Huda Akil | Academic Influence

Huda Akil's AcademicInfluence.com Rankings

Huda Akil

Biology

#1163

World Rank

#1979

Historical Rank

Neuroscience

#117

World Rank

#124

Historical Rank

biology Degrees

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Biology

Huda Akil's Degrees

PhD Neuroscience University of California, Irvine
Doctorate Medicine University of California, Irvine

Why Is Huda Akil Influential?

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According to Wikipedia, Huda Akil is a Syrian–American neuroscientist whose pioneering research has contributed to the understanding of the neurobiology of emotions, including pain, anxiety, depression, and substance abuse. Akil and colleagues are best known for providing the first physiological evidence for a role of endorphins in the brain and demonstrating that endorphins are activated by stress and can cause pain inhibition.

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Huda Akil's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data (2005) (1891)
Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications (1995) (1243)
Endogenous opioids: biology and function. (1984) (1200)
Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. (1991) (1199)
Anatomy of CNS opioid receptors (1988) (1140)
Pattern and time course of immediate early gene expression in rat brain following acute stress (1995) (1047)
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 (2011) (929)
Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization study (1994) (812)
Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain (1987) (778)
Analgesia from Electrical Stimulation in the Brainstem of the Rat (1971) (736)
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist (1976) (657)
A selective role for dopamine in reward learning (2010) (602)
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression (2005) (571)
Stress-induced parallel changes in central opioid levels and pain responsiveness in the rat (1977) (556)
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction (2009) (502)
Cloning and pharmacological characterization of a rat μ opioid receptor (1993) (501)
Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis (1990) (481)
Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo-pituitary-adrenocortical axis (1989) (475)
Circadian patterns of gene expression in the human brain and disruption in major depressive disorder (2013) (464)
Pain reduction by electrical brain stimulation in man. Part 2: Chronic self-administration in the periventricular gray matter. (1977) (423)
Cloning and pharmacological characterization of a rat kappa opioid receptor. (1993) (420)
Pain reduction by electrical brain stimulation in man. Part 1: Acute administration in periaqueductal and periventricular sites. (1977) (415)
Evidence for two separate opiate peptide neuronal systems (1978) (415)
Dynorphin and vasopressin: common localization in magnocellular neurons. (1982) (414)
Anatomy of an Endogenous Antagonist: Relationship between Agouti-Related Protein and Proopiomelanocortin in Brain (1999) (395)
Immunohistochemical localization of the cloned μ opioid receptor in the rat CNS (1995) (389)
Neurobiological Correlates of Individual Differences in Novelty-Seeking Behavior in the Rat: Differential Expression of Stress-Related Molecules (2000) (368)
Dysregulation of the fibroblast growth factor system in major depression. (2004) (367)
Opioid receptor‐like (ORL1) receptor distribution in the rat central nervous system: Comparison of ORL1 receptor mRNA expression with 125I‐[14Tyr]‐orphanin FQ binding (1999) (350)
Neural circuits mediating stress (1999) (345)
Monoaminergic mechanisms of stimulation-produced analgesia (1975) (342)
Delayed effects of chronic variable stress during peripubertal‐juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats (2004) (326)
Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. (1989) (320)
Loss of glucocorticoid fast feedback in depression. (1991) (316)
Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain (2004) (312)
An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction (2010) (312)
Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression (2010) (311)
Behavioral neurochemistry: neuroregulators and behavioral states. (1978) (311)
Dynorphin immunocytochemistry in the rat central nervous system (1982) (311)
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry (2009) (304)
μ-Opioid receptor mRNA expression in the rat CNS: comparison to μ-receptor binding (1994) (290)
Differential Distribution and Regulation of OX1 and OX2 Orexin/Hypocretin Receptor Messenger RNA in the Brain upon Fasting (2000) (288)
Treatment resistant depression: A multi-scale, systems biology approach (2018) (284)
Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor. (1972) (281)
Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats (2007) (278)
Mitochondrial involvement in psychiatric disorders (2008) (278)
Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression (1993) (271)
Distribution of α 1a-, α 1b- and α 1d-adrenergic receptor mRNA in the rat brain and spinal cord (1997) (271)
Comparison of the distribution of dynorphin systems and enkephalin systems in brain. (1982) (265)
Social Stress in Hamsters: Defeat Activates Specific Neurocircuits within the Brain (1997) (261)
Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. (2004) (252)
Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain. (1991) (251)
Neuropeptide Concentrations in the Cerebrospinal Fluid of Depressed Patients Treated with Electroconvulsive Therapy (1991) (248)
Individual differences in the attribution of incentive salience to a reward-related cue: Influence on cocaine sensitization (2008) (242)
Distinct neurochemical populations in the rat central nucleus of the amygdala and bed nucleus of the stria terminalis: Evidence for their selective activation by interleukin‐1β (1999) (240)
Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. (2004) (240)
Controlling signaling with a specifically designed Gi-coupled receptor. (1998) (239)
The cloned μ, δ and κ receptors and their endogenous ligands: Evidence for two opioid peptide recognition cores (1995) (231)
Nonopiate effects of dynorphin and des-Tyr-dynorphin. (1982) (231)
Amphetamine-Induced Behavior, Dopamine Release, and c-fos mRNA Expression: Modulation by Environmental Novelty (1998) (230)
Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain A. Mansour H. Khachaturian, M.E. Lewis, H. Akil and S.J. Watson, Neuroscience, 7 (1987) 2445–2464 (1988) (223)
Immunocytochemical localization of methionine enkephalin: preliminary observations. (1977) (222)
The Neuroscience Information Framework: A Data and Knowledge Environment for Neuroscience (2008) (220)
Interaction between α-Melanocyte-Stimulating Hormone and Corticotropin-Releasing Hormone in the Regulation of Feeding and Hypothalamo-Pituitary-Adrenal Responses (2003) (219)
Gender-Specific Gene Expression in Post-Mortem Human Brain: Localization to Sex Chromosomes (2004) (217)
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
Contribution of the Ventral Subiculum to Inhibitory Regulation of the Hypothalamo‐Pituitary‐Adrenocortical Axis (1995) (205)
Characterization of opioid agonist efficacy in a C6 glioma cell line expressing the mu opioid receptor. (1996) (202)
Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice (2007) (202)
Mineralocorticoid receptor function in major depression. (2003) (202)
Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2009) (201)
Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation H. Akil, D.E. Richardson, J. Hughes and J.D. Barchas, Science, 201 (1978) 463–465 (1978) (199)
Selective Breeding for Divergence in Novelty-seeking Traits: Heritability and Enrichment in Spontaneous Anxiety-related Behaviors (2006) (194)
Revisiting the Stress Concept: Implications for Affective Disorders (2020) (194)
Frontal and Limbic Activation During Inhibitory Control Predicts Treatment Response in Major Depressive Disorder (2007) (189)
Challenges and Opportunities in Mining Neuroscience Data (2011) (184)
Inhibition of opiate tolerance by non-competitive N-d-aspartate receptor antagonists (1994) (184)
Cellular localization and distribution of the cloned mu and kappa opioid receptors in rat gastrointestinal tract (1997) (183)
Excitatory amino acids and drugs of abuse: a role for N-methyl-D-aspartate receptors in drug tolerance, sensitization and physical dependence. (1995) (179)
Increased evening activation of the hypothalamic-pituitary-adrenal axis in depressed patients. (1994) (175)
Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders (2006) (174)
The Future of Psychiatric Research: Genomes and Neural Circuits (2010) (171)
