Nicholas Navin
#109,670
Most Influential Person Now
American biologist
Nicholas Navin's AcademicInfluence.com Rankings
Nicholas Navinbiology Degrees
Biology
#5997
World Rank
#8610
Historical Rank
#1982
USA Rank
Genetics
#1057
World Rank
#1156
Historical Rank
#268
USA Rank
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Biology
Nicholas Navin's Degrees
- PhD Genetics University of Texas at Austin
- Bachelors Biochemistry University of Texas at Austin
Why Is Nicholas Navin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nicholas Navin is an American biologist, and the Grady Saunders Distinguished Professor at the University of Texas MD Anderson Cancer Center. Nicholas Navin has pioneered the development of the first single cell sequencing methods for DNA
Nicholas Navin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Large-Scale Copy Number Polymorphism in the Human Genome (2004) (2571)
- Tumour evolution inferred by single-cell sequencing (2011) (2330)
- Clonal Evolution in Breast Cancer Revealed by Single Nucleus Genome Sequencing (2014) (902)
- Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing (2018) (596)
- Toward understanding and exploiting tumor heterogeneity (2015) (557)
- Inferring tumor progression from genomic heterogeneity. (2010) (503)
- WW Domain-containing Protein YAP Associates with ErbB-4 and Acts as a Co-transcriptional Activator for the Carboxyl-terminal Fragment of ErbB-4 That Translocates to the Nucleus* (2003) (476)
- Advances and applications of single-cell sequencing technologies. (2015) (449)
- Punctuated Copy Number Evolution and Clonal Stasis in Triple-Negative Breast Cancer (2016) (375)
- Genome-wide copy number analysis of single cells (2012) (332)
- Novel patterns of genome rearrangement and their association with survival in breast cancer. (2006) (322)
- The first five years of single-cell cancer genomics and beyond (2015) (299)
- Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing (2018) (273)
- Cancer genomics: one cell at a time (2014) (253)
- Insight into the heterogeneity of breast cancer through next-generation sequencing. (2011) (235)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- Tumor evolution: Linear, branching, neutral or punctuated? (2017) (220)
- Future medical applications of single-cell sequencing in cancer (2011) (194)
- Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer (2017) (165)
- Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. (2011) (156)
- Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics (2020) (156)
- Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes (2021) (145)
- Tracing the tumor lineage (2010) (131)
- Monovar: single nucleotide variant detection in single cells (2016) (127)
- Advancing Cancer Research and Medicine with Single-Cell Genomics. (2020) (126)
- SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models (2017) (118)
- Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). (2009) (113)
- Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer (2017) (93)
- SNES: single nucleus exome sequencing (2015) (86)
- Breast Tumors Maintain a Reservoir of Subclonal Diversity During Expansion (2021) (86)
- Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial. (2019) (81)
- Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells (2020) (77)
- SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data (2018) (75)
- Genome evolution in ductal carcinoma in situ: invasion of the clones (2017) (70)
- Single-cell analysis at the threshold (2016) (60)
- Identification of alterations in DNA copy number in host stromal cells during tumor progression (2006) (55)
- Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response (2020) (53)
- Highly multiplexed targeted DNA sequencing from single nuclei (2016) (46)
- Tumor evolution in response to chemotherapy: phenotype versus genotype. (2014) (44)
- Computing tumor trees from single cells (2016) (43)
- Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability as a Distinctive Feature of Aggressive Prostate Cancer (2020) (42)
- Methods for copy number aberration detection from single-cell DNA-sequencing data (2019) (40)
- Delineating cancer evolution with single-cell sequencing (2015) (39)
- Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq (2016) (37)
- SCOPIT: sample size calculations for single-cell sequencing experiments (2019) (34)
- Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases (2018) (30)
- PROBER: oligonucleotide FISH probe design software (2006) (30)
- Spatial charting of single-cell transcriptomes in tissues (2021) (30)
