James Bliska
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American molecular biologist
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Biology
James Bliska's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Molecular Biology Stanford University
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Why Is James Bliska Influential?
(Suggest an Edit or Addition)According to Wikipedia, James Bliska is an American molecular biologist, focusing on molecular mechanisms that underlie pathogenesis or host protection during host-microbe cell interactions, currently at Geisel School of Medicine and was Elected as Fellow at the American Association for the Advancement of Science in 2013.
James Bliska's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. (2005) (617)
- Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. (2000) (558)
- Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. (1999) (411)
- Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. (1991) (386)
- Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions (1997) (368)
- Signal transduction in the mammalian cell during bacterial attachment and entry (1993) (365)
- Yersinia pestis and the plague of Justinian 541-543 AD: a genomic analysis. (2014) (348)
- YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF‐α production and downregulation of the MAP kinases p38 and JNK (1998) (314)
- A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. (2010) (274)
- A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurlum (1996) (261)
- Use of site-specific recombination as a probe of DNA structure and metabolism in vivo. (1987) (252)
- Yops of Yersinia spp. pathogenic for humans (1993) (223)
- Turning Yersinia pathogenesis outside in: subversion of macrophage function by intracellular yersiniae. (2005) (212)
- The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence (2001) (209)
- The Yersinia Virulence Factor YopM Forms a Novel Protein Complex with Two Cellular Kinases* (2003) (190)
- Nucleotide sequence of the Yersinia enterocolitica ail gene and characterization of the Ail protein product (1990) (189)
- The Ability To Replicate in Macrophages Is Conserved between Yersinia pestis and Yersinia pseudotuberculosis (2003) (185)
- White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection (2017) (181)
- Bacterial resistance to complement killing mediated by the Ail protein of Yersinia enterocolitica. (1992) (168)
- The Yersinia pseudotuberculosis adhesin YadA mediates intimate bacterial attachment to and entry into HEp-2 cells (1993) (168)
- Cross-talk between bacterial pathogens and their host cells. (1996) (158)
- The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence (2000) (148)
- Inhibition of the Fc receptor-mediated oxidative burst in macrophages by the Yersinia pseudotuberculosis tyrosine phosphatase (1995) (147)
- A Process for Controlling Intracellular Bacterial Infections Induced by Membrane Injury (2004) (142)
- The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage (1992) (139)
- Inhibition of MAPK and NF-κB Pathways Is Necessary for Rapid Apoptosis in Macrophages Infected with Yersinia1 (2005) (139)
- The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome. (2016) (135)
- The Yersinia tyrosine phosphatase YopH targets a novel adhesion‐regulated signalling complex in macrophages (2000) (134)
- A bacterial type III secretion system inhibits actin polymerization to prevent pore formation in host cell membranes (2001) (132)
- Characterization of Phagosome Trafficking and Identification of PhoP-Regulated Genes Important for Survival of Yersinia pestis in Macrophages (2006) (127)
- Yersinia pestis Can Reside in Autophagosomes and Avoid Xenophagy in Murine Macrophages by Preventing Vacuole Acidification (2009) (127)
- Yersinia Virulence Depends on Mimicry of Host Rho-Family Nucleotide Dissociation Inhibitors (2006) (126)
- Surface organelles assembled by secretion systems of Gram-negative bacteria: diversity in structure and function. (2012) (125)
- The Response Regulator PhoP of Yersinia pseudotuberculosis Is Important for Replication in Macrophages and for Virulence (2004) (124)
- YopJ of Yersinia spp. Is Sufficient To Cause Downregulation of Multiple Mitogen-Activated Protein Kinases in Eukaryotic Cells (1999) (118)
- Replication of Yersinia pestis in interferon gamma-activated macrophages requires ripA, a gene encoded in the pigmentation locus. (2005) (108)
- Identification of an amino‐terminal substrate‐binding domain in the Yersinia tyrosine phosphatase that is required for efficient recognition of focal adhesion targets (1998) (105)
- Role of Toll-Like Receptor Signaling in the Apoptotic Response of Macrophages to Yersinia Infection (2003) (104)
