Christine Winterbourn | Academic Influence

Christine Winterbourn's AcademicInfluence.com Rankings

Christine Winterbourn

Biology

#3086

World Rank

#4772

Historical Rank

Pathology

#28

World Rank

#66

Historical Rank

biology Degrees

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Biology

Christine Winterbourn's Degrees

Masters Medicine University of New Zealand
PhD Biochemistry University of New Zealand

Why Is Christine Winterbourn Influential?

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According to Wikipedia, Christine Coe Winterbourn is a New Zealand biochemist. She is a professor of pathology at the University of Otago, Christchurch. Her research in the biological chemistry of free radicals earned her the 2011 Rutherford Medal and the Marsden Medal, the top awards from each of New Zealand's two top science bodies.

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Christine Winterbourn's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Reconciling the chemistry and biology of reactive oxygen species. (2008) (1899)
Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. (1998) (1611)
Thiol chemistry and specificity in redox signaling. (2008) (1106)
The estimation of red cell superoxide dismutase activity. (1975) (1058)
Toxicity of iron and hydrogen peroxide: the Fenton reaction. (1995) (989)
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide. (1999) (697)
Protein carbonyl measurement by a sensitive ELISA method. (1997) (684)
Unraveling the biological roles of reactive oxygen species. (2011) (653)
Myeloperoxidase: a key regulator of neutrophil oxidant production. (1997) (609)
Modeling the Reactions of Superoxide and Myeloperoxidase in the Neutrophil Phagosome (2006) (518)
Myeloperoxidase: a front‐line defender against phagocytosed microorganisms (2013) (491)
Reactive Oxygen Species and Neutrophil Function. (2016) (476)
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling. (2010) (429)
Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite. (1985) (428)
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). (2000) (426)
Redox reactions and microbial killing in the neutrophil phagosome. (2013) (352)
Thiocyanate and chloride as competing substrates for myeloperoxidase. (1997) (347)
Superoxide as an intracellular radical sink. (1993) (345)
The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells. (2014) (345)
Biomarkers of myeloperoxidase-derived hypochlorous acid. (2000) (343)
Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus (2012) (339)
[26] Oxidative reactions of hemoglobin (1990) (335)
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction. (2007) (335)
The High Reactivity of Peroxiredoxin 2 with H2O2 Is Not Reflected in Its Reaction with Other Oxidants and Thiol Reagents* (2007) (332)
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate. (2001) (308)
The biological chemistry of hydrogen peroxide. (2013) (306)
Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils (*) (1995) (296)
Activated oxygen and haemolysis. (1975) (290)
On the participation of higher oxidation states of iron and copper in Fenton reactions. (1989) (287)
Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide (2012) (266)
The reaction of superoxide with reduced glutathione. (1994) (260)
Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte. (2007) (256)
Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals. (1979) (254)
Living with a Killer: The Effects of Hypochlorous Acid on Mammalian Cells (2000) (248)
Reactions involving superoxide and normal and unstable haemoglobins. (1976) (244)
Assays for the chlorination activity of myeloperoxidase. (1994) (242)
Hydroxyl radical production in body fluids. Roles of metal ions, ascorbate and superoxide. (1981) (231)
Myeloperoxidase (2000) (228)
Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. (1992) (228)
Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid. (2002) (217)
Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide. (1997) (214)
Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils (1996) (207)
Hydrogen peroxide: A central player in physical plasma-induced oxidative stress in human blood cells (2014) (200)
Free-radical production and oxidative reactions of hemoglobin. (1985) (195)
Chlorination of Bacterial and Neutrophil Proteins during Phagocytosis and Killing of Staphylococcus aureus * (2002) (183)
Oxidative reactions of hemoglobin. (1990) (181)
Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfides. (2010) (179)
Peroxiredoxin 2 and peroxide metabolism in the erythrocyte. (2008) (175)
Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. (1991) (166)
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells. (2005) (160)
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology (2022) (157)
Inhibition of myeloperoxidase by benzoic acid hydrazides. (1995) (155)
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid. (1988) (154)
Are free radicals involved in thiol-based redox signaling? (2015) (147)
Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. (1987) (142)
Reduced glutathione in combination with superoxide dismutase as an important biological antioxidant defence mechanism. (1989) (140)
