David M. Knipe | Academic Influence

David M. Knipe's AcademicInfluence.com Rankings

David M. Knipe

Biology

#3543

World Rank

#5404

Historical Rank

#1429

USA Rank

Virology

#87

World Rank

#90

Historical Rank

#30

USA Rank

Microbiology

#273

World Rank

#317

Historical Rank

#93

USA Rank

biology Degrees

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Biology

David M. Knipe's Degrees

PhD Microbiology University of California, Berkeley
Bachelors Biology University of California, Berkeley

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Why Is David M. Knipe Influential?

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According to Wikipedia, David Mahan Knipe is the Higgins Professor of Microbiology and Molecular Genetics in the Department of Microbiology at the Harvard Medical School in Boston, Massachusetts and co-chief editor of the reference book Fields Virology. He returned to the Chair of the Program in Virology at Harvard Medical School in 2019, having previously held the position from 2004 through 2016 and served as interim Co-Chair of the Microbiology and Immunobiology Department from 2016 through 2018.

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David M. Knipe's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. (2004) (632)
Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2 (2003) (432)
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection (2006) (417)
Chromatin control of herpes simplex virus lytic and latent infection (2008) (391)
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein (2012) (390)
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency (1989) (388)
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. (1989) (368)
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency (1989) (359)
The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication (1984) (333)
Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells (1979) (310)
Functions of Cytoplasmic Fibers in Non-Muscle Cell Motility (1973) (306)
Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein (1988) (287)
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27 (1990) (277)
Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides (1981) (262)
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. (2005) (259)
Proteomics of Herpes Simplex Virus Replication Compartments: Association of Cellular DNA Replication, Repair, Recombination, and Chromatin Remodeling Proteinswith ICP8 (2004) (250)
Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. (1985) (249)
Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells. (1988) (244)
Herpes Simplex Virus 1 Has Multiple Mechanisms for Blocking Virus-Induced Interferon Production (2004) (219)
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection (2015) (202)
Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters (2009) (198)
A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1 (1997) (193)
Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress (2009) (192)
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4 (1987) (185)
Herpes Simplex Virus ICP0 Promotes both Histone Removal and Acetylation on Viral DNA during Lytic Infection (2008) (184)
Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation. (1986) (183)
A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction (2014) (183)
Separate pathways of maturation of the major structural proteins of vesicular stomatitis virus (1977) (175)
Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27 (1988) (171)
Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. (2007) (169)
Replication-defective viruses as vaccines and vaccine vectors. (2006) (168)
HSV‐1 ICP27 targets the TBK1‐activated STING signalsome to inhibit virus‐induced type I IFN expression (2016) (159)
Numerous Conserved and Divergent MicroRNAs Expressed by Herpes Simplex Viruses 1 and 2 (2010) (154)
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA (2013) (150)
Identification and Functional Evaluation of Cellular and Viral Factors Involved in the Alteration of Nuclear Architecture during Herpes Simplex Virus 1 Infection (2005) (148)
Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus (1982) (144)
Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus (1977) (144)
Humoral response to herpes simplex virus is complement-dependent. (1999) (143)
Herpes Simplex Virus 1 UL31 and UL34 Gene Products Promote the Late Maturation of Viral Replication Compartments to the Nuclear Periphery (2004) (141)
Snapshots: chromatin control of viral infection. (2013) (140)
Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures (1996) (135)
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. (2008) (134)
Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells (2003) (129)
Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes (1996) (128)
Vaccine Protection against Simian Immunodeficiency Virus by Recombinant Strains of Herpes Simplex Virus (2000) (122)
Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein (1989) (122)
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons (1993) (122)
Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection (1994) (118)
Palmitoylation of the cysteine-rich endodomain of the SARS–coronavirus spike glycoprotein is important for spike-mediated cell fusion (2006) (117)
Role of Specific Innate Immune Responses in Herpes Simplex Virus Infection of the Central Nervous System (2011) (115)
Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression (1991) (113)
Comparative Efficacy and Immunogenicity of Replication-Defective, Recombinant Glycoprotein, and DNA Vaccines for Herpes Simplex Virus 2 Infections in Mice and Guinea Pigs (2005) (111)
Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge. (1998) (111)
Herpes Simplex Virus Immediate-Early ICP0 Protein Inhibits Toll-Like Receptor 2-Dependent Inflammatory Responses and NF-κB Signaling (2010) (110)
Association of Herpes Simplex Virus Type 1 ICP8 and ICP27 Proteins with Cellular RNA Polymerase II Holoenzyme (2002) (109)
The role of toll-like receptors in herpes simplex infection in neonates. (2005) (106)
Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses* (2014) (102)
Viral replication is required for induction of ocular immunopathology by herpes simplex virus (1996) (101)
Localization of two cellular forms of the vesicular stomatitis viral glycoprotein (1977) (101)
Herpesvirus tegument protein activates NF-κB signaling through the TRAF6 adaptor protein (2008) (101)
Construction, Phenotypic Analysis, and Immunogenicity of a UL5/UL29 Double Deletion Mutant of Herpes Simplex Virus 2 (2000) (101)
Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation. (1989) (99)
Molecular genetics of herpes simplex virus: demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion. (1978) (99)
Cellular sensing of viral DNA and viral evasion mechanisms. (2014) (95)
Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities (1989) (95)
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach (2012) (94)
Accumulation of Viral Transcripts and DNA during Establishment of Latency by Herpes Simplex Virus (1998) (92)
Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA (2011) (92)
Preexisting nuclear architecture defines the intranuclear location of herpesvirus DNA replication structures (1994) (91)
Herpes simplex virus replication compartments can form by coalescence of smaller compartments. (2003) (89)
Molecular Genetics of Herpes Simplex Virus VI. Characterization of a Temperature-Sensitive Mutant Defective in the Expression of All Early Viral Gene Products (1981) (88)
Herpes simplex virus 1 ICP27 is required for transcription of two viral late (gamma 2) genes in infected cells. (2001) (88)
Herpes Simplex Virus-Induced Keratitis: Evaluation of the Role of Molecular Mimicry in Lesion Pathogenesis (2001) (85)
Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. (2004) (85)
Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection. (1999) (83)
The acidic amino-terminal region of herpes simplex virus type 1 alpha protein ICP27 is required for an essential lytic function (1993) (83)
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities (2012) (82)
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein (1991) (81)
Replication-defective mutants of herpes simplex virus (HSV) induce cellular immunity and protect against lethal HSV infection (1992) (80)
Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease. (1997) (79)
Herpes Simplex Virus 1 Immediate-Early and Early Gene Expression during Reactivation from Latency under Conditions That Prevent Infectious Virus Production (2005) (79)
A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation. (2016) (78)
Assembly of herpes simplex virus replication proteins at two distinct intranuclear sites. (1997) (77)
Herpes simplex virus infection blocks events in the G1 phase of the cell cycle. (2000) (77)
Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions. (1998) (77)
Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection (2004) (76)
Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific viral proteins (1977) (76)
Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1. (1996) (75)
Translation of individual species of vesicular stomatitis viral mRNA (1975) (75)
Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression (1983) (75)
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses (1990) (74)
Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion (2005) (74)
Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes (2014) (73)
Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation. (2000) (73)
Neither LAT nor Open Reading Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus (2002) (72)
Herpes Simplex Virus ICP27 Increases Translation of a Subset of Viral Late mRNAs (2008) (72)
Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity. (2015) (72)
Cutting Edge: Myeloid Complement C3 Enhances the Humoral Response To Peripheral Viral Infection1 (2001) (72)
Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1. (1997) (70)
Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation. (2010) (70)
Kinetics of Facultative Heterochromatin and Polycomb Group Protein Association with the Herpes Simplex Viral Genome during Establishment of Latent Infection (2013) (69)
Role for A-Type Lamins in Herpesviral DNA Targeting and Heterochromatin Modulation (2008) (69)
Herpes simplex virus. (2002) (68)
Herpes Simplex Virus 1 Glycoprotein B and US3 Collaborate To Inhibit CD1d Antigen Presentation and NKT Cell Function (2011) (68)
HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: selective upregulation of IL-6 gene expression. (1996) (68)
Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia. (2011) (67)
Genome Sequencing and Analysis of Geographically Diverse Clinical Isolates of Herpes Simplex Virus 2 (2015) (67)
Nucleotide sequence complexities, molecular weights, and poly(A) content of the vesicular stomatitis virus mRNA species (1975) (66)
Herpes Simplex Virus Vectors Elicit Durable Immune Responses in the Presence of Preexisting Host Immunity (2002) (66)
Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. (1977) (65)
Myeloid C3 Determines Induction of Humoral Responses to Peripheral Herpes Simplex Virus Infection 1 (2003) (65)
Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes (1985) (64)
An immunoassay for the study of DNA-binding activities of herpes simplex virus protein ICP8 (1985) (64)
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors (1994) (63)
Characterization of herpes simplex virus 2 temperature-sensitive mutants whose lesions map in or near the coding sequences for the major DNA-binding protein (1983) (63)
Mechanism of virus-induced Ig subclass shifts. (1994) (63)
The role of viral and cellular nuclear proteins in herpes simplex virus replication. (1989) (63)
A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins (1986) (62)
Latent Herpes Simplex Virus Infection of Sensory Neurons Alters Neuronal Gene Expression (2003) (62)
Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia (1993) (62)
Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1 (1983) (61)
Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1 (1982) (61)
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs. (2009) (61)
Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding. (1988) (60)
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. (2007) (60)
Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection (2016) (59)
Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1 (1984) (58)
Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions. (2001) (57)
Molecular genetics of herpes simplex virus. III. Fine mapping of a genetic locus determining resistance to phosphonoacetate by two methods of marker transfer (1979) (55)
Association between the herpes simplex virus major DNA-binding protein and alkaline nuclease (1992) (55)
Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination. (2013) (54)
Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types (2016) (53)
Genetic studies on murine susceptibility to herpes simplex keratitis. (1986) (52)
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4 (1996) (52)
Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach. (2007) (51)
Distal protein sequences can affect the function of a nuclear localization signal. (1992) (51)
Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus. (1996) (51)
Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication (1996) (51)
Macrophage-Derived Complement Component C4 Can Restore Humoral Immunity in C4-Deficient Mice1 (2002) (50)
Nuclear localization of herpesvirus proteins: potential role for the cellular framework (1983) (50)
Herpes simplex virus and toll-like receptors. (2005) (50)
Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site (1991) (49)
Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease. (2017) (49)
Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model. (2000) (48)
ICP22 Is Required for Wild-Type Composition and Infectivity of Herpes Simplex Virus Type 1 Virions (2006) (45)
Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs. (2008) (45)
Herpes Simplex Virus VP16, but Not ICP0, Is Required To Reduce Histone Occupancy and Enhance Histone Acetylation on Viral Genomes in U2OS Osteosarcoma Cells (2009) (45)
Stalking the Sacrifice (1986) (44)
