Isaac Berenblum
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Polish-born Israeli biochemist
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Isaac Berenblumbiology Degrees
Biology
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#4843
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Biochemistry
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#338
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Biology
Isaac Berenblum's Degrees
- PhD Biochemistry University of Warsaw
Why Is Isaac Berenblum Influential?
(Suggest an Edit or Addition)According to Wikipedia, Isaac Berenblum, was an Israeli biochemist, who in 1947 proposed that cancers need another trigger to grow besides mutated DNA. Awards In 1974, Berenblum was awarded the Israel Prize, in life science.In 1980, he received the Alfred P. Sloan Jr. Prize given by the General Motors Cancer Research Foundation.
Isaac Berenblum's Published Works
Published Works
- An improved method for the colorimetric determination of phosphate. (1938) (764)
- A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin (1947) (562)
- The Cocarcinogenic Action of Croton Resin (1941) (416)
- The Mechanism of Carcinogenesis. A Study of the Significance of Cocarcinogenic Action and Related Phenomena (1941) (337)
- The Role of Croton Oil Applications, Associated with a Single Painting of a Carcinogen, in Tumour Induction of the Mouse's Skin (1947) (312)
- A speculative review; the probable nature of promoting action and its significance in the understanding of the mechanism of carcinogenesis. (1954) (242)
- Sequential Aspects of Chemical Carcinogenesis: Skin (1975) (198)
- An Experimental Study of the Initiating Stage of Carcinogenesis, and a Re-examination of the Somatic Cell Mutation Theory of Cancer (1949) (181)
- The Persistence of Latent Tumour Cells Induced in the Mouse's Skin by a Single Application of 9:10-Dimethyl-1:2-Benzanthracene (1949) (174)
- Studies on the colorimetric determination of phosphate. (1938) (173)
- Carcinogenesis and tumor pathogenesis. (1954) (160)
- Carcinogenesis as a biological problem (1974) (159)
- Systemic promoting action of phorbol in liver and lung carcinogenesis in AKR mice. (1972) (95)
- A re-evaluation of the concept of cocarciongenesis. (1969) (87)
- The modifying influence of dichloro‐ethyl sulphide on the induction of tumours in mice by tar (1929) (72)
- The Significance of the Sequence of Initiating and Promoting Actions in the Process of Skin Carcinogenesis in the Mouse (1955) (65)
- The carcinogenic action of 9,10-dimethyl-1,2-benzanthracene on the skin and subcutaneous tissues of the mouse, rabbit, rat and guinea pig. (1949) (63)
- An Experimental Analysis of the “Hair Cycle Effect” in Mouse Skin Carcinogenesis (1958) (60)
- Possible Two-Stage Mechanism in Experimental Leukemogenesis (1960) (58)
- Promotion of mammary carcinogenesis and leukemogenic action by phorbol in virgin female Wistar rats. (1974) (58)
- Skin initiating action and lung carcinogenesis byderivatives of urethane (ethyl carbamate) and related compounds. (1959) (58)
- Established principles and unresolved problems in carcinogenesis. (1978) (52)
- Slow Elimination of Urethan in Relation to its High Garcinogenicity in Newborn Mice.∗ (1964) (52)
- Experimental inhibition of tumour induction by mustard gas and other compounds (1935) (49)
- Irritation and Carcinogenesis. (1944) (48)
- Two independent aspects of tumor promotion. (1981) (47)
- The Metabolism of 3,4-Benzpyrene in Mice and Rats. I. The Isolation of a Hydroxy and a Quinone Derivative, and a Consideration of Their Biological Significance (1943) (46)
- The catabolism of urethan in young mice of varying age and strain, and in x-irradiated mice, in relation to urethan carcinogenesis. (1965) (42)
- A Quantitative Study of the Systemic Initiating Action of Urethane (Ethyl Carbamate) in Mouse Skin Carcinogenesis (1957) (40)
