Gregory Stephanopoulos
Greek American chemical engineer
Gregory Stephanopoulos's AcademicInfluence.com Rankings
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Chemistry
Gregory Stephanopoulos's Degrees
- Bachelors Chemical Engineering National Technical University of Athens
Why Is Gregory Stephanopoulos Influential?
(Suggest an Edit or Addition)According to Wikipedia, Greg N. Stephanopoulos is an American chemical engineer and the Willard Henry Dow Professor in the department of chemical engineering at the Massachusetts Institute of Technology. He has worked at MIT, Caltech, and the University of Minnesota in the areas of biotechnology, bioinformatics, and metabolic engineering especially in the areas of bioprocessing for biochemical and biofuel production. Stephanopoulos is the author of over 400 scientific publications with more than 35,000 citations as of April 2018. In addition, Greg has supervised more than 70 graduate students and 50 post-docs whose research has led to more than 50 patents. He was elected a fellow of the American Association for the Advancement of Science , a member of the National Academy of Engineering , and received the ENI Prize on Renewable Energy 2011.
Gregory Stephanopoulos's Published Works
Published Works
- Chemical Process Control: An Introduction to Theory and Practice (1983) (840)
- A review of process synthesis (1981) (359)
- Studies in the synthesis of control structures for chemical processes: Part I: Formulation of the problem. Process decomposition and the classification of the control tasks. Analysis of the optimizing control structures (1980) (272)
- Representation of process trends—Part I. A formal representation framework (1990) (269)
- Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis (2005) (263)
- Wave‐net: a multiresolution, hierarchical neural network with localized learning (1993) (242)
- Intelligent systems in process engineering : A review (1996) (195)
- Formal order-of-magnitude reasoning in process engineering (1989) (159)
- Interactive exploration of microarray gene expression patterns in a reduced dimensional space. (2002) (157)
- Computer‐aided synthesis of biochemical pathways (1990) (149)
- MODEL.LA. A modeling language for process engineering—I. The formal framework (1990) (145)
- Determination of minimum sample size and discriminatory expression patterns in microarray data (2002) (145)
- Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter. (2004) (143)
- Process systems engineering: From Solvay to modern bio- and nanotechnology.: A history of development, successes and prospects for the future (2011) (142)
- Modelling and analysis of traffic queue dynamics at signalized intersections (1979) (141)
- Metabolic flux analysis of hybridoma continuous culture steady state multiplicity. (1999) (132)
- Representation of process trends—III. Multiscale extraction of trends from process data (1994) (127)
- Oversaturated signal systems with queue length constraints—I: Single intersection (1977) (125)
- Representation of process trends—IV. Induction of real-time patterns from operating data for diagnosis and supervisory control (1994) (118)
- Perspectives on the synthesis of plant-wide control structures (2000) (106)
- Studies in the synthesis of control structures for chemical processes: Part II: Structural aspects and the synthesis of alternative feasible control schemes (1980) (105)
- Design-kit: An object-oriented environment for process engineering (1987) (105)
- Rectification of process measurement data in the presence of gross errors (1981) (104)
- Reasoning with Orders of Magnitude and Approximate Relations (1987) (98)
- Studies in the synthesis of control structures for chemical processes: Part III: Optimal selection of secondary measurements within the framework of state estimation in the presence of persistent unknown disturbances (1980) (95)
- Knowledge-Based System Applications in Engineering Design: Research at MIT (1989) (94)
- Bilinear approximation of general non-linear dynamic systems with linear inputs (1980) (92)
