Richard Houlston

Q: What Schools Are Affiliated With Richard Houlston

Richard Houlston is affiliated with the following schools: Institute of Cancer Research, Imperial College London, University of Oxford, Hannover Medical School, Sorbonne University, University of Helsinki

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Richard Houlston

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#1193

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#55

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#172

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#184

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Richard Houlston

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#5151

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#477

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#488

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#521

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Richard Houlston's Degrees

Bachelors Biochemistry University of Oxford
PhD Molecular Biology University of Oxford

Why Is Richard Houlston Influential?

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According to Wikipedia, Richard Somerset Houlston is a British medical geneticist. He is a professor of molecular and population genetics at the Institute of Cancer Research in London. Education Houlston graduated BSc, MB BS from Charing Cross Hospital Medical School, University of London and was subsequently awarded MD and PhD degrees from the University of London and a DSc from Imperial College, London.

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Richard Houlston's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Systematic review of microsatellite instability and colorectal cancer prognosis. (2005) (1672)
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer (2002) (1329)
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 (2008) (1262)
Mutations in the SMAD4/DPC4 gene in juvenile polyposis. (1998) (946)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis (2012) (864)
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations (2002) (860)
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21 (2007) (838)
Genome-wide association study identifies five susceptibility loci for glioma (2009) (781)
A systematic review and meta-analysis of familial colorectal cancer risk (2001) (752)
Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome (2006) (743)
Genome-wide association study identifies five new breast cancer susceptibility loci (2010) (716)
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (2008) (629)
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer (2008) (599)
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 (2008) (578)
Common 5p15.33 and 6p21.33 variants influence lung cancer risk (2008) (550)
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. (2009) (532)
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk (2007) (528)
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling (2009) (520)
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (2013) (519)
Germline mutations in the proof-reading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (2012) (487)
Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. (2004) (468)
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia (2009) (456)
Mutations in PTF1A cause pancreatic and cerebellar agenesis (2004) (413)
Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD (2010) (400)
Diagnostic criteria for monoclonal B‐cell lymphocytosis (2005) (395)
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33 (2010) (391)
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia (2008) (380)
Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis (2008) (355)
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes (2017) (353)
Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic (2020) (349)
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 (2010) (341)
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (2014) (322)
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk (2008) (320)
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome (2011) (308)
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 (2009) (305)
Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study (2020) (296)
A systematic review and meta‐analysis of familial prostate cancer risk (2003) (289)
Systematic review of the relationship between family history and lung cancer risk (2005) (275)
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. (2011) (263)
Common variants at 19p13 are associated with susceptibility to ovarian cancer (2010) (262)
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors. (2011) (260)
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. (2001) (255)
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk (2010) (253)
Polymorphisms and colorectal tumor risk. (2001) (251)
Genome-wide association studies of cancer: current insights and future perspectives (2017) (245)
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. (2009) (244)
Common variants at 2q37.3, 8q24.21, 15q21.3, and 16q24.1 influence chronic lymphocytic leukemia risk (2010) (243)
Relative frequency and morphology of cancers in STK11 mutation carriers. (2004) (241)
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk (2012) (234)
Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion. (2002) (234)
Gene for arrhythmogenic right ventricular cardiomyopathy with diffuse nonepidermolytic palmoplantar keratoderma and woolly hair (Naxos disease) maps to 17q21. (1998) (232)
Primary small-bowel malignancy in the UK and its association with coeliac disease. (2003) (225)
Genome-wide association study of glioma and meta-analysis (2012) (225)
The search for low-penetrance cancer susceptibility alleles (2004) (219)
Architecture of inherited susceptibility to common cancer (2010) (217)
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer (2012) (213)
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors (2017) (213)
Peutz-Jeghers syndrome. (1997) (210)
Explaining the Familial Colorectal Cancer Risk Associated with Mismatch Repair (MMR)-Deficient and MMR-Stable Tumors (2007) (206)
Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer (2011) (204)
Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer. (1997) (203)
Clinical implications of the colorectal cancer risk associated with MUTYH mutation. (2009) (199)
Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency (2006) (198)
Low-level microsatellite instability in most colorectal carcinomas. (2002) (197)
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls (2012) (196)
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci (2015) (194)
A genome-wide association study of Hodgkin Lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21, and 10p14 (GATA3) (2010) (194)
Contribution of the MHC region to the familial risk of coeliac disease (1999) (189)
A systematic review and meta-analysis of the relationship between chromosome 18q genotype, DCC status and colorectal cancer prognosis. (2005) (186)
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia (2013) (183)
Further observations on LKB1/STK11 status and cancer risk in Peutz–Jeghers syndrome (2003) (174)
Germline mutations in shelterin complex genes are associated with familial glioma. (2015) (167)
TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis. (2003) (166)
Familial defective apolipoprotein B-100: detection in the United Kingdom and Scandinavia, and clinical characteristics of ten cases. (1990) (166)
Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma. (2017) (166)
Chromosome 7p11.2 (EGFR) variation influences glioma risk. (2011) (161)
Germline PTEN mutations in Cowden syndrome-like families. (1998) (157)
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. (2008) (157)
Genetics of coeliac disease. (1996) (157)
Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. (2002) (156)
Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk (2011) (155)
TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations (2014) (153)
Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours (2015) (151)
Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. (1998) (151)
Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q. (2000) (151)
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk (2013) (150)
Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients (2017) (150)
Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. (2001) (149)
Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC) (2007) (145)
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. (2013) (144)
Exon 3 β-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome (2005) (143)
Screening and genetic counselling for relatives of patients with colorectal cancer in a family cancer clinic. (1990) (143)
Dominant genes for colorectal cancer are not rare (1992) (143)
Glutathione S-transferase M1 status and lung cancer risk: a meta-analysis. (1999) (140)
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. (2014) (139)
Family history and risk of breast cancer. (1992) (139)
Genome-wide association study identifies multiple susceptibility loci for multiple myeloma (2016) (136)
Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals (2012) (133)
Association analyses identify 31 new risk loci for colorectal cancer susceptibility (2019) (132)
Genetic predisposition to mosaic Y chromosome loss in blood (2019) (131)
Comprehensive analysis of the contribution of germline MYH variation to early‐onset colorectal cancer (2004) (130)
Familial chronic lymphocytic leukaemia: a survey and review of published studies (2000) (130)
CYP1A1 polymorphisms and lung cancer risk: a meta-analysis. (2000) (130)
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. (2010) (129)
Analysis of genetic and phenotypic heterogeneity in juvenile polyposis (2000) (128)
Putative cis-regulatory drivers in colorectal cancer (2014) (128)
Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis (2010) (128)
Universal weekly testing as the UK COVID-19 lockdown exit strategy (2020) (127)
Genetics and the common cancers. (2001) (123)
Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility. (2007) (121)
Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study (2015) (119)
Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival. (2010) (119)
Variants in the GH-IGF axis confer susceptibility to lung cancer. (2006) (119)
The future of association studies of common cancers (2003) (117)
Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukemia. (2006) (117)
IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. (2018) (117)
Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22. (1999) (116)
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants (2010) (113)
Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer (2016) (112)
A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer (2015) (111)
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium. (2000) (111)
MTHFR C677T and colorectal cancer risk: A meta‐analysis of 25 populations (2006) (111)
International Lung Cancer Consortium: Pooled Analysis of Sequence Variants in DNA Repair and Cell Cycle Pathways (2008) (110)
Genome-wide association study identifies multiple susceptibility loci for glioma (2015) (107)
Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers. (2010) (107)
The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. (2009) (107)