- Regeneration of Bone Marrow Cells and Thymus induced by 19S Alpha-2 Globulin in Irradiated Mice (1968) (39)
- Carcinogenic Constituents of Coal-tar (1947) (34)
- The Metabolism of 3,4-Benzpyrene in Mice and Rats. II. The Identification of the Isolated Products as 8-Hydroxy-3,4-Benzpyrene and 3,4-Benzpyrene-5,8-Quinone (1943) (32)
- The anti-carcinogenic action of dichlorodiethylsulphide (mustard gas) (1931) (30)
- The Induction of the Initiating Phase of Skin Carcinogenesis in the Mouse by Oral Administration of Urethane (Ethyl Carbamate) (1956) (29)
- The Metabolism of Normal and Neoplastic Skin Epithelium: Evidence against the Theory that Aerobic Glycolysis Associated with a Low R.Q. is a Feature of a Disturbed Metabolism Indicative of Tumour Growth (1940) (29)
- The leukemogenic action of phorbol. (1970) (28)
- Tumour metabolism in the presence of anti-carcinogenic substances. (1936) (25)
- The Initiating Action of Ethyl Carbamate (Urethane) on Mouse Skin (1955) (25)
- INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS. (1964) (24)
- Some recent advances in skin carcinogenesis. (1957) (24)
- The rate of disappearance of 3:4-benzpyrene from the mouse after subcutaneous and intraperitoneal injection. (1942) (23)
- The carcinogenic action and metabolism of N‐hydroxyurethane in newborn mice (1966) (22)
- Distribution of C14-labeled urethans in tissues of the mouse and subcellular localization in lung and liver. (1958) (20)
- The metabolism of 3,4-benzpyrene into 8- and 10-benzpyrenols in the animal body; with an appendix on absorption spectra. (1946) (20)
- The destruction of 1:2:5:6-dibenzanthracene in the mouse. (1936) (19)
- The study of metabolic activities of small amounts of surviving tissues. (1939) (19)
- A System of Grading Carcinogenic Potency (1945) (19)
- Tumour-Formation following Freezing with Carbon Dioxide Snow. (1929) (19)
- Possible two‐stage transplacental liver carcinogenesis in c57bl/6 mice (1977) (19)
- Challenging problems in cocarcinogenesis. (1985) (18)
- The influence of croton oil and of polyethylene glycol-400 on carcinogenesis in the forestomach of the mouse. (1955) (17)
- The effect of caffeine on two-stage skin carcinogenesis and on complete systemic carcinogenesis. (1981) (17)
- The influence of dose of carcinogen, emptiness of stomach, and other factors on tumor induction in the forestomach of the mouse. (1955) (15)
- SOME PROPERTIES OF "RLP"--A FACTOR FROM SHEEP SPLEEN CAPABLE OF INHIBITING RADIATION LEUKEMOGENESIS IN MICE. (1965) (15)
- Comparative study of lung carcinogenesis, promoting action in leukaemogenesis and initiating action in skin tumorigenesis by urethane, hydrazine and related compounds (1969) (15)
- The immunological properties of proteins treated with ββ′-dichlorodiethylsulphide (mustard gas) and ββ′-dichlorodiethylsulphone (1939) (15)
- A Factor (‘RLP’) from Sheep Spleen which Inhibits Radiation Leukæmogenesis in Mice (1964) (14)
- 3: 4-Benzpyrene from Coal Tar (1945) (14)
- A Possible Two-Stage Mechanism in Rhabdomyosarcoma Induction in Rats (1962) (14)
- Carbohydrate Metabolism of Tumours (1940) (13)
- Further Investigations on the Induction of Tumours with Carbon Dioxide Snow. (1930) (13)
- Leukemogenesis by Urethan in C57B1 Mice Bearing Isologous Tissues from X-Irradiated Mice (1961) (13)
- Papilloma formation in the forestomach of the mouse following oral administration of urethan (ethyl carbamate). (1957) (13)
- 9,10-Dimethyl-1,2-Benzanthracene as a Highly Potent Carcinogen for the Rabbit's Skin (1945) (12)
- A new type of microrespirometer. (1939) (12)
- A possible in vivo skin model for tumour promoter assays. (1982) (12)
- The Induction of the Initiating Phase of Skin Carcinogenesis in the Mouse by Oral Administration of 9:10 - Dimethyl - 1:2 - Benzanthracene, 20 - Methylcholanthrene, 3:4 - Benzpyrene, and 1:2:5:6 - Dibenzanthracene (1957) (12)
- In vivo tests for a carcinogenic metabolite in plasma of animals given injections of ethyl carbamate (urethan). (1960) (12)
