Wolfram Bode
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German biochemist
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Why Is Wolfram Bode Influential?
(Suggest an Edit or Addition)According to Wikipedia, Wolfram Bode is a German biochemist. Biography Born in Berlin, Bode was educated in chemistry and biochemistry at the University of Göttingen, the University of Tübingen and the University of Munich as a fellow of the Studienstiftung des deutschen Volkes. He obtained his Ph.D. in 1971 at the University of Munich for studies of the bacterial flagellum. Since 1972 he is working at the Max Planck Institute of Biochemistry in Martinsried. Bode is associate professor at the University of Munich.
Wolfram Bode's Published Works
Published Works
- Natural protein proteinase inhibitors and their interaction with proteinases. (1992) (979)
- The cystatins: Protein inhibitors of cysteine proteinases (1991) (778)
- The refined 1.9 A crystal structure of human alpha‐thrombin: interaction with D‐Phe‐Pro‐Arg chloromethylketone and significance of the Tyr‐Pro‐Pro‐Trp insertion segment. (1989) (747)
- Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc‐binding environments (HEXXHXXGXXH and Met‐turn) and topologies and should be grouped into a common family, the ‘metzincins’ (1993) (700)
- The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases (1995) (665)
- The structure of a complex of recombinant hirudin and human alpha-thrombin. (1990) (646)
- Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1 (1997) (606)
- Structural basis of the activation and action of trypsin (1978) (599)
- The refined 1.9‐Å X‐ray crystal structure of d‐Phe‐Pro‐Arg chloromethylketone‐inhibited human α‐thrombin: Structure analysis, overall structure, electrostatic properties, detailed active‐site geometry, and structure‐function relationships (1992) (583)
- The 2.0 A X‐ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. (1988) (530)
- The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors (1983) (507)
- Handbook of metalloproteins (2006) (499)
- Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. (1974) (488)
- The refined 2.4 A X‐ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. (1990) (450)
- A player of many parts: the spotlight falls on thrombin's structure. (1993) (397)
- The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0. (1975) (385)
- The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. (2000) (363)
- Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors. (1989) (355)
- Structure of human des(1-45) factor Xa at 2.2 A resolution. (1993) (347)
- Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. (1998) (342)
- Crystal structure of the complex formed by the membrane type 1‐matrix metalloproteinase with the tissue inhibitor of metalloproteinases‐2, the soluble progelatinase A receptor (1998) (333)
- Refined structure of the hirudin-thrombin complex. (1991) (325)
- Structural properties of matrix metalloproteinases (1999) (320)
- X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. (1985) (317)
- Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex (2000) (305)
- Crystal structure of the thrombin‐hirudin complex: a novel mode of serine protease inhibition. (1990) (299)
- The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution. (1978) (283)
- Inflammation, sepsis, and coagulation. (1999) (282)
- The X‐ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. (1994) (281)
- The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism (2003) (278)
- Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. (1987) (275)
- Structural basis of the endoproteinase-protein inhibitor interaction. (2000) (272)
- Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases (1992) (270)
- X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. (1995) (258)
- X‐ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. (1986) (245)
- Structural features of a superfamily of zinc-endopeptidases: the metzincins. (1995) (240)
- Human β-tryptase is a ring-like tetramer with active sites facing a central pore (1998) (239)
- Crystal structures of the membrane-binding C2 domain of human coagulation factor V (1999) (238)
- Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation (2003) (228)
- Structural basis for the activation of human procaspase-7 (2001) (223)
- Crystal structure analysis and refinement at 2.5 A of hexameric C-phycocyanin from the cyanobacterium Agmenellum quadruplicatum. The molecular model and its implications for light-harvesting. (1986) (219)
- The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis Structural analysis, subtilisin structure and interface geometry (1987) (213)
- The 2.8 A crystal structure of Gla‐domainless activated protein C. (1996) (209)
- Primary structure of human neutrophil elastase. (1987) (207)
- Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. (1977) (204)
- Insights into MMP‐TIMP Interactions (1999) (203)
- Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. (1974) (202)
- X-ray Structure of Active Site-inhibited Clotting Factor Xa (1996) (201)
- Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin. (1983) (198)
- On the disordered activation domain in trypsinogen: chemical labelling and low‐temperature crystallography (1982) (196)
- The 2.5 A X‐ray crystal structure of the acid‐stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha‐chymotrypsin. (1988) (186)
- The crystal structure of the proprotein processing proteinase furin explains its stringent specificity (2003) (186)
- The ornithodorin‐thrombin crystal structure, a key to the TAP enigma? (1996) (185)
- The interaction of thrombin with fibrinogen. A structural basis for its specificity. (1992) (185)
- Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. (1985) (185)
- First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases. (1993) (182)
- The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. II. The binding of the pancreatic trypsin inhibitor and of isoleucine-valine and of sequentially related peptides to trypsinogen and to p-guanidinobenzoate-trypsinogen. (1979) (180)
- Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibit (1983) (176)
- The crystal structure of the proprotein processing proteinase furin explains its stringent specificity (2003) (168)
- Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. (1992) (168)
- Tachylectin‐2: crystal structure of a specific GlcNAc/GalNAc‐binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus (1999) (166)
- Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. (1995) (164)
- Crystal structure of gingipain R: an Arg‐specific bacterial cysteine proteinase with a caspase‐like fold (1999) (164)
- The clot thickens: clues provided by thrombin structure. (1995) (163)
- The refined 2.0 Å X‐ray crystal structure of the complex formed between bovine β‐trypsin and CMTI‐I, a trypsin inhibitor from squash seeds (Cucurbita maxima) Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes (1989) (163)
- Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity. (2005) (157)
- Structural Basis of the Matrix Metalloproteinases and Their Physiological Inhibitors, the Tissue Inhibitors of Metalloproteinases (2003) (156)
- Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors. (1995) (155)
- Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins. (1991) (147)
- The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems (2001) (144)
- Mechanism of inhibition of papain by chicken egg white cystatin (1989) (144)
- Refined three-dimensional structure of phycoerythrocyanin from the cyanobacterium Mastigocladus laminosus at 2.7 A. (1990) (143)
- Specificity Profiling of Seven Human Tissue Kallikreins Reveals Individual Subsite Preferences* (2006) (143)
- The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain. (1996) (139)
- X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. (1995) (138)
- The 1.8 A crystal structure of human cathepsin G in complex with Suc‐Val‐Pro‐PheP‐(OPh)2: a Janus‐faced proteinase with two opposite specificities. (1996) (137)
- The ternary microplasmin–staphylokinase–microplasmin complex is a proteinase–cofactor–substrate complex in action (1998) (136)
- Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug. (1997) (133)
- Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin. (1994) (132)
- Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases. (1982) (130)
- Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor. (1995) (128)
- Induction of the bovine trypsinogen—trypsin transition by peptides sequentially similar to the N‐terminus of trypsin (1976) (128)
- Structure of astacin with a transition-state analogue inhibitor (1996) (128)
- The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator. (1996) (128)
- Refined 1.2 A crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c. Molecular structure of eglin and its detailed interaction with subtilisin. (1986) (125)
- Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin. (1994) (124)
- The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution. (1994) (121)
- The 1.9-Å crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link (2002) (120)
- Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases (1994) (116)
- Properties of purified gut trypsin from Helicoverpa zea, adapted to proteinase inhibitors. (2002) (114)
- Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. (1999) (114)
- Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity. (2007) (113)
- Inhibition of Furin by Polyarginine-containing Peptides (2004) (112)
- Catalytic Domain Structures of MT-SP1/Matriptase, a Matrix-degrading Transmembrane Serine Proteinase* (2002) (112)
