Gil Omenn
American professor of internal medicine, human genetics, and public health
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Biology Philosophy
Gil Omenn's Degrees
- Masters Medicine Harvard University
Why Is Gil Omenn Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gilbert S. Omenn is an American medical doctor and researcher. He currently is the Harold T. Shapiro Distinguished University Professor at the University of Michigan; professor of Computational medicine & bioinformatics, Molecular medicine & genetics, Human genetics, and Public health; and the Director of the UM Center for Computational Medicine & Bioinformatics. He is the discover of Omenn syndrome, a genetic disorder that is fatal in infancy unless treated. Omenn has served as editor of the Annual Review of Public Health from 1990–1996. and as president of the American Association for the Advancement of Science . He has published more than 600 peer-reviewed papers and reviews and is the author or editor of 18 books.
Gil Omenn's Published Works
Published Works
- A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. (1995) (3845)
- Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. (1996) (3479)
- ProteomeXchange provides globally co-ordinated proteomics data submission and dissemination (2014) (2398)
- Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression (2009) (1988)
- Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. (2002) (1883)
- Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. (1996) (1209)
- Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly‐available database (2005) (766)
- A common open representation of mass spectrometry data and its application to proteomics research (2004) (764)
- Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concordances for alcoholism and its biological end points by zygosity among male veterans. (1981) (445)
- A High-Confidence Human Plasma Proteome Reference Set with Estimated Concentrations in PeptideAtlas* (2011) (428)
- The Beta-Carotene and Retinol Efficacy Trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements. (2004) (386)
- Total serum cholesterol levels and mortality risk as a function of age. A report based on the Framingham data. (1993) (361)
- An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: Sensitivity and specificity analysis (2005) (358)
- Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data (2012) (339)
- Beneficial six-year outcome of smoking cessation in older men and women with coronary artery disease. Results from the CASS registry. (1988) (335)
- The Human Proteome Project: Current State and Future Direction (2011) (328)
- Evolution of Translational Omics: Lessons Learned and the Path Forward (2013) (319)
- Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study (2006) (309)
- A wellness study of 108 individuals using personal, dense, dynamic data clouds (2017) (296)
- Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (2019) (283)
- FAMILIAL RETICULOENDOTHELIOSIS WITH EOSINOPHILIA. (1965) (283)
- Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype. (2006) (283)
- The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome (2012) (281)
- The beta-carotene and retinol efficacy trial (CARET) for chemoprevention of lung cancer in high risk populations: smokers and asbestos-exposed workers. (1994) (279)
- Meeting Report: Hazard Assessment for Nanoparticles—Report from an Interdisciplinary Workshop (2007) (236)
- Making evolutionary biology a basic science for medicine (2010) (207)
- Proteogenomic Characterization of Endometrial Carcinoma (2020) (194)
- Systematic comparison of the human saliva and plasma proteomes (2009) (194)
- Occurrence of autoantibodies to annexin I, 14-3-3 theta and LAMR1 in prediagnostic lung cancer sera. (2008) (189)
- Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the beta-carotene and retinol efficacy trial (CARET). (2003) (179)
- Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats. (1990) (177)
- Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis (2005) (175)
- Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks (2010) (173)
- Chemoprevention of lung cancer: the rise and demise of beta-carotene. (1998) (168)
- Preventing coronary heart disease: B vitamins and homocysteine. (1998) (167)
- Human Proteinpedia enables sharing of human protein data (2008) (164)
- The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays. (2017) (156)
- ConceptGen: a gene set enrichment and gene set relation mapping tool (2010) (155)
- The association between lung and prostate cancer risk, and serum micronutrients: results and lessons learned from beta-carotene and retinol efficacy trial. (2003) (154)
- Blood metabolome predicts gut microbiome α-diversity in humans (2019) (151)
