Richard Wurtman
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American neuroscientist
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Richard Wurtman's Degrees
- Bachelors Psychology Columbia University
- Masters Medicine Albert Einstein College of Medicine
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Why Is Richard Wurtman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Richard Wurtman was an American neuroscientist who spent his career doing basic and translational neuroscience research at Massachusetts Institute of Technology. Early life and education Richard Wurtman earned his undergraduate degree at University of Pennsylvania and then went to Harvard Medical School, where he earned his MD in 1960. He did a two year residency at Massachusetts General Hospital, and then joined Julius Axelrod's lab at the National Institutes of Health, which was pioneering studies of neurotransmitters and the ways that drugs affect them.
Richard Wurtman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels (1971) (998)
- A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE. (1963) (940)
- Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. (1992) (915)
- Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids (1972) (816)
- Brain Serotonin Content: Increase Following Ingestion of Carbohydrate Diet (1971) (697)
- Precursor control of neurotransmitter synthesis. (1980) (666)
- Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. (1994) (608)
- A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. (1967) (563)
- Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. (1966) (529)
- Nutrition and the brain. (1990) (520)
- Evidence for a membrane defect in Alzheimer disease brain. (1992) (518)
- Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization (1980) (514)
- Effects of exogenous melatonin on sleep: a meta-analysis. (2005) (473)
- Brain serotonin content: physiological regulation by plasma neutral amino acids. (1997) (465)
- Choline and cholinergic neurons. (1983) (431)
- Melatonin Synthesis in thePineal Gland: Control by Light (1963) (412)
- Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. (1993) (391)
- Brain acetylcholine: control by dietary choline. (1976) (376)
- CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING. (1965) (365)
- Brain Catechol Synthesis: Control by Brain Tyrosine Concentration (1974) (344)
- Brain acetylcholine: increase after systemic choline administration. (1975) (336)
- Adrenaline Synthesis: Control by the Pituitary Gland and Adrenal Glucocorticoids (1965) (312)
- Sleep‐inducing effects of low doses of melatonin ingested in the evening (1995) (308)
- Bioavailability of oral melatonin in humans. (1984) (303)
- The effects of low doses of caffeine on human performance and mood (2004) (301)
- Brain serotonin, carbohydrate-craving, obesity and depression. (1995) (299)
- Melatonin, a Pineal Substance: Effect on the Rat Ovary (1963) (296)
- Age at menarche. Genetic and environmentalinfluences. (1969) (295)
- FALL IN NOCTURNAL SERUM MELATONIN DURING PREPUBERTY AND PUBESCENCE (1984) (289)
- Melatonin treatment for age-related insomnia. (2001) (282)
- Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial (2010) (281)
- Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System (1964) (272)
- Control of brain neurotransmitter synthesis by precursor availability and nutritional state. (1976) (260)
- Daily rhythm in human urinary melatonin. (1975) (254)
- Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake. (1979) (253)
- Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial. (2012) (252)
- Choline metabolism as a basis for the selective vulnerability of cholinergic neurons (1992) (250)
- Drugs that enhance central serotoninergic transmission diminish elective carbohydrate consumption by rats. (1979) (241)
- Melatonin in human preovulatory follicular fluid. (1987) (237)
- Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. (1993) (232)
- Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats. (1977) (229)
- Effects of melatonin on human mood and performance (1984) (227)
- Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorphine, and DOPA (1980) (226)
- Serotonin 5-HT2a and 5-HT2c Receptors Stimulate Amyloid Precursor Protein Ectodomain Secretion (*) (1996) (222)
- Effects of systemic nicotine on serotonin release in rat brain (1993) (219)
- Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. (1996) (218)
- Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios. (2003) (214)
- INSULIN, PLASMA AMINOACID IMBALANCE, AND HEPATIC COMA (1975) (207)
- Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus. (1982) (203)
- Effect of nutrient intake on premenstrual depression. (1989) (203)
- Physiological control of brain norepinephrine synthesis by brain tyrosine concentration. (1978) (198)
- Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum (1989) (196)
- Daily rhythms in the concentrations of various amino acids in human plasma. (1968) (195)
- Nutrients that modify brain function. (1982) (193)
- The circadian rhythm of plasma melatonin during the normal menstrual cycle and in amenorrheic women. (1988) (186)
- Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. (1995) (185)
- Oral supplementation with docosahexaenoic acid and uridine-5′-monophosphate increases dendritic spine density in adult gerbil hippocampus (2007) (184)
- The site of dopamine formation in rat striatum after L-dopa administration. (1981) (180)
- Nonaminergic striatal neurons convert exogenous l‐dopa to dopamine in parkinsonism (1980) (180)
- Carbohydrates and depression. (1989) (175)
- Control of brain monoamine synthesis by diet and plasma amino acids. (1975) (173)
- The effects of light on the human body. (1975) (170)
- Neurochemical and behavioral consequences of acute, uncontrollable stress: Effects of dietary tyrosine (1984) (167)
- Adrenocortical control of epinephrine synthesis. (1971) (166)
- Relevance of free tryptophan in serum to tissue tryptophan concentrations. (1974) (163)
- Melatonin: a sleep-promoting hormone. (1997) (162)
- Correlation between brain tryptophan and plasma neutral amino acid levels following food consumption in rats (1973) (161)
- THE UPTAKE OF H3-MELATONIN IN ENDOCRINE AND NERVOUS TISSUES AND THE EFFECTS OF CONSTANT LIGHT EXPOSURE. (1964) (161)
- Carbohydrate craving in obese people: Suppression by treatments affecting serotoninergic transmission (1981) (161)
- Serotonin release varies with brain tryptophan levels (1990) (161)
- Participation of Central Noradrenergic Neurons in Arterial Baroreceptor Reflexes in the Rabbit (1971) (158)
- Effect of oral CDP-choline on plasma choline and uridine levels in humans. (2000) (158)
- Improvement of sleep quality by melatonin (1995) (157)
- Oral choline administration to patients with tardive dyskinesia. (1977) (156)
- Tyrosine administration reduces blood pressure and enhances brain norepinephrine release in spontaneously hypertensive rats. (1979) (153)
- A prospective study of sexual development and growth in American girls: the statistics of menarchie. (1976) (152)
- Blood-brain barrier transport of caffeine: dose-related restriction of adenine transport. (1982) (150)
- Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally (2006) (149)
- Binding of melatonin to human and rat plasma proteins. (1972) (146)
- Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture. (1969) (146)
- Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study. (1995) (144)
- Long‐term administration of L‐DOPA does not damage dopaminergic neurons in the mouse (1981) (142)
- Physiological control of brain catechol synthesis by brain tyrosine concentration. (1977) (140)
- Hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland. (1972) (139)
- Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla. (1972) (136)
- Effects of a Low Dose of Melatonin on Sleep in Children with Angelman Syndrome (1999) (135)
- Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. (1976) (133)
- A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat. (1966) (132)
- Regional Uptake of 3H-Melatonin from Blood or Cerebrospinal Fluid by Rat Brain (1969) (130)
- Use of phosphatide precursors to promote synaptogenesis. (2009) (129)
- Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain (1979) (128)
- Melatonin Synthesis in the Hen Pineal Gland and its Control by Light (1964) (128)
- Control of epinephrine synthesis in the adrenal medulla by the adrenal cortex: hormonal specificity and dose-response characteristics. (1966) (128)
- Effects of pinealectomy and of a bovine pineal extract in rats. (1959) (128)
- Treatment of seasonal depression with d-fenfluramine. (1989) (127)
- Monoamine neurotransmitters and the pathophysiology of stroke and central nervous system trauma. (1974) (127)
- LECITHIN CONSUMPTION RAISES SERUM-FREE-CHOLINE LEVELS (1977) (126)
- An animal model of antipsychotic-induced weight gain (2004) (125)
- Mood, performance, and pain sensitivity: changes induced by food constituents. (1982) (124)
- Cerebrospinal fluid levels of amyloid β‐protein in alzheimer's disease: Inverse correlation with severity of dementia and effect of apolipoprotein e genotype (1995) (122)
- Caffeine alters plasma adenosine levels (1997) (122)
- Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland. (1967) (120)
- Efficacy of Melatonin as a Sleep-Promoting Agent (1997) (120)
- d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects. (1985) (119)
- Central control of the pineal gland: visual pathways. (1968) (118)
- d‐Fenfluramine suppresses the increased calorie and carbohydrate intakes and improves the mood of women with premenstrual depression (1990) (118)
- Urinary melatonin rhythms during sleep deprivation in depressed patients and normals. (1977) (117)
- Carbohydrate craving, obesity and brain serotonin (1986) (116)
- Normal plasma choline responses to ingested lecithin (1980) (115)
- Brain Serotonin, Carbohydrate-craving, obesity and depression. (1996) (115)
- Citicoline improves verbal memory in aging. (1996) (114)
- The Effects of Caffeine and Aspirin on Mood and Performance (1987) (113)
- Release of endogenous dopamine from the superfused rabbit retina in vitro: effect of light stimulation (1988) (111)
- Norepinephrine Turnover in the Heart and Spleen of the Cardiomyopathic Syrian Hamster (1975) (111)
- L-Dihydroxyphenylalanine: Effect on S-Adenosylmethionine in Brain (1970) (110)
- Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine. (1976) (110)
- Sexual maturation in contemporary American girls. (1970) (109)
- Lecithin consumption increases acetylcholine concentrations in rat brain and adrenal gland. (1978) (107)
- PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT. (1964) (107)
- Brain H3‐catecholamine metabolism in experimental cerebral ischemia (1975) (106)
- Neurochemical changes following high-dose aspartame with dietary carbohydrates. (1983) (106)
- Stress and the adrenocortical control of epinephrine synthesis. (2002) (106)
- Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices. (1978) (105)
- Serum tryptophan level after carbohydrate ingestion: selective decline in non-albumin-bound tryptophan coincident with reduction in serum free fatty acids. (1973) (105)
- Daily Rhythm in the Noradrenaline Content of Rat Hypothalamus (1968) (104)
- Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine, increases brain phosphatide and synaptic protein levels in gerbils (2007) (101)
- Choline Administration Elevates Brain Phosphorylcholine Concentrations (1982) (101)
- Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha. (1993) (100)
- Genes, stress, and depression. (2005) (99)
- BEHAVIOURAL EFFECTS OF NUTRIENTS (1983) (99)
- MEDIATION BY β‐ADRENERGIC RECEPTORS OF EFFECT OF NOREPINEPHRINE ON PINEAL SYNTHESIS OF [14C]SEROTONIN AND [14C]MELATONIN (1971) (99)
- Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D. (1991) (98)
- Enzymatic conversion of norepinephrine to epinephrine by the brain. (1969) (98)
- Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting. (1973) (97)
- AN INHIBITORY EFFECT OF MELATONIN ON THE ESTROUS PHASE OF THE ESTROUS CYCLE OF THE RODENT. (1964) (97)
- Catecholamine synthesis: physiological coupling to precursor supply. (1986) (96)
- AN EFFECT OF LUTEINIZING HORMONE ON THE FRACTIONAL PERFUSION OF THE RAT OVARY. (1964) (95)
- The Effect of a Carbohydrate‐Rich Beverage on Mood, Appetite, and Cognitive Function in Women With Premenstrual Syndrome (1995) (94)
- AGE AND ENZYME ACTIVITY IN THE HUMAN PINEAL. (1964) (94)
- The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures. (1972) (94)
- Meal composition and plasma amino acid ratios: effect of various proteins or carbohydrates, and of various protein concentrations. (1986) (94)
- Effects of L-dopa on norepinephrine metabolism in the brain. (1971) (93)
- Effect of pharmacological daytime doses of melatonin on human mood and performance (2005) (93)
- Uridine enhances neurite outgrowth in nerve growth factor-differentiated pheochromocytoma cells (2005) (93)
- Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles. (1984) (93)
- Tyrosine administration increases striatal dopamine release in rats with partial nigrostriatal lesions. (1980) (93)
- “Autocannibalism” of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease—A hypothesis (1985) (93)
- Weight gain and withdrawal symptoms after smoking cessation: a preventive intervention using d-fenfluramine. (1991) (92)
- Dietary uridine enhances the improvement in learning and memory produced by administering DHA to gerbils (2008) (90)
- Thyroid function and the cardiac disposition of catecholamines. (1963) (90)
- Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study (1992) (90)
- Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses (2008) (89)
- Prostaglandin E2 Stimulates Amyloid Precursor Protein Gene Expression: Inhibition by Immunosuppressants (1999) (89)
- Daily rhythmic changes in tyrosine transaminase activity of the rat liver. (1967) (89)
- Changes in Brain Levels of Acidic, Basic, and Neutral Amino Acids After Consumption of Single Meals Containing Various Proportions of Protein (1983) (89)
- Endogenous melatonin levels and the fate of exogenous melatonin: age effects. (1998) (88)
- Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. (1982) (87)
- A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. (1987) (87)
- Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. (2008) (87)
- Entrainment of rhythmic melatonin secretion in man to a 12-hour phase shift in the light/dark cycle. (1978) (87)
- The effects of light on man and other mammals. (1975) (87)
- Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients (1990) (86)
- Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth. (1997) (86)
- The mammalian pineal as a neuroendocrine transducer. (1969) (85)
- Brain monoamines and endocrine function. (1971) (85)
- Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. (1988) (85)
- Tyrosine Phosphorylation-dependent Stimulation of Amyloid Precursor Protein Secretion by the m3 Muscarinic Acetylcholine Receptor (*) (1995) (84)
- Control of the rat pineal gland by light spectra. (1972) (84)
- Possible neurologic effects of aspartame, a widely used food additive. (1987) (84)
- Cyclic Adenosine Monophosphate: Stimulation of Melatonin and Serotonin Synthesis in Cultured Rat Pineals (1969) (82)
- Choline biosynthesis by a preparation enriched in synaptosomes from rat brain (1981) (82)