- Activation of snake venom metalloproteinases by a cysteine switch‐like mechanism (1993) (111)
- Structure and interaction modes of thrombin. (2006) (110)
- The 1.8-Å Crystal Structure of a Matrix Metalloproteinase 8-Barbiturate Inhibitor Complex Reveals a Previously Unobserved Mechanism for Collagenase Substrate Recognition* (2001) (108)
- Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). (1995) (107)
- A helping hand for collagenases: the haemopexin-like domain. (1995) (104)
- Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases. (2000) (102)
- Lysine 156 promotes the anomalous proenzyme activity of tPA: X‐ray crystal structure of single‐chain human tPA (1997) (101)
- The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases. (1998) (101)
- Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases (2003) (101)
- The crystal and molecular structure of the third domain of silver pheasant ovomucoid (OMSVP3). (1985) (101)
- The single calcium‐binding site of crystalline bovine β‐trypsin (1975) (100)
- Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases. (1993) (96)
- Changing Residue 338 in Human Factor IX from Arginine to Alanine Causes an Increase in Catalytic Activity* (1998) (94)
- Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. (2001) (94)
- Crystal structure of bovine trypsinogen at 1-8 A resolution. I. Data collection, application of patterson search techniques and preliminary structural interpretation. (1976) (93)
- Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. (2006) (93)
- Comparative Analysis of Haemostatic Proteinases: Structural Aspects of Thrombin, Factor Xa, Factor IXa and Protein C (1997) (92)
- Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. (2008) (90)
- The C‐terminal (haemopexin‐like) domain structure of human gelatinase A (MMP2): structural implications for its function (1996) (90)
- X-ray Structure of Human proMMP-1 (2005) (90)
- Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. (1998) (90)
- Specific inhibition of insect α-amylases: yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolution (1999) (87)
- Thrombin as a multifunctional protein: induction of cell adhesion and proliferation. (1992) (86)
- Geometry of binding of the benzamidine- and arginine-based inhibitors Nα-(2-naphthyl-sulphonyl-glycyl)-dl-p-amidinophenylalanyl-piperidine (NAPAP) and (2R,4R)-4-methyl-1-[Nα-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulphonyl)-l-arginyl]-2-piperidine carboxylic acid (MQPA) to human α-thrombin (1990) (86)
- Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 A resolution. (1998) (85)
- The thrombin E192Q–BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin (1997) (85)
- Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. (1996) (84)
- Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin (1995) (84)
- Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. (2006) (84)
- The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region. (2002) (83)
- Increase in gelatinase-specificity of matrix metalloproteinase inhibitors correlates with antimetastatic efficacy in a T-cell lymphoma model. (2002) (82)
- The metzincin-superfamily of zinc-peptidases. (1996) (82)
- Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. (1998) (82)
- Divining the serpin inhibition mechanism: a suicide substrate 'springe'? (1995) (82)
- Design and synthesis of heterotrimeric collagen peptides with a built‐in cystine‐knot Models for collagen catabolism by matrix‐metalloproteases (1996) (82)
- Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7 (2008) (82)
- The human mast cell tryptase tetramer: a fascinating riddle solved by structure. (2000) (81)
- Structural basis of the zinc inhibition of human tissue kallikrein 5. (2007) (81)
- The 0.25-nm X-ray structure of the Bowman-Birk-type inhibitor from mung bean in ternary complex with porcine trypsin. (1993) (81)
- Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor. (1996) (81)
- Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution. (1998) (80)
- Electrostatic interactions in the association of proteins: An analysis of the thrombin–hirudin complex (1992) (79)
- Identification of functionally important amino acid residues within the C2-domain of human factor V using alanine-scanning mutagenesis. (2000) (78)
- Ligand binding: proteinase-protein inhibitor interactions (1991) (78)
- Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family (1998) (77)
- The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor. (1984) (76)
- Conformational variability of chicken cystatin. Comparison of structures determined by X-ray diffraction and NMR spectroscopy. (1993) (76)
- Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2 (2000) (76)
- The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. (1997) (75)