- Methods for copy number aberration detection from single-cell DNA-sequencing data (2020) (28)
- Computational approaches for inferring tumor evolution from single-cell genomic data (2018) (28)
- Distribution of short paired duplications in mammalian genomes. (2004) (27)
- Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis (2017) (27)
- BreakTrans: uncovering the genomic architecture of gene fusions (2013) (26)
- MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
- SCMarker: Ab initio marker selection for single cell transcriptome profiling (2018) (20)
- Assessing the performance of methods for copy number aberration detection from single-cell DNA sequencing data (2020) (19)
- Transient commensal clonal interactions can drive tumor metastasis (2020) (17)
- Genotyping tumor clones from single-cell data (2016) (17)
- Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer (2022) (16)
- The aggressive variant prostate carcinoma (AVPC) molecular signature (-MS) and platinum-sensitivity in castration resistant prostate cancer (CRPC). (2017) (15)
- Correction: Corrigendum: Genome-wide copy number analysis of single cells (2016) (15)
- High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors. (2005) (15)
- Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma (2020) (13)
- Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility. (2021) (11)
- MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution (2021) (11)
- Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis (2022) (11)
- MEDALT: single-cell copy number lineage tracing enabling gene discovery (2021) (9)
- Toward an Integrated Knowledge Environment to Support Modern Oncology (2011) (9)
- Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing (2020) (7)
- Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations (2015) (6)
- SiFit: A Method for Inferring Tumor Trees from Single-Cell Sequencing Data under Finite-site Models (2016) (6)
- MEDALT: single-cell copy number lineage tracing enabling gene discovery (2020) (6)
- Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma in situ (2021) (6)
- Learning to distinguish progressive and non-progressive ductal carcinoma in situ (2022) (5)
- Learning to distinguish progressive and non-progressive ductal carcinoma in situ (2022) (5)
- Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing (2021) (5)
- Single cell sequencing reveals trajectory of tumor-infiltrating lymphocyte states in pancreatic cancer. (2022) (4)
- Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer (2022) (4)
- Probing WW Domains to Uncover and Refine Determinants of Specificity in Ligand Recognition (2003) (4)
- Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics (2020) (3)
- for single-cell sequencing data (2020) (3)
- A Decade's Experience in Pediatric Chromosomal Microarray Reveals Distinct Characteristics Across Ordering Specialties. (2022) (2)
- IMMU-35. TRANSCRIPTIONALLY DEFINED IMMUNE CONTEXTURE IN HUMAN GLIOMAS AT SINGLE-CELL RESOLUTION (2020) (2)
- New frontiers in single-cell genomics (2021) (2)
- Abstract 157: Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer (2016) (2)
- Aggressive variant prostate cancer (AVPC) molecular signature in castration-sensitive, de novo metastatic prostate cancer (M1PCa). (2019) (2)
- Highly correlated feature set selection for data clustering (2014) (2)
- Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients (2022) (2)
- Resident Breast T Cells: The Troops Are Already There. (2018) (1)
- BreakTrans: uncovering the genomic architecture of gene fusions (2013) (1)
- Resolving clonal substructure from single cell genomic data using CopyKit (2022) (1)
- Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. (2023) (1)
- Comments on the model parameters in “SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models” (2019) (1)
- Targeting Polo-like Kinase 4 Triggers Polyploidy and Apoptotic Cell Death in TP53-Mutant Acute Myeloid Leukemia (2021) (1)
- Abstract 446: Plasma genome sequencing identifies prostate cancer patients that are sensitive to platinum-based therapy (2019) (1)
- Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing (2020) (1)
- Author Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics (2021) (1)
- Antibody-independent isolation and characterization of circulating tumor cells using dielectrophoresis: Fluid flow fractionation in metastatic colorectal cancer. (2016) (1)
- Abstract 2192: Single-molecule single-cell DNA sequencing identifies ongoing copy number evolution in BRCA breast cancers (2018) (1)