- The messenger under attack -- intimidation of researchers by special-interest groups. (1997) (150)
- miRmine: a database of human miRNA expression profiles (2017) (148)
- Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry data (2005) (145)
- Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. (2016) (144)
- Strategy and planning for chemopreventive drug development: Clinical development plans II (1994) (141)
- The Human Proteome Organization Plasma Proteome Project pilot phase: Reference specimens, technology platform comparisons, and standardized data submissions and analyses (2004) (140)
- Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. (2004) (138)
- Metrics for the Human Proteome Project 2013-2014 and strategies for finding missing proteins. (2014) (138)
- Standard guidelines for the chromosome-centric human proteome project. (2012) (136)
- NGSQC: cross-platform quality analysis pipeline for deep sequencing data (2010) (134)
- Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer* (2009) (134)
- Information value of the rodent bioassay (1988) (131)
- Hyperparathyroidism associated with malignant tumors of nonparathyroid origin (1969) (131)
- Novel gene and gene model detection using a whole genome open reading frame analysis in proteomics (2006) (130)
- Intact-protein-based High-resolution Three-dimensional Quantitative Analysis System for Proteome Profiling of Biological Fluids* (2005) (129)
- State of the human proteome in 2013 as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project. (2014) (128)
- Restricted activity days among older adults. (1992) (118)
- Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. (2021) (118)
- Personalized Exposure Assessment: Promising Approaches for Human Environmental Health Research (2005) (116)
- Grand Challenges and Great Opportunities in Science, Technology, and Public Policy (2006) (110)
- The association of Waardenburg syndrome and Hirschsprung megacolon. (1979) (108)
- Medicine Needs Evolution (2006) (107)
- Older adults and smoking. (1992) (105)
- Current perspective on the global and United States cancer burden attributable to lifestyle and environmental risk factors. (2013) (103)
- Characterization of KRAS rearrangements in metastatic prostate cancer. (2011) (102)
- Proteogenomic characterization of pancreatic ductal adenocarcinoma (2021) (101)
- Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and corresponding mRNA expression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-beta-Induced epithelial-mesenchymal transition. (2009) (101)
- The biology/disease-driven human proteome project (B/D-HPP): enabling protein research for the life sciences community. (2013) (99)
- A high-stringency blueprint of the human proteome (2020) (98)
- Males and females. (1976) (97)
- Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future (2007) (95)
- Modification of the single tryptophan residue of staphylococcal nuclease by a new mild oxidizing agent. (1970) (94)
- Recommendations for Mass Spectrometry Data Quality Metrics for Open Access Data (Corollary to the Amsterdam Principles)* (2011) (93)
- Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification. (2015) (92)
- Research, innovation, and university-industry linkages. (1980) (92)
- Cost-effectiveness of short-term tests for carcinogenicity (1986) (90)
- Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity (2003) (89)
- Diagnostic evaluation of headache. Impact of computerized tomography and cost-effectiveness. (1980) (89)
- Strategies for plasma proteomic profiling of cancers (2006) (88)
- Predictors of serum selenium in cigarette smokers and the lack of association with lung and prostate cancer risk. (2001) (86)
- COMMITTEE ON THE REVIEW OF OMICS-BASED TESTS FOR PREDICTING PATIENT OUTCOMES IN CLINICAL TRIALS (2012) (86)
- The relative merits of population-based and targeted prevention strategies. (2008) (86)
- CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis (2020) (84)
- A functional annotation of subproteomes in human plasma (2005) (84)
- VO: Vaccine Ontology (2009) (84)
- Epigenetics: relevance and implications for public health. (2014) (83)
- Integrated Expression Profiling and ChIP-seq Analyses of the Growth Inhibition Response Program of the Androgen Receptor (2009) (83)
- Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data (2019) (83)
- A first step toward completion of a genome-wide characterization of the human proteome. (2013) (83)
- Association of food frequency questionnaire estimates of vitamin A intake with serum vitamin A levels. (1988) (82)
- International Electronic Health Record-Derived COVID-19 Clinical Course Profiles: The 4CE Consortium (2020) (81)
- Phosphoglycerate mutase isozyme marker for tissue differentiation in man. (1974) (80)