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor (2017) (104)
Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer (2002) (104)
BRAF mutations are detectable in conjunctival but not uveal melanomas (2004) (104)
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression. (2009) (102)
Linkage analysis of candidate regions for coeliac disease genes. (1997) (101)
A family with isolated hyperparathyroidism segregating a missense MEN1 mutation and showing loss of the wild-type alleles in the parathyroid tumors. (1998) (101)
BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years (2012) (98)
Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer. (2001) (98)
The CCND1 870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma (2013) (95)
ATM polymorphisms as risk factors for prostate cancer development (2004) (92)
National study of colorectal cancer genetics (2007) (92)
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome. (2009) (91)
Folate and colorectal cancer prevention (2008) (89)
GLIOGENE—an International Consortium to Understand Familial Glioma (2007) (88)
Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H (2010) (88)
Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes (2002) (87)
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. (2016) (87)
Genome-wide association study identifies multiple risk loci for renal cell carcinoma (2017) (86)
Genome-wide association study on differentiated thyroid cancer. (2013) (84)
A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia. (2007) (83)
Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. (2015) (83)
Genetic advances in glioma: susceptibility genes and networks. (2010) (82)
Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review. (2017) (82)
The Silver syndrome variant of hereditary spastic paraplegia maps to chromosome 11q12-q14, with evidence for genetic heterogeneity within this subtype. (2001) (82)
Genetic variation in the DNA repair genes is predictive of outcome in lung cancer. (2007) (82)
Relationship between glutathione S-transferase M1, T1, and P1 polymorphisms and chronic lymphocytic leukemia. (2002) (81)
What we could do now: molecular pathology of colorectal cancer (2001) (81)
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. (2012) (81)
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2018) (81)
Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma. (2011) (81)
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11 q 23 and replicates risk loci at 8 q 24 and 18 q 21 (2009) (80)
A high-density SNP genomewide linkage scan for chronic lymphocytic leukemia-susceptibility loci. (2005) (80)
Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D (2020) (80)
Cancer genetics, precision prevention and a call to action (2018) (80)
Activating mutations and/or expression levels of tyrosine kinase receptors GRB7, RAS, and BRAF in testicular germ cell tumors. (2005) (79)
Anticipation in familial chronic lymphocytic leukaemia (1998) (79)
Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan. (2006) (78)
Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study (2016) (78)
Association between genetic variation at the APO AI‐CIII‐AIV gene cluster and familial combined hyperlipidaemia (1994) (78)
Comprehensive analysis of the role of DNA repair gene polymorphisms on risk of glioma. (2008) (78)
Unregulated smooth-muscle myosin in human intestinal neoplasia (2008) (77)
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia (2017) (77)
Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition (2006) (75)
Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas (2002) (75)
Catabolic rate of low density lipoprotein is influenced by variation in the apolipoprotein B gene. (1988) (74)
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. (2008) (73)
Modifier genes in humans: strategies for identification (1998) (73)
CHEK2 variants in susceptibility to breast cancer and evidence of retention of the wild type allele in tumours (2002) (72)
Microarray comparative genomic hybridisation analysis of intraocular uveal melanomas identifies distinctive imbalances associated with loss of chromosome 3 (2005) (72)
Screening SMAD1,SMAD2, SMAD3, andSMAD5 for germline mutations in juvenile polyposis syndrome (1999) (72)
Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis (2017) (72)
Inherited genetic susceptibility to multiple myeloma (2014) (71)
Colorectal cancer risk in monoallelic carriers of MYH variants. (2006) (71)
Implications of polygenic risk for personalised colorectal cancer screening. (2016) (71)
Interobserver agreement in grading of colorectal cancers—findings from a nationwide web‐based survey of histopathologists (2008) (71)
Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort (2009) (71)
A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer. (2006) (71)
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer. (2003) (70)
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1 q 41 , 3 q 26 . 2 , 12 q 13 . 13 and 20 q 13 (2010) (70)
Further evidence that germline CEBPA mutations cause dominant inheritance of acute myeloid leukaemia (2005) (70)
Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma. (2003) (69)
Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers. (2001) (69)
Glutathione S-transferase μ1 (GSTM1) status and bladder cancer risk : a meta-analysis (2000) (69)
A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1. (2001) (69)
Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives. (2006) (68)
Risk of cancer death in first‐degree relatives of patients with hereditary non‐polyposis cancer syndrome (Lynch type II): A study of 130 kindreds in the United Kingdom (1990) (68)
Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer (2017) (68)
Effective lipid lowering diets including lean meat (1988) (68)
Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes (2001) (67)
Shared heritability and functional enrichment across six solid cancers (2018) (67)
Low frequency of germline E-cadherin mutations in familial and nonfamilial gastric cancer (1999) (66)
Genetic susceptibility to chronic lymphocytic leukemia (2002) (65)
Immunohistochemistry for MSH2 and MHL1: a method for identifying mismatch repair deficient colorectal cancer (2001) (65)
Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin’s Lymphoma (2013) (65)
Serum Lipids and Lipoproteins in Insulin‐dependent Diabetic Patients with Persistent Microalbuminuria (1989) (65)
Cholesterol and atherosclerosis. (1988) (65)
Five endometrial cancer risk loci identified through genome-wide association analysis (2016) (64)
Association of Genetic Variants at 8q24 with Breast Cancer Risk (2008) (63)
Functional Polymorphisms in Folate Metabolism Genes Influence the Risk of Meningioma and Glioma (2008) (63)
Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk (2007) (63)
Genomewide linkage searches for Mendelian disease loci can be efficiently conducted using high-density SNP genotyping arrays. (2004) (63)
Increasing evidence that germline mutations in CHEK2 do not cause Li‐Fraumeni syndrome (2002) (62)
Genetic Risk Profiles Identify Different Molecular Etiologies for Glioma (2010) (62)
Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome (2005) (62)
Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes. (2011) (61)
Genome-wide association study identifies a novel variant in RAD51B associated with male breast cancer risk (2012) (61)
A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers (2006) (61)
Role of 657del5 NBN mutation and 7p12.2 (IKZF1), 9p21 (CDKN2A), 10q21.2 (ARID5B) and 14q11.2 (CEBPE) variation and risk of childhood ALL in the Polish population. (2011) (61)
Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom. (2006) (61)
HLA Associations in Classical Hodgkin Lymphoma: EBV Status Matters (2012) (60)
Genetic epidemiology of ovarian cancer: segregation analysis (1991) (59)
Carney complex, Peutz-Jeghers syndrome, Cowden disease, and Bannayan-Zonana syndrome share cutaneous and endocrine manifestations, but not genetic loci. (1998) (59)
Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer. (2013) (59)
Comprehensive analysis of DNA repair gene variants and risk of meningioma. (2008) (59)
The fractional catabolic rate of low density lipoprotein in normal individuals is influenced by variation in the apolipoprotein B gene: a preliminary study. (1988) (59)
A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1 (2016) (58)
Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3 (2008) (58)
Causation of chronic lymphocytic leukemia--insights from familial disease. (2003) (58)
The TERT variant rs2736100 is associated with colorectal cancer risk (2012) (57)
Whole-genome sequencing of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms (2018) (57)
Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. (2015) (57)
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease (2002) (57)
Risk of Second Cancer in Hodgkin Lymphoma Survivors and Influence of Family History (2017) (57)
Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma. (2012) (56)
CASP8 variants D302H and −652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population (2008) (56)
Two hits revisited again (2001) (56)
Association between hormonal genetic polymorphisms and early-onset prostate cancer (2005) (56)
Interaction between 5 genetic variants and allergy in glioma risk. (2010) (55)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2019) (55)
Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies. (2013) (55)
The silent mutational landscape of infant MLL‐AF4 pro‐B acute lymphoblastic leukemia (2013) (54)
Generation of Artificial FASTQ Files to Evaluate the Performance of Next-Generation Sequencing Pipelines (2012) (53)
Germ line mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia. (2016) (53)
Modifiable pathways for colorectal cancer: a mendelian randomisation analysis (2019) (52)
Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. (2016) (52)
Common variation at 10p12.31 near MLLT10 influences meningioma risk (2011) (52)
Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. (2008) (52)
Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study (2020) (52)
Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222 (2013) (52)
Inherited genetic susceptibility to monoclonal B-cell lymphocytosis. (2010) (51)
The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study (2019) (51)
Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism (2016) (51)
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk (2018) (51)
Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches (2015) (50)
N‐acetyl transferase‐2 and bladder cancer risk: A meta‐analysis (2000) (50)
Replication study of SNP associations for colorectal cancer in Hong Kong Chinese (2010) (50)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (50)
Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia (2013) (50)
Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study (2018) (50)
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2009) (50)
Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS) (2008) (49)
Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence (2010) (49)
Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast (2014) (49)
Prevalence of the APC E1317Q variant in colorectal cancer patients. (2000) (49)
PTEN mutations are uncommon in Proteus syndrome (2001) (49)