- The Pineal Organ (1977) (82)
- Dietary Carbohydrate Increases Brain Tryptophan and Decreases Free Plasma Tryptophan (1973) (81)
- Effect of chronic corn consumption on serotonin content of rat brain. (1971) (80)
- Interactions of the pineal and exposure to continuous light on organ weights of female rats. (1961) (80)
- Action spectra for effects of light on hydroxyindole-o-methyl transferases in rat pineal, retina and harderian gland. (1972) (80)
- Norepinephrine: Turnover in Rat Brains after Gonadectomy (1968) (79)
- Blindness: Its Relation to Age of Menarche (1964) (79)
- Elevated choline concentration in neonatal plasma. (1980) (79)
- Trans-synaptic induction of adrenomedullary tyrosine hydroxylase activity by choline: evidence that choline administration can increase cholinergic transmission. (1977) (79)
- Entrainment of the Body Temperature Rhythm in Rats: Effect of Color and Intensity of Environmental Light (1973) (79)
- Effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum. (1985) (79)
- Plasma amino acid concentrations in healthy elderly men and women. (1991) (78)
- Mechanism of the daily rhythm in hepatic tyrosine transaminase activity: role of dietary tryptophan. (1968) (78)
- Neuronal Expression of β-Amyloid Precursor Protein Alzheimer Mutations Causes Intracellular Accumulation of a C-terminal Fragment Containing Both the Amyloid β and Cytoplasmic Domains* (1997) (78)
- Melatonin secretion decreases during the proestrous stage of the rat estrous cycle. (1978) (78)
- The fate of C14-dihydroxyphenylalanine (C14-dopa) in the whole mouse. (1970) (77)
- Dopaminergic neurons in the nigro-striatal and mesolimbic pathways: mediation of specific effects of D-amphetamine. (1975) (77)
- Effects of illumination on human nocturnal serum melatonin levels and performance (1993) (77)
- Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline. (1987) (77)
- Possible involvement of nitric oxide in NMDA-induced glutamate release in the rat striatum: an in vivo microdialysis study (1997) (76)
- The 3‐hydroxy‐3‐methylglutaryl co‐enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons (2006) (76)
- Lecithin can suppress tardive dyskinesia. (1978) (75)
- Effect of various oral glucose doses on plasma neutral amino acid levels. (1982) (75)
- Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats. (1984) (75)
- Daily variations in the concentrations of individual amino acids in rat plasma. (1971) (74)
- ASPARTAME: POSSIBLE EFFECT ON SEIZURE SUSCEPTIBILITY (1985) (74)
- CHAPTER 18 – Effects of Light and Visual Stimuli on Endocrine Function (1967) (74)
- Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa. (1974) (74)
- Relationship between environmental light intensity and retina-mediated suppression of rat pineal serotonin-N-acetyl-transferase. (1974) (74)
- Preliminary report of the committee on phototherapy in the newborn infant. (1974) (74)
- Exercise and neuromodulators: choline and acetylcholine in marathon runners. (1992) (74)
- CHANGES IN THE ENZYMATIC SYNTHESIS OF METABOLISM IN THE PINEAL DURING THE ESTROUS CYCLE. (1965) (73)
- Developmental changes in rat blood choline concentration. (1981) (73)
- Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease (2008) (73)
- The effects of dietary neurotransmitter precursors on human behavior. (1985) (73)
- Biomarkers in the diagnosis and management of Alzheimer's disease. (2015) (73)
- Bingeing behavior and plasma amino acids: A possible involvement of brain serotonin in bulimia nervosa (1988) (72)
- Differential effects of insulin resistance on leucine and glucose kinetics in obesity. (1991) (71)
- Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides (2009) (71)
- Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible mediation by brain dopamine. (1974) (71)
- Huntington's disease: Clinical and chemical effects of choline administration (1977) (71)
- The effect of a carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome (1995) (70)
- Piracetam diminishes hippocampal acetylcholine levels in rats. (1981) (70)
- Metabolism of cytidine (5′)-diphosphocholine (cdp-choline) following oral and intravenous administration to the human and the rat (1987) (68)
- Chronic caffeine consumption potentiates the hypotensive action of circulating adenosine. (1983) (68)
- Effect of d-fenfluramine on serotonin release in brains of anaesthetized rats (1989) (67)
- Oral uridine-5′-monophosphate (UMP) increases brain CDP-choline levels in gerbils (2005) (67)
- Prior carbohydrate consumption affects the amount of carbohydrate that rats choose to eat. (1983) (67)
- Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats. (1985) (66)
- Phosphatidylcholine as a precursor of choline for acetylcholine synthesis. (1987) (66)
- TRH immunoreactivity in rat brain regions, spinal cord and pancreas: validation by high-pressure liquid chromatography and thin-layer chromatography (1980) (66)
- Effects of pineal compounds on mammals. (1975) (65)
- Nutrients, neurotransmitter synthesis, and the control of food intake. (1983) (65)
- Effects of oral choline administration on serum and CSF choline levels in patients with Huntington's Disease 1 (1977) (65)
- Light intensity and the control of melatonin secretion in rats. (1981) (65)
- THE DISPOSITION OF CATECHOLAMINES IN THE RAT UTERUS AND THE EFFECT OF DRUGS AND HORMONES. (1964) (64)
- Do carbohydrates affect food intake via neurotransmitter activity? (1988) (64)
- Effects of Catechol‐O‐Methyltransferase Inhibitors and L‐3,4‐Dihydroxyphenylalanine With or Without Carbidopa on Extracellular Dopamine in Rat Striatum (1993) (64)
- Fate of intracisternally injected melatonin in the rat brain. (1973) (64)
- Tryptophan Availability Modulates Serotonin Release from Rat Hypothalamic Slices (1989) (63)
- Choline ingestion increases the resonance of choline-containing compounds in human brain: An in vivo proton magnetic resonance study (1995) (62)
- Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. (1985) (62)
- Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses. (2010) (62)
- Elevation of plasma tyrosine after a single oral dose of L-tyrosine. (1979) (62)
- Diurnal changes in brain noradrenalin. (1968) (62)
- Concentrations of calcitonin and catecholamines in pheochromocytomas, a mucosal neuroma and medullary thyroid carcinoma. (1973) (61)
- Chronic administration of DHA and UMP improves the impaired memory of environmentally impoverished rats (2008) (61)
- Dietary uridine-5′-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats (2007) (61)
- The Medical and biological effects of light (1985) (61)
- Daily rhythm in the accumulation of brain catechol-amines synthesized fom circulating H3-tyrosine. (1970) (61)
- Diurnal variations in plasma concentrations of basic and neutral amino acids and in red cell concentrations of aspartate and glutamate: effects of dietary protein intake. (1984) (61)
- Mechanisms by which quipazine, a putative serotonin receptor agonist, alters brain 5-hydroxyindole metabolism (1976) (61)
- Studies of the 24 hour rhythm of melatonin in man. (1978) (60)
- L-Dopa: Disaggregation of Brain Polysomes and Elevation of Brain Tryptophan (1971) (59)
- A Drosophila Temperature-Sensitive Seizure Mutant in Phosphoglycerate Kinase Disrupts ATP Generation and Alters Synaptic Function (2004) (59)
- Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C. (1997) (59)
- Tyrosine increases blood pressure in hypotensive rats. (1981) (59)
- Species differences in inducibility of phenylethanolamine-N-methyl transferase. (1968) (58)
- Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats. (2005) (58)
- Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate. (1987) (58)