- Studies in process synthesis—II: Evolutionary synthesis of optimal process flowsheets☆ (1976) (88)
- Studies in the synthesis of control structures for chemical processes: Part IV. Design of steady‐state optimizing control structures for chemical process units (1980) (85)
- A system‐theoretic, control‐inspired view and approach to process safety (2014) (83)
- Metabolic flux analysis of postburn hepatic hypermetabolism. (2000) (83)
- An application of shock wave theory to traffic signal control (1981) (79)
- Multiobjective dynamic optimization of semibatch copolymerization reactors (1982) (77)
- All Too Human: A Political Education (2000) (77)
- Oversaturated signal systems with queue length constraints—II: Systems of intersections (1977) (76)
- Synthesis of operating procedures for complete chemical plants—I. Hierarchical, structured modelling for nonlinear planning (1988) (73)
- Representation of process trends—Part II. The problem of scale and qualitative scaling (1990) (71)
- On the rectification of measurement errors for complex chemical plants: Steady state analysis (1980) (67)
- MODEL.LA. A modeling language for process engineering—II. Multifaceted modeling of processing systems (1990) (66)
- Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells (2004) (66)
- Effect of reversible reactions on isotope label redistribution--analysis of the pentose phosphate pathway. (1998) (66)
- Studies in process synthesis—I: Branch and bound strategy with list techniques for the synthesis of separation schemes (1975) (63)
- Synthesis of control systems for chemical plants A challenge for creativity (1983) (62)
- OPTIMAL CONTROL OF OVERSATURATED INTERSECTIONS: THEORETICAL AND PRACTICAL CONSIDERATIONS. (1978) (61)
- Mapping physiological states from microarray expression measurements (2002) (61)
- Synthesis of operating procedures for complete chemical plants—II. A nonlinear planning methodology (1988) (58)
- Wavelet‐based modulation in control‐relevant process identification (1998) (56)
- Multiresolution analysis in statistical mechanics. I. Using wavelets to calculate thermodynamic properties (2002) (56)
- Metabolic flux analysis: a powerful tool for monitoring tissue function. (1999) (52)
- Dynamics and control of the Czochralski process: I. Modelling and dynamic characterization (1987) (52)
- Six Degree-of-Freedom Active Vibration Control Using the Stewart Platforms (1994) (52)
- The modular multivariable controller: I: Steady‐state properties (1992) (51)
- On bilinear estimation and control (1981) (49)
- Compression of chemical process data by functional approximation and feature extraction (1996) (49)
- Multiobjective analysis in modeling the petrochemical industry (1980) (49)
- Artificial intelligence in process engineering—current state and future trends (1990) (48)
- Studies in the synthesis of control structures for chemical processes. Part V: Design of steady‐state optimizing control structures for integrated chemical plants (1981) (47)
- Application of Multivariate Analysis to Optimize Function of Cultured Hepatocytes (2003) (46)
- Continuous process improvement through inductive and analogical learning (1992) (44)
- Minimizing unobservability in inferential control schemes (1980) (44)
- Studies on the synthesis of chemical reaction paths—I: Reaction characteristics in the (ΔG, T) space and a primitive synthesis procedure (1982) (44)
- Multiresolution analysis in statistical mechanics. II. The wavelet transform as a basis for Monte Carlo simulations on lattices (2002) (43)
- Mitochondrial membrane potential differentiates cells resistant to apoptosis in hybridoma cultures. (2000) (42)
- Variable measurement structures for the control of a tubular reactor (1981) (42)
- Nanoscale process systems engineering: Toward molecular factories, synthetic cells, and adaptive devices (2005) (41)
- Genomic dissection for characterization of cancerous oral epithelium tissues using transcription profiling. (2003) (39)