Lethal Weapons (2002) (139)
The Relationship of CSF and Plasma Cytokine Levels to Cerebral White Matter Injury in the Premature Newborn (2005) (137)
Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid. (1997) (135)
Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride. (1985) (135)
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl. (1991) (134)
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling (2014) (132)
Detection of oxidant sensitive thiol proteins by fluorescence labeling and two‐dimensional electrophoresis (2002) (132)
Nitrite as a Substrate and Inhibitor of Myeloperoxidase (2000) (131)
Doxorubicin-dependent lipid peroxidation at low partial pressures of O2. (1985) (130)
Protein carbonyl measurements show evidence of early oxidative stress in critically ill patients (2000) (130)
6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation. (1989) (129)
Protein carbonyl measurement by enzyme-linked immunosorbent assay. (1999) (128)
Elevated Free Radical Products in the Cerebrospinal Fluid of VLBW Infants with Cerebral White Matter Injury (2002) (125)
Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence. (1984) (125)
Chlorination of cholesterol in cell membranes by hypochlorous acid. (1996) (124)
Inhibition of adriamycin‐promoted microsomal lipid peroxidation by β‐carotene, α‐tocopherol and retinol at high and low oxygen partial pressures (1988) (124)
Glutathione-mediated redox cycling of alloxan. Mechanisms of superoxide dismutase inhibition and of metal-catalyzed OH. formation. (1989) (124)
The ability of scavengers to distinguish OH. production in the iron-catalyzed Haber-Weiss reaction: comparison of four assays for OH. (1987) (124)
Superoxide Converts Indigo Carmine to Isatin Sulfonic Acid (2004) (123)
Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid. (1995) (122)
Hyperoxidation of Peroxiredoxins 2 and 3 (2013) (117)
The ‘mitoflash’ probe cpYFP does not respond to superoxide (2014) (115)
Oxidative interactions between haemoglobin and membrane lipid. A liposome model. (1984) (115)
Redox potential and peroxide reactivity of human peroxiredoxin 3. (2009) (114)
The rate of reaction of superoxide radical ion with oxyhaemoglobin and methaemoglobin. (1976) (113)
Studies of hemoglobin denaturation and Heinz body formation in the unstable hemoglobins. (1974) (109)
Radical-radical reactions of superoxide: a potential route to toxicity. (2003) (109)
Reactive oxidants and myeloperoxidase and their involvement in neutrophil extracellular traps (2013) (108)
Myeloperoxidase as an effective inhibitor of hydroxyl radical production. Implications for the oxidative reactions of neutrophils. (1986) (105)
Model for the Exceptional Reactivity of Peroxiredoxins 2 and 3 with Hydrogen Peroxide (2011) (104)
Cytochrome c reduction by semiquinone radicals can be indirectly inhibited by superoxide dismutase. (1981) (104)
Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins. (2009) (103)
Ceruloplasmin Is an Endogenous Inhibitor of Myeloperoxidase* (2013) (101)
Kinetics and mechanisms of the reaction of hypothiocyanous acid with 5-thio-2-nitrobenzoic acid and reduced glutathione. (2009) (100)
The Lipocalin α1-Microglobulin Has Radical Scavenging Activity* (2007) (100)
3-Chlorotyrosine as a Marker of Protein Damage by Myeloperoxidase in Tracheal Aspirates From Preterm Infants: Association With Adverse Respiratory Outcome (2003) (100)
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides. (2004) (100)
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid. (1997) (100)
Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils. (1988) (98)
Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration. (1997) (96)
Biological Production, Detection, and Fate of Hydrogen Peroxide. (2017) (95)
Oxidant‐mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease (2002) (93)
Human neutrophil collagenase cleaves alpha 1-antitrypsin. (1990) (93)
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo (2022) (93)
Elevated Protein Carbonyls and Lipid Peroxidation Products Correlating with Myeloperoxidase in Tracheal Aspirates from Premature Infants (2000) (93)
Thiol Oxidase Activity of Copper,Zinc Superoxide Dismutase* (2002) (92)
Neutrophils adherent to a nonphagocytosable surface (glomerular basement membrane) produce oxidants only at the site of attachment. (1985) (92)
Deoxyribose breakdown by the adriamycin semiquinone and H2O2: evidence for hydroxyl radical participation (1982) (92)
Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase. (2006) (92)
Production of hydroxyl radicals from paraquat radicals and H2O2 (1981) (91)
Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival. (2001) (91)
Membrane changes associated with lysis of red blood cells by hypochlorous acid. (1994) (89)
Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin* (2015) (88)
Characterization of non-covalent oligomers of proteins treated with hypochlorous acid. (2003) (87)
Glutathione Oxidation by Hypochlorous Acid in Endothelial Cells Produces Glutathione Sulfonamide as a Major Product but Not Glutathione Disulfide* (2001) (86)