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection. (2001) (44)
Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication (2018) (43)
A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations (2017) (43)
Human Cytomegalovirus UL44 Concentrates at the Periphery of Replication Compartments, the Site of Viral DNA Synthesis (2011) (43)
Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector. (2007) (42)
Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa. (2011) (40)
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation (2017) (39)
Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins (2015) (39)
The Role of Herpes Simplex Virus ICP27 in the Regulation of UL24 Gene Expression by Differential Polyadenylation (1998) (38)
Immunization with a replication-deficient mutant of herpes simplex virus type 1 (HSV-1) induces a CD8+ cytotoxic T-lymphocyte response and confers a level of protection comparable to that of wild-type HSV-1 (1997) (35)
Molecular genetics of herpes simplex virus: the terminal a sequences of the L and S components are obligatorily identical and constitute a part of a structural gene mapping predominantly in the S component. (1979) (35)
On the structure, functional equivalence, and replication of the four arrangements of herpes simplex virus DNA. (1979) (34)
Discovery of a novel TLR2 signaling inhibitor with anti-viral activity. (2010) (34)
Identification of TRIM27 as a Novel Degradation Target of Herpes Simplex Virus 1 ICP0 (2014) (34)
A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription. (1996) (34)
Identification of a Divalent Metal Cation Binding Site in Herpes Simplex Virus 1 (HSV-1) ICP8 Required for HSV Replication (2012) (34)
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity (2019) (34)
ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress (2018) (34)
A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin (2016) (34)
Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection (2019) (34)
CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection (2018) (33)
A Dominant-Negative Herpesvirus Protein Inhibits Intranuclear Targeting of Viral Proteins: Effects on DNA Replication and Late Gene Expression (2000) (32)
Genetic engineering of a modified herpes simplex virus 1 vaccine vector. (2009) (32)
Optimal Long-Term Humoral Responses to Replication-Defective Herpes Simplex Virus Require CD21/CD35 Complement Receptor Expression on Stromal Cells (2006) (31)
Type 3 reovirus neuroinvasion after intramuscular inoculation: direct invasion of nerve terminals and age-dependent pathogenesis. (2002) (30)
Genetic and Molecular In Vivo Analysis of Herpes Simplex Virus Assembly in Murine Visual System Neurons (2005) (30)
ICP27 Selectively Regulates the Cytoplasmic Localization of a Subset of Viral Transcripts in Herpes Simplex Virus Type 1-Infected Cells (2004) (30)
Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling (2017) (30)
HIV Integrase Inhibitors Block Replication of Alpha-, Beta-, and Gammaherpesviruses (2014) (29)
Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses. (1993) (29)
Genomic sequences of a low passage herpes simplex virus 2 clinical isolate and its plaque-purified derivative strain. (2014) (29)
Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes. (2008) (28)
Herpes Simplex Virus Infection Blocks Events in the G 1 Phase of the Cell Cycle (2000) (28)
CD200R1 Supports HSV-1 Viral Replication and Licenses Pro-Inflammatory Signaling Functions of TLR2 (2012) (27)
Mapping of the transcriptional initiation site of the herpes simplex virus type 1 ICP8 gene in infected and transfected cells (1987) (27)
CNBP controls IL-12 gene transcription and Th1 immunity (2018) (27)
Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 (2019) (27)
Previous immunization of mice with herpes simplex virus type-1 strain MP protects against secondary corneal infection. (1986) (26)
HSV-1 remodels host telomeres to facilitate viral replication. (2014) (26)
Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease. (2007) (26)
Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate-Early Genes (2012) (25)
History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains. (2016) (25)
Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein. (2010) (25)
Simian TRIM5alpha proteins reduce replication of herpes simplex virus. (2010) (24)
Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses. (2015) (23)
A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression (2014) (23)
Intragenic complementation of herpes simplex virus ICP8 DNA-binding protein mutants (1993) (23)
Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. (2005) (23)
Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus (2015) (21)
