John Paul Blass
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Austrian physician and biochemist
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Why Is John Paul Blass Influential?
(Suggest an Edit or Addition)According to Wikipedia, John P. Blass, physician, biochemist and neurochemist, was born on February 21, 1937 in Vienna, Austria, and deceased March 12, 2023 in New York City. Both his parents were physicians; his father, Gustaf Blass, was a prominent Viennese radiologist and his mother, Jolan Wirth Blass, a student of Sigmund Freud, was a psychoanalyst originally from Budapest. The family then moved to Stamford, Connecticut. Both parents practiced psychiatry, Gustaf in a private sanitarium in Stamford and Jolan as a child psychiatrist in New York City and Connecticut. He is survived by his wife, son and two granddaughters.
John Paul Blass's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A 30-Week Randomized Controlled Trial of High-Dose Tacrine in Patients With Alzheimer's Disease (1994) (905)
- Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' (1998) (548)
- Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications (2005) (529)
- Instruments for the functional assessment of older patients. (1990) (439)
- Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. (1988) (397)
- Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome. (1977) (362)
- Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain (1983) (350)
- Abnormalities of mitochondrial enzymes in Alzheimer disease (1998) (339)
- Depression in patients referred to a dementia clinic. A three-year prospective study. (1985) (333)
- IMPAIRED SYNTHESIS OF ACETYLCHOLINE IN BRAIN ACCOMPANYING MILD HYPOXIA AND HYPOGLYCEMIA (1976) (301)
- A defect in pyruvate decarboxylase in a child with an intermittent movement disorder. (1970) (246)
- Brain dysfunction in mild to moderate hypoxia. (1981) (245)
- Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces. (1975) (239)
- Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. (2010) (205)
- Pathology of Alzheimer's disease. (1991) (202)
- Association Between Acute Care and Critical Illness Hospitalization and Cognitive Function in Older Adults (2010) (198)
- Mitochondrial function in brain tissue in primary degenerative dementia (1987) (187)
- The α-ketoglutarate dehydrogenase complex in neurodegeneration (2000) (182)
- Inherent Abnormalities in Energy Metabolism in Alzheimer Disease: Interaction with Cerebrovascular Compromise (2000) (176)
- Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype (2000) (171)
- Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease (1998) (168)
- The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease. (1991) (161)
- Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia? (2001) (160)
- Altered calcium uptake in cultured skin fibroblasts from patients with Alzheimer's disease. (1985) (158)
- An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain (1985) (156)
- Regional distribution of astrocytes with intense immunoreactivity for glutamate dehydrogenase in rat brain: implications for neuron-glia interactions in glutamate transmission (1987) (152)
- The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration. (2005) (145)
- The Mitochondrial Spiral: An Adequate Cause of Dementia in the Alzheimer's Syndrome (2000) (141)
- Zn2+ Inhibits α-Ketoglutarate-stimulated Mitochondrial Respiration and the Isolated α-Ketoglutarate Dehydrogenase Complex* (2000) (137)
- Induction of Alzheimer antigens by an uncoupler of oxidative phosphorylation. (1990) (136)
- Absence of Vascular Dementia in an Autopsy Series from a Dementia Clinic (1998) (131)
- The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha (2009) (129)
- Survival in Alzheimer's disease and vascular dementias (1985) (128)
- An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates. (1981) (127)
- Dementia and motor neuron disease: Morphometric, biochemical, and Golgi studies (1984) (123)
- Mediterranean Diet and Mild Cognitive Impairment (2009) (123)
- Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases. (1998) (119)
- Altered metabolic properties of cultured skin fibroblasts in Alzheimer's disease (1987) (117)
- Autism and lactic acidosis (1985) (114)
- Inhibition of Brain Glycolysis by Aluminum (1984) (113)
- Ketonic diet in the management of pyruvate dehydrogenase deficiency. (1976) (112)
- Clinical studies of a patient with pyruvate decarboxylase deficiency. (1971) (105)
- A Parallel Group Placebo Controlled Study of Prazosin for Trauma Nightmares and Sleep Disturbance in Combat Veterans with Post-Traumatic Stress Disorder (2008) (104)
