Didier Stainier
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Why Is Didier Stainier Influential?
(Suggest an Edit or Addition)According to Wikipedia, Didier Stainier is a Belgian/American developmental geneticist who is currently a director at the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany. Scientific career Didier Stainier studied biology in Wales , Belgium and the USA where he got a BA in 1984. He has a PhD in biochemistry and biophysics from Harvard University . During his PhD work, he investigated axon guidance and target recognition in the developing mouse with Walter Gilbert. Subsequently, he initiated the studies on zebrafish cardiac development as a Helen Hay Whitney postdoctoral fellow with Mark Fishman at the Massachusetts General Hospital .
Didier Stainier's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins (2002) (1591)
- miR-126 regulates angiogenic signaling and vascular integrity. (2008) (1551)
- A genetic screen for mutations affecting embryogenesis in zebrafish. (1996) (1369)
- Vertebrate Smoothened functions at the primary cilium (2005) (1367)
- Genetic compensation induced by deleterious mutations but not gene knockdowns (2015) (1025)
- Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes (2010) (954)
- Hematopoietic stem cells derive directly from aortic endothelium during development (2009) (916)
- The perivascular niche regulates breast tumor dormancy (2013) (874)
- Molecular control of endothelial cell behaviour during blood vessel morphogenesis (2011) (846)
- Cellular and molecular analyses of vascular tube and lumen formation in zebrafish (2005) (756)
- Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. (1998) (746)
- Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. (1996) (597)
- Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. (1995) (579)
- Genetic compensation triggered by mutant mRNA degradation (2019) (574)
- Cardiac troponin T is essential in sarcomere assembly and cardiac contractility (2002) (564)
- Selective plane illumination microscopy techniques in developmental biology (2009) (550)
- Hepatic stellate cells in liver development, regeneration, and cancer. (2013) (528)
- Genetic compensation: A phenomenon in search of mechanisms (2017) (527)
- Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. (2005) (479)
- Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. (1999) (478)
- Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies (2007) (454)
- Universal GFP reporter for the study of vascular development (2000) (448)
- Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. (2003) (445)
- Gata5 is required for the development of the heart and endoderm in zebrafish. (1999) (438)
- Optogenetic Control of Cardiac Function (2010) (411)
- A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development (2000) (402)
- Zebrafish genetics and vertebrate heart formation (2001) (392)
- Mutations affecting the development of the embryonic zebrafish brain. (1996) (383)
- The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation (2004) (373)
- Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formation. (1993) (366)
- Mutations affecting development of the zebrafish retina. (1996) (356)
- Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM). (2007) (354)
- Formation of the digestive system in zebrafish. I. Liver morphogenesis. (2003) (339)
- Mesodermal Wnt2b signalling positively regulates liver specification (2006) (333)
- Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation (2009) (331)
- Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies (2008) (331)
- Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. (2008) (329)
- Fibronectin regulates epithelial organization during myocardial migration in zebrafish. (2004) (328)
- Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors (2008) (323)
- Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. (1996) (320)
- A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula (2006) (317)
- Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development (2005) (315)
- The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. (2000) (310)
- A molecular pathway leading to endoderm formation in zebrafish (1999) (304)
- The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation. (1997) (302)
- casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish. (2001) (294)
- UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. (2001) (285)
- casanova plays an early and essential role in endoderm formation in zebrafish. (1999) (277)
- Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). (2000) (269)
- Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis (2001) (265)
- Mutations affecting craniofacial development in zebrafish. (1996) (256)
- Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System (2008) (249)
- Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish (2003) (246)
- Guidelines for morpholino use in zebrafish (2017) (240)
- Hematopoietic mutations in the zebrafish. (1996) (237)