- Residue 2 of TIMP-1 Is a Major Determinant of Affinity and Specificity for Matrix Metalloproteinases but Effects of Substitutions Do Not Correlate with Those of the Corresponding P1′ Residue of Substrate* (1999) (75)
- Chymotryptic specificity determinants in the 1.0 Å structure of the zinc-inhibited human tissue kallikrein 7 (2007) (75)
- The structure of thrombin: a janus-headed proteinase. (2006) (73)
- A standard orientation for metallopeptidases. (2012) (73)
- The structure of the human betaII-tryptase tetramer: fo(u)r better or worse. (1999) (73)
- The refined crystal structure of bovine β-trypsin at 1·8 Å resolution (1975) (72)
- The refined 2.3 Å crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor (1988) (72)
- The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry. (1987) (71)
- Structural basis for the sheddase function of human meprin β metalloproteinase at the plasma membrane (2012) (70)
- The Three-dimensional Structure of Recombinant Leech-derived Tryptase Inhibitor in Complex with Trypsin (1997) (69)
- Crystal structure of the human α‐thrombin–haemadin complex: an exosite II‐binding inhibitor (2000) (68)
- Crystallization, crystal structure analysis and molecular model of the third domain of Japanese quail ovomucoid, a Kazal type inhibitor. (1981) (68)
- Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants (1997) (67)
- Structural Mapping of the Active Site Specificity Determinants of Human Tissue-type Plasminogen Activator (1997) (66)
- Engineering of Selective TIMPs (1999) (64)
- Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity. (2004) (64)
- Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. (2002) (64)
- Fibrinogen Substrate Recognition by Staphylocoagulase·(Pro)thrombin Complexes* (2006) (63)
- Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. (2002) (63)
- Crystal Structure of the Caspase Activator Human Granzyme B, a Proteinase Highly Specific for an Asp-P1 Residue (2000) (63)
- Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution. (1992) (63)
- 1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile. (1997) (63)
- Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity. (1994) (62)
- Identification of a β-Secretase Activity, Which Truncates Amyloid β-Peptide after Its Presenilin-dependent Generation* (2003) (61)
- Coagulation factors and their inhibitors. (1994) (61)
- Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors. (2005) (61)
- Crystal structure of the apoptosis-inducing human granzyme A dimer (2003) (61)
- (4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. (2000) (60)
- HUMAN CATHEPSIN G (1997) (59)
- The 2.2-Å Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features* (2002) (59)
- Structure and Biology of the Globular Domain of Basement Membrane Type IV Collagen a (1985) (58)
- Structural aspects of serpin inhibition (1994) (57)
- Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes. (1991) (57)
- The three‐dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C. (1995) (56)
- 1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase. (2004) (55)
- The staphylocoagulase family of zymogen activator and adhesion proteins (2004) (55)
- Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV. (2006) (54)
- The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain (2010) (54)
- Structural Basis for Possible Calcium-Induced Activation Mechanisms of Calpains (2001) (53)
- Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR) (2006) (51)
- The cysteine proteinase inhibitor chicken cystatin is a phosphoprotein (1989) (50)
- Structural basis of matrix metalloproteinase function. (2003) (50)
- The structure of calcium-free human m-calpain: implications for calcium activation and function. (2001) (50)
- Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2. (2007) (49)
- Crystal structure analysis and refinement of two variants of trigonal trypsinogen (1978) (46)
- Nuclear magnetic resonance solution and X-ray structures of squash trypsin inhibitor exhibit the same conformation of the proteinase binding loop. (1989) (45)
- Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage. (1997) (44)
- Bivalent inhibition of human β-tryptase (2001) (44)
- Horseshoe Grab Coagulogen Is an Invertebrate Protein with a Nerve Growth Factor-Like Domain (1997) (44)
- New enzyme lineages by subdomain shuffling. (1998) (43)
- The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis (2003) (43)
- Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols (1997) (43)
- The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase. (2002) (43)
- The X-ray crystal structure analysis of the refined complex formed by bovine trypsin and p-amidinophenylpyruvate at 1.4 A resolution. (1983) (43)
- Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera. (2001) (42)
- Endoproteinase‐protein inhibitor interactions (1999) (42)
- Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain. (2007) (41)