Deciphering the 8q24.21 association for glioma. (2013) (49)
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer (2016) (49)
A robust method for detecting CHK2/RAD53 mutations in genomic DNA (2002) (49)
STK11 status and intussusception risk in Peutz-Jeghers syndrome (2006) (48)
SNPLINK: multipoint linkage analysis of densely distributed SNP data incorporating automated linkage disequilibrium removal (2005) (48)
The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium. (2015) (48)
Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene. (2018) (48)
Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms (2014) (47)
Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups (2017) (47)
HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease (2002) (47)
The phenotype of Floating–Harbor syndrome in 10 patients (2010) (46)
The C/C−13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population (2005) (46)
A novel gene for neonatal diabetes maps to chromosome 10p12.1-p13. (2003) (46)
Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma (2003) (46)
Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men (2011) (45)
Disparity between apolipoprotein E phenotypes and genotypes (as determined by polymerase chain reaction and oligonucleotide probes) in patients with non-insulin-dependent diabetes mellitus. (1991) (45)
The Common D302H Variant of CASP8 Is Associated with Risk of Glioma (2008) (45)
Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer (2018) (45)
Collateral damage: the impact on cancer outcomes of the COVID-19pandemic (2020) (44)
Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom. (2009) (44)
The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression (2017) (44)
Folate Metabolism Polymorphisms Influence Risk of Colorectal Adenoma Recurrence (2006) (44)
Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium. (2011) (44)
The Predicted Impact of Coding Single Nucleotide Polymorphisms Database (2005) (43)
Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis (2007) (43)
Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk (2019) (43)
TCF12 is mutated in anaplastic oligodendroglioma (2015) (43)
Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia (2012) (42)
Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk (2010) (42)
New insights into susceptibility to glioma. (2010) (42)
Diffuse gliomas classified by 1p/19q co-deletion, TERT promoter and IDH mutation status are associated with specific genetic risk loci (2018) (42)
Analysis of 153,115 patients with hematological malignancies refines the spectrum of familial risk. (2019) (42)
visPIG - A Web Tool for Producing Multi-Region, Multi-Track, Multi-Scale Plots of Genetic Data (2014) (42)
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 (2018) (41)
Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia (2011) (41)
Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer (2002) (41)
Ornithine Decarboxylase G316A Genotype Is Prognostic for Colorectal Adenoma Recurrence and Predicts Efficacy of Aspirin Chemoprevention (2008) (41)
The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4 (2012) (41)
Monoclonal B-cell lymphocytosis (MBL) in CLL families: substantial increase in relative risk for young adults (2006) (41)
Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3. (2011) (41)
Genome screening of coeliac disease (2002) (40)
A Cancer-associated Aurora A Mutant Is Mislocalized and Misregulated Due to Loss of Interaction with TPX2* (2009) (40)
Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk. (2010) (40)
Genetics of non-medullary thyroid cancer. (1995) (40)
Germ line mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia. (2016) (40)
Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene (2000) (40)
Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk (2011) (39)
Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta‐Analysis of Three Genome‐Wide Association Studies (2017) (39)
A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer (2016) (39)
Genetic predisposition to ocular melanoma (1999) (39)
MLH1-93G > A is a risk factor for MSI colorectal cancer. (2011) (39)
Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients. (2007) (39)
Analysis of the CTLA4 Gene in Swedish Coeliac Disease Patients (2002) (39)
Linkage analysis for ATM in familial B cell chronic lymphocytic leukaemia (1999) (39)
Is the E133K allele of VG5Q associated with Klippel-Trenaunay and other overgrowth syndromes? (2005) (39)
Analysis of the Fanconi Anaemia Complentation Group A Gene in Acute Myeloid Leukaemia (2002) (39)
Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis. (2008) (38)
Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene. (2003) (38)
Distinct Genetic and Epigenetic Changes in Medullary Breast Cancer (2003) (38)
Inherited variation in immune genes and pathways and glioblastoma risk (2010) (38)
Identification of four new susceptibility loci for testicular germ cell tumour (2015) (38)
Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK. (2009) (38)
Contribution of the CHEK2 1100delC variant to risk of multiple colorectal adenoma and carcinoma. (2003) (37)
Molecular advances in medullary thyroid cancer diagnostics. (2006) (37)
Deciphering the genetics of hereditary non-syndromic colorectal cancer (2008) (37)
MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer. (2007) (37)
Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 (2017) (37)
Inherited genetic susceptibility to monoclonal gammopathy of unknown significance. (2014) (36)
Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients. (2002) (36)
Comprehensive evaluation of the impact of 14 genetic variants on colorectal cancer phenotype and risk. (2012) (36)
Risk of breast and prostate cancer is not associated with increased homozygosity in outbred populations (2010) (36)
Genetic susceptibility to gluten sensitive enteropathy in Irish setter dogs is not linked to the major histocompatibility complex. (1998) (36)
ATM mutations are rare in familial chronic lymphocytic leukemia. (2002) (36)
Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2 (2017) (36)
Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma. (2017) (35)
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease (2016) (35)
Evaluation of Germline BMP4 Mutation as a Cause of Colorectal Cancer (2011) (35)
Genomic landscape of platinum resistant and sensitive testicular cancers (2020) (35)
Genetic evidence that the putative receptor binding domain of apolipoprotein B (residues 3130 to 3630) is not the only region of the protein involved in interaction with the low density lipoprotein receptor. (1991) (35)
Description of selected characteristics of familial glioma patients - results from the Gliogene Consortium. (2013) (35)
Familial chronic lymphocytic leukemia. (2006) (34)
COGENT (COlorectal cancer GENeTics) revisited. (2012) (34)
Whole-Genome Amplification by Degenerate Oligonucleotide Primed PCR (DOP-PCR). (2008) (34)
Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk (2008) (34)
Telomere structure and maintenance gene variants and risk of five cancer types (2016) (34)
Lack of an Association between the TGFBR1*6A Variant and Colorectal Cancer Risk (2007) (34)
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci (2017) (34)
Genetic Variants of UGT1A6 Influence Risk of Colorectal Adenoma Recurrence (2006) (34)
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence (2008) (33)
A retrospective observational study of the relationship between family history and survival from colorectal cancer (2013) (33)
Evidence for an Association between Compound Heterozygosity for Germ Line Mutations in the Hemochromatosis (HFE) Gene and Increased Risk of Colorectal Cancer (2005) (33)
Implications of familial colorectal cancer risk profiles and microsatellite instability status. (2009) (33)
Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia (2014) (33)
CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers (2001) (33)
Haemochromatosis gene mutations in idiopathic dilated cardiomyopathy (2000) (33)
Quantifying the heritability of glioma using genome-wide complex trait analysis (2015) (33)
Mutational processes contributing to the development of multiple myeloma (2019) (32)
Glutathione S-transferase mu1 (GSTM1) status and bladder cancer risk: a meta-analysis. (2000) (32)
No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome (2010) (32)
Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma (2016) (32)
Prognostic significance of folate metabolism polymorphisms for lung cancer (2007) (32)
Weekly COVID-19 testing with household quarantine and contact tracing is feasible and would probably end the epidemic (2020) (32)
Investigation of the effects of DNA repair gene polymorphisms on the risk of colorectal cancer. (2012) (32)
Identification of the cystic fibrosis gene. (1990) (32)
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1 (2015) (32)
Insight into the pathogenesis of chronic lymphocytic leukemia (CLL) through analysis of IgVH gene usage and mutation status in familial CLL. (2008) (32)
The use of whole genome amplification to study chromosomal changes in prostate cancer: insights into genome-wide signature of preneoplasia associated with cancer progression (2006) (32)
Detecting low penetrance genes in cancer: the way ahead (2000) (32)
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2017) (32)
The P2X7 receptor gene A1513C polymorphism does not contribute to risk of familial or sporadic chronic lymphocytic leukemia. (2004) (31)
Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma (2017) (31)
Association analysis using next-generation sequence data from publicly available control groups: the robust variance score statistic (2014) (31)
Mapping of a translocation breakpoint in a Peutz–Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11‐negative PJS cases (2004) (31)
Modeling the prevention of colorectal cancer from the combined impact of host and behavioral risk factors (2016) (31)
CYP3A variation, premenopausal estrone levels, and breast cancer risk. (2012) (31)
Linkage analysis for major histocompatibility complex-related genetic susceptibility in familial chronic lymphocytic leukemia. (2000) (30)
CLL family ‘Pedigree 14’ revisited: 1947–2004 (2005) (30)
Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia. (2009) (30)
Impact of atopy on risk of glioma: a Mendelian randomisation study (2018) (30)
Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus. (2010) (30)
Familial risks of acute myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. (2018) (29)
Second primary cancers in patients with acute lymphoblastic, chronic lymphocytic and hairy cell leukaemia (2019) (29)
Comprehensive assessment of variation at the transforming growth factor β type 1 receptor locus and colorectal cancer predisposition (2010) (29)
Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability. (2003) (29)
Gut microflora associated characteristics in first-degree relatives of children with celiac disease (2007) (29)
Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility (2016) (29)
Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression (2016) (29)
Search for inherited susceptibility to radiation-associated meningioma by genomewide SNP linkage disequilibrium mapping (2011) (28)
Genome-Wide Association Studies in Glioma (2018) (28)
Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked coeliac disease susceptibility genes (1999) (28)
Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer (2015) (28)
The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells (2015) (28)
Glioma-related seizures in relation to histopathological subtypes: a report from the glioma international case–control study (2018) (28)
Low-Penetrance Susceptibility Variants in Familial Colorectal Cancer (2010) (28)
Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients (2021) (28)
Analysis of a large multi‐generational family provides insight into the genetics of chronic lymphocytic leukemia (2008) (27)
An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. (2011) (27)
Subclonal TP53 copy number is associated with prognosis in multiple myeloma. (2018) (27)
Association between leptin receptor gene polymorphisms and early‐onset prostate cancer (2003) (27)
MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia. (2011) (27)
The CDH1‐160C>A polymorphism is a risk factor for colorectal cancer (2009) (27)
Genetic predisposition to gastric cancer. (1999) (27)
Duplication of 16q22-->qter confirmed by fluorescence in situ hybridisation and molecular analysis. (1994) (27)
Sex-specific gene and pathway modeling of inherited glioma risk (2017) (27)
Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer. (2016) (27)
Association between polymorphisms of the GPX1 gene and second primary tumours after index squamous cell cancer of the head and neck. (2005) (26)
Colorectal Cancer Mortality in First-Degree Relatives of Early-Onset Colorectal Cancer Cases (2002) (26)
Genome‐wide association study and meta‐analysis in Northern European populations replicate multiple colorectal cancer risk loci (2017) (26)
Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma (2007) (26)
Optimising methods for determining RER status in colorectal cancers. (2000) (26)
Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance (2006) (26)
Influence of obesity-related risk factors in the aetiology of glioma (2018) (26)
Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk (2011) (26)
The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A (2015) (25)
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 (2018) (25)
Comprehensive genetic analysis of seven large families with mismatch repair proficient colorectal cancer (2010) (25)
Chromosomal imbalances in familial chronic lymphocytic leukaemia: a comparative genomic hybridisation analysis (2002) (25)
Clonal lymphocytes in persons without known chronic lymphocytic leukemia (CLL): implications of recent findings in family members of CLL patients. (2004) (25)
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics (2019) (25)
Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population (2018) (25)
MTHFR polymorphisms and risk of chronic lymphocytic leukemia. (2004) (25)
Predicting ultrahigh risk multiple myeloma by molecular profiling: an analysis of newly diagnosed transplant eligible myeloma XI trial patients (2020) (25)
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk (2014) (25)
Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation (2010) (25)
Macrophage Scavenger Receptor 1 999C>T (R293X) Mutation and Risk of Prostate Cancer (2005) (25)
Mutations in Bcl10 are very rare in colorectal cancer (1999) (25)
No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas. (2006) (25)
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology (2018) (25)
Evaluation of xeroderma pigmentosum XPA, XPC, XPD, XPF, XPB, XPG and DDB2 genes in familial early‐onset lung cancer predisposition (2006) (24)
Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia (2017) (24)
Variation in TP63 is Associated with Lung Adenocarcinoma in the UK Population (2011) (24)
A two-phase case–control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22 (2011) (24)
Linkage of recessive Robinow syndrome to a 4 cM interval on chromosome 9q22 (2000) (24)
Genome-wide association studies for detecting cancer susceptibility. (2011) (24)
Somatic PIK3CA Mutations in Sporadic Cerebral Cavernous Malformations. (2021) (24)
Use of family history in a screening clinic for familial ovarian cancer. (1992) (24)
FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma. (2012) (24)
Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients. (2012) (24)
Impact of polymorphic variation at 7p15.3, 3p22.1 and 2p23.3 loci on risk of multiple myeloma (2012) (24)
Mendelian randomization provides support for obesity as a risk factor for meningioma (2019) (23)
Meeting report from the joint IARC–NCI international cancer seminar series: a focus on colorectal cancer (2019) (23)
Relationship between ARLTS1 polymorphisms and risk of chronic lymphocytic leukemia. (2006) (23)
Risk of ovarian cancer and genetic relationship to other cancers in families. (1993) (23)
Mendelian randomisation: A powerful and inexpensive method for identifying and excluding non-genetic risk factors for colorectal cancer (2019) (22)
Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13 (2011) (22)
Common Variation at 1q24.1 (ALDH9A1) Is a Potential Risk Factor for Renal Cancer (2015) (22)
Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci (2011) (22)
Transverse limb deficiency, facial clefting and hypoxic renal damage: an association with treatment of maternal hypertension? (1995) (22)
The Challenges of Genome Analysis in the Health Care Setting (2014) (22)
Genetic predisposition for multiple myeloma (2020) (22)
Genetic variation and risk of chronic lymphocytic leukaemia. (2010) (22)
Genetic epidemiology of differences in low‐density lipoprotein (LDL) cholesterol concentration: Possible involvement of variation at the apolipoprotein B gene locus in LDL kinetics (1990) (21)
Deciphering associations for lung cancer risk through imputation and analysis of 12 316 cases and 16 831 controls (2015) (21)
Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma (2012) (21)
Will polygenic risk scores for cancer ever be clinically useful? (2021) (21)
PhyreRisk: A Dynamic Web Application to Bridge Genomics, Proteomics and 3D Structural Data to Guide Interpretation of Human Genetic Variants (2019) (21)
Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development (2019) (21)
Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer. (2013) (21)
Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11.2 is mediated by a CEBPE promoter polymorphism (2018) (21)
Biochemistry and Clinical Significance of Lipoprotein (a) (1988) (20)
Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium (2015) (20)
Second primary cancers in non‐Hodgkin lymphoma: Bidirectional analyses suggesting role for immune dysfunction (2018) (20)
Apolipoprotein (apo) E genotypes by polymerase chain reaction and allele-specific oligonucleotide probes: no detectable linkage disequilibrium between apo E and apo CII (1989) (20)
Risk of developing chronic lymphocytic leukemia is influenced by HLA-A class I variation (2012) (20)
Analysis of Li-Fraumeni syndrome and Li-Fraumeni-like families for germline mutations in Bcl10. (1999) (20)
Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis (2019) (20)
Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases (2003) (20)
Localisation of the gene for glycogen storage disease type 1c by homozygosity mapping to 11q. (1998) (19)
A genome-wide association study identi fi es risk loci for childhood acute lymphoblastic leukemia at 10 q 26 . 13 and 12 q 23 . 1 (2017) (19)
Plasminogen activator inhibitor variants PAI-1 A15T and PAI-2 S413C influence lung cancer prognosis. (2009) (19)
Copy number evolution and its relationship with patient outcome—an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial (2020) (19)
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia (2010) (19)
Neutral tumor evolution in myeloma is associated with poor prognosis. (2017) (19)
Familial cancer associated with a polymorphism in ARLTS1. (2006) (19)
Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. (2019) (19)
Transcriptome‐wide association study reveals candidate causal genes for lung cancer (2018) (19)
A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma (2012) (18)
Overgrowth syndromes: is dysfunctional PI3-kinase signalling a unifying mechanism? (2003) (18)
Risk estimates for screening adenomatous polyposis coli (1990) (18)
Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma (2015) (18)
Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis (2019) (18)
Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology. (2018) (18)
Meta-analysis and pooled re-analysis of copy number changes in colorectal cancer detected by comparative genomic hybridization. (2006) (18)
Urgent improvements needed to diagnose and manage Lynch syndrome (2017) (18)
LIPOPROTEIN (a) AND CORONARY HEART DISEASE IN FAMILIAL HYPERCHOLESTEROLAEMIA (1988) (18)
Sequence changes in predicted promoter elements of STK11/LKB1 are unlikely to contribute to Peutz-Jeghers syndrome (2005) (17)
Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report (2017) (17)
Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics (2020) (17)
Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. (2001) (17)
Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma. (2019) (17)
Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer (2014) (17)
Protein-altering germline mutations implicate novel genes related to lung cancer development (2020) (17)
Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism (2017) (17)
Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study. (2011) (17)
Case‐control study of familial lung cancer risks in UK women (2005) (17)
IRF4 polymorphism rs872071 and risk of Hodgkin lymphoma (2010) (17)
Allergy and glioma risk: Test of association by genotype (2011) (17)
Age‐specific genome‐wide association study in glioblastoma identifies increased proportion of ‘lower grade glioma’‐like features associated with younger age (2018) (17)
CASP8 D302H and meningioma risk: an analysis of five case-control series. (2009) (17)
Identification of novel Tapasin polymorphisms and linkage disequilibrium to MHC class I alleles (2000) (17)
Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma. (2018) (16)
What are genome-wide association studies telling us about B-cell tumor development? (2010) (16)
The molecular basis of familial chronic lymphocytic leukemia (2009) (16)
Genome-wide association analysis identifies a meningioma risk locus at 11p15.5 (2018) (16)
Germline polymorphisms and survival of lung adenocarcinoma patients: A genome‐wide study in two European patient series (2015) (16)
Epidemiology, genetics and treatment of multiple myeloma and precursor diseases (2021) (16)
Screening and genetic counselling for relatives of patients with breast cancer in a family cancer clinic. (1992) (16)
Gemfibrozil in the Treatment of Resistant Familial Hypercholesterolemia and Type III Hyperlipoproteinaemia (1988) (16)
Candidate gene association studies and risk of Hodgkin lymphoma: a systematic review and meta‐analysis (2017) (16)
GPC5 rs2352028 variant and risk of lung cancer in never smokers. (2010) (16)
TGFBR1 variants TGFBR1*6A and Int7G24A are not associated with an increased familial colorectal cancer risk (2009) (16)
Analysis of familial male breast cancer for germline mutations in CHEK2. (2004) (15)
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides. (2016) (15)
