuprates with N-Alkylhydroxylamines. (1999) (3)
- Erratum: Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, (7558-7563) DOI: 10.1073/pnas.0702228104) (2007) (3)
- From ATP to PTP and Back (2015) (2)
- 15P.24A Ca2+-regulated mitochondrial (permeability transition) pore in Drosophila melanogaster (2010) (2)
- Low P66shc with High SerpinB3 Levels Favors Necroptosis and Better Survival in Hepatocellular Carcinoma (2021) (2)
- Editorial: Structure and Function of F- and V-ATPases (2019) (2)
- The Ca 2+ regulatory site of the permeability transition pore is within the catalytic core of F-ATP synthase (2016) (2)
- Response to J. J. Lemasters et al. (1999) (2)
- EM.P.5.03 The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1 - / - myopathic mice (2009) (2)
- Displacement of Hexokinase 2 from mitochondria induces mitochondrial Ca2+ overload and calpain-dependent cell death in cancer cells (2018) (1)
- Perspectives on the Permeability Transition Pore, a Mitochondrial Channel Involved in Cell Death (1999) (1)
- Pathophysiology of the mitochondrial permeability transition (2010) (1)
- Chemical modification of the mitochondrial permeability transition pore by specific amino acid reagents (1999) (1)
- The Effects of Idebenone on Mitochondrial and Cellular Bioenergetics (2011) (1)
- Pore formation by yeast mitochondrial ATP synthase involves subunits e, g and b (2018) (1)
- Mitochondrial Permeability Transition Synthase and the Role of Dimerization in Channel Formation by Yeast F-ATP Reports : (2014) (1)
- Looking Back to the Future of Mitochondrial Research (2021) (1)
- The unique histidine of F-ATP synthase subunit OSCP mediates regulation of the permeability transition by matrix pH (2016) (1)
- Negative contrast imaging of mitochondria by confocal microscopy - Response to J.J. Lemasters et al. (Letter) (1999) (1)
- Correlative Electron Tomography and Elemental Microanalysis in Biology (2003) (1)
- Erratum (2006) (1)
- Shedding light on the permeability transition through S. cerevisiae F-ATP synthase mutagenesis (2016) (1)
- Control of ROS production and T-cell turnover by HTLV-p13 (2011) (1)
- Lethal and Nonlethal Functions of the Permeability Transition Pore (2016) (1)
- The mitochondrial permeability transition pore in Ca2+ homeostasis. (2023) (1)
- MITCHELL MEDAL LECTURE (2006) (1)
- Perspectives in mitochondrial research. Foreword (2001) (0)
- TRAP1 and cyclophilin D compete at OSCP subunit to regulate enzymatic activity and permeability transition pore opening by F-ATP synthase (2021) (0)
- Functional analysis of p13II, a mitochondrial protein coded by human T-cell leukemia virus type I (HTLV-I) (2001) (0)
- Arachidonic acid induces the mitochondrial permeability transition, cytochrome c release and apoptosis (2000) (0)
- Role of cyclophilin D in hypoxia-ischemia induced brain injury during development (2007) (0)
- P2.3 Monoamine oxidase inhibitors reduce mitochondrial ROS accumulation and dysfunction in patients with collagen VI myopathies (2011) (0)
- A further characterization of a novel variant of ATP5MC3 associated with dystonia and spastic paraplegia. (2022) (0)
- THE ROLE OF HISTOLOGY IN THE STUDY OF TUMOR CELL METABOLISM: THE TRAP1 PARADIGM (2018) (0)
- The mitochondrion : from health to disease Paolo Bernardi (2009) (0)
- A mitochondrial therapy for Duchenne muscular dystrophy (2018) (0)
- Characterization of the permeability transition pore in mitoplasts exposed to photooxidative stress (2010) (0)
- 1036 SERPINB3 INCREASES RESISTANCE TO CHEMOTHERAPEUTIC AGENTS INHIBITING ROS PRODUCTION AND THE PERMEABILITY TRANSITION PORE (2013) (0)
- The Permeability Transition Pore as Source and Target of Oxidative Stress (2003) (0)
- Arachidonic Acid Mediates Calcium-dependent Apoptosis through the Mitochondrial Pathway (2004) (0)
- Mitochondrial function and idebenone: A good therapy for Leber's hereditary optic neuropathy? (2010) (0)
- 671 SERPINB3 INCREASES RESISTANCE TO CISPLATIN- OR DOXORUBICIN-INDUCED CELL DEATH IN HEPATOMA CELLS THROUGH DEREGULATION OF PERMEABILITY TRANSITION PORE (2011) (0)
- Document S1. Supplemental Experimental Procedures and Figures S1 and S2 (2013) (0)
- Novel PTP inhibitors with potent cardioprotective efficacy (2020) (0)
- EM.I.2 Toward a mitochondrial therapy of collagen VI muscular dystrophies (2009) (0)
- S12.28 Rescue of myopathic collagen VI null mice by genetic inactivation of mitochondrial cyclophilin d (2008) (0)
- Regulation of the Mitochondrial Permeability Transition Pore by Arginine Residues of F-ATP Synthase (2018) (0)
- Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo (2018) (0)
- S10.8 Remodelling of mitochondrial function by the p13 protein of HTLV-1: Effects on reactive oxygen species and cell death (2008) (0)