- The slowing of treatment discovery, 1965–1995 (1995) (57)
- Serotonergic neurones are not involved in action of L-dopa in Parkinson's disease (1980) (57)
- Morphologic changes in the pineal parenchyma cells of rats exposed to continuous light or darkness. (1962) (57)
- Dopamine Release in Rat Striatum: Physiological Coupling to Tyrosine Supply (1989) (57)
- Tyrosine: Effects on catecholamine release (1988) (56)
- Dietary cytidine (5′)-diphosphocholine supplementation protects against development of memory deficits in aging rats (2003) (56)
- THYROID STATE AND BRAIN MONOAMINE METABOLISM11 (1975) (56)
- CONTROL OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITY IN THE RAT PINEAL GLAND BY SYMPATHETIC NERVES. (1965) (56)
- Effect of perinatal undernutrition on the metabolism of catecholamines in the rat brain. (1973) (56)
- Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications. (1993) (55)
- Daily rhythms in hepatic polysome profiles and tyrosine transaminase activity: role of dietary protein. (1969) (55)
- A Nutrient Combination that Can Affect Synapse Formation (2014) (55)
- Relation between brain 5-HIAA levels and the release of serotonin into brain synapses. (1977) (55)
- Increase in rat pineal melatonin content following L-Dopa administration (1973) (55)
- Enhancement by Cytidine of Membrane Phospholipid Synthesis (1992) (55)
- Daily Rhythm in Tyrosine Concentration in Human Plasma: Persistence on Low-Protein Diets (1967) (55)
- Efficacies of dexfenfluramine and fluoxetine in preventing weight gain after smoking cessation. (1995) (54)
- Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells (2003) (54)
- Light intensities required to suppress nocturnal melatonin secretion in albino and pigmented rats. (1984) (53)
- Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. (2000) (53)
- Mineral homeostasis in obesity: effects of euglycemic hyperinsulinemia. (1991) (53)
- Melatonin concentrations in the sudden infant death syndrome. (1990) (53)
- Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]. (2005) (53)
- Melatonin Secretion as a Mediator of Circadian Variations in Sleep and Sleepiness (1985) (53)
- Fenfluramine suppresses snack intake among carbohydrate cravers but not among noncarbohydrate cravers (1987) (53)
- Melatonin excretion of man and rats: Effect of time of day, sleep, pinealectomy and food consumption (1975) (52)
- Mediation of Some Effects of Illumination on the Rat Estrous Cycle by the Sympathetic Nervous System (1964) (52)
- Effect of a 5-HT2C serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs (2002) (52)
- Olfactory bulb removal: effects on brain norepinephrine. (1969) (52)
- Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. (1997) (51)
- THE FORMATION, METABOLISM, AND PHYSIOLOGIC EFFECTS OF MELATONIN IN MAMMALS. (1965) (50)
- A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium (2008) (50)
- High-performance liquid chromatography of water-soluble choline metabolites. (1985) (50)
- Oral L‐glutamine increases GABA levels in striatal tissue and extracellular fluid (2007) (50)
- Effects of phentermine on striatal dopamine and serotonin release in conscious rats:In vivo microdialysis study (1998) (50)
- Platelet and vascular function during fish-oil administration. (1986) (50)
- CHAPTER 36 – Diurnal Rhythms in Mammalian Protein Metabolism (1970) (49)
- Tyrosine for the treatment of depression. (1980) (49)
- Stimulation of Phospholipase D Activity in Human Neuroblastoma (LA‐N‐2) Cells by Activation of Muscarinic Acetylcholine Receptors or by Phorbol Esters: Relationship to Phosphoinositide Turnover (1991) (49)
- PHYSIOLOGICAL DEPENDENCE OF BRAIN METHIONINE AND S‐ADENOSYLMETHIONINE CONCENTRATIONS ON SERUM AMINO ACID PATTERN (1974) (49)
- Alterations of Phospholipid Metabolites in Postmortem Brain from Patients with Alzheimer's Disease a (1991) (48)
- Tyrosine administration decreases serum prolactin levels in chronically reserpinized rats. (1979) (48)
- Effects of caffeine on anterior pituitary and thyroid function in the rat. (1980) (48)
- The mechanism by which methiothepin, a putative serotonin receptor antagonist, icnreses brain 5-hydroxyindole levels. (1975) (48)
- Physiological control of melatonin synthesis and secretion: mechanisms, generating rhythms in melatonin, methoxytryptophol, and arginine vasotocin levels and effects on the pineal of endogenous catecholamines, the estrous cycle, and environmental lighting. (1978) (48)
- Increase in hippocampal acetylcholine after choline administration (1977) (48)
- Long-term effects of postnatal 6-hydroxydopamine treatment on tissue catecholamine levels. (1972) (47)
- Uptake of free choline by isolated perfused rat liver. (1980) (47)
- Artificial induction of melatonin rhythms by programmed microinfusion. (1980) (47)
- The pineal organ (Second of two parts). (1977) (47)
- Choline and Its Products Acetylcholine and Phosphatidylcholine (2009) (47)
- Effects of fluoxetine ord-fenfluramine on serotonin release from, and levels in, rat frontal cortex (1990) (47)
- Combined dietary folate, vitamin B-12, and vitamin B-6 intake influences plasma docosahexaenoic acid concentration in rats (2012) (46)
- Dexfenfluramine, Fluoxetine, and Weight Loss Among Female Carbohydrate Cravers (1993) (46)
- Neuroendocrine effects of caffeine. II. Effects on thyrotropin and corticosterone secretion. (1983) (46)
- Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism. (1996) (46)
- Cholinesterases in cerebrospinal fluid Correlations with clinical measures in Alzheimer's disease (1986) (46)
- Environmental lighting and neuroendocrine function: relationship between spectrum of light source and gonadal growth. (1969) (46)
- Stimulation of [ 14 C] tryptophan 5-hydroxylation by norepinephrine and dibutyryl adenosine 3', 5' monophosphate in rat pineal organ cultures. (1971) (45)
- Increased turnover of 3H-norepinephrine in rat brain following castration or treatment with ovine follicle-stimulating hormone. (1969) (45)
- Catecholamines and neurologic diseases. (1975) (45)
- A balanced carbohydrate (1991) (45)
- Increased TRH content of the basal ganglia in Huntington's disease. (1980) (44)
- Blindness and Menarche (1969) (44)
- Self-selection and regulation of protein: carbohydrate ratio in foods adult rats eat. (1984) (44)
- N-methyl-D-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline. (1992) (44)
- A Mg 2+ dependent hydroxyindole O-methyltransferase in rat Harderian gland. (1972) (44)
- Clonidine increases food and protein consumption in rats. (1980) (43)
- Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects. (1981) (43)
- Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases. (1990) (43)
- Control of brain serotonin levels by the diet. (1974) (42)
- Enhancement by choline of the induction of adrenal tyrosine hydroxylase by phenoxybenzamine, 6-hydroxydopamine, insulin or exposure to cold. (1978) (42)
- The ability of certain anorexic drugs to suppress food consumption depends on the nutrient composition of the test diet. (1984) (42)
- Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices. (1997) (42)
- Serotonin, 5-hydroxyindoleacetic acid (5-HIAA), and monoamide oxidase in the bovine median eminence and pituitary gland. (1970) (42)
- Receptor‐coupled Amyloid Precursor Protein Processing a (1993) (42)
- Photic and neural control of indoleamine metabolism in the rat pineal gland. (1968) (42)
- Mechanism of changes in brain norepinephrine levels following olfactory bulb lesions. (1969) (42)
- Effect of ACTH4–10 on the rate of synthesis of [3H]catecholamines in the brains of intact, hypophysectomized and adrenalectomized rats (1975) (42)
- Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria. (1986) (41)
- Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets (2011) (41)
- The Trajectory from Mood to Obesity (2017) (41)
- Chronic administration of UMP ameliorates the impairment of hippocampal-dependent memory in impoverished rats. (2006) (41)
- Dietary supplementation with uridine-5′-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat (2007) (40)
- SEX STEROIDS, CARDIAC 3H-NOREPINEPHRINE, AND TISSUE MONOAMINE OXIDASE LEVELS IN THE RAT. (1963) (40)
- l-Tyrosine ameliorates some effects of lower body negative pressure stress (1995) (40)
- Streptozotocin increases free fatty acids and decreases phospholipids in rat brain (1998) (39)
- Acute effects of oral or parenteral aspartame on catecholamine metabolism in various regions of rat brain. (1986) (39)
- Phosphatidylcholine produced in rat synaptosomes by N-methylation is enriched in polyunsaturated fatty acids. (1985) (38)
- The pineal gland: its possible roles in human reproduction. (1988) (38)
- Short-term variations in diet composition change the pattern of spontaneous motor activity in rats. (1981) (38)
- "Autocannibalism" of membrane choline-phospholipids: physiology and pathology. (1986) (38)
- Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes (1989) (38)
- Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats. (1985) (38)
- Giving Uridine and/or Docosahexaenoic Acid Orally to Rat Dams during Gestation and Nursing Increases Synaptic Elements in Brains of Weanling Pups (2009) (37)
- Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine. (1981) (37)
- Nutrient Imbalances in Depressive Disorders Possible Brain Mechanisms a (1989) (37)
- Effects of L-dopa administration of the concentrations of dopa, dopamine and norepinephrine in various rat tissues. (1973) (37)
- Sucrose consumption early in life fails to modify the appetite of adult rats for sweet foods. (1979) (37)
- Dietary influences on the synthesis of neurotransmitters in the brain. (2009) (37)
- A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects. (1987) (37)
- Effects of fenfluramine and phentermine (fen–phen) on dopamine and serotonin release in rat striatum: in vivo microdialysis study in conscious animals (1998) (37)
- Dopamine: Mediator of Brain Polysome Disaggregation after L-Dopa (1972) (37)
- Regional effects of L-dihydroxyphenylalanine (L-dopa) on norepinephrine metabolism in rat brain. (1972) (37)
- Age-related decreases in melatonin secretion--clinical consequences. (2000) (37)
- Mechanism of changes in brain norepinephrine metabolism after ovariectomy. (1970) (37)
- Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid (2000) (36)
- Effects of systemicl-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens (1988) (36)
- Hepatic tyrosine transaminase rhythm: interaction of environmental lighting, food consumption and dietary protein content. (1969) (36)
- Piracetam: physiological disposition and mechanism of action. (1986) (36)
- Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat. (1981) (36)
- Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines (1999) (36)
- A nutritional approach to ameliorate altered phospholipid metabolism in Alzheimer's disease. (2014) (36)
- 5-Hydroxy-l-tryptophan suppresses food intake in food-deprived and stressed rats (2004) (35)
- Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia (2004) (35)
- Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. (1967) (35)
- Tyrosine for depression. (1982) (35)
- L-Threonine administration increases glycine concentrations in the rat central nervous system. (1980) (34)
- Cytidine and Uridine Increase Striatal CDP-Choline Levels Without Decreasing Acetylcholine Synthesis or Release (2006) (34)
- Fenfluramine and other serotoninergic drugs depress food intake and carbohydrate consumption while sparing protein consumption (1979) (34)
- Tyrosine administration decreases vulnerability to ventricular fibrillation in the normal canine heart. (1981) (34)
- Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. (1997) (34)
- Septohippocampal cholinergic neurons are regulated trans-synaptically by endorphin and corticotropin neuropeptides (1982) (34)
- Ways that foods can affect the brain. (2009) (34)
- Possible contribution of melatonin to the timing of the luteinizing hormone surge. (1987) (34)
- Cereal ingestion and catecholamine excretion. (1974) (34)
- Release of endogenous dopamine from electrically stimulated slices of rat striatum (1984) (33)
- A sensitive and specific isotopic assay for the estimation of tyrosine transaminase. (1968) (32)
- Dihydroxyphenylalanine in Rat Food Containing Wheat and Oats (1972) (32)
- Ramelteon: a novel treatment for the treatment of insomnia (2006) (32)
- Tyrosine availability determines stimulus-evoked dopamine release from rat striatal slices (1985) (32)
- Brain tyrosine level controls striatal dopamine synthesis in haloperidol-treated rats (2005) (32)
- Characteristics of synaptosomal tyrosine uptake in various brain regions: effect of other amino acids. (1981) (32)
- Adrenocortical control of epinephrine synthesis in health and disease. (1971) (32)
- Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein. (1979) (32)
- Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices. (1994) (32)
- The pharmacology of the pineal gland. (1976) (32)
- Oral Cytidine 5′‐Diphosphate Choline Administration to Rats Increases Brain Phospholipid Levels (1993) (32)
- Development of tolerance in rats to the hypothermic effects of D-amphetamine and apomorphine. (1974) (31)
- Nutrients affecting brain composition and behavior. (1987) (31)
- Effects of orally administered cytidine 5'-diphosphate choline on brain phospholipid content. (1992) (31)
- Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells. (1998) (31)
- Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotonenergic drugs (1992) (31)
- Decarboxylation of exogenous L-DOPA in rat striatum after lesions of the dopaminergic nigrostriatal neurons: the role of striatal capillaries (1980) (31)
- Thyrotropin-releasing hormone (TRH) content of rat striatum: Modification by drugs and lesions (1981) (31)
- Dietary Phenylalanine and Brain Function (1988) (31)
- Effect of choline on basal and stimulated acetylcholine release: an in vivo microdialysis study using a low neostigmine concentration (1993) (31)
- Melatonin synthesis by an ectopic pinealoma. (1966) (31)
- Treatment of brain disease with dietary precursors of neurotransmitters. (1977) (31)
- Effect of lateral hypothalamic lesions on uptake of norepinephrine by brain homogenates. (1971) (30)
- D-Amphetamine reduces striatal substance P concentrations by presynaptic release of dopamine (1980) (30)
- Monosodium glutamate neurotoxicity, hyperosmolarity, and blood-brain barrier dysfunction. (1979) (30)
- Rat Brain Phosphatidyl‐N,N‐Dimethylethanolamine Is Rich in Polyunsaturated Fatty Acids (1985) (30)
- Radial maze performance in three strains of mice: role of the fimbria/fornix (1983) (30)
- CHAPTER 6 – The Secretion and Actions of Melatonin (1983) (30)
- Regulation of APP Processing Potential for the Therapeutical Reduction of Brain Amyloid Burden a (1996) (30)
- Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine. (1969) (30)
- Regional distribution of endogenous and parenteral glutamate, aspartate and glutamine in rat brain. (1977) (30)
- The formation, metabolism and physiologic effects of melatonin. (1968) (30)
- Choline and lecithin in brain disorders (1979) (29)
- Presence of Base‐Exchange Activity in Rat Brain Nerve Endings: Dependence on Soluble Substrate Concentrations and Effect of Cations (1988) (29)
- Effects of their nutrient precursors on the synthesis and release of serotonin, the catecholamines, and acetylcholine: implications for behavioral disorders. (1988) (29)