- Development and validation of sandwich ELISA microarrays with minimal assay interference. (2008) (79)
- An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer (2009) (79)
- The emerging era of genomic data integration for analyzing splice isoform function. (2014) (79)
- Molecular neurobiology. (1983) (78)
- Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer. (2009) (78)
- A proteogenomic portrait of lung squamous cell carcinoma (2021) (77)
- The Carotene and Retinol Efficacy Trial (CARET) to prevent lung cancer in high-risk populations: pilot study with cigarette smokers. (1993) (77)
- Predictors of lung cancer among asbestos-exposed men in the {beta}-carotene and retinol efficacy trial. (2005) (76)
- A wide range of protein isoforms in serum and plasma uncovered by a quantitative intact protein analysis system (2005) (76)
- State of the Human Proteome in 2014/2015 As Viewed through PeptideAtlas: Enhancing Accuracy and Coverage through the AtlasProphet. (2015) (76)
- Systematically Differentiating Functions for Alternatively Spliced Isoforms through Integrating RNA-seq Data (2013) (74)
- Biotechnology and Biodegradation (1990) (72)
- Congenital adrenal hyperplasia. II. Cognitive and behavioral studies (1975) (72)
- The protective effect of beta-carotene and retinol on ventilatory function in an asbestos-exposed cohort. (1997) (70)
- Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications. (2016) (69)
- Mucin glycosylation is altered by pro-inflammatory signaling in pancreatic-cancer cells. (2009) (68)
- Immunology and genetics of type 1 diabetes. (2008) (68)
- Statistical design and monitoring of the Carotene and Retinol Efficacy Trial (CARET). (1993) (67)
- International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium (2020) (66)
- HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses (2013) (65)
- Analysis of Tumor-Host Interactions by Gene Expression Profiling of Lung Adenocarcinoma Xenografts Identifies Genes Involved in Tumor Formation (2005) (65)
- Humoral Response Profiling Reveals Pathways to Prostate Cancer Progression*S (2008) (64)
- Considering the Case for Vitamin B12 Fortification of Flour (2010) (64)
- Predictive identification of hypersusceptible individuals. (1982) (64)
- Exploring the Human Plasma Proteome (2005) (63)
- Proteomic characterization of novel alternative splice variant proteins in human epidermal growth factor receptor 2/neu-induced breast cancers. (2010) (62)
- Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. (2018) (61)
- New and improved proteomics technologies for understanding complex biological systems: Addressing a grand challenge in the life sciences (2012) (61)
- The association between participant characteristics and serum concentrations of beta-carotene, retinol, retinyl palmitate, and alpha-tocopherol among participants in the Carotene and Retinol Efficacy Trial (CARET) for prevention of lung cancer. (1996) (58)
- Alternative Splice Variants, a New Class of Protein Cancer Biomarker Candidates: Findings in Pancreatic Cancer and Breast Cancer with Systems Biology Implications (2010) (58)
- Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project (2005) (57)
- Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project. (2015) (55)
- Evolution and public health (2009) (55)
- Identifying Inhibitors of Epithelial-Mesenchymal Transition by Connectivity Map–Based Systems Approach (2011) (55)
- Coupled Global and Targeted Proteomics of Human Embryonic Stem Cells during Induced Differentiation*S (2008) (55)
- Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0 (2019) (55)
- Development of data representation standards by the human proteome organization proteomics standards initiative (2015) (54)
- Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice (2003) (53)
- Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project. (2017) (53)
- The Carotene and Retinol Efficacy Trial (CARET) to prevent lung cancer in high-risk populations: pilot study with asbestos-exposed workers. (1993) (53)
- Proteomic Interrogation of Androgen Action in Prostate Cancer Cells Reveals Roles of Aminoacyl tRNA Synthetases (2009) (52)
- Do we want our data raw? Including binary mass spectrometry data in public proteomics data repositories (2005) (52)
- Identification, characterization, and control of potential human carcinogens: a framework for Federal decision-making. (1980) (51)
- Proteomics Approaches to Identify Tumor Antigen Directed Autoantibodies as Cancer Biomarkers (2004) (51)
- The effect of long-term beta-carotene and vitamin A administration on serum concentrations of alpha-tocopherol. (1994) (50)
- Contribution of environmental fibers to respiratory cancer. (1986) (49)