- ALTERATIONS IN ACETYLCHOLINE SYNTHESIS AND CYCLIC NUCLEOTIDES IN MILD CEREBRAL HYPOXIA (1978) (103)
- Pathophysiology of the Alzheimer's syndrome (1993) (103)
- Alzheimer's disease. A metabolic systems degeneration? (1984) (101)
- Thiamine-dependent processes and treatment strategies in neurodegeneration. (2007) (100)
- Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. (1997) (100)
- Intensive nutritional supplements can improve outcomes in stroke rehabilitation (2008) (99)
- Clinically Approved Heterocyclics Act on a Mitochondrial Target and Reduce Stroke-induced Pathology (2004) (99)
- Factors associated with duration of survival in Alzheimer's disease (1985) (98)
- Polyglutamine Domains Are Substrates of Tissue Transglutaminase: Does Transglutaminase Play a Role in Expanded CAG/Poly‐Q Neurodegenerative Diseases? (1997) (97)
- Abnormality of the α‐ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease (1994) (94)
- Low activities of the pyruvate and oxoglutarate dehydrogenase complexes in five patients with Friedreich's ataxia. (1976) (93)
- The role of the metabolic lesion in Alzheimer's disease. (2002) (92)
- Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson’s disease (2003) (91)
- The α‐Ketoglutarate Dehydrogenase Complex (1999) (90)
- BIOCHEMICAL ABNORMALITIES IN LEIGH'S DISEASE (1976) (87)
- Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal (1984) (86)
- Glial glutamate dehydrogenase: Ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase (1987) (84)
- Impairment of behavior and acetylcholine metabolism in thiamine deficiency. (1981) (83)
- The alpha-ketoglutarate dehydrogenase complex in neurodegeneration. (2000) (81)
- Sensitivity to Carbohydrate in a Patient with Familial Intermittent Lactic Acidosis and Pyruvate Dehydrogenase Deficiency (1976) (80)
- THE ROLE OF THE CHOLINERGIC SYSTEM IN THIAMIN DEFICIENCY * (1982) (79)
- Duration of antihypertensive drug use and risk of dementia: A prospective cohort study (2009) (79)
- Pathogenesis of Inclusion Bodies in (CAG)n/Qn‐Expansion Diseases with Special Reference to the Role of Tissue Transglutaminase and to Selective Vulnerability (1999) (78)
- INHIBITION OF ACETYLCHOLINE SYNTHESIS AND OF CARBOHYDRATE UTILIZATION BY MAPLE‐SYRUP‐URINE DISEASE METABOLITES (1976) (77)
- Unrecognized Cognitive Impairment in Cardiac Rehabilitation Patients (1988) (77)
- Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. (1976) (77)
- An inherited defect affecting the tricarboxylic acid cycle in a patient with congenital lactic acidosis. (1972) (76)
- N ε ‐(γ‐l‐Glutamyl)‐l‐lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease (2001) (76)
- Energy metabolism in disorders of the nervous system. (1988) (74)
- Determinants of Quality of Life in Stroke Survivors and Their Informal Caregivers (2007) (74)
- Overdiagnosis of Dementia (1981) (74)
- Zn2+ inhibits alpha-ketoglutarate-stimulated mitochondrial respiration and the isolated alpha-ketoglutarate dehydrogenase complex. (2000) (73)
- Thiamine and Alzheimer's disease. A pilot study. (1988) (73)
- Delirium accelerates cognitive decline in Alzheimer disease (2009) (71)
- Cross linking of polyglutamine domains catalyzed by tissue transglutaminase is greatly favored with pathological-length repeats: does transglutaminase activity play a role in (CAG) n /Q n -expansion diseases? (2002) (70)
- Cerebrometabolic Aspects of Delirium in Relationship to Dementia (1999) (69)
- Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity (2009) (69)
- Rapid diagnosis of pyruvate and ketoglutarate dehydrogenase deficiencies in platelet-enriched preparations from blood. (1977) (67)
- Altered oxidation and signal transduction systems in fibroblasts from Alzheimer patients. (1996) (67)
- 4-Aminopyridine in the treatment of alzheimer's disease (1988) (66)
- Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients (2011) (65)
- A trial of thiamine in Alzheimer's disease. (1991) (65)
- Increased levels of γ‐glutamylamines in Huntington disease CSF (2008) (63)
- THE REGULATION OF PYRUVATE DEHYDROGENASE IN BRAIN IN VIVO (1976) (63)
- Studies on the Pyruvate Dehydrogenase Complex in Brain with the Arylamine Acetyltransferase‐Coupled Assay (1982) (63)
- Alzheimer’s disease and Alzheimer’s dementia: distinct but overlapping entities (2002) (62)
- Pentoxifylline in Cerebrovascular Dementia (1992) (62)
- Diminished mitogen-induced calcium uptake by lymphocytes from alzheimer patients (1987) (62)
- Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria. (2005) (61)
- Does cognitive impairment predict poor self-care in patients with heart failure? (2010) (60)
- Expression of Classical Mitochondrial Respiratory Responses in Homogenates of Rat Forebrain (1986) (60)
