Stephen D. Levene
American biophysicist
Stephen D. Levene's AcademicInfluence.com Rankings
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Physics
Stephen D. Levene's Degrees
- PhD Biophysics University of California, San Diego
- Masters Physics University of California, San Diego
- Bachelors Physics University of California, San Diego
Why Is Stephen D. Levene Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephen Levene is an American biophysicist and professor of bioengineering, molecular biology, and physics at the University of Texas at Dallas. Early life and education Levene was born in New York City and attended Horace Mann School and Andrew Hill High School in San Jose, California. He received his A.B. in Chemistry from Columbia University and his Ph.D. in Chemistry from Yale University. His doctoral work demonstrated and quantified the phenomenon of sequence-directed bending in DNA due to adenine-thymine tracts, and pioneered the use of Monte Carlo simulation to compute cyclization probabilities of DNA molecules having arbitrary preferred geometries. Upon leaving Yale, Levene became an American Cancer Society postdoctoral fellow at UC San Diego with Bruno Zimm, where he worked on the physical mechanism of gel electrophoresis.
Stephen D. Levene's Published Works
Published Works
- Normal human chromosomes have long G-rich telomeric overhangs at one end. (1997) (694)
- Bent helical structure in kinetoplast DNA. (1982) (456)
- Conformational and thermodynamic properties of supercoiled DNA. (1992) (359)
- Telomere Shortening Is Proportional to the Size of the G-rich Telomeric 3′-Overhang* (2000) (274)
- DNA bending, flexibility, and helical repeat by cyclization kinetics. (1992) (201)
- Separations of open-circular DNA using pulsed-field electrophoresis. (1987) (129)
- Problems and prospects in the theory of gel electrophoresis of DNA (1992) (121)
- Bending and flexibility of kinetoplast DNA. (1986) (102)
- Ring closure probabilities for DNA fragments by Monte Carlo simulation. (1986) (97)
- Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes. (1995) (84)
- Statistical-mechanical theory of DNA looping. (2006) (79)
- A computer graphics study of sequence-directed bending in DNA. (1983) (77)
- Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens (2017) (71)
- Analysis of In-Vivo LacR-Mediated Gene Repression Based on the Mechanics of DNA Looping (2006) (66)
- A bent helix in kinetoplast DNA. (1983) (65)
- Functional 20S proteasomes in mature human red blood cells (2011) (59)
- Topological distributions and the torsional rigidity of DNA. A Monte Carlo study of DNA circles. (1986) (58)
- DNA topology and geometry in Flp and Cre recombination. (2006) (55)
- Understanding the anomalous electrophoresis of bent DNA molecules: a reptation model. (1989) (52)
- Fractionation of SWNT/nucleic acid complexes by agarose gel electrophoresis (2006) (47)
- Analysis of the structure of dimeric DNA catenanes by electron microscopy. (1995) (39)
- Single DNA conformations and biological function (2006) (35)
- DNA-sequence asymmetry directs the alignment of recombination sites in the FLP synaptic complex. (1999) (23)
- Supercoiling-dependent flexibility of adenosine-tract-containing DNA detected by a topological method. (1997) (21)
- Gel mobilities of linking-number topoisomers and their dependence on DNA helical repeat and elasticity. (2010) (20)
- The thermodynamics of DNA loop formation, from J to Z. (2013) (19)
- Measurements of DNA-loop formation via Cre-mediated recombination (2012) (17)
- Contribution of fluorophore dynamics and solvation to resonant energy transfer in protein-DNA complexes: a molecular-dynamics study. (2014) (16)
- Kinetic pathways of topology simplification by Type-II topoisomerases in knotted supercoiled DNA (2018) (11)