Endogenous opioids: overview and current issues. (1998) (167)
Appearance of beta-endorphin-like immunoreactivity in human ventricular cerebrospinal fluid upon analgesic electrical stimulation. (1978) (165)
Individual Differences in Cue-Induced Motivation and Striatal Systems in Rats Susceptible to Diet-Induced Obesity (2015) (162)
Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell. (2000) (159)
α-MSH in rat brain: occurence within and outside of β-endorphin neurons (1980) (158)
Site-directed mutagenesis of the human dopamine D2 receptor. (1992) (157)
Rare coding variants in ten genes confer substantial risk for schizophrenia (2022) (154)
Effects of naloxone on schizophrenia: reduction in hallucinations in a subpopulation of subjects. (1978) (153)
Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition. (1991) (153)
The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion (1996) (153)
Evidence that β-endorphin is synthesized in cells in the nucleus tractus solitarius: detection of POMC mRNA (1992) (152)
Relation between the Hypothalamic-Pituitary-Thyroid (HPT) Axis and the Hypothalamic-Pituitary-Adrenal (HPA) Axis during Repeated Stress (2005) (151)
A task to manipulate attentional load, set-shifting, and inhibitory control: Convergent validity and test–retest reliability of the Parametric Go/No-Go Test (2007) (150)
Hormonal Evidence for Altered Responsiveness to Social Stress in Major Depression (2000) (150)
Dynorphin immunocytochemical localization in brain and peripheral nervous system: preliminary studies. (1981) (149)
Immunohistochemical localization of the cloned κ 1 receptor in the rat CNS and pituitary (1996) (146)
Pharmacological and anatomical evidence of selective μ, δ, and χ opioid receptor binding in rat brain (1986) (146)
Opiate binding properties of naturally occurring N- and C-Terminus modified beta-endorphins (1981) (146)
Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. (2003) (145)
Pituitary-Adrenal Response to Ether Vapor in the Weanling Animal: Characterization of the Inhibitory Effect of Glucocorticoids on Adrenocorticotropin Secretion (1993) (144)
Social defeat alters the acquisition of cocaine self-administration in rats: role of individual differences in cocaine-taking behavior (2001) (142)
Long term results of periventricular gray self-stimulation. (1977) (141)
Delta opioid receptor mRNA distribution in the brain: Comparison to delta receptor binding and proenkephalin mRNA (1993) (141)
Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder (2014) (140)
Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal (2002) (140)
A New Role for FGF2 as an Endogenous Inhibitor of Anxiety (2009) (138)
The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats (2008) (137)
Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression (1992) (136)
Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons (1999) (135)
κ1 Receptor mRNA Distribution in the Rat CNS: Comparison to κ Receptor Binding and Prodynorphin mRNA (1994) (134)
Corticotropin-releasing factor stimulation of adrenocorticotropin and beta-endorphin release: effects of acute and chronic stress. (1985) (133)
The Fibroblast Growth Factor Family: Neuromodulation of Affective Behavior (2012) (133)
The effects of footshock stress on regional brain dopamine metabolism and pituitary β-endorphin release in rats previously sensitized to amphetamine (1987) (131)
Persistent Alterations in Cognitive Function and Prefrontal Dopamine D2 Receptors Following Extended, but Not Limited, Access to Self-Administered Cocaine (2008) (129)
Direct evidence of nitric oxide presence within mitochondria. (2000) (129)
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia (2017) (129)
Differential pattern of c-fos mRNA in rat brain following central and systemic administration of interleukin-1-beta: implications for mechanism of action. (1996) (128)
The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans. (1998) (128)
The Fibroblast Growth Factor System and Mood Disorders (2006) (126)
Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat (1996) (125)
Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis * (2002) (123)
Post-mortem molecular profiling of three psychiatric disorders (2016) (122)
Novelty-seeking behavior predicts vulnerability in a rodent model of depression (2011) (121)
Antidepressant-like effects of intracerebroventricular FGF2 in rats (2008) (119)
Amphetamine and cocaine induce different patterns of c‐fos mRNA expression in the striatum and subthalamic nucleus depending on environmental context (2001) (119)
Environmental Novelty Differentially Affects c-fosmRNA Expression Induced by Amphetamine or Cocaine in Subregions of the Bed Nucleus of the Stria Terminalis and Amygdala (2001) (117)
Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty (2014) (115)
Primary astroglial cultures derived from several rat brain regions differentially express μ, δ and κ opioid receptor mRNA (1995) (115)
Methodological considerations for gene expression profiling of human brain (2007) (114)
Nociceptin/orphanin FQ regulates neuroendocrine function of the limbic–hypothalamic–pituitary–adrenal axis (2001) (113)
The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. (1995) (113)
5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus. (1993) (110)
Induction of the intermediate pituitary by stress: synthesis and release of a nonopioid form of beta-endorphin. (1985) (109)
B-ETA-Endorphin immunoreactivity in rat and human blood: radioimmunoassay, comparative levels and physiological alterations. (1979) (107)
Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder. (2013) (107)
Opioid Effects on Mitogen‐activated Protein Kinase Signaling Cascades (1997) (107)
Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. (2013) (107)
Binding of 3H-beta-endorphin to rat brain membranes: characterization of opiate properties and interaction with ACTH. (1980) (106)
Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP mRNA in select populations of neuroendocrine neurons (1989) (105)
Expression of α1b Adrenoceptor mRNA in Corticotropin-Releasing Hormone-Containing Cells of the Rat Hypothalamus and Its Regulation by Corticosterone (1999) (105)
Cushing's syndrome secondary to ectopic corticotropin-releasing hormone-adrenocorticotropin secretion. (1986) (104)
Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity (2010) (104)
Individual differences in novelty-seeking behavior in rats: a c-fos study (2001) (103)
Transcriptional Profiling of the Developing Rat Brain Reveals That the Most Dramatic Regional Differentiation in Gene Expression Occurs Postpartum (2006) (102)
Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens (2001) (102)
Stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding by endogenous opioids acting at a cloned mu receptor. (1998) (101)
The presence of two α-MSH positive cell groups in rat hypothalamus (1979) (100)
Differential binding properties of oripavines at cloned μ- and δ-opioid receptors (1999) (99)
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls (2018) (99)
Estrogen receptor β in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone (2003) (98)
Some observations on the opiate peptides and schizophrenia. (1979) (97)
Mu and kappa opioid receptors in periaqueductal gray and rostral ventromedial medulla (1998) (97)
Expression of c-fos gene activation during rough and tumble play in juvenile rats (2002) (96)
Regulation of hypothalamic magnocellular neuropeptides and their mRNAs in the Brattleboro rat: coordinate responses to further osmotic challenge (1988) (96)
Detection of proopiomelanocortin mRNA by in situ hybridization with an oligonucleotide probe. (1986) (95)
Inhibition of opiate tolerance by non-competitive N-methyl-D-aspartate receptor antagonists. (1994) (95)
Socially-induced brain ‘fertilization’: play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats (2003) (95)
Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia (2020) (94)
Lateral hypothalamic innervation of the cerebral cortex: Immunoreactive staining for a peptide resembling but immunochemically distinct from pituitary/arcuate α-melanocyte stimulating hormone (1986) (94)
A Chimeric Study of the Molecular Basis of Affinity and Selectivity of the κ and the δ Opioid Receptors. (1995) (93)
Opiate tolerance and dependence: recent findings and synthesis. (1991) (93)
Circulating adrenal hormones are not necessary for the development of sensitization to the psychomotor activating effects of amphetamine (1995) (92)
Opioid receptor expression in the rat gastrointestinal tract: a quantitative study with comparison to the brain. (1997) (91)
mu-Opioid receptor mRNA expression in the rat CNS: comparison to mu-receptor binding. (1994) (90)