- Patterning the zebrafish heart tube: acquisition of anteroposterior polarity. (1992) (234)
- Genetic control of single lumen formation in the zebrafish gut (2007) (232)
- In Vivo Cardiac Reprogramming Contributes to Zebrafish Heart Regeneration (2013) (229)
- Early Myocardial Function Affects Endocardial Cushion Development in Zebrafish (2004) (223)
- Zebrafish model for human long QT syndrome (2007) (221)
- Uncovering the molecular and cellular mechanisms of heart development using the zebrafish. (2012) (221)
- The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. (2000) (217)
- From endoderm formation to liver and pancreas development in zebrafish (2003) (216)
- Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint (2003) (211)
- A dual role for ErbB2 signaling in cardiac trabeculation (2010) (209)
- Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. (2010) (209)
- LITTLE FISH, BIG DATA: ZEBRAFISH AS A MODEL FOR CARDIOVASCULAR AND METABOLIC DISEASE. (2017) (208)
- microRNA-138 modulates cardiac patterning during embryonic development (2008) (208)
- High-speed imaging of developing heart valves reveals interplay of morphogenesis and function (2008) (204)
- Bmp and Fgf signaling are essential for liver specification in zebrafish (2007) (192)
- Mutations affecting development of the notochord in zebrafish. (1996) (190)
- Multiple roles for Gata5 in zebrafish endoderm formation. (2001) (190)
- Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration (2017) (189)
- Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis (2015) (186)
- Chromatin remodelling complex dosage modulates transcription factor function in heart development (2011) (186)
- Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors (2012) (186)
- A glimpse into the molecular entrails of endoderm formation. (2002) (185)
- Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. (2014) (182)
- Fgf10 regulates hepatopancreatic ductal system patterning and differentiation (2007) (180)
- Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish (2016) (173)
- Adenosine signaling promotes regeneration of pancreatic β cells in vivo. (2012) (173)
- The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors. (2007) (173)
- Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis. (2001) (172)
- Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis (2013) (170)
- Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. (1998) (166)
- Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology (2014) (166)
- In vivo cell biology: following the zebrafish trend. (2006) (164)
- Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism (2012) (158)
- Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart field. (1994) (157)
- Lessons from “Lower” Organisms: What Worms, Flies, and Zebrafish Can Teach Us about Human Energy Metabolism (2007) (157)
- A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish (2011) (157)
- Interferon gamma signaling positively regulates hematopoietic stem cell emergence. (2014) (156)
- The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish (2008) (153)
- Distinct populations of quiescent and proliferative pancreatic β-cells identified by HOTcre mediated labeling (2009) (151)
- A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene (1999) (150)
- A Cellular Framework for Gut-Looping Morphogenesis in Zebrafish (2003) (150)
- Bmp2 signaling regulates the hepatic versus pancreatic fate decision. (2008) (144)
- Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth (2016) (144)
- Transcriptional Silencing and Reactivation in Transgenic Zebrafish (2009) (143)
- A molecular mechanism for Wnt ligand-specific signaling (2018) (142)
- Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis (2007) (142)
- Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae. (2006) (142)
- Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. (2000) (139)
- Fast revascularization of the injured area is essential to support zebrafish heart regeneration (2016) (137)
- Loss-of-function genetic tools for animal models: cross-species and cross-platform differences (2016) (136)
- Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. (2009) (135)
- The POU domain protein spg (pou2/Oct4) is essential for endoderm formation in cooperation with the HMG domain protein casanova. (2004) (131)
- Mutations affecting development of the zebrafish ear. (1996) (130)
- ETS factors regulate Vegf-dependent arterial specification. (2013) (126)
- The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish (2006) (124)
- The zebrafish as a model system to study cardiovascular development. (1994) (119)
- Vegfc is required for vascular development and endoderm morphogenesis in zebrafish (2004) (119)
- Characterization of vascular mural cells during zebrafish development (2009) (119)
- Zebrafish in the study of early cardiac development. (2012) (118)
- Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish (2015) (118)
- A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. (2007) (117)