- Melatonin in humans. (1986) (29)
- Selective effects of CGS 10686B, dl-fenfluramine or fluoxetine on nutrient selection (1988) (29)
- Synthesis of DOPA in rat stomach following ingestion of cereals. (1974) (28)
- Catecholamines and neurologic diseases (first of two parts). (1975) (28)
- Narcolepsy and the hypocretins. (2006) (28)
- SOME CLINICAL, BIOCHEMICAL, AND PHYSIOLOGICAL ACTIONS OF THE PINEAL GLAND. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH. (1964) (28)
- Disaggregation of brain polysomes by L-5-hydroxytryptophan: Mediation by serotonin (1973) (28)
- Increased Release of Brain Serotonin Reduces Vulnerability to Ventricular Fibrillation in the Cat (1987) (28)
- Studies on the appetite for carbohydrates in rats and humans. (1982) (28)
- Daily rhythms in tyrosine transaminase and other hepatic enzymes that metabolize amino acids: mechanisms and possible consequences. (1974) (28)
- Effect of (+)‐ or (−)‐enantiomers of fenfluramine or norfenfluramine on nutrient selection by rats (1982) (28)
- Behavioral effects of melatonin treatment in non-human primates. (1998) (28)
- Dietary Treatments That Affect Brain Neurotransmitters (1987) (28)
- Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism. (1998) (28)
- Pituitary Serotonin Content: Effects of Melatonin or Deprivation of Water (1970) (28)
- Decrease in neostriatal blood flow after d-amphetamine administration or electrical stimulation of the substantia nigra (1977) (27)
- L‐Threonine in the Treatment of Spasticity (1991) (27)
- Decreased plasma choline concentrations in marathon runners. (1986) (27)
- Regulation of Amyloid Precursor Protein Release By Protein Kinase C in Swiss 3T3 Fibroblasts a (1993) (27)
- Production of diacylglycerol by exogenous phospholipase C stimulates CTP:phosphocholine cytidylyltransferase activity and phosphatidylcholine synthesis in human neuroblastoma cells. (1991) (27)
- Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells. (1987) (27)
- Synaptic phospholipids and proteins are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally (2006) (27)
- Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Aβ1–40 (2000) (27)
- Regional tyrosine levels in rat brain after tyrosine administration (2005) (27)
- Thyroid state and brain monoamine metabolism. (1975) (27)
- Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats (1985) (27)
- The fate of intracisternally administered norepinephrine-3H in the brain and spinal cord of the rabbit. (1971) (27)
- The decarboxylation of DOPA in the parkinsonian brain: in vivo studies on an animal model. (1980) (26)
- Potentiation by choline of basal and electrically evoked acetylcholine release, as studied using a novel device which both stimulates and perfuses rat corpus striatum (1993) (26)
- Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs. (1968) (26)
- Excretion of catecholamines and catecholamine metabolites in kwashiorkor. (1973) (26)
- CONTROL OF BRAIN 5-HT CONTENT BY DIETARY CARBOHYDRATES (1973) (25)
- Diminished decarboxylation of l-dopa in rat striatum after intrastriatal injections of kainic acid (1980) (25)
- THE PERMISSIVE ROLE OF HYPERTHERMIA IN THE DISAGGREGATION OF BRAIN POLYSOMES BY l‐DOPA OR d‐AMPHETAMINE 1 (1977) (25)
- Methylation of exogenous 3,4-dihydroxyphenylalanine (,dopa)--effects on methyl group metabolism. (1973) (25)
- PARTICIPATION OF DOPAMINE‐ AND SEROTONIN‐RECEPTORS IN THE DISAGGREGATION OF BRAIN POLYSOMES BY l‐DOPA AND l‐5‐HTP (1975) (25)
- Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells. (2007) (25)
- Treatment of Seasonal Affective Disorder with d‐Fenfluramine (1987) (25)
- Regional distribution of neurotransmitter-synthesizing enzymes and substance P within the rat corpus striatum (1978) (24)
- The pineal gland and aldosterone. (1960) (24)
- Choline potentiates the trans-synaptic induction of adrenal tyrosine hydroxylase by reserpine, probably by enhancing the release of acetylcholine. (1977) (24)
- Biological Implications of Artificial Illumination. (1968) (24)
- ENZYMES CATALYZING THE DE NOVO SYNTHESIS OF METHYL GROUPS IN THE BRAIN AND OTHER TISSUES OF THE RAT (1973) (24)
- The pineal as a neuroendocrine transducer. (1980) (24)
- 4‐Aminopyridine Increases Acetylcholine Release Without Diminishing Membrane Phosphatidylcholine (1990) (24)
- Ambiguities in the use of the term "circadian". (1967) (24)
- Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons (1996) (23)
- IN VIVO INHIBITION OF RAT BRAIN PROTEIN SYNTHESIS BY l‐DOPA (1974) (23)
- Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons. (1983) (23)
- The arrest of prolonged estrus in "middle-aged" rats by pineal gland extract. (1961) (23)
- The adrenal medulla may mediate the increase in pineal melatonin synthesis induced by stress, but not that caused by exposure to darkness (2005) (23)
- Corticotropin regulates trans-synaptically the activity of septo-hippocampal cholinergic neurones (1981) (23)
- Brain H-3-catecholamine metabolism in experimental cerebral ischemia. (1975) (23)
- Viral Neoplastic Transformation of Hamster Pineal Cells in vitro: Retention of Enzymatic Function (1966) (23)
- Neural control of dieting (1996) (23)
- Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex. (1990) (23)
- 4 Aromatic Amino Acids in the Brain (2007) (23)
- Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats (2002) (23)
- Steroid induction of phenylethanolamine-N-methyl transferase in adrenomedullary explants: independence of adrenal innervation. (1970) (23)
- Studies on the mechanism by which tyrosine raises urinary catecholamines. (1982) (22)
- Cyclooxygenase-2 mediates platelet-activating factor-induced prostaglandin E2 release from rat primary astrocytes (2003) (22)
- What is leptin for, and does it act on the brain? (1996) (22)
- BLINDNESS: ITS RELATION TO AGE OF MENARCHE. (1964) (22)
- Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson's disease: studies in an animal model. (1982) (22)
- Selection of carbohydrate to protein ratio and correlations with weight gain and body fat in rats allowed three dietary choices. (1991) (21)
- Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine (1999) (21)
- Catecholamines and neurologic diseases (second of two parts). (1975) (21)
- Nutrition and Alzheimer’s disease: pre‐clinical concepts (2009) (21)
- Phenylalanine administration influences dopamine release in the rat's corpus striatum (1988) (21)
- On the use of synthesis inhibitors to estimate brain norepinephrine synthesis in gonadectomized rats. (1969) (21)
- When--and why--should nutritional state control neurotransmitter synthesis? (1979) (21)
- β-endorphin administration increases hippocampal acetylcholine levels (1979) (20)
- Consumption of a high dietary dose of monosodium glutamate fails to affect extracellular glutamate levels in the hypothalamic arcuate nucleus of adult rats (1996) (20)
- Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids (1991) (20)
- Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration (1991) (20)
- Adenosine affects sympathetic neurotransmission at multiple sites in vivo. (1986) (20)
- Differential effect of CDP-choline on brain cytosolic choline levels in younger and older subjects as measured by proton magnetic resonance spectroscopy (1996) (20)
- Tyrosine's pressor effect in hypotensive rats is not mediated by tyramine. (1984) (20)
- Regulation of proteolytic processing of the amyloid beta-protein precursor by first messengers. A novel potential approach for the treatment of Alzheimer's disease. (1995) (20)
- Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes. (1984) (20)
- Distribution of the Adrenaline-forming Enzyme in the Adrenal Gland of a Snake, Xenodon merremii (1967) (20)
- Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine (1984) (20)
- Caffeine potentiates the enhancement by choline of striatal acetylcholine release. (1992) (19)
- Effects of foods on the brain. Possible implications for understanding and treating Tourette syndrome. (1992) (19)
- Effects of Endotoxin on Monoamine Metabolism in the Rat (1972) (19)
- Influence of Feeding Habits and Adrenal Cortex on Diurnal Rhythm of Hepatic Tyrosine Transaminase Activity 1 (1970) (19)
- Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. (2009) (19)
- Lithium and brain choline levels. (1979) (19)
- Effects of systemic or oral ad libitum monosodium glutamate administration on striatal glutamate release, as measured using microdialysis in freely moving rats (1994) (19)
- The role of dietary protein in generating daily rhythms in rat liver tryptophan pyrrolase and tyrosine transaminase. (1973) (19)
- Brain 3 H-catechol synthesis and the vaginal estrous cycle. (1973) (19)
- Nutritional Control of Central Neurotransmitters (1984) (19)
- d-Fenfluramine selectively decreases carbohydrate but not protein intake in obese subjects. (1984) (19)
- Control of brain serotonin by the diet. (1974) (19)
- Relationship between light intensity and the melatonin and drinking rhythms of rats. (1983) (19)
- Tyrosine hydroxylase activity in the heart of the cardiomyopathic syrian hamster. (1977) (18)
- Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells (1998) (18)
- Effect of acute administration of large neutral and other amino acids on urinary excretion of catecholamines1,2. (1982) (18)
- Plasma Amino Acid Imbalance and Hepatic Coma (1977) (18)
- Biogenic amines in the pituitary gland: what is their origin and function? Pituitary indolamines. (1973) (18)
- Effect of Chlorpromazine and Other Drugs on the Disposition of Circulating Melatonin (1966) (18)
- Selection of dietary protein and carbohydrate by rats: Changes with maturation (1986) (18)
- Prevalence of hepatitis B among men admitted to a federal prison. (1982) (18)
- Dietary carbohydrate increases brain tryptophan and decreases serum-free tryptophan (1973) (17)
- UTERINE EPINEPHRINE AND BLOOD FLOW IN PREGNANT AND POSTPARTURIENT RATS. (1963) (17)
- Induction of Epinephrine-forming Enzyme by Glucocorticoids: Steroid Hydroxylation and Inductive Effect (1968) (17)
- Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase (1977) (17)
- Good light and bad. (1970) (17)
- Sex-dependent increase in pineal hydroxyindole-O-methyl transferase activity after a single intraventricular injection of 6-hydroxydopamine to newborn rats. (1973) (17)
- Food consumption, neurotransmitter synthesis, and human behaviour. (1983) (17)
- EPINEPHRINE AND ORGAN BLOOD FLOW: EFFECTS OF HYPERTHYROIDISM, COCAINE, AND DENERVATION. (1964) (17)
- In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway (1987) (16)
- Non-nutritional uses of nutrients. (2011) (16)
- Serotoninergic mechanisms and obesity (1998) (16)
- Effects of dietary amino acids, carbohydrates, and choline on neurotransmitter synthesis. (1988) (16)
- Summary: circulating tryptophan, brain tryptophan, and psychiatric disease. (1979) (16)
- Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy (1993) (16)
- Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes (1999) (16)
- Adenosine strongly potentiates pressor responses to nicotine in rats. (1984) (16)
- Melatonin as a hormone in humans: a history. (1985) (16)
- Changes in blood osmolarity electrolytes, and metabolites among adult rats treated with a neurotoxic dose of MSG. (1981) (16)
- Depression can beget obesity can beget depression. (2015) (16)
- Melatonin in humans: Possible involvement in SIDS, and use in contraceptives (1991) (16)
- The pineal gland: a biological clock. (1966) (16)
- Medial forebrain bundle lesions: blockade of effects of light on rat gonads and pineal. (1967) (16)
- Food constituents affecting normal and abnormal behaviors (1986) (16)
- Platelet-activating factor increases prostaglandin E2 release from astrocyte-enriched cortical cell cultures (2002) (16)
- Effects of systemic L-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens. (1988) (16)
- Elevation of urinary catecholamines and their metabolites following tyrosine administration in humans. (1982) (16)
- Reversed-phase, ion-pair separation of thyrotropin-releasing hormone and some analogs. (1979) (16)
- Stimulation of hydroxyindole-o-methyl transferase activity in hamster pineal glands by blinding or continuous darkness. (1968) (15)
- The effects of tryptophan and tyrosine on human mood and performance. (1984) (15)
- Multiple Sclerosis, Melatonin, and Neurobehavioral Diseases (2017) (15)
- Fibromyalgia and the complex regional pain syndrome: similarities in pathophysiology and treatment. (2010) (15)
- Deanol acetamidobenzoate inhibits the blood‐brain barrier transport of choline (1978) (15)
- Skeletal muscle: reservoir for exogenous L-dopa. (1974) (15)
- The measurement of melatonin in mammalian tissues and body fluids. (1978) (15)
- Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo. (1987) (15)
- Choline production from choline-containing phospholipids: A hypothetical role in Alzheimer's disease and aging (1984) (15)
- Choline content of mothers' milk in Ecuador and Boston. (1982) (15)
- Systemic administration of thyrotropin-releasing hormone enhances striatal dopamine release in vivo (1990) (15)
- Adenosine potentiates sympathomimetic effects of nicotinic agonists in vivo. (1986) (15)
- THE PHYSIOLOGICAL DISPOSITION OF C14-SEROTONIN IN THE RAT UTERUS. (1964) (14)
- Prevention by choline of the depletion of membrane phosphatidylcholine by a cholinesterase inhibitor. (1988) (14)
- Elevation of serum free tryptophan, but not brain tryptophan, by serum nonesterified fatty acids. (1974) (14)
- Effect of cytidine(5′)diphosphocholine (CDP-Choline) on the total urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) by rats and humans (2005) (14)
- Increase in striatal choline acetyltransferase activity after choline administration (1979) (14)
- Impaired Control of Appetite for Carbohydrates in Some Patients with Eating Disorders: Treatment with Pharmacologic Agents (1984) (13)
- Mechanisms whereby nerve growth factor increases diacylglycerol levels in differentiating PC12 cells (1999) (13)
- Nutrition and Brain Neurotransmitters (1979) (13)
- Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents (2005) (13)
- Striatal substance P-like immunoreactivity: characterization of high-performance liquid chromatography and aspects of subcellular distribution and in vitro release by potassium. (1980) (13)
- Exercise, Plasma Composition, and Neurotransmission (1991) (13)
- Evidence for the existence of pyrimidinergic transmission in rat brain (2015) (13)
- How Anticholinergic Drugs Might Promote Alzheimer's Disease: More Amyloid-β and Less Phosphatidylcholine. (2015) (13)
- Inhibition of platelet-activating factor receptors in hippocampal plasma membranes attenuates the inflammatory nociceptive response in rats (2006) (13)
- The Secretion and Effects of Melatonin in Humans (1983) (13)
- Effects of ethanolamine (Etn) administration on Etn and choline (Ch) levels in plasma, brain extracellular fluid (ECF) and brain tissue, and on brain phospholipid levels in rats: an in vivo study. (1996) (12)
- Choline-induced attenuation of morphine analgesia in the rat. (1977) (12)
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- Choline administration to the rat increases urinary catecholamines (2005) (12)
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- Heterogeneous Long Chain Acyl-CoA Synthetases Control Distribution of Individual Fatty Acids in Newly-Formed Glycerolipids of Neuronal Cells Undergoing Neurite Outgrowth (1999) (9)
- Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40). (2000) (9)
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- 808 Regulation of amyloid precursor protein processing and synthesis by receptor-mediated signal transduction (1996) (2)
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- Lack of effect of increased pineal serotonin content on H3-tryptophan uptake (2005) (0)
- 710 – EFFECT OF I.P. CHOLINE INJECTION ON BRAIN ACETYLCHOLINE LEVELS IN RATS (1977) (0)
- Letter: Plasma neutral aminoacids and tryptophan in cirrhosis. (1975) (0)
- 9.15 Biochemistry and Pharmacology of Synaptic Transmission, Fall 2001 (2001) (0)
- Process and composition for increasing blood pressure (1981) (0)
- Alzheimer's and Parkinson's disease: anatomical, pathological and biochemical aspects (1986) (0)
- Use of uridine in combination with choline for treating a mood disorder or an emotional disorder. (1999) (0)
- ORAL MELATONIN IN NEUROLOGICALLY DISABLED CHILDREN. AUTHOR'S REPLY (1998) (0)
- The Effects of Endocrine, Synaptic and Nutritional Inputs on Catecholamine-Containing Neurons (1970) (0)
- RAISING PLASMA TRYPTOPHAN TO SUPRA-PHYSIOLOGICAL LEVELS DOES NOT INCREASE PLASMA PROLACTIN IN HUMANS (1987) (0)
- Antagonism of neutral amino acid (NAA) of the hypothermic effect of d amphetamine (AMP) (1976) (0)
- Effects of Choline-Containing Compounds on Tardive Dyskinesia and Other Movement Disorders (1980) (0)
- NG108-15 hybrid cells take up but do not synthesize serotonin (1987) (0)
- Nutritional and precursor control of brain acetylcholine synthesis. (1978) (0)
- Accelerated Cell Membrane Degradation in Alzheimer’s Disease Brain: Relationship to Amyloid Formation? (1993) (0)
- Contents, Vol. 6, 1970 (1970) (0)
- Advancing Frontiers in Alzheimer's Disease Research (1987) (0)
- Alpha Methyl p Tyrosine and Experimental Stroke (1975) (0)
- Research report Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve (2000) (0)
- DEPAKI ’ MENT OF HEALTH & HUMAN SERVICE ! 3 Public Health (2000) (0)
- Meeting Report (1972) (0)
- 1487 – D-AMPHETAMINE SULFATE INHIBITION OF BRAIN PROTEIN SYNTHESIS IN RATS (1977) (0)
- The Pharmacology of Dexfenfluramine (1996) (0)
- Ingestive Behavior and Neurosciences Chronic Administration of UMP Ameliorates the Impairment of Hippocampal-Dependent Memory in Impoverished Rats 1 Lisa (2006) (0)
- Inhibition of the metabolism of H super 3 -melatonin by phenothiazines. (1968) (0)
- Microsoft Word - HRE231BF.rtf (2008) (0)
- In vivo study on the effects of TRH on dopamine turnover in rat striatum (1989) (0)
- P2-394: Multinutrient approach in Alzheimer's disease: Rationale for combined beneficial effects of nutrients in disease management (2008) (0)
- DAILY RH YTHi1[S IN HEPA TIC POLYSOM1E PROFILES AND TYROSINE TRANSAMINASE ACTIVITY: ROLE OF DIE TARY PROTEIN (0)
- Effects of dexfenfluramine and fluoxetine on weight loss among female carbohydrate cravers (1992) (0)
- Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development , or after exposure to nerve growth factor or A b 1 – 40 (2000) (0)
- Carbohydrate Craving, Obesity, Seasonal Depression and D-Fenfluramine (1988) (0)
- Use of Citicoline, a Source of Blood Choline and Cytidine/Uridine, for Neuroprotection (2006) (0)
- Use of uridine in combination with choline for the treatment of emotional disorders and mood (1999) (0)
- Consuming a Diet Enriched with Choline , UMP , and DHA Improves Memory in Rodents when these Compounds Increase Phospholipids (2008) (0)
- Effects of Exogenous Choline on Acetylcholine and Choline Contents and Release in Striatal Slices (1986) (0)
- AN ANIMAL MODEL OF PHARMACOLOGICAL THERAPY FOR TARDIVE DYSKINESIA USING CHOLINERGIC DRUGS (1979) (0)
- Summary of Symposium (2008) (0)
- AMINO ACIDS AND RESPIRATION (1982) (0)
- Chairman's Closing Remarks (2008) (0)
- 24. A novel approach to study the regulated release of secretory proteins from brain slices (1994) (0)
- Handling of the uridine in combination with choline for the treatment of neurological disorders (1999) (0)
- Neurotransmitters and Phospholipid Metabolism (FY91 AASERT) (1993) (0)
- Biologic rhythms in the body. (1968) (0)
- Oral Choline Adlninistration to Patients with Huntington ' s Disease * (2006) (0)
- Fate of norepinephrine in sympathetic nerons and by cardiovascular drugs. (1968) (0)
- The ‘Autocannibalism’ of Choline-containing Membrane Phopholipids in the Pathogenesis of Alzheimer’s Disease (1986) (0)
- practice applications LETTERS TO THE EDITOR Snacking and Obesity: Urgency of a Definition to Explore such a Relationship (2007) (0)
- Eighth Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging, Zurich, Switzerland. February 17-19, 1995: The Neurobiology of Alzheimer's Disease (1995) (0)
- Suppression of nocturnal melatonin secretion in albino and pigmented rats, by acute exposure to light (1984) (0)
- INCORPORATION OF 14 C-TRYPTOPHAN INTO 14 C-PROTEIN BY CULTURED RAT PINEALS : STIMULATION BY 1-NOREPINEPHRINE (2004) (0)
- Effects of consuming various foods and nutrients on objective and subjective aspects of human performance and behavior (1984) (0)
- Melatonin secretion decreases duri of the rat estrous cycle (norepinephrine/rhythms/chromatography/radioimmunoassay) (2016) (0)
- Possible sites of action of monoamines in hypothalamohypophyseal function. (1971) (0)
- Compositions containing polyunsaturated fatty acids, and methods of use thereof (2006) (0)
- PLATELET-ACTIVATING FACTOR AFFECTS NOCICEPTION IN RATS AT CEREBRAL SITES OF ACTION (2008) (0)
- AUTHORS' REPLY (1979) (0)
- 3.2 Choline and Its Products Acetylcholine and Phosphatidylcholine Choline (2007) (0)
- Conference on Dietary Phenylalanine and Brain Function, May 8–10, 1987, Washington, DC (1988) (0)
- MEDIATION OF SOME EFFECT OF ILLUMINATION ON THE RAT ESTROUS CYCLE BY THE SYMPATHETIC NERVOUS SYSTEM. (1964) (0)
- The role of hypothalamic catecholamines in the regulation of ACTH secretion in the rat (1988) (0)
- Preface (2000) (0)
- Brain catecholamines and blood flow. (1975) (0)
- D-amphetamine administration reduces substance P concentration in the rat striatum. (1978) (0)
- Brain Phospholipids and their Metabolites in Alzheimer’s Disease: Possible Role of “Auto-Cannibalism” and Implications for Drug Development (1991) (0)
- A PLASMA PHOSPHOLIPID BIOMARKER PROFILE FOR DETECTING PRECLINICAL ALZHEIMER'S DISEASE CAN BE MODIFIED BY ORAL INTAKE OF NUTRIENTS THAT INCREASE PHOSPHOLIPID SYNTHESIS (2014) (0)
- ffects of electrical stimulation and choline availability on the release " and contents of acetylcholine and choline in superfused slices jrom rat striatum (0)
- Remote ambulaltory data acquisition with internet transfer of large EEG/ sleep files for replay and analysis during a pilot melatonin drug studies (1995) (0)
- Effect of Chronic d-Fenfluramine pretreatment on frontal cortex serotonin levels and release. Study with in vivo microdialysis of anesthetized rats (1989) (0)
- A Method of Measuring Extracellular GABA Levels in Rat Striatum (2006) (0)
- USE OF CHOLINE-CONTAINING COMPOUNDS TO INCREASE ACETYLCHOLINE SYNTHESIS AND TREAT NEUROLOGICAL AND PSYCHIATRIC DISORDERS (1984) (0)
- Melatonin's Conflict, Safety Issues (1995) (0)
- Decreased BrainCholineUptake in OlderAdults An In Vivo Proton Magnetic Resonance Spectroscopy Study (2007) (0)
- Involvement of Nutrients in the Pathogenesis or Management of Alzheimer’s Disease (2011) (0)
- EFFECTS OF A LOW DOSE OF MELATONIN ON (2003) (0)
- Composition anti-stress (2001) (0)
- Advances in endocrinology. (1967) (0)
- Research strategies for assessing the behavioral effects of food and nutrients. Introduction. (1982) (0)
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