- Analysis of DNA knots and catenanes by agarose-gel electrophoresis. (1999) (11)
- Analysis of DNA topoisomers, knots, and catenanes by agarose gel electrophoresis. (2009) (9)
- Generation of leukotrienes from fetal and neonatal porcine blood vessels. (1986) (8)
- Cloning of human purine-nucleoside phosphorylase cDNA sequences by complementation in Escherichia coli (polysome immunoadsorption/cDNA cloning/phenotypic expression/genetic disease/immunodeficiency) (8)
- Free-energy calculations for semi-flexible macromolecules: applications to DNA knotting and looping. (2014) (7)
- Deconvolution of nucleic-acid length distributions: a gel electrophoresis analysis tool and applications (2019) (7)
- Human umbilical arteries and veins: generation of leukotrienes and response to exogenous leukotrienes. (1987) (7)
- Electrophoretic Fractionation of Carbon Nanotube Dispersions on Agarose Gels (2007) (6)
- Theories of pulsed-field gel electrophoresis. (1992) (6)
- Analysis of chemical and enzymatic cleavage frequencies in supercoiled DNA. (2004) (5)
- Conformation and Energetics of Supercoiled DNA: Experimental and Theoretical Studies (1994) (4)
- DNA-Topology Simplification by Topoisomerases (2021) (4)
- Understanding DNA Looping Through Cre-Recombination Kinetics (2014) (3)
- Beyond the Linear Genome: Comprehensive Determination of the Endogenous Circular Elements in C. elegans and Human Genomes via an Unbiased Genomic-Biophysical Method (2017) (3)
- PCR-BASED SYNTHESIS OF REPETITIVE SINGLE-STRANDED DNA FOR APPLICATIONS TO NANOBIOTECHNOLOGY (2005) (2)
- Structural aspects of RecA-dependent homologous strand exchange involving human telomeric DNA. (2005) (2)
- Introduction to DNA Topology (2014) (2)
- Loop-closure kinetics reveal a stable, right-handed DNA intermediate in Cre recombination (2019) (2)
- DNA/RNA Flexibility (2002) (2)
- DNA cyclization and looping in the wormlike limit: Normal modes and the validity of the harmonic approximation (2015) (2)
- Evaluating Partition Functions for Multiscale Models of DNA(Statistical Physics and Topology of Polymers with Ramifications to Structure and Function of DNA and Proteins) (2011) (1)
- Topology in Biology: From DNA Mechanics to Enzymology (2007) (1)
- Nick Cozzarelli: A Personal Remembrance (2009) (1)
- Multipoles as Force Field Parameters-Accuracy and Redundancy (2014) (0)
- Circulomics: Ultrasensitive Characterization of Extrachromosomal Circular DNA (eccDNA) Distributions and Functions in Eukaryotes (2018) (0)
- Erratum: Supercoiling-dependent flexibility of adenosine-tract- containing DNA detected by a topological method (Proceedings of the National Academy of Science (April 1, 1997) 94:7 (2817-2822)) (1997) (0)
- Quantitative Characterization of Gel Electrophoresis Images (2018) (0)
- Quantitation of Surface-Conjugated DNA Density for Single-Molecule Applications (2018) (0)
- DNA Bending and Protein-DNA Interactions (1983) (0)
- Microarray-Based Hybridization Technology for Biosensors (2008) (0)
- Engineering Multiple Site-Specific Modifications in Supercoiled DNAs (2012) (0)
- Bulge defects do not destabilize negatively supercoiled DNA. (2005) (0)
- Topology-Dependent Dynamics of Single DNA Molecules (2018) (0)
- Investigating Cre-Recombinase-Mediated DNA Looping using FRET (2014) (0)
- Closing the Loop on Protein-DNA Interactions: Interplay Between Shape and Flexibility in Nucleoprotein Assemblies Having Implications for Biological Regulation (2009) (0)
- Kinetics of topological transitions in DNA mediated by topoisomerases and recombinases (2022) (0)
- A “shallow-learning” model identifies target-sequence preferences for DNA fragmentation and tagging by Nextera (Tn5) “tagmentase” (2022) (0)
- Circulomics: The Structural Genomics of Endogenous and Exogenous Extrachromosomal Circular DNAs (2018) (0)
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