- Searching Spaces of Discrete Solutions: The Design of Molecules Possessing Desired Physical Properties (1995) (38)
- Metabolic flux control analysis of branch points: an improved approach to obtain flux control coefficients from large perturbation data. (2004) (38)
- Synthesis of operating procedures for complete chemical plants—III. Planning in the presence of qualitative, mixing constraints (1990) (38)
- Structural operability analysis of heat exchanger networks (1986) (36)
- Dynamics and control of the Czochralski process II. Objectives and control structure design (1988) (35)
- Artificial intelligence in the development and design of biochemical processes (1986) (34)
- Synthesis of biochemical production routes (1992) (34)
- Synthesis of control systems for chemical plants (1996) (32)
- Synthesis of Reaction Mechanisms Consisting of Reversible and Irreversible Steps. 1. A Synthesis Approach in the Context of Simple Examples (1992) (31)
- A structural approach to the design of control systems in heat exchanger networks (1988) (31)
- Inverse modeling using multi-block PLS to determine the environmental conditions that provide optimal cellular function (2004) (30)
- Reasoning in Time: Modeling, Analysis, and Pattern Recognition of Temporal Process Trends (1995) (30)
- The future of expert systems in chemical engineering (1987) (29)
- Variable measurement structures for process control (1981) (29)
- Wave-Nets: novel learning techniques, and the induction of physically interpretable models (1994) (29)
- Plant-Wide Control Structures and Strategies (1998) (27)
- Generation and assessment of batch processes with ecological considerations (1995) (26)
- Agent-based approach to a design support system for the synthesis of continuous chemical processes (1995) (26)
- Wavelets as basis functions for localized learning in a multi-resolution hierarchy (1992) (26)
- Advanced control design considerations for the Czochralski process (1987) (26)
- Synthesis in process development (1986) (25)
- Multi-Scale Aspects in Model-Predictive Control (1998) (25)
- Controlled Formation of Nanostructures with Desired Geometries. 2. Robust Dynamic Paths (2010) (25)
- The 2-port control system (1986) (25)
- Controlled Formation of Nanostructures with Desired Geometries. 1. Robust Static Structures (2010) (25)
- Order-of-magnitude reasoning with O[M] (1989) (24)
- Dynamic sensitivity analysis of chemical reaction systems: A variational method (1982) (23)
- A framework for the language and logic of computer-aided phenomena-based process modeling (2000) (22)
- Valid parameter range analyses for chemical reaction kinetic models (2002) (22)
- Multi-scale modeling, estimation and control of processing systems (1997) (21)
- Knowledge-based validation and waste management of batch pharmaceutical process designs (1996) (21)
- ESTIMATION OF UPPER BOUNDS FOR THE RATES OF ENZYMATIC REACTIONS (1990) (20)
- Studies on the synthesis of chemical reaction paths-II. reaction schemes with two degrees of freedom (1989) (20)
- Thermodynamic bounds and selection of technologies in the petrochemical industry (1980) (19)
- A master-equation approach to simulate kinetic traps during directed self-assembly. (2012) (18)
- Multiscale theory for linear dynamic processes: Part 1. Foundations (2008) (18)
- Developing Process Designs for Biorefineries—Definitions, Categories, and Unit Operations (2020) (17)
- Artificial Intelligence… ‘What Will Its Contributions Be to Process Control’? (1990) (17)
- An estimator for a class of non-linear distributed systems (1982) (16)
- Rapid plant-wide screening of solvents for batch processes (1996) (16)
- Optimizing control of industrial chemical processes: State of the art review (1980) (16)
- Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data (2004) (14)
- OPTIMAL SELECTION OF SECONDARY MEASUREMENTS WITH THE FRAMEWORK OF STATE ESTIMATION IN THE PRESENCE OF PERSISTENT UNKNOWN DISTURBANCES (1980) (14)
- Synthesis of chemical reaction paths : economic and specification constraints (1994) (14)