The 5-HT7 receptor: Role in novel object discrimination and relation to novelty-seeking behavior (2007) (89)
Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake. (2002) (89)
Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals (2011) (87)
β-Endorphin and Schizophrenia (1980) (87)
The critical importance of basic animal research for neuropsychiatric disorders (2019) (87)
c- fos mRNA Induction in Acute and Chronic Audiogenic Stress: Possible Role of the Orbitofrontal Cortex in Habituation (2002) (84)
Nociceptin/orphanin FQ and opioid receptor‐like receptor mRNA expression in dopamine systems (2002) (84)
Effects of morphine treatment on pro-opiomelanocortin systems in rat brain (1990) (83)
Human plasma beta-endorphin-like peptides: a rapid, high recovery extraction technique and validation of radioimmunoassay. (1983) (82)
Pro-dynorphin peptides are found in the same neurons throughout rat brain: immunocytochemical study. (1983) (82)
Hydrophobic Residues of the D2 Dopamine Receptor Are Important for Binding and Signal Transduction (1995) (82)
Environmental context and drug history modulate amphetamine-induced c-fos mrna expression in the basal ganglia, central extended amygdala, and associated limbic forebrain (2003) (81)
Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats (2011) (80)
Stress-induced changes in primate prefrontal profiles of gene expression (2007) (80)
Multiple HPA profiles in endogenous depression: Effect of age and sex on cortisol and beta-endorphin (1993) (79)
Moving from the Orphanin FQ Receptor to an Opioid Receptor Using Four Point Mutations* (1996) (79)
Diurnal corticotropin-releasing hormone mRNA variation in the hypothalamus exhibits a rhythm distinct from that of plasma corticosterone. (1992) (79)
The Role of the Hippocampal Mineralocorticoid and Glucocorticoid Receptors in the Hypothalamo-Pituitary-Adrenal Axis of the Aged Fisher Rat (1994) (79)
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder (2015) (79)
Motivational Properties of Oxytocin in the Conditioned Place Preference Paradigm (1997) (79)
The Many Possible Roles of Opioids and Related Peptides in Stress‐Induced Analgesia a (1986) (78)
Overexpressing the Glucocorticoid Receptor in Forebrain Causes an Aging-Like Neuroendocrine Phenotype and Mild Cognitive Dysfunction (2007) (78)
Stress during adolescence alters behavioral sensitization to amphetamine (2002) (78)
Combining laser capture microdissection with quantitative real-time PCR: Effects of tissue manipulation on RNA quality and gene expression (2006) (77)
Gene Expression Changes in the Prefrontal Cortex, Anterior Cingulate Cortex and Nucleus Accumbens of Mood Disorders Subjects That Committed Suicide (2012) (77)
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms (1994) (77)
Evidence for homologous actions of pro-opiocortin products. (1980) (75)
Dissociation between pituitary and adrenal suppression to dexamethasone in depression. (1993) (74)
Opioid efficacy in a C6 glioma cell line stably expressing the human kappa opioid receptor. (1999) (74)
Evidence for alterations of the glial syncytial function in major depressive disorder. (2016) (73)
Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain (1984) (73)
Behavioral effects of dynorphin1–13 in the mouse and rat: Initial observations (1980) (73)
Characterization of the forms of β-endorphin and α-MSH in the caudal medulla of the rat and guinea pig (1986) (73)
A possible interface between autonomic function and pain control: opioid analgesia and the nucleus tractus solitarius (1987) (72)
Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse (2010) (72)
Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord (1986) (72)
Primary structure and functional expression of a guinea pig kappa opioid (dynorphin) receptor. (1994) (71)
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques (1992) (71)
Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims. (1992) (71)
Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ (1996) (71)
Serotonin transporter mRNA in rat brain is regulated by classical antidepressants (1994) (70)
Expression of orphanin FQ and the opioid receptor-like (ORL1) receptor in the developing human and rat brain (2002) (70)
Diurnal CRH mRNA rhythm in the hypothalamus: decreased expression in the evening is not dependent on endogenous glucocorticoids. (1993) (69)
Pretranslational and posttranslational mechanisms for regulating beta-endorphin-adrenocorticotropin of the anterior pituitary lobe. (1986) (69)
Gene chips and arrays revealed: a primer on their power and their uses (1999) (69)
Prenatal stress does not alter innate novelty-seeking behavioral traits, but differentially affects individual differences in neuroendocrine stress responsivity (2008) (67)
Opioid efficacy in a C6 glioma cell line stably expressing the delta opioid receptor. (1997) (66)
Rostral Elements of Sympatho-motor Circuitry: A Virally Mediated Transsynaptic Tracing Study (2006) (66)
Interleukin‐1β‐Mediated Regulation of μ‐Opioid Receptor mRNA in Primary Astrocyte‐Enriched Cultures (1996) (64)
The degradation of dynorphin A in brain tissue in vivo and in vitro (1987) (63)
The search for the neurobiological basis of vulnerability to drug abuse: using microarrays to investigate the role of stress and individual differences (2004) (62)
The fibroblast growth factor system is downregulated following social defeat (2008) (61)
Opioid receptors: past, present and future (1995) (61)
The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality (1991) (61)
Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA. (1995) (60)
Analysis of 5-HT6 and 5-HT7 receptor gene expression in rats showing differences in novelty-seeking behavior (2007) (60)
Regulation of Hippocampal 5-HT1A Receptor Gene Expression by Dexamethasone (1994) (59)
The interleukin-1β-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte-enriched cultures (1997) (58)
Nitric oxide in the stress axis. (1998) (58)
The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior (2012) (58)
3xTg-AD mice exhibit an activated central stress axis during early-stage pathology. (2012) (58)
Gender‐specific disruptions in emotion processing in younger adults with depression (2009) (58)
Lesions of the Medial Geniculate Nuclei Specifically Block Corticosterone Release and Induction of c-fos mRNA in the Forebrain Associated with Audiogenic Stress in Rats (1997) (57)
High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups (2011) (57)
Immunohistochemical localization of the cloned kappa 1 receptor in the rat CNS and pituitary. (1996) (56)
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors. (1999) (55)
G protein-linked signaling pathways in bipolar and major depressive disorders (2013) (55)
Regulation of striatonigral prodynorphin peptides by dopaminergic agents (1990) (55)
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test (2008) (55)
High novelty-seeking rats are resilient to negative physiological effects of the early life stress (2014) (54)
Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132) (2001) (54)
Constitutive activity of the δ‐opioid receptor expressed in C6 glioma cells: identification of non‐peptide δ‐inverse agonists (1999) (53)
Distinct populations of presympathetic‐premotor neurons express orexin or melanin‐concentrating hormone in the rat lateral hypothalamus (2007) (53)
Individual differences in novelty-seeking and emotional reactivity correlate with variation in maternal behavior (2007) (53)
Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model (2016) (53)
Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disorders. (2016) (53)
Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis (2018) (52)
Kappa 1 receptor mRNA distribution in the rat CNS: comparison to kappa receptor binding and prodynorphin mRNA. (1994) (52)
Stressed and depressed (2005) (52)
Mapping the receptor domains critical for the binding selectivity of δ-opioid receptor ligands (1996) (51)
Temporal and anatomical distribution of nitric oxide synthase mRNA expression and nitric oxide production during central nervous system inflammation (2000) (51)
DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles (2003) (51)
Developmental underpinnings of differences in rodent novelty‐seeking and emotional reactivity (2011) (51)
Short-Hairpin RNA Silencing of Endogenous Fibroblast Growth Factor 2 in Rat Hippocampus Increases Anxiety Behavior (2011) (50)
ENKEPHALIN-LIKE MATERIAL IN NORMAL HUMAN CSF: MEASUREMENT AND LEVELS. (1978) (50)
Differential effects of social defeat in rats with high and low locomotor response to novelty (2011) (50)
The posttranslational processing of prodynorphin in the rat anterior pituitary. (1989) (50)