- On the mechanism of urethan leukemogenesis in newborn C57BL mice. II. Influence of thymectomy and of subsequent thymus reimplantation. (1966) (11)
- The Metabolism of 1,2-Benzanthracene in Mice and Rats (1943) (11)
- Metabolism of 3,4-benzopyrene. (1955) (10)
- Cancer prevention as a realizable goal (1981) (10)
- Inhibition of radiation-induced lymphatic leukemia in C57BL mice by 19S alpha-2-globulin (alpha 2-MG) from human blood serum. (1974) (10)
- Mechanism of ovarian carcinogenesis: effect of 7,12-dimethylbenz[a]anthracene administration on intrasplenic ovarian grafts in unilaterally ovariectomized C3HeB/Fe mice. (1979) (10)
- On the mechanism of urethan leukemogenesis in newborn C57BL mice. I. Influence of injections of syngeneic bone marrow cell suspensions. (1966) (10)
- The carcinogenic action in the mouse of 20-methylcholanthrene by rectal administration. (1956) (10)
- The apparent anticarcinogenic action of lanolin. (1947) (9)
- Carcinogenic Constituents of Shale Oil (1943) (9)
- Fluorescence spectrography as an aid in the identification of compounds. (1946) (9)
- The metabolism of chrysene: the isolation of 3-methoxychrysene by methylation of the phenolic metabolite of chrysene from rat faeces. (1949) (9)
- Liquor picis carbonis; a carcinogenic agent. (1948) (9)
- Metabolic Products of 3: 4-Benzpyrene (1942) (8)
- Action of Mustard Gas (ββ′-Dichlorodiethylsulphide) on Nucleoproteins (1947) (8)
- Stimulation of thymic and bone marrow regeneration in irradiated mice by protein fractions of human serum and sheep spleen. (1969) (8)
- Tritiated thymidine as a broad spectrum initiator in transplacental two‐stage carcinogenesis, with phorbol as promoter (1979) (8)
- Phorbol as a possible systemic promoting agent for skin carcinogenesis (1976) (8)
- CARCINOGENESIS IN RELATION TO SKIN CANCER (1960) (7)
- A quantitative study of the leukemogenic action of whole-body x-irradiation and urethane. I. In adult C57BL mice. (1968) (7)
- Some physical methods of investigating carcinogenic hydrocarbons. (1946) (7)
- The effect of podophyllotoxin on the skin of the mouse, with reference to carcinogenic, cocarcinogenic, and anticarcinogenic action. (1951) (6)
- Some basic problems in assessing carcinogenic risks. (1980) (6)
- Failure of bone marrow to interfere with the augmentation of x-ray leukemogenesis by urethan. (1961) (6)
- Chemical analysis of the gastric contents of the mouse. I. Description of methods and evaluation of results. (1957) (6)
- The quantitative estimation of 3:4-benzpyrene in whole animals, their tissues and excreta. (1942) (6)
- A quantitative study of the leukemogenic action of whole-body x-irradiation and urethane. II. In newborn C57BL mice. (1968) (5)
- Carcinogenesis: A broad critique. A collection of papers presented at the 20th Annual Symposium on Fundamental Cancer Research, 1966 Pp xii + 774. Williams and Williams Co., Baltimore. 1967. $16 (1968) (5)
- Failure of syngeneic bone marrow cells to protect against MC-induced lymphoma in dba-2 mice. (1968) (5)
- A Cytological Study of Bone Marrow and Peripheral Blood of Irradiated and Nonirradiated Mice Treated with 19S Alpha-2 Globulin $(\alpha _{2}\text{-}{\rm MG})$ (1971) (5)
- Effect of colchicine injection prior to the initiating phase of two-stage skin carcinogenesis in mice. (1977) (5)
- NOTE ON A STABLE SUSPENSION OF DIBENZANTHRACENE IN WATER (1932) (5)
- The Two-Stage Mechanism of Carcinogenesis in Biochemical Terms (1974) (4)
- ACTION OF ISOLOGOUS BONE MARROW FROM URETHAN-TREATED C57BL-6 MICE ON RADIATION LEUKEMOGENESIS. (1964) (4)
- Systemic promoting action and leukemogenesis in SWR mice by phorbol and structurally related polyfunctional diterpenes (1979) (4)
- An Implantor for Forming and Accurate Placing of Small Pellets. (1952) (4)
- THE LACK OF EFFECT OF URETHAN (ETHYL CARBAMATE) ON SARCOMA INDUCTION BY THE SUBCUTANEOUS INJECTION OF 3,4-BENZPYRENE. (1963) (4)