- The primary structure of bdellin B-3 from the leech Hirudo medicinalis. Bdellin B-3 is a compact proteinase inhibitor of a "non-classical" Kazal type. It is present in the leech in a high molecular mass form. (1986) (41)
- Crystal structure of the catalytic domain of MMP-16/MT3-MMP: characterization of MT-MMP specific features. (2004) (41)
- The covalent structure of the elastase inhibitor from Anemonia sulcata--a "non-classical" Kazal-type protein. (1987) (39)
- Physiological fIXa Activation Involves a Cooperative Conformational Rearrangement of the 99-Loop* (2003) (39)
- The structure of thrombin, a chameleon‐like proteinase (2005) (39)
- Design of benzamidine-type inhibitors of factor Xa. (1998) (39)
- Crystal structure of the E. coli dipeptidyl carboxypeptidase Dcp: further indication of a ligand-dependent hinge movement mechanism. (2005) (38)
- Structure of malonic acid‐based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data (1998) (37)
- The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket. (2005) (36)
- Novel Fluorescent Prothrombin Analogs as Probes of Staphylocoagulase-Prothrombin Interactions* (2006) (36)
- An active zymogen: unravelling the mystery of tissue-type plasminogen activator. (1998) (35)
- Thermodynamic Linkage between the S1 Site, the Na+ Site, and the Ca2+ Site in the Protease Domain of Human Activated Protein C (APC) (2002) (35)
- Proteinase inhibitors from the European medicinal leech Hirudo medicinalis: structural, functional and biomedical aspects. (1995) (35)
- Tissue-type plasminogen activator: variants and crystal/solution structures demarcate structural determinants of function. (1997) (35)
- Proteinase-protein inhibitor interaction. (1991) (34)
- The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity. (1999) (34)
- X‐ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors (1995) (34)
- X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases. (2003) (33)
- Thrombin inhibitors identified by computer-assisted multiparameter design. (2005) (33)
- Structural Studies on MMPs andTIMPs Wolfram Bode and Klaus Maskos (2001) (33)
- Expression, Purification, Characterization, and X-Ray Analysis of Selenomethionine 215 Variant of Leukocyte Collagenase (1997) (30)
- Spatial structure of thrombin as a guide to its multiple sites of interaction. (1993) (30)
- The influence of residue 190 in the S1 site of trypsin‐like serine proteases on substrate selectivity is universally conserved (2002) (30)
- Mechanism of interaction of cysteine proteinases and their protein inhibitors as compared to the serine proteinase-inhibitor interaction. (1990) (30)
- The structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor (1975) (30)
- Expression of the glyceraldehyde‐3‐phosphate dehydrogenase gene from the extremely thermophilic archaebacterium Methanothermus fervidus in E. coli (1988) (29)
- X-ray Structure of Human proMMP-1 NEW INSIGHTS INTO PROCOLLAGENASE ACTIVATION AND COLLAGEN BINDING* (2005) (29)
- Determination of the protein content of crystals formed by Mastigocladus laminosus C-phycocyanin, Chroomonas spec. phycocyanin-645 and modified human fibrinogen using an improved Ficoll density gradient method. (1985) (29)
- Fine Mapping of Inhibitory Anti-factor V Antibodies Using Factor V C2 Domain Mutants (2001) (29)
- Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation. (1997) (26)
- Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*). (1991) (26)
- Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors. (2003) (26)
- Interaction of human alpha 1-proteinase inhibitor with chymotrypsinogen A and crystallization of a proteolytically modified alpha 1-proteinase inhibitor. (1982) (26)
- The 2.2 .ANG. resolution x-ray crystal structure of the complex of trypsin inhibited by 4-chloro-3-ethoxy-7-guanidinoisocoumarin: a proposed model of the thrombin-inhibitor complex (1990) (25)
- Crystal structures of thrombin and thrombin complexes as a framework for antithrombotic drug design (1994) (24)
- Structural studies on MMPs and TIMPs. (2001) (24)
- X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition (2006) (24)
- Impact of protein-protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear magnetic resonance solution structure of hirudin(1-51). (1992) (24)
- Low‐temperature protein crystallography. Effect on flexibility, temperature factor, mosaic spread, extinction and diffuse scattering in two examples: bovine trypsinogen and Fc fragment (1980) (23)
- The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop. (1999) (23)
- The structure of γ‐N‐methylasparagine in C‐phycocyanin from Mastigocladus laminosus and Agmenellum quadruplicatum (1988) (23)
- Macrocyclic Statine‐Based Inhibitors of BACE‐1 (2007) (21)
- Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor. (2002) (21)