- Representation and extraction of trends from process data (1992) (13)
- On the behaviour of two stirred tanks in series (1982) (12)
- Large-Scale Concept Detection in Multimedia Data Using Small Training Sets and Cross-Domain Concept Fusion (2010) (12)
- Temporal Representation of Process Trends for Diagnosis and Control (1992) (12)
- A group contribution method for the estimation of equilibrium constants for biochemical reactions (1988) (11)
- Multiscale theory for linear dynamic processes: Part 2. Multiscale model predictive control (MS-MPC) (2008) (11)
- ALGORITHM FOR REAL-TIME CONTROL OF CRITICAL INTERSECTIONS. (1979) (11)
- Automation in Design: The Conceptual Synthesis of Chemical Processing Schemes (1995) (11)
- MODEL. LA A MODELING LANGUAGE FOR PROCESS ENGINEERING. PART I AND II. THE FORMAL FRAMEWORK (1990) (11)
- Controlled Formation of Nanostructures with Desired Geometries (2009) (11)
- A Novel Approach for the Identification of Economic Opportunities within the Framework of a Biorefinery (2015) (10)
- Controlled Formation of Nanostructures with Desired Geometries: Part 3. Dynamic Modeling and Simulation of Directed Self-Assembly of Nanoparticles through Adaptive Finite State Projection (2015) (10)
- Using wavelet transforms for multiresolution materials modeling (2005) (10)
- On-line fault detection and supervision in the chemical process industries 2001 (CHEMFAS-4) : a proceedings volume from the 4th IFAC Workshop, Jejudo Island, Korea, 7-8 June 2001 (2001) (9)
- Batch process development: From reactions to manufacturing systems (1999) (9)
- Design of multi‐actor distributed processing systems: A game‐theoretical approach (2016) (9)
- Topological coarse graining of polymer chains using wavelet-accelerated Monte Carlo. II. Self-avoiding chains. (2005) (9)
- Comments on finding the generic rank of a structural matrix (1978) (9)
- An Intelligent System for Planning Plant-wide Process Control Strategies (1987) (8)
- Topological coarse graining of polymer chains using wavelet-accelerated Monte Carlo. I. Freely jointed chains. (2005) (8)
- Empirical Learning Through Neural Networks: The Wave-Net Solution (1995) (8)
- Synthesis of optimal process flowsheets by an infeasible decomposition technique in the presence of functional non‐convexities (1975) (8)
- Formal modeling of approximate relations in biochemical systems (1989) (8)
- FINITE STABILITY REGIONS FOR LARGE-SCALE SYSTEMS WITH STABLE AND UNSTABLE SUBSYSTEMS. (1977) (8)
- All too Human (2000) (8)
- Inductive and Deductive Reasoning: The Case of Identifying Potential Hazards in Chemical Processes (1995) (7)
- A General Approach to Classify Operational Parameters and Rectify Measurement Errors for Complex Chemical Processes (1980) (7)
- Wave-Net Based On-Line Quality Inference System for Polymerization Processes (1995) (7)
- Hydrothermal Pretreatment: Process Modeling and Economic Assessment Within the Framework of Biorefinery Processes (2017) (7)
- Control studies in an extractive distillation process: simulation and measurement structure (1986) (7)
- Integrating Information, Management and Control in Process Industries (1995) (7)
- SYNTHESIS OF CHEMICAL REACTION PATHS: THE SCOPE OF GROUP CONTRIBUTION METHODS (1994) (7)
- 7.1 — Chemical Process Control Education (1987) (7)
- VITALAS at TRECVID-2009 (2009) (6)
- Stability analysis of structured chemical engineering systems via decomposition (1979) (6)
- Pollution prevention for production systems of energetic materials (1998) (6)
- Multi-Scale Aspects in Linear and Nonlinear Estimation and Control (1998) (5)
- Evaluation of the production of lipids for fuels and proteins from microalgae by decomposition of the processing network (2016) (5)
- Learning at Multiple Resolutions: Wavelets as Basis Functions in Artificial Neural Networks, and Inductive Decision Trees (1994) (5)
- Synthesis of Control Structures for Chemical Plants (1998) (5)
- Real time control of critical intersections based on queue dynamics (1978) (5)