Glutamate transporters: a key piece in the glutamate puzzle of major depressive disorder. (2013) (50)
The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression. (2016) (50)
The “chip” as a specific genetic tool (2000) (49)
Molecular and Neuroanatomical Properties of the Endogenous Opioid System: Implications for Treatment of Opiate Addiction (1997) (49)
Lesions of the paraventricular nucleus of the thalamus differentially affect sign‐ and goal‐tracking conditioned responses (2015) (48)
Relationship of presympathetic‐premotor neurons to the serotonergic transmitter system in the rat brainstem (2006) (48)
Two precursors of melanin-concentrating hormone: DNA sequence analysis and in situ immunochemical localization. (1989) (47)
The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context (2002) (47)
Opioids and pain regulation. (1987) (47)
A sensitive coupled HPLC RIA technique for separation of endorphins: Multiple forms of B-endorphin in rat pituitary intermediate vs. anterior lobe (1981) (46)
DNA Methylation in the Developing Hippocampus and Amygdala of Anxiety-Prone versus Risk-Taking Rats (2012) (46)
In vitro degradation of enkephalin: evidence for cleavage at the Gly-Phe bond. (1978) (46)
The effects of naloxone in chronic schizophrenia. (1981) (46)
Amphetamine‐induced c‐fos mRNA expression in the caudate‐putamen and subthalamic nucleus: interactions between dose, environment, and neuronal phenotype (2003) (45)
Neuroscience Training for the 21st Century (2016) (45)
Pro-dynorphin is endogenous to the anterior pituitary and is co-localized with LH and FSH in the gonadotrophs. (1986) (45)
FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: Partnership with H3K9me3 (2014) (45)
β-lipotropin-β-endorphin response to low-dose ovine corticotropin releasing factor in endogenous depression : preliminary studies (1990) (45)
Amphetamine‐evoked c‐fos mRNA expression in the caudate‐putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context (2003) (45)
α, β, and γ Mineralocorticoid Receptor Messenger Ribonucleic Acid Splice Variants: Differential Expression and Rapid Regulation in the Developing Hippocampus. (1998) (44)
Prodynorphin peptide immunocytochemistry in rhesus monkey brain (1985) (43)
Diurnal rhythmic expression of the rhythm-related genes, rPeriod1, rPeriod2, and rClock, in the rat brain. (2005) (43)
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop. (2000) (43)
Mitochondrial related gene expression changes are sensitive to agonal-pH state (2006) (42)
Fibroblast growth factor 9 is a novel modulator of negative affect (2015) (42)
Norepinephrine-induced CRH and AVP gene transcription within the hypothalamus: differential regulation by corticosterone. (2001) (42)
A 6-Hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis (2002) (41)
Early-Life Forebrain Glucocorticoid Receptor Overexpression Increases Anxiety Behavior and Cocaine Sensitization (2012) (41)
Distribution of Mahogany/Attractin mRNA in the rat central nervous system (1999) (41)
Orphanin FQ-induced hyperphagia is mediated by corticosterone and central glucocorticoid receptors (2002) (41)
β-Endorphin/β-Lipotropin Immunoreactivity in Endogenous Depression: Effect of Dexamethasone (1986) (40)
Decreased Proliferation of Adult Hippocampal Stem Cells During Cocaine Withdrawal: Possible Role of the Cell Fate Regulator FADD (2011) (40)
Mitochondrial Mutations in Subjects with Psychiatric Disorders (2015) (39)
Enkephalinase: Selective inhibitors and partial characterization (1980) (38)
A Conserved Proline in the hsp90 Binding Region of the Glucocorticoid Receptor Is Required for hsp90 Heterocomplex Stabilization and Receptor Signaling* (1998) (38)
The preferential release of beta-endorphin from the anterior pituitary lobe by Corticotropin Releasing Factor (CRF) (1986) (38)
Endorphins, beta-LPH, and ACTH: biochemical, pharmacological and anatomical studies. (1978) (37)
Induction of analgesia by central administration of ORG 2766, an analog of ACTH4--9. (1981) (37)
3 OPIOID PEPTIDES AND THEIR RECEPTORS : OVERVIEW AND FUNCTION IN PAIN MODULATION (2001) (37)
Altered choroid plexus gene expression in major depressive disorder (2014) (37)
Further characterization of the extra-arcuate alpha-melanocyte stimulating hormone-like material in hypothalamus: Biochemical and anatomical studies (1986) (36)
Sturgeon Orphanin, a Molecular “Fossil” That Bridges the Gap between the Opioids and Orphanin FQ/Nociceptin* (2001) (35)
Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence (2017) (35)
Neural and environmental factors impacting maternal behavior differences in high- versus low-novelty-seeking rats (2010) (35)
Colocalization of estrogen β-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei (2003) (35)
Pattern of c-fos mRNA induction in rat brain by acute morphine (1998) (35)
A bacterially expressed mineralocorticoid receptor is associated in vitro with the 90-kilodalton heat shock protein and shows typical hormone- and DNA-binding characteristics. (1993) (35)
β1 Adrenergic Receptors in the Bed Nucleus of Stria Terminalis Mediate Differential Responses to Opiate Withdrawal (2007) (35)
Pre‐ and Posttranslational Regulation of β‐Endorphin Biosynthesis in the CNS: Effects of Chronic Naltrexone Treatment (1993) (34)
Gene expression profiling of neurochemically defined regions of the human brain by in situ hybridization-guided laser capture microdissection (2009) (34)
Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis. (1998) (34)
Monoaminergic mechanisms of stimulation-produced analgesia Brain Res., 94 (1975) 279–296 (1976) (34)
Characterization of proopiomelanocortin mRNA detected by in situ hybridization (1986) (34)
[Comparison in the rat between analgesia induced by stimulation of periacqueducal gray matter and morphine analgesia]. (1972) (34)
Postdexamethasone plasma cortisol and β-endorphin levels in depression: Relationship to severity of illness (1987) (34)
Does chronic nociceptive stimulation alter the development of morphine tolerance? (1995) (33)
S100A8/A9 Drives Neuroinflammatory Priming and Protects against Anxiety-like Behavior after Sepsis (2018) (33)
Pulse-chase studies of the POMC/beta-endorphin system in the pituitary of acutely and chronically stressed rats. (1982) (33)
Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex (2014) (33)
Neuroanatomical and Neurochemical Substrates of Drug-Seeking Behavior: Overview and Future Directions (1989) (33)
Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding (2018) (33)
Proenkephalin messenger RNA is expressed both in the rat anterior and posterior pituitary. (1990) (33)
Anatomical relationship between opioid peptides and receptors in rhesus monkey brain (1984) (33)
Evidence for Transcriptional Factor Dysregulation in the Dorsal Raphe Nucleus of Patients with Major Depressive Disorder (2012) (33)
Sertoli cells are the primary site of prodynorphin gene expression in rat testis: regulation of mRNA and secreted peptide levels by cyclic adenosine 3' ,5'-monophosphate analogs in cultured cells. (1990) (32)
Evidence against changes in corticotroph CRF receptors in depressed patients (1995) (32)
Pharmacological and anatomical evidence of selective mu, delta, and kappa opioid receptor binding in rat brain. (1986) (32)
SNPs on Chips: The Hidden Genetic Code in Expression Arrays (2007) (32)
Neonatal FGF2 alters cocaine self-administration in the adult rat (2009) (32)
Serotonin 5-HT 1 A , 5-HT 1 B , and 5-HT 2 A Receptor mRNA Expression in Subjects with Major Depression , Bipolar Disorder , and Schizophrenia (2004) (31)
Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety (2015) (31)
Previous experience affects subsequent anxiety-like responses in rats bred for novelty seeking. (2007) (31)
Neonatal fibroblast growth factor treatment enhances cocaine sensitization (2012) (31)
Naloxone blocks amphetamine-induced rearing: Potential interaction between catecholamines and endorphins (1978) (31)
Effect of Cocaine on Fas-Associated Protein with Death Domain in the Rat Brain: Individual Differences in a Model of Differential Vulnerability to Drug Abuse (2009) (30)
Normal pituitary response to metyrapone in the morning in depressed patients: Implications for circadian regulation of corticotropin-releasing hormone secretion (1997) (30)
Atypical prodynorphin gene expression in corticosteroid-producing cells of the rat adrenal gland. (1991) (30)
Mutagenesis of residues adjacent to transmembrane prolines alters D1 dopamine receptor binding and signal transduction. (1996) (30)
Correlation of estrogen beta-receptor messenger RNA with endogenous levels of plasma estradiol and progesterone in the female rat hypothalamus, the bed nucleus of stria terminalis and the medial amygdala. (2002) (30)