A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils (1994) (85)
Reactions of superoxide with myeloperoxidase. (2007) (85)
Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase. (1993) (84)
Redox chemistry of biological thiols (2010) (84)
A kinetic analysis of the catalase activity of myeloperoxidase. (2001) (84)
Evidence for the production of hydroxyl radicals from the adriamycin semiquinone and H2O2 (1981) (83)
Mechanism of oxyhaemoglobin breakdown on reaction with acetylphenylhydrazine. (1978) (82)
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. (1999) (81)
Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent. (1983) (80)
Measuring the redox state of cellular peroxiredoxins by immunoblotting. (2010) (79)
Methods for quantifying phagocytosis and bacterial killing by human neutrophils. (1999) (79)
Protein Carbonyls and Lipid Peroxidation Products as Oxidation Markers in Preterm Infant Plasma: Associations with Chronic Lung Disease and Retinopathy and Effects of Selenium Supplementation (2000) (77)
Oxidative denaturation in congenital hemolytic anemias: the unstable hemoglobins. (1990) (77)
Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction. (1986) (77)
Chelated iron-catalyzed OH. formation from paraquat radicals and H2O2: mechanism of formate oxidation. (1984) (75)
Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry. (1993) (74)
Superoxide dismutase as an inhibitor of reactions of semiquinone radicals (1978) (73)
Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates* (2009) (73)
IκB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-κB activity by glycine chloramine through methionine oxidation (2006) (72)
The High Reactivity of Peroxiredoxin 2 with H 2 O 2 Is Not Reflected in Its Reaction with Other Oxidants and (2007) (72)
Interaction with substrate sensitises caspase‐3 to inactivation by hydrogen peroxide (2002) (72)
Generation of superoxide and tyrosine peroxide as a result of tyrosyl radical scavenging by glutathione. (1995) (72)
Redox biology: signaling via a peroxiredoxin sensor. (2015) (72)
Production of glutathione sulfonamide and dehydroglutathione from GSH by myeloperoxidase-derived oxidants and detection using a novel LC-MS/MS method. (2006) (71)
Oxidation of human haemoglobin by copper. Mechanism and suggested role of the thiol group of residue beta-93. (1977) (70)
The Effect of Gestational Age and Labour on Markers of Lipid and Protein Oxidation in Cord Plasma (2004) (70)
Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry. (2009) (70)
Auto-oxidation of dialuric acid, divicine and isouramil. Superoxide dependent and independent mechanisms. (1989) (70)
Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins. (1997) (69)
Superoxide-dependent hydroxylation by myeloperoxidase. (1994) (66)
Myeloperoxidase-dependent generation of a tyrosine peroxide by neutrophils. (1997) (65)
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity. (2004) (64)
Oxidation contributes to low glutathione in the airways of children with cystic fibrosis (2014) (63)
Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing. (1995) (63)
Elevated Protein Carbonyls as Plasma Markers of Oxidative Stress in Acute Pancreatitis (2003) (62)
Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode. (1989) (62)
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins. (2000) (61)
The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin. (1988) (61)
Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase. (1992) (60)
Degradation of glomerular basement membrane by human neutrophils in vitro. (1984) (60)
Myeloperoxidase-dependent oxidative inactivation of neutrophil neutral proteinases and microbicidal enzymes. (1987) (60)
The mechanism of myeloperoxidase-dependent chlorination of monochlorodimedon. (1988) (58)
Release of iron from ferritin by semiquinone, anthracycline, bipyridyl, and nitroaromatic radicals. (1989) (58)
Angiotensin Type-1 Receptor A1166C Gene Polymorphism Correlates With Oxidative Stress Levels in Human Heart Failure (2006) (57)
A GENETICALLY ENGINEERED MUTANT OF α1-ANTITRYPSIN PROTECTS CONNECTIVE TISSUE FROM NEUTROPHIL DAMAGE AND MAY BE USEFUL IN LUNG DISEASE (1984) (57)
Inhibition by nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine. (1987) (57)
Assay of superoxide dismutase activity in a plate assay using WST-1. (2017) (56)
Low-density lipoprotein accumulation in actively growing xanthomas. (1967) (56)
Superoxide enhances hypochlorous acid production by stimulated human neutrophils. (1990) (55)
The reaction of menadione with haemoglobin. Mechanism and effect of superoxide dismutase. (1979) (54)
Lipid composition of human red cells of different ages. (1970) (54)
Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine. (1987) (53)
Oxidation of hydroquinone by myeloperoxidase. Mechanism of stimulation by benzoquinone. (1992) (53)
Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and citrate, ATP, ADP, and pyrophosphate iron chelates. (1987) (53)
Bacterial killing by neutrophils in hypertonic environments. (1994) (53)
Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry. (2013) (52)