- PROCESS IMPROVEMENT: AN EXPLORATORY DATA ANALYSIS APPROACH WITHIN AN INTERVAL‐BASED OPTIMIZATION FRAMEWORK (2009) (5)
- Process Systems Engineering: From Solvay to the 21st Century. A History of Development, Successes and Prospects for the Future (2009) (5)
- A Research Program on Artificial Intelligence in Process Engineering. (1986) (5)
- A Stronger Version of the Discrete Minimum Principle (1974) (5)
- Two-port control system: a generalized predictive controller (1987) (5)
- On the Application of Explanation-Based Learning to Acquire Control Knowledge for Branch and Bound Algorithms (1998) (5)
- A discussion of the design of steady-state optimizing control structures for chemical processes (1978) (4)
- VITALAS at TRECVID-2008 (2009) (4)
- Linking physiology and transcriptional profiles by quantitative predictive models (2007) (4)
- Exploring Opportunities for the Production of Chemicals from Municipal Solid Wastes within the Framework of a Biorefinery (2015) (4)
- Overcoming deficiencies of the two-level method for systems optimization (1973) (4)
- Controlled Formation of Nanostructures with Desired Geometries. Part 4. Multiresolution Optimal Control in Dynamically Directed Self-Assembly of Nanoparticles (2015) (4)
- WAVELETS AS BASIS FUNCTIONS FOR LOCALIZED LEARNING (1992) (4)
- Modeling Languages: Declarative and Imperative Descriptions of Chemical Reactions and Processing Systems (1995) (4)
- KNOWLEDGE-BASED APPROACHES IN PROCESS SYNTHESIS (1996) (4)
- A decomposition method for the stability analysis of large microbial systems. (1979) (3)
- A Phenomena-Oriented Environment for Teaching Process Modeling: Novel Modeling Software and Its Use in Problem Solving. (1999) (3)
- Optimization of Lignocellulosic Waste Biorefinery using Multi-Actor Multi-Objective Mathematical Framework (2016) (3)
- Control and System Design for the Czochralski Crystal Growth Process (1988) (3)
- A unified approach to the synthesis of control structures for complex chemical plants (1979) (3)
- Thermodynamic availability analysis in the synthesis and analysis of complex processing systems (1979) (3)
- Dynamics and control of process systems 2001 (DYCOPS-6) : a proceedings volume from the 6th IFAC Symposium, Jejudo Island, Korea, 4-6 June 2001 (2001) (2)
- Laying the foundations: An advisor's perspective (2014) (2)
- SYNTHESIS OF HEAT INTEGRATED SEQUENCES. (1982) (2)
- Process design in a dynamic environment: Part I. A decomposition technique to study the stability of chemical engineering systems (1976) (2)
- A Product-Centered Chemical Industry (2001) (2)
- Paradigms from process operations (1995) (2)
- Towards robust fabrication of non-periodic nanoscale systems via directed self assembly (2011) (2)
- Symbolic Computing and Artificial Intelligence in Chemical Engineering: A New Challenge (1991) (2)
- TOWARDS THE SYNTHESIS OF CHEMICAL REACTION PATHS. (1982) (2)
- Wavelet‐accelerated Monte Carlo sampling of polymer chains (2005) (2)
- Multi-Scale Descriptions of Real-Time Trends and their Impact in Pattern Recognition (1991) (2)
- Steady state and dynamic studies of a multi product chemical plant (1975) (2)
- A model for process design automation (1991) (2)
- Design of Optimizing Control Structures for Chemical Plants (1980) (2)
- The Multimedia Understanding Group at TRECVID 2010 (2010) (2)
- A static estimator for use in process control (1977) (2)
- SYNTHESIS IN PROCESS DEVELOPMENT: ISSUES AND SOLUTION METHODOLOGIES. (1985) (2)
- My Fellow Americans: The Most Important Speeches of America's Presidents, from George Washington to George W. Bush (2010) (1)
- An Artificial Intelligence Perspective in the Design of Control Systems for Complete Chemical Processes (1987) (1)
- The Multiscale Nature of Process Dynamics and Model-Predictive Control (2006) (1)
- On-line fault detection and supervision in the chemical process industries : selected papers from the IFAC Symposium, Newark, Delaware, USA, 22-24 April 1992 (1993) (1)