Summary and recommendations from a National Institute of Allergy and Infectious Diseases (NIAID) workshop on "Next Generation Herpes Simplex Virus Vaccines". (2014) (20)
Cellular SNF2H Chromatin-Remodeling Factor Promotes Herpes Simplex Virus 1 Immediate-Early Gene Expression and Replication (2011) (20)
Production of immunogenic West Nile virus-like particles using a herpes simplex virus 1 recombinant vector. (2016) (20)
Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs (2019) (20)
Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency (2021) (19)
Vedic Voices: Intimate Narratives of a Living Andhra Tradition (2015) (19)
Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells (2015) (19)
Decreasing Herpes Simplex Viral Infectivity in Solution by Surface-Immobilized and Suspended N,N-Dodecyl,methyl-polyethylenimine (2012) (18)
C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization. (2003) (17)
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner (2018) (16)
Herpes Simplex Virus Gene Products Required for Viral Inhibition of Expression of G 1-Phase Functions (2001) (16)
Hinduism: Experiments in the Sacred (1991) (16)
Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia (2019) (15)
Conformational Changes in the Herpes Simplex Virus ICP8 DNA-Binding Protein Coincident with Assembly in Viral Replication Structures (2003) (15)
Viral gene products actively promote latent infection by epigenetic silencing mechanisms. (2017) (15)
American Aid to Dumézil: A Critical Review of Recent Essays (1974) (14)
Combined cytotoxic activity of an infectious, but non‐replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells (2015) (13)
Clues to mechanisms of herpesviral latent infection and potential cures (2015) (12)
Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters (2015) (12)
In the Image of Fire Vedic Experiences of Heat (1975) (12)
A genetic test for expression of a functional herpes simplex virus DNA-binding protein from a transfected plasmid (1985) (12)
Intramuscular delivery of replication-defective herpes simplex virus gives antigen expression in muscle syncytia and improved protection against pathogenic HSV-2 strains. (2018) (12)
Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO) (2019) (11)
Ensuring vaccine safety (2020) (11)
Herpes simplex virus as a tool to define the role of complement in the immune response to peripheral infection. (2008) (11)
Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity (2020) (10)
The Heroic Theft: Myths from Ṛgveda IV and the Ancient near East (1967) (10)
Protection from genital herpes disease, seroconversion and latent infection in a non-lethal murine genital infection model by immunization with an HSV-2 replication-defective mutant virus. (2016) (10)
A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface (2021) (9)
Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes. (2021) (9)
Tissue-Resident-Memory CD8+ T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes (2021) (9)
Hindu Spirituality : Vedas Through Vedanta (1994) (9)
Comprar Fields Virology, 6e | Knipe | 9781451105636 | Lippincott Williams & Wilkins (2013) (8)
Vaccination Route as a Determinant of Protective Antibody Responses against Herpes Simplex Virus (2020) (8)
Characterization ofTwoConformational FormsoftheMajor DNA-Binding Protein Encoded byHerpes Simplex Virus 1 (1982) (8)
Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses (2021) (8)
Cell growth transformation by herpes simplex virus. (1982) (8)
SUPPLEMENTAL EXPERIMENTAL PROCEDURES (2012) (8)
Fundamental Virology, 4th Edition; and Fields Virology, 4th Edition, Volumes I and II:Fundamental Virology, 4th Edition;Fields Virology, 4th Edition, Volumes I and II (2002) (7)
Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA (2019) (7)
The use of green fluorescent fusion proteins to monitor herpes simplex virus replication. (2009) (7)
Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. (2002) (6)
The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity (2021) (6)
Herpes simplex virus U S 3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF 6 ubiquitination (2013) (6)
One Fire, Three Fires, Five Fires: Vedic Symbols in Transition (1972) (6)
Herpes Simplex Virus 1 Immediate-Early and Early Gene Expression during Reactivation from Latency under Conditions That Prevent Infectious Virus Production (2006) (6)
Genetic Influence from Chromosome 12 on Murine Susceptibility to Herpes Simplex Keratitis (1985) (5)
Rethinking the Response to Emerging Microbes: Vaccines and Therapeutics in the Ebola Era—a Conference at Harvard Medical School (2015) (5)
ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection (2021) (5)
Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH (2020) (4)
Herpes simplex virus vaccines. (2003) (4)