Localisation of merosin-positive congenital muscular dystrophy to chromosome 4p16.3 (2005) (15)
Case-control study of familial lung cancer risks in UK women. (2005) (15)
Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial (2011) (15)
Contribution of Germline Mutations in BRCA 2 , P 16 INK 4 A , P 14 ARF and P 15 to Uveal Melanoma (2003) (15)
Further observations on the Floating-Harbor syndrome. (1994) (15)
Genetic prognostic markers in colorectal cancer. (1997) (14)
EXO 1 Variants Occur Commonly in Normal Population : Evidence against a Role in Hereditary Nonpolyposis Colorectal Cancer 1 (2002) (14)
Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma (2019) (14)
Glutathione S-Transferase M 1 Status and Lung Cancer Risk : A Meta-Analysis (1999) (14)
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families. (2008) (14)
Segregation analysis of colorectal cancer in Northern Ireland. (1995) (14)
Search for multiple myeloma risk factors using Mendelian randomization. (2020) (14)
Meta-Analysis of Genome-Wide Linkage Studies in Celiac Disease (2009) (14)
Rapid diagnosis of familial defective apolipoprotein B-100 by Amplification Refractory Mutation System. (1991) (14)
Mendelian randomisation study of the relationship between vitamin D and risk of glioma (2018) (14)
Birth order pattern in the inheritance of chronic lymphocytic leukaemia and related lymphoproliferative disease (2007) (14)
Risk of second primary cancer following myeloid neoplasia and risk of myeloid neoplasia as second primary cancer: a nationwide, observational follow up study in Sweden. (2018) (13)
Leveraging Ethnic Group Incidence Variation to Investigate Genetic Susceptibility to Glioma: A Novel Candidate SNP Approach (2012) (13)
Identification of recurrent noncoding mutations in B-cell lymphoma using capture Hi-C. (2019) (13)
Homozygosity at chromosome 8qter in individuals affected by mal de Meleda (Meleda disease) originating from the island of Meleda (2001) (13)
Architecture of Inherited Susceptibility to Colorectal Cancer: A Voyage of Discovery (2014) (13)
Variants in the ATM-BRCA 2-CHEK 2 axis predispose to chronic lymphocytic leukemia (2006) (13)
Familial breast cancer: who is at risk (1997) (13)
Genome-wide homozygosity signature and risk of Hodgkin lymphoma (2015) (13)
DNA-repair gene variants are associated with glioblastoma survival (2012) (13)
Common genetic variation contributes significantly to the risk of developing chronic lymphocytic leukemia (2013) (13)
Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma (2019) (13)
Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patients. (2007) (13)
Functional variants in DCAF4 associated with lung cancer risk in European populations (2017) (13)
Whole-Genome Amplification by Improved Primer Extension Preamplification PCR (I-PEP-PCR). (2008) (13)
A genome-wide association study identifies susceptibility loci for primary central nervous system lymphoma at 6p25.3 and 3p22.1: a LOC network study. (2019) (13)
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance (2019) (12)
The carrier clinic: an evaluation of a novel clinic dedicated to the follow-up of BRCA1 and BRCA2 carriers—implications for oncogenetics practice (2010) (12)
Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers (2021) (12)
Role of MC1R variants in uveal melanoma (2003) (12)
Searching for the missing heritability of complex diseases (2011) (12)
Case–control, kin-cohort and meta-analyses provide no support for STK15 F31I as a low penetrance colorectal cancer allele (2006) (12)
Candidate gene association studies and risk of chronic lymphocytic leukemia: a systematic review and meta-analysis (2014) (12)
Inherited susceptibility to CLL. (2013) (12)
Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes (2019) (12)
Erratum: Evidence for a colorectal cancer susceptibility locus on chromosome 3q21 - q24 from a high-density SNP genome-wide linkage scan (Human Molecular Genetics (2006) vol. 15 (2903-2910) 10.1093/hmg/ddl231) (2006) (12)
A practical guide to constructing and using tissue microarrays. (2011) (12)
GenomePlex Whole-Genome Amplification. (2008) (12)
Meeting report from the joint IARC-NCI international cancer seminar series: a focus on colorectal cancer. (2019) (12)
Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study (2013) (12)
Polymorphisms in PTGS1, PTGS2 and IL‐10 do not influence colorectal adenoma recurrence in the context of a randomized aspirin intervention trial (2007) (12)
Aspirin, NSAIDs, and Glioma Risk: Original Data from the Glioma International Case–Control Study and a Meta-analysis (2018) (12)
Re: Reporting recommendations for tumor marker prognostic studies (REMARK). (2005) (12)
Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis (2015) (11)
A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. (2011) (11)
Genetic factors influencing the risk of multiple myeloma bone disease (2015) (11)
Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. (2015) (11)
Familial predisposition to both male and female germ cell tumours? (1996) (11)
Search for rare protein altering variants influencing susceptibility to multiple myeloma (2017) (11)
Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2021) (11)
Apparent Mendelian inheritance of breast and colorectal cancer: chance, genetic heterogeneity or a new gene? (2004) (11)
Association of Genetic Variants at 8 q 24 with Breast Cancer Risk (2008) (11)
Inherited pericentric inversion (X)(p11.4q11.2) associated with delayed puberty and obesity in two brothers (2005) (11)
A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival (2015) (10)
Germline mutations in RAD51, RAD51AP1, RAD51B, RAD51C,RAD51D, RAD52 and RAD54L do not contribute to familial chronic lymphocytic leukemia (2008) (10)
Allelic imbalance in colorectal cancer at the CRAC1 locus in early-onset colorectal cancer. (2003) (10)
Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer (2017) (10)
Re: MLH1 93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. (2007) (10)
Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study (2021) (10)
Co-Morbidity between Early-Onset Leukemia and Type 1 Diabetes – Suggestive of a Shared Viral Etiology? (2012) (10)
Plasma fibrinogen levels and fibrinogen genotype in non-insulin dependent diabetics. (1992) (10)
Glutathione S-Transferase M1 Status and Lung Cancer Risk (1999) (10)
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer (2003) (10)
Increased sex concordance of sibling pairs with chronic lymphocytic leukemia (2004) (10)
Pathway‐analysis of published genome‐wide association studies of lung cancer: A potential role for the CYP4F3 locus (2017) (10)
Polymorphisms of the apolipoprotein B and E genes and their possible roles in familial and non-familial combined hyperlipidaemia. (1991) (10)
Variation in the apolipoprotein B gene and development of type 2 diabetes mellitus. (1991) (10)
Penetrance of mutations in the familial Wilms tumor gene FWT1. (2000) (10)
Clinical geneticists' attitudes and practice towards testing for breast cancer susceptibility genes (2000) (10)
Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia (2020) (10)
Capture Hi‐C Library Generation and Analysis to Detect Chromatin Interactions (2018) (10)
Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer (2019) (10)
Instability of CAG-trinucleotide Repeats in Chronic Lymphocytic Leukemia (2002) (10)
Quantifying and mitigating the impact of the COVID-19 pandemic on outcomes in colorectal cancer (2020) (10)
Characteristic facies in type B brachydactyly? (1994) (10)
CanVar: A resource for sharing germline variation in cancer patients (2016) (10)
A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk (2009) (10)
Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach (2017) (9)
Common Susceptibility Loci for Male Breast Cancer (2020) (9)
Identification of miRSNPs associated with the risk of multiple myeloma (2017) (9)
Polygenic susceptibility to testicular cancer: implications for personalised health care (2015) (9)
Relationship Between Thymidylate Synthase (TS) Genotype and TS Expression: A Tissue Microarray Analysis of Colorectal Cancers (2005) (9)
Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs (2017) (9)
Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients (2019) (9)
Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes (2016) (9)
Prediction of colorectal cancer risk based on profiling with common genetic variants (2019) (9)
Lack of a relationship between the common 18q24 variant rs12953717 and risk of chronic lymphocytic leukemia (2008) (9)
Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. (2014) (9)
Ataxia telangiectasia gene mutations and chronic lymphocytic leukaemia (1999) (9)
Bcl10 in chronic lymphocytic leukaemia and T‐cell prolymphocytic leukaemia (1999) (9)
Common variation at 6 p 21 . 31 ( BAK 1 ) influences the risk of chronic lymphocytic leukemia * (2012) (9)
Low-penetrance susceptibility to hematological malignancy. (2010) (9)
Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer (2018) (9)
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation (2022) (9)
The association of rs1051730 genotype on adherence to and consumption of prescribed nicotine replacement therapy dose during a smoking cessation attempt (2015) (9)
Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium (2017) (9)
Second cancer risk following Hodgkin lymphoma (2017) (9)
Polygenic susceptibility to testicular cancer: implications for personalised health care (2016) (8)
Partitioned glioma heritability shows subtype-specific enrichment in immune cells. (2021) (8)
Erratum: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups (2017) (8)
Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia (2015) (8)
Correlation in ages at death from familial ovarian cancer among sisters. (1992) (8)
Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study (2020) (8)
Combined linkage and association analysis of classical Hodgkin lymphoma (2018) (8)
Dominantly inherited cutaneous small-vessel lymphocytic vasculitis maps to chromosome 6q26–q27 (2005) (8)
Second primary cancers in non‐Hodgkin lymphoma: Family history and survival (2020) (8)
Exonic STK 11 deletions are not a rare cause of Peutz-Jeghers syndrome (2006) (8)
The TERT variant rs 2736100 is associated with colorectal cancer risk (2015) (8)
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (2022) (8)
Correspondence: SEMA4A variation and risk of colorectal cancer (2016) (8)
Childhood acute lymphoblastic leukemia-associated risk-loci IKZF1, ARID5B and CEBPE and risk of pediatric non-Hodgkin lymphoma: a report from the Berlin–Frankfurt–Münster Study Group (2015) (8)
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome (2022) (8)
The influence of pregnancy on the development of autoimmunity in chronic lymphocytic leukemia (2006) (8)
MyelomA Genetics International Consortium (2012) (8)
Partitioned glioma heritability shows subtype-specific enrichment in immune cells. (2021) (8)
An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics (2020) (7)
Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk—A re‐analysis of eight GWASs (2017) (7)
Cancer family syndrome associated with multiple malignant melanomas and a malignant fibrous histiocytoma (1992) (7)
Analysis of DNA repair gene polymorphisms and survival in low-grade and anaplastic gliomas (2011) (7)
Prioritizing Rare Variants with Conditional Likelihood Ratios (2015) (7)