- Isolation of the zebrafish homologues for the tie‐1 and tie‐2 endothelium‐specific receptor tyrosine kinases (1998) (115)
- Iroquois homeobox gene 3 establishes fast conduction in the cardiac His–Purkinje network (2011) (114)
- High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation (2014) (111)
- The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. (2002) (110)
- glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis (2015) (109)
- Cardiac conduction is required to preserve cardiac chamber morphology (2010) (109)
- A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. (2012) (107)
- Making sense of anti-sense data. (2015) (105)
- sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development (2012) (103)
- Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. (2011) (102)
- No Organ Left Behind: Tales of Gut Development and Evolution (2005) (101)
- Pioneer neurons in the mouse trigeminal sensory system. (1990) (99)
- Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish (2010) (99)
- The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling (2009) (96)
- Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. (2001) (96)
- In vivo modulation of endothelial polarization by Apelin receptor signalling (2016) (96)
- Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish (2008) (94)
- Characterization of the Huntington's disease (HD) gene homologue in the zebrafish Danio rerio. (1998) (94)
- Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification (2016) (94)
- A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation (2016) (90)
- Rescue of Caenorhabditis elegans pharyngeal development by a vertebrate heart specification gene. (1998) (88)
- A Mutation in Zebrafish hmgcr1b Reveals a Role for Isoprenoids in Vertebrate Heart-Tube Formation (2007) (87)
- Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens. (2011) (87)
- A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation. (2000) (86)
- Three zebrafish MEF2 genes delineate somitic and cardiac muscle development in wild-type and mutant embryos (1996) (85)
- Use of three-dimensional organoids and lung-on-a-chip methods to study lung development, regeneration and disease (2018) (85)
- MicroRNA-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting Vascular Endothelial Growth Factor Signaling (2012) (82)
- Intra-endodermal interactions are required for pancreatic beta cell induction. (2008) (81)
- Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis. (1999) (80)
- Frameshift indels introduced by genome editing can lead to in-frame exon skipping (2017) (77)
- Mutations affecting neural survival in the zebrafish Danio rerio. (1996) (75)
- Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. (2008) (74)
- The basic helix‐loop‐helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver (2012) (73)
- Metabolic Regulation of Cellular Plasticity in the Pancreas (2013) (73)
- Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. (2010) (72)
- Minor class splicing shapes the zebrafish transcriptome during development (2014) (70)
- Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation (2014) (69)
- TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella (2014) (69)
- TAEL: a zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control (2017) (67)
- Conditional control of gene function by an invertible gene trap in zebrafish (2012) (66)
- Intracardiac flow dynamics regulate atrioventricular valve morphogenesis. (2014) (66)
- Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis (2013) (66)
- Cardiovascular development. Prospects for a genetic approach. (1994) (65)
- Hand2 Regulates Epithelial Formation during Myocardial Differentiation (2005) (65)
- Sheath Cell Invasion and Trans-differentiation Repair Mechanical Damage Caused by Loss of Caveolae in the Zebrafish Notochord (2017) (65)
- Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium (2019) (64)
- The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development. (2012) (64)
- Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish (2017) (63)
- Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish (2015) (62)
- Genetic Evidence for a Noncanonical Function of Seryl-tRNA Synthetase in Vascular Development (2009) (62)
- VMAT2 identified as a regulator of late-stage β-cell differentiation. (2014) (61)
- HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development (2018) (60)
- Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. (2019) (60)
- Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes (2005) (60)
- Immune responses in cardiac repair and regeneration: a comparative point of view (2018) (59)
- Real-time 3D visualization of cellular rearrangements during cardiac valve formation (2016) (58)
- Notch signaling can regulate endoderm formation in zebrafish (2004) (58)
- Multiple roles for Med12 in vertebrate endoderm development. (2008) (58)
- AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration (2020) (56)
- Implications for dorsoventral axis determination from the zebrafish mutation janus (1994) (56)
- Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration (2019) (55)
- Zebrafish: genetic and embryological methods in a transparent vertebrate embryo. (1997) (55)
- Suppression of Ptf1a Activity Induces Acinar-to-Endocrine Conversion (2011) (53)
- Radial glia regulate vascular patterning around the developing spinal cord (2016) (51)
- A window to the heart: can zebrafish mutants help us understand heart disease in humans? (2002) (51)
- Actin Binding GFP Allows 4D In Vivo Imaging of Myofilament Dynamics in the Zebrafish Heart and the Identification of Erbb2 Signaling as a Remodeling Factor of Myofibril Architecture (2014) (50)
- Cse1l Is a Negative Regulator of CFTR-Dependent Fluid Secretion (2010) (49)
- Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells (2018) (49)
- Regulation of neurocoel morphogenesis by Pard6 gamma b. (2008) (49)
- Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1 (2012) (48)
- CTCF Promotes Muscle Differentiation by Modulating the Activity of Myogenic Regulatory Factors* (2011) (48)
- Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling (2017) (47)
- Neuronal differentiation and maturation in the mouse trigeminal sensory system, in vivo and in vitro (1991) (47)
- Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair (2017) (46)
- Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. (2012) (45)
- Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. (2009) (44)
- Patterning during organogenesis: genetic analysis of cardiac chamber formation. (1999) (44)
- Pituicyte Cues Regulate the Development of Permeable Neuro-Vascular Interfaces. (2018) (43)
- Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic β-cells in zebrafish (2009) (42)
- Tension heterogeneity directs form and fate to pattern the myocardial wall (2020) (42)
- Restriction of hepatic competence by Fgf signaling (2011) (41)
- Focal adhesions are essential to drive zebrafish heart valve morphogenesis (2019) (41)
- Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish (2020) (41)
- Lipid receptors in cardiovascular development. (2003) (41)
- In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation. (2016) (39)
- N-cadherin relocalization during cardiac trabeculation (2016) (38)
- Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. (2012) (38)
- Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state (2020) (38)
- Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein. (2016) (38)
- Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification (2018) (37)
- The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling (2018) (37)
- Bone morphogenetic protein signaling governs biliary‐driven liver regeneration in zebrafish through tbx2b and id2a (2017) (37)
- Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development (2018) (37)
- Conditional mutagenesis by oligonucleotide-mediated integration of loxP sites in zebrafish (2018) (37)
- The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis (2018) (36)
- Myocardium and BMP signaling are required for endocardial differentiation (2015) (36)
- Vegf signaling promotes vascular endothelial differentiation by modulating etv2 expression. (2017) (35)
- Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1 (2012) (34)
- The monoclonal antibody B30 recognizes a specific neuronal cell surface antigen in the developing mesencephalic trigeminal nucleus of the mouse (1989) (32)
- Isl2b regulates anterior second heart field development in zebrafish (2017) (32)
- The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model (2010) (31)
- Notochord vacuoles absorb compressive bone growth during zebrafish spine formation (2020) (30)
- Notch Signaling Functions as a Cell-Fate Switch between the Endothelial and Hematopoietic Lineages (2009) (30)
- In vivo analysis of cardiomyocyte proliferation during trabeculation (2018) (30)
- Regulation of Vegf signaling by natural and synthetic ligands. (2016) (29)
- Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. (2018) (29)
- TGF-β Signaling Promotes Tissue Formation during Cardiac Valve Regeneration in Adult Zebrafish. (2019) (29)
- Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling (2019) (29)
- Transcriptional adaptation: a mechanism underlying genetic robustness (2020) (28)
- Modulation of Mammalian Cardiomyocyte Cytokinesis by the Extracellular Matrix (2020) (27)
- Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb (2013) (27)
- WNT/RYK signaling restricts goblet cell differentiation during lung development and repair (2019) (27)
- Dynamics of zebrafish fin regeneration using a pulsed SILAC approach (2015) (27)
- Vertebrate Hedgehog signaling: cilia rule (2010) (27)
- Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish (2018) (27)
- Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model (2019) (26)
- The guts of endoderm formation. (2002) (26)
- Thyroid Hormone Coordinates Pancreatic Islet Maturation During the Zebrafish Larval-to-Juvenile Transition to Maintain Glucose Homeostasis (2017) (26)
