Paul Stewart
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British endocrinologist
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Endocrinology
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Biology
Paul Stewart 's Degrees
- PhD Endocrinology University of Oxford
Why Is Paul Stewart Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul Michael Stewart FMedSci FRCP is Dean of Medicine and Health at the University of Leeds and an Honorary Consultant Endocrinologist at the Leeds Teaching Hospitals NHS Trust. He is also currently Vice President of the Academy of Medical Sciences and the editor-in-chief of The Journal of Clinical Endocrinology and Metabolism.
Paul Stewart 's Published Works
Published Works
- The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. (2008) (2057)
- 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. (2004) (976)
- Does central obesity reflect “Cushing's disease of the omentum”? (1997) (788)
- Extrarenal Expression of 25-Hydroxyvitamin D3-1α-Hydroxylase1 (2001) (758)
- MINERALOCORTICOID ACTIVITY OF LIQUORICE: 11-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY COMES OF AGE (1987) (695)
- 11 beta-Hydroxysteroid dehydrogenase. (1994) (623)
- Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. (2008) (618)
- Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist (2001) (591)
- Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. (2001) (520)
- Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. (2000) (499)
- Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. (2001) (459)
- Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity. (1999) (455)
- Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle. (1988) (442)
- Corticosteroid insufficiency in acutely ill patients. (2003) (423)
- 11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. (2005) (375)
- Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study (2004) (337)
- Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS) (2010) (333)
- Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly. (2004) (328)
- Mortality in patients with pituitary disease. (2010) (321)
- Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. (2002) (318)
- Licorice inhibits corticosteroid 11 beta-dehydrogenase of rat kidney and liver: in vivo and in vitro studies. (1989) (315)
- Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency (2003) (311)
- Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis. (1995) (308)
- Urine Steroid Metabolomics as a Biomarker Tool for Detecting Malignancy in Adrenal Tumors (2011) (307)
- Reduced placental 11beta-hydroxysteroid dehydrogenase type 2 mRNA levels in human pregnancies complicated by intrauterine growth restriction: an analysis of possible mechanisms. (2001) (303)
- Watershed, reach, and riparian influences on stream fish assemblages in the Northern Lakes and Forest Ecoregion, U.S.A. (2003) (280)
- Urinary free cortisone and the assessment of 11β‐hydroxysteroid dehydrogenase activity in man (1996) (278)
- Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. (2009) (277)
- Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation. (2012) (276)
- Primary medical therapy for acromegaly: an open, prospective, multicenter study of the effects of subcutaneous and intramuscular slow-release octreotide on growth hormone, insulin-like growth factor-I, and tumor size. (2002) (272)
- Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study (2010) (264)
- Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene (1996) (252)
- Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) (2015) (250)
- Modulation of 11β‐Hydroxysteroid Dehydrogenase Isozymes by Proinflammatory Cytokines in Osteoblasts: An Autocrine Switch from Glucocorticoid Inactivation to Activation (2001) (240)
- Hyperandrogenemia Predicts Metabolic Phenotype in Polycystic Ovary Syndrome: The Utility of Serum Androstenedione (2014) (237)
- A RATIONAL APPROACH FOR ASSESSING THE HYPOTHALAMO-PITUITARY-ADRENAL AXIS (1988) (236)
- Hypertension and the cortisol-cortisone shuttle. (2003) (235)
- Hexose-6-phosphate Dehydrogenase Knock-out Mice Lack 11β-Hydroxysteroid Dehydrogenase Type 1-mediated Glucocorticoid Generation* (2006) (229)
- 11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess (2014) (224)
- 1alpha-Hydroxylase and the action of vitamin D. (2000) (207)
- Extrarenal Expression of 25-Hydroxyvitamin D 3-1 a-Hydroxylase * (2001) (206)
- Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity. (2002) (203)
- Autocrine Metabolism of Vitamin D in Normal and Malignant Breast Tissue (2005) (201)
- Osteoblastic 11β‐Hydroxysteroid Dehydrogenase Type 1 Activity Increases With Age and Glucocorticoid Exposure (2002) (201)
- Mineralocorticoid activity of carbenoxolone: contrasting effects of carbenoxolone and liquorice on 11 beta-hydroxysteroid dehydrogenase activity in man. (1990) (199)
- Human kidney 11 beta-hydroxysteroid dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform. (1994) (197)
- Differentiation of Adipose Stromal Cells: The Roles of Glucocorticoids and 11β-Hydroxysteroid Dehydrogenase. (1999) (195)
- Regulation of Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Adipose Tissue: Tissue-Specific Induction by Cytokines. (2001) (191)
- Conventional pituitary irradiation is effective in lowering serum growth hormone and insulin-like growth factor-I in patients with acromegaly. (2006) (190)
- Deficient inactivation of cortisol by 11β‐hydroxysteroid dehydrogenase in essential hypertension (1993) (189)
- The Ontogeny of 25-Hydroxyvitamin D3 1α-Hydroxylase Expression in Human Placenta and Decidua (2002) (186)
- Mineralocorticoid excess and inhibition of 11 β‐hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome (1992) (177)
- Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. (2005) (176)
- Outcome of surgery for acromegaly--the experience of a dedicated pituitary surgeon. (1999) (170)
- A switch in dehydrogenase to reductase activity of 11 beta-hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells. (2002) (170)
- Expression and functional consequences of 11beta-hydroxysteroid dehydrogenase activity in human bone. (2000) (167)
- Licorice inhibits 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action. (1993) (167)
- 5 α-reductase activity in polycystic ovary syndrome (1990) (165)
- 11Beta-hydroxysteroid dehydrogenase type 1 and its role in the hypothalamus-pituitary-adrenal axis, metabolic syndrome, and inflammation. (2009) (162)
- Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5. (2004) (161)
- 11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle (2009) (161)
- Adrenal corticosteroid biosynthesis, metabolism, and action. (2005) (160)
- Diagnosis of primary aldosteronism: from screening to subtype differentiation (2005) (157)
- Modulation of 11β-Hydroxysteroid Dehydrogenase Isozymes by Growth Hormone and Insulin-Like Growth Factor: In Vivo and In Vitro Studies1 (1999) (156)
- Expression of 25-Hydroxyvitamin D3-1α-Hydroxylase in the Human Kidney (1999) (156)
- 11 beta-Hydroxysteroid dehydrogenase activity in Cushing's syndrome: explaining the mineralocorticoid excess state of the ectopic adrenocorticotropin syndrome. (1995) (155)
- Minireview: hexose-6-phosphate dehydrogenase and redox control of 11{beta}-hydroxysteroid dehydrogenase type 1 activity. (2005) (154)
- ACTH deficiency, higher doses of hydrocortisone replacement, and radiotherapy are independent predictors of mortality in patients with acromegaly. (2009) (153)
- Depot long-acting somatostatin analog (Sandostatin-LAR) is an effective treatment for acromegaly. (1995) (151)
- Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase. (2001) (147)
- Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells (2004) (139)
- 11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects. (2013) (139)
- CA-Repeat polymorphism in intron 1 of HSD11B2 : effects on gene expression and salt sensitivity. (2000) (138)
- Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. (2008) (137)
- Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years. (2012) (134)
- The long-term predictive accuracy of the short synacthen (corticotropin) stimulation test for assessment of the hypothalamic-pituitary-adrenal axis. (2006) (131)
- Type 2 11 beta-hydroxysteroid dehydrogenase in human fetal tissues. (1994) (131)
- Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study. (2016) (130)
- Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement. (2013) (130)
- NMR‐based metabolomic analysis of cerebrospinal fluid and serum in neurological diseases – a diagnostic tool? (2009) (128)
- Long‐term therapy with long‐acting octreotide (Sandostatin‐LAR®) for the management of acromegaly (1998) (127)
- Regulation of Lipogenesis by Glucocorticoids and Insulin in Human Adipose Tissue (2011) (125)
- The ontogeny of 25-hydroxyvitamin D(3) 1alpha-hydroxylase expression in human placenta and decidua. (2002) (122)
- Increased Expression of Mineralocorticoid Effector Mechanisms in Kidney Biopsies of Patients With Heavy Proteinuria (2005) (122)
- Local and systemic glucocorticoid metabolism in inflammatory arthritis (2007) (119)
- Premature adrenarche: novel lessons from early onset androgen excess. (2011) (119)
- Detection of human 11β-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts (1995) (118)
- Tissue localization of 11β-hydroxysteroid dehydrogenase and its relationship to the glucocorticoid receptor (1992) (117)
- Impaired Glucose Tolerance and Insulin Resistance Are Associated With Increased Adipose 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Elevated Hepatic 5α-Reductase Activity (2008) (115)
- Human 11β-hydroxysteroid dehydrogenase: Studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue (1997) (114)