A Novel Approach to Exploring Potential Interactions among Single-Nucleotide Polymorphisms of Inflammation Genes in Gliomagenesis: An Exploratory Case-Only Study (2011) (7)
Impact of mitochondrial DNA mutations in multiple myeloma (2020) (7)
Bidirectional Mendelian randomisation analysis of the relationship between circulating vitamin D concentration and colorectal cancer risk (2021) (7)
A form of autosomal dominant spondyloepiphyseal dysplasia is caused by a glycine to alanine substitution in the COL2A1 gene (2006) (7)
Abstract 2931: Inherited variation at chromosome 12p13.33 includingRAD52influences squamous cell lung carcinoma risk (2012) (7)
Microcephaly, focal segmental glomerulonephritis and marfanoid habitus in two sibs. (1992) (7)
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease. (2002) (7)
Pseudoautosomal linkage in chronic lymphocytic leukaemia (2000) (7)
Lack of a relationship between the common 8q24 variant rs6983267 and risk of chronic lymphocytic leukemia (2008) (7)
Spatiotemporal Analysis of Intraclonal Heterogeneity in Multiple Myeloma: Unravelling the Impact of Treatment and the Propagating Capacity of Subclones Using Whole Exome Sequencing (2015) (7)
Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts (2017) (7)
Detection of apolipoprotein E polymorphisms using PCR/ASO probes and Southern transfer: application for routine use. (1990) (7)
The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1plus) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment (2014) (6)
No Breast Cancer Association for Transforming Growth Factor-β Pathway Colorectal Cancer Single Nucleotide Polymorphisms (2009) (6)
CHEK2*1100delC and risk of chronic lymphocytic leukemia (2006) (6)
Familial colorectal cancer and genetic testic (1998) (6)
Mismatch repair, minichromosome maintenance complex component 2, cyclin A, and transforming growth factor β receptor type II as prognostic factors for colorectal cancer: results of a 10-year prospective study using tissue microarray analysis. (2011) (6)
Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia (2021) (6)
Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants. (2019) (6)
A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data (2012) (6)
The P 2 X 7 Receptor Gene A 1513 C Polymorphism Does Not Contribute to Risk of Familial or Sporadic Chronic Lymphocytic Leukemia (2004) (6)
Cerebral infarction due to moyamoya disease in an 18 year old female. (1993) (6)
Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls. (2016) (6)
Alcohol consumption, DNA methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis (2022) (6)
A meta-analysis of microsatellite instability and colorectal cancer prognosis. (2004) (5)
Multiple HLA class I and II associations in classical Hodgkin lymphoma and EBV status defined subgroups. (2011) (5)
A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk (2011) (5)
Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals (2021) (5)
Interobserver agreement in grading of colorectal cancers – findings from a nationwide web‐based survey of histopathologists (2008) (5)
Germline mutations in Dok1 do not predispose to chronic lymphocytic leukemia. (2005) (5)
Integrating genome-wide polygenic risk scores and non-genetic risk to predict colorectal cancer diagnosis using UK Biobank data: population based cohort study (2022) (5)
Mendelian randomisation analysis provides no evidence for a relationship between adult height and testicular cancer risk (2017) (5)
Polymorphic Variation and Risk of Colorectal Cancer (2010) (5)
Inherited Predisposition to Chronic Lymphocytic Leukemia (2004) (5)
Pulmonary Masses Presenting 11 Years after Abdominal Surgery (2004) (5)
Is EXO1 a colon cancer predisposition gene? (2001) (5)
Pathway Analysis of Renal Cell Carcinoma Genome-Wide Association Studies Identifies Novel Associations (2020) (5)
Colorectal cancer screening. (1999) (5)
Role of monoamine-oxidase-A-gene variation in the development of glioblastoma in males: a case control study (2019) (5)
Runs of homozygosity and testicular cancer risk (2019) (5)
A genome-wide analysis of loss of heterozygosity and chromosomal copy number variation in Proteus syndrome using high-density SNP microarrays (2010) (5)
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features (2022) (4)
Correction: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer (2016) (4)
The 9 p 21 . 3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN 2 A (2015) (4)
Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium (2014) (4)
Germline mutations in TGM2 do not contribute to coeliac disease susceptibility in the Swedish population (2001) (4)
Germline loss-of-function variants in the base-excision repair gene MBD4 cause a Mendelian recessive syndrome of adenomatous colorectal polyposis and acute myeloid leukaemia (2021) (4)
Publisher Correction: Shared heritability and functional enrichment across six solid cancers (2019) (4)
Relationship between genetically determined telomere length and glioma risk (2021) (4)
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH 2 B 3 and TSHZ 1 (2015) (4)
Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis (2021) (4)
Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (2017) (4)
Single Nucleotide Polymorphisms and Cancer Susceptibility (2017) (4)
Identification of the cystic fibrosis gene. (1990) (4)
Prediction of genetic risks from segregation analyses of morbid risks. (1994) (4)
Mutations in the candidate tumour suppressor gene FLJ12973 on chromosome 15q15 are rare in colorectal cancer. (2003) (4)
Genetic predisposition to chronic lymphocytic leukemia (2019) (4)
Whole-Genome Amplification by Adaptor-Ligation PCR of Randomly Sheared Genomic DNA (PRSG). (2008) (4)
Concurrent deIetions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 (IKZF1plus) confer a very poor prognosis in pediatric acute lymphoblastic leukemia (2014) (4)
Genetic predisposition to non-medullary thyroid cancer. (1998) (4)
Germline variants at SOHLH2 influence multiple myeloma risk (2021) (4)
Search for AL amyloidosis risk factors using Mendelian randomization. (2021) (4)
Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (4)
Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer (2015) (4)
CYP 3 A Variation , Premenopausal Estrone Levels , and Breast Cancer Risk (2012) (4)
Taurodontism and disproportionate short stature. (1994) (3)
Loci other than 21q22.12 (RUNX1) and 16q21–23.2 cause familial AML (2005) (3)
The Novel Protein HSF1 Stress Pathway Inhibitor Bisamide CCT361814 Demonstrates Pre-Clinical Anti-Tumor Activity in Myeloma (2017) (3)
Lung adenocarcinoma promotion by air pollutants (2023) (3)
Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes (2021) (3)
Functional dissection of inherited non-coding variation influencing multiple myeloma risk (2022) (3)
Genome‐wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer (2021) (3)
Risk of Childhood Acute Lymphoblastic Leukemia: Identification of Inherited Susceptibility (2013) (3)
A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients. (2021) (3)
TGFBR 1 variants TGFBR 1 * 6 A and Int 7 G 24 A are not associated with an increased familial colorectal cancer risk (2010) (3)
Genetic variation in CXCR 4 and risk of chronic lymphocytic leukemia (2009) (3)
Genetic lung cancer predisposition study (GELCAPS) (2000) (3)
Fluorescent BAT-25 and BAT-26 analysis of T cell prolymphocytic leukaemia (1999) (3)
A proposed BAT-26 germline polymorphism. (2000) (3)
Medical and psychological perspectives on breast cancer screening: A comment on Pitts, McMaster and Wilson (1991) (3)
Polygenic risk scores to stratify cancer screening should predict mortality not incidence (2022) (3)
Identifying Ultra-High Risk Myeloma By Integrated Molecular Genetic and Gene Expression Profiling (2016) (3)
Extended Intensified Post-ASCT Consolidation with Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (Dara-VRd) for Ultra-High Risk (UHiR) Newly Diagnosed Myeloma (NDMM) and Primary Plasma Cell Leukemia (pPCL): The UK Optimum/Muknine Trial (2022) (3)
A genomic approach to estimating the heritability of Hodgkin lymphoma (2015) (2)
Effect of delays in the UK two-week wait cancer referral pathway during the COVID-19 pandemic on cancer survival: a modelling study (2020) (2)
Duplication of 16 q 22-+ qter confirmed by fluorescence in situ hybridisation and molecular analysis (2)
Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2022) (2)
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study (2022) (2)
A gene locus for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 17p1-q3 (1997) (2)
Sex-specific genome-wide association study in glioma identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 (2017) (2)
Constitutional mutation in CDKN 2 A is associated with long term survivorship in multiple myeloma : a case report (2017) (2)
Apolipoprotein (APO) B DNA polymorphism associated with differences in LDL metabolism (1987) (2)
Genetic Variation in ABCC4 and CFTR and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia (2021) (2)
Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics (2017) (2)
False-Negative-Rate Based Approach for Selecting Top Single-Nucleotide Polymorphisms in the First Stage of a Two-Stage Genome-Wide Association Study. (2011) (2)
A novel DNA repair disorder with thrombocytopenia, nephrosis and features overlapping Cockayne syndrome (2009) (2)
Whole-Genome Amplification by Single-Cell Comparative Genomic Hybridization PCR (SCOMP). (2008) (2)
Association of atrial-ventricular septal defect, blepharophimosis, anal and radial defects in sibs: a new syndrome? (1994) (2)
Algorithmic considerations when analysing capture Hi-C data (2020) (2)
MBL and MoBL – Response to Ziegler‐Heitbrock (2005) (2)
Etiology and Epidemiology of CLL (2013) (1)
Nonmedullary Thyroid Cancer and the Role of the Geneticist (2006) (1)
A genome-wide association study of tag SNPs identify five novel colorectal cancer susceptibility loci (2008) (1)
OS06.1 Genome-wide association study reveals specific differences in genetic susceptibility to glioblastoma and non-glioblastoma (2017) (1)
International cancer seminars:a focus on colorectal cancer (2019) (1)
MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukaemia MHC variation (2011) (1)
The meaning of risk: Women's perceptions of the genetic risk of breast and ovarian cancer following BRCA1/2 mutation searching (2002) (1)
Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2019) (1)
Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases (2022) (1)
Publisher Correction: Cancer genetics, precision prevention and a call to action (2018) (1)
Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma (2019) (1)
Comment on: MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. Authors' reply (2007) (1)
Aspirin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), and Glioma Risk: Original Data from the Glioma International Case-Control Study and a Meta-Analysis (2018) (1)
Association between SNP-genotype and chronic lymphocytic leukemia outcome in a randomized chemotherapy trial (2011) (1)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
A method for determining familial cancer risks in clinical practice. (1996) (1)
Multicentre Genome Wide Association Study Identifies Risk Alleles for Progressive Chronic Lymphocytic Leukaemia (2019) (1)
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2018) (1)