- Regulation of posterior body and epidermal morphogenesis in zebrafish by localized Yap1 and Wwtr1 (2017) (26)
- Dachshund homologues play a conserved role in islet cell development. (2010) (25)
- Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. (2018) (25)
- Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis. (2019) (25)
- Nfatc1 Promotes Interstitial Cell Formation During Cardiac Valve Development in Zebrafish (2020) (24)
- Mir-126 is a conserved modulator of lymphatic development. (2018) (24)
- Endocardial cushion formation in zebrafish. (2002) (23)
- Proteolysis regulates cardiomyocyte maturation and tissue integration (2017) (23)
- Laminin β1a controls distinct steps during the establishment of digestive organ laterality (2013) (23)
- Intrinsic and extrinsic modifiers of the regulative capacity of the developing liver (2012) (23)
- CNS-resident progenitors direct the vascularization of neighboring tissues (2017) (23)
- A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development (2019) (23)
- Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function (2020) (23)
- Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis (2013) (22)
- Transcriptional adaptation in Caenorhabditis elegans (2020) (22)
- The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish (2018) (22)
- Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish (2019) (22)
- Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease (2018) (22)
- Hepatocyte Growth Factor Signaling in Intrapancreatic Ductal Cells Drives Pancreatic Morphogenesis (2013) (22)
- Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko (2008) (22)
- Transient cardiomyocyte fusion regulates cardiac development in zebrafish (2017) (21)
- The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish (2003) (21)
- Developmental biology: Twisting the body into shape (2003) (20)
- Organ Function as a Modulator of Organ Formation: Lessons from Zebrafish. (2016) (20)
- Loss of Dnmt 1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration (2009) (20)
- deLiver'in regeneration: injury response and development. (2010) (19)
- Genetic compensation triggered by mutant mRNA degradation (2018) (18)
- Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos (2018) (18)
- The B30 ganglioside is a cell surface marker for neural crest-derived neurons in the developing mouse. (1991) (18)
- A new mode of pancreatic islet innervation revealed by live imaging in zebrafish (2018) (18)
- Wnt/β‐catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating notch activity (2018) (17)
- Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration (2021) (16)
- Genetics in Light of Transcriptional Adaptation. (2020) (16)
- Vascular and blood gene expression. (1999) (16)
- Regulation of Vegf signaling by natural and synthetic ligands. (2016) (16)
- Translational profiling through biotinylation of tagged ribosomes in zebrafish (2014) (16)
- On the development of the hepatopancreatic ductal system. (2017) (15)
- The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies (2017) (15)
- Notch signaling regulates venous arterialization during zebrafish fin regeneration (2015) (15)
- Fibrillin-2b regulates endocardial morphogenesis in zebrafish. (2012) (15)
- Intra-endodermal interactions are required for pancreatic β-cell induction (2008) (15)
- Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. (2012) (15)
- Endoderm specification and liver development. (2016) (15)
- Pattern Formation: Swimming in Retinoic Acid (2002) (15)
- Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development. (2016) (14)
- Metabolic modulation regulates cardiac wall morphogenesis in zebrafish (2019) (14)
- Recent insights into vascular development from studies in zebrafish (2018) (14)
- Origin and function of activated fibroblast states during zebrafish heart regeneration (2022) (14)
- Recovery of adult zebrafish hearts for high-throughput applications. (2014) (14)
- No stem cell is an islet (yet). (2006) (14)
- Mutations Affecting Cardiac Development in Zebrafish (1999) (13)
- Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists (2018) (13)
- In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos (2003) (13)
- Ccn2a is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish (2020) (11)
- Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise (2018) (11)
- The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling (2020) (11)
- The HeArt of Regeneration (2006) (11)
- Whole-Organism Chemical Screening Identifies Modulators of Pancreatic β-Cell Function (2018) (11)
- Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development (2021) (11)
- Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis (2019) (10)
- Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish (2018) (10)
- Regulation of neurocoel morphogenesis by Pard6 γ b (2008) (9)
- Genotype-Phenotype Relationships in the Context of Transcriptional Adaptation and Genetic Robustness. (2021) (9)
- Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract (2020) (8)
- Cardiac development. (2004) (8)
- Spatial domains in the developing forebrain: developmental regulation of a restricted cell surface protein. (1991) (8)
- Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development. (2021) (8)
- Cavin4b/Murcb Is Required for Skeletal Muscle Development and Function in Zebrafish (2016) (8)
- The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish (2018) (8)
- Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration (2018) (8)
- Effects of pristine or contaminated polyethylene microplastics on zebrafish development. (2022) (7)
- Noncanonical activity of seryl-transfer RNA synthetase and vascular development. (2009) (7)
- Defective adgra2 (gpr124) splicing and function in zebrafish ouchless mutants (2017) (7)
- Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function (2019) (7)
- Hhex regulates the specification and growth of the hepatopancreatic ductal system. (2019) (7)
- Pushing Yap into the Nucleus with Shear Force. (2017) (7)
- A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration (2022) (7)
- nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish. (2005) (7)
- Tek (Tie2) is not required for cardiovascular development in zebrafish (2020) (6)
- Tek/Tie2 is not required for cardiovascular development in zebrafish. (2020) (6)
- Endothelial ontogeny and the establishment of vascular heterogeneity (2021) (5)
- Innervation modulates the functional connectivity between pancreatic endocrine cells (2020) (5)
- Cardiomyocyte heterogeneity during zebrafish development and regeneration. (2021) (5)
- Author response: Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration (2017) (4)
- Author response: Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis (2015) (4)
- Corrigendum to “The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development” [Dev. Biol. 363 (2012) 438–450] (2012) (4)
- Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos (2022) (4)
- Sculpting the heart: Cellular mechanisms shaping valves and trabeculae. (2021) (4)
- Fishing Out a New Heart (2002) (4)
- The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression (2020) (4)
- Author response: Radial glia regulate vascular patterning around the developing spinal cord (2016) (4)
- An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea (2022) (3)
- Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells (2020) (3)
- Hhex regulates the specification and growth of the hepatopancreatic ductal system (2018) (3)
- Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures (2021) (3)
- Whole-organism screening for modulators of fasting metabolism using transgenic zebrafish. (2015) (3)
- Development. Fishing out a new heart. (2002) (3)
- Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in wildtype and cloche/npas4l mutant zebrafish embryos (2020) (3)
- The stress responsive gene ankrd1a is dynamically regulated during skeletal muscle development and upregulated following cardiac injury in border zone cardiomyocytes in adult zebrafish. (2021) (3)
- New insights into benzo[⍺]pyrene osteotoxicity in zebrafish. (2021) (2)
- An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates (2022) (2)
- Author response: Notochord vacuoles absorb compressive bone growth during zebrafish spine formation (2020) (2)
- Abstract 19863: The Shear Stress-induced Human Long Non-coding RNA Lassie Regulates Endothelial Cell-cell Junctions (2017) (2)
- Integration of multiple imaging platforms to uncover cardiovascular defects in adult zebrafish (2021) (2)
- Genome-wide strategies reveal target genes of Npas4l associated with cardiovascular development in zebrafish (2018) (2)
- The E3 ubiquitin-protein ligase Rbx1 regulates cardiac wall morphogenesis in zebrafish. (2021) (2)
- Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2 (2022) (2)
- Tie1 regulates zebrafish cardiac morphogenesis through tolloid-like 1 expression. (2020) (2)
- Ccn2a/Ctgfa is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish. (2020) (2)
- A δ-cell subpopulation with a pro-β-cell identity contributes to efficient age-independent recovery in a zebrafish model of diabetes (2022) (2)
- A novel Slit–Robo–miR-218 signaling axis regulates VEGF-mediated heart tube formation in zebrafish (2010) (2)
- Fin ray branching is defined by TRAP+ osteolytic tubules (2022) (2)
- Conserved and context-dependent roles for Pdgfrb signaling during zebrafish vascular mural cell development (2021) (2)
- Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract (2020) (2)
- Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract (2019) (1)
- Hand2 Regulates Epithelial Formation during Myocardial Differentiation (2005) (1)
- Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish (2019) (1)
- Angiogenesis during zebrafish development (2003) (1)
- Endothelial signals regulate hepatocyte apico-basal polarization in zebrafish (2008) (1)
- Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. (2023) (1)