- Expression profiles for steroidogenic enzymes in adrenocortical disease. (2005) (114)
- Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin. (2011) (114)
- Relative influence of variables at multiple spatial scales on stream macroinvertebrates in the Northern Lakes and Forest ecoregion, U.S.A. (2003) (113)
- 11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects. (2013) (112)
- Life expectancy following surgery for pituitary tumours (1999) (111)
- Constitutive Expression of 25-Hydroxyvitamin D3-1α-Hydroxylase in a Transformed Human Proximal Tubule Cell Line: Evidence for Direct Regulation of Vitamin D Metabolism by Calcium. (1999) (111)
- Systemic hypertension and glaucoma: mechanisms in common and co-occurrence (2005) (109)
- Cortisol metabolism in hypertension. (2006) (108)
- Type 2 11β-hydroxysteroid dehydrogenase in foetal and adult life (1995) (106)
- Growth Hormone, Insulin-Like Growth Factor-I and the Cortisol-Cortisone Shuttle (2001) (106)
- Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome. (2009) (104)
- 11beta-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation. (2005) (104)
- Our Response to COVID-19 as Endocrinologists and Diabetologists (2020) (102)
- Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation (2006) (102)
- Tissue-specific Cushing's syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action. (2003) (101)
- Biphasic elevation of [Ca(2+)](i) in individual human spermatozoa exposed to progesterone. (2000) (98)
- Glucocorticoid regulation of p450 aromatase activity in human adipose tissue: gender and site differences. (2002) (97)
- Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue. (2004) (97)
- Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis. (2007) (96)
- Exploring the pathogenesis of IIH: An inflammatory perspective (2008) (96)
- Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol (2015) (96)
- Epithelial cell localization of type 2 11 beta-hydroxysteroid dehydrogenase in rat and human colon. (1994) (96)
- 11beta-hydroxysteroid dehydrogenase type 1 activity predicts the effects of glucocorticoids on bone. (2003) (95)
- Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly. (2002) (94)
- Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in the human kidney. (1999) (93)
- Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase. (1999) (92)
- Prereceptor regulation of glucocorticoid action by 11β‐hydroxysteroid dehydrogenase: a novel determinant of cell proliferation (2002) (92)
- Altered Nuclear Receptor Corepressor Expression Attenuates Vitamin D Receptor Signaling in Breast Cancer Cells (2006) (89)
- The Birmingham pituitary database: auditing the outcome of the treatment of acromegaly (1995) (89)
- Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency. (2008) (89)
- Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation? (2010) (86)
- Deletion of Hexose-6-phosphate Dehydrogenase Activates the Unfolded Protein Response Pathway and Induces Skeletal Myopathy* (2008) (85)
- A Switch in Hepatic Cortisol Metabolism across the Spectrum of Non Alcoholic Fatty Liver Disease (2012) (85)
- No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: in vivo and in vitro studies. (2005) (84)
- Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. (2001) (84)
- A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis (2008) (83)
- Regulation of 11 beta-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes. (1998) (83)
- Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial. (2014) (83)
- Adrenal insufficiency: review of clinical outcomes with current glucocorticoid replacement therapy (2015) (83)
- Apparent mineralocorticoid excess syndrome: an overview. (2004) (82)
- 11β‐Hydroxysteroid dehydrogenase: implications for clinical medicine (1996) (81)
- Glucocorticoid activity, inactivity and the osteoblast. (1999) (81)
- Reduced glucocorticoid production rate, decreased 5α-reductase activity and adipose tissue insulin sensitization following weight loss (2008) (81)
- Immunodetection of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Mineralocorticoid Target Tissues: Evidence for Nuclear Localization. (1997) (81)
- Modulation of 11β-Hydroxysteroid Dehydrogenase (11βHSD) Activity Biomarkers and Pharmacokinetics of PF-00915275, a Selective 11βHSD1 Inhibitor (2008) (81)
- Regulation—the real threat to clinical research (2008) (80)
- Characterization of 11beta-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines. (1999) (79)
- Hypopituitarism: clinical features, diagnosis, and management. (2008) (79)
- Expression of epidermal growth factor (EGF), its receptor, and related oncoprotein (erbB-2) in human pituitary tumors and response to EGF in vitro. (1994) (79)
- Radiotherapy for non-function pituitary tumours. (1998) (79)
- Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock. (2006) (78)
- Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P. (2007) (77)
- A National Strategy for the Conservation of Native Freshwater Mollusks* (2016) (76)
- Apparent mineralocorticoid excess in a Brazilian kindred: hypertension in the heterozygote state (1997) (76)
- Loss of estrogen inactivation in colonic cancer. (1999) (75)
- MicroRNA-24 Is a Novel Regulator of Aldosterone and Cortisol Production in the Human Adrenal Cortex (2013) (74)
- Efficacy of Sandostatin® LAR® (long‐acting somatostatin analogue) is similar in patients with untreated acromegaly and in those previously treated with surgery and/or radiotherapy (2004) (74)
- Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1 (2012) (73)
- High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. (2016) (72)
- 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 IN DIFFERENTIATING OMENTAL HUMAN PREADIPOCYTES: FROM DE-ACTIVATION TO GENERATION OF CORTISOL (2002) (71)
- Expression and putative role of 11 beta-hydroxysteroid dehydrogenase isozymes within the human eye. (2001) (71)
- Absence of Cushingoid phenotype in a patient with Cushing's disease due to defective cortisone to cortisol conversion. (2002) (71)
- Molecular Basis for Hypertension in the “Type II Variant” of Apparent Mineralocorticoid Excess (1998) (71)
- Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes (2010) (71)
- Apparent mineralocorticoid excess: Type I and type II (1996) (71)
- Functional Expression, Characterization, and Purification of the Catalytic Domain of Human 11-β-Hydroxysteroid Dehydrogenase Type 1* (2001) (70)
- Is subclinical Cushing's syndrome an entity or a statistical fallout from diagnostic testing? Consensus surrounding the diagnosis is required before optimal treatment can be defined. (2010) (70)
- Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome (2005) (68)
- Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue. (2007) (67)
- Central hypoadrenalism. (2014) (67)
- Medical therapy in patients with acromegaly: predictors of response and comparison of efficacy of dopamine agonists and somatostatin analogues. (2009) (66)
- Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease. (2010) (65)
- Adrenal vein sampling for Primary Aldosteronism: time for a reality check (2010) (64)
- 11β-Hydroxysteroid dehydrogenases, cell proliferation and malignancy (2003) (64)
- Gender-Specific Differences in Skeletal Muscle 11β-HSD1 Expression Across Healthy Aging. (2015) (64)
- Adrenal Incidentaloma (2020) (64)
- Cardiovascular function and glucocorticoid replacement in patients with hypopituitarism (1995) (64)
- Androgen Receptor–Mediated Regulation of the &agr;-Subunit of the Epithelial Sodium Channel in Human Kidney (2005) (63)
- 11β-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function* (2007) (63)
- Influence of habitat, water quality, and land use on macro-invertebrate and fish assemblages of a southeastern coastal plain watershed, USA (2004) (63)
- Chronic nicotine ingestion and atrial fibrillation. (1985) (62)
- Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss (2009) (62)
- Late-Onset Apparent Mineralocorticoid Excess Caused by Novel Compound Heterozygous Mutations in the HSD11B2 Gene (2003) (62)
- 11β-Hydroxysteroid dehydrogenase: unexpected connections (2003) (61)
- Land use, habitat, and water quality effects on macroinvertebrate communities in three watersheds of a lake michigan associated marsh system (2000) (60)
- Isoforms of 11β-hydroxysteroid dehydrogenase in human granulosa-lutein cells (1997) (60)
- The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease. (2012) (59)
- Modulation of glucocorticoid action and the treatment of type-2 diabetes. (2007) (59)
- Renal TLR4 mRNA Expression Correlates with Inflammatory Marker MCP-1 and Profibrotic Molecule TGF-β1 in Patients with Chronic Kidney Disease (2011) (59)
- Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes. (2006) (58)
- Demonstration of Proof of Mechanism and Pharmacokinetics and Pharmacodynamic Relationship with 4′-Cyano-biphenyl-4-sulfonic Acid (6-Amino-pyridin-2-yl)-amide (PF-915275), an Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1, in Cynomolgus Monkeys (2008) (58)
- Adipophilin distribution and colocalisation with lipid droplets in skeletal muscle (2009) (58)
- Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo. (2013) (57)
- Adrenal Insufficiency in Critical Illness (2007) (57)
- 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression (2017) (57)
- Academic medicine: a faltering engine (2002) (56)
- Ontogeny and sexual dimorphic expression of mouse type 2 11β-hydroxysteroid dehydrogenase (1997) (56)
- 1-Hydroxylase and the action of vitamin D (2000) (56)
- 5 alpha-reductase activity in polycystic ovary syndrome. (1990) (55)
- Cortisol to cortisone: Glucocorticoid to mineralocorticoid (1995) (55)
