Ihor R. Lemischka | Academic Influence

Ihor R. Lemischka's AcademicInfluence.com Rankings

Ihor R. Lemischka

Biology

#3077

World Rank

#4760

Historical Rank

#1294

USA Rank

Molecular Biology

#1044

World Rank

#1068

Historical Rank

#200

USA Rank

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Biology

Ihor R. Lemischka's Degrees

Bachelors Biology University of California, San Diego

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Why Is Ihor R. Lemischka Influential?

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According to Wikipedia, Ihor R. Lemischka was an American stem cell biologist and stem cell research advocate and was both the Lillian and Henry M. Stratton Professor of Gene and Cell Medicine and Director of the Black Family Stem Cell Institute at Mount Sinai Medical Center in New York City.

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Ihor R. Lemischka's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Stem Cells and Their Niches (2006) (1590)
A Stem Cell Molecular Signature (2002) (1574)
Dissecting self-renewal in stem cells with RNA interference (2006) (1051)
Developmental potential and dynamic behavior of hematopoietic stem cells (1986) (826)
Patient-specific induced pluripotent stem cell derived models of LEOPARD syndrome (2010) (704)
Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. (1995) (653)
A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations (1991) (619)
Three different fibronectin mRNAs arise by alternative splicing within the coding region (1983) (611)
The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells (2006) (605)
Clonal and systemic analysis of long-term hematopoiesis in the mouse. (1990) (588)
Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network (2011) (554)
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. (1991) (540)
Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse (1984) (456)
The genetic program of hematopoietic stem cells. (2000) (426)
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. (2012) (410)
In vitro maintenance of highly purified, transplantable hematopoietic stem cells. (1997) (384)
Systems biology of stem cell fate and cellular reprogramming (2009) (366)
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells (2011) (323)
shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. (2007) (319)
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (2013) (317)
Cellular and developmental properties of fetal hematopoietic stem cells (1990) (308)
Systems-level dynamic analyses of fate change in murine embryonic stem cells (2009) (291)
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells (2011) (236)
Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA. (1981) (227)
Functional heterogeneity of the hematopoietic microenvironment: rare stromal elements maintain long-term repopulating stem cells. (1996) (226)
A molecular profile of a hematopoietic stem cell niche (2002) (224)
Induction of a hemogenic program in mouse fibroblasts. (2013) (211)
Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells. (1999) (209)
Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells (1993) (208)
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2017) (199)
The sequences of an expressed rat α-tubulin gene and a pseudogene with an inserted repetitive element (1982) (176)
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity (2012) (175)
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. (2009) (175)
The molecular characterization of the fetal stem cell marker AA4. (1999) (171)
Modeling Familial Cancer with Induced Pluripotent Stem Cells (2015) (167)
Statistical Mechanics of Pluripotency (2013) (162)
Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term. (1997) (155)
Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system. (2001) (139)
Smarcc1/Baf155 Couples Self‐Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells (2009) (137)
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. (2012) (134)
Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming (2012) (130)
Prdm16 is a physiologic regulator of hematopoietic stem cells. (2011) (121)
A Genomewide Functional Network for the Laboratory Mouse (2008) (121)
Expression of CD27 on murine hematopoietic stem and progenitor cells. (2000) (111)
Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation. (1995) (109)
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. (2006) (106)
Stem cells: Interactive niches (2003) (103)
Microenvironmental regulation of hematopoietic stem cells (1997) (99)