- Modulation of the Mitochondrial Megachannel (2001) (0)
- G.P.15 Whole transcriptome expression profiling in COL6a1 null mice shows deregulation of circadian clock genes as exploratory COL6 myopathies biomarkers (2012) (0)
- Generation of reactive oxygen species by photoactivated calcein. Implication for mitochondrial studies (2000) (0)
- P/23 Toward a mitochondrial therapy of collagen VI muscular dystrophies (2008) (0)
- Protective effect of NIM811 – a cyclophilin inhibitor without immunosuppressive activity – in models of collagen VI muscular dystrophy (2014) (0)
- Two classes of thiol groups modulate voltage sensing by the mitochondrial transition pore. (1995) (0)
- Modulation of F-ATP synthase by pH: Role of His112 protonation of OSCP (2014) (0)
- ATP synthase in neuronal development, neurodegeneration and plasticity (2018) (0)
- Toxicity measurements in water using the response of the mitochondrial respiratory chain (1990) (0)
- The inhibitor protein IF1 modulates the permeability transition pore in a human tumorigenic cell model (2018) (0)
- Unraveling the mechanism of channel formation by F-ATP synthase (2022) (0)
- Membrane Transport | The Mitochondrial Permeability Transition Pore (2021) (0)
- Panel of wood or similar, and relative production method and machine (2005) (0)
- Protein of 18 kDa (TSPO)) Benzodiazepine Receptor (Translocator Membrane Does Not Involve the Peripheral Permeability Transition Pore by the Outer Regulation of the Mitochondrial Bioenergetics (2014) (0)
- S10.21 Quinones inhibit the mitochondrial permeability transition pore at two sites (2008) (0)
- Effect of anions on Cyclophilin D binding to F-ATP synthase: Implications for the permeability transition pore (2018) (0)
- Purpose cleaner compositions. (1989) (0)
- The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function (2018) (0)
- F-ATP synthase dimers from pea stem mitochondria are involved in PTP formation (2015) (0)
- p66shc and oxidative stress induced by post-ischemic reperfusion injury (2008) (0)
- Role of Escherichia coli hydrogenases in the F0F1-ATPase activity under mixed carbon fermentation at different pHs (2014) (0)
- 856 HEPATIC PROGENITOR CELLS OVEREXPRESS SERPINB3 IN A MOUSE MODEL OF FULMINANT HEPATITIS (2009) (0)
- Lipid utilization in skeletal muscle cells is modulated in vitro and in vivo by specific miRNAs (2018) (0)
- Functional analyses of the p13II protein of human T cell leucemia virus type I (2001) (0)
- p66 Shc -generatedOxidativeSignalPromotesFatAccumulation * □ (2008) (0)
- Assessing the relative role of F-ATP synthase and adenine nucleotide translocator in the permeability transition (2022) (0)
- Sixty-five years of the mitochondrial permeability transition: Past, present and future (2018) (0)
- EM.P.5.01 Gene expression and proteome profiles in Col6a1−/− mice, a model of Ullrich congenital muscular dystrophy (UCMD) (2009) (0)
- G.P.1.04 Design of a novel array-CGH to explore allelic and genetic heterogeneity in COLVI related myopathies (2008) (0)
- The breath of a fruit-fly (2012) (0)
- Cytoskeletal mitochondrial interactions in collagen VI related disorders (2016) (0)
- Collagen VI myopathies: pathogenic mechanism and therapeutic strategies (2011) (0)
- The idebenone metabolite QS10 is an electron donor to complex III and rescues respiration in complex I-deficient cells and rotenone-treated zebrafish (2016) (0)
- The mitochondrial permeability transition, F-ATP synthase and the adenine nucleotide translocator: Where do we stand? (2022) (0)
- Cyclophilin D interaction with the ATP synthase oligomeric forms (2010) (0)
- Do dimers of ATP synthase form the PTP in pea stem mitochondria (2016) (0)
- Pathways and regulation of Ca++ transport in rat liver mitochondria (1979) (0)
- Cyclophilin D isomerase activity controls FoF1-ATP synthase oligomerization and mitochondrial ultrastructure (2018) (0)
- P3.083 Dopamine oxidation products as mitochondrial endotoxins, a potential molecular mechanism for selective neurodegeneration in Parkinson disease (2009) (0)
- Silencing of mitochondrial Lon protease deeply alters mitochondrial proteome and functionality in RKO colorectal carcinoma cells (2014) (0)
- 19th European Bioenergetics Conference-Preface. (2016) (0)
- Inner Membrane Permeabilization – The Permeability Transition (2014) (0)
- M.P.1.01 Pilot trial with cyclosporin A in patients with collagen VI myopathies (2009) (0)
- VDAC1 and the mitochondrial permeability transition (2004) (0)
- Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases (2017) (0)
- Role of F-ATP synthase f subunit in dimer formation and PTP modulation (2018) (0)