Radical driven Fenton reactions--evidence from paraquat radical studies for production of tetravalent iron in the presence and absence of ethylenediaminetetraacetic acid. (1987) (52)
Protection by Ascorbate against Acetylphenylhydrazine‐Induced Heinz Body Formation in Glucose‐6‐Phosphate Dehydrogenase Deficient Erythrocytes (1979) (52)
The effect of oxidants on neutrophil-mediated degradation of glomerular basement membrane collagen. (1986) (51)
Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46. (2013) (50)
Differential reactivities of hypochlorous and hypobromous acids with purified Escherichia coli phospholipid: formation of haloamines and halohydrins. (1998) (50)
Revisiting the reactions of superoxide with glutathione and other thiols. (2016) (49)
Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione. (2003) (49)
Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion (2009) (49)
Extracellular Oxidation by Taurine Chloramine Activates ERK via the Epidermal Growth Factor Receptor* (2004) (49)
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. (2010) (49)
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic. (2012) (49)
Activation of human neutrophil gelatinase by endogenous serine proteinases. (1988) (48)
İron binding to microsomes and liposomes in relation to lipid peroxidation (1987) (48)
Concerted antioxidant activity of glutathione and superoxide dismutase (1995) (47)
2 Neutrophil Oxidants: Production and Reactions (1990) (46)
Selenium and Glutathione Peroxidase Levels in Premature Infants in a Low Selenium Community (Christchurch, New Zealand) (1992) (46)
A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide. (1988) (45)
Superoxide-mediated Formation of Tyrosine Hydroperoxides and Methionine Sulfoxide in Peptides through Radical Addition and Intramolecular Oxygen Transfer* (2009) (45)
Ferritin, lipid peroxidation and redox-cycling xenobiotics. (1991) (45)
Factors that influence the deoxyribose oxidation assay for Fenton reaction products. (1991) (45)
[7] Reaction of superoxide with glutathioneand other thiols (1995) (44)
Chlorine transfer between glycine, taurine, and histamine: reaction rates and impact on cellular reactivity. (2004) (43)
Oxidation of methionine to dehydromethionine by reactive halogen species generated by neutrophils. (2009) (43)
Protein carbonyl measurement by ELISA. (2002) (43)
Neutrophil extracellular trap formation is elicited in response to cold physical plasma (2016) (43)
Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione. (2009) (43)
Reactions of Adriamycin with haemoglobin. Superoxide dismutase indirectly inhibits reactions of the Adriamycin semiquinone. (1982) (42)
Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells. (2008) (42)
Peroxidase-mediated bromination of unsaturated fatty acids to form bromohydrins. (1996) (41)
Oxidation of 2-cys peroxiredoxins in human endothelial cells by hydrogen peroxide, hypochlorous acid, and chloramines. (2012) (41)
Interaction of adenanthin with glutathione and thiol enzymes: selectivity for thioredoxin reductase and inhibition of peroxiredoxin recycling. (2014) (41)
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation. (2006) (40)
Ferritin-dependent lipid peroxidation by stimulated neutrophils: inhibition by myeloperoxidase-derived hypochlorous acid but not by endogenous lactoferrin. (1990) (40)
Kinetic Approaches to Measuring Peroxiredoxin Reactivity (2016) (40)
Increased thrombin-induced polymerization of fibrinogen associated with high protein carbonyl levels in plasma from patients post myocardial infarction. (2010) (40)
Separation of brain gangliosides by column chromatography on DEAEcelldose (1971) (40)
Neutrophil‐mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation (2013) (39)
Contributions of superoxide, hydrogen peroxide, and transition metal ions to auto-oxidation of the favism-inducing pyrimidine aglycone, divicine, and its reactions with haemoglobin. (1986) (39)
Protein chlorination in neutrophil phagosomes and correlation with bacterial killing. (2014) (38)
Reactions of superoxide with myeloperoxidase and its products. (2004) (38)
Changes in ascorbate levels on stimulation of human neutrophils. (1983) (38)
Superoxide-dependent production of hydroxyl radicals in the presence of iron salts (1982) (36)
Microsomal reduction of low-molecular-weight Fe3+ chelates and ferritin: enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen. (1988) (36)
Nuclear Factor κB Activation in Pulmonary Leukocytes from Infants with Hyaline Membrane Disease: Associations with Chorioamnionitis and Ureaplasma urealyticum Colonization (2005) (36)
The Attachment of Heinz Bodies to the Red Cell Membrane (1973) (35)
Oxidative stress and high-density lipoprotein function in Type I diabetes and end-stage renal disease. (2005) (34)
Inhibition of copper-catalyzed cysteine oxidation by nanomolar concentrations of iron salts. (2004) (34)
Cross-linking methionine and amine residues with reactive halogen species. (2014) (34)
Biological chemistry of superoxide radicals (2020) (33)
Gelatinase contributes to the degradation of glomerular basement membrane collagen by human neutrophils. (1988) (33)