Construction and Validation of a Regulatory Network for Pluripotency and Self-Renewal of Mouse Embryonic Stem Cells (2014) (95)
Single Transcription Factor Reprogramming of Hair Follicle Dermal Papilla Cells to Induced Pluripotent Stem Cells (2011) (94)
ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells (2013) (89)
The myeloid-lymphoid initiating cell (ML-IC) assay assesses the fate of multipotent human progenitors in vitro. (1999) (86)
The murine stromal cell line AFT024 acts specifically on human CD34+CD38- progenitors to maintain primitive function and immunophenotype in vitro. (1998) (80)
Epigenetic roles of MLL oncoproteins are dependent on NF-κB. (2013) (78)
A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. (2002) (74)
Diversification of stem cell molecular repertoire by alternative splicing. (2005) (73)
Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming. (2015) (72)
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. (2009) (72)
A few thoughts about the plasticity of stem cells. (2002) (71)
Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia. (2015) (66)
Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells. (2011) (65)
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal (2013) (60)
Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression (1985) (59)
Genomic editing tools to model human diseases with isogenic pluripotent stem cells. (2014) (55)
Stem cells and reprogramming: breaking the epigenetic barrier? (2011) (54)
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. (2014) (54)
The power of stem cells reconsidered? (1999) (51)
Making a Hematopoietic Stem Cell. (2016) (47)
Stem cell dogmas in the genomics era. (2001) (46)
Response to Comments on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (2003) (46)
What we have learned from retroviral marking of hematopoietic stem cells. (1992) (43)
Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm (2015) (42)
Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal (2015) (42)
“Tie-ing” down the Hematopoietic Niche (2004) (39)
Complementation of Myc-dependent cell proliferation by cDNA expression library screening (2000) (37)
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency (2012) (36)
Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells. (2016) (36)
The haematopoietic stem cell and its clonal progeny: mechanisms regulating the hierarchy of primitive haematopoietic cells. (1992) (36)
GATE: software for the analysis and visualization of high-dimensional time series expression data (2009) (35)
Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders (2011) (34)
A dual molecular analogue tuner for dissecting protein function in mammalian cells (2016) (34)
The return of clonal marking sheds new light on human hematopoietic stem cells (2001) (33)
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism (2018) (33)
Clonal, in vivo behavior of the totipotent hematopoietic stem cell. (1991) (31)
Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification. (2016) (31)
Toward a complete in silico, multi‐layered embryonic stem cell regulatory network (2010) (29)
Toward stem cell systems biology: from molecules to networks and landscapes. (2008) (29)
Delivery of short hairpin RNAs—triggers of gene silencing—into mouse embryonic stem cells (2006) (28)
Rethinking somatic stem cell plasticity (2002) (27)
SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells (2010) (26)
Modeling Cancer with Pluripotent Stem Cells. (2016) (26)
Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming (2018) (26)
Stem Cell Biology: A View toward the Future (2005) (24)
Alternative Splicing Increases Complexity of Stem Cell Transcriptome (2006) (23)
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells (2010) (22)
Searching for Stem Cell Regulatory Molecules Some General Thoughts and Possible Approaches (1999) (21)
Patient-specific Induced Pluripotent Stem Cells as a Platform for Disease Modeling, Drug Discovery and Precision Personalized Medicine (2012) (21)
Reprogramming cell fates: insights from combinatorial approaches (2012) (21)
Patterning pluripotency in embryonic stem cells (2013) (19)
A differential network analysis approach for lineage specifier prediction in stem cell subpopulations (2015) (18)
Hooking up with Oct4. (2010) (18)
Cloning and characterization of fetal liver phosphatase 1, a nuclear protein tyrosine phosphatase isolated from hematopoietic stem cells. (1996) (18)
Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation (2011) (17)
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2 (2010) (17)
The time is right: proteome biology of stem cells. (2008) (17)