- Altered glucose metabolism in fibroblasts from patients with Alzheimer's disease. (1985) (60)
- A possible mechanism for selective cerebellar damage in partial pyruvate dehydrogenase deficiency (1976) (59)
- Balance Score and a History of Falls in Hospital Predict Recurrent Falls in the 6 Months Following Stroke Rehabilitation (2008) (58)
- Use of Cultured Fibroblasts in Elucidating the Pathophysiology and Diagnosis of Alzheimer's Disease a (1994) (58)
- Physostigmine in familial ataxias (1977) (53)
- Neuronal Subclass-Selective Loss of Pyruvate Dehydrogenase Immunoreactivity Following Canine Cardiac Arrest and Resuscitation (2000) (53)
- High levels of amyloid-beta protein from S182 (Glu246) familial Alzheimer's cells. (1995) (53)
- The Cellular Basis of Delirium and Its Relevance to Age-Related Disorders Including Alzheimer's Disease (1991) (53)
- Localization of the oxidative defect in phytanic acid degradation in patients with Refsum's disease. (1969) (52)
- A relation between (NAD+)/(NADH) potentials and glucose utilization in rat brain slices. (1976) (52)
- Abnormal activation of private dehydrogenase in Leigh disease fibroblasts (1982) (52)
- Thiamin in the elderly--relation to alcoholism and to neurological degenerative disease. (1982) (50)
- Cerebrometabolic abnormalities in Alzheimer's disease (2003) (49)
- Mitochondrial enzymes in schizophrenia (2007) (48)
- Kinetic properties of the partially purified pyruvate dehydrogenase complex of ox brain. (1973) (46)
- Phosphofructokinase activity in the brain in Alzheimer's disease (1987) (46)
- Intermittent ataxia with pyruvate-decarboxylase deficiency. (1971) (46)
- Metabolic alterations common to neural and non‐neural cells in alzheimer's disease (1993) (45)
- Selective loss of KGDHC-enriched neurons in alzheimer temporal cortex (2001) (45)
- Mitochondrial Aconitase is a Transglutaminase 2 Substrate: Transglutamination is a Probable Mechanism Contributing to High-Molecular-Weight Aggregates of Aconitase and Loss of Aconitase Activity in Huntington Disease Brain (2005) (45)
- Studies of transketolase abnormality in Alzheimer's disease. (1988) (44)
- MEASUREMENT OF ACETYLCHOLINE TURNOVER WITH GLUCOSE USED AS PRECURSOR: EVIDENCE FOR COMPARTMENTATION OF GLUCOSE METABOLISM IN BRAIN (1978) (44)
- Pyruvate oxidation in neuromuscular diseases (1974) (44)
- Leisure activities and the risk of amnestic mild cognitive impairment in the elderly (2008) (44)
- Red Blood Cell Abnormalities in Alzheimer Disease (1985) (43)
- Carbohydrates and Acetylcholine Synthesis: Implications for Cognitive Disorders (1979) (42)
- Disorders of pyruvate metabolism (1979) (42)
- Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population (1999) (42)
- The string test: An early behavioral change in thiamine deficiency (1981) (41)
- The α-ketoglutarate-dehydrogenase complex (2007) (41)
- Regulation of sterol synthesis in human skin fibroblast cultures (1970) (40)
- Follow Up of Patients Referred to a Dementia Service (1984) (39)
- Preventing cognitive decline. (1992) (39)
- A translation of Otto Binswanger's article, 'The delineation of the generalized progressive paralyses'. 1894. (1991) (39)
- Glucose/mitochondria in neurological conditions. (2002) (38)
- A comparison of the regulation of pyruvate dehydrogenase in mitochondria from rat brain and liver. (1975) (38)
- Normal levels of acetyl coenzyme A and of acetylcholine in the brains of thiamin‐deficient rats 1 (1975) (37)
- Midlife and Late-Life Obesity and the Risk of Dementia: Cardiovascular Health Study (2009) (37)
- Genetic factors in Wernicke-Korsakoff syndrome. (1979) (36)
- Nonneural markers in Alzheimer disease. (1992) (36)
- Consequences of mild, graded hypoxia. (1979) (36)
- Pyruvate Dehydrogenase Phosphate (PDHb) Phosphatase in Brain: Activity, Properties, and Subcellular Localization (1983) (34)
- Correlation of the clinical severity of alzheimer’s disease with an aberration in mitochondrial DNA (mtDNA) (2001) (33)
- Losing A Million Minds Losing a Million Minds: Confronting the Tragedy of Alzheimer's Disease and Other Dementias (1987) (33)
- Relationship between Cognitive Status and Behavioral Symptoms in Alzheimer's Disease and Mixed Dementia (1993) (31)
- Underdiagnosis of Cognitive Impairment in a Rehabilitation Setting (1984) (31)
- Glyceraldehyde 3-Phosphate Dehydrogenase Abnormality in Metabolically Stressed Huntington Disease Fibroblasts (1998) (31)
- Computerized Data Base for Evaluation and Follow‐up of Demented Outpatients (1984) (30)
- Properties and Regional Distribution of Pyruvate Dehydrogenase Kinase in Rat Brain (1984) (30)