- Yersinia Controls Type III Effector Delivery into Host Cells by Modulating Rho Activity (2008) (103)
- A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages (2011) (100)
- A Role for the SmpB-SsrA System in Yersinia pseudotuberculosis Pathogenesis (2006) (97)
- Proinflammatory signalling stimulated by the type III translocation factor YopB is counteracted by multiple effectors in epithelial cells infected with Yersinia pseudotuberculosis (2003) (96)
- Molecular evolution of intergenic DNA in higher primates: pattern of DNA changes, molecular clock, and evolution of repetitive sequences. (1988) (90)
- Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ (2008) (82)
- Aurintricarboxylic Acid Blocks in Vitro and in Vivo Activity of YopH, an Essential Virulent Factor of Yersinia pestis, the Agent of Plague* (2003) (81)
- Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 Production and Virulence (2010) (79)
- Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene. (1983) (77)
- Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection (2006) (69)
- Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors (2013) (66)
- IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM (2014) (65)
- Intracellular pathogenic bacteria and fungi — a case of convergent evolution? (2009) (65)
- Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis (2020) (65)
- CAS/Crk signalling mediates uptake of Yersinia into human epithelial cells (2000) (64)
- Yop effectors of Yersinia spp. and actin rearrangements. (2000) (58)
- The smpB-ssrA Mutant of Yersinia pestis Functions as a Live Attenuated Vaccine To Protect Mice against Pulmonary Plague Infection (2010) (58)
- Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents. (2012) (55)
- Identification of Residues in the N-terminal Domain of theYersinia Tyrosine Phosphatase That Are Critical for Substrate Recognition* (2001) (54)
- Cre-lox recombination in Escherichia coli cells. Mechanistic differences from the in vitro reaction. (1992) (54)
- Two substrate‐targeting sites in the Yersinia protein tyrosine phosphatase co‐operate to promote bacterial virulence (2005) (52)
- TNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague. (2010) (52)
- Distinct mechanisms of integrin binding by Yersinia pseudotuberculosis adhesins determine the phagocytic response of host macrophages (2005) (52)
- Role of macrophage apoptosis in the pathogenesis of Yersinia. (2005) (50)
- Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD (2015) (49)
- Type III Secretion Decreases Bacterial and Host Survival following Phagocytosis of Yersinia pseudotuberculosis by Macrophages (2008) (44)
- Role of Predicted Transmembrane Domains for Type III Translocation, Pore Formation, and Signaling by the Yersinia pseudotuberculosis YopB Protein (2005) (43)
- Global Gene Expression Profiling of Yersinia pestis Replicating inside Macrophages Reveals the Roles of a Putative Stress-Induced Operon in Regulating Type III Secretion and Intracellular Cell Division (2010) (42)
- YopJ-Induced Caspase-1 Activation in Yersinia-Infected Macrophages: Independent of Apoptosis, Linked to Necrosis, Dispensable for Innate Host Defense (2012) (42)
- Faculty Opinions recommendation of Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages. (2003) (40)
- CD11b+ Ly6Chi Ly6G− Immature Myeloid Cells Recruited in Response to Salmonella enterica Serovar Typhimurium Infection Exhibit Protective and Immunosuppressive Properties (2014) (40)
- Yersinia versus host immunity: how a pathogen evades or triggers a protective response. (2016) (40)
- Vaccination of Mice with a Yop Translocon Complex Elicits Antibodies That Are Protective against Infection with F1−Yersinia pestis (2008) (39)
- Biogenesis of the Fraction 1 Capsule and Analysis of the Ultrastructure of Yersinia pestis (2008) (38)
- TNFα and IFNγ but Not Perforin Are Critical for CD8 T Cell-Mediated Protection against Pulmonary Yersinia pestis Infection (2014) (36)
- A Transposon Site Hybridization Screen Identifies galU and wecBC as Important for Survival of Yersinia pestis in Murine Macrophages (2011) (35)
- Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components (2017) (33)
- YopJ-Promoted Cytotoxicity and Systemic Colonization Are Associated with High Levels of Murine Interleukin-18, Gamma Interferon, and Neutrophils in a Live Vaccine Model of Yersinia pseudotuberculosis Infection (2010) (30)
- Interleukin-10 Induction Is an Important Virulence Function of the Yersinia pseudotuberculosis Type III Effector YopM (2012) (29)
- Yersinia inhibits host signaling by acetylating MAPK kinases. (2006) (28)
- A Protective Epitope in Type III Effector YopE Is a Major CD8 T Cell Antigen during Primary Infection with Yersinia pseudotuberculosis (2011) (27)