- Crystallization of phycoerythrocyanin from the cyanobacterium Mastigocladus laminosus and preliminary characterization of two crystal forms. (1985) (21)
- Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines. (1999) (21)
- Thrombin-induced fibrinopeptide release from a fibrinogen variant (fibrinogen Sydney I) with an Aalpha Arg-16----His substitution. (2008) (20)
- A model for the specificity of fibrinogen cleavage by thrombin. (1993) (19)
- Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system. (1999) (19)
- Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). (2008) (18)
- Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydro-8- quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-t (1990) (18)
- Proteinase — Protein inhibitor interactions (1994) (18)
- Identification of a Hydrophobic Exosite on Tissue Type Plasminogen Activator That Modulates Specificity for Plasminogen* (1997) (18)
- Structural Basis for Reduced Staphylocoagulase-mediated Bovine Prothrombin Activation* (2006) (18)
- Synthesis of a (desSer1 Ile29 Leu89) chicken cystatin gene, expression in E. coli as fusion protein and its isolation (1989) (18)
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- On the aggregation of fibrinogen molecules. (1983) (17)
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- X-Ray Crystal Structures of Human α-Thrombin and of the Human Thrombin-Hirudin Complex (1992) (16)
- STRUCTURAL STUDIES ON THE PANCREATIC TRYPSIN INHIBITOR – TRYPSIN COMPLEX AND ITS FREE COMPONENTS: STRUCTURE AND FUNCTION RELATIONSHIP IN SERINE PROTEASE INHIBITION AND CATALYSIS (1976) (16)
- Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution. (1999) (16)
- The X-ray crystal structure of thrombin in complex with N alpha-2-naphthylsulfonyl-L-3-amidino-phenylalanyl-4-methylpiperidide: the beneficial effect of filling out an empty cavity. (1995) (15)
- Flexibility Analysis and Structure Comparison of Two Crystal Forms of Calcium-Free Human m-Calpain (2002) (14)
- The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. I. Crystallization, data collection and application of patterson search technique. (1975) (14)
- (R)-3-Amidinophenylalanine-Derived Inhibitors of Factor Xa with a Novel Active-Site Binding Mode (2002) (14)
- The single calcium-binding site of crystallin bovin beta-trypsin. (1975) (13)
- Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP. (2004) (13)
- Inhibition of trypsin by carbobenzyloxylysyl chloromethyl ketone: 13C NMR and x-ray diffraction analyses of the enzyme-inhibitor complex (1986) (13)
- Thermal transitions of Proteus mirabilis flagellin as studied by circular dichroism and adiabatic differential calorimetry (1973) (13)
- X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition. (2006) (13)
- LASER DIFFRACTION OF ORIENTED FIBRINOGEN MOLECULES * (1983) (12)
- Inflammation: the protein C pathway (1997) (12)
- The NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist? (2005) (12)
- Cyanogen bromide cleavage of Proteus mirabilis flagellin. Maleylation of cyanogen bromide peptides. (1972) (12)
- Structure and function of lysosomal cysteine proteinases and their protein inhibitors. (1985) (12)
- Interactions of thrombin with benzamidine-based inhibitors. (1992) (11)
- Role of tachylectins in host defense of the Japanese horseshoe crab Tachypleus tridentatus. (2001) (11)
- Bis-substituted malonic acid hydroxamate derivatives as inhibitors of human neutrophil collagenase (MMP8). (1998) (11)
- Correlation of Amino Acid Sequence with Inhibitor Activity and Specificity of Protein Inhibitors of Serine Proteinases (1981) (10)
- L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin. (2000) (10)
- The crystal structure of adamalysin II, a zinc-endopeptidase from the snake venom of the eastern diamondback rattlesnake Crotalus adamanteus. (1994) (10)
- X‐ray studies on antibody fragments (1974) (9)
- X-ray crystallographic and biochemical characterization of single crystals formed by proteolytically modified human fibrinogen. (1986) (9)
- Crystallographic Evidence That the F2 Kringle Catalytic Domain Linker of Prothrombin Does Not Cover the Fibrinogen Recognition Exosite (*) (1996) (9)
- L-asparaginase A from Escherichia coli. The molecular weight of the subunit and the demonstration of an intramolecular disulfide bridge. (1971) (9)
- Structure and specificity in coagulation and its inhibition. (1995) (9)
- Electrostatic properties of thrombin: importance for structural stabilization and ligand binding. (1993) (9)
- Electrostatic interactions in proteins: Calculations of the electrostatic term of free energy and the electrostatic potential field (1989) (9)
- Cloning, purification, crystallization and preliminary X-ray diffraction analysis of the antistasin-type inhibitor ghilanten (domain I) from Haementeria ghilianii in complex with porcine beta-trypsin. (2001) (8)
- Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10 (2016) (8)
- Cutting at the right place--the importance of selective limited proteolysis in the activation of proproteinase E. (1998) (8)
- ZZE -Configuration of Chromophore β-153 in C-Phycocyanin from Mastigocladus laminosus (1987) (8)
- Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin (2018) (7)
- Urethanyl-3-Amidinophenylalanine Derivatives as Inhibitors of Factor Xa. X-Ray Crystal Structure of a Trypsin/Inhibitor Complex and Modeling Studies (2000) (7)
- Crystallization and preliminary X‐ray diffraction analysis of gingipain R2 from Porphyromonas gingivalis in complex with H‐D‐Phe‐Phe‐Arg‐chloromethylketone (1998) (6)
- Bivalent inhibition of human beta-tryptase. (2001) (6)
- Crystallization of chicken egg white cystatin, a low molecular weight protein inhibitor of cysteine proteinases, and preliminary X-ray diffraction data. (1985) (6)
- The X-ray structures of porcine pancreatic kallikrein and of its complex with bovine pancreatic trypsin inhibitor. (1983) (6)
- Mutations of the PC2 Substrate Binding Pocket Alter Enzyme Specificity* (2005) (6)
- Sequence and structure similarities of cathepsin B from the parasite Schistosoma mansoni and human liver (1994) (6)
- Crystals of the NC1 domain of human type IV collagen. (1990) (6)
- Inhibition of Matrix Metalloproteinases in Rheumatoid Arthritis and the Crystallographic Binding Mode of a Peptide Inhibitor (1994) (6)
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- Pore-forming scissors? A first structural glimpse of gamma-secretase. (2006) (5)
- COLLAGENASE-3 (MMP-13) C-TERMINAL HEMOPEXIN-LIKE DOMAIN (1996) (5)
- THE CRYSTAL STRUCTURE OF CALCIUM-FREE HUMAN M-CALPAIN (2000) (5)
- Crystal Structures, Spectroscopic Features, and Catalytic Properties of Cobalt(II), Copper(II), Nickel(II), and Mercury(I1) Derivatives of the Zinc Endopeptidase Astacin (1994) (5)
- Effect of protein environment and the excitonic coupling on the excited-state properties of the bilinchromophores in C-Phycocyanin (1988) (5)
- Geometry of binding of the Nα‐tosylated piperidides of m‐amidino‐, p‐amidino‐ and p‐guanidino phenylalanine to thrombin and trypsin (2001) (4)
- The 1 . 8 Angstrom Crystal Structure of an MMP 8-Barbiturate Inhibitor Complex Reveals a Previously Unobserved Mechanism for Collagenase Substrate Recognition (2001) (4)
- Crystallization and preliminary X-ray analysis of recombinant full-length human m-calpain. (2000) (4)
- Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). (2008) (4)
- Serpin structures. (1993) (4)
- Crystallization and preliminary x-ray diffraction data of the cryptomonad biliprotein phycocyanin-645 from a Chroomonas spec. (1984) (4)
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- CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN (1996) (3)
- Crystal Structure of the Antihaemophilic Clotting Factor IXa (1996) (2)
- Fluorescence Behaviour of Crystallized C-Phycocyanin (Trimer) from Mastigocladus laminosus (1985) (2)
- YELLOW MEAL WORM ALPHA-AMYLASE IN COMPLEX WITH THE AMARANTH ALPHA-AMYLASE INHIBITOR (2000) (2)
- Crystal structure of uninhibited factor VIIa (2002) (2)
- X-ray crystal structures of thrombin in complex with D-Phe-Pro-Arg and with small benzamidine- and arginine-based "non-peptidic" inhibitors. (1993) (2)
- Structure of the ternary microplasmin-staphylokinase-microplasmin complex: a proteinase-cofactor-substrate complex in action (1999) (2)
- Synthesis of disulfide-bridged heterotrimeric collagen peptides. Conformational properties and digestion by matrix metalloproteinases (1999) (1)
- CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX (1999) (1)
- Function and Structure of Human Leucocyte Collagenase (1995) (1)
- COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) (1996) (1)
- Structural Aspects of Kallikrein-related Peptidases (2012) (1)
- REFINED X-RAY CRYSTAL STRUCTURES OF THE REACTIVE SITE MODIFIED OVOMUCOID INHIBITOR THIRD DOMAINS FROM SILVER PHEASANT (OMSVP3(ASTERISK)) AND FROM JAPANESE QUAIL (OMJPQ3(ASTERISK)) (1993) (1)
- Structural Basis for Possible Calcium-Induced Activation Mechanisms of Calpains (2001) (1)
- The Specific Interaction of Human Leukocyte Elastase with Various Protein Inhibitors (1988) (1)
- Size and shape of the fibrinogen molecule: crystalline forms of native and modified human fibrinogen (1986) (1)
- 2 The Refined X-Ray Crystal Structures of Human and Rat Liver Cathepsin B (1994) (1)
- Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Ala-Phe-cho (2002) (1)
- CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V (1999) (1)
- Complex structure of human thrombin with N-methyl-arginine inhibitor (2002) (1)
- PARACRYSTALLINE STRUCTURE OF NATIVE HUMAN FIBRINOGEN (1982) (1)
- Human b-tryptase isa ring-like tetramerwithactive sites facingacentral pore (1)