Heterogeneity of hypochlorous acid production in individual neutrophil phagosomes revealed by a rhodamine-based probe (2018) (32)
Adriamycin-dependent peroxidation of rat liver and heart microsomes catalysed by iron chelates and ferritin. Maximum peroxidation at low oxygen partial pressures. (1988) (32)
Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils. (1994) (32)
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades (2019) (32)
Free radical inactivation of rabbit muscle creatinine kinase: catalysis by physiological and hydrolyzed ICRF-187 (ICRF-198) iron chelates. (1994) (31)
dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxymethyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine-1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin. (1990) (31)
Chloramines and hypochlorous acid oxidize erythrocyte peroxiredoxin 2. (2009) (31)
Fatty acid chlorohydrins and bromohydrins are cytotoxic to human endothelial cells (2001) (31)
High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction (2014) (31)
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction. (1993) (31)
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure (2017) (31)
Do neutrophils produce ozone? An appraisal of current evidence (2005) (31)
Biomarkers of Neutrophil-Mediated Glutathione and Protein Oxidation in Tracheal Aspirates From Preterm Infants: Association With Bacterial Infection (2011) (30)
Reactions of superoxide with the myoglobin tyrosyl radical. (2010) (30)
Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention (2015) (30)
Red Cell Superoxide Dismutase Activity in the Newborn (1977) (30)
Haemoglobin denaturation, lipid peroxidation and haemolysis in phenylhydrazine-induced anaemia. (1984) (29)
Release of iron from ferritin by divicine, isouramil, acid-hydrolyzed vicine, and dialuric acid and initiation of lipid peroxidation. (1989) (28)
Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition. (2014) (28)
Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical. (1991) (28)
The lipocalin alpha1-microglobulin has radical scavenging activity. (2007) (28)
Factors influencing local and systemic levels of plasma myeloperoxidase in ST-segment elevation acute myocardial infarction. (2010) (28)
Superoxide dismutase (glu100 → gly) in a family with inherited motor neuron disease: detection of mutant superoxide dismutase activity and the presence of heterodimers (1995) (26)
Inhibition of autoxidation of divicine and isouramil by the combination of superoxide dismutase and reduced glutathione. (1989) (26)
Characterization of Heinz Bodies in Unstable Haemoglobin Haemolytic Anaemia (1972) (26)
Kinetic analysis of structural influences on the susceptibility of peroxiredoxins 2 and 3 to hyperoxidation. (2016) (25)
Analysis of neutrophil bactericidal activity. (2007) (25)
Haemoglobin--a frustrated oxidase? Implications for red cell metabolism. (1977) (25)
Molecular structure and dynamic properties of a sulfonamide derivative of glutathione that is produced under conditions of oxidative stress by hypochlorous acid. (2008) (25)
Thiol oxidation and inhibition of Ca-ATPase by adriamycin in rabbit heart microsomes. (1990) (24)
Release of iron from phagocytosed Escherichia coli and uptake by neutrophil lactoferrin. (1990) (24)
Hyperoxidation of peroxiredoxins 2 and 3: Rate constants for the reactions of the sulfenic acid of the peroxidatic cysteine (2013) (24)
Activation of NF‐κB in human neutrophils during phagocytosis of bacteria independently of oxidant generation (1998) (24)
Myeloperoxidase-dependent Lipid Peroxidation Promotes the Oxidative Modification of Cytosolic Proteins in Phagocytic Neutrophils* (2015) (24)
Endotracheal suctioning of the neonate: Comparison of two methods as a source of mucus material for research (1997) (23)
Extracellular amino acids and lipid peroxidation products in periventricular white matter during and after cerebral ischemia in preterm fetal sheep (2008) (23)
Reaction of superoxide with glutathione and other thiols. (1995) (22)
Superoxide dismutase-inhibitible reduction of cytochrome c by the alloxan radical. Implications for alloxan cytotoxicity. (1982) (22)
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. (1999) (21)
Dietary selenium. (1992) (21)
Hydrogen peroxide reactivity and specificity in thiol-based cell signalling. (2020) (21)
Neutrophil-mediated oxidation of enkephalins via myeloperoxidase-dependent addition of superoxide. (2010) (21)
Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists, 1994: FREE RADICAL TOXICOLOGY AND ANTIOXIDANT DEFENCE (1995) (21)
Mechanism of nitrite oxidation by eosinophil peroxidase: implications for oxidant production and nitration by eosinophils. (2006) (21)
Susceptibilities of lactoferrin and transferrin to myeloperoxidase-dependent loss of iron-binding capacity. (1988) (21)
Interactions between peroxiredoxin 2, hemichrome and the erythrocyte membrane (2016) (21)
Measurement of reaction products from hypochlorous acid and unsaturated lipids. (1994) (21)
Markers of oxidative injury in the cerebrospinal fluid of a premature infant with meningitis and periventricular leukomalacia. (2002) (20)