- The developing epicardium regulates cardiac chamber morphogenesis by promoting cardiomyocyte growth (2021) (1)
- Thyroid hormones regulate goblet cell differentiation and Fgf19-Fgfr4 signaling. (2021) (1)
- Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish (2021) (1)
- Endothelial TGF-β signaling instructs smooth muscle development in the cardiac outflow tract (2020) (1)
- Parental mutations influence wild-type offspring via transcriptional adaptation (2022) (1)
- Cardiac Development in Vertebrates (2001) (1)
- Author response: Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state (2020) (1)
- Developmental biology: It takes muscle to make blood cells (2014) (1)
- Abstract 1062: Kcnh2 Mutations Cause Silent Ventricle in Zebrafish Null Model (2006) (1)
- WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme (2022) (1)
- Svep1 stabilises developmental vascular anastomosis in reduced flow conditions (2021) (1)
- Developmental Biology: Physics Adds a Twist to Gut Looping (2011) (1)
- Coronary revascularization is regulated by epicardial and endocardial cues and forms a scaffold for cardiomyocyte repopulation (2020) (1)
- Roles of Bmp, Fgf and Wnt signaling in liver formation and recovery in zebrafish embryos (2008) (0)
- Author response: Metabolic modulation regulates cardiac wall morphogenesis in zebrafish (2019) (0)
- Klf2 is required for myocardial wall integrity in zebrafish (2016) (0)
- Mechanism of genetic interaction between Hnf1b and Wnt/ß-Catenin signaling for specification of hepatopancreatic progenitors (2011) (0)
- Editorial Board Members (2017) (0)
- Integration of multiple imaging platforms to uncover cardiac defects in adult zebrafish (2020) (0)
- Editorial Board (2017) (0)
- Author response: Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification (2021) (0)
- Editorial Board Members (2012) (0)
- Endodermal Cells Differentiate Into Endothelial Cells to Function as a Vascular Niche for Hematopoietic Stem and Progenitor Cells (2021) (0)
- Editorial Board Members (2008) (0)
- Document S1. Table S1 (2013) (0)
- Document S2. Article plus Supplemental Information (2013) (0)
- Editorial Board Members (2016) (0)
- Abstract 327: ETS Factors Regulate the VEGF-Dependent, Arterial-Specific Expression of Dll4 (2014) (0)
- Identification of novel loci associated with respiratory disease by a forward genetic approach in mouse (2015) (0)
- Genetic interaction between diabetes genes hnf1b and wnt2bb specifies hepatopancreatic progenitors (2011) (0)
- Phenotype of Wild-Type and cfk-/- Embryos at 36 hpf (2011) (0)
- Editorial Board Members (2014) (0)
- Author response: Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration (2019) (0)
- The origin of cardiac excitation in zebrafish (2012) (0)
- 2SY04-5 A novel mutation, s202 affects early endothelial cell differentiation in zebrafish (2003) (0)
- The G-protein coupled receptor Agtrl1 regulates early development of myocardial progenitors (2010) (0)
- Editorial board members (2010) (0)
- sufficient for early endoderm formation in zebrafish encodes a novel Sox-related protein necessary andcasanova (2001) (0)
- Editorial Board Members (2010) (0)
- Keynote Speakers (2020) (0)
- FGF10 regulates hepatopancreatic ductal system differentiation (2006) (0)
- Author response: A new mode of pancreatic islet innervation revealed by live imaging in zebrafish (2018) (0)
- Editorial Board (2017) (0)
- Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair (2017) (0)
- Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function (2020) (0)
- Author response: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures (2021) (0)
- Editorial board members (2009) (0)
- Author response: Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration (2018) (0)
- Basic science: Beta cells, islets and complications (2021) (0)
- Immune responses in cardiac repair and regeneration: a comparative point of view (2018) (0)
- Lifting the cloche: Jeroen Bakkers interviews Didier Stainier. (2023) (0)
- Developmental Cell Forum Making Sense of AntiSense Data (2015) (0)
- Endothelial and non-endothelial responses to estrogen excess during development lead to vascular malformations (2018) (0)
- Regulation of cardiomyocyte behavior by Neuregulin signaling (2017) (0)
- Gpr126 domains control different cellular mechanisms of ventricular chamber development (2021) (0)
- Transient cardiomyocyte fusion regulates cardiac development in zebrafish (2017) (0)
- Author response: The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling (2018) (0)
- Elys deficiency constrains Kras-driven tumour burden by amplifying oncogenic stress (2021) (0)
- Editorial Board (2017) (0)
- Editorial Board Members (2015) (0)
- O30. Hepatopancreatic development and function in zebrafish (2010) (0)
- Regulation of endodermal cell migration by Rac1 during zebrafish gastrulation (2010) (0)
- Abstract 16353: miR-10 Regulates Angiogenesis through VEGF Signaling Titration (2012) (0)
- Abstract 283: Nppa Marks A Subset Of Embryonic Cardiomyocytes Predestined To Form Trabeculae In Zebrafish (2014) (0)