- Characterization of Aromatase and 17β‐Hydroxysteroid Dehydrogenase Expression in Rat Osteoblastic Cells (1998) (54)
- Abnormal expression of 11β-hydroxysteroid dehydrogenase type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation (2003) (54)
- Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency. (2016) (54)
- Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake (2013) (53)
- Home administration of lanreotide Autogel® by patients with acromegaly, or their partners, is safe and effective (2008) (53)
- Expression of 11 beta-hydroxysteroid dehydrogenase isozymes and corticosteroid hormone receptors in primary cultures of human trophoblast and placental bed biopsies. (2001) (53)
- Cortisone-reductase deficiency associated with heterozygous mutations in 11β-hydroxysteroid dehydrogenase type 1 (2011) (52)
- Oestrogen inactivation in the colon: analysis of the expression and regulation of 17 β -hydroxysteroidehydrogenase isozymes in normal colon and colonic cancer (2000) (52)
- Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation. (2003) (52)
- 11β-Hydroxysteroid dehydrogenase in the rat adrenal (1996) (51)
- Assessing the HPA axis in patients with pituitary disease: a UK survey (2006) (50)
- 11 beta-Hydroxysteroid dehydrogenase deficiency and glucocorticoid status in patients with alcoholic and non-alcoholic chronic liver disease. (1993) (50)
- A Benthic Community Index for streams in the Northern Lakes and Forests Ecoregion (2003) (50)
- Assessing the hypothalamo-pituitary-adrenal axis in patients on long-term glucocorticoid therapy: the short synacthen versus the insulin tolerance test. (1995) (50)
- Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study (2005) (49)
- Development, calibration, and validation of a littoral zone plant index of biotic integrity (PIBI) for lacustrine wetlands (2008) (48)
- Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells (2012) (48)
- Analysis of the 11β-Hydroxysteroid Dehydrogenase Type 2 Gene (HSD11B2) in Human Essential Hypertension (2005) (48)
- A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause (2012) (47)
- Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation (2013) (47)
- Estrogen metabolism and malignancy: analysis of the expression and function of 17β-hydroxysteroid dehydrogenases in colonic cancer (2001) (46)
- Pituitary surgery for acromegaly (1999) (46)
- Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis. (2006) (46)
- The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue. (2002) (46)
- Novel homozygous splice acceptor site GnRH receptor (GnRHR) mutation: human GnRHR "knockout". (2002) (45)
- Regulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity and mRNA in human choriocarcinoma cells. (1996) (45)
- The pituitary–adrenal axis and body composition (2008) (45)
- Mineralocorticoid hypertension and congenital deficiency of 11β‐hydroxysteroid dehydrogenase in a family with the syndrome of‘apparent’mineralocorticoid excess (1995) (45)
- The hypothalamo‐pituitary‐adrenal axis across the normal menstrual cycle and in polycystic ovary syndrome (1993) (45)
- Identification of VDR-Responsive Gene Signatures in Breast Cancer Cells (2007) (45)
- Regulation of vitamin D-1alpha-hydroxylase in a human cortical collecting duct cell line. (2001) (45)
- Cortisol as a mineralocorticoid in human disease (1999) (44)
- Development of multimetric indices of biotic integrity for riverine and palustrine wetland plant communities along Southern Lake Michigan (2001) (44)
- Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity. (2003) (43)
- Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1. (2011) (43)
- 1,25-dihydroxyvitamin D3 regulates estrogen metabolism in cultured keratinocytes. (1997) (43)
- Clinical and biochemical response following withdrawal of a long‐acting, depot injection form of octreotide (Sandostatin‐LAR®) (1999) (42)
- Expression of renal 11β-hydroxysteroid dehydrogenase type 2 is decreased in patients with impaired renal function (2005) (42)
- Hypoglycemia with enhanced hepatic glycogen synthesis in recombinant mice lacking hexose-6-phosphate dehydrogenase. (2007) (41)
- Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium. (1999) (41)
- Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging. (2005) (40)
- Mortality following pituitary radiotherapy (2007) (40)
- Novel aspects of hormone action: Intracellular ligand supply and its control by a series of tissue specific enzymes (1992) (40)
- Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue. (2008) (40)
- Variants implicated in cortisone reductase deficiency do not contribute to susceptibility to common forms of polycystic ovary syndrome (2006) (40)
- Regulation of sodium-potassium adenosine triphosphate subunit gene expression by corticosteroids and 11 beta-hydroxysteroid dehydrogenase activity. (1994) (40)
- Localization of renal 11 beta-dehydrogenase by in situ hybridization: autocrine not paracrine protector of the mineralocorticoid receptor. (1991) (40)
- Current Therapy for Acromegaly (2000) (39)
- 11-Beta-hydroxysteroid dehydrogenase activity and gene expression in the hypertensive Bianchi—Milan rat (1993) (39)
- 11β-Hydroxysteroid dehydrogenase activity and corticosteroid hormone action (1994) (39)
- Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis (2012) (39)
- Role of growth factors and estrogen as modulators of growth, differentiation, and expression of gonadotropin subunit genes in primary cultured sheep pituitary cells. (1994) (39)
- 7 11-hydroxysteroid dehydrogenase (1994) (39)
- Acute regulation of the bovine gene for the steroidogenic acute regulatory protein in ovarian theca and adrenocortical cells. (2000) (37)
- Molecular basis for the Apparent Mineralocorticoid Excess Syndrome in the Oman population (2004) (37)
- Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess. (1997) (37)
- Type 2 11 beta-hydroxysteroid dehydrogenase in foetal and adult life. (1995) (37)
- Pegvisomant: an advance in clinical efficacy in acromegaly. (2003) (37)
- Growth hormone secreting pituitary carcinoma: a case report and literature review (1992) (37)
- Dose Dependency of Iatrogenic Glucocorticoid Excess and Adrenal Insufficiency and Mortality: A Cohort Study in England (2019) (36)
- Human Δ4-3-oxosteroid 5β-reductase (AKR1D1) deficiency and steroid metabolism (2008) (36)
- Adrenal suppression in bronchiectasis and the impact of inhaled corticosteroids (2008) (36)
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- Adrenal 11β-hydroxysteroid dehydrogenase (1996) (24)
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- Growth Hormone Therapy for Hypopituitary Adults: Time for Re-appraisal (2000) (21)
- Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease (2016) (21)
- The pathophysiology of circulating corticotropin-releasing hormone-binding protein levels in the human. (1998) (21)
- 11beta-hydroxysteroid dehydrogenase: unexpected connections. (2003) (21)
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- Mutations in the 11 beta-hydroxysteroid dehydrogenase type II enzyme associated with hypertension and possibly stillbirth. (1997) (21)
- Regulation of 11 â-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes (1997) (21)
- Diminished 11β-hydroxysteroid dehydrogenase type 2 activity is associated with decreased weight and weight gain across the first year of life. (2014) (21)
- Analysis of the 11beta-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) in human essential hypertension. (2005) (20)
- Clinical Endocrinology goes electronic (2001) (20)
- Common Variation at the 11-&bgr; Hydroxysteroid Dehydrogenase Type 1 Gene Is Associated With Left Ventricular Mass (2011) (20)
- Can licorice lick colon cancer? (2009) (20)
- Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa. (2002) (20)
- Radioiodine therapy for hyperthyroidism in young patients--perception of risk and use. (1993) (20)
- 11 beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in the rat colon. (1993) (20)
- Modified-Release Hydrocortisone: Is It Time to Change Clinical Practice? (2019) (19)
- Induction of hepatic 11β‐hydroxysteroid dehydrogenase type 1 in patients with alcoholic liver disease (2008) (19)
- A Male Twin Infant with Skull Deformity and Elevated Neonatal 17–Hydroxyprogesterone: A Prismatic Case of P450 Oxidoreductase Deficiency (2004) (19)
- Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity. (2002) (19)
- Diatom (Bacillariophyta) community response to water quality and land use (1999) (19)
- Biochemistry and physiology of hexose-6-phosphate knockout mice (2011) (19)
- Association studies between the HSD11B2 gene (encoding human 11beta-hydroxysteroid dehydrogenase type 2), type 1 diabetes mellitus and diabetic nephropathy. (2002) (18)
- Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by diuretics and the renin-angiotensin-aldosterone axis. (1999) (18)
- Application of an index of biotic integrity for dunal, palustrine wetlands: emphasis on assessment of nonpoint source landfill effects on the Grand Calumet Lagoons (1998) (18)
- Development of a Stream Habitat Index for the Northern Lakes and Forests Ecoregion (2002) (18)
- Life History Study of Procambarus suttkusi in Southeastern Alabama (2008) (17)
- Expression of 11beta-hydroxysteroid dehydrogenase (11betaHSD) proteins in luteinizing human granulosa-lutein cells. (2003) (17)
- The short Synacthen test: is less best? (1999) (17)
- Organochlorines, Mercury, and Selenium in Great Blue Heron Eggs from Indiana Dunes National Lakeshore, Indiana (1998) (16)
- Characterisation of the prereceptor regulation of glucocorticoids in the anterior segment of the rabbit eye. (2006) (16)
- First trimester diagnosis of adenosine deaminase deficiency (1987) (16)