- The role of host tyrosine phosphorylation in bacterial pathogenesis. (1993) (27)
- LcrV Capture Enzyme-Linked Immunosorbent Assay for Detection of Yersinia pestis from Human Samples (2005) (27)
- CCR2+ Inflammatory Monocytes Are Recruited to Yersinia pseudotuberculosis Pyogranulomas and Dictate Adaptive Responses at the Expense of Innate Immunity during Oral Infection (2017) (26)
- Uncovering an Important Role for YopJ in the Inhibition of Caspase-1 in Activated Macrophages and Promoting Yersinia pseudotuberculosis Virulence (2016) (25)
- Yersinia pestis Can Bypass Protective Antibodies to LcrV and Activation with Gamma Interferon To Survive and Induce Apoptosis in Murine Macrophages (2009) (24)
- Mechanism of Tn3 resolvase recombination in vivo. (1991) (24)
- The pyrin inflammasome in host-microbe interactions. (2020) (24)
- Inflammatory monocytes provide a niche for Salmonella expansion in the lumen of the inflamed intestine (2019) (24)
- Characterization of Pyrin Dephosphorylation and Inflammasome Activation in Macrophages as Triggered by the Yersinia Effectors YopE and YopT (2019) (24)
- Epidemiology of Pathogenic Enterobacteria in Humans, Livestock, and Peridomestic Rodents in Rural Madagascar (2014) (23)
- How pathogens exploit interactions mediated by SH3 domains. (1996) (22)
- Type III Secretion System-Dependent Translocation of Ectopically Expressed Yop Effectors into Macrophages by Intracellular Yersinia pseudotuberculosis (2011) (21)
- Measurement of pore formation by contact-dependent type III protein secretion systems. (2002) (20)
- Structural insights into RipC, a putative citrate lyase β subunit from a Yersinia pestis virulence operon. (2012) (16)
- Direct Neutralization of Type III Effector Translocation by the Variable Region of a Monoclonal Antibody to Yersinia pestis LcrV (2014) (16)
- The GAP Activity of Type III Effector YopE Triggers Killing of Yersinia in Macrophages (2014) (16)
- Microbial pathogenesis and tyrosine dephosphorylation: surprising‘bedfellows' (1991) (15)
- Biochemical, Structural and Molecular Dynamics Analyses of the Potential Virulence Factor RipA from Yersinia pestis (2011) (15)
- Analysis of amplified DNAs from drug-resistant Leishmania by orthogonal-field-alternation gel electrophoresis. The effect of size and topology on mobility. (1989) (14)
- Salmonella “Sops” Up a Preferred Electron Receptor in the Inflamed Intestine (2012) (14)
- Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions (2021) (13)
- A Single Amino Acid Change in the Response Regulator PhoP, Acquired during Yersinia pestis Evolution, Affects PhoP Target Gene Transcription and Polymyxin B Susceptibility (2018) (13)
- The pyrin inflammasome and the Yersinia effector interaction (2020) (13)
- Roles of Chaperone/Usher Pathways of Yersinia pestis in a Murine Model of Plague and Adhesion to Host Cells (2012) (12)
- CCR2+ Inflammatory Dendritic Cells and Translocation of Antigen by Type III Secretion Are Required for the Exceptionally Large CD8+ T Cell Response to the Protective YopE69-77 Epitope during Yersinia Infection (2015) (11)
- Pathogen antigen- and superantigen-reactive synovial fluid T cells in reactive arthritis. (1995) (10)
- Interplay between determinants of cellular entry and cellular disruption in the enteropathogenic Yersinia (1994) (10)
- Effector CD8+ T Cells Are Generated in Response to an Immunodominant Epitope in Type III Effector YopE during Primary Yersinia pseudotuberculosis Infection (2014) (9)
- Effects of host cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered β1 integrin (2017) (7)
- The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection (2021) (6)
- Yops of the Pathogenic Yersinia spp. (1994) (5)
- Random Mutagenesis Identifies a C-Terminal Region of YopD Important for Yersinia Type III Secretion Function (2015) (5)
- Mathematical relationship between cytokine concentrations and pathogen levels during infection. (2011) (5)
- The Importance of Role Models in Research (2016) (4)
- Rabbit monoclonal antibodies directed at the T3SS effector protein YopM identify human pathogenic Yersinia isolates. (2014) (4)
- Type III Secretion Systems in Yersinia pestis and Yersinia pseudotuberculosis (2006) (4)
- A blend of broadly-reactive and pathogen-selected Vγ4Vδ1 T cell receptors confer broad bacterial reactivity of resident memory γδ T cells (2021) (4)
- How Yersinia pestis becomes a foreign obstruction in the digestive system of the macrophage (2009) (3)
- Intestinal Bacteroides Modulates Systemic Inflammation and the Microbial Ecology in a Mouse Model of CF: Evidence for Propionate and other Short Chain Fatty Acids Reducing Systemic Inflammatory Cytokines (2022) (2)
- Genetics of bacterial virulence (1995) (2)
- Letter to the Editor and response (2011) (2)