Anatomical and biochemical studies of the opioid peptides and related substances in the brain (1980) (29)
Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist Science, 191 (1976) 961–962 (1976) (29)
Characterization of basal nitric oxide production in living cells. (2001) (29)
β-Endorphin processing and cellular origins in rat spinal cord (1992) (28)
Pattern of c-fos mRNA induction in rat brain by acute morphine. (1998) (28)
Plasma measures of B-endorphin-like immunoreactivity in depressives and other psychiatric subjects. (1982) (28)
Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists. (1999) (28)
Decreased locomotor activity in mice expressing tTA under control of the CaMKIIα promoter (2008) (27)
Paradoxical effect of corticosteroids on pituitary ACTH/β-endorphin release in stressed animals (1988) (27)
Cloning and expression of the A2a adenosine receptor from guinea pig brain (1994) (27)
Expression patterns of corticotropin‐releasing factor, arginine vasopressin, histidine decarboxylase, melanin‐concentrating hormone, and orexin genes in the human hypothalamus (2010) (27)
Effects of Low Dose Ovine Corticotropin-Releasing Hormone in Humans: Endocrine Relationships and β: Endorphin/β-Lipotropin Responses* (1988) (27)
Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms (2012) (27)
Neuroendocrine systems I: Overview, thyroid and adrenal axes (1999) (26)
Prodynorphin Biosynthesis and Posttranslational Processing (1993) (26)
Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin. (1982) (26)
Short-Term Adrenalectomy Increases Glucocorticoid and Mineralocorticoid Receptor mRNA in Selective Areas of the Developing Hippocampus (1993) (26)
Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior. (2013) (26)
Behavioral pharmacology of the endorphins. (1982) (26)
Synthesis and characterization of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-labeled fluorescent ligands for the mu opioid receptor. (1997) (26)
Effects of chronic opiate and opioid antagonist treatment on striatal opioid peptides (1995) (26)
Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population (2011) (25)
Localization of neurons containing pro-opiomelanocortin-related peptides in the hypothalamus and midbrain of the lizard, Anolis carolinensis evidence for region-specific processing of β-endorphin (1984) (25)
Neurotransmitters and pain control. (1987) (25)
Female CREBαδ− deficient mice show earlier age-related cognitive deficits than males (2007) (25)
β‐Endorphin/ACTH immunocytochemistry in the CNS of the lizard Anolis carolinensis: Evidence for a major mesencephalic cell group (1984) (25)
Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype (2019) (25)
Strategies for studying opioid peptide regulation at the gene, message and protein levels (1984) (25)
Sample matching by inferred agonal stress in gene expression analyses of the brain (2007) (24)
Pattern of forebrain activation in high novelty-seeking rats following aggressive encounter (2011) (24)
Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat (2008) (24)
Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats (2013) (23)
Changes in releasability of ACTH and Beta-endorphin with chronic stress (1985) (23)
Alpha, beta, and gamma mineralocorticoid receptor messenger ribonucleic acid splice variants: differential expression and rapid regulation in the developing hippocampus. (1998) (23)
Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation (2009) (23)
Development of pituitary pro-opiomelanocortin gene and peptide expression: characterization and effect of repeated intermittent maternal isolation. (1992) (23)
The CCK-system mediates adaptation to novelty-induced stress in the rat: A pharmacological evidence (2007) (23)
Beta-Endorphin and Biosynthetically Related Peptides in the Central Nervous System (1983) (23)
A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains. (1995) (22)
Differential responses to morphine-induced analgesia in the tail-flick test (2008) (22)
Species-specific processing of prodynorphin in the posterior pituitary of mammals. (1987) (22)
CREBαδ– deficient mice show inhibition and low activity in novel environments without changes in stress reactivity (2004) (22)
Risk-assessment and Coping Strategies Segregate with Divergent Intrinsic Aerobic Capacity in Rats (2011) (22)
Genome-wide association study identifies 30 loci associated with bipolar disorder (2019) (22)
In Vitro release of hypothalamic β-endorphin βE by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: Evidence for release of opioid active and inactive βE forms (1990) (22)
Selective Alterations of Opiate Receptor Subtypes in Mono sodium Glutamate‐Treated Rats (1983) (21)
Cloning and characterization of multiple opioid receptors. (1996) (21)
Distribution of Opioids in Brain and Peripheral Tissues (1991) (21)
Plasma beta-endorphin-like immunoreactivity, self reported pain perception and anxiety levels in women during pregnancy and labor. (1982) (21)
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats (2017) (21)
Neuroanatomical and functional studies of peptide precursor-processing enzymes. (1991) (20)
Degradation of [3H]β-endorphin in rat plasma is increased with chronic stress (1989) (20)
A Chimeric Analysis of the Opioid Receptor Domains Critical for the Binding Selectivity of μ Opioid Ligands (1996) (20)
proopiomelanocortin biosynthesis, processing, and secretion, functional implications (1993) (20)
Corticosteroid receptors: a dynamic interplay between protein folding and homeostatic control. Possible implications in psychiatric disorders. (2001) (20)
Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary. (1983) (20)
Effects of chronic cocaine exposure on corticotropin-releasing hormone binding protein in the central nucleus of the amygdala and bed nucleus of the stria terminalis (2004) (20)
The fibroblast growth factor family and mood disorders. (2008) (19)
Cocaine Withdrawal Causes Delayed Dysregulation of Stress Genes in the Hippocampus (2012) (19)
The in Vivo Neurochemical Profile of Selectively Bred High-Responder and Low-Responder Rats Reveals Baseline, Cocaine-Evoked, and Novelty-Evoked Differences in Monoaminergic Systems. (2017) (19)
Protective effects of chronic mild stress during adolescence in the low-novelty responder rat (2016) (19)
Application of microarray technology in primate behavioral neuroscience research. (2006) (18)
Revealing a latent variable: individual differences in affective response to repeated injections. (2015) (18)
Selectively Bred Rats Provide a Unique Model of Vulnerability to PTSD-Like Behavior and Respond Differentially to FGF2 Augmentation Early in Life (2017) (18)
Changes in prodynorphin peptide content following treatment with morphine or amphetamine: possible role in mechanisms of action of drug of abuse. (1989) (17)
Cloning and characterization of a pharmacologically distinct A1 adenosine receptor from guinea pig brain. (1994) (17)
Selective down-regulation of hippocampal glucocorticoid receptors during opiate withdrawal. (2003) (16)
Naloxone administration in chronic hallucinating schizophrenic patients (1979) (16)
Differential cellular regulation of pro-opiomelanocortin by interleukin-1-beta and corticotropin-releasing hormone. (1995) (16)
A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study (1977) (16)
Glucocorticoids and resilience (2019) (16)
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder (2021) (16)
Switching Agonist/Antagonist Properties of Opiate Alkaloids at the δ Opioid Receptor Using Mutations Based on the Structure of the Orphanin FQ Receptor* (2000) (16)
Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety (2019) (16)
The presence of two alpha-MSH positive cell groups in rat hypothalamus. (1979) (15)
Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders (2016) (15)
Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders (2019) (15)
The CCK-system underpins novelty-seeking behavior in the rat: Gene expression and pharmacological analyses (2008) (15)
Cloning of kappa opioid receptors: functional significance and future directions. (1994) (15)
Effects of contextual or olfactory cues previously paired with morphine withdrawal on behavior and pain sensitivity in the rat (2001) (15)
Fibroblast Growth Factor-2: An Endogenous Antidepressant and Anxiolytic Molecule? (2012) (15)
The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems. (1990) (15)
Binding of [3H]dynorphin A to apparent kappa opioid receptors in deep layers of guinea pig cerebral cortex. (1984) (15)
Pharmacological regulation of striatal prodynorphin peptides. (1990) (14)
Fibroblast growth factor 2 regulates activity and gene expression of human post‐mitotic excitatory neurons (2018) (14)