- The future of somatostatin analogue therapy. (1999) (16)
- 11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension (2020) (16)
- Health Care Burden in Patients With Adrenal Insufficiency (2017) (16)
- Acromegaly – Diagnosis and Clinical Management (2016) (16)
- TNFα regulates cortisol metabolism in vivo in patients with inflammatory arthritis (2014) (16)
- Expression of renal 11beta-hydroxysteroid dehydrogenase type 2 is decreased in patients with impaired renal function. (2005) (16)
- Inherited forms of mineralocorticoid hypertension (2011) (16)
- Mortality and hypopituitarism. (1999) (15)
- Phospholipids, sterol carrier protein2 and adrenal steroidogenesis. (1985) (15)
- Nematode assemblages in the Gulf of Mexico continental shelf collected during a two-year survey (2017) (15)
- 8 Increased vasoconstriction to glucocorticoids in essential hypertension: 11??-hydroxysteroid dehydrogenase deficiency revisited (1991) (15)
- Current and Recent Historical Freshwater Mussel Assemblages in the Gulf Coastal Plains (2006) (15)
- Maternal iodine status, intrauterine growth, birth outcomes and congenital anomalies in a UK birth cohort (2020) (15)
- Structure and function of fish communities in the southern Lake Michigan basin with emphasis on restoration of native fish communities (1999) (15)
- Polycyclic aromatic hydrocarbon concentrations, mutagenicity, and Microtox® acute toxicity testing of Peruvian crude oil and oil-contaminated water and sediment (2014) (15)
- Improving outcomes in patients with adrenal insufficiency: a review of current and future treatments (2014) (14)
- Diagnosis and Treatment of ACTH Deficiency (2005) (14)
- Genotype-phenotype correlations of mutations and polymorphisms in HSD11B2, the gene encoding the kidney isozyme of 11beta-hydroxysteroid dehydrogenase. (2000) (14)
- Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments. (2012) (14)
- Biomarkers of hypothalamic–pituitary–adrenal axis activity in mice lacking 11β-HSD1 and H6PDH (2012) (14)
- Lithium Carbonate – a Competitive Aldosterone Antagonist? (1988) (14)
- Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis (2015) (14)
- Distributional Survey of Crayfish (Crustacea: Decapoda) in Wadeable Streams in the Coastal Plains of Southeastern Alabama (2010) (14)
- IGF-1, IGFBP-3 and ALS in adult patients with chronic kidney disease. (2010) (13)
- Can 11β-Hydroxysteroid Dehydrogenase Activity Predict the Sensitivity of Bone to Therapeutic Glucocorticoids in Inflammatory Bowel Disease? (2011) (13)
- Diatom and protozoan species accrual on artificial substrates in lentic habitats (1985) (13)
- Dexamethasone-suppressible hypertension (2000) (13)
- Differences in the modulation of P4501A1 and epoxide hydratase expression by benz[a]anthracene and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse embryo versus mouse hepatoma-derived cell lines (1990) (13)
- Mutations of key hydrophobic surface residues of 11β‐hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression system (2009) (13)
- Isoforms of 11beta-hydroxysteroid dehydrogenase in human granulosa-lutein cells. (1997) (13)
- Development of an Index of Biotic Integrity for a Southeastern Coastal Plain Watershed, USA 1 (2007) (12)
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- Improving clinical research (2003) (12)
- Life history and host fish identification for Fusconaia burkei and Pleurobema strodeanum (Bivalvia: Unionidae) (2008) (12)
- Nematode and copepod diversity (2012) from Louisiana near the Deepwater Horizon oil spill (2014) (12)
- Progesterone is extensively metabolized in osteoblasts: implications for progesterone action on bone. (2008) (12)
- Renal PPARγ mRNA expression increases with impairment of renal function in patients with chronic kidney disease (2010) (12)
- Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy (2018) (12)
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- Development and Use of a Sedimentation Risk Index for Unpaved Road‐Stream Crossings in the Choctawhatchee Watershed 1 (2009) (12)
- Extensive experience in the management of macroprolactinomas (2014) (12)
- A Multi-Year Survey of Meiofaunal Abundance From the Northern Gulf of Mexico Continental Shelf and Slope (2012) (12)
- Sediment Chemistry and Meiofauna from the Northern Gulf of Mexico Continental Shelf (2014) (11)
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- Toxicity Of Sodium Dodecyl Sulfate tO Federally Threatened and Petitioned Freshwater Mollusk Species (2016) (11)
- Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue (2011) (11)
- Cushing's syndrome in women with polycystic ovaries and hyperandrogenism (2007) (11)
- Expression and functional consequences of oestrogen and progesterone receptors in human insulinomas. (2007) (11)
- The low-dose corticotropin-stimulation test revisited: the less, the better? (2009) (11)
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- LITHIUM INHIBITS THE ACTION OF FLUDROCORTISONE ON THE KIDNEY (1987) (10)
- Cell-intrinsic regulation of murine dendritic cell function and survival by prereceptor amplification of glucocorticoid. (2013) (10)
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- Induction of hepatic 11beta-hydroxysteroid dehydrogenase type 1 in patients with alcoholic liver disease. (2008) (9)
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- Acute Toxicity of Chloride, Potassium, Nickel, and Zinc to Federally Threatened and Petitioned Mollusk Species (2018) (8)
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- University of Birmingham 11{beta}-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle (2011) (8)
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- Macrohabitat Partitioning of Crayfish Assemblages in Wadeable Streams in the Coastal Plains of Southeastern Alabama (2010) (7)
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- Differential sediment stability for two federally threatened and one common species of freshwater mussels in Southeastern Coastal Plain Streams, USA (2017) (5)
- Acute Toxicity Testing of Crude Oil Using Piaractus brachypomus, and Pimephales promelas (2013) (5)
- Macroinvertebrate assemblages associated with patterns in land use and water quality (2003) (5)
- PERSPECTIVES ON THE CONTROLLED PROPAGATION , AUGMENTATION , AND REINTRODUCTION OF FRESHWATER MUSSELS ( MOLLUSCA : BIVALVIA : UNIONOIDA ) (2017) (5)
- Evaluating tertiary adrenal insufficiency in rheumatology patients on long‐term systemic glucocorticoid treatment (2020) (5)
- Response signatures of four biological indicators to an iron and steel industrial landfill (2003) (5)
- Instream Habitat Associations among Three Federally Threatened and a Common Freshwater Mussel Species in a Southeastern Watershed (2015) (4)
- Evidence for the use of igf-I as a predictor of mortality in acromegaly is lacking. (2004) (4)
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- Adrenal function: An overlooked cause of glucocorticoid deficiency? (2009) (4)
- Circulating cortisone, biochemical bone markers and bone density (2004) (4)
- Microhabitat Associations among Three Federally Threatened and a Common Freshwater Mussel Species (2015) (4)
- Local cortisol generation by human macrophage subsets by 11[beta]-hydroxysteroid dehydrogenase type 1 enzyme and its role in ocular immune privilege (2008) (4)
- Cytochrome P450 induction in Ictalurus punctatus following exposure to wastewater treatment plant effluent (2009) (4)
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- Glucocorticoid metabolic pathways in human orbital adipose tissue: a comparison with subcutaneous and omental depots (2007) (3)
- Field and model-based evaluation of a low-cost sampling protocol for a coordinated, crayfish life-history sampling effort (2015) (3)
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- Hyperandrogenaemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione (2014) (3)
- Comprar Oxford Textbook of Endocrinology and Diabetes 2Ed | Melanie C. Davies | 9780199235292 | Oxford University Press (2011) (3)
- Historical vs. Current Biological Assemblages in the Little Choctawhatchee Watershed, Southeastern AL (2013) (3)
- Growth Rates and Age Estimations of the Fuzzy Pigtoe, Pleurobema strodeanum: A Species Proposed for Listing under the Endangered Species Act (2013) (3)
- Fetal origins of adult disease: tracing and recruitment of offspring whose mothers participated in a trial of nutritional supplementation during pregnancy – the Sorrento experience (2004) (3)
- 6-Phosphogluconate dehydrogenase: an NADPH-generating enzyme in the lumen of the endoplasmic reticulum (2010) (2)
- 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) mRNA expression in liver of patients with non-alcoholic steatohepatitis (2007) (2)
- Maternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder (2020) (2)
- Differences in the modulation of P450IA1 and epoxide hydratase expression by benz[a]anthracene and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse embryo versus mouse hepatoma-derived cell lines. (1990) (2)
- Estimation of Apparent Survival, Detectability, and Density of Three Federally Threatened Mussel Species in a Small Watershed (2017) (2)
- A recurrent rash treated by oophorectomy. (2002) (2)
- Past, Present, and Future Nutrient Quality of a Small Southeastern River: A Pre-Dam Assessment (2013) (2)
- The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy (2020) (2)
- Increased systemic and adipose 11β-HSD1 activity in idiopathic intracranial hypertension (2022) (2)
- Assessment of Watershed-Lake Interactions Influencing the Cultural Eutrophication of Little Crooked & Crooked Lakes, Indiana (1993) (2)