Feedback control of pluripotency in embryonic stem cells: Signaling, transcription and epigenetics. (2018) (16)
Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming (2016) (15)
Expression of Podocalyxin Separates the Hematopoietic and Vascular Potentials of Mouse Embryonic Stem Cell‐Derived Mesoderm (2014) (13)
Retroviral lineage studies: some principals and applications. (1993) (13)
Exploration of self-renewal and pluripotency in ES cells using RNAi. (2010) (12)
Proteome biology of stem cells. (2007) (12)
Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells (2019) (9)
Proteome Biology of Stem Cells (2008) (8)
Prdm 16 is a physiologic regulator of hematopoietic stem cells (2011) (8)
Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen (2015) (8)
An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions (2021) (6)
Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate (2017) (5)
Quantitative Approaches to Model Pluripotency and Differentiation in Stem Cells (2013) (5)
SETD 6 mono-methylates H 2 AZ on lysine 7 ( H 2 AZK 7 me 1 ) and is required for the maintenance of embryonic stem cell self-renewal (2013) (4)
Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments (2018) (4)
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture (2019) (4)
LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes (2021) (4)
“There will be blood” from fibroblasts (2013) (4)
NetExplore: a web server for modeling small network motifs (2015) (3)
Purification and properties of fetal hematopoietic stem cells (1993) (3)
Emerging Modeling Concepts and Solutions in Stem Cell Research. (2016) (3)
Cells for repair: breakout session summary. (2002) (3)
Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN 11-Associated Juvenile Myelomonocytic Leukemia Graphical (2015) (3)
Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program. (2016) (1)
Development of the Sixth ISSCR Annual Meeting Program (2008) (1)
Engineering a 1:2 bio-multiplexer for controlled stem cell differentiation (2005) (1)
Correction: Corrigendum: MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (2013) (1)
Biological and Quantitative Models for Stem Cell Self-Renewal and Differentiation (2013) (1)
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2022) (1)
Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation (2022) (1)
Optimized induction of human hemogenesis in adult fibroblasts (2017) (1)
Tex 10 Coordinates Epigen etic Control of Super-Enhancer Activity in Pluripotency and Reprogramming Graphical Abstract Highlights (2015) (0)
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME LXXIII (2009) (0)
Abstract 5129: Model osteosarcoma by Li-Fraumeni syndrome patient-specific induced pluripotent stem cells (2015) (0)
Abstract 17784: The Genesips Project: an NHLBI-Sponsored induced Pluripotent Stem Cell (iPSC) Resource for the Study of Cardiovascular Diseases (2014) (0)
MicroRNAs in Development, Stem Cell Differentiation, and Regenerative Medicine (2012) (0)
Omics Era in Stem Cell Research: Data Integration of Multi-regulatory Layers (2012) (0)
3 – (Post) Genomic Stem Cell (2004) (0)
Hematopoiesis/early commitment (WS-011) Chairpersons: Toshio Kitamura, Harinder Singh (2010) (0)
Elucidation of the mechanisms of hematopoietic reprogramming (2017) (0)
EMBRYONIC STEM CELLS / INDUCED PLURIPOTENT STEM CELLS Smarcc 1 / Baf 155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells (2009) (0)
Pursuing pluripotency (LL2-4)Chairperson: Toshio Kitamura (2010) (0)
Abstract PR05: Familial cancer patient specific iPSCs based study of a potential oncogenic factor, sFRP2, in osteosarcoma (2018) (0)
Analyzing myeloid differentiation on multiple fronts (2001) (0)
system tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact Umbilical cord blood cells capable of engrafting in primary, secondary, and (2013) (0)
Zero footprint induction of human hemogenesis to study pathologic developmental hematopoiesis in fanconi anemia (2016) (0)
Stem cell 'SLAMalot' (2005) (0)
Rezeptor Protein Tyrosin-Kinase (1992) (0)
Molecular Study of Interactions between Hematopoietic Stem Cells and Stromal Cells (2002) (0)
Hematopoietic stem cells, explicitly (2006) (0)
Mechanisms underlying human hemogenic reprogramming (2016) (0)
Hematopoietic stem cells, explicitly Microtubules, leukemia, and cough syrup (2006) (0)
A Novel MBT-Containing Protein, Hemp, Plays Essential Roles In Skeletal Formation and Hematopoietic Stem Cell Function. (2010) (0)
Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen (2015) (0)

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