- A sensitive fluorometric assay for tissue transglutaminase. (2001) (29)
- Expression in cultured human neuroblastoma cells of epitopes associated with affected neurons in Alzheimer's disease. (1990) (29)
- Lysine-Rich Histone (H1) Is a Lysyl Substrate of Tissue Transglutaminase: Possible Involvement of Transglutaminase in the Formation of Nuclear Aggregates in (CAG)n/Qn Expansion Diseases (2000) (29)
- Effects of Postdecapitative Ischemia on Mitochondrial Respiration in Brain Tissue Homogenates (1986) (29)
- Inherent abnormalities in oxidative metabolism in Alzheimer's disease: interaction with vascular abnormalities. (1997) (29)
- Circulating Vitamins in Alzheimer's Dementia as Compared with Other Dementias (1984) (28)
- 3,4-Diaminopyridine as a treatment for amyotrophic lateral sclerosis (1995) (28)
- N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease. (2001) (28)
- Neurotoxic effects of copper: Inhibition of glycolysis and glycolytic enzymes (1984) (28)
- Rates of decrease of cerebral blood flow in progressive dermentias (1984) (27)
- Cerebral blood flow decrements in chronic head injury syndrome (1985) (27)
- The role of transglutaminases in neurodegenerative diseases: overview (2002) (26)
- Letter: Biochemical abnormalities in Leigh's disease. (1976) (25)
- Stages of Alzheimer's Disease (1984) (25)
- Carnitine, carnitine acetyltransferase, and glutathione in Alzheimer brain (1995) (25)
- Kinetic Studies of Mouse Brain Transketolase (1982) (25)
- The simple monosubstituted guanidines of mammalian brain. (1960) (25)
- Mitochondrial dysfunction and spinocerebellar degenerations. (1986) (25)
- Cholinergic therapy of abnormal open-field behavior in thiamin-deficient rats. (1982) (24)
- A double-blind placebo-controlled study of 3,4-diaminopyridine in amytrophic lateral sclerosis patients on a rehabilitation unit (1996) (24)
- Expression of 'Alzheimer antigens' in cultured skin fibroblasts. (1991) (24)
- Red-cell/plasma choline ratio in dementia. (1982) (24)
- A DLST genotype associated with reduced risk for Alzheimer’s disease (1999) (24)
- Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older (2008) (23)
- Human red blood cell choline uptake with age and Alzheimer's disease (1986) (23)
- Spectrophotometric measurement of pyruvate dehydrogenase complex activity in cultured human fibroblasts. (1981) (23)
- Randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and tolerability of metrifonate in patients with probable Alzheimer disease. The Metrifonate Study Group. (2000) (23)
- Aerobic Conditioning: An Effective Therapy in McArdle's Disease (2008) (23)
- The subcellular localization of glutamate dehydrogenase (GDH): is GDH a marker for mitochondria in brain? (1986) (23)
- Normal replicative lifespan of Alzheimer skin fibroblasts (1988) (22)
- Proportional inhibition of acetylcholine synthesis accompanying impairment of 3-hydroxybutyrate oxidation in rat brain slices. (1979) (22)
- Studies of the pathophysiology of pyruvate dehydrogenase deficiency. (1978) (22)
- Metabolism and Alzheimer’s Disease (2004) (22)
- Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease. (1994) (21)
- Cholinergic Dysfunction: A Common Denominator in Metabolic Encephalopathies (1981) (21)
- What is aging? What is its role in Alzheimer's disease? What can we do about it? (2005) (21)
- Dexamethasone suppression test in depression with reversible dementia (1985) (21)
- Immunohistochemical colocalization of amyloid precursor protein with cerebrovascular amyloid of Alzheimer's disease. (1991) (21)
- Volume changes in Alzheimer's disease and mild cognitive impairment: cognitive associations (2010) (20)
- Regionally selective alterations in enzymatic activities and metabolic fluxes during thiamin deficiency (2004) (20)
- Localization of the gene (OGDH) coding for the E1k component of the alpha-ketoglutarate dehydrogenase complex to chromosome 7p13-p11.2. (1994) (20)
- Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population (2004) (20)
- Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of humanα-ketoglutarate dehydrogenase complex (1994) (19)
- Use of Cultured Skin Fibroblasts in Studies of Alzheimer’s Disease (1989) (19)
- Risk Factors in Alzheimer’s Disease (1986) (19)
- Pyruvate dehydrogenase deficiencies (1980) (18)
- Inhibition by acetaldehyde of the pyruvate dehydrogenase complex from ox brain and ox kidney. (1973) (18)
- Mental Status Tests in Geriatrics (1985) (18)
- Evidence for a primary defect of lipoamide dehydrogenase in Friedreich's ataxia. (1978) (18)
- Regional decline of cerebral blood flow with age in cognitively intact subjects (1984) (18)