- Ontology-Based Combinatorial Comparative Analysis of Adverse Events Associated with Killed and Live Influenza Vaccines (2012) (49)
- Functional implications of structural predictions for alternative splice proteins expressed in Her2/neu-induced breast cancers. (2011) (48)
- Physical activity in relation to all-site and lung cancer incidence and mortality in current and former smokers. (2004) (48)
- Who holds the stakes? A case study of stakeholder identification at two nuclear weapons production sites (1995) (48)
- A common uptake system for serotonin and dopamine in human platelets. (1978) (48)
- Restricted variation in the glycolytic enzymes of human brain and erythrocytes. (1973) (48)
- A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury. (2007) (48)
- Regulation of the Human Endogenous Retrovirus K (HML-2) Transcriptome by the HIV-1 Tat Protein (2014) (47)
- Advancement of Biomarker Discovery and Validation through the HUPO Plasma Proteome Project (2004) (47)
- Isolation of Mutants of Staphylococcus aureus Lacking Extracellular Nuclease Activity (1970) (47)
- Evolutionary molecular medicine (2012) (47)
- Psychosocial predictors of outcome in a worksite smoking cessation program. (1989) (46)
- Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework (2017) (46)
- The human proteome – a scientific opportunity for transforming diagnostics, therapeutics, and healthcare (2012) (45)
- Healthcare information technology and economics (2013) (45)
- Future research directions in cancer ecogenetics. (1991) (45)
- Implications of DRGs for clinicians. (1984) (44)
- Chemoprevention of lung cancer: the beta-Carotene and Retinol Efficacy Trial (CARET) in high-risk smokers and asbestos-exposed workers. (1996) (43)
- Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer. (2013) (42)
- Environmental Biotechnology. Reducing Risks from Environmental Chemicals Through Biotechnology. Basic Life Sciences Vol. 45 (1988) (42)
- Progress on Identifying and Characterizing the Human Proteome: 2018-2019 Metrics from the HUPO Human Proteome Project. (2019) (41)
- What accounts for the association of vegetables and fruits with lower incidence of cancers and coronary heart disease? (1995) (41)
- Species Differences in Serum Paraoxonase Correlate with Sensitivity to Paraoxon Toxicity (1987) (41)
- A new class of protein cancer biomarker candidates: differentially expressed splice variants of ERBB2 (HER2/neu) and ERBB1 (EGFR) in breast cancer cell lines. (2014) (41)
- Proteomics, human proteome project, and chromosomes. (2011) (41)
- Clinical development plans for cancer chemopreventive agents (1996) (41)
- The degree of roentgenographic parenchymal opacities attributable to smoking among asbestos-exposed subjects. (1990) (40)
- Correlation between respiratory symptoms and pulmonary function in asbestos-exposed workers. (1993) (40)
- THE HUPO Human Plasma Proteome Project (2007) (39)
- Immunochemical localization of parathyroid hormone in cancer tissue from patients with ectopic hyperparathyroidism. (1974) (39)
- A randomized comparison of Worksite-sponsored smoking cessation programs. (1988) (39)
- Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K–Related Sequences (2015) (39)
- EVOLUTION AND MEDICINE IN UNDERGRADUATE EDUCATION: A PRESCRIPTION FOR ALL BIOLOGY STUDENTS (2012) (39)
- Ectopic hormone syndromes associated with tumors in childhood. (1971) (39)
- Fractionation of Antibodies against Staphylococcal Nuclease on ‘Sepharose’ Immunoadsorbents (1970) (39)
- Toward more transparent and reproducible omics studies through a common metadata checklist and data publications. (2014) (39)
- Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetes. (2010) (38)
- Congenital adrenal hyperplasia. I. Family studies of IQ (1975) (38)
- What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask (2021) (38)
- A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. (2013) (38)
- Genetic variability in responses to chemical exposure (1984) (38)
- Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function. (2018) (38)
- Epithelial-mesenchymal transition-associated secretory phenotype predicts survival in lung cancer patients. (2014) (37)
- Computed tomography in patients with cerebrovascular disease: impact of a new technology on patient care. (1978) (37)
- Micronutrients (vitamins and minerals) as cancer-preventive agents. (1996) (37)
- “Topological Significance” Analysis of Gene Expression and Proteomic Profiles from Prostate Cancer Cells Reveals Key Mechanisms of Androgen Response (2010) (37)
- The strategy, organization, and progress of the HUPO Human Proteome Project. (2014) (36)
- HUMAN PHOSPHOGLYCERATE MUTASE: ISOZYME MARKER FOR MUSCLE DIFFERENTIATION AND FOR NEOPLASIA (1975) (36)
- Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes. (2014) (36)
- Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (2020) (36)
- Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program (2019) (35)
- Standards for plasma and serum proteomics in early cancer detection: a needs assessment report from the national institute of standards and technology--National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18-19, 2005. (2006) (35)
- Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles) (2012) (35)
- Genetic Control of Environmental Pollutants (1984) (35)
- Usher syndrome in four hard-of-hearing siblings. (1978) (35)
- Occupational hazards to health care workers: report of a conference. (1984) (35)
- Fossil porphyrins: uncomplexed chlorins in a triassic sediment (1961) (34)
- Dyslexia: search for phenotypic and genetic heterogeneity. (1978) (34)
- The temporal pattern of reduction of mortality risk after smoking cessation. (1990) (34)
- SRM targeted proteomics in search for biomarkers of HCV‐induced progression of fibrosis to cirrhosis in HALT‐C patients (2012) (33)
- The histocompatibility system and human disease. (1976) (32)
- Ectopic polypeptide hormone production by tumors. (1970) (32)
- Dermatomyositis and malignant effusions: rare manifestations of carcinoma of the prostate. (1968) (32)
- Prenatal prediction in myotonic dystrophy: Guidelines for genetic counseling (1973) (32)
- Prospects for radiographic intrauterine diagnosis--the syndrome of thrombocytopenia with absent radii. (1973) (31)
- The role of the histone H3 variant CENPA in prostate cancer (2020) (31)
- Advances and Utility of the Human Plasma Proteome. (2021) (31)
- Metab2MeSH: annotating compounds with medical subject headings (2012) (31)
- Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. (2013) (31)
- Evidence for excess colorectal cancer incidence among asbestos-exposed men in the Beta-Carotene and Retinol Efficacy Trial. (2005) (31)
- Revisiting the identification of canonical splice isoforms through integration of functional genomics and proteomics evidence (2014) (31)
- Auditory and Visual Evoked Responses in Children with Familial Reading Disabilities (1977) (31)
- Genetic issues in the syndrome of minimal brain dysfunction. (1973) (30)
- Discovery of cancer biomarkers through the use of mouse models. (2007) (30)
- Research on The Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, according to the HUPO Human Proteome Project. (2020) (30)
- Genome-Wide Functional Annotation of Human Protein-Coding Splice Variants Using Multiple Instance Learning. (2016) (29)
- Potential clinical and economic effects of homocyst(e)ine lowering. (2000) (29)
- Stopping the active intervention: CARET. (2003) (29)
- Electrocardiogram changes suggestive od coronary artery disease in pneumothorax. Their reversibility with upright posture. (1970) (29)
- Public health genetics: an emerging interdisciplinary field for the post-genomic era. (2000) (29)
- A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data (2008) (29)
- Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans (2015) (29)
- Lobe of origin and histologic type of lung cancer associated with asbestos exposure in the Carotene and Retinol Efficacy Trial (CARET). (1997) (29)
- Functional Networks of Highest-Connected Splice Isoforms: From The Chromosome 17 Human Proteome Project. (2015) (28)
- Risk Estimation and Value‐of‐Information Analysis for Three Proposed Genetic Screening Programs for Chronic Beryllium Disease Prevention (2000) (28)
- Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals. (2019) (28)
- The CARET asbestos-exposed cohort: baseline characteristics and comparison to other asbestos-exposed cohorts. (1997) (27)
- Prevention and the reforming U.S. health care system: changing roles and responsibilities for public health. (1996) (27)
- Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome (2020) (27)
- Chemoprevention of lung cancer is proving difficult and frustrating, requiring new approaches. (2000) (27)
- Prevention and the elderly: appropriate policies. (1990) (26)
- Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas (2017) (26)
- A BIOCHEMICAL AND GENETIC APPROACH TO ALCOHOLISM (1972) (26)
- Genome-wide proteomics, Chromosome-Centric Human Proteome Project (C-HPP), part II. (2014) (25)
- CARET, the β‐carotene and retinol efficacy trial to prevent lung cancer in asbestos‐exposed workers and in smokers (1991) (25)
- Accurate prediction of personalized olfactory perception from large-scale chemoinformatic features (2017) (25)
- 7th HUPO World Congress of Proteomics: Launching the Second Phase of the HUPO Plasma Proteome Project (PPP‐2) 16–20 August 2008, Amsterdam, The Netherlands (2009) (25)
- International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries (2021) (25)