- Potential role of cyclosporin A-sensitive channels in ischemia-reperfusion injury. (1995) (0)
- Investigating the roles of F-ATP synthase dimerization subunits e and g in Drosophila melanogaster (2022) (0)
- Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement (2022) (0)
- Figure 4.1.1, Structures for Compounds Reported to inhibit the mtPTP (2015) (0)
- Bioenergetic characterization of a neurofibromatosis type-1 cell model (2012) (0)
- Polyglukosiden from Hydroxyalkylsorbit. (1992) (0)
- The Outer Membrane-Translocator Protein Mediates Activation of the Mitochondrial Permeability Transition by Porphyrin-Based Photooxidative Stress (2011) (0)
- The Permeability Transition Pore. Pathophysiology of a Cyclosporin A-sensitive Mitochondrial Channel (1994) (0)
- Cyclophilin D knockout mice do not accumulate succinate during cardiac ischemia. (2022) (0)
- PO-032 Displacement of hexokinase 2 from mitochondria induces mitochondrial Ca2 +overload and caspase-independent cell death in cancer cells (2018) (0)
- Toward a mitochondrial therapy of collagen VI muscular dystrophies (TELETHON GRANT GGPO8107) (2007) (0)
- Functional analyses of P13II, a mitochondrial protein of human T-cell leukemia virus type-1 (2004) (0)
- Protective effect of Alisporivir – a cyclophilin inhibitor without immunosuppressive activity – in Duchenne muscular dystrophy (2016) (0)
- The protease inhibitor SERPINB3 inhibits permeability transition pore through the regulation of mitochondrial Complex I ROS production (2012) (0)
- Abstract not received (2018) (0)
- Histones destabilize the mitochondrial membrane organization and cause release of cytochrome c (2012) (0)
- The Dual Life of Mitochondrial F-ATP Synthase (2020) (0)
- Regulation of the mitochondrial permeability transition pore by membrane potential through modulation of voltage sensing. (1993) (0)
- Mitochondrial ion channels as targets for cardioprotection Mitochondrial ion channels as targets for cardioprotection. (0)
- Electrophysiological properties of channel formed by bovine FOF1 ATP synthase in planar lipid bilayer (2018) (0)
- Characterization of the mitochondrial function and genetics in the pathogenesis of collagen VI related disorders (958.1) (2014) (0)
- Bernardi Mitochondria in muscle cell death * (0)
- F-55 SERPINB3 increases resistance to chemotherapeutic agents inhibiting ROS production and the permeability transition pore (2013) (0)
- S12.30 Apoptosis regulation by the mitochondrial chaperone trap-1/hsp-75 (2008) (0)
- O.17 Autophagy thwarts collagen VI muscular dystrophies (2011) (0)
- Phenyl-substituted maleimide as medicaments for the inhibition of degenerative tissue damage by inhibiting mpt (2007) (0)
- Tridimensional ex vivo culture of prostate tissue blocks: An ulstrastructural study (2003) (0)
- Species specific stimulation of the mitochondrial permeability transition by norbormide and its derivatives (2006) (0)
- Mitochondrial Permeability Transition (2022) (0)
- P4.50 Mitochondrial therapy with Cyclosporine A in patients with Ullrich Congenital Muscular Dystrophy (2011) (0)
- S3.23 Cyclophilin D sensitizes the mitochondrial permeability transition to phosphate (2008) (0)
- Foreword (0)
- Introduction to the special issue "Cold Spring Harbor Asia Conference on Mitochondria". (2018) (0)
- TRAP1 regulation in cancer metabolism: identification of new interactors (2018) (0)
- Multipurpose washing composition (1989) (0)
- Ca2 +-induced Ca2 + release in Drosophila mitochondria is mediated by dimers of F-ATP synthase (2014) (0)
- The N-terminus of Cyclophilin D modulates its binding to ATP synthase (2022) (0)
- Characterization of CyPD - FOF1ATP synthase interaction: Role of the OSCP subunit (2012) (0)
- EM.P.5.02 Role of mitochondria in the pathogenesis of muscular dystrophies (2009) (0)
- 280: Silencing of mitochondrial Lon protease deeply alters mitochondrial proteome and functionality in RKO colorectal carcinoma cells (2014) (0)
- The mitochondrial mechanisms of cell killing by the Bcl-2 ligand HA14-1 (2002) (0)
- Discovery and characterization of small molecular inhibitors of the mitochondrial permeability transition pore (2016) (0)
- Time‐resolved storage and retrieval of Ca2+ signals by mitochondria depends on matrix Ca2+ hotspots (1999) (0)
- FOF1-ATP Synthase Dimers and The Mitochondrial Permeability Transition Pore from Yeast to Mammals (2014) (0)
- 771 The opening of the permeability transition pore is responsible for mitochondrial dysfunction and cell death caused by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (2003) (0)
- Cleaning compositions of a general nature. (1989) (0)
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