Oxidative metabolism of amsacrine by the neutrophil enzyme myeloperoxidase. (1992) (20)
The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction (2009) (20)
Roles of superoxide and myeloperoxidase in ascorbate oxidation in stimulated neutrophils and H2O2-treated HL60 cells. (2011) (20)
Assessment of redox changes to hydrogen peroxide-sensitive proteins during EGF signaling. (2011) (20)
Analysis of neutrophil bactericidal activity. (2014) (20)
Problems Associated with Collecting Breath Condensate for the Measurement of Exhaled Hydrogen Peroxide from Neonates on Respiratory Support (2003) (19)
Tetravalent vanadium releases ferritin iron which stimulates vanadium-dependent lipid peroxidation. (1991) (19)
Spectral and kinetic evidence for reaction of superoxide with compound I of myeloperoxidase. (2011) (19)
Inhibition of adriamycin-promoted microsomal lipid peroxidation by beta-carotene, alpha-tocopherol and retinol at high and low oxygen partial pressures. (1988) (19)
Concerted action of reduced glutathione and superoxide dismutase in preventing redox cycling of dihydroxypyrimidines, and their role in antioxidant defence. (1990) (19)
Enhanced hyperoxidation of peroxiredoxin 2 and peroxiredoxin 3 in the presence of bicarbonate/CO2. (2019) (18)
The effect of hypochlorous acid on the expression of adhesion molecules and activation of NF-kappaB in cultured human endothelial cells. (2002) (18)
Proteomic detection of oxidized and reduced thiol proteins in cultured cells. (2009) (18)
Peroxiredoxin interaction with the cytoskeletal‐regulatory protein CRMP2: Investigation of a putative redox relay (2018) (18)
Protein thiol oxidation and formation of S-glutathionylated cyclophilin A in cells exposed to chloramines and hypochlorous acid. (2012) (18)
The Absence of Lipid Peroxidation in Human Red Cells Exposed to Acetylphenylhydrazine (1972) (18)
Neutrophil granule proteins generate bactericidal ammonia chloramine on reaction with hydrogen peroxide (2017) (16)
Unstable Haemoglobin Haemolytic Crises: Contributions of Pyrexia and Neutrophil Oxidants (1981) (16)
Increased basal oxidation of peroxiredoxin 2 and limited peroxiredoxin recycling in glucose‐6‐phosphate dehydrogenase‐deficient erythrocytes from newborn infants (2014) (16)
Nuclear magnetic resonance characterization of 6α-chloro-5β-cholestane-3β,5-diol formed from the reaction of hypochlorous acid with cholesterol (1997) (16)
Hemoglobin oxidation and inter-relationship with lipid peroxidation in the red cell. (1985) (16)
Small bowel ischaemia-reperfusion increases plasma concentrations of oxidised proteins in rats. (1999) (15)
Hexose monophosphate shunt-stimulated reduction of methemoglobin by divicine. (1985) (15)
Evaluating the bactericidal action of hypochlorous acid in culture media. (2020) (14)
The uptake of plasma fatty acids into human red cells and its relationship to cell age. (1970) (14)
Human neutrophil collagenase cleaves x 1-antitrypsin (2005) (14)
Biological Chemistry of Reactive Oxygen Species (2012) (14)
Interactions of staphyloxanthin and enterobactin with myeloperoxidase and reactive chlorine species. (2018) (14)
Characterisation of peroxidasin activity in isolated extracellular matrix and direct detection of hypobromous acid formation. (2018) (14)
Cleavage of alpha 1-antitrypsin by human neutrophil collagenase. (1992) (13)
Conjugation of Glutathione to Oxidized Tyrosine Residues in Peptides and Proteins* (2012) (13)
Superoxide dismutase protects ribonucleotide reductase from inactivation in yeast. (2018) (13)
The influence of superoxide on the production of hypochlorous acid by human neutrophils. (1991) (12)
Decreased thermal stability of red blood cellglu100→gly superoxide dismutase from a family with amyotrophic lateral sclerosis (1995) (12)
Nutritional antioxidants: their role in disease prevention. (1995) (12)
Microsomal lipid peroxidation induced by Adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study (2004) (12)
Detection of apoptosis by caspase‐3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF‐κB activation (2005) (12)
BRAIN LIPIDS OF MICE HOMOZYGOUS FOR THE GENE‘DILUTE LETHAL’(d1) (1971) (12)
Incorporation of [I-14C]palmitate into the lipids of bovine blood cells. (1968) (12)
Increase in selenium status of Christchurch adults associated with deregulation of the wheat market. (1992) (11)
Haemoglobin oxidation and free radical production in the red cell. (1983) (11)
The unstable hemoglobins. (1980) (10)
Myeloperoxidase-dependent loss of malondialdehyde: a limitation for detecting neutrophil-mediated lipid peroxidation. (1993) (10)
Conjugation of glutathione to oxidized tyrosine residues in peptides and proteins. (2015) (10)
Peroxidasin mediates bromination of tyrosine residues in the extracellular matrix (2020) (10)
Free radical toxicology and antioxidant defence. (1995) (9)
Radical Scavenging by Thiols and the Fate of Thiyl Radicals (2013) (9)
Regulation of intracellular glutathione☆ (2018) (9)
Free Radical Biology of Iron (1991) (9)
Chapter 12:Myeloperoxidase: Structure and Function of the Green Heme Peroxidase of Neutrophils (2015) (9)
Inhibition of DNA methylation in proliferating human lymphoma cells by immune cell oxidants (2020) (8)
Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation. (1987) (8)
Induction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils. (2020) (8)
An iron chelator is not required for reductive iron release from ferritin by radical generating systems. (1989) (8)
Erratum to “Chlorine transfer between glycine, taurine, and histamine: Reaction rates and impact on cellular reactivity” [Free Radic. Biol. Med. 36 (2004) 1622–1630] (2005) (8)
Low density lipoprotein peptide metabolism in nephrotic syndrome: a comparison with patterns observed in other syndromes characterised by hyperlipoproteinaemia. (1970) (8)
Syndrome of the seablue histiocyte. (1974) (7)
Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2. (2020) (7)
Free-Radical Production from Acetylphenylhydrazine and Haemoglobin (1977) (7)
Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2 (2021) (7)
Current methods to study reactive oxygen species--pros and cons. Preface. (2014) (6)
Haemoglobin north shore, β134 ValåGlu, a new unstable haemoglobin (1977) (6)
EFFECT OF ORAL AIIMINISTRATION OF ASCOKBATE ON ACETYLPHENYLHYDRAZINE‐INDUCED HEINZ BODY FORMATION (1980) (6)
Peroxidasin protein expression and enzymatic activity in metastatic melanoma cell lines are associated with invasive potential (2021) (6)
Hydrogen peroxide signaling via its transformation to a stereospecific alkyl hydroperoxide that escapes reductive inactivation (2021) (6)
Role of the Gut in Synthesizing the Protein Component of Low-density (Beta) Lipoprotein (1965) (6)
A curious case of cysteines in human peroxiredoxin I (2020) (6)
Oxidative hemoglobin breakdown induced by a rubber additive. (1981) (6)
Deciphering the in vivo redox behavior of human peroxiredoxins I and II by expressing in budding yeast. (2019) (5)
Rapid proteolysis of unstable globins in human bone marrow (1983) (5)
High-affinity iron binding by xanthine oxidase. (1986) (5)
Low selenium and infant health in Christchurch. (1990) (5)
Use of a Proteomic Technique to Identify Oxidant‐Sensitive Thiol Proteins in Cultured Cells (2006) (5)
A monoclonal antibody recognizing the chlorohydrin derivatives of oleic acid for probing hypochlorous acid involvement in tissue injury. (1997) (5)
Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2 (2020) (5)
Peroxiredoxin expression and redox status in neutrophils and HL‐60 cells (2019) (5)
Reactions of myeloperoxidase with superoxide and hydrogen peroxide: significance for its function in the neutrophil. (1988) (5)
OXIDATION OF HUMAN HEMOGLOBIN BY COPPER: SPECIFICITY FOR BETA CHAINS AND FORMATION OF MODIFIED PRECURSOR (1978) (5)
Redox regulation of neutrophil function. (2002) (5)
Corrigendum to "Assay of superoxide dismutase activity in a plate assay using WST-1" [Free Radic. Biol. Med. 103 (2017) 188-191]. (2017) (4)
The Enigma of 2-Cys Peroxiredoxins: What Are Their Roles? (2021) (4)
Superoxide dismutase-inhibitible reduction ofcytochrom:e cbythealloxan radical (1982) (4)
ROLE OF METAL CHELATING AGENTS AS CATALYSTS IN AN ·OH FORMING PROCESS - A COMPARISON WITH THE HABER-WEISS REACTION (1984) (4)
The reaction of hemoglobin with paraquat radicals in the presence and absence of O2. (1983) (4)
Correction to Redox Potential and Peroxide Reactivity of Human Peroxiredoxin 3 (2010) (4)
Reactions of Myeloperoxidase and Production of Hypochlorous Acid in Neutrophil Phagosomes (2000) (3)
Nuclear magnetic resonance characterization of 6 alpha-chloro-5 beta-cholestane-3 beta,5-diol formed from the reaction of hypochlorous acid with cholesterol. (1997) (3)
Hemoglobin autoxidation: the risk of the red cell and the contribution of copper. (1978) (3)
Isolation of high oxygen affinity hemoglobins. (1977) (3)
CHAPTER 8. Reactive Oxygen Species in Biological Systems (2019) (3)
Metabolism in vivo of bovine erythrocyte lipids. (1968) (2)
Neutrophil NET Formation with Microbial Stimuli Requires Late Stage NADPH Oxidase Activity (2021) (2)
The common G-866 A polymorphism of the UCP 2 gene and survival in diabetic patients following myocardial infarction (2015) (2)
Corrigendum to “Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition” [Free Radic. Biol. Med. 70 (2014) 86–95] (2015) (2)
Proteinase-antiproteinase bbalance in ttracheal aaspirates ffrom nneonates (1994) (2)
Superoxide: The enigmatic chemical chameleon in neutrophil biology (2023) (2)
Randomised Controlled Trial of Selenium Supplementation in New Zealand VLBW Infants ♦ 1508 (1998) (2)
Radical Scavenging by Thiols: Biological Significance and Implications for Redox Signaling and Antioxidant Defense (2003) (2)
Oxidative inactivation of neutrophil granule proteinases: implications for neutrophil-mediated proteolysis. (1988) (2)
Reactivity of the p-93 Sh Groups in Hb Köln (1976) (2)
Hyperoxidation of Peroxiredoxins 2 and 3 RATECONSTANTSFORTHEREACTIONSOFTHESULFENICACIDOFTHEPEROXIDATIC (2013) (2)
Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin (2018) (1)
Heparin, But Not Bilvalirudin, Liberates Endothelial Myeloperoxidase in Patients with ST Elevation Myocardial Infarction (STEMI) (2007) (1)
Haemoglobin North Shore, beta134 Val replaced by Glu, a new unstable haemoglobin. (1977) (1)