- Modeling and control of biotechnical processes 1992, (2nd IFAC Symposium) and Computer applications in fermentation technology (5th International Conference) : selected papers from the IFAC and ICCAFT 5 meetings, Keystone, Colorado, USA, 29 March - 2 April 1992 (1992) (1)
- Optimum operation and control of chemical plants via constraint control (1979) (1)
- Modeling and dynamic characterization of the czochralski crystal growth process (1993) (1)
- Adaptive Design of Model-Based Controllers (1985) (1)
- Economically optimal multi-actor processing networks: material flows and price assignment of the intermediates using Lagrangian decomposition (2016) (1)
- Optimal Temperature and Catalyst Renewal Policies in a Tubular Reactor with Catalyst Decay (1971) (0)
- Analysis and Optimization of Multi-actor Biorefineries (2019) (0)
- A wavelet transform method for multiresolution materials modeling (2001) (0)
- European Symposium on Computer Aided Process Engineering - 6, ESCAPE-6, 26-29 May 1996, Rhodes, Greece : 29th Symposium of the Working Party on Computer Aided Process Engineering : 541th Event of the European Federation of Chemical Engineers (EFCE) (1996) (0)
- A S YSTEM -T HEORETIC , C ONTROL -I NSPIRED V IEW AND A PPROACH TO P ROCESS S AFETY (2014) (0)
- Coarse-graining of polymer models using wavelet-accelerated Monte Carlo (2004) (0)
- MODEL LEARNING IN MPC : AN INTELLIGENT CONTROL FORMULATION (1996) (0)
- Erratum: Pollution prevention for production systems of energetic materials (Waste Management (1997) 17:2/3 (165-173) PII: S0956053X97100174) (1998) (0)
- Synthesis of chemical reaction paths: a challenge in process development (1985) (0)
- SYNTHESIS OF HEAT RECOVERY NETWORKS FOR CHEMICAL PROCESSES. (1977) (0)
- On the detection and representation of trends (1990) (0)
- BioSep Designer: a process synthesizer for bioseparations (1992) (0)
- Mark Zuckerberg interview with George Stephanopoulos about 2020 election (2019) (0)
- Variable control structures (1980) (0)
- Foundations of Computer-Aided Process Design: Process of the 3rd International Conference, Snowmass Village, CO, July 10-14, 1989 (1990) (0)
- Reduction of a Structured Model to an Equivalent Unstructured Model. (1988) (0)
- A new wavelet-based paradigm for hierarchical coarse-graining applied to materials modeling (2004) (0)
- Fifth International Conference on Intelligent Systems in Process Engineering, Snowmass, Colorado, July 9-14, 1995 (1996) (0)
- OPERABILITY CONSIDERATIONS IN RETROFIT DESIGNS OF HEAT EXCHANGER NETWORKS. (1985) (0)
- Development of Magnetic Field Assisted Melt Stabilization with Heat and Mass Transfer Control in Low Pressure LEC Growth of GaAs (1988) (0)
- AN ALTERNATIVE APPROACH TO THE OPTIMIZATION OF CONSTRAINED DESIGN PROBLEMS (1980) (0)
- Leading undergraduates along structured paths to the building of good process models (1999) (0)
- Success and prospects in process systems (2008) (0)
- Preface to the "Art Westerberg" Festschrift (2004) (0)
- Controlled Formation of Self-assembled Nanostructures with Desired Geometries: Robust Dynamic Paths to Robust Desired Structures (2009) (0)
- Paradigms from product and process design (1995) (0)
- Nonmonotonic Reasoning: The Synthesis of Operating Procedures in Chemical Plants (1995) (0)
- John R. Ragazzini control education award (2009) (0)
- Synthesis of chemical reaction paths (1985) (0)
- A tribute to Neal R. Amundson (2013) (0)
- Principles and Methodologies for the Controlled Formation of Self‐Assembled Nanoscale Structures with Desired Geometries (2011) (0)
- 2.o[m] Formalism Engineering Problem Solving (1999) (0)
- MODAL ANALYSIS AND SECONDARY MEASUREMENT SELECTION FOR THE CONTROLLER DESIGN OF HEAT INTEGRATED DISTILLATION COLUMNS. (1978) (0)
- AGENT-BASED APPROACH FOR THE CONSTRUCTION OF A DESIGN SUPPORT SYSTEM FOR CONCEPTUAL CHEMICAL PROCESS SYNTHESIS (1995) (0)
- Modeling of Biological Systems with Time Delays. (1987) (0)
- AIChE journal: More diverse and timely (1995) (0)
- Reduced Dimensional Space Interactive Exploration of Microarray Gene Expression Patterns in a (2002) (0)
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