- Nucleome Analysis Reveals Structure–Function Relationships for Colon Cancer (2017) (25)
- Comparisons of serotonin uptake by blood platelets and brain synaptosomes (1978) (25)
- Structure and Protein Interaction-Based Gene Ontology Annotations Reveal Likely Functions of Uncharacterized Proteins on Human Chromosome 17. (2018) (24)
- Beneficial Six-Year Outcome of Smoking Cessation in Older Men and Women with Coronary Artery (1989) (24)
- Evolving phenotypes of non-hospitalized patients that indicate long COVID (2021) (24)
- Cellular, transcriptomic and isoform heterogeneity of breast cancer cell line revealed by full-length single-cell RNA sequencing (2020) (23)
- Effect of shellfish consumption on cholesterol absorption in normolipidemic men. (1987) (23)
- Tiered Human Integrated Sequence Search Databases for Shotgun Proteomics. (2016) (23)
- Changes in cholesterol and triglyceride concentrations in the Vanguard population of the Carotene and Retinol Efficacy Trial (CARET) (2005) (23)
- A mouse plasma peptide atlas as a resource for disease proteomics (2008) (23)
- Streamlining IRB review in multisite trials through single-study IRB Cooperative Agreements: experience of the Beta-Carotene and Retinol Efficacy Trial (CARET). (2002) (22)
- Participation and adherence among older men and women recruited to the Beta-Carotene and Retinol Efficacy trial (CARET). (1991) (22)
- Advances in the Chromosome-Centric Human Proteome Project: looking to the future (2017) (22)
- BiomarkerDigger: A versatile disease proteome database and analysis platform for the identification of plasma cancer biomarkers (2009) (22)
- Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients. (2016) (22)
- Overview of the symposium on public health significance of genomics and eco-genetics. (2010) (22)
- Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications (2013) (22)
- Identifying the Zoonotic Origin of SARS-CoV-2 by Modeling the Binding Affinity between the Spike Receptor-Binding Domain and Host ACE2 (2020) (22)
- Physical, morphological, and chemical studies of dusts derived from the machining of composite-epoxy materials. (1988) (22)
- Long-term vitamin A does not produce clinically significant hypertriglyceridemia: results from CARET, the beta-carotene and retinol efficacy trial. (1994) (21)
- Predictions of rodent carcinogenicity testing results: Interpretation in light of the lave‐omenn value‐of‐information model (1995) (21)
- Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. (2015) (21)
- Linking MedDRA®-Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors (2016) (21)
- Highlights of the Biology and Disease-driven Human Proteome Project, 2015-2016. (2016) (21)
- Negative ion mass spectra of benzene, naphthalene, and anthracene. A new technique for obtaining relatively intense and reproducible negative ion mass spectra. (1968) (20)
- WaveletQuant, an improved quantification software based on wavelet signal threshold de-noising for labeled quantitative proteomic analysis (2010) (20)
- Immunochemistry of staphylococcal nuclease. I. Physical, enzymatic, and immunological studies of chemically modified derivatives. (1970) (20)
- Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project. (2021) (20)
- Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data (2021) (20)
- Stunted Lives, Stagnant Economies: Poverty, Disease, and Underdevelopment (1998) (20)
- Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods (2018) (20)
- Putting environmental risks in a public health context. (1996) (20)
- Inborn errors of metabolism: Clues to understanding human behavioral disorders (1976) (19)
- Prenatal diagnosis of genetic disorders. (1978) (19)
- A Network of Splice Isoforms for the Mouse (2016) (19)
- A Blinded Testing of Function Annotation for uPE1 Proteins by the I-TASSER/COFACTOR Pipeline Using the 2018-2019 Additions to neXtProt and the CAFA3 Challenge. (2019) (19)
- Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam Principles). (2012) (19)
- GENETIC APPROACHES TO THE SYNDROME OF MINIMAL BRAIN DYSFUNCTION * (1973) (19)
- Caring for the community: the role of partnerships. (1999) (19)
- Rapid molecular assays to study human centromere genomics (2017) (19)
- Functions of Essential Genes and a Scale-Free Protein Interaction Network Revealed by Structure-Based Function and Interaction Prediction for a Minimal Genome. (2021) (19)
- Interpretations of the Linxian vitamin supplement chemoprevention trials. (1998) (19)
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- Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma (2022) (0)
- Pulmonary Infection by PCR in Very Low Birth Weight Neonates with Bronchopulmonary Dysplasia or Mikity Wilson Syndrome Comparative Proteomic Analyses of Normal and Normal Pressure Hydrocephalus in Human Cerebrospinal Fluid (2006) (0)
- Evolutionary molecular medicine (2012) (0)
- Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program (2019) (0)
- Gene Expression–Based Tests Developed at Duke University and Used in Clinical Trials (2012) (0)
- Genetic control of environmental pollutants: A conference review (1986) (0)
- Genetic control of environmental pollutants. Basic Life Sciences Volume 28 (1984) (0)
- Genetic variation in susceptibility as a key parameter in risk assessment and risk communication: policy aspects. (1996) (0)
- A human plasma proteome in the PeptideAtlas with estimated protein concentrations (2009) (0)
- Autoantigen IA-2 Heightens the Risk of Type 1 Diabetes Humoral Autoimmunity against the Extracellular Domain of the Neuroendocrine (2010) (0)
- Book Reviews: PROTEOMICS IN DRUG RESEARCH. (2007) (0)
- Health status and its deter minants in urban populations (1998) (0)
- Commentary--medical technologies: a perspective of the Carter administration. (1980) (0)
- General Discussion: Environmental Toxicants (1984) (0)
- Charles A. Dana Foundation Awards in health (1991) (0)
- 502 ASSOCIATION OF DELETERIOUS DUOX2 VARIANTS WITH A PRECLINICAL HALLMARK OF DISTURBED MICROBIOTA-IMMUNE HOMEOSTASIS AND RISK OF INFLAMMATORY BOWEL DISEASE (2021) (0)
- Pharmacogenetics (1982) (0)
- Using Departments of Pathology And (2011) (0)
- A new framework for host-pathogen interaction research (2022) (0)
- Book ReviewRegulating Health Care: The struggle for control (1981) (0)
- A scientific basis for safety (2004) (0)
- Ecogenetics, Evolutionary Biology and Human Disease (2007) (0)
- Chromosome 17: neXt-MP50 C-HPP Challenge Completed (2019) (0)
- Lowering total cholesterol level in the older adult raises serious questions (1994) (0)
- Promoting healthy behavior: How much freedom? Whose responsibility? Daniel Callahan, editor, Washington DC: Georgetown University Press, 2000. 192 pages; $19.95 (2001) (0)
- A healthier America: health promotion and disease prevention objectives for the year 2000. (1990) (0)
- DRGs and hospital readmissions. (1985) (0)
- Studies of serum thyroxine-binding globulin (TBG). (1971) (0)
- A systems pharmacology approach to model tyrosine kinase inhibitor‐induced cardiotoxicity gene interaction networks (844.17) (2014) (0)
- Regulatory frameworks and decisions matter to the development of biotechnology and the approvals for biotechnology products. (1999) (0)
- Summary of the work group on reproductive effects (1984) (0)
- Preventive medicine and public health: preventing low birth weight. (1985) (0)
- Strategies for Genomic and Proteomic Profiling of Cancers (2014) (0)
- INTRODUCTION (1972) (0)
- Identification of autoantibodies to tumor-derived antigens as candidate biomarkers for the early detection of lung cancer (2005) (0)
- Cholesterol screening and cholesterol-lowering regimens examined. (1993) (0)
- CRESP at one year (1996) (0)
- Engineering: lessons from medical schools. (1982) (0)
- Is science sexist (1982) (0)
- HUPO 3rd annual World Congress on Proteomics. 25-27th October, 2004, Beijing, China. (2005) (0)
- Preface by the Gilbert S. Omenn (1990) (0)
- Abstract 3127: Comprehensive proteogenomic characterization of rare kidney tumors (2023) (0)
- Editorial: The Human Genome Project (1990) (0)
- Fabry's Disease: TheSearchfora Regulator GeneMutation inMan (1972) (0)
- Basic Life Sciences. Volume 28. Genetic Control of Environmental Pollutants, Proceedings of a Conference Held at Seattle, Washington on 31 July-3 August 1983, (1984) (0)
- Research Universities and the Future: Challenges and Opportunities (2019) (0)
- 60P Association between food frequency questionnaire estimates and serum concentrations of β-carotene, retinol, retinyl palmitate, and α-tocopherol among participants in the caret lung cancer chemoprevention trial (1994) (0)
- INTRODUCTION (1972) (0)
- RESPONSE: Chemoprevention or Antichemo- prevention? A Salutary Warning From the β-Carotene Experience (2001) (0)
- Genetics and Genomics of Neurobehavioral Disorders.Contemporary Clinical Neuroscience.Edited byGene S Fisch.Totowa (New Jersey): Humana Press. $125.00. x + 428 p; ill.; index. ISBN: 1–58829–045–X. 2003. (2003) (0)
- Preface by Gilbert S. Omenn (1993) (0)
- VO Modeling and Comparison of Vaccines (2009) (0)
- Session 19: Plasma Proteomics I (2004) (0)
- Proceed with caution: Predicting genetic risks in the recombinant DNA era (1990) (0)
- Pneumococcal antibodies in older tobacco smokers indicate naturally acquired immuntiy (1996) (0)
- Medicare's new payment plan (1985) (0)
- Introduction: Symposium on Selected Clinical Syndromes Associated with Aging (1992) (0)
- Multiplexed detection of protein and phosphorylation variation in response to androgen withdrawal in LNCaP cells (2007) (0)
- Symposium On Selected Clinical Syndromes Associated With Aging (1992) (0)
- Basic research as an investment in the future. (1985) (0)
- A Quest for Missing Proteins: update 2015 on Chromosome-Centric Human (2015) (0)
- The ß-Caroteneand Retinol Efficacy Trial (CARET) for Chemoprevention of Lung Cancer in High Risk Populations: Smokers and Asbestos-exposed Workers1 (2006) (0)
- Abstract 2214: An integrative approach to reveal driver gene fusions from paired end sequencing data in cancer (2010) (0)
- Highlights of the HUPO Plasma Proteome Project: Creating a knowledge base for clinical assays (2005) (0)
- Evaluation of Omics-Based Tests for Clinical Utility and Use (2012) (0)
- Standard Guidelines for the Chromosome-Centric (2012) (0)
- Blood metabolome predicts gut microbiome α-diversity in humans (2019) (0)
- List of contributors (1986) (0)
- Putting patients and families first. (2000) (0)
- HANCOCK WS. GENOME-WIDE PROTEOMICS, CHROMOSOMECENTRIC HUMAN PROTEOME PROJECT (C-HPP), PART II (2014) (0)
- Book Review:Regulatory Toxicology. Christopher P. Chengelis, Joseph F. Holson, Shayne C. Gad (1996) (0)
- FIFTH INTERNATIONAL CONGRESS OF HUMAN GENETICS: DNA/RNA hybridization studies (1976) (0)
- Report on the World Health Organization's ''Public Health Summit'' (1991) (0)
- INTRODUCTION (1972) (0)
- PUBLIC COMMENT ON OMB DRAFT RISK ASSESSMENT BULLETIN (2006) (0)
- Introduction to Biomarkers (2012) (0)
- Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness. (2022) (0)
- Modeling Dynamic Fluctuations in Type 1 Diabetes Progression: Quantifying β -cell variation after the appearance of islet-specific autoimmune responses (2015) (0)
- Evaluation of Headache-Reply (1981) (0)
- Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework (2017) (0)
- Abstract 5118: Proteogenomics characterization of HPV-negative head and neck squamous cell carcinomas (2020) (0)
- The Politics of Health Care (1980) (0)
- Molecular neurogenetics (1981) (0)
- Letter from Gilbert S. Omenn, Risk Assessment and Risk Management Commission (RAMC) to Thomas S. Foley (1997) (0)
- Molecular Neurobiology: Molecular Approaches to Neurobiology . Ian R. Brown, Ed. Academic Press, New York, 1982. xii, 422 pp., illus. $49.50. Cell Biology. (1983) (0)
- Prognostic Factors in Cancer, 3rd edition. By M. K. Gospodarowicz, B. O'Sullivan, L. H. Sobin (Eds.) (2006) (0)
- Policy aspects of epidemiologic studies of possible health effects of electric and magnetic fields from power lines. (1991) (0)
- Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans (2015) (0)
- INTRODUCTION (1972) (0)
- INTRODUCTION (1972) (0)
- Health services for tomorrow: Trends & issues: by Eveline M. Burns. Dunellen Publishing, New York, 1973. 226 pp. $5.95 (paper). (1977) (0)
- Effects of Chronic Excess Salt Feeding: Demonstration of Normal Thyroid Function in Salt-Fed Dogs with Hypercholesterolemia 1 (1970) (0)
- Adrenals in Ectopic ACTH Syndrome (1971) (0)
- Book ReviewGenetics of Neurological and Psychiatric Disorders The Genetics of Neurological Disorders (1983) (0)
- Contents, Vol. 5, 1974 (1971) (0)
- Abstract LB-52: Integrative protein and transcriptomic analysis identified an EMT-associated secretory phenotype that correlates with metastasis and predicts survival in lung adenocarcinoma patients (2011) (0)
- Users and Providers of the New Technologies (1988) (0)
- N-Glycoproteomic Landscape of Human Lymphoid Cancers Reveals Novel Biomarkers and Potential Therapeutic Targets (2015) (0)
- Book Review: Promoting Healthy Behavior: How Much Freedom? Whose Responsibility? (2001) (0)
- Information Gathering Sessions and Speakers (2012) (0)
- Heredity and environmental interactions. (1987) (0)
- Abstract 2305: Identifying inhibitors of Epithelial-mesenchymal transition to prevent metastasis using global gene expression profile and a systems biology tool (2010) (0)
- Ectopic pth production. (1970) (0)
- What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask (Preprint) (2020) (0)
- HUMAN BEHAVIOR, GENES AND SOCIETY (1972) (0)
- Committee Member and Staff Biographies (2012) (0)
- Modeling the functional relationship network at the isoform level through heterogeneous data integration (2014) (0)
- Genetics and alcoholism. Research strategies. (1987) (0)
- Federal Policy Making for Biotechnology Executive Branch Office of Management and Budget (2002) (0)
- Genomics and public health (2005) (0)
- Familial reticuloendotheliosis with eosinophilia: a follow-up. (1971) (0)
- P95 Human subjects review in long-term prevention trials: Recommendations from the caret experience (1997) (0)
- In the Limelight (2001) (0)
- Biomarker Discovery for Metastatic Disease (2009) (0)
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