- Advances in medical therapy for pituitary disease: treating patients with growth hormone excess and deficiency (1993) (2)
- 11 (cid:1) -Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response (2004) (2)
- Modification of calcium sensing receptor expression modulates 25-hydroxyvitamin D3-1alpha-hydroxylase activity in a human proximal tubule cell line (2002) (2)
- Urinary steroid metabolite profiling in 11[beta]-HSD1 and H6PDH transgenic mice (2010) (2)
- Impact of Glucocorticoids upon Lipogenesis and beta-Oxidation in Skeletal Muscle. (2010) (2)
- Implications of chinook salmon presence on water quality standards in a Great Lakes area of concern (2004) (2)
- 11β-hydroxysteroid dehydrogenase type 1 and age-associated muscle weakness in mice: implications for human ageing (2014) (2)
- Use of Long-Acting Somatostatin Analogs in Treating Acromegaly (1995) (2)
- Reproduction and the shuttle (1993) (2)
- Monogenic forms of hyperandrogenism due to defects in cortisol metabolism (2007) (2)
- A putative role for 11β-Hydroxysteroid dehydrogenase 1 in the regulation of cerebrospinal fluid dynamics (2007) (1)
- The Effect of Endogenous Cushing Syndrome on All-cause and Cause-specific Mortality (2022) (1)
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- Cytochrome P450 Induction and Gene Expression in Channel Catfish (Ictalurus Punctatus) Following Wastewater Treatment Plant Effluent Exposure in Field and Laboratory Settings (2010) (1)
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- 11[beta]-HSD1KO mice are protected from glucocorticoid dependent age-associated muscle atrophy (2013) (1)
- Regulation of insulin signalling across differentiation and following glucocorticoid treatment in human skeletal myocytes (2007) (1)
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- Differential transcription of 11[beta]-hydroxylase and aldosterone synthase alleles in human adrenocortical tissue (2009) (1)
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- Autocrine Activation of Glucocorticoids in Osteoblasts Increases with Age and Glucocorticoid Exposure (2002) (1)
- Tara (Caesalpinia spinosa) in Natural and Agroforestry Systems under an Altitudinal Gradient in the Peruvian Andes: Responses to Soil and Climate Variation (2023) (1)
- Therapeutic patenting for glucocorticoid-induced osteoporosis (2000) (1)
- Colorectal screening guidelines in acromegaly. Authors' reply (2003) (1)
- Is increased 11[beta]-HSD1 expression a key factor underpinning intrinsic and extrinsic skin aging? (2010) (1)
- Depot specific differences in lipogenesis in human adipose tissue (2008) (1)
- Regulation of 11 (cid:226) -hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes (1997) (1)
- TNF[alpha] directly regulates in vivo corticosteroid metabolism in inflammatory arthritis (2013) (1)
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- Expression and Functional Role for the Serum and Glucocorticoid Regulated Kinase, and the Epithelial Sodium Channel in Human Ocular Ciliary Epithelium (2002) (1)
- Transcriptional regulation of 11beta-hydroxysteroid dehydrogenase type 1 under the synergistic control of glucocorticoids and cytokines (2007) (1)
- Differential effects of glucocorticoids on fibroblasts: mechanisms underlying the adverse features of Cushing's (2008) (1)
- Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone (2020) (1)
- Urinary Steroid Profiling as a High-Throughput Screening Tool for the Detection of Malignancy in Patients with Adrenal Tumors (2010) (1)
- Fishes of the Choctawhatchee River System in Southeastern Alabama and Northcentral Florida (2015) (1)
- Conservatism of Confined Disposal Facilities Based on the Biological Stability and Integrity of Plant Communities: A Case Study in the Laurentian Great Lakes Basin (2002) (1)
- Oxygen tension regulates placental 11beta-hydroxysteroid dehydrogenase type 2 (2002) (1)
- Serine phosphorylation of IRS-1 as a mechanism of glucocorticoid induced insulin resistance in mouse C2C12 myotubes (2008) (1)
- Glucocorticoids and bone mineral content in the childhood nephrotic syndrome. (2004) (1)
- Regulation of the human 11beta-hydroxysteroid dehydrogenase gene by glucocorticoids (2003) (1)
- The Effects of Experimental Manipulations of Substrata and Nutrients on a Colonizing Diatom Community (1991) (1)
- The role of local corticosteroid generation in inflammation-associated bone loss (2004) (1)
- Murine expression of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) and hexose-6-phosphate dehydrogenase (H6PDH) (2005) (1)
- WATER TEMPERATURE EFFECTS ON GROWTH, FEED UTILIZATION AND SURVIVAL OF BLACK PACU (Colossoma macropomum) FINGERLINGS (2011) (1)
- Environmental Pollution, Climate Change, and a Critical Role for the Endocrinologist. (2021) (1)
- 13.9 Organization of diabetes care (2011) (1)
- Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients. (2021) (1)
- Effect of AZD4017, a Selective 11β-HSD1 Inhibitor, on Bone Turnover Markers in Postmenopausal Osteopenia (2022) (1)
- Ghrelin inhibits proliferation of breast cell lines acting via the growth hormone secretagogue receptor (GHS-R) (2002) (0)
- NMR based metabolomic analysis of CSF in neurological diseases: A diagnostic tool? (2008) (0)
- Depot specific glucocorticoid regulation of key components of the insulin signalling cascade in human adipose tissue (2005) (0)
- Increased HOXA10 expression in late gestation: A novel target for hormonal regulation in placenta and decidua (2002) (0)
- M018: Urinary free cortisol/cortisone ratio as index of 11β HSD2 activity in “essential” hypertension (2000) (0)
- Local inflammation activates the renal vitamin D hormonal system in human kidneys (2004) (0)
- MON-157 The Effect of Exogenous Cushing’s Syndrome on All-Cause and Cause-Specific Mortality: A Systematic Review (2020) (0)
- A Bone to Pick with Local Glucocorticoid Activation (2003) (0)
- MicroRNA expression profiling of non-tumorous adrenal tissue and modulation of 11[beta]-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes by miR-24 (2010) (0)
- Immunofluorescent visualisation of focal adhesion kinase in human skeletal muscle and its associated microvasculature (2012) (0)
- Abdominal obesity is associated with a decreased hepatic mRNA expression of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) in patients with non-alcoholic steatohepatitis (NASH) (2007) (0)
- Molecular basis of a new form of congenital adrenal hyperplasia (2004) (0)
- The Hypertensiogenetic Steroid 19-nor-Progesterone does not Influence Cortisol Inactivation by 11β-Hydroxysteroid Dehydrogenase Type 2 (2009) (0)
- Lack of beneficial metabolic profile in liver-specific 11[beta]-hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) knockout mice (2011) (0)
- Effect of different hydrocortisone (HC) replacement regimens on free serum cortisol and tissue cortisol exposure in hypopituitary men (2010) (0)
- 8.2 Pregnancy-related disorders (2011) (0)
- Mineralocorticoid action in essential hypertension (2008) (0)
- 8.1 Female endocrinology and ovarian disorders (2011) (0)
- Part 11 Endocrinology of cancer (2011) (0)
- 11β-Hydroxysteroid Dehydrogenases, Aqueous Humour Corticosteroids, and Glaucoma (2002) (0)
- 13.4.9 Non-biological technologies in glucose sensing (2011) (0)
- The role of gucocorticoid metabolism in osteosarcoma pathogenesis and treatment (2009) (0)
- Cerebrospinal fluid production: a role for 11 beta-hydroxysteroid dehydrogenase type 1? (2004) (0)
- Part 1 Principles of international endocrine practice (2011) (0)
- Inflammatory stimuli increase local cortisol production in osteoblasts in vitro and in vivo. (2000) (0)
- NMR-Based Metabolomic Analysis of Cerebrospinal Fluid and Serum in Neuro-Ophthalmological and Neurological Diseases - A Diagnostic Tool? (2009) (0)
- Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese children (2007) (0)
- Glucocorticoids, liver, fat and metabolic syndrome (2008) (0)
- Increasing fracture risk with age: Possible role of local corticosteroid generation (2002) (0)
- 3.3 Thyrotoxicosis and related disorders (2011) (0)
- Local and systemic consequences of glucocorticoid metabolism in synovium (2007) (0)
- Chapter 109 – Mineralocorticoid Deficiency (2016) (0)
- Heparan sulfate determines the modes of diffusion of fibroblast growth factor 2 within the pericellular matrix (2011) (0)
- HSD11B1 promoter binding of the NF-[kappa]B p65 subunit in response to TNF-[alpha] suppresses 11[beta]-HSD1 expression and activity in C2C12 muscle cells (2012) (0)
- Regulation of 11[beta]-hydroxysteroid dehydrogenase type 1 by NF-[kappa]B in stromal cells: towards tissue specific enzyme inhibition (2011) (0)
- Congenital heart disease in the adolescent: an Iowa perspective. (1984) (0)
- 13.8 Mental health and diabetes mellitus (2011) (0)
- IL-1 and glucocorticoids synergistically enhance 11beta-hydroxysteroid dehydrogenase expression in osteoblastic MG-63 cells: a novel mechanism for steroid induced bone loss (2005) (0)
- 9.3 Evaluation of the male patient with suspected hypogonadism and/or infertility (2011) (0)
- 2.3 Aetiology, pathogenesis, and management of disease of the pituitary (2011) (0)
- University of Birmingham Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids (2010) (0)
- Mortality and Specific Causes of Death in Endogenous Cushing’s Syndrome: A Systematic Review, Meta-Analysis and Meta-Regression (2021) (0)
- Letter re: Monitoring the response to treatment in acromegaly. (2005) (0)
- Adipocyte size increases with BMI, but is unrelated to 11 beta-hydroxysteroid dehydrogenase type 1 expression (2003) (0)
- Age-dependent increase in the expression/activity of 11[beta]-HSD1 in key metabolic tissues may underpin the ageing phenotype notably sarcopenia (2012) (0)
- 11[beta]-HSD1 knockout mice are protected from the adverse metabolic effects of exogenous glucocorticoid excess (2013) (0)
- Factors associated with response to medical therapy in patients with Acromegaly (2008) (0)
- Impact of synovial fibroblasts on adipose tissue (2011) (0)
- 9.5 Exogenous factors and male reproductive health (2011) (0)
- Growth hormone increases fat mass in patients with simple obesity (2002) (0)
- Groundwater recharge from Long Lake, Indiana Dunes National Lakeshore (1992) (0)
- Chapter 2. Impacts of Human Society on the Riverine System — Past and Present (1992) (0)
- Chapter 4. Changes in Societal Activities and Demands (1992) (0)
- Effects of contaminated dredge spoils on wetland plant communities: A literature review (2003) (0)
- Industrial landfill affects on fish communities at Indiana Dunes National Lakeshore (INDU) (1995) (0)
- revisão Apparent Mineralocorticoid Excess Syndrome: An Overview (2004) (0)
- Contributors and Participants (1982) (0)
- Landfill impacts on aquatic plant communities and tissue metal levels at Indiana Dunes National Lakeshore (1995) (0)
- 20 year experience in the surgical management of cushing's disease in a UK tertiary referral centre (2011) (0)
- Relationships between Fish Assemblages and Organochloride Insecticides in Sediment and Fish Tissue in South Central Kansas (2002) (0)
- Computer Simulation of the Great Marsh Hydrology of Indiana (1995) (0)
- Diatom and protozoan community analysis and colonization on artificial substrates in lentic habitats (1985) (0)
- Urinary steroid profile in patients with primary adrenal insufficiency under conventional glucocorticoid replacement: a case control study (2018) (0)
- 11beta-hydroxysteroid dehydrogenase is an early and essential marker of human adipogenesis (2006) (0)
- Chapter 1. What is Happening To Our Surface Waters (1992) (0)
- Chapter 8. Options for the Future (1992) (0)
- 24-hour urinary glucocorticoid metabolites are associated with hyperinsulinaemia independent of BMI in patients with the polycystic ovary syndrome (2012) (0)
- Use of the morning urinary cortisol to creatinine ratio in the diagnosis of mild Cushing's disease in patients with discordant test results (2008) (0)
- Chapter 3. The Impacts of Population Growth and Movement (1992) (0)
- Phase II study of the impact of AZD4017, a selective 11β-HSD1 inhibitor, on osteocalcin in post-menopausal osteopenia (2020) (0)
- Chapter 7. How Have Our Surface Waters Changed (1992) (0)
- Chapter 5. Federal and State Laws, Regulations and Management (1992) (0)
- Polycyclic aromatic hydrocarbon concentrations, mutagenicity, andMicrotox® acute toxicity testing of Peruvian crude oil and oil-contaminated water and sediment (2014) (0)
- Toxicity of contaminants in lagoons and pannes of the Indiana Dunes National Lakeshore (1995) (0)
- Chapter 6. Effects on Pollution of Laws and Regulations Versus Voluntary Efforts (1992) (0)
- Part 12 Obesity, lipids, and metabolic disorders (2011) (0)
- COVID‐19‐related adrenal haemorrhage: Multicentre UK experience and systematic review of the literature (2023) (0)
- Autocrine Metabolism ofVitamin D in Normal and Malignant BreastTissue (2005) (0)
- Association between serum insulin-like growth factor-1 and serum growth hormone levels across an oral glucose tolerance test in assessing disease activity in acromegaly (2004) (0)
- Part 2 Pituitary and hypothalamic diseases (2011) (0)
- Bartonella henselae in inflammatory bowel disease (2001) (0)
- Testosterone increases expression of the alpha-subunit of the epithelial sodium channel (alpha-ENAC) in the human renal cell line HKC-8 (2005) (0)
- Part 3 The thyroid (2011) (0)
- Adipose depot specific regulation of insulin signalling by glucocorticoids (2012) (0)
- Effect of secreted frizzled-related protein 2 (sFRP2) from adipose tissue on pancreatic cell function. (2012) (0)
- Adrenal incidentaloma and subclinical Cushing's syndrome (2012) (0)
- Neuroendocrine Disorders and Reproduction (2002) (0)
- Mechanistic studies oftheinhibition ofhepatic uroporphyrinogen decarboxylase inC57BL/10micebyiron-hexachlorob enzene synergism (1986) (0)
- Metabolites and Lifestyle - A Link with Primary Open Angle Glaucoma? (2012) (0)
- 3.4 Hypothyroidism and pregnancy- and growth-related thyroid disorders (2011) (0)
- Absence of hexose-6-phosphate dehydrogenase specifically induces skeletal myopathy in mice (2009) (0)
- Lack of association between polymorphic markers within 11b-hydroxysteroid dehydrogenase type 1 gene (HSD11B1) and obesity (2002) (0)
- Should we treat subclinical Cushing's syndrome? (2016) (0)
- Part 6 Neuroendocrine tumours and genetic disorders (2011) (0)
- Truncal fat distribution is associated with enhanced glucocorticoid excretion, increased 5[alpha]-reductase activity and higher insulin resistance independent of BMI in women with polycystic ovary syndrome (2013) (0)
- Refolding and purification of recombinant human hexose-6-phosphate dehydrogenase from bacterial inclusion bodies (2005) (0)
- Monitoring acromegaly disease activity with growth hormone and insulin like growth factor-I in 501 patients (2008) (0)
- Abnormal expression of 11beta-hydroxysteroid dehydrogenase 2 in primary cultures of human pituitary adenomas (2003) (0)
- Hexose 6-phosphate dehydrogenase expression confers reductase activity upon 11 beta-HSD1 in adipose tissue (2004) (0)
- Locally generated glucocorticoids, rather than pro-inflammatory cytokines, directly regulate synovial DKK-1 expression in inflammatory arthritis (2009) (0)
- Differential effects of P450 oxidoreductase mutants on CYP17 activity provides evidence for an alternative pathway in human androgen biosynthesis (2007) (0)
- Apparent Mineralocorticoid Excess (2019) (0)
- What is the association between opiate substitution treatment and survival and long term cessation of injecting in injecting drug users ? (2010) (0)
- Decreased 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys (2007) (0)
- Hepatic 11[beta]-hydroxysteroid dehydrogenase type 1 expression is dynamically related across the liver lobule and is linked to metabolic status (2011) (0)
- Prostaglandin synthesis in adipose tissue from women with simple obesity - differences between omental and subcutaneous depots (2005) (0)
- A patient with recurrent sweating. (1998) (0)
- Suppression of 11[beta]-hydroxysteroid dehydrogenase type 1 target gene regulation by hypoxia (2016) (0)
- Glucocorticoids enhance insulin sensitivity in human hepatocytes (2013) (0)
- Glucocorticoid metabolism in mouse osteoblasts: a model for the effects of local glucocorticoid generation on bone (2006) (0)
- Part 9 Male hypogonadism and infertility (2011) (0)
- 11[beta] HSD1KO mice resist aged associated decline in markers of brown adipose tissue function (2014) (0)
- Part 10 Endocrinology of ageing and systemic disease (2011) (0)
- A characterisation of novel lipase expression and glucocorticoid regulation of lipolysis in human adipose tissue (2007) (0)
- Depot specific differences in the sensitivity to glucocorticoid and insulin action in human adipose tissue (2011) (0)
- Cortisol decreases lipogenesis in human hepatocytes (2011) (0)
- University of Birmingham 11-hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension (2020) (0)
- Testosterone regulates renal expression of the alpha-subunit of the epithelial sodium channel (alpha-ENaC) (2004) (0)
- RATIONAL TESTING : Investigating hypertension in a young person (2009) (0)
- Part 13 Diabetes mellitus (2011) (0)
- Regulation of de novo lipogenesis in human liver by 5[alpha]-reductase (2012) (0)
- Systemic Carbenoxolone Reduces Intraocular Pressure in Patients with Ocular Hypertension (2002) (0)
- Hepatic 11[beta]-hydroxysteroid dehydrogenase type 1 is elevated following weight loss secondary to bariatric surgery (2013) (0)
- prereceptor amplification of glucocorticoid Cell-intrinsic regulation of murine dendritic cell function and survival by (2014) (0)
- Predictors of response to medical therapy in patients with acromegaly (2008) (0)
- Abnormal cortisol metabolism in growth hormone deficient adults; the role of hydrocortisone replacement therapy and effect on body composition (2009) (0)
- Monogenic polycystic ovary syndrome (PCOS) due to novel mutations in the H6PD gene - apparent cortisone reductase deficiency (ACRD) (2007) (0)
- Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS (2023) (0)
- Urinary glucocorticoid metabolite excretion is associated with insulin resistance independent of body mass index (BMI) in patients with polycystic ovary syndrome (2012) (0)
- REDUCED EXPRESSION OF 11BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 2 IN KIDNEY BIOPSIES OF PATIENTS WITH RENAL FAILURE (2003) (0)
- Expression and corticosteroid regulation of serum and glucocorticoid regulated kinase, and epithelial sodium channel subunits in human ocular ciliary epithelium (2002) (0)
- Expression of mineralocorticoid effector mechanisms in renal biopsies of patients with severe proteinuria (2004) (0)
- Progesterone inactivation in human osteoblasts (2005) (0)
- Cytokine profiles in idiopathic intracranial hypertension (2008) (0)
- The ever changing facets of Cushing's syndrome (2016) (0)
- Characterising the role of 11[beta]-hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) in viral meningitis (2010) (0)
- Part 4 Parathyroid, calcium, and bone metabolism (2011) (0)
- 3.5 Thyroid lumps (2011) (0)
- Systolic Blood Pressure Increases with Time in Obese Patients and Is Predicted By Adipose Expression of the Mineralocorticoid Receptor Gene (2014) (0)
- Part 8 Female endocrinology and pregnancy (2011) (0)
- Perioperative Glycemic Control in Post-Cardiac Surgery Patients (2016) (0)
- 11 beta-hydroxysteroid dehydrogenase type 1 in obese children (2007) (0)
- Exacerbated hepatic inflammatory response to diet-induced non-alcoholic fatty liver disease in 1 male 11β-HSD1 knockout mice 2 (2016) (0)
- 7.2 Growth and sexual disorders in childhood (2011) (0)
- 13.5 Microvascular complications (2011) (0)
- 13.2 Aetiology and pathogenesis of type 1 diabetes mellitus (2011) (0)
- Muscle cell differentiation is regulated by glucocorticoids, a process which is potentiated through the induction of 11 beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) (2007) (0)
- A rabbit model for evaluating corticosteroid metabolism in ocular and orbital tissues (2004) (0)
- The medical treatment of adrenal disease. (1989) (0)
- MicroRNA: a novel post transcriptional regulator of 11[beta]-hydroxlase (CYP11B1) and aldosterone synthase (CYP11B2) (2009) (0)
- Section Introduction: Emergent Management of Adrenal Disorders (2014) (0)
- Grand Rounds—Queen Elizabeth Medical Centre, Birmingham: Systemic lupus erythematosus (1997) (0)
- Glucocorticoid metabolism in human obesity; increased 5[alpha]-reductase activity is associated with insulin resistance in both men and women (2008) (0)
- 11.1 Secondary endocrine tumours, ectopic hormone syndromes, and effects of cancer treatment on endocrine function (2011) (0)
- TNF a -mediated Hsd11b1 binding of NF- k B p65 is associated with suppression of 11 b -HSD1 in muscle (2014) (0)
- Adverse outcome in glucocorticoid induced adrenal suppression; an analysis of short synacthen tests in 2782 patients (2014) (0)
- Analysis of novel mutations in the HSD11B2 gene: Implications for AME and possibly IUGR (2002) (0)
- Safety And Efficacy Of Converting Patients With Acromegaly From Long-Acting Octreotide To Pegvisomant (2003) (0)
- Differential regulation of the ghrelin promoter in WRL68 and HEK293 cells (2003) (0)
- Cerebrospinal fluid and a novel cortisol generating system in the choroid plexus (2007) (0)
- CYP27b and CYP24 expression combine to determine 1,25 Dihydroxyvitamin D3 insensitivity in breast cancer cells (2003) (0)
- Effect of ACTH deficiency and hydrocortisone replacement dose on mortality in patients with acromegaly (2009) (0)
- Chapter 11 Enzyme modulation of access to corticosteroid receptors (1997) (0)
- Glucocorticoid activation in muscle by 11[beta]-hydroxysteroid dehydrogenase type 1: contributions to inflammatory muscle wasting (2014) (0)
- Phenotypic variability in P450 oxidoreductase deficiency may be caused by differential effects of P450 oxidoreductase mutations on steroidogenesis (2006) (0)
- Mutagenesis studies on recombinant human 11beta-hydroxysteroid dehydrogenase type 1 (2003) (0)
- Disorders of the adrenal cortex (2010) (0)
- 13.6 Macrovascular diseases and diabetes mellitus (2011) (0)
- 20. An abnormality in cortisol metabolism in patients with renal disease (1988) (0)
- 11 beta-Hydroxysteroid dehydrogenase. (1994) (0)
- Steroid metabolomics in adrenocortical carcinoma reveals mitotane as an inducer of CYP3A4 and an inhibitor of 5alpha-reductase activity with major implications for drug metabolism and hydrocortisone replacement (2012) (0)
- Longitudinal changes in adipose tissue gene expression profile are asociated with deteriorating glucose tolerance (2015) (0)
- AutocrineMetabolism ofVitamin D in Normal andMalignant (2005) (0)
- Identification and functional impact of novel mutations in the gene encoding 11[beta]-hydroxysteroid dehydrogenase type 1 in patients with hyperandrogenism (2010) (0)
- Aging Determines the Expression of Key Regulatory Gene Clusters in Human Adipose Tissue (2014) (0)
- A defect in the DHEA-DHEAS shuttle defines a novel cause of polycystic ovary syndrome (2005) (0)
- 10.2 Endocrinology of systemic disease (2011) (0)
- 10.1 Ageing and the endocrine system (2011) (0)
- Adipose tissue lipid homeostasis in mice lacking hexose-6-phosphate dehydrogenase (2008) (0)
- 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) expression is impaired in kidney biopsies from patients with renal failure (2004) (0)
- Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status (2014) (0)
- Effect of radiotherapy and pituitary dysfunction on mortality in patients with acromegaly (2008) (0)
- The impact of endogenous cortisone on bone and fat: demonstration of in vivo 11beta-hydroxysteroid dehydrogenase type 1 activity (2004) (0)
- Effects of glucocorticoids on wnt expression in synovial fibroblasts: potential role in inflammatory bone loss (2010) (0)
- Cortisol, DHEA and DHEAS in severe sepsis - a paradigm revisited (2005) (0)
- Defining and exploring the excessive healthcare burden of adrenal insufficiency (2015) (0)
- Part 11 Endocrinology of Cancer: Endocrinology and Diabetes Second Edition (2011) (0)
- Aberrant local steroid metabolism and its modulation by intravenous salbutamol in patients with acute respiratory distress syndrome (2007) (0)
- Growth hormone deficiency in adults: the NICE criteria do not discriminate an adverse cardiovascular phenotype (2009) (0)
- Negative regulation of 11[beta]-HSD1 by GH in key metabolic tissues may contribute to metabolic disease in GH deficient patients (2012) (0)
- Real World Mortality and Specific Causes of Death in Chronic Oral Glucocorticoid Use: A Systematic Review, Meta-Analysis and Meta-Regression (2021) (0)
- Longitudinal changes in glucocorticoid metabolism predict the development of metabolic phenotype (2014) (0)
- Urinary steroid profiling as a biomarker tool for the detection of adrenal malignancy: results of the EURINE ACC Study (2009) (0)
- 3.2 Aetiology of thyroid disorders (2011) (0)
- Autocrine generation of androgens within adipose tissue: Implications for polycystic ovarian syndrome (PCOS) (2002) (0)
- The local and sytemic effects of glucocorticoid generation in synovium (2008) (0)
- 2.6 Neuropsychiatric endocrinological disorders (2011) (0)
- Expression of adipose 11 beta-hydroxysteroid dehydrogenase type 1 in human obesity (2002) (0)
- Part 7 Growth and development during childhood (2011) (0)
- 12.2 Lipoprotein metabolism and related diseases (2011) (0)
- Lessons from Appenberg: 11 beta-hydroxysteroid dehydrogenase 1B or 2? (1994) (0)
- DHEA but not DHEAS exerts anti-glucocorticoid action in human preadipocytes (2007) (0)
- 11[beta]-HSD1-mediated decrease in COX2 expression is abrogated by hypoxia in human dermal fibroblasts (2015) (0)
- 9.2 Normal male endocrinology (2011) (0)
- Expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 are increased following weight loss (2003) (0)
- Glucocorticoid and insulin regulation of lipogenesis in human adipose tissue (2009) (0)
- A model for evaluating 11beta-hydroxysteroid dehydrogenase type 1 activity in ocular and orbital tissues (2004) (0)
- Inhibition of 11beta-HSD2 has an anti-proliferative effect on pituitary tumour cells (2002) (0)
- Glucocorticoids, 11-β hydroxysteroid dehydrogenase and glucose metabolism (2004) (0)
- Abnormalities in lipogenesis and lipolysis in Mice Lacking Hexose-6-Phosphate Dehydrogenase (H6PDH) (2007) (0)
- Urinary Glucocorticoid Metabolite Excretion is Associated with Insulin Resistance Independent of BMI in Patients with Polycystic Ovary Syndrome (2012) (0)
- Pituitary Disease (2002) (0)
- Comment on: Monitoring the response to treatment in acromegaly. Author's reply (2005) (0)
- Textbook of Hypertension (1995) (0)
- A serum microRNA profile potentially associated with glucocorticoid mediated insulin resistance (2013) (0)
- TNF a-mediated Hsd 11 b 1 binding of NFk B p 65 is associated with suppression of 11 b-HSD 1 in muscle (2014) (0)
- TRB3: A mechanism for glucocorticoid induced insulin sensitisation in human adipocytes (2007) (0)
- Androgenemic Phenotype Predicts Metabolic Disease and Androgen Burden in Polycystic Ovary Syndrome (2013) (0)
- From bench to bedside and beyond: a novel therapy to improve wound healing in type 2 diabetes (2019) (0)
- 12.3 Other metabolic disorders (2011) (0)
- Increased 5alpha-reductase activity during the luteal phase of the normal menstrual cycle (2005) (0)
- 13.4.3 Diabetes in diverse ethnic groups (2011) (0)
- 11Beta-hydroxysteroid dehydrogenase in human fibroblasts: Expression and regulation depends on tissue of origin (2003) (0)
- 12.1 Epidemiology, aetiology, and management of obesity (2011) (0)
- Characterisation of Pre–Teceptor Glucocorticoid Regulation in the Rabbit Eye (2006) (0)
- Growth hormone (GH) deficiency in adults treated for acute lymphoblastic leukaemia (ALL) in childhood (2002) (0)
- Adrenal Insufficiency Due to Prescribed Glucocorticoids Is Associated with Adverse Outcome: An Analysis of 3666 ACTH Stimulation Tests (2014) (0)
- Prospective changes in glucocorticoid metabolism predict alterations in metabolic phenotype (2010) (0)
- 3.1 Evaluation of the thyroid patient (2011) (0)
- Pathophysiology and genetics of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency (2005) (0)
- A paracrine role for 11[beta]-hydroxysteroid dehydrogenase type 1 and glucocorticoids in the murine pancreatic islet (2008) (0)
- Lack of 11[beta]-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing's syndrome (2014) (0)
- The prevalence and morbidity of long-term oral corticosteroid therapy (2002) (0)
- 9.4 Male endocrinological disorders and male factor infertility (2011) (0)
- Are alcoholic liver disease and fatty liver consequences of an abnormal hepatic steroid metabolism (1998) (0)
- EVALUATION OF URINARY FREE CORTISOL/CORTISONE RATIO IN SALT RESISTANT AND SALT SENSITIVE HYPERTENSION: P2.124 (2000) (0)
- 13.3 Aetiology and pathogenesis of type 2 diabetes mellitus (2011) (0)
- El aldosteronismo primario (2007) (0)
- Bacterial and yeast co-expression studies reveal hexose-6-phosphate dehydrogenase to be a crucial regulator of 11beta-hydroxysteroid dehydrogenase type 1 oxoreductase activity (2004) (0)
- Accelerated Progression to Steatohepatitis in 11(a)over-cap-Hydroxysteroid Dehydrogenase Type 1 Knockout Mice Fed a Steatogenic Diet (2014) (0)
- Reduced cortisol metabolism during critical illness. (2013) (0)
- 11[beta]-hydroxysteroid dehydrogenase type 1 mediates anti-inflammatory, pro-inflammatory and inflammation-independent effects in primary human dermal fibroblasts (2016) (0)
- The Systemic 'Spill-over' of sFRP2 in Obesity (2014) (0)
- Glucocorticoids increase subcutaneous adipose tissue insulin sensitivity in vivo: a randomised double-blind, placebo controlled, cross over study (2012) (0)
- Synergistic induction of osteoblastic local glucocorticoid metabolism by inflammatory cytokines and glucocorticoids: a novel mechanism for glucocorticoid-induced bone disease (2006) (0)
- Aqueous Humour Immunosuppressive Components Do Not Regulate Lipopolysaccharide Mediation of Autocrine Cortisol Bioavailability in Macrophage Subsets (2008) (0)
- Changes in adipose tissue gene expression profile and fat mass are associated with deteriorating glucose tolerance (2016) (0)
- Outcomes in acromegaly: A retrospective study of 419 patients from the West Midlands region of the United Kingdom (2003) (0)
- Enhanced hypothalamic-pituitary-adrenal axis activation, 5[alpha]-reductase activity and insulin resistance distinguishes polycystic ovary syndrome from simple obesity (2008) (0)
- Identification of glucocorticoid target genes in human subcutaneous and omental adipose tissue using microarray analysis (2003) (0)
- CYP24 action: An intrinsic mechanism of resistance in breast and prostate cancer cells (2002) (0)
- Weight loss is associated with reduced glucocorticoid production, decreased 5[alpha]-reductase activity and enhanced adipose tissue insulin sensitivity (2008) (0)
- Hypopituitarism after Adult Acute Lymphoblastic Leukaemia (1998) (0)
- MON-189 Evaluation of Adrenal Insufficiency and Recovery in Rheumatology Patients on Long-Term Glucocorticoid Therapy (2020) (0)
- The role of serum and urinary steroids in the monitoring of adults with congenital adrenal hyperplasia (2009) (0)
- Upregulation of mineralocorticoid receptor (MR) and sgk1 mRNA expression is associated with increased inflammatory markers [macrophage chemoattractant protein 1 (MCP1), transforming growth factor beta1 (TGF-beta1), interleukin-6 (IL-6)] in renal biopsies of patients with severe proteinuria (2005) (0)
- 2.4 Aetiology, pathogenesis, and management of diseases of the hypothalamus (2011) (0)
- Urinary steroid profiling demonstrates induction of CYP3A4 and inhibition of 5alpha-reductase by mitotane treatment for adrenocortical carcinoma (2012) (0)
- Bioinformatic analysis of altered microRNA production in normal adrenal tissue and aldosterone-producing adenoma (2014) (0)
- Increased 11[beta]-hydroxysteroid dehydrogenase type 1 activity is associated with the adverse expression of glucocorticoid target genes in ageing human skin (2012) (0)
- Immunohistochemical localisation of 11β-hydroxysteroid dehydrogenase type 1 in murine pancreatic islets (2007) (0)
- Selective inhibition of 11[beta]-hydroxysteroid dehydrogenase type 1 improves insulin sensitivity in skeletal muscle through modulation of IRS1 serine phosphorylation (2009) (0)
- Reduced 5α-reductase activity in peripheral blood mononuclear cells in polycystic ovarian syndrome a compensatory mechanism for androgen excess? (2007) (0)
- 11.2 Hormonal therapy for breast and prostatic cancers (2011) (0)
- 7.1 Normal growth and sexual development (2011) (0)
- Activation of the unfolded protein response pathway in the skeletal muscle of hexose-6-phosphate dehydrogenase knockout mice induces a severe myopathy (2008) (0)
- Glucocorticoid regulation of 11[beta]-hydroxysteroid dehydrogenase type 1 in dermal fibroblasts (2009) (0)
- Increased morbidity and hospital admissions in patients with adrenal insufficiency (2016) (0)
- MON-447 Impact Of Cortisone And Glucocorticoid Metabolites On Bone Turnover Markers in Male Patients With Hypopituitarism (2019) (0)
- 11[beta]-HSD1 is a regulator of brown adipose tissue function and mediates stress adaptation in glucocorticoid excess (2016) (0)
- Mutations in the HSD11B2 gene causing AME in the Oman population (2003) (0)
- Debate: This house believes that all adrenal patients with incidentalomas who fail to suppress after dexamethasone should have an adrenalectomy (2012) (0)
- The urinary cortisol metabolome in patients with adrenal insufficiency: Dual-release hydrocortisone is less deleterious than conventional hydrocortisone therapy (2018) (0)
- Divergent Roles of IGF-1 and Tnfα upon Human Preadipocyte Differentiation and Cortisol Metabolism (2001) (0)
- Premature mortality and hypopituitarism - Authors' reply (2001) (0)
- Inhibitors of CYP 3 A 4 Activity CYP 3 A 4 Inhibitors Antifungals Fluconazole Itraconazole Ketoconazole Macrolides Clarithromycin Erythromycin Calcium channel blockers Verapamil Diltiazem (2014) (0)
- 11β-HSD1 contributes to age-related metabolic decline in male mice (2022) (0)
- Non alcoholic fatty liver disease is associated with increased 5[alpha]-reductase expression and activity and consequent HPA-axis activation (2009) (0)
- Part 5 The adrenal gland and endocrine hypertension (2011) (0)
- The Role of Cortisol Metabolism in the Pathogenesis of Central Obesity (2002) (0)
- Inactivating progesterone metabolism in human osteoblasts (2004) (0)
- Dehydroepiandrosterone exerts anti-glucocorticoid action on proliferation, differentiation and insulin sensitivity in human preadipocytes (2008) (0)
- Pegvisomant : a novel approach to the treatment of acromegaly (2003) (0)
- Glucocorticoid and insulin regulation of lipid metabolism in human adipocytes (2010) (0)
- Glucocorticoid-induced lipolysis across human ageing and the relationship to fat mass and androgens (2015) (0)
- The Immunological Roles of Toll-Like Receptors and Glucocorticoids in Corneal Cells (2009) (0)
- 11beta-hydroxysteroid dehydrogenase type 1 and the production of cerebrospinal fluid (2004) (0)
- Pre-receptor cortisol metabolism is a critical regulator of insulin signalling in human adipose tissue (2008) (0)
- Enhanced expression of hepatic inflammatory markers in 11[beta]-hydroxysteroid dehydrogenase type 1 knockout mice fed a steatogenic diet (2014) (0)
- 11[beta]-Hydroxysteroid dehydrogenase inhibitors for treatment of metabolic syndrome (2011) (0)
- 11β-Hydroxysteroid dehydrogenase type 1 oxo-reductase activity is increased in patients with alcoholic chronic liver disease: the key to the phenotype of the alcoholic pseudo-Cushings state? (2006) (0)
- A1.30 High 11β-HSD1 activity is associated with progression to rheumatoid arthritis in patients with early inflammatory arthritis (2014) (0)
- University of Dundee Genotype at the P554L Variant of the Hexose-6 Phosphate Dehydrogenase Gene Is Associated with Carotid Intima-Medial Thickness Rahman, (2011) (0)
- Impairment of the HPA axis after treatment with glucocorticoids (2023) (0)
- Patient information page from the hormone foundation: El aldosteronismo primario (2007) (0)
- Using a morning cortisol to predict adrenal reserve and guide management (2015) (0)
- Influence of instability of thiocyanate in argentimetry and mercurimetry (1983) (0)
- 11[beta]-hydroxysteroid dehydrogenases: common lessons from rare mutations (2009) (0)
- Apparent Mineralocorticoid Excess Syndrome : An Overview Mario Palermo (2005) (0)
- Glucose-6-phosphate disposal and regulation of 11β-hydroxysteroid Dehydrogenase type 1: A new link between cellular glucose metabolism and the HPA axis (2007) (0)
- Use of IT in diabetes Care (2010) (0)
- 13.4.10 Management of diabetes mellitus in special situations (2011) (0)
- 13.10 Transplantation in Diabetes (2011) (0)
- A hypomorphic H6PD allele is sufficient to rescue the skeletal myopathy but not the lack of 11[beta]-HSD type 1-mediated glucocorticoid regeneration phenotypes of H6PDKO mice (2012) (0)
- The impact of endogenous cortisone on bone: Demonstration of in vivo 11beta-hydroxysteroid dehydrogenase type 1 activity. (2004) (0)
- Reduced androgen activation in peripheral blood mononuclear cells in polycystic ovarian syndrome – a compensatory mechanism for hyperandrogenaemia? (2007) (0)
- GENETIC DISORDERS OF MINERALOCORTICOIDS (2003) (0)
- 11β-Hydroxysteroid dehydrogenase type 1 inhibition protects against the development of adverse metabolic and bone effects of prednisolone: A randomized, double-blind, placebo-controlled trial (2020) (0)
- P450 oxidoreductase and androgen metabolism (2006) (0)
- Hepatic mRNA expression of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) in patients with non-alcoholic steatohepatitis (NASH) (2007) (0)
- Regulation of 11[beta]-hydroxysteroid dehydrogenase type 1 activity in myocytes by differentiation stage, GH/IGF1 and glucocorticoids (2009) (0)
- Defining the molecular basis for apparent cortisone reductase deficiency reveals a novel redox potential mechanism within the endoplasmic reticulum (2003) (0)
- Development of urinary steroid profiling as a high-throughput screening tool for the detection of malignancy in patients with adrenal tumours (2010) (0)
- Supplemental material of manuscript entitled: Dose-response and evidence of underdiagnoses of adrenal glucocorticoid adverse events: findings from a population based cohort in England (2019) (0)
- High 11[beta]-HSD1 activity is associated with progression to rheumatoid arthritis in patients first presenting with inflammatory arthritis (2014) (0)
- In vitro expression of catalytically active human aldosterone synthase (2002) (0)
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