- The Oxidation of β-Hydroxybutyric Acid by Small Quantities of Type-pure Red and White Skeletal Muscle (1971) (18)
- Delirium: Phenomenology and Diagnosis—A Neurobiologic View (1991) (18)
- Metabolism and Neurotransmission (1983) (17)
- Iatrogenic nutritional deficiencies. (1982) (17)
- Lack of clinical benefit from naloxone in a dementia day hospital (1984) (17)
- Culture from human leptomeninges of cells containing neurofilament protein and neuron-specific enolase (1994) (17)
- Biological Markers For Alzheimer’s Disease (1986) (17)
- FATTY ACID COMPOSITION OF CEREBROSIDES IN MICROSOMES AND MYELIN OF MOUSE BRAIN (1970) (16)
- Deficiency of pyruvate dehydrogenase complex (PDHC) in Leigh's disease fibroblasts (1989) (16)
- Correlations of disability and biologic alterations in Alzheimer brain and test of significance by a therapeutic trial in humans. (2006) (16)
- A reproducible procedure for primary culture and subsequent maintenance of multiple lines of human skin fibroblasts (1998) (16)
- Action of physostigmine on inherited ataxias. (1978) (15)
- A placebo‐controlled trial shows no effect of vasopressin on recovery from closed head injury (1982) (15)
- Quality of Life After Stroke: The North East Melbourne Stroke Incidence Study (NEMESIS) (2006) (15)
- Cholinergic Systems and Disorders of Carbohydrate Catabolism (1978) (15)
- Oxidative/Energy Metabolism in Neurodegenerative Disorders (2000) (14)
- Cultured cells as a screen for novel treatments of Alzheimer's disease. (1989) (14)
- Thiamin and Alzheimer's disease. (1992) (14)
- Expression in Escherichia coli and purification of hexahistidine-tagged human tissue transglutaminase. (2002) (14)
- Toward an effective treatment of Alzheimer's disease. (1983) (14)
- NEWER CONCEPTS OF PSYCHIATRIC DIAGNOSIS AND BIOCHEMICAL RESEARCH ON MENTAL ILLNESS (1977) (14)
- Does 8-Foot Walk Time Predict Cognitive Decline in Older Mexican Americans? (2008) (14)
- Normal glutamate metabolism in Alzheimer's disease fibroblasts deficient in alpha-ketoglutarate dehydrogenase complex activity. (1996) (14)
- Cholinesterase inhibitors and opiate antagonists in patients with Alzheimer's disease. (1983) (13)
- Presence of typical neuronal markers in serially cultured cells from adult human brain (1992) (13)
- Testing for Linkage and Association Across the Dihydrolipoyl Dehydrogenase Gene Region with Alzheimer’s Disease in Three Sample Populations (2007) (13)
- An enzymatic and immunochemical analysis of transketolase in fibroblasts from Wernicke-Korsakoff syndrome (1993) (13)
- Lower activity of Krebs cycle enzymes than of electron transport in human brain: Disease implications (2000) (12)
- Satisfaction with End-of-Life Care for Nursing Home Residents with Advanced Dementia (2008) (12)
- Decline in cognitive and functional skills increases mortality risk in nondemented elderly (2008) (12)
- Presence of neuronal proteins in serially cultured cells from autopsy human brain (1994) (12)
- A New Approach to Treating Alzheimer's Disease (2008) (12)
- Protection by tris(hydroxymethyl)-aminomethane against behavioral and neurochemical effects of hypoxia. (1979) (12)
- "Silent" strokes and dementia. (2003) (12)
- The alpha-ketoglutarate dehydrogenase complex. (1999) (11)
- Systemic manifestations of Alzheimer’s disease (1988) (10)
- Measurement of citrate synthase activity in human fibroblasts. (1971) (10)
- Age‐Associated Memory Impairment and Alzheimer's Disease (1996) (10)
- Life-Long Morbidity Among Danes With Poliomyelitis (2006) (10)
- Conference Summary: Mitochondria, Neurodegenerative Diseases, and Selective Neuronal Vulnerability (1999) (10)
- Human leptomeningeal-derived cells express GFAP and HLADR when grafted into rat spinal cord (1996) (9)
- Differential effects of monovalent, divalent and trivalent metal ions on rat brain hexokinase. (1985) (9)
- Immunologic treatment of Alzheimer's disease. (1999) (9)
- Deficiency of glutamate dehydrogenase in postmortem brain samples from parkinsonian putamen (1990) (9)
- Self-reported Depression and Use of Antidepressants After Stroke: A National SurveyEriksson M, for the Riks-Stroke Collaboration (Umeå Univ, Sweden; et al) Stroke 35:936–941, 2004§ (2006) (9)
- Pseudogene of dihydrolipoyl succinyltransferase (E2k) found by PCR amplification and direct sequencing of rodent-human cell hybrid DNAs (1994) (9)
- Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly-Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions? (1998) (9)
- Physical Activity, Cognitive Function, and Mortality in a US National Cohort (2010) (9)
- Presence of low amounts of “neuronal” antigens in cultured human skin fibroblasts (1992) (8)