Acute systemic administration of morphine selectively increases mu opioid receptor binding in the rat brain (1984) (14)
Immunohistochemical and biochemical studies of the enkephalins, β-endorphin, and related peptides (1979) (14)
Multiple opioid receptor subtypes in the pituitary-adrenal axis: a cross-species study. (1986) (14)
Differential effects of haloperidol on the rat pituitary: decreased biosynthesis, processing and release of anterior lobe pro-opiomelanocortin. (1990) (14)
Endogenous Opioids at the Intersection of Opioid Addiction, Pain, and Depression: The Search for a Precision Medicine Approach. (2020) (14)
Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats (2012) (14)
Opioid peptides and related substances: immunocytochemistry. (1981) (13)
a-MSH in rat brain: occurrence within and outside of fl-endorphin neurons (1980) (13)
Determinants of ligand selectivity at the kappa-receptor based on the structure of the orphanin FQ receptor. (2002) (13)
Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a stress-induced spatial discrimination deficit (2010) (13)
Prodynorphin gene expression in the rat intermediate pituitary lobe: gender differences and postpartum regulation. (1993) (13)
On the multiplicity of active substances in single neurons: β-endorphin and α-melanocyte stimulating hormone as a model system (1980) (13)
Cognitive Control as a 5-HT1A-Based Domain That Is Disrupted in Major Depressive Disorder (2019) (13)
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat (1985) (13)
Interleukin-1 beta-mediated regulation of mu-opioid receptor mRNA in primary astrocyte-enriched cultures. (1996) (13)
Kinetics of Radiolabeled Adrenocorticotropin Hormone in Infant and Weanling Rats (1997) (12)
Connective Tissue Growth Factor Is a Novel Prodepressant (2018) (12)
Differential impact of a complex environment on positive affect in an animal model of individual differences in emotionality (2013) (12)
Role of steric interactions in the delta opioid receptor selectivity of [D-Pen2, D-Pen5]enkephalin. (2009) (12)
Science and the future of psychiatry. (2000) (12)
Altered Ratios of Beta‐Endorphin:Beta‐Lipotropin Released from Anterior Lobe Corticotropes with Increased Secretory Drive. (1993) (12)
Beta-lipotropin-beta-endorphin response to low-dose ovine corticotropin releasing factor in endogenous depression. Preliminary studies. (1990) (11)
Clinical studies on the role of endorphins in schizophrenia. (1981) (11)
Pituitary regulation in endogenous depression. (1986) (11)
Investigating opioid peptides in schizophrenia and depression. (1986) (11)
Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations (2018) (11)
Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress (2021) (11)
Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups (2016) (11)
Cognitive performance is highly sensitive to prior experience in mice with a learning and memory deficit: failure leads to more failure. (2005) (11)
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey (1985) (11)
Effects of Chronic Morphine Treatment on β‐Endorphin‐Related Peptides in the Caudal Medulla and Spinal Cord (1993) (11)
Evaluation of Sensitivity, Performance and Reproducibility of Microarray Technology in Neuronal Tissue1 (2003) (10)
Dopamine regulation of swim stress induction of the pituitary intermediate lobe proopiomelanocortin system. (1993) (10)
Binding and GTPγS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors (2003) (10)
Opioid and non-opioid behavioral actions of dynorphin A and the dynorphin analogue DAKLI. (1990) (10)
Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction (2020) (10)
Blockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat (2020) (10)
Anatomy of an endogenous antagonist (1999) (10)
Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model (2020) (10)
Characterization of the forms of beta-endorphin and alpha-MSH in the caudal medulla of the rat and guinea pig. (1986) (9)
Heterogeneity in the beta-endorphin immunoreactivity response to electroconvulsive therapy. (1991) (9)
Discovering the Genetics of Complex Disorders Through Integration of Genomic Mapping and Transcriptional Profiling (2005) (9)
Utilizing a unique animal model to better understand human temperament (2017) (9)
[D-Ala2,(F5)Phe4]-dynorphin1–13-NH2 (DAFPHEDYN): A potent analog of dynorphin 1–13 (1987) (9)
Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression. (2003) (9)
alpha-MSH in rat brain: occurrence within and outside of beta-endorphin neurons. (1980) (9)
Coding SNPs included in exon arrays for the study of psychiatric disorders (2008) (9)
Regulation of hippocampal α1d adrenergic receptor mRNA by corticosterone in adrenalectomized rats (2008) (9)
Effects of early-life FGF2 on ultrasonic vocalizations (USVs) and the mu-opioid receptor in male Sprague-Dawley rats selectively-bred for differences in their response to novelty (2019) (9)
Genomic modules and intramodular network concordance in susceptible and resilient male mice across models of stress (2021) (9)
Mapping the receptor domains critical for the binding selectivity of delta-opioid receptor ligands. (1996) (9)
Anatomical and Functional Studies of ACTH and Lipotropin in the Central Nervous System (1981) (9)
Female CREBalphadelta- deficient mice show earlier age-related cognitive deficits than males. (2007) (8)
DOES MK-801 INHIBIT THE DEVELOPMENT OF MORPHINE TOLERANCE IN THE RAT AT SPINAL SITES? (1992) (8)
Opioid agonists and antagonists in schizophrenia. (1980) (8)
Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype. (2014) (8)
Recent studies on dynorphin and enkephalin precursor fragments in central nervous system. (1982) (8)
POMC in rhesus anterior pituitary and plasma: Evidence of N-acetylated β-endorphin and α-MSH (1983) (8)
The Functional Relevance of the Heteromeric Structure of Corticosteroid Receptors a (1994) (8)
Corticosterone induces discrete epigenetic signatures in the dorsal and ventral hippocampus that depend upon sex and genotype: focus on methylated Nr3c1 gene (2022) (7)
Some of the α-NH2-acetylated β-endoprhin-like material in rat and monkey pituitary and brain is acetylated α- and β-endorphin (1983) (7)
MULTIPLE FORMS OF BETA-ENDORPHIN (βE) IN PITUITARY AND BRAIN: EFFECT OF STRESS (1981) (7)
Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNA (1993) (7)
Introduction to Social Neuroscience: Gene, Environment, Brain, Body (2011) (7)
Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brain (1988) (7)
Adaptation to single housing is dynamic: Changes in hormone levels, gene expression, signaling in the brain, and anxiety-like behavior in adult male C57Bl/6J mice (2019) (7)
Identification of potential blood biomarkers associated with suicide in major depressive disorder (2022) (7)
Pheromone-induced anorexia in male Syrian hamsters. (2003) (7)
The signal peptide of pro-opiomelancortin: validation of a specific radioimmunoassay. (1982) (7)
Increase in delta, but not mu, receptors in MSG-treated rats. (1982) (7)
Altered Ratios of Beta‐Endorphin : Beta‐Lipotropin Released from Anterior Lobe Corticotropes with Increased Secretory Drive. I. Effects of Diminished Glucocorticoid Secretion (1993) (7)
Beta-endorphin processing and cellular origins in rat spinal cord. (1992) (7)
OPIOID PEPTIDES AND VASOPRESSIN The Application of In Situ Hybridization to Studies of the Hypothalamus and Pituitary (1986) (7)
Law & Neuroscience: The Case of Solitary Confinement (2018) (6)
Neural cell adhesion molecule peptide mimetics modulate emotionality: pharmacokinetic and behavioral studies in rats and non-human primates (2018) (6)
Inference of Cell Type Composition from Human Brain Transcriptomic Datasets Illuminates the Effects of Age, Manner of Death, Dissection, and Psychiatric Diagnosis (2016) (6)
ENKEPHALINASE: PRELIMINARY CHARACTERIZATION AND COMPARISON WITH ANGIOTENSIN CONVERTING ENZYME (1980) (6)
Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors (2019) (6)
Tissue-specific and substrate-specific endoproteolytic cleavage of monkey pro-opiomelanocortin in heterologous endocrine cells: processing at Lys-Lys dibasic pairs. (1993) (6)
beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone. (1986) (6)
Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans (1987) (6)
Stress amplifies sex differences in primate prefrontal profiles of gene expression (2017) (6)
Effect of imipramine administration and swim stress on the hypothalamic pituitary adrenal axis (1994) (6)
Neuromodulatory functions of the brain pro-opiocortin system. (1980) (5)
Molecular aspects of the stress axis and serotonergic function in depression (1993) (5)
5 – Anatomy of β-Endorphin-Containing Structures in Pituitary and Brain (1981) (5)