Virology under the Microscope—a Call for Rational Discourse (2023) (4)
Herpes Simplex Virus VP 16 , but Not ICP 0 , Is Required To Reduce Histone Occupancy and Enhance Histone Acetylation on Viral Genomes in U 2 OS Osteosarcoma Cells ! † (2010) (3)
Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity (2020) (3)
Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion (2003) (3)
Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses (2021) (3)
Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice (2021) (3)
Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. (1978) (3)
A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity (2021) (3)
Expression and Replication Promotes Herpes Simplex Virus 1 Immediate-Early Gene Cellular SNF 2 H Chromatin-Remodeling Factor 2011 (2011) (3)
Simian TRIM5 α Proteins Reduce Replication of Herpes Simplex Virus (2010) (2)
Herpesviridae: Herpes Simplex Virus 1 and 2 (HSV-1, HSV-2) (2020) (2)
Screening Method for CRISPR/Cas9 Inhibition of a Human DNA Virus: Herpes Simplex Virus. (2020) (2)
Replication Compartments of Eukaryotic and Bacterial DNA Viruses: Common Themes Between Different Domains of Host Cells. (2022) (2)
Immunity in C4-Deficient Mice Component C4 Can Restore Humoral Macrophage-Derived Complement (2002) (2)
Gene transfer to sensory neurons using herpes virus vectors. (1994) (2)
Human Cytomegalovirus UL 44 Concentrates 1 at the Periphery of Replication Compartments , 2 the Site of Viral DNA Synthesis 3 4 (2011) (1)
Virology under the Microscope—a Call for Rational Discourse (2023) (1)
virus alpha protein ICP27. transactivation functions of the herpes simplex Genetic evidence for two distinct (2013) (1)
Role of Protein Kinase A and the Serine-Rich Region of Herpes Simplex Virus Type 1 ICP 4 in Viral Replication (2005) (1)
Replication-Defective Herpes Simplex Virus Mutant Strains as Genital Herpes Vaccines and Vaccine Vectors (2011) (1)
Fields virology. 2nd edition. Vols 1 and 2. (1990) (1)
Rivalries inside out: Personal history and Possession Ritualism in Coastal Andhra (2005) (1)
CRISPR-Cas9 Expressed in Stably Transduced Cell Lines Promotes Recombination and Selects for Herpes Simplex Virus Recombinants. (2022) (1)
Virology under the Microscope—a Call for Rational Discourse (2023) (1)
Author response: ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress (2018) (1)
Interferon Production Mechanisms for Blocking Virus-Induced Herpes Simplex Virus 1 Has Multiple (2004) (1)
The lntranuclear Location of a Herpes Simplex Virus DNA-Binding Protein Is Determined by the Status of Viral DNA Replication (2004) (1)
USED AS PRIMERS AND PROBES IN THE AMPLIFICATION AND DETECTION OF SARS CORONAVIRUS (2017) (1)
Book Review:Asceticism and Healing in Ancient India: Medicine in the Buddhist Monastery Kenneth G. Zysk (1993) (1)
CIBLAGE DE L'INFECTION PAR LE VIRUS DE L'HERPÈS SIMPLEX DE TYPE 1 LYTIQUE ET LATENT PAR LA TECHNOLOGIE CRISPR/CAS9 (2018) (0)
Stimulation ofExpression ofaHerpesSimplex Virus DNA-Binding Protein byTwoViral Functions (1985) (0)
Annotated Bibliographies for Hinduism and Buddhist Religion (1984) (0)
Epitope specificity appears to be an important determinant of in vivo killing ability of simian immunodeficiency virus (SIV)-specific CD8+ T Cells (2012) (0)
Local synthesis of C3 in lymphoid tissues is sufficient to restore humoral responses to peripheral herpes simplex virus (HSV-1) infection in C3-deficient mice (2000) (0)
Review: The Myth of the Holy Cow (2004) (0)
Definition ofaSeries ofStages intheAssociation ofTwo Herpesviral Proteins withtheCellNucleus (1982) (0)
Immune protection against latent HSV-2 infection by a replication-defective mutant virus in a mouse model (1997) (0)
Owen County Transportation Vulnerability Study (2017) (0)
Virally delivered cytokine therapy drives immune equilibrium in melanoma (2020) (0)
CNBP controls c-Rel dependent IL-12β gene transcription and Th1 immunity (2018) (0)
CHROMATIN STRUCTURE OF THE HERPES SIMPLEX VIRUS 1 GENOME DURING LYTIC AND LATENT INFECTION (2012) (0)
Mapping of the Major Viral Glycoproteins and of the Genetic Loci (0)
Herpes Simplex Virus Immediate-Early ICP0 Protein Inhibits TLR2-dependent Inflammatory Responses and NF- κ B Signaling (2010) (0)
IFNγ is a central node of cancer immune equilibrium. (2023) (0)
Herpes Simplex Virus 1 and 2 (Herpesviridae) (2021) (0)
Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons - eScholarship (2005) (0)
Simian TRIM 5 α proteins reduce replication of herpes simplex virus (2010) (0)
A Viral Deamidase Targets the Helicase Domain of RIGI to Block RNA-Induced Activation Graphical (2016) (0)
Viral vaccines. Past, present and future (2003) (0)
Genetic and Molecular Analysis of Herpes Simplex Virus Assembly in vivo in Mouse Visual System Neurons (2005) (0)