- A cytological study of bone marrow and peripheral blood of irradiated and nonirradiated mice treated with 19S alpha-2 globulin (alpha-2-MG). (1971) (4)
- Liquor Picis Carbonis (B.P.) (1948) (4)
- The Difference in Carcinogenicity Between Shale Oil and Shale. (1944) (4)
- Circumstantial evidence pointing to differences between cancers in terms of etiologic factors. (1956) (3)
- The Production of Tumours in the Fowl with a Colloidal Solution of 1: 2: 5: 6-Dibenzanthracene. (1934) (3)
- EXPERIMENTAL INDUCTION OF TUMOURS (1930) (3)
- Carcinogenicity testing for control of environmental tumor development in man. (1979) (3)
- POSSIBLE RELATIONSHIPS BETWEEN MUTAGENESIS AND CARCINOGENESIS (1972) (3)
- Chemical analysis of the gastric contents of the mouse. II. Response in acid secretion to histamine, atropine, acetylcholine, and pilocarpine. (1957) (2)
- Chemical analysis of the gastric contents of BRS mice before and after the development of spontaneous tumors in the glandular mucosa of the stomach (1958) (2)
- Further exploration of stages in carcinogenesis. (1982) (2)
- Failure of the urethane antagonist-lysergic acid-diethylamide (LSD-25)--to inhibit lung carcinogenesis or the initiating phase of skin carcinogenesis in mice. (1959) (2)
- Influence of thymectomy and subsequent thymus implantation on leukemia induction in adult C57BL mice by radiation and urethan. (1966) (2)
- Some New Implications of the Two‐Stage Mechanism in the Study of Skin Carcinogenesis (2008) (2)
- Quantitative carcinogenesis in relation to human exposures. (1988) (1)
- Action of mustard gas (beta beta '-dichlorodiethylsulphide) on nucleoproteins. (1947) (1)
- Advances in tumour pathogenesis (1959) (1)
- Carcinogenic constituents of shale oil. [Chromatographic fractionation showed presence of 3,4-benzopyrene; active materials are similar to those found in coal tar and are formed during heating] (1943) (1)
- New ideas on the biological stages of carcinogenesis. (1954) (1)
- Cancer research in historical perspective: an autobiographical essay. (1977) (1)
- Classics in oncology: The mechanism of carcinogenesis: A study of the significance of cocarcinogenic action and related phenomena (1981) (1)
- RADIATION, URETHANE, AND A "TRANSMISSIBLE FACTOR" IN EXPERIMENTAL LEUKAEMOGENESIS. (1964) (1)
- A quantitative analysis of bone marrow cell populations in irradiated and nonirradiated mice treated with 19S alpha-2 globulin (alpha-2-MG). (1971) (1)
- The metabolism of chrysene in the rat. (1945) (1)
- Man Against Cancer: The Story of Cancer Research (1952) (1)
- Prof. Fritz Weigert (1947) (1)
- Mechanisms of carcinogenesis: the role of carcinogenic metabolites. (1959) (1)
- Principles of Methodology Relating to the Potential Carcinogenicity of Medical Drugs (1967) (1)
- The Metabolism of 3,4-Benzpyrene into 8- and Benzpyrenols in the Animal Body 10- (2007) (0)
- RADIATION, URETHANE, AND A $sub 4$TRANSMISSIBLE FACTOR$sub 4$ IN EXPERIMENTAL LEUKAEMOGENESIS (1964) (0)
- Basic and Applied Research in a Small Country: The Biomedical Potential (1972) (0)
- Precision in cancer terminology. (1966) (0)
- Mode of action of carcinogenic agents. (1953) (0)
- The immunological properties of proteins treated with betabeta'-dichlorodiethylsulphide (mustard gas) and betabeta'-dichlorodiethylsulphone. (1939) (0)
- Metabolism of 3,4-Benzopyrene (1955) (0)
- Cancer Research in HistoricalPerspective: An AutobiographicalEssay (1977) (0)
- Advances in cancer research Vol. 6, edited by Alexander Haddow and Sidney Weinhouse. Pp. x + 524. Academic Press Inc., New York and London. 1962. 86s. net (1963) (0)
- The carcinogenic action of urethane. (1955) (0)
- Difference in carcinogenicity between shale oil and shale. [Blue shale oil (distilled from concentrated extract of shale) is strongly carcinogenic, but extract itself has no effect] (1944) (0)
- Science and Modern Civilization (1961) (0)
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