- Herbert Alternative Mode of Blood Vessel Formation Arterial-Venous Segregation by Selective Cell Sprouting : An (2012) (0)
- Slit2 controls endocardial cell migration during zebrafish heart morphogenesis (2009) (0)
- Author response: Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract (2020) (0)
- A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish (2022) (0)
- Editorial board members (2006) (0)
- Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease (2018) (0)
- Molecular-Genetic Analysis of the silent heart Mutation in Zebrafish (1999) (0)
- Role of tight junction proteins in zebrafish liver morphogenesis (2009) (0)
- A mechanism for Wnt ligand-specific Frizzled signaling. (2018) (0)
- ptf1a determines pancreatic exocrine versus endocrine fates (2007) (0)
- Editorial Board Members (2022) (0)
- WITHDRAWN: ptf1a determines pancreatic exocrine versus endocrine fates (2007) (0)
- Role of the hypoxia-inducible factor pathway in cardiovascular system development in zebrafish (2016) (0)
- Editorial Board (2015) (0)
- Editorial Board (2016) (0)
- MIR-182 is a Tbx5 effector during heart development in zebrafish (2018) (0)
- Author response: A δ-cell subpopulation with a pro-β-cell identity contributes to efficient age-independent recovery in a zebrafish model of diabetes (2022) (0)
- Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner (2023) (0)
- Author response: Transcriptional adaptation in Caenorhabditis elegans (2019) (0)
- Multiple pkd and piezo gene family members are required for atrioventricular valve formation (2023) (0)
- Correction (1981) (0)
- Editorial Board Members (2011) (0)
- Angioblast Behavior in Arterial-Venous Segregation (2010) (0)
- Author response: Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish (2018) (0)
- Neural crest cells are required for autonomic innervation of the endocrine pancreas (2016) (0)
- Paramvir Dehal Vertebrate Origins : Insights into Chordate and Ciona intestinalis The Draft Genome (2013) (0)
- Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development (2018) (0)
- The Max Planck Institute for Heart and Lung Research Curiosity-Driven Basic Research to Fight Cardio-Pulmonary Diseases. (2017) (0)
- A Cellular Framework for Gut-looping (2007) (0)
- 09-P010 A nonsense mutation in the TFIIH p52 gene causes abnormal rRNA processing in the zebrafish intestinal mutant, sycorax (2009) (0)
- Editorial Board (2016) (0)
- Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification (2021) (0)
- Editorial Board (2017) (0)
- A δ-cell subpopulation with a pro-β-cell identity confers efficient age-independent recovery in a zebrafish model of diabetes (2021) (0)
- Entrails, heart, brain, limbs, and lymphatics- a recipe for success? (2003) (0)
- Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification (2021) (0)
- Editorial Board Members (2015) (0)
- Editorial Board (2016) (0)
- Extracellular matrix dynamics reveals the building plan for cardiac trabeculation (2017) (0)
- Imaging heart development and function in zebrafish (2013) (0)
- Formation Sprouting : An Alternative Mode of Blood Vessel Arterial-Venous Segregation by Selective Cell (2010) (0)
- ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma (2023) (0)
- Cse1l Is a Negative Regulator of CFTR-Dependent Fluid Secretion (2010) (0)
- Abstract 1574: The Hippo pathway regulates liver development and tumorigenesis in zebrafish. (2013) (0)
- Whole organism chemical screening to identify modulators of beta cell function (2016) (0)
- Cardiac valve regeneration in adult zebrafish: importance of TGFß signaling in new tissue formation (2019) (0)
- Abstract 5151: Yap reprograms glutamine metabolism and supports growth during liver development and tumorigenesis (2015) (0)
- HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development (2018) (0)
- Editorial Board Members (2012) (0)
- Correction: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella (2014) (0)
- Adgrg6/Gpr126 is required for myocardial Notch activity and N-cadherin localization to attain trabecular identity (2022) (0)
- The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis (2018) (0)
- Editorial Board (2017) (0)
- The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies (2017) (0)
- Cellular and genetic dissection of the cardiac electric system (2007) (0)
- 09-P008 – Withdrawn (2009) (0)
- Oestrogen excess induces instability and loss of arterial identity in the forming vascular system (2016) (0)
- Editorial Board Members (2009) (0)
- Basic and clinical science posters: Beta cells, islets and stem cells (2019) (0)
- Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells (2018) (0)
- Faculty Opinions recommendation of Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. (2019) (0)
- Editorial Board Members (2013) (0)
- Didier Stainier: how function follows form. Interview by Sedwick Caitlin. (2013) (0)
- Editorial Board (2017) (0)
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