Balancing raudra and śānti: Rage and repose in states of possession (2001) (0)
IFNγ from IL-12 virotherapy stably controls tumors independent of T cell cytotoxicity and IFNγ sensing by tumor cells (2022) (0)
Becoming a Householder (2015) (0)
Central Nervous System in Herpes Simplex Virus Infection of the Role of Specific Innate Immune Responses (2012) (0)
Herpes Simplex Virus 1 Glycoprotein B and US3 Collaborate To Inhibit CD1d Antigen Presentation and NKT Cell Function (cid:1) (2011) (0)
Identification ofa HerpesSimplex VirusFunction ThatRepresses LateGeneExpression fromParental Viral Genomes (1985) (0)
Mutations in the Major DNA-Binding Protein Gene Simplex (2003) (0)
A Tribute to Stephen E. Straus, M.D. (1946–2007) (2007) (0)
control of herpesvirus gene expression: Gene functions required for positive and negative regulation (herpes simplex virus/DNA-binding proteins/nuclear run-off transcription) (1986) (0)
The Strides of Vishnu: Hindu Culture in Historical Perspective. By Ariel Glucklich. New York: Oxford University Press, 2008. Pp. xiii+241, 2 plates. $29.95. (2010) (0)
Vedamlo, “Living in the Veda” (2015) (0)
Membrane Assembly : Synthesis and lntracellular Processing of the Vesicular Stomatitis Viral Glycoprotein Flora (2003) (0)
Becoming a Veda (2015) (0)
Chromatin Insulators and Nuclear Organization (2010) (0)
Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency (2021) (0)
Appendix 2. Draft Proposal for a Harvard Vaccine Institute (0)
[Application of herpes simplex virus to HIV vaccine vector]. (2006) (0)
HMS Task Force on Faculty Development and Diversity (2010) (0)
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner (2018) (0)
Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP 0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus (2005) (0)
Editorial Board (2016) (0)
Decreasing Herpes Simplex Viral Infectivity in Solution by Surface-Immobilized and Suspended N,N-Dodecyl,methyl-polyethylenimine (2012) (0)
A Selection of Ahitagni and Other Veda Pandits in Agrahara, Villages, and Towns (2015) (0)
Author response: Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 (2019) (0)
Herpes Simplex Virus VP16, but Not ICP0, Is Required To Reduce Histone Occupancy and Enhance Histone Acetylation on Viral Genomes in U2OS Osteosarcoma Cells (cid:1) † (2009) (0)
Mutations intheMajorDNA-Binding Protein Gene Simplex VirusType1Result inIncreased Levels GeneExpression ofHerpes ofViral (1983) (0)
Author ' s personal copy Herpesviruses (0)
Viral immune evasion: HSV-1 immediate early protein ICP0 inhibits TLR2-driven NF-kB activation (94.18) (2010) (0)
Selectively Regulates the Cytoplasmic Localization of a Subset of Viral Transcripts in Herpes Simplex Virus Type 1-Infected Cells (2003) (0)
A MutantHerpesvirus Protein LeadstoaBlockinNuclear Localization ofOtherViral Proteins (1986) (0)
Sayers, Matthew R.Feeding the Dead: Ancestor Worship in Ancient India. New York: Oxford University Press, 2013. xiv+187 pp. $99.00 (cloth); $29.95 (paper). (2016) (0)
The Godavari Delta (2015) (0)
Reviewed Work: Agni: The Vedic Ritual of the Fire Altar. by Frits Staal (1986) (0)
Guinea Pigs Simplex Virus 2 Infections in Mice and Glycoprotein , and DNA Vaccines for Herpes of Replication-Defective , Recombinant Comparative Efficacy and Immunogenicity (2004) (0)
IL-17c promotes peripheral nerve growth during human herpes simplex virus type 2 (HSV-2) infection (2017) (0)
A GENE FUNCTION OF HERPES SIMPLEX VIRUS REQUIRED FOR EXPRESSION OF ALL EARLY VIRAL GENES (1980) (0)
HerpesSimplex VirusAlphaProtein ICP27Possesses Separable Positive andNegative Regulatory Activities (1989) (0)
The Snake and the Mongoose: The Emergence of Identity in Early Indian Religion. By Nathan McGovern. New York: Oxford University Press, 2018. Pp. xiv+313. $99.00 (cloth); $31.27 (ebook). (2020) (0)
RNA Viruses the Interferon Response to both DNA and Interferon-stimulated Genes and Controls Interferons and Other Transcriptionally Regulates Type I-inducible Protein ( IFI ) 16 γ Interferon Immunology : (2014) (0)
Simplex Virus Infection Humoral Responses to Peripheral Herpes Myeloid C3 Determines Induction of (2003) (0)
Comparative Efficacy and Immunogenicity of Replication-Defective, Recombinant Glycoprotein, and DNA Vaccines for Herpes Simplex Virus 2 Infections in Mice and Guinea Pigs (2005) (0)
A Genetic TestforExpression ofaFunctional HerpesSimplex Virus DNA-Binding Protein fromaTransfected Plasmid (1985) (0)
Genetic Evidence forTwoDistinct Transactivation Functions ofthe HerpesSimplex Virus otProtein ICP27 (1990) (0)
Peripheral Viral Infection Enhances the Humoral Response To Cutting Edge: Myeloid Complement C3 (2001) (0)
Loss of the ITAM receptor CD200R1 attenuates HSV-1 infection and encephalitis. (68.15) (2012) (0)

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