- Abstract 5399: Investigating phenotypic plasticity in breast cancer with high-throughput nanogrid single-nucleus RNA sequencing (2017) (1)
- Minimal Event Distance Aneuploidy Lineage Tree (MEDALT) inference based on single cell copy number profile v1 (2020) (1)
- BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status (2013) (1)
- Abstract ES5-3: Investigating Breast Cancer with Single-Cell Sequencing (2012) (1)
- Abstract PD10-08: Remodeling the inflammatory breast cancer tumor microenvironment to enhance immunotherapy: Novel therapeutic development (2022) (1)
- Abstract 2084: Single-cell multimodal glioma analyses reveal epigenetic regulators of cellular plasticity and environmental stress response (2021) (1)
- Cancer genomics: one cell at a time (2014) (1)
- Abstract 3665: Longitudinal monitoring of prostate cancer evolution by plasma genome sequencing (2018) (1)
- Abstract PO-133: Breast tumors maintain a reservoir of subclonal diversity during primary expansion (2020) (0)
- Abstract PS11-41: A spatially resolved single cell atlas of the human breast (2020) (0)
- Abstract 3308: Chemoradiation sensitization effect of PARPi in non-small cell lung cancer (2022) (0)
- Abstract IA013: A single-cell and spatial investigation of tumor and TME for DCIS (2022) (0)
- Abstract 2147: Decoding the natural biology of triple-negative breast cancer and response to chemotherapy by single-cell transcriptomics (2023) (0)
- Abstract 5782: The dynamic immune behavior of primary and metastatic tumors of ovarian cancer (2023) (0)
- 727 – Wnt11 Promotes Pancreatic Cancer Cell Motility and Invasion (2019) (0)
- Abstract P1-22-05: Identifying predictors of invasive recurrence based on molecular profiles of DCIS lesions (2022) (0)
- Abstract 2375: Multiclonal invasion in breast cancer identified by single cell DNA sequencing (2016) (0)
- Abstract 669: Immunophenotyping of human brain tumors reveals myeloid cell mediated anti-glioma axis (2023) (0)
- Abstract 418: Adaptive resistance to chemotherapy in triple-negative breast cancer revealed by single cell DNA and RNA sequencing (2017) (0)
- Abstract 2893: Sleeping Beauty uncovers cooperating driver genes in a preclinical mouse model of myeloid leukemia (2015) (0)
- Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations (2015) (0)
- Transcriptional Inactivation of TP53 and the BMP Pathway Mediates Therapy-induced Dedifferentiation and Metastasis in Prostate Cancer (2021) (0)
- Abstract 5599: Noninvasive genomic profiling of cerebral spinal fluid in breast cancer patient with leptomeningeal disease (2018) (0)
- 833 The epigenomic landscape of human glioma-associated myeloid cells (2020) (0)
- Alterations in chromosome organization and structure (2006) (0)
- Immune landscape of isocitrate dehydrogenase stratified human 1 gliomas 2 (2022) (0)
- Abstract LB-310: Single cell genome sequencing reveals clonal stability and diversity in breast cancer (2014) (0)
- OmicPioneer-sc: an integrated, interactive visualization environment for single-cell sequencing data (2020) (0)
- High-resolution representational oligonucleotide microarray analysis and fluorescence in situ hybridization analysis of aneuploid and diploid breast tumors (2005) (0)
- High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL. (2008) (0)
- Abstract P4-06-03: Assessment of intratumoral heterogeneity in early stage estrogen receptor (ER) positive breast cancer (2020) (0)
- Characterization of Dysregulated Transcription in TP53-Mutated AML Subpopulations (2022) (0)
- Corrigendum to “Tracing the tumor lineage” [Mol. Oncol. 4 (2010) 267–283] (2011) (0)
- Abstract 4424: Medatree enabling single cell copy number lineage tracing and functional discovery (2020) (0)
- SCOPIT: sample size calculations for single-cell sequencing experiments (2019) (0)
- varietal count nucleic acids for information on the number of genomic copies (2011) (0)
- Somatic Mutations in TP53 Identified in T-Cells of Patients with TP53-mutated AML (2022) (0)
- Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ (2022) (0)
- Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ (2022) (0)
- GENOMIC ANALYSIS OF CANCER AND HUMAN GENETIC DISORDERS (2013) (0)
- Identification of Gene Expression Signatures in Leukemia Stem Cells and Minimal Residual Disease Following Treatment of Adverse Risk Acute Myeloid Leukemia (2019) (0)
- OTME-23. Single-cell transcriptomic and epigenomic immune landscape of isocitrate dehydrogenase stratified human gliomas (2021) (0)
- Single Cell Sequencing of Pancreatic Ductal Adenocarcinoma Reveals a Paradoxical Immunosuppressive Microenvironment Following Stereotactic Body Radiation Therapy (2022) (0)