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 (2018) (1)
Integrating genome-wide polygenic risk scores and non-genetic risk factors to develop and validate risk prediction models for colorectal cancer (2021) (1)
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
Multiple mechanisms can disrupt oncogenic pathways in multiple myeloma (2018) (1)
Correction: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups (2019) (1)
Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (2022) (1)
Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes (2016) (1)
rs2072135, a low‐penetrance variant for chronic lymphocytic leukaemia? (2013) (1)
Erratum to: Survey of familial glioma and role of germline p16/p14 and p53 mutation (2010) (1)
Abstract #LB-139: A comprehensive genome-wide association study of lung cancer (2009) (1)
Special section editorial (2014) (1)
Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma" [Eur Urol 2017;72:747-54]. (2018) (1)
Approaching a Scienti fi c Consensus on the Association between Allergies and Glioma Risk : A Report from the Glioma International Case-Control Study (2016) (1)
Presentation of primary small bowel malignancy in the united kingdom — a prospective national survey (2000) (1)
Leveraging Human Genetics to Guide Cancer Drug Development. (2018) (1)
Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank (2021) (1)
Optimizing the value of lenalidomide maintenance by genetic profiling - an analysis of 556 Myeloma XI trial patients. (2022) (1)
A prospective blinded study of microsatellite instability (MSI) as a marker of overall survival (OS) in the adjuvant treatment of colorectal cancer (CRC) patients (2005) (1)
Algorithmic considerations when analysing capture Hi-C data. (2020) (1)
Realistic expectations are key to realising the benefits of polygenic scores (2023) (1)
A common low penetrance risk allele for chronic lymphocytic leukaemia in the 3’ UTR of IRF4/MUM1 predicts prognosis independent of 1gVH status. (2010) (1)
Abstract 2986: Meta-analysis of whole exome sequencing data reveals the mutational spectrum of testicular germ cell tumors (2015) (1)
DNA Methylation Profiling of Myeloma Trial Patients Reveals Specific Epigenetic Changes Associated with Outcome (2016) (1)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (1)
FAMILIAL DEFECTIVE APOLIPOPROTEIN B-100 - DETECTION AND CLINICAL CHARACTERISTICS (1990) (1)
GlutathioneS-Transferase M1 Status and Lung Cancer Risk: A Meta-Analysis (1999) (1)
Mutational Analysis of CD28 in Coeliac Disease (2002) (1)
lymphocytic leukemia Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic (2013) (1)
Nucleotide excision repair polymorphisms modulate overall lung cancer survival and responsiveness to platinum based chemotherapy agents. (2006) (1)
THE INVOLVEMENT OF APOLIPOPROTEIN B GENE VARIANTS IN THE DETERMINATION OF SERUM CHOLESTEROL LEVELS (1987) (1)
RISK OF CANCER IN RELATIVES OF PATIENTS WITH CUTANEOUS MELANOMA (1993) (1)
ATOPIC CONDITIONS, ANTIHISTAMINE USE, AND GLIOMA RISK : PRELIMINARY RESULTS FROM THE GLIOMA INTERNATIONAL CASE-CONTROL STUDY (2013) (1)
Analysis of rare disruptive germline mutations in 2,135 enriched BRCA-negative breast cancers excludes additional high-impact susceptibility genes. (2022) (1)
Comment on: Reporting recommendations for tumor marker prognostic studies (REMARK). Authors' reply (2005) (1)
A comparison of the effect of genetic variation in the genes for apo B & apo E in the determination of normal plasma lipid lipoprotein concentrations (1987) (1)
Elongin C (ELOC/TCEB1)-associated von Hippel–Lindau disease (2022) (1)
Congenital hypertrophy of retinal pigment epithelium and risk estimation in adenomatous polyposis coli (1990) (1)
Use of family history in a screening clinic for familial ovarian cancer (1993) (1)
Microsatellite instability indicative of defects in the major mismatch repair genes is rare in patients with B-cell chronic lymphocytic leukemia: Evaluation with disease stage and family history (2007) (1)
Abstract 4349: Identifying causal risk factors of metabolic syndrome for renal cell carcinoma. A Mendelian randomization approach (2016) (1)
OVARIAN CANCER FAMILY AND PROPHYLACTIC CHOICES. AUTHOR'S REPLY (1992) (0)
Abstract 64: Fine mapping and in silico analysis of the 8q24.21 region for glioma identifies a low-frequency risk variant insight into etiological basis of glioma. (2012) (0)
Breast cancer: who is at risk? (1997) (0)
Publisher Correction: Mendelian randomisation study of the relationship between vitamin D and risk of glioma (2019) (0)
The association between genetically elevated polyunsaturated fatty acids and risk of cancer (2023) (0)
Abstract 4597: A novel variant in DNA repair gene GTF2H4 is associated with lung cancer risk: A reanalysis of GWAS datasets from the TRICL consortium (2015) (0)
The clinical utility of polygenic risk scores for chronic lymphocytic leukemia (2021) (0)
Brief report Common variation at 6p21.31 ( BAK1 ) inﬂuences the risk of chronic lymphocytic leukemia (2012) (0)
Author response: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation (2021) (0)
SEMA 4 A variation and risk of colorectal cancer (2016) (0)
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (2023) (0)
Medullary and non-medullary thyroid cancer in a family (2004) (0)
Cumulative impact of 10 common genetic variants on colorectal cancer risk in 42,333 individuals from eight populations (2013) (0)
Physical activity reduces colorectal cancer risk independent of BMI—A two-sample Mendelian randomisation study (2019) (0)
Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer (2018) (0)
Correction: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation (2022) (0)
Publisher Correction: Cancer genetics, precision prevention and a call to action (2018) (0)
Contents Vol. 68, 2009 (2009) (0)
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2010) (0)
Abstract P3-08-04: Impact of CYP3A variation on estrone levels and breast cancer risk (2012) (0)
Association analyses identify 31 new risk loci for colorectal cancer susceptibility (2019) (0)
Reference bias in the Illumina Isaac aligner (2020) (0)
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group (2023) (0)
Genetics and heart disease (1987) (0)
Exploiting gene dependency to inform drug development for multiple myeloma (2022) (0)
P-087 Search for susceptibility alleles to lung cancer by screeningfamilial cases for constitutional mutations in the Xeroderma Pigmentosum Complementation genes (2005) (0)
Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium (2017) (0)
Protein-altering germline mutations implicate novel genes related to lung cancer development (2020) (0)
Explorer A new GWAS and meta-analysis with 1000 Genomes imputation identifies novel risk variants for colorectal cancer (2017) (0)
Publisher Correction: Mendelian randomisation study of the relationship between vitamin D and risk of glioma (2019) (0)
Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions. (2023) (0)
Will gene testing cut risk of familial colorectal cancer? (1998) (0)
LYMPHOID NEOPLASIA Germ line mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia (2016) (0)
OP03. Genomics England’s 100,000 Genome Project: Where do brain tumours fit in? (2017) (0)
No association between the GSTM1, GSTT1, and GSTP1 gene polymorphisms, squamous cell cancer of the head and neck and second primary tumours (2000) (0)
Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls (2023) (0)
Subject Index Vol. 68, 2009 (2009) (0)
Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6 (2022) (0)
Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia (2021) (0)
Exploring the complex relationship between gut microbiota and risk of colorectal neoplasia using bidirectional Mendelian Randomization analysis. (2023) (0)
Genetics of Lung Cancer: Current Thinking on Genetic Predisposition to the Disease and Response to Treatment (2006) (0)
Author Correction: Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2 (2018) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Etiology and Epidemiology of Chronic Lymphocytic Leukemia (2018) (0)
Neutral Tumor Evolution in Myeloma is Associated With Poor Response to Therapy (2017) (0)
Risk of second primary cancer following myeloid neoplasia and risk of myeloid neoplasia as second primary cancer a nationwide follow-up study (2018) (0)
Clinical Cancer esearch ing , Diagnosis , Prognosis etic Risk Profiles Identify Different R ecular Etiologies for Glioma (2010) (0)
Common variation at 6 p 21 . 2 ( CDKN 1 A ) , 11 q 13 . 4 ( POLD 3 ) and Xp 22 . 2 influences colorectal cancer risk (2013) (0)
Deletion of CDKN2C drives the prognostic impact of deletion 1P in multiple myeloma (2016) (0)
STRATEGIES FOR DETECTION OF SINGLE BASE CHANGES IN SUBJECTS HETEROZYGOUS FOR ALLELES OF THE APOLIPOPROTEIN-B GENE (1990) (0)
Expression Quantitative Trait Loci Reveal Regulatory Regions Important In The Pathogenesis of Multiple Myeloma (2013) (0)
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival (2023) (0)
Distinct GeneticandEpigenetic Changes inMedullaryBreastCancer (2003) (0)
Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions (2022) (0)
For Review Only Cockayne-like syndrome with thrombocytopenia and nephrotic syndrome. (2008) (0)
DYNAMIC EVOLUTION OF COPY NUMBER ABERRATIONS ACCOMPANIES DISEASE RELAPSE IN MULTIPLE MYELOMA (2016) (0)
Clinical expert letter:: Improving the identification and management of Lynch syndrome in the UK (2017) (0)
Characterisation of Long-Term Responders to First-Line Myeloma Therapy - Results from the UK Myeloma IX and XI Trials (2018) (0)
Molecular Subgroups of Hyperdiploidy and Their Prognostic Relevance - an Analysis of 1,036 Myeloma Trial Patients (2015) (0)
Abstract 1302: Genome-wide association study of glioma reveals specific differences in genetic susceptibility to glioblastoma and non-glioblastoma (2017) (0)
Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (0)
Abstract 3864: Low-penetrance variants underlying familial colorectal cancer (2010) (0)
The genomic landscape of familial glioma (2023) (0)
DEMOGRAPHICS AND LIFESTYLE FACTORS IN GLIOMA RISK : A REPORT FROM THE GLIOMA INTERNATIONAL CASE-CONTROL STUDY (2016) (0)
Erratum: Survey of familial glioma and role of germline p16 INK4A/p14ARF and p53 mutation (Familial Cancer DOI: 10.1007/s10689-010-9346-5) (2010) (0)
Lack of an Association between the TGFBR 1 * 6 AVariant and Colorectal Cancer (2007) (0)
Juvenile polyposis lesions show clonal loss of SMAD4 in epithelial as well as stromal compartments, endorsing the "gatekeeper" not the "landscaper" hypothesis [Abstract] (2000) (0)
David N. Cooper (ed) The molecular genetics of lung cancer (2005). Springer, ISBN 3-540-22985-X, hardcover, €106.99 (2005) (0)
Edinburgh Research Explorer Germline Variants and Advanced Colorectal Adenomas (2017) (0)
Influence of obesity-related risk factors in the aetiology of glioma (2018) (0)
Specific Identification of High Risk Disease Using Molecular Profiling By Mymap (Myeloma MLPA and translocation PCR) of 1,036 Cases (2015) (0)
Variation in the apo b genotype detected with the Xbai restriction fragment length polymorphism (RFLP) influences the kinetics of LDL in normal individuals (1987) (0)
Cancer genetics, precision prevention and a call to action (2018) (0)
Authors and Disclosures (2010) (0)
Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma (2020) (0)
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2017) (0)