Changes in Proopiomelanocortin Primary Transcript Levels in the Anterior Pituitary Accompany Increased Adrenocorticotropin Secretion During the Diurnal Surge (1992) (5)
Identifying gene and protein names from biological texts (2003) (5)
CHARACTERIZATION OF 3H-β-ENDORPHIN BINDING IN RAT BRAIN (1980) (5)
Antibodies to enkephalins: coupling of antigens and a specific methionine-enkephalin radioimmunoassay. (1977) (5)
Nucleus accumbens cocaine-amphetamine regulated transcript mediates food intake during novelty conflict (2016) (5)
Opioid Peptides and Vasopressin (1986) (5)
beta-Endorphin and schizophrenia. (1980) (4)
LOCALIZATION OF MU AND KAPPA OPIOID RECEPTORS IN RAT COLON BY ANTIBODIES TO THE CLONED OPIOID RECEPTORS. (1995) (4)
Regulation of mRNA in Peptidergic Systems: Quantitative and In Situ Studies (1988) (4)
Postmortem Neurochemical Investigation of Suicide (1988) (4)
Fluorescent imaging of mitochondrial nitric oxide in living cells. (2002) (4)
Bridge peptide is a cleavage product of pro-dynorphin processing in the rat anterior pituitary. (1986) (4)
Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. (2016) (4)
“Endorphins, Dopamine, and Schizophrenia”: Two Discussions (1979) (4)
Effects of electrical stimulation in the periaqueductal gray on POMC peptides and mRNA in the rat brain. (1990) (4)
APPARENT EVIDENCE OF RECEPTOR SUBTYPES: RECEPTOR BINDING STUDIES WITH THE CLONED RAT AND HUMAN KAPPA RECEPTORS (1995) (4)
Opioid receptor mRNA expression in primary cultures of glial cells derived from different rat brain regions (1994) (4)
Identification of prodynorphin and proenkephalin mRNA expressing cells in the neurointermediate lobe of the rat pituitary gland. (1990) (4)
A Possible Explanation for the Effect of Acupuncture on Pain (1975) (4)
Fibroblast Growth Factor 2 Sits at the Interface of Stress and Anxiety (2016) (4)
Characterization of multiple forms of beta-E in pituitary and brain: effect of stress. (1982) (3)
Alterations in brain β-endorphin immunoreactivity following acute and chronic stress (1981) (3)
Opioid peptides: endogenous analgesics? (1984) (3)
In vitro release of hypothalamic beta-endorphin (beta E) by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: evidence for release of opioid active and inactive beta E forms. (1990) (3)
General discussion II (2008) (3)
Effects of low dose ovine corticotropin-releasing hormone in humans: endocrine relationships and beta-endorphin/beta-lipotropin responses. (1988) (3)
Building Bridges through Science (2017) (3)
Interaction between cholecystokinin and the fibroblast growth factor system in the ventral tegmental area of selectively bred high- and low-responder rats (2013) (3)
Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine (2022) (3)
Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder (2022) (3)
Molecular basis for dynorphin A selectivity: A chimeric study (1994) (3)
Central Stress Neurocircuits (2007) (3)
Regulation of beta-endorphin biosynthesis in the brain: different effects of morphine pelleting and repeated stress. (1991) (3)
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. (2016) (3)
Prospects for the evaluation of endorphins as psychotropic agents. (1979) (3)
Circulating adrenal hormones are not necessary for the development of sensitization to the psychomotor activating effects of amphetamine (Brain Res. 673 (1995) 13–24) (BRES 10891) (1995) (3)
Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model (2021) (3)
Effect of hypophysectomy on dynorphin mRNA and peptide content in the rat adrenal gland. (1990) (3)
γ-melanotropin and β-endorphin after dexamethasone (1989) (3)
[Monoaminergic mechanisms involved in analgesia caused by stimulation of the brain stem in rats]. (1972) (2)
Effects of morphine treatment on endogenous opioid biosynthesis. (1988) (2)
Contrast medium cause the apparent increase in beta-endorphin levels in human CSF following brain stimulation. (1985) (2)
ANATOMICAL AND BIOCHEMICAL STUDIES OF DYNORPHIN (1981) (2)
Optimization and evaluation of fluorescence in situ hybridization chain reaction in cleared fresh-frozen brain tissues (2021) (2)
Screening potential allele-frequency disequilibrium in Data from Affymetrix gene expression Arrays (2005) (2)
SAT-358 Corticosterone Treatment during Sepsis Results in a Primary Adrenal Defect in Male Survivors (2019) (2)
DISTRIBUTION OF PROENKEPHALIN mRNA IN THE RAT DISTAL COLON: AN IN SITU HYBRIDIZATION STUDY. (1995) (2)
Cloning of potential candidates for guinea pig opioid receptors (1994) (2)
Pharmacological and Anatomical Evidence of Selective , D , 6 , and 3 c Opioid Receptor Binding in Rat Brain (2002) (2)
Some of the alpha-NH2-acetylated beta-endorphin-like material in rat and monkey pituitary and brain is acetylated alpha- and beta-endorphin. (1983) (2)
Tritiated ethylketocyclazocine binding in rat brain: differential distribution of binding sites across brain regions. (1982) (2)
Pain reduction: a comparison of stimulation produced and narcotic analgesia (1973) (2)
Effect of Selective Lesions of Nucleus Accumbens µ-Opioid Receptor-Expressing Cells on Heroin Self-Administration in Male and Female Rats: A Study with Novel Oprm1-Cre Knock-in Rats (2022) (2)
Constitutive activity of the d -opioid receptor expressed in C6 glioma cells: identiﬁcation of non-peptide d -inverse agonists (1999) (2)
alters the stress response in mice Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and (2007) (1)
Corticotrophin- releasing factor, beta-endorphin and somatostatin depressed patients treated with electroconvulsive therapy. Neuropeptide concentrations in the cerebrospinal fluid of (2011) (1)
Molecular studies of multiple opioid receptors: Cloning, anatomical distribution, pharmacological profile (1994) (1)
Characterization of the Forms of fl-Endorphin and a-MSH in the Caudal Medulla of the Rat and Guinea Pig (2002) (1)
shRNA Silencing of Endogenous FGF2 in Rat Hippocampus Increases Anxiety Behavior (2011) (1)
Enkephalin-like material in normal human CSF: measurement and levels H. Akil, S.J. Watson, S. Sullivan and J.D. Barchas, Life Sci., 23 (1978) 121–126 (1979) (1)
Opportunities for Computational Psychiatry (2016) (1)
Gamma-melanotropin and beta-endorphin after dexamethasone. (1989) (1)
Chronic stress in adolescence differentially affects cocaine vulnerability in adulthood in a selectively bred rat model of individual differences: role of accumbal dopamine signaling (2020) (1)
The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality TRUJILLO, K. A. AND H. AKIL. PHARMACOL BIOCHEM BEHAV 38(3) 673–675, 1991. (1991) (1)
Cloning and characterization of a pharmacologically distinct A 1 adenosine receptor from guinea pig brain (2002) (1)
P26 INDIVIDUAL DIFFERENCES IN PAVLOVIAN CONDITIONED APPROACH BEHAVIOR (2004) (1)
Optimization and evaluation of fluorescence in situ hybridization chain reaction in cleared fresh-frozen brain tissues (2021) (1)
Bruce McEwen, 1938–2020 (2020) (1)
Gamma-3-MSH and beta-endorphin in monkey pituitary. (1986) (1)
Transcriptional Profiling of the Hippocampus in an F2 Cross of a Genetic Rat Model of Internalizing vs. Externalizing Behavior and Addiction Liability (2022) (1)
Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits (2022) (1)
Studies related to the metabolic processing of endogenous opioids (1981) (1)
Complexity and Heterogeneity in Psychiatric Disorders: Opportunities for Computational Psychiatry (2016) (1)
THE EFFECT OF ACUTE ADMINISTRATION OF MORPHINE AND OPIATE ANTAGONISTS ON THE INDOLE CONTENT OF THE RAT PINEAL GLAND (1980) (1)
Mitochondria Genetics of Schizophrenia and Bipolar Disorder (2021) (1)
MULTIPLE OPIATE BINDING SITES IN RAT BRAIN: DIFFERENTIAL DISPLACEMENT OF 3H-NALOXONE BINDING BY DIFFERENT OPIATE LIGANDS (1980) (1)
Genomic Modules and Intramodular Network Convergency of Susceptibility and Resilience in Multimodeled Stress in Male Mice (2021) (1)
Studies using antibodies generated against peptide sequences from opioid binding protein and antibodies against rhodopsin (1990) (1)
Adolescent cocaine differentially impacts psychomotor sensitization and epigenetic profiles in adult male rats with divergent affective phenotypes (2022) (1)
P.2.b.009 The melanin-concentrating hormone system and emotional-like behaviour (2011) (1)
POMC in rhesus anterior pituitary and plasma: evidence of N-acetylated beta-endorphin and alpha-MSH. (1983) (1)
Degradation of [3H]beta-endorphin in rat plasma is increased with chronic stress. (1989) (1)
Optimization and quantitative evaluation of fluorescence in situ hybridization chain reaction in clarified fresh-frozen brain tissues (2019) (1)
Point Mutations in the 90‐kDa Heat Shock Protein Binding Region of the Glucocorticoid Receptor Affect the Functional Characteristics of the Receptor a (1995) (1)