- CTNI-02. TBCRC049: A PHASE II STUDY TO ASSESS THE SAFETY AND EFFICACY OF THE COMBINATION OF TUCATINIB, TRASTUZUMAB AND CAPECITABINE FOR THE TREATMENT OF LEPTOMENINGEAL METASTASIS IN HER2 POSITIVE BR1AST CANCER (2020) (0)
- Abstract 3791: Investigating longitudinal therapeutic resistance in serially treated metastatic castration resistant prostate cancer by liquid biopsy genome sequencing (2022) (0)
- Abstract 2371: Multi-cell phylogenetic inference of copy number evolution in breast cancer (2016) (0)
- Abstract 5702: A spatially resolved single cell atlas of the human breast (2020) (0)
- Abstract 515: Single-cell transcriptomic analysis of HR+/HER2- breast cancer identifies gene signatures that predict outcomes of luminal A and B subtypes (2022) (0)
- SNES: single nucleus exome sequencing (2015) (0)
- Abstract PL1: Breast Tumor Evolution and Intratumor Heterogeneity - Insights from Single Cell Genomics (2019) (0)
- EPCO-27. GLIOMA SINGLE CELL MULTI-OMIC ANALYSES REVEALS REGULATORS OF PLASTICITY AND ADAPTIVE STRESS RESPONSE (2020) (0)
- Deconvolution of Clonal Heterogeneity in Acute Myeloid Leukemia using Single-Cell DNA Sequencing (2019) (0)
- Abstract IA025: Decoding breast cancer evolution with single cell genomics (2022) (0)
- Abstract 93: Single cell transcriptome analysis maps dynamic epithelial mesenchymal transition and immunological remodeling in thyroid cancer progression (2021) (0)
- Abstract 2501: Delineating mutational lineages with single cell DNA sequencing using multi-patient specific panels (2020) (0)
- SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models (2017) (0)
- Tracing Tumor Lineage and Progression through Genomic Copy Number Profiling at the Single Cell Level (2010) (0)
- COPY-NUMBER ANALYSIS AND HUMAN DISEASE (2013) (0)
- IMMU-43. IMMUNE CONTEXTURE OF ISOCITRATE DEHYDROGENASE STRATIFIED HUMAN GLIOMAS REVEALED BY SINGLE-CELL TRANSCRIPTOMICS AND ACCESSIBLE CHROMATIN (2021) (0)
- Abstract 2477: CopyCat: estimating genomic copy number profiles from high-throughput single cell RNA seq data (2019) (0)
- Abstract P5-01-17: Unbiased copy number analysis of circulating tumor DNA among HER2-positive breast cancer patients (2020) (0)
- Abstract PO-017: Single-cell copy number heterogeneity tracing enabling cancer gene discovery (2020) (0)
- Computing tumor trees from single cells (2016) (0)
- Comments on the model parameters in “SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models” (2019) (0)
- Abstract IA22: Investigating breast cancer evolution and diversity with single-cell sequencing (2015) (0)
- Abstract GS1-02: Towards a human breast cell atlas (2019) (0)
- Abstract PO-020: Inferring copy number substructure from single-cell transcriptomics in human tumors with CopyKat (2020) (0)
- Distinct Gene Expression Patterns of Minimal Residual Disease (MRD) Cells in High-Risk AML Patients Identified By RNA-Sequencing (2018) (0)
- 1001 Immunophenotyping of brain tumors identifies interferon enriched phagocytes in human gliomas (2022) (0)
- Abstract IA14: Breast cancer evolution – Insights from single cell genomics (2020) (0)
- Abstract 5054: Inferring mutational chronology in breast cancer by deep-sequencing tumor subpopulations (2012) (0)
- Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases (2018) (0)
- Abstract 2847: Simultaneous TCR and transcriptomic sequencing of single Tcells defines biological subtypes in pancreatic cancer for adoptive Tcell therapy (2022) (0)
- Abstract 3131: Anaplastic transformation model in thyroid cancer revealed by single cell lineage and fate analysis (2023) (0)
- Abstract 1210: Resolving clonal substructure from single cell genomic data in primary and metastatic tumors using CopyKit (2022) (0)
- Abstract 3776: Spatially resolved immunogenomic analyses reveal diverse sub tumoral microenvironments in the context of melanoma immunotherapy (2019) (0)
- Abstract 76: Reprogramming of the preinvasive breast microenvironment identified by spatial nucleus barcoding (2023) (0)
- Abstract LB-170: Single cell sequencing identifies clonal stasis and punctuated copy number evolution in triple-negative breast cancer patients (2015) (0)
- Abstract 2738: Wnt11 regulates migration and invasion in pancreatic ductal adenocarcinoma (2019) (0)
- Characterizing Intratumoral Heterogeneity : A Role for Cell Plasticity (2016) (0)
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What Schools Are Affiliated With Nicholas Navin?
Nicholas Navin is affiliated with the following schools:
