Harry Schachter | Academic Influence

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Harry Schachter

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Artificial Intelligence

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Computer Science

Harry Schachter's Degrees

PhD Computer Science Stanford University
Masters Computer Science Stanford University
Bachelors Computer Science Stanford University

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Why Is Harry Schachter Influential?

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According to Wikipedia, Harry Schachter FRSC is a Canadian biochemist and glycobiologist, and professor emeritus at the University of Toronto and the Hospital For Sick Children in Toronto, Canada. Biography Harry Schachter was born in Vienna, Austria in 1933, to Miriam Freund, a businesswoman, and to Ulrich Schachter, a dentist and medical doctor. Harry's father was the cousin of Austro-Hungarian and Romanian tenor and actor, Joseph Schmidt. The Schachter family fled the Nazis in 1938, escaping to Port of Spain, Trinidad. He attended secondary school at Saint Mary's College, placing first in Trinidad in the Cambridge Advanced Level Examinations, and winning the Jerningham Gold Medal and the Island Scholarship in Mathematics. He also worked part-time as a reporter for the local Guardian newspaper. His family immigrated to Toronto, Canada in 1951.

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Harry Schachter's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. (1997) (1089)
Intracellular localization of liver sugar nucleotide glycoprotein glycosyltransferases in a Golgi-rich fraction. (1970) (498)
Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides. (1986) (376)
Complex asparagine‐linked oligosaccharides are required for morphogenic events during post‐implantation development. (1994) (325)
O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding (2010) (323)
O-GalNAc Glycans (2009) (270)
LARGE can functionally bypass α-dystroglycan glycosylation defects in distinct congenital muscular dystrophies (2004) (262)
X‐ray crystal structure of rabbit N‐acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily (2000) (261)
Control of glycoprotein synthesis. (1983) (243)
Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides. (1986) (222)
ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome (2012) (216)
Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity. (1975) (191)
The 'yellow brick road' to branched complex N-glycans. (1991) (190)
Carbohydrate deficient glycoprotein syndrome type II: a deficiency in Golgi localised N-acetyl-glucosaminyltransferase II. (1994) (178)
A structural basis for four distinct elution profiles on concanavalin A--Sepharose affinity chromatography of glycopeptides. (1979) (165)
Product-identification and substrate-specificity studies of the GDP-l-fucose: 2-acetamido-2-deoxy-β-d-glucoside (fuc→asn-linked GlcNAc) 6-α-l-fucosyltransferase in a golgi-rich fraction from porcine liver☆ (1982) (150)
Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development. (1996) (149)
Control of glycoprotein synthesis. Processing of asparagine-linked oligosaccharides by one or more rat liver Golgi alpha-D-mannosidases dependent on the prior action of UDP-N-acetylglucosamine: alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase I. (1980) (147)
Control of branching during the biosynthesis of asparagine-linked oligosaccharides. (1983) (144)
The control of glycoprotein synthesis: N-acetylglucosamine linkage to a mannose residue as a signal for the attachment of L-fucose to the asparagine-linked N-acetylglucosamine residue of glycopeptide from alpha1-acid glycoprotein. (1976) (140)
Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. (2001) (133)
Handbook of Glycosyltransferases and Related Genes (2014) (132)
Biosynthesis of glycoprotein by liver. The incorporation in vivo of 14C-glucosamine into protein-bound hexosamine and sialic acid of rat liver subcellular fractions. (1966) (127)
Handbook of Glycosyltransferases and Related Genes (2002) (125)
Enzymic methods for the micro assay of D-mannose, D-glucose, D-galactose, and L-fucose from acid hydrolyzates of glycoproteins (1969) (124)
Qualitative differences in the N-acetyl-D-galactosaminyltransferases produced by human A1 and A2 genes. (1973) (119)
Control of glycoprotein synthesis. Lectin-resistant mutant containing only one of two distinct N-acetylglucosaminyltransferase activities present in wild type Chinese hamster ovary cells. (1977) (116)
The joys of HexNAc. The synthesis and function of N-andO-glycan branches (2000) (114)
Glycosylation diseases: quo vadis? (2009) (109)
Control of glycoprotein synthesis. Purification and characterization of rabbit liver UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. (1988) (102)
Structural requirements for Arabidopsis beta1,2-xylosyltransferase activity and targeting to the Golgi. (2003) (99)
A quantitative difference in the activity of blood group A-specific N-acetylgalactosaminyltransferase in serum from A 1 and A 2 human subjects. (1971) (97)
Sialic acids. 13. A uridine diphosphate D-galactose: mucin galactosyltransferase from porcine submaxillary gland. (1971) (97)
Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa. (1985) (96)
Control of glycoprotein synthesis. The use of oligosaccharide substrates and HPLC to study the sequential pathway for N-acetylglucosaminyltransferases I, II, III, IV, V, and VI in the biosynthesis of highly branched N-glycans by hen oviduct membranes. (1988) (93)
Control of glycoprotein synthesis. Kinetic mechanism, substrate specificity, and inhibition characteristics of UDP-N-acetylglucosamine:alpha-D-mannoside beta 1-2 N-acetylglucosaminyltransferase II from rat liver. (1987) (93)
Carbohydrate-deficient glycoprotein syndromes become congenital disorders of glycosylation: An updated nomenclature for CDG (1999) (93)
Biosynthesis of mucus glycoproteins. (1982) (92)
Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. (1991) (92)
Null Mutations in Drosophila N-Acetylglucosaminyltransferase I Produce Defects in Locomotion and a Reduced Life Span* (2006) (90)
Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid. (1988) (90)
Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction. (1997) (90)
Control of glycoprotein synthesis. Bovine colostrum UDP-N-acetylglucosamine:alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase I. Separation from UDP-N-acetylglucosamine:alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase II, partial purification, and substrate specificity. (1980) (89)
Biosynthesis of O-glycans in leukocytes from normal donors and from patients with leukemia: increase in O-glycan core 2 UDP-GlcNAc:Gal beta 3 GalNAc alpha-R (GlcNAc to GalNAc) beta(1-6)-N-acetylglucosaminyltransferase in leukemic cells. (1991) (87)
Walker-Warburg syndrome (2006) (85)
The biosynthesis of highly branched N-glycans: studies on the sequential pathway and functional role of N-acetylglucosaminyltransferases I, II, III, IV, V and VI. (1988) (85)
Glycoproteins and disease (1996) (84)
Glycoproteins: their structure, biosynthesis and possible clinical implications. (1984) (83)
Mild POMGnT1 mutations underlie a novel limb-girdle muscular dystrophy variant. (2008) (81)
Congenital disorders involving defective N-glycosylation of proteins (2001) (81)
The transmembrane and flanking sequences of beta 1,2-N-acetylglucosaminyltransferase I specify medial-Golgi localization. (1992) (81)
Expression of Three Caenorhabditis elegans N-Acetylglucosaminyltransferase I Genes during Development* (1999) (74)
The effect of a "bisecting" N-acetylglucosaminyl group on the binding of biantennary, complex oligosaccharides to concanavalin A, Phaseolus vulgaris erythroagglutinin (E-PHA), and Ricinus communis agglutinin (RCA-120) immobilized on agarose. (1986) (72)
The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein. (1995) (70)
Control of glycoprotein synthesis. Purification of UDP-N-acetylglucosamine:alpha-D-mannoside beta 1-2 N-acetylglucosaminyltransferase II from rat liver. (1987) (70)
Branch specificity of purified rat liver Golgi UDP-galactose: N-acetylglucosamine beta-1,4-galactosyltransferase. Preferential transfer of of galactose on the GlcNAc beta 1,2-Man alpha 1,3-branch of a complex biantennary Asn-linked oligosaccharide. (1984) (68)
Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver. (1969) (67)
Porcine sugar nucleotide: glycoprotein glycosyltransferases. II. Blood serum and liver galactosyltransferase. (1971) (66)
Genetic Disorders of Glycosylation (2009) (65)
Glycosyltransferases Involved in N–and O–Glycan Biosynthesis (1996) (65)
Control of glycoprotein synthesis. The purification by preparative high voltage paper electrophoresis in borate of glycopeptides containing high mannose and complex oligosaccharide chains linked to asparagine. (1980) (65)
Mucin synthesis. I. Detection in canine submaxillary glands of an N-acetylglucosaminyltransferase which acts on mucin substrates. (1980) (63)
Intracellular localization of GDP-L-fucose:glycoprotein and CMP-sialic acid: apolipoprotein glycosyltransferases in rat and pork livers. (1975) (63)
Asparagine-linked oligosaccharides in murine tumor cells: comparison of a WGA-resistant (WGAr) nonmetastatic mutant and a related WGA-sensitive (WGAs) metastatic line (1984) (63)
The presence of two GDP-L-fucose: glycoproteine fucosyltransferases in human serum. (1973) (62)
Partial characterization of a novel glycerogalactolipid from rat testis. (1972) (58)
Mucin synthesis. Conversion of R1-beta 1-3Gal-R2 to R1-beta 1-3(GlcNAc beta 1-6)Gal-R2 and of R1-beta 1-3GalNAc-R2 to R1-beta 1-3(GlcNAc beta 1-6)GalNAc-R2 by a beta 6-N-acetylglucosaminyltransferase in pig gastric mucosa. (1986) (57)
Pork liver guanosine diphosphate-L-fucose glycoprotein fucosyltransferases. (1971) (57)
Protein glycosylation lessons from Caenorhabditis elegans. (2004) (56)
Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D- glucosamine:α-3-D-mannoside β1,2-N-acetylglucosaminyltransferase I (2004) (55)
Control of glycoprotein synthesis. Detection and characterization of a novel branching enzyme from hen oviduct, UDP-N-acetylglucosamine:GlcNAc beta 1-6 (GlcNAc beta 1-2)Man alpha-R (GlcNAc to Man) beta-4-N-acetylglucosaminyltransferase VI. (1989) (55)
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. (2008) (55)
Cloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I (2002) (54)
The human UDP‐N‐Acetylglucosamine:α‐6‐d‐Mannoside‐β‐1,2‐N‐Acetylglucosaminyltransferase II Gene (MGAT2) (1995) (54)
The levels of nucleotide-sugar: glycoprotein sialyl- and N-acetylglucosaminyltransferases in normal and pathological human sera. (1972) (53)
The biosynthesis of branched O-glycans. (1989) (53)
Studies on the structure and formation during spermatogenesis of the sulfoglycerogalactolipid of rat testis. (1974) (51)
Control of glycoprotein synthesis. Bovine milk UDPgalactose:N-acetylglucosamine beta-4-galactosyltransferase catalyzes the preferential transfer of galactose to the GlcNAc beta 1,2Man alpha 1,3- branch of both bisected and nonbisected complex biantennary asparagine-linked oligosaccharides. (1985) (51)
THE BIOSYNTHESIS OF ANIMAL GLYCOPROTEINS (1973) (51)
Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylglucosaminidase. (2003) (49)
Enzymatic diagnostic test for Muscle-Eye-Brain type congenital muscular dystrophy using commercially available reagents. (2003) (49)
Molecular Cloning and Expression of cDNA Encoding the Rat UDP-N-Acetylglucosamine:α-6-D-Mannoside β-1,2-N-Acetylglucosaminyltransferase II (*) (1995) (48)
Mucin synthesis. II. Substrate specificity and product identification studies on canine submaxillary gland UDP-GlcNAc:Gal beta 1-3GalNAc(GlcNAc leads to GalNAc) beta 6-N-acetylglucosaminyltransferase. (1980) (48)
Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine: α-3-D-mannoside β-1,2-N-acetylglucosaminyltransferase I gene+ (1991) (47)
The inhibition of rat liver polyribosome breakdown in the presence of liver supernatant. (1966) (47)
Enzymes associated with glycosylation (1991) (47)
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. (2002) (47)
Cloning and Expression of Drosophila melanogaster UDP-GlcNAc:?-3-D-Mannoside ? 1,2-N-Acetylglucosaminyltransferase I (2001) (47)
Expression of stable human O-glycan core 2 beta-1,6-N-acetylglucosaminyltransferase in Sf9 insect cells. (1997) (46)
The subcellular sites of glycosylation. (1974) (45)
Mucin synthesis. III. UDP-GlcNAc:Galβ1-3(GlcNAcβ1-6)GalNAc-R (GlcNAc to Gal) β3-N-acetylglucosaminyltransferase, an enzyme in porcine gastric mucosa involved in the elongation of mucin-type oligosaccharides (1983) (45)
Paucimannose N-glycans in Caenorhabditis elegans and Drosophila melanogaster. (2009) (45)
A method for proteomic identification of membrane-bound proteins containing Asn-linked oligosaccharides. (2004) (43)
Control of glycoprotein synthesis. IX. A terminal Man alpha l-3Man beta 1- sequence in the substrate is the minimum requirement for UDP-N-acetyl-D-glucosamine: alpha-D-mannoside (GlcNAc to Man alpha 1-3) beta 2-N-acetylglucosaminyltransferase I. (1984) (43)
GDP-fucose: β-N-acetylglucosamine (Fuc to (Fucα1 → 6GlcNAc)-Asn-peptide) α1 → 3-fucosyltransferase activity in honeybee (Apis mellifica) venom glands (1991) (42)
High-performance liquid chromatography assays for N-acetylglucosaminyltransferases involved in N- and O-glycan synthesis. (1989) (42)
Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa. (2002) (42)
The Structure and Biosynthesis of Membrane Glycoproteins (1978) (41)
The effect of turpentine-induced inflammation on rat liver glycosyltransferases and Golgi complex ultrastructure. (1980) (41)
PREFERENTIAL OXIDATION OF THE METHIONINE RESIDUE NEAR THE ACTIVE SITE OF CHYMOTRYPSIN. (1964) (41)
Coordination between enzyme specificity and intracellular compartmentation in the control of protein‐bound oligosaccharide biosynthesis (1984) (40)
Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type. (1983) (39)
Evidence for two CMP-N-acetylneuraminic acid: lactose sialyltransferases in rat, porcine, bovine, and human liver. (1972) (38)
Identification of the hydrophobic glycoproteins of Caenorhabditis elegans. (2005) (38)
Glycoprotein glycosyltransferase levels during spermatogenesis in mice. (1974) (38)
Suppression of Cancer Progression by MGAT1 shRNA Knockdown (2012) (37)
N-glycans are involved in the response of Caenorhabditis elegans to bacterial pathogens. (2006) (37)
Mgat1-dependent N-glycans are essential for the normal development of both vertebrate and invertebrate metazoans. (2010) (36)
Chapter 5 Biosynthesis 2c. Glycosyltransferases Involved in the Synthesis of N-Glycan Antennae (1995) (36)
Removal of 106 amino acids from the N-terminus of UDP-GlcNAc :alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I does not inactivate the enzyme (1998) (36)
Control of glycoprotein synthesis. The in vitro synthesis by hen oviduct membrane preparations of hybrid asparagine-linked oligosaccharides containing 5 mannose residues. (1984) (35)
UDP-N-acetylglucosamine:α-3-d-mannoside β-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:α-6-d-mannoside β-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans (2002) (35)
Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis. (1997) (35)
Structure of the glycopeptides of a human gamma 1-immunoglobulin G (Tem) myeloma protein as determined by 360-megahertz nuclear magnetic resonance spectroscopy. (1982) (34)
Identification of a novel UDP-GalNAc:GlcNAc beta-R beta 1-4 N-acetylgalactosaminyltransferase from the albumen gland and connective tissue of the snail Lymnaea stagnalis. (1995) (34)
The role of defective glycosylation in congenital muscular dystrophy (2003) (34)
L-Fucose metabolism in mammals. The conversion of L-fucose to two moles of L-lactate, of L-galactose to L-lactate and glycerate, and of D-arabinose to L-lactate and glycollate. (1979) (33)
The use of nucleotide-sugar: glycoprotein glycosyltransferases to assess Golgi apparatus function in Morris hepatomas. (1971) (32)
Use of a ribonuclease inhibitor from rat liver supernatant fraction in the preparation of polyribosome-like particles from isolated rat liver nuclei (1967) (31)
In the Biosynthesis of N-Glycans in Connective Tissue of the Snail Lymnaea Stagnalis of Incorporation GlcNAc by β2GlcNAc-transferase I is an essential prerequisite for the action of β2GlcNAc-transferase II and β2Xyl-transferase (1995) (30)
The preparation of rabbit antiserum specific for mammalian testicular sulfogalactoglycerolipid. (1980) (30)
Functional post-translational proteomics approach to study the role of N-glycans in the development of Caenorhabditis elegans. (2002) (30)
Neuronal expression of Mgat1 rescues the shortened life span of Drosophila Mgat11 null mutants and increases life span (2010) (28)
Studies on the biosynthesis of testicular sulfoglycerogalactolipid: demonstration of a Golgi-associated sulfotransferase activity. (1973) (27)
Localization of glycoprotein glycosyltransferases in the golgi apparatus of rat and mouse testis. (1974) (27)
Enzymic microassays for D-mannose, D-glucose, D-galactose, L-fucose, and D-glucosamine. (1975) (26)
Carbohydrate-deficient glycoprotein syndrome type II. An autosomal recessive N-acetylglucosaminyltransferase II deficiency different from typical hereditary erythroblastic multinuclearity, with a positive acidified-serum lysis test (HEMPAS). (1995) (26)
Insertion intoAspergillus nidulans of functional UDP-GlcNAc: α3-d-mannoside β-1,2-N-acetylglucosaminyltransferase I, the enzyme catalysing the first committed step from oligomannose to hybrid and complex N-glycans (1995) (25)
Control of glycoprotein synthesis. Characterization of (1 → 4)-N-acetyl-β-d-glucosaminyltransferases acting on the α-d-(1 → 3)- and α-d-(1 → 6)-linked arms of N-linked oligosaccharides☆ (1992) (25)
Synthesis of tetrasaccharide analogues of the N-glycan substrate of beta-(1-->2)-N-acetylglucosaminyltransferase II using trisaccharide precursors and recombinant beta-(1-->2)-N-acetylglucosaminyltransferase I. (1994) (25)
Glycosylation of glycoproteins during intracellular transport of secretory products. (1974) (25)
The clinical relevance of glycobiology. (2001) (25)
Late spermatocytes from immature rat testis isolation, electron microscopy, lectin agglutinability and capacity for glycoprotein and sulfogalactoglycerolipid biosynthesis (1978) (24)
Synthetic substrate analogues for UDP-GlcNAc: Manα1-6R β(1-2)-N-acetylglucosaminyltransferase II. Substrate specificity and inhibitors for the enzyme (1994) (24)
Carriers and patients with muscle–eye–brain disease can be rapidly diagnosed by enzymatic analysis of fibroblasts and lymphoblasts (2006) (24)
Tissue distribution of sulfolipids in the rat. Restricted location of sulfatoxygalactosylacylalkylglycerol. (1981) (24)
Product-identification and substrate-specificity studies of the GDP-L-fucose:2-acetamido-2-deoxy-beta-D-glucoside (FUC goes to Asn-linked GlcNAc) 6-alpha-L-fucosyltransferase in a Golgi-rich fraction from porcine liver. (1982) (23)
Presence of cytidine 5'-monophospho-N-acetylneuraminic acid:Gal beta 1-3GalNAc-R alpha(2-3)-sialyltransferase in normal human leukocytes and increased activity of this enzyme in granulocytes from chronic myelogenous leukemia patients. (1987) (23)
β-1,4-mannosyl-glycoprotein β-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes (1988) (23)
The PCome of Caenorhabditis elegans as a prototypic model system for parasitic nematodes: identification of phosphorylcholine-substituted proteins. (2008) (22)
Localization of sulfatoxygalactosylacylalkylglycerol at the surface of rat testicular germinal cells by immunocytochemical techniques: pH dependence of a nonimmunological reaction between immunoglobulin and germinal cells (1981) (21)
Incorporation of sialic acid into sialidase-treated apolipoprotein of human, very low density lipoprotein by a pork liver sialytransferase. (1974) (21)
The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis. (1983) (20)
Mucin synthesis. The action of pig gastric mucosal UDP-GlcNAc:Gal beta 1-3(R1)GalNAc-R2 (GlcNAc to Gal) beta 3-N-acetylglucosaminyltransferase on high molecular weight substrates. (1984) (20)
The search for glycan function: fucosylation of the TGF-beta1 receptor is required for receptor activation. (2005) (20)
Enrichment of sulfogalactosylalkylacylglycerol in a plasma membrane fraction from adult rat testis. (1980) (20)
Complex N-glycans: the story of the “yellow brick road” (2013) (20)
Gene inactivation confirms the identity of enzymes involved in nematode phosphorylcholine-N-glycan synthesis. (2008) (20)
Walker-Warburg Syndrome with POMT1 mutations can be associated with cleft lip and cleft palate (2008) (19)
Identification of a novel UDP‐Gal:GalNAcβ1‐4GlcNAc‐R (1991) (19)
Oligosaccharide branching of glycoproteins: biosynthetic mechanisms and possible biological functions. (1982) (18)
2 – Glycoprotein Biosynthesis (1978) (18)
Substrate specificity and inhibition of UDP-GlcNAc:GlcNAcβ1-2Manα1-6R β1,6-N-acetylglucosaminyltransferase V using synthetic substrate analogues (1995) (17)
Regulation of expression of the human beta-1,2-N-acetylglucosaminyltransferase II gene (MGAT2) by Ets transcription factors. (2000) (17)
The incorporation of 14C-threonine and 14C-glucosamine into subcellular fractions and into bovine submaxillary mucin by slices of bovine submaxillary gland. (1967) (17)
Control of glycoprotein synthesis: substrate specificity of rat liver UDP-GlcNAc:Manα3R β2-N-acetylglucosaminyl-transferase I using synthetic substrate analogues (1992) (16)
A COMPARATIVE STUDY OF THE PROTEINS IN NORMAL MECONIUM AND IN MECONIUM FROM MECONIUM ILEUS PATIENTS. (1965) (16)
Molecular basis of glycoconjugate disease. (1999) (16)
Identification of the methionine involved in the active center of chymotrypsin. (1962) (16)
Isolation of null alleles of the Caenorhabditis elegans gly-12, gly-13 and gly-14 genes, all of which encode UDP-GlcNAc: alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I activity. (2003) (15)
Porcine sugar nucleotide: glycoprotein glycosyltransferases. 3. Blood serum and liver N-acetylglucosaminyltransferase. (1971) (15)
The role of the GlcNAcβ1,2Manα- moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine:α-3-d-mannoside β-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:α-d-mannoside β-1,2-N-acetylglucosaminyltransferase I.2 cause embryonic lethality and cong (2002) (14)
Ablation of N-acetylglucosaminyltransferases in Caenorhabditis induces expression of unusual intersected and bisected N-glycans. (2018) (14)
Expression of stable human O-glycan core 2 β1 , 6N-acetylglucosaminyltransferase in Sf 9 insect cells (1997) (14)
Glycosyltransferases Involved in the Biosynthesis of Protein-Bound Oligosaccharides of the Asparagine-N-Acetyl-D-Glucosamine and Serine(Threonine)-N-Acetyl-D-Galactosamine Types (1985) (12)
Synthesis of pentasaccharide analogues of the N-glycan substrates of N-acetylglucosaminyltransferases III, IV and V using tetrasaccharide precursors and recombinant beta-(1-->2)-N-acetylglucosaminyltransferase II. (1995) (12)
On the interpretation of Michaelis constants for transport. (1973) (11)
Chapter 16b Carbohydrate-deficient glycoprotein syndrome: Type II: an autosomal recessive disease due to mutations in the N-acetylglucosaminyltransferase II gene (1996) (11)
Glycoconjugate abnormalities in patients with congenital dyserythropoietic anaemia type I, II and III (2001) (11)
Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. (2004) (11)
Activity of UDP-GlcNAc:GlcNAcβ1→6(GlcNAcβ1→2) Manα1→R[GlcNAc to Man]β1→4N- Acetylglucosaminyltransferase VI (GnT VI) from the Ovaries ofOryzias latipes(Medaka Fish)☆☆☆ (1997) (11)
Structural and functional consequences of an N-glycosylation mutation (HEMPAS) affecting human erythrocyte membrane glycoproteins (1998) (11)
Use of synthetic oligosaccharide substrate analogs to map the active sites of N-acetylglucosaminyltransferases I and II. (2003) (11)
Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine : α-3-D-mannoside β 1 , 2N-acetylglucosaminyltransferase I , α 3 , 6-mannosidase II and a specific membrane-bound β-N-acetylglucosaminidase (2003) (11)
The Conversion of Cortisol to 11β-Hydroxyandrostenedione by Beef Adrenal Tissue11 (1974) (10)
Zhang, W. et al. Enzymatic diagnostic test for muscle-eye-brain type congenital muscular dystrophy using commercially available reagents. Clin. Biochem. 36, 339-344 (2003) (10)
STABILIZATION OF RAT LIVER POLYRIBOSOMES BY ENDOGENOUS RIBONUCLEASE INHIBITOR (1967) (10)
Structural and functional consequences of an N-glycosylation mutation (HEMPAS) affecting human erythrocyte membrane glycoproteins. (1998) (10)
L-fucose metabolism in mammals. Kinetic studies on pork liver 2-keto-3-deoxy-L-fuconate:NAD+ oxidoreductase. (1975) (10)
N-acetylglucosaminyltransferase substrates prepared from glycoproteins by hydrazinolysis of the asparagine-N-acetylglucosamine linkage. Purification and structural determination of oligosaccharides with mannose andN-acetylglucosamine at the non-reducing termini (1988) (10)
L-Fucose metabolism in mammals. I. Port liver L-fuconate hydro-lyase. (1972) (10)
O-glycosylation in plants (1995) (9)
Enzymatic synthesis of human blood group M-, N- and T-specific structures (1976) (9)
Defective glycosyltransferases are not good for your health. (1998) (9)
Transcriptional regulation of the human UDP-GlcNAc: alpha-6-D-mannoside beta-1-2-N-acetylglucosaminyltransferase II gene (MGAT2) which controls complex N-glycan synthesis (1998) (9)
Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II. (1995) (9)
Tissues of the clawed frog Xenopus laevis contain two closely related forms of UDP-GlcNAc:α3-D-mannoside β-1,2-N-acetylglucosaminyltransferase I (2001) (9)
Structure and function of the genes encoding N-acetylglucosaminyltransferases which initiate N-glycan antennae. (1997) (9)
Porcine sugar nucleotide: glycoprotein glycosyltransferases. I. Blood serum and liver sialyltransferase. (1971) (9)
L-fucose metabolism in mammals. Purification of pork liver 2-keto-3-deoxy-L-fuconate:NAD+ oxidoreductase by NAD+-Agarose affinity chromatography. (1975) (9)
Studies of 11β-hydroxylation by beef adrenal mitochondria (1976) (8)
Branching of N- and O-Glycans Biosynthetic Controls and Functions (1992) (8)
Two closely related forms of UDP-GlcNAc: α6-D-mannoside β1,2-N-acetylglucosaminyltransferase II occur in the clawed frog Xenopus laevis (2002) (7)
THE CHEMICAL MODIFICATION OF CHYMOTRYPSIN. (1964) (7)
AN ALTERATION IN THE REACTIVITY OF CHYMOTRYPSIN AND TRYPSIN TOWARDS HYDROGEN PEROXIDE IN THE PRESENCE OF SPECIFIC SUBSTRATES. (1963) (7)
Control of biochemical parameters in glycoprotein production. (1977) (7)
Life is sweet! A novel role for N-glycans in Drosophila lifespan (2011) (7)
[29] GDP-l-[14C]Fucose (1972) (7)
UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans. (2002) (7)
Molecular cloning of human and rabbit UDP-N-acetylglucosamine: α-3-D-mannoside β-1, 2-N-acetylglucosaminyltransferase I (1991) (7)
Identification of terminal N-acetylglucosamine residues of highly branched asparagine-linked oligosaccharides as immunoreactive domains of a chicken heterophile antigenic determinant. (1987) (7)
Biosynthesis and Catabolism of Glycoproteins (1978) (7)
Synthetic substrate analogues for UDP-GlcNAc: Manα1-3R β1-2-N-acetylglucosaminyltransferase I. Substrate specificity and inhibitors for the enzyme (2004) (6)
Human Blood‐Group A‐ and H‐Specified Glycosyltransferase Levels in the Sera of Newborn Infants and their Mothers (1978) (6)
Identification of a GDP-Fuc:Galβ1–3GalNAc-R (Fuc to Gal)α1–2 fucosyltransferase and a GDP-Fuc:Galβ1–4GlcNAc (Fuc to GlcNAc)α1–3 fucosyltransferase in connective tissue of the snailLymnaea stagnalis (1996) (6)
The directed migration of gonadal distal tip cells in Caenorhabditis elegans requires NGAT-1, a ß1,4-N-acetylgalactosaminyltransferase enzyme (2017) (6)
Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. (2001) (6)
Bausteine von Oligosacchariden, CX. Synthese von potentiellen Inhibitoren für die N‐Acetylglucosaminyltransferase I (1995) (6)
Molecular cloning and characterization of the mouse UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene. (1992) (6)
The role of the GlcNAc(beta)1,2Man(alpha)- moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2 cause emb (2002) (5)
Complex N-Glycans-When, Why? (2001) (5)
N-Acetylglucosaminyltransferase-II (2002) (5)
l-Fucose kinase from pig liver☆☆☆ (1972) (5)
Stimulation of rat liver microsomal UDP-N-acetylglucosamine: glycoprotein N-acetylglucosaminyltransferase by carboxymethylcysteine-ribonuclease A. (1973) (5)
Chapter 5 Biosynthesis 4b. Substrate Level Controls for N-Glycan Assembly (1995) (5)
A functional post-translational proteomics approach to study the role of N-glycans in the development of Caenorhabditis elegans (2002) (5)
3.02 – Processing of Protein-Bound N-Glycans (2007) (5)
Molecular cloning and expression analysis of a mouse UDP-GlcNAc:Gal(β1-4)Glc(NAc)-R β1,3-N-acetylglucosaminyltransferase homologous to Drosophila melanogaster Brainiac and the β1,3-galactosyltransferase family (2000) (5)
Substrate specificity and inhibition of UDP-GlcNAc:GlcNAc beta 1-2Man alpha 1-6R beta 1,6-N-acetylglucosaminyltransferase V using synthetic substrate analogues. (1995) (5)
Bausteine von Oligosacchariden, CIX. Synthese von modifizierten Oligosacchariden der N-Glycoproteine zur Untersuchung der Substratspezifität der N-Acetylglucosaminyltransferase I (1995) (5)
Synthetic substrate analogues for UDP-GlcNAc: Man alpha 1-3R beta 1-2-N-acetylglucosaminyltransferase I. Substrate specificity and inhibitors for the enzyme. (1995) (4)
4.06 – Glycobiology of Caenorhabditis elegans (2007) (4)
Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene. (1991) (4)
In the biosynthesis of N-glycans in connective tissue of the snail Lymnaea stagnalis of incorporation GlcNAc by beta 2GlcNAc-transferase I is an essential prerequisite for the action of beta 2GlcNAc-transferase II and beta 2Xyl-transferase. (1995) (4)
GDP-fucose: beta-N-acetylglucosamine (Fuc to (Fuc alpha 1----6GlcNAc)-Asn-peptide)alpha 1----3-fucosyltransferase activity in honeybee (Apis mellifica) venom glands. The difucosylation of asparagine-bound N-acetylglucosamine. (1991) (4)
Enzymatic control of oligosaccharide branching during synthesis of membrane glycoproteins (1983) (4)
Tissues of the clawed frog Xenopus laevis contain two closely related forms of UDP-GlcNAc:alpha3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. (2001) (3)
Synthese von modifizierten Tetrasacchariden als analoge Akzeptor-Inhibitoren der N-Acetylglucosaminyltransferase II (1995) (3)
BBA special issue on developmental glycobiology (2002) (3)
Deficient glycoprotein glycosylation in humans and mice (2005) (3)
Control of glycoprotein synthesis: substrate specificity of rat liver UDP-GlcNAc:Man alpha 3R beta 2-N-acetylglucosaminyltransferase I using synthetic substrate analogues. (1992) (3)
Synthesis of Modified Tetrasaccharides as Acceptor-Inhibitor Analogues of N-Acetylglucosaminyltransferase II. (1996) (3)
Oligosaccharide Conformation and the Control of Oligosaccharide Assembly (1982) (2)
Glycoprotein biosynthesis: regulation of glycosyltransferase activity (1988) (2)
Synthetic substrate analogues for UDP-GlcNAc: Man alpha 1-6R beta(1-2)-N-acetylglucosaminyltransferase II. Substrate specificity and inhibitors for the enzyme. (1994) (2)
Control of Glycoprotein Synthesis PURIFICATION OF UDP-N-ACETYLGLUCOSAMINECX-D-MANNOSIDE p 1-2 N-ACETYLGLUCOSAMINYLTRANSFERASE I 1 FROM RAT (2001) (2)
Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
Two closely related forms of UDP-GlcNAc: alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II occur in the clawed frog Xenopus laevis. (2002) (2)
Incorporation of Sialic Acid into Sialidase-Treated Apolipoprotein of Humaa Very Low Density Lipoprotein by a Pork Liver (1974) (1)
Mucin synthesis. III. UDP-GlcNAc:Gal beta 1-3(GlcNAc beta 1-6)GalNAc-R (GlcNAc to Gal) beta 3-N-acetylglucosaminyltransferase, an enzyme in porcine gastric mucosa involved in the elongation of mucin-type oligosaccharides. (1983) (1)
Qualitative Differences in the N-Acetyl-D-galactosaminyltransferases Produced by Human Al and A 2 Genes ( blood group A / serum glycosyltransferases / glycoprotein biosynthesis / milk oligosaccharides ) (1)
Control of glycoprotein synthesis. Characterization of (1-->4)-N-acetyl-beta-D-glucosaminyltransferases acting on the alpha-D-(1-->3)- and alpha-D-(1-->6)-linked arms of N-linked oligosaccharides. (1992) (1)
Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes. (1988) (1)
[Synthesis of modified tetrasaccharides as analog acceptor-inhibitors of N-acetylglucosaminyltransferase II]. (1995) (1)
The study of glycoconjugates in pathological processes. (1995) (1)
Functional metabolism: Regulation and adaptation, K.B. Storey (Ed.). Wiley-Liss, John Wiley and Sons, Inc., Hoboken, New Jersey, USA (2004), ISBN: 0-471-41090-X (pbk.: alk.paper) (2005) (1)
S2.9 Purification of recombinant UDP-GlcNAc:α3-d-mannosideβ-1,2-N-acetylglucosaminyltransferase I (GnT I) expressed in insect cells (1993) (1)
Identification of a novel UDP-Gal:GalNAc beta 1-4GlcNAc-R beta 1-3-galactosyltransferase in the connective tissue of the snail Lymnaea stagnalis. (1991) (1)
Biosynthesis of glycoproteins with special reference to N-glycosyl oligosaccharides (1982) (1)
Activity of UDP-GlcNAc:GlcNAc beta 1-->6(GlcNAc beta 1-->2) Man alpha 1-->R[GlcNAc to Man] beta 1-->4N-acetylglucosaminyltransferase VI (GnT VI) from the ovaries of Oryzias latipes (Medaka fish). (1997) (1)
O.1 Novel O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding: implications for congenital muscular dystrophy (2010) (1)
2-Keto-3-deoxy-L-fuconate dehydrogenase from pork liver. (1982) (0)
Molecular cloning of human and rabbit UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. (1991) (0)
CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I (2001) (0)
VERKEHRSSICHERHEITSARBEIT - MEHR AUFKLAERUNG ODER HAERTERE STRAFEN ? (1982) (0)
Biomembranes. Part L: Membrane biogenesis: processing and recycling. (1983) (0)
Synthesis of Pentasaccharide Analogues of the N‐Glycan Substrates of N‐ Acetylglucosaminyltransferases III, IV, and V Using Tetrasaccharide Precursors and Recombinant β‐(1 → 2)‐N‐ Acetylglucosaminyltransferase II. (1996) (0)
The conversion of cortisol to 11beta-hydroxyandrostenedione by beef adrenal tissue. (1974) (0)
Walter Thomas James Morgan: 1900–2003 (2003) (0)
D.I.4 Patient fibroblast functional complementation studies: A valuable tool in the identification of novel Walker–Warburg syndrome disease genes (2012) (0)
Congenital disorders of N-glycosylation (2012) (0)
Obituary: Nathan Sharon (1925–2011) (2011) (0)
Chapter 5 Biosynthesis 1. Introduction (1995) (0)
Reports of meetings (1994) (0)
Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans : UDP-N-acetylglucosamine : a-3-D-mannoside ( 8-1 , 2N-acetylglucosaminyltransferase I ( glycoprotein / glycosylation / glycosyltransferase / polymerase chain reactio (0)
Obituary: Annette Herscovics (1938–2008) (2009) (0)
Letter to the Glyco-Forum The 11th International Symposium on Glycoconjugates (1991) (0)
Abstracts 30th Meeting of the European Metabolic Group (2005) (0)
Presence of Cytidine S'-Monophospho-TV-acetylneuraminic Acid:Gal/21- 3GalNAc-R a(2-3)-Sialyltransferase in Normal Human Leukocytes and Increased Activity of This Enzyme in Granulocytes from Chronic Myelogenous Leukemia Patients1 (2006) (0)
Glycobiology Group Colloquium on Advances in Structural Glycobiology, in honour of Professor Akira Kobata, held during the 649th meeting of the British Biochemical Society, Imperial College, London, December 20 1993. (1994) (0)
INTRACELLULAR LOCALIZATION OF GLYCOSYLTRANSFERASES IN A GOLGI-RICH FRACTION FROM RAT LIVER (1970) (0)
Obituary: Nathan Sharon, 1925–2011 (2011) (0)
G.P.2.06 Walker–Warburg syndrome with POMT1 mutations can be associated with cleft lip and cleft palate (2008) (0)
Identification of a GDP-Fuc:Gal beta 1-3GalNAc-R (Fuc to Gal) alpha 1-2 fucosyltransferase and a GDP-Fuc:Gal beta 1-4GlcNAc (Fuc to GlcNAc) alpha 1-3 fucosyltransferase in connective tissue of the snail Lymnaea stagnalis. (1996) (0)
NICHTVERWENDUNG DES SICHERHEITSGURTES ODER STURZHELMES UNTER STRAFSANKTION - SIND ZIVILRECHTLICHE SANKTIONEN AUCH WEITERHIN ERFORDERLICH? (1982) (0)
S2.2 Molecular cloning and localization to chromosome 14 of the human UDP-N-acetylglucosamine:α-6-D-mannosideβ-1,2-N-acetylglucosaminyltransferase II gene (MGAT2) (1993) (0)
S2.7 Molecular cloning and expression of cDNA encoding rat UDP-N-acetylglucosamine:α-6-d-mannosideβ-1,2-N-acetylglucosaminyltransferase II (1993) (0)
9th annual symposium on biotechnology: the new biology of carbohydrates. University College London Medical School, 16-17 December 1993. (1994) (0)
Studies of 11beta-hydroxylation by beef adrenal mitochondria. (1976) (0)
Letter to the Glyco-Forum: Walter Thomas James Morgan: 1900–2003 (2003) (0)
Branching of N‐Glycans: N‐Acetylglucosaminyltransferases (2008) (0)
The Biosynthesis of Bovine Submaxillary Mucin (1966) (0)
Decreased UDP-GlcNAc:Glycopeptideβ-2-N-Acetylglucosaminyltransferase II activity in a ricin-resistant mutant of baby hamster kidney (BHK) cells (1984) (0)
GRUNDSAETZE DER OESTERREICHISCHEN STRASSENVERKEHRSORDNUNG (1975) (0)
Table of Contents (1994) (0)
Robert Spiro Obituary (2015) (0)
Complex N-glycans: the story of the “yellow brick road” (2013) (0)
Building Units of Oligosaccharides. Part 110. Synthesis of Potential Inhibitors of N-Acetylglucosaminyltransferase I. (1995) (0)
GDP-fucose: beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1 leads to 6GlcNAc)-Asn-peptide) alpha 1 leads to 3-fucosyltransferase activity in honeybee (Apis mellifica) venom glands (1991) (0)
FIGURE 8.1, [Types of N-glycans. N-glycans added...]. (2009) (0)
Qualitative Differences intheN-Acetyl-D-galactosaminyltransferases Produced byHumanAlandA2Genes (1973) (0)
Abstract 1484: Inhibition of the glycosylation enzyme Mgat1 blocks migration, invasion and metastasis of malignant cells (2011) (0)
Synthesis and intracellular transport of glycoproteins. (1976) (0)
3.03 – Glycosyltransferases Involved in N-Glycan Synthesis (1999) (0)
Preface to the Special Issue, “Lower Organisms: Essential to Comparative Glycomics” (2001) (0)

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