Functional aspects of multitransmitter neurons. Studies of interactions among pro-opiomelanocortin products. (1987) (1)
DISCRETE REGIONAL DISTRIBUTION FOR ENKEPHALINASE AND AMINOPEPTIDASE IN MICRODISSECTED RAT BRAIN (1981) (1)
Emerging Roles of Glial Cell Types in the Regulation of Temperament and Mood (2022) (0)
Neurotransmission-Related Gene Expression in the Frontal Pole (Brodmann Area 10) is Altered in Subjects with Bipolar Disorder and Schizophrenia (2022) (0)
Title Page / Contents / Acknowledgments / Preface (1987) (0)
in Endogenous Depression Effect of Dexamethasone (2017) (0)
Elizabeth Young (2009) (0)
23. A Genetic and Developmental Model of Temperament in the Rat: Role of Neuroplasticity and Relevance to Human Mood Disorders (2017) (0)
Opioid Efficacy in a C 6 Glioma Cell Line Stably Expressing the Delta Opioid Receptor 1 (1997) (0)
S-22-4 Mineralocorticoid receptor mRNA variants in the developing hippocampus: Distribution and regulation (1996) (0)
Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder (2021) (0)
Special issue dedicated to Dr. Eric J. Simon (1996) (0)
Anomalous binding of DPDPE as a result of batch variability. (1986) (0)
[gamma]-Msh potentiates acth analgesia (1981) (0)
mtDNA copy number, mtDNA total somatic deletions, Complex I activity, synapse number and synaptic mitochondria number are altered in schizophrenia and bipolar disorder (2022) (0)
Complexity and heterogeneity in psychiatry: opportunities for computational approaches (2016) (0)
Dorsal lateral prefrontal cortex and mediodorsal thalamus in schizophrenic brains show concordant and discordant alterations in gene expression (2003) (0)
γ-Msh potentiates acth analgesia (1981) (0)
Recent Advances in Pain Management (1976) (0)
Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans (2018) (0)
Chronic, nonhabituating physical and social stress during adolescence alter hippocampal morphology and gene expression in rats (2000) (0)
Chapter III Neuroanatomical studies of the opioid receptor-like-1 receptor and its endogenous neuropeptide orphanin FQ (nociceptin) (2002) (0)
Acknowledgement of Reviewers 2014 (2015) (0)
Stress, Genetics and Mood: Impact of COVID-19 on a College Freshman Sample (2022) (0)
Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats (2011) (0)
Public and Policy Challenges to Neuropsychopharmacology (1998) (0)
Candesartan reverses depression‐like behavior and negative cardiovascular changes in a rodent model of depression: comparison to the selective serotonin reuptake inhibitor fluoxetine (2011) (0)
psychosis: a convergent functional genomics approach Identifying a series of candidate genes for mania and (2005) (0)
Experiment 3 : Are there Pre-Existing and / or Diet-Induced Differences in Hedonic Responses to Sucrose in Rats Susceptible to Obesity ? Taste reactivity (2015) (0)
Early acquisition of threat conditioning in a selectively-bred anxiety-like rat phenotype: regulation by maternal presence and FGF2 (2021) (0)
Letters to the Editor (1985) (0)
In Person: The Pursuit of Happiness (2009) (0)
Gene transfer and expression in mammalian cell lines: A method to study regulation of neuropeptide processing (1989) (0)
Room 302, 10/17/2000 9: 00 AM - 10: 30 AM (PD) Acute Treatment with Opioids and Stimulants Alter RGS4 mRNA Levels in Rat Brain A-127 (2000) (0)
A Meta-Analysis of Hippocampal Transcriptional Profiling Studies in a Selectively-Bred Rat Model Provides Converging Evidence with Genetic Sequencing to Implicate Specific Candidate Genes and Pathways in the Liability for Internalizing and Externalizing Psychiatric Disorders (2019) (0)
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats (2017) (0)
On the Role of Endorphins in Pain Modulation (1982) (0)
Functional Aspects of Multitransmitter Neurons (1987) (0)
Handbook of Psychopharmacology (1983) (0)
The Brain in Isolation (2019) (0)
215. Altered hormonal response to a social stressor in major depression (2000) (0)
Erratum: Mitochondrial involvement in psychiatric disorders (Annals of Medicine (2008) 40 (281-295)) (2011) (0)
$266 Y-msh Potentiates Acth Alteratict~s in Stress-indu~ Anal~sia: Effects on Stress- 1 (0)
Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3′ Breakpoints (2022) (0)
DOES THE INTENSITY OF NOXIOUS STIMULATION INFLUENCE C-FOS ACTIVATION PATTERNS IN RAT BRAIN? (1998) (0)
Heterogeneity in the beta-endorphin response to ECT (1989) (0)
Altered Ratios of Beta-Endorp h i n: Beta-Li potropi n Released from Anterior Lobe Corticotropes with Increased Secretory Drive. II. Repeated Stress (1993) (0)
In Memory of Elizabeth Young (2009) (0)
P23 GENETIC FACTORS,BUTNOT THEREINFORCING PROPERTIESOFETHANOL, INFLUENCECONDITIONED REINSTATEMENTOFALCOHOL-SEEKING INRATS (2004) (0)
Age-related changes in the POMC stress axis in the rat (1990) (0)
Normal response to AM metyrapone administration in depressed patients (1994) (0)
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder (2018) (0)
Stress amplifies sex differences in primate prefrontal profiles of gene expression (2017) (0)
GAMMA+lRLANOTROPIN RESPONSE TO OVINE CORTICOTROPIN RELEASING FACTOR IN NORHAL RDtUNS (1987) (0)
Research Report Cloning and characterization of a pharmacologically distinct A 1 adenosine receptor from guinea pig brain (1994) (0)
Photoperiodic effects on hypothalamic β-endorphin and POMC mRNA (1994) (0)
High emotional reactivity is associated with activation of a molecularly distinct hippocampal-amygdala circuit modulated by the glucocorticoid receptor (2022) (0)
Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia (2023) (0)
97-5 Molecular and circuit targets for drug development in the brain's stress systems (1997) (0)
Determination of the relative positions between TMH V and VI of the μ opioid receptor using site-directed mutagenesis (2002) (0)
Room D, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Chronic Administration of Opioids and Psychostimulants Alter RGS4 mRNA Levels in Rat Brain A-779 (2000) (0)
The effects of haloperidol on μ, δ and κ opioid receptor mRNA expression in the striatum (1994) (0)
A BINDS SELECTIVELY TO GUINEA PIG BRAIN (2002) (0)
THE EFFECTS OF HALOPERIDOL ON p, ~ A N D K OPIOID RECEPTOR m R N A EXPRESSION IN THE STRIATUM (2002) (0)
Candesartan reverses depression‐like behavior in a rodent model of depression (2010) (0)
Analyzing gene expression in depression. (2009) (0)
Trait Locus Brain HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. (2016) (0)
Expression and processing of POMC in a neuronal cell line (1990) (0)
PHARMACOLOGY OF THE ENDORPHINS (1982) (0)
191. Gene expression arrays: their power and their limits (2000) (0)
442 – MULTIPLE OPIOID SYSTEMS IN BRAIN: ENKEPHALINS AND β-ENDORPHIN/3-LPH/ACTH (1978) (0)
FGF-2 related methods for the diagnosis and treatment of depression (2006) (0)
β-Endorphin Responsiveness in Depression-Reply (1993) (0)
Overexpression of mineralocorticoid receptor in forebrain: Effects on HPA function and behavior (2006) (0)
Relationship between stress-induced analgesia and the POMC/β-endorphin system in the pituitary: Changes in β-endor-phin biosynthesis in acutely and chronically stressed rats (1983) (0)
Forebrain Glucocorticoid Receptor Overexpression Alters Behavioral Encoding of Hippocampal CA1 Pyramidal Cells in Mice (2022) (0)
Hormonal effects on extra- and intraneural mechanism: an integrative approach (1993) (0)
Patterns of Neural Activation During an Initial Social Stress Encounter are Predictive of Future Susceptibility or Resilience: A FosTRAP2 Study (2023) (0)
In vivo neurochemical profile of selectively bred high-responder and low-responder rats reveals baseline, cocaine- and novelty-evoked differences in monoaminergic systems (2018) (0)
Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F2 Cross of Selectively-Bred Rats (2023) (0)
56-3 How does the brain regulate the stress response: Anatomical and biochemical perspectives (1997) (0)
Knowledge-Based Analysis of Genome-Wide SNP Scanning Data (2006) (0)
Long-term prospective study of lumbosacral discectomy P.J. Lewis, B.K.A. Weir, R.W. Broad and M.G. Grace, J. Neurosurg., 67 (1987) 49–53 (1988) (0)
Anatomy of CN$ opMd receptors (1988) (0)
The effects of haloperidol on [mu], [delta] and [kappa] opioid receptor mRNA expression in the striatum (1994) (0)
Post-mortem molecular profiling of three psychiatric disorders (2017) (0)
Why a special issue on complex genetics (1999) (0)
Cocaine during adolescence differentially impacts psychomotor sensitization and epigenetic profiles in adult male rats with divergent affective phenotypes (2022) (0)
β-Endorphin and ACTH function: Pre- and post-synaptic phenomena (1979) (0)

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