- Role of the Yersinia pseudotuberculosis Virulence Plasmid in Pathogen-Phagocyte Interactions in Mesenteric Lymph Nodes (2021) (2)
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins (2022) (2)
- Yop effectors of Yersinia spp. and (2000) (2)
- Inhibition of the macrophage Fc receptor-mediated oxidative burst by the Yersinia pseudotuberculosis tyrosine phosphatase (1995) (1)
- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages (2010) (1)
- Precursor abundance influences divergent antigen specific CD8+ T cell responses after Yersinia pseudotuberculosis foodborne infection (2021) (1)
- Essential role for CCR2+ inflammatory monocytes in early and late control of persistent Salmonella infection (INC2P.412) (2015) (1)
- Methods for Detection of Pyrin Inflammasome Assembly in Macrophages Infected with Yersinia spp. (2019) (1)
- Faculty Opinions recommendation of Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. (2004) (1)
- A blend of broadly-reactive and pathogen-selected Vγ4 Vδ1 T cell receptors confer broad bacterial reactivity of resident memory γδ T cells (2021) (1)
- γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans (2021) (1)
- PLOS Pathogens 2016 Reviewer and Editorial Board Thank You (2017) (1)
- Bacterial Toxins that Modulate Rho GTPase Activity (2003) (1)
- Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes (2022) (0)
- The Yerslnia Tyrosine Phosphatase : Specificity of a Bacterial Virulence Detetiitinant for Phosphoproteins in the J 774 A . 1 Macrophage By (2003) (0)
- Faculty Opinions recommendation of Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cells. (2011) (0)
- The Burkholderia cenocepacia type VI secretion system effector TecA is a virulence factor during lung infection (2021) (0)
- Crystal structure of the Yersivlia tyrosine phosphatase (1995) (0)
- Faculty Opinions recommendation of Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. (2004) (0)
- Faculty Opinions recommendation of Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking. (2011) (0)
- Pathogen-elicited memory γδ T cells express a broadly reactive canonical TCR or a pathogen-specific non-canonical TCR (2020) (0)
- Adaptive γδ T cell function is directly subverted by the Yersinia pseudotuberculosis outer protein YopJ (2021) (0)
- Acknowledgment to reviewers (2018) (0)
- Sterol effect upon Yersinia internalization 1 Effects of host cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered beta-1 integrin (2017) (0)
- NOTES Biogenesis of the Fraction 1 Capsule and Analysis of the Ultrastructure of Yersinia pestis (cid:1) (2008) (0)
- Immunofluorescence studies comparing YopH localization in HeLa and J774A1 cells infected with different Yersinia pseudotuberculosis strains (1996) (0)
- Co-crystal structure of YpkA-Rac1 (2006) (0)
- Imaging Regulatory Lipids and Protein Kinase C at Sites of Exocytosis (2017) (0)
- Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins (2022) (0)
- Adaptive γδ T cell function is subverted by Yersinia pseudotuberculosis outer proteins (2020) (0)
- Faculty Opinions recommendation of Rafts can trigger contact-mediated secretion of bacterial effectors via a lipid-based mechanism. (2004) (0)
- Correction: γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans (2022) (0)
- Gut Check: IFNγ Delays Mucosal Recovery during Antibiotic Therapy. (2016) (0)
- Referees 1997 (1997) (0)
- 20 Effector proteins of bacterial type III protein secretion systems: Elucidating their biochemical effects on eukaryotic signaling cascades (2002) (0)
- Effects of Sterol Substitution in Plasma Membrane of Host Cell upon Internalization of Yersinia Pseudotuberculosis (2017) (0)
- Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites (2005) (0)
- Correction: Random Mutagenesis Identifies a C-Terminal Region of YopD Important for Yersinia Type III Secretion Function (2015) (0)
- Faculty Opinions recommendation of Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation. (2007) (0)
- Crystal structure of the Rho-GTPase binding domain of YpkA (2006) (0)
- Table of Contents (2014) (0)
- Referees 1998 (1998) (0)
- Vacuole Acidification Murine Macrophages by Preventing Autophagosomes and Avoid Xenophagy in Can Reside in (2014) (0)
- Human pathogenic Yersinia species (2009) (0)
- Faculty Opinions recommendation of The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. (2009) (0)
- Faculty Opinions recommendation of Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. (2006) (0)
- Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites (2005) (0)
- Precursor Abundance Influences Divergent Antigen-Specific CD8+ T Cell Responses after Yersinia pseudotuberculosis Foodborne Infection (2021) (0)
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