Oxidation of unsaturated membrane phospholipids and cholesterol by hypochlorous acid (1993) (1)
Superoxide-mediated post-translational modification of tyrosine residues (2015) (1)
Favism and Glucose-6-Phosphate Dehydrogenase Deficiency. (2018) (1)
Reaffirming professionalism in medicine. (2001) (1)
Induction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils. (2021) (0)
The Red Cell: Fifth Ann Arbor Conference Progress in Clinical and Biological Research: Volume 55 : Edited by G.J. Brewer Alan R. Liss; New York, 1981 xxxiii + 803 pages. £53.20 (1984) (0)
Lipid metabolism of mammalian erythrocytes with special reference to cellular aging : a thesis presented in partial fulfillment of the requirements for the degree of PhD in Biochemistry at Massey University (1968) (0)
Digital Figures (2020) (0)
REACTION OF PARAQUAT RADICALS WITH H2O2 : EFFECT OF O2 AND COMPARISON OF RADICALS GENERATED ENZYMATICALLY AND BY IRRADIATION (1984) (0)
Iron-dependent oxidative inactivation of Ca2+ -ATPase by adriamycin (1990) (0)
Local leukocyte elastase release at site of occlusive plaque rupture predicts downstream microvascular reperfusion injury and impaired left ventricular function in ST elevation myocardial infarction (2008) (0)
The fate of the unstable hemoglobins (1983) (0)
Complex roles of reactive oxygen species in the formation and anti-microbial action of neutrophil NETs (2012) (0)
Oxidation Of Glutathione In The Airways Of Young Children With Cystic Fibrosis (2011) (0)
Increased Basal Oxidation and Limited Recycling of Peroxiredoxin 2 in Glucose-6-Phosphate Dehydrogenase Deficient Erythrocytes (2014) (0)
Interaction of Peroxiredoxin 2 with Collapsin Response Mediator Protein 2 (2016) (0)
hydrogen peroxide in the erythrocyte Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level (2013) (0)
398 – Bacterial Killing and Oxidant Production by Neutrophils from Patients with Cystic Fibrosis (2014) (0)
OXIDATIVE STRESS AND HDL FUNCTION IN END STAGE RENAL DISEASE (2002) (0)
Plasma Myeloperoxidase Levels are Highest in the Infarct-Related Artery (IRA) in Patients with ST Elevation MI (2007) (0)
PSS114 - Hyperoxidised Peroxiredoxin 2 Interacts with the Protein Disulphide Isomerase ERp46 (2013) (0)
84 - Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2 (2016) (0)
The Enigma of 2-Cys Peroxiredoxins: What Are Their Roles? (2021) (0)
The resistance of transferrin, lactoferrin and caeruloplasmin to oxidative damage: a reply (1988) (0)
Hydrogen peroxide dependent interaction of peroxiredoxin 2 with ERp46 (2012) (0)
PSS103 - Detection of Glutathione Conjugated to Oxidised Tyrosine Residues on Proteins (2013) (0)
Kinetics of hyperoxidation of human peroxiredoxin 2 (2012) (0)
239 - Inhibition of Peroxidasin-Mediated Collagen IV Crosslinking (2015) (0)
Acute Myocardial Infarction Plasma Concentrations of Myeloperoxidase Predict Mortality After Myocardial Infarction (2016) (0)
Free-radical production from acetylphenylhydrazine and haemoglobin [proceedings]. (1977) (0)
Plasma Myeloperoxidase at the Culprit Coronary Lesion in Acute Myocardial Infarction (2009) (0)
PSS113 – Neutrophil-Mediated Oxidation of Erythrocyte Peroxiredoxin 2 as a Potential Marker of Oxidative Stress in Inflammation (2013) (0)
Contents Vol. 84, 2003 (2003) (0)
Cross-linking between cysteine and lysine, tryptophan or tyrosine in peptides and proteins treated with hypochlorous acid and other reactive halogens (2023) (0)
i/Z-A^A^'-Dicarboxamidomethyl-^A^'-dicarboxymethyl-l^-diaminopropane (ICRF- 198) and </-l,2-Bis(3,5-dioxopiperazine-l-yl)propane (ICRF-187) Inhibition of Fe3+Reduction, Lipid Peroxidation, and CaATPase Inactivation in Heart Microsomes Exposed to Adriamycin1 (2006) (0)
Inhibition ofmyeloperoxidase bybenzoic acid hydrazides (1995) (0)
Thiol oxidation by chloramines and HOCl (2003) (0)
Plasma Levels of Myeloperoxidase (MPO) and Thiocyanate (SCN-) Predict Mortality in Patients Following Acute Myocardial Infarction (2011) (0)
Tyrosine Residues in Peptides and Proteins Conjugation of Glutathione to Oxidized Protein Structure and Folding (2012) (0)
Redox Proteomics of EGF Signaling (2010) (0)
Plasma antioxidants and protection against alpha-1-proteinase inhibitor inactivation. (1987) (0)
59 NF-Kappa B Activation and Apoptosis in Lung Neutrophils from Infants with Hyaline Membrane Disease (2004) (0)
Peroxidasin-Catalysed Oxidative Modifications of Proteins in the Extracellular Matrix (2016) (0)
Mechanism of Activation of NFKB by Hydrogen Peroxide (1997) (0)
231 - Glutathionylation at the Active Sites of Peroxiredoxin 2 and Recycling by Glutaredoxin (2015) (0)
Original Contribution Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase (2006) (0)
Carbon dioxide/bicarbonate is required for sensitive inactivation of mammalian glyceraldehyde-3-phosphate dehydrogenase by hydrogen peroxide. (2023) (0)
A cautionary note on using phosphatase inhibitors with hydrogen peroxide. (2022) (0)
Reactivity of the beta-93 SH groups in Hb Köln. (1976) (0)
PSS120 – Oxidation of Glutathione by Hypochlorous Acid in theAirways of Children with Cystic Fibrosis (2013) (0)

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