- The gene for the alpha polypeptide of pyruvate dehydrogenase is X-linked in humans. (1990) (8)
- Haplotype Analysis and a Novel Allele-Sharing Method Refines a Chromosome 4p Locus Linked to Bipolar Affective Disorder (2008) (8)
- Heredopathia atactica polyneuritiformis (Refsum's Disease): a second trial of dietary therapy in two patients. (1971) (8)
- Substantial Linkage Disequilibrium Across the Dihydrolipoyl Succinyltransferase Gene Region Without Alzheimer's Disease Association (2004) (8)
- The inhibition of prions through blocking prion conversion by permanently charged branched polyamines of low cytotoxicity (2010) (8)
- Pyruvate dehydrogenase phosphate (PDHb) phosphatase activity in fibroblasts from Leigh's disease (1984) (7)
- STUDIES OF “NEURONAL” AND “ALZHEIMER” ANTIGENS IN SKIN CELLS (1988) (7)
- Predictors of In-Hospital Mortality in Patients With Acute Ischemic Stroke Treated With Thrombolytic Therapy (2006) (7)
- Predicting Recovery of Upper-Body Dressing Ability After Stroke (2008) (7)
- Energy/Glucose Metabolism in Neurodegenerative Diseases (1997) (7)
- A population-based study of depressive symptoms in multiple sclerosis in Stockholm county: association with functioning and sense of coherence (2008) (7)
- Tissue culture and studies of human brain disease (1992) (7)
- Lecithin in hereditary ataxia (1981) (6)
- Implantation of cultured human leptomeningeal cells into rat brain (1997) (6)
- Quality of end-of-life care for dementia patients during acute hospital admission: a retrospective study in Ireland (2010) (6)
- Elevated Red Cell to Plasma Choline Ratios in Alzheimer’s Disease (1986) (6)
- Length of Stay, Discharge Destination, and Functional Improvement: Utility of the Australian National Subacute and Nonacute Patient Casemix Classification (2008) (6)
- Abnormalities in Pyruvate Dehydrogenase and Neurologic Function (1972) (6)
- Nutrition and Brain Function (1999) (6)
- The cultured fibroblast model. (1994) (6)
- Failure of CT Scan to Detect Ischemic Lesions in Patients With Dementia (1993) (6)
- Expression of Neuronal Proteins in Cells from Normal Adult Rat Brain Propagated in Serial Culture (1994) (6)
- α-Hydroxy fatty acids in hereditary ataxic polyneuritis (Refsum's disease) (1969) (6)
- Neurochemical mechanisms in disease (2011) (6)
- Mitochondria, Aging, and Neurological Diseases (1995) (6)
- Thiamine and Alzheimer's Disease (2017) (6)
- High levels of amyloid-β protein from S182 (Glu246) familial Alzheimer's cells (1995) (6)
- Pigeon liver phosphoprotein phosphatase: an effective activator of pyruvate dehydrogenase in tissue homogenates. (1986) (5)
- Oxidative metabolism and acetylcholine synthesis during acetylpyridine treatment (1985) (5)
- Differences in the responses of brain cytosolic and mitochondrial hexokinases to three essential divalent metal ions. (1985) (5)
- Alzheimer's disease: inborn error of metabolism of late onset? (1990) (5)
- Measurement of pyruvate dehydrogenase complex in crude tissue homogenate with an nadh linked spectrophotometric assay (1981) (5)
- Enrichment of cholesterol in microdissected Alzheimer's disease senile plaques as assessed by mass spectrometry (2010) (5)
- Phosphofructokinase activity in fibroblasts from patients with Alzheimer's disease and age- and sex-matched controls (1986) (5)
- Clinical assays of lipoamide dehydrogenase (1981) (5)
- Human A β-amyloid and amyloid precursor protein accumulates in rat brain cells after cultured human leptomeningeal fibroblast implants (1997) (4)
- Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the CSF of patients with Alzheimer's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process (2010) (4)
- Alzheimer's Disease: New Treatment Strategies (1992) (4)
- Oral Physostigmine and Inherited Ataxias (1979) (4)
- Chapter 5 Metabolism of the Aging Brain (1997) (4)
- Randomized clinical stroke trials in 2003 (2004) (4)
- A central cholinergic deficit in rats with dietary thiamin deficiency (1983) (4)
- Diagnosis of Alzheimer's disease and multi-infarct dementia by rCBF compared to clinical classification. (1984) (4)
- New developments in the diagnosis of the dementias (1985) (4)
- Deficit in a Krebs cycle mitochondrial enzyme in brains from patients with Parkinson's disease (2001) (4)
- NIH Diagnostic Criteria for Alzheimer's Disease (1985) (3)
- Chromosomal fragility associated with familial Alzheimer's disease (1994) (3)
- Binswanger's Disease and German Translations-Reply (1992) (3)
- Randomized Clinical Stroke Trials in 2007 (2008) (3)
- Mitochondria, neurodegenerative diseases, and selective neuronal vulnerability. (1999) (3)
- Brain tissue volumes in relation to cognitive function and risk of dementia (2010) (3)