GENOME-WIDE ASSOCIATION STUDY OF HODGKIN LYMPHOMA IDENTIFIES HISTOLOGY-SPECIFIC ASSOCIATIONS AND TRANSCRIPTIONAL REGULATORS OF DISEASE SUSCEPTIBILITY (2017) (0)
Null Results in Brief No Breast Cancer Association for Transforming Growth Factor- β Pathway Colorectal Cancer Single Nucleotide Polymorphisms (2009) (0)
B-lymphocyte expansion Inherited predisposition to CLL is detectable as sub-clinical monoclonal (2013) (0)
Abstract 1194: Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions (2020) (0)
PF355 INTEGRATION OF GENOMIC AND EPIGENOMIC DATA REFINES THE REGULATORY MECHANISMS AND BIOLOGICAL SIGNIFICANCE OF CHRONIC LYMPHOCYTIC LEUKEMIA RISK LOCI (2019) (0)
Apo B Gene Variants are Involved in Determining Serum Cholesterol Levels: Towards Identifying these Variants (1989) (0)
Erratum to: Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation (2010) (0)
Molecular pathology of solid tumours: translating research into clinical practice. Introduction and overview (2001) (0)
Abstract 4173: Previously identified common glioma risk SNPs are associated with familial glioma (2019) (0)
rs10795668 located at 10p14 is associated with colorectal cancer risk in Han Chinese (2009) (0)
SCREENING FOR THE APO B(ARG3500-]GLN) MUTATION (1989) (0)
Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes (2019) (0)
Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients (2019) (0)
Syndrome of the month Peutz-Jeghers syndrome (2004) (0)
From linkage to genes : positional cloning. (2000) (0)
HNPCC - Where does the buck stop? (2004) (0)
Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand‐foot syndrome (2022) (0)
Disease Characterisation & Identification of a Novel Gene Locus for Arrhythmogenic Right Ventricular Cardiomyopathy (1997) (0)
Abstract 889: An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for theXRCC4SNPs (2011) (0)
Np 63 α and YB-1 functional interaction regulates proliferation and survival of normal and transformed keratinocytes (2013) (0)
Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank (2021) (0)
Ovarian cancer family and prophylactic choices. (1992) (0)
Identification of germline polymorphisms associated with clinical and toxicity phenotypes in childhood acute lymphoblastic leukemia (2013) (0)
Genetic epidemiology of colorectal, breast and ovarian cancer: Use in clinical practice (1993) (0)
Stage 2 Genome-Wide Association Study of Candidate Low Penetrance Genes Implicated in Breast Cancer Risk (2009) (0)
Pressntation of primary small bowel malignancy in the UK-a prospective national survey over 24 months (1998–2000) (2001) (0)
Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk (2022) (0)
Cross-cancer cross-tissue Transcriptome-wide Association Study (TWAS) of 11 cancers identifies 56 novel genes (2020) (0)
Genomewide Linkage Analysis of Chronic Lymphocytic Leukemia by Use of a High-Density Single Nucleotide Polymorphism Assay Containing 11,555 Markers. (2004) (0)
Abstract 3446: Aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of glioma: Results from the Glioma International Case Control Study (2016) (0)
43rd European Mathematical Genetics Meeting (EMGM) 2015. April 16-17, 2015, Brest, France: Abstracts (2015) (0)
Abstract 407: Targeted Hi-C and integrative analyses reveal functionality of colorectal cancer risk loci (2014) (0)
Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia (2019) (0)
GENE-23. PREVIOUSLY IDENTIFIED COMMON GLIOMA RISK SNPs ARE ASSOCIATED WITH FAMILIAL GLIOMA (2018) (0)
Identi fi cation of susceptibility pathways for the role of chromosome 15 q 25 . 1 in modifying lung cancer risk (2018) (0)
Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (2019) (0)
Abstract 1315: Estimating sex-specific effects of genetic loci associated with glioma risk (2017) (0)
Abstract 4723: Common low penetrance allelic variants for chronic lymphocytic leukemia identified in a genome-wide association study also predict outcome (2010) (0)
Edinburgh Research Explorer SEMA4A variation and risk of colorectal cancer (2018) (0)
Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls (2023) (0)
A Common Genetic Variant in the 3′UTR of IRF4/MUM1 Associates with Risk of Disease and Poor Prognosis in Chronic Lymphocytic Leukaemia. (2008) (0)
Integrating Molecular Genetic and Gene Expression Profiling Allows Stratification of Ultra-High Risk Myeloma (2017) (0)
Fine Mapping of Colorectal Cancer Low Penetrance Susceptibility Loci (2009) (0)
Cerebral infarction duetomoyamoya disease inan 18year oldfemale (1993) (0)
A prospective study confirms mismatch repair status predicts outcome in colorectal cancer (2006) (0)
Erratum: COGENT (COlorectal cancer GENeTics): An international consortium to study the role of polymorphic variation on the risk of colorectal cancer (British Journal of Cancer 102 (447-454) DOI: 10.1038/sj.bjc.6605338)) (2010) (0)
Cardiovascular Risk Factors: Heredity and Gender (1993) (0)
Studies of inherited predisposition to cancer (2012) (0)
Genome-Wide Association Study (GWAS) of High-Risk Minimal Residual Disease and Relapse in B-Cell Acute Lymphoblastic Leukemia on Trial AIEOP-BFM ALL 2000 (2017) (0)
Brief report Veriﬁcation of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood (2010) (0)
Genetic predisposition to mosaic Y chromosome loss in blood (2019) (0)
Correcting reference bias from the Illumina Isaac aligner enables analysis of cancer genomes (2019) (0)
Edinburgh Research Explorer Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer (2018) (0)
Peutz-Jeghers syndrome deletions are not a rare cause of STK11 Exonic (2006) (0)
Germline variation in RASAL2 may predict survival in patients with RAS‐activated colorectal cancer (2023) (0)
Chromosome 7p11.2(EGFR) and 7q36.1(XRCC2) variants influence glioma risk (2011) (0)
Abstract 1844: No evidence for genetic factor increasing renal cell cancer risk in Hereditary Leiomyomatosis and Renal Cell Cancer syndrome (2010) (0)
Familial chronic lymphocytic leukemia (2008) (0)
Genotyping methodologies (2001) (0)
MP09-17 PREDICTING INCIDENCE VERSUS MORTALITY FOR CANCERS ASSOCIATED WITH OVERDIAGNOSIS: AN OVERLOOKED ISSUE FOR POLYGENIC RISK SCORES AND CANCER SCREENING (2022) (0)
P-98 Establishment of a DNA resource through the GELCAPS consortium to study low penetrance susceptibility alleles for lung cancer (2003) (0)
MBL and MoBL - Response (2005) (0)
Abstract 776: Utilising genetic susceptibility and big data to inform novel cancer therapies (2018) (0)
Genomic landscape of platinum resistant and sensitive testicular cancers (2020) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Author Correction: Germline variants at SOHLH2 influence multiple myeloma risk (2021) (0)
Identi fi cation of recurrent noncoding mutations in B-cell lymphoma using capture HiC (2018) (0)
(The British Prostate Group Spring Meeting, 16–17 March 2000, The Swallow Royal Hotel, Bristol) (2000) (0)
Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk (2022) (0)
Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma (2012) (0)
T2029 Whole-Genome Association Scan (Wgas) for Colorectal Cancer: Replicated SNPs in Samples from the Spanish Epicolon Project (2008) (0)
through analysis of IgVH gene usage and mutation status in familial Insight into the pathogenesis of chronic lymphocytic leukemia (CLL) (2013) (0)
Marfan syndrome. (1990) (0)
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk (2018) (0)
Imputation as a method to fine map cancer susceptibility loci (2012) (0)
Genetic variants in EGF, EGFR, ERBB2, LRIG2, LRIG3 and meningioma risk (2013) (0)
Use of DNA technology in the diagnosis of occult atherosclerotic disease (1991) (0)
Association Studies (2009) (0)
Shared heritability and functional enrichment across six solid cancers (2019) (0)
I TOMLINSON genes adenomatous polyposis and the search for modifier Explaining differences in the severity of familial (2000) (0)
COGENT cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. (2009) (0)
PO-057 Genetic interaction and pathway based discovery of key regulators in multiple myeloma (2018) (0)
Association studies using familial cases: an efficient strategy for identifying low-penetrance disease alleles. (2007) (0)
Linkage and the transmission disequilibrium test in complex traits : celiac disease as a case study. (2000) (0)
Mendelian randomization provides support for obesity as a risk factor for meningioma (2019) (0)
Title COGENT ( COlorectal cancer GENeTics ) : An international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2009) (0)
Title Replication study of SNP associations for colorectal cancer inHong (2010) (0)
Coeliac disease-associated primary small bowel malignancy: Has it previously been over-estimated? (2001) (0)
Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease. (2021) (0)
Age group General population Normal relatives from CLL families Relative risk (95% CI) P-value (Fisher's exact test) (2006) (0)
THE FREQUENCY OF THE RS55705857 RISK ALLELE IS ELEVATED AND SIMILAR IN FAMILIAL AND SPORADIC GLIOMA PATIENTS (2013) (0)
Pleiotropic Associations of r isk Variants identified for Other c ancers With l ung c ancer r isk: t he PAG e and tricl c onsortia (2014) (0)
Regions of homozygosity as risk factors for multiple myeloma (2019) (0)
Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report (2017) (0)
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology (2018) (0)
Genome-wide asociation study and meta-analysis in Northrn European populations replicate multiple colorectal cancer risk (2017) (0)
Short communication Allelic imbalance in colorectal cancer at the CRAC1 locus in early-onset colorectal cancer (2003) (0)
Germline mutations in SPI1 and MADD do not contribute to familial chronic lymphocytic leukaemia (2007) (0)
susceptibility in familial chronic lymphocytic leukemia related genetic - Linkage analysis for major histocompatibility complex (2013) (0)
Integrating genome-wide polygenic risk scores and non-genetic risk to predict colorectal cancer diagnosis: a cohort study in UK Biobank (2022) (0)
[Identification of low-penetrance alleles associated with colon cancer risk]. (2009) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2022) (0)
Edinburgh Research Explorer COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer role (2009) (0)
Comprehensive genomic testing for chronic lymphocytic leukaemia patients: WGS, one key to patient stratification (2020) (0)
Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes (2020) (0)
Explorer COGENT ( COlorectal cancer GENeTics ) : an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2017) (0)
GENE-47. EVALUATING GLIOMA RISK ASSOCIATED WITH EXTENT OF EUROPEAN ADMIXTURE IN AFRICAN-AMERICANS AND LATINOS (2017) (0)
Correction: Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer (2017) (0)
EPID-01CHICKEN POX AND GLIOMA RISK: PRELIMINARY RESULTS FROM THE GLIOGENE INTERNATIONAL CASE-CONTROL STUDY. (2015) (0)
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry (2023) (0)
Abstract 233: Evaluating glioma risk associated with extent of European admixture in African-Americans and Latinos (2018) (0)
Mendelian randomisation study of the relationship between vitamin D and risk of glioma (2018) (0)
POT1 GERMLINE MUTATIONS MAY EXPLAIN A SUBSET OF FAMILIAL GLIOMA : A REPORT FROM THE GLIOGENE CONSORTIUM (2013) (0)
Genome-wide association study of glioma and meta-analysis (2012) (0)

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