- Circulatory and Degenerative Dementias (1987) (3)
- Mechanisms of enzymatic degradation of amyloid Beta microfibrils generating nanofilaments and nanospheres related to cytotoxicity (2010) (3)
- Pyruvate Dehydrogenase Deficiency in 35 Patients1 (1978) (3)
- Primary degenerative dementia. (1986) (3)
- Disorders of Fatty Acids (1973) (2)
- Hereditary ataxias (1984) (2)
- Mitochondrial enzymes in hereditary ataxias (1988) (2)
- Diagnosis of Alzheimer Disease (2020) (2)
- Clinical Interview Assessment of Financial Capacity in Older Adults with Mild Cognitive Impairment and Alzheimer's Disease (2009) (2)
- The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease (2009) (2)
- Alzheimer's disease. (1985) (2)
- Deficiency of a Specific Diaphorase in Luft Disease Fibroblasts (1983) (2)
- Cerebral Metastases Mimicking Depression in a “Forgetful” Attorney (1984) (2)
- Pragmatic Pointers on Managing the Demented Patient (1986) (2)
- Measurement of metabolic activities in small samples of muscle. (1970) (2)
- Induction of epitopes associated with neurofibrillary tangles in clonal mouse neuroblastoma (S20Y) cells (2004) (2)
- INBORN ERRORS, INBORN PREDISPOSITIONS, AND NORMAL VARIATION: SOME IMPLICATIONS FOR PSYCHIATRIC RESEARCH (1982) (2)
- Potential for a specific neuroradiologic diagnosis of Alzheimer's disease. (2002) (2)
- α-Ketoglutarate Dehydrogenase in Alzheimer’s Disease (1996) (2)
- Cerebral Metabolic Impairments (1996) (2)
- Admission C-Reactive Protein Does Not Predict Functional Outcomes in Patients with Strokes in a Subacute Rehabilitation Unit (2008) (2)
- Respite-retreat for dementia caregivers: A demonstration (1993) (2)
- Nutrition and Functional Neurochemistry (1999) (2)
- The importance of mitochondrial damage in Alzheimer's disease varies according to APOE genotype (2000) (2)
- A Randomized Controlled Trial of Early Supported Discharge and Continued Rehabilitation at Home After Stroke: Five-Year Followup of Patient Outcome (2006) (2)
- ENZYMES OF ENERGY METABOLISM IN DEMENTED BRAIN (1984) (1)
- Regional Cerebral Blood Flow In Dementia: Receiver-Operating-Characteristic Analysis (1985) (1)
- Red Cell/Plasma Choline Ratio as a Peripheral Marker in Alzheimer's Disease (1986) (1)
- Absence of neuronal and glial proteins in human and rat leptomeninges in situ (1996) (1)
- Association Between Lifetime Cigarette Smoking and Lewy Body Accumulation (2010) (1)
- Randomized clinical stroke trials in 2006. (2008) (1)
- Survivors‐only bias in estimating survival in Alzheimer's disease and vascular dementias (1986) (1)
- Trinucleotide-Expansion Diseases (2011) (1)
- O4-05-06 An adjunct treatment for Alzheimer disease (AD) (2004) (1)
- Randomized clinical stroke trials in 2004 (2005) (1)
- White matter in the elderly (1990) (1)
- Mitochondrial Abnormalities in Hereditary Ataxias (1992) (1)
- Impaired acetylcholine synthesis accompanying reduced pyruvate oxidation in rat brain minces (1974) (1)
- Rapid rate of decline in cerebral blood flow in progressive dementias. (1984) (1)
- Contents Vol. 18, 1996 (2004) (1)
- Prevalence and Predictors of Depression at One Year in a Swedish Population-Based Cohort With First-Ever Stroke (2006) (1)
- P4-066 Independent case-control confirmation of association of DLD with AD (2004) (1)
- Pyruvate dehydrogenase deficiency in 35 patients. (1978) (1)
- The Effect of a Task-Oriented Walking Intervention on Improving Balance Self-Efficacy Poststroke: A Randomized, Controlled Trial (2007) (1)
- Clinical classification of regional cerebral blood flow (RCBF) by partitioning. (1984) (1)
- Alpha-hydroxy fatty acids in hereditary ataxic polyneuritis (Refsum's disease). (1969) (1)
- Discussion: Acetylcholine and the caudate. (1975) (1)
- Nutrition and the Treatment of Neurodegenerative Disease (1999) (1)
- INVESTIGATION OF SUSPECT DEMENTIA (1981) (1)
- Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2 (2010) (1)
- Longevity and Aging Research: An Analysis of the Reality (1984) (1)
- The Development of a Rapid Screen for Caregiver BurdenHirschman KB, Shea JA, Xie SX, et al (Univ of Pennsylvania, Philadelphia) J Am Geriatr Soc 52:1724–1729, 2004§ (2006) (1)
- Randomized clinical stroke trials in 2004. (2010) (1)
- Vitamin Bl2 deficiency in dementia disorders. Bjorn Regland. Departments of Psychiatry and Neurochemistry, St Jorgen Hospital, University of Goteborg, Sweden, 1991. No. of pages: 148 (1991) (0)
- DLST allele found as yet only in Alzheimer patients (2000) (0)
- Insight, cognition and quality of life in Alzheimer's disease (2010) (0)
- Nutrition and Brain Development (1999) (0)
- Detection de maladies neurodegeneratives (1998) (0)
- Metabolic Changes Associated With Second-Generation Antipsychotic Use in Alzheimer’s Disease Patients: The CATIE-AD Study (2009) (0)
- Metrifonateof its Use in Alzheimer's Disease (2000) (0)
- Functional Correlates and Prevalence of Mild Parkinsonian Signs in a Community Population of Older PeopleLouis ED, Tang MX, Schupf N (Columbia Univ, New York) Arch Neurol 62:297–302, 2005§ (2006) (0)
- Mechanisms Versus Diagnoses (2011) (0)
- Interrelationships of Energy Metabolism to Oxidative Damage and Neurodegeneration (1998) (0)
- Abnormal mitochondrial constituents coded by the nuclear genome in Alzheimer disease (1996) (0)
- BINSWANGER'S DISEASE AND GERMAN TRANSLATIONS. AUTHORS' REPLY (1992) (0)
- In reply (1999) (0)
- Clinical aspects and noninvasive diagnostic approaches (1986) (0)
- Estimating Prognosis for Nursing Home Residents With Advanced DementiaMitchell SL, Kiely DK, Hamel MB, et al (Harvard Med School, Boston; Beth Israel Deaconess Med Ctr, Boston; Univ of Michigan) JAMA 291:2734–2740, 2004§ (2006) (0)
- Neuronal Control of Food Intake (1999) (0)
- Thiamin and the Wernicke-Korsakoff Syndrome (2017) (0)
- Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease (2008) (0)
- Quality of Life and Burden of Spouses of Alzheimer Disease Patients (2009) (0)
- Genetic approaches to neurobiology (1979) (0)
- Brief Postoperative Delirium in Hip Fracture Patients Affects Functional Outcome at Three MonthsZakriya K, Sieber FE, Christmas C, et al (Johns Hopkins Bayview Med Ctr, Baltimore, Md) Anesth Analg 98:1798–1802, 2004§ (2006) (0)
- Special Report from the Challenging Views of Alzheimer ’ s Disease What is aging ? What is its role in Alzheimer ’ s disease ? What can we do about it ? (2005) (0)
- GENERAL DISCUSSION OF NEUROLOGICAL AND MEDICAL ASPECTS OF THIAMIN (1982) (0)
- Molecular neurogenetics (1981) (0)
- A Clinical Trial of Pentoxifylline in Vascular Dementia (1991) (0)
- Commentary on “Diagnosis of Alzheimer’s disease: Two decades of progress.” Perspectives on “Perspectives” (2005) (0)
- Contents Vol. 22, 2000 (2000) (0)
- Clinical trials in stroke in 2002 (2003) (0)
- Accidents in Patients With Epilepsy: Types, Circumstances, and Complications: A European Cohort Studyvan den Broek M, for the RESt-1 Group (Istituto di Ricerche Farmacologiche “Mario Negri,” Milano, Italy; et al) Epilepsia 45:667–672, 2004§ (2006) (0)
- Comprar Neurochemical mechanisms in disease (advances in neurobiology, vol. 1) | John P. Blass | 9781441971036 | Springer (2011) (0)
- Association Between Visual Attention and Mobility in Older AdultsOwsley C, McGwin G Jr (Univ of Alabama, Birmingham) J Am Geriatr Soc 52:1901–1906, 2004§ (2006) (0)
- APP overexpression prevents neuropathic pain and motoneuron death after peripheral nerve injury in mice (2010) (0)
- Regulated APP processing via a-Secretase Pathway in FAD Fibroblasts (1994) (0)
- Antioxidants in prevention of AD: Dissapointments and possibilities (2005) (0)
- P4-244 Abnormalities in mitochondrial components in Alzheimer brain: mechanistic implications (2004) (0)
- Biological markers in Alzheimer's and Parkinson's disease (1986) (0)
- A cDNA Cloning and the Nucleotide Sequence of Human Transketolase in Normal and Wernicke-Korsakoff Syndrome (1997) (0)
- Cognitive deficits in chronic heart failure (2010) (0)
- Nutrition and Structural Aspects of the Brain (1999) (0)
- Subject Index Vol. 18, 1996 (1996) (0)
- Role of the Interleukin-6–174 G>C Gene Polymorphism in Retinal Artery Occlusion (2006) (0)
- Nutrition and Genetics (1999) (0)
- Clinical Management of the American Patient with Dementia (1986) (0)
- Convergence mechanisms in aging of the brain: A thermodynamic approach (1992) (0)
- Clinical trials of treatments for stroke (2002) (0)
- Cholinesterase inhibitors: More than one function in AD? (2003) (0)
- P4-391 Correlations of neurobiologic abnormalities with clinical disabilities in Alzheimer disease (AD) (2006) (0)
- Presentation of the Academy medal to Irving S. Wright, M.D. (1986) (0)
- Editors List From 1976 To 2009 (2009) (0)
- Preface (1999) (0)
- V. Promising Directions of Research (1981) (0)
- Cyclin towards, or away from, dementia? (2002) (0)
- Subject Index Vol. 22, 2000 (2000) (0)
- Accumulations of phytanic acid in Refsum's disease. (1969) (0)
- Nutrition and Aging of the Nervous System (1999) (0)
- Clinical and Demographic Predictors of Long-term Disability in Patients With Relapsing-Remitting Multiple Sclerosis: A Systematic Review (2008) (0)
- Comprar Handbook of Neurochemistry and Molecular Neurobiology · Neurochemical Mechanisms in Disease | Blass, John | 9780387303574 | Springer (2009) (0)
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