- Calorimetric studies on the in vitro polymerization of Pr. mirabilis flagellin. (1974) (1)
- Crystal structure of human carboxypeptidase M (2004) (1)
- Correlation between structure and enzymatic digestion in fibrinogen. (1980) (1)
- [Concentrically layered microconcrements in the renal medulla of nephrolithiasis patients. A contribution to the renal stone pathogenesis (author's transl)]. (1982) (1)
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- Crystallization and preliminary X‐ray diffraction analysis of proline iminopeptidase from Xanthomonas campestris pv. citri (1997) (1)
- Polymerization behaviour of carboxypeptidase B treated Proteus mirabilis flagellin. (1970) (1)
- Crystallization and preliminary X‐ray diffraction data of proteinase II from Crotalus adamanteus (Eastern Diamond Rattlesnake) (1983) (1)
- Calorimetric studies on thein vitro polymerization ofPr. mirabilis flagellin (1974) (1)
- Corrigendum to "Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity" (Journal of Molecular Biology, vol 371, pg 989, 2007) (2009) (1)
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- Table of Contents (1996) (0)
- COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE (1998) (0)
- d-to-tail cyclization of unprotected linear peptides with the KAHA ligation † (2015) (0)
- CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: DIMERIC CRYSTAL FORM (1999) (0)
- Factor XA in complex with (R)-2-(1-ADAMANTYLCARBAMOYLAMINO)-3-(3-CARBAMIDOYL-PHENYL)-N-PHENETHYL-PROPIONIC ACID AMIDE (2010) (0)
- Structures of Matrix Metalloproteinase - 9 in Complex with Pharmacological Inhibitors (2005) (0)
- CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE) (1999) (0)
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- High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone (2008) (0)
- A withproproteinase Eand chymotrypsinogen C (1995) (0)
- STRUCTURE OF SERINE PROTEINASE (1997) (0)
- Crystalline, in the asymmetric unit at least one involved in catalysis (Sub) -Domaine a human m-calpain, exhibiting polypeptide, methods for identifying compounds by using the same, processes for the crystallization and method for displaying a 3-dimensional structure of this peptide (1999) (0)
- CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE) (1999) (0)
- Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) (2003) (0)
- CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2) (2000) (0)
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- TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB) (1999) (0)
- Staphylocoagulase-Prethrombin-2 complex (2003) (0)
- Table of Contents (1996) (0)
- X-ray structure of human proMMP-1: New insights into collagenase action (2004) (0)
- Porcine dipeptidyl peptidase IV (CD26) in complex with 4-(2-Aminoethyl)-benzene sulphonyl fluoride (AEBSF) (2006) (0)
- Human alpha1-tryptase (2003) (0)
- 3-Dimensional structures of proteinases and inhibitors (1994) (0)
- X-ray structure of clotting factor IXa: Active site and module structure related to Xase activity and hemophilia B (x-ray (2005) (0)
- CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN (2003) (0)
- Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin (2018) (0)
- COMPLEX OF BENZAMIDINE WITH THE CATALYTIC DOMAIN OF HUMAN TWO CHAIN TISSUE PLASMINOGEN ACTIVATOR [(TC)-T-PA] (1997) (0)
- Crystal structure of human procaspase-7 (2002) (0)
- Crystal Structure of the Caspase-7 / XIAP-BIR2 Complex (2002) (0)
- AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE (1999) (0)
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- Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolysin (kscp) (2002) (0)
- Crystal structure of human promeprin beta (2012) (0)
- ACTIVATION, ACTION AND INHIBITION OF TRYPSIN AS DEDUCED FROM THE THREEDIMENSIONAL STRUCTURES OF TRYPSINOGEN, TRYPSIN AND THEIR COMPLEXES WITH THE BASIC PANCREATIC TRYPSIN INHIBITOR (1978) (0)
- Staphylocoagulase-Thrombin Complex (2003) (0)
- CRYSTALLOGRAPHY OF BIOLOGICAL MACROMOLECULES (2005) (0)
- High resolution crystal structure of a thermostable serine-carboxyl type proteinase, kumamolisin (kscp) (2002) (0)
- 156 Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single chain human tPA and vampire bat plasminogen activator (1997) (0)
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- Three-dimensional Structure of Human Tissue Inhibitor of Metalloproteinases-2 at 2 . 1 AÊ Resolution (1998) (0)
- Structure of astacin with a hydroxamic acid inhibitor (2000) (0)
- Table of Contents (1995) (0)
- X-Ray Structure of the Light-Harvesting Biliprotein C-Phycocyanin from M. laminosus (1987) (0)
- UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN INHIBITOR COMPLEX (2000) (0)
- Crystal structure of the thrombin-thrombomodulin complex (2000) (0)
- The thermostable serine-carboxyl type proteinase, kumamolisin (KSCP) - complex with Ac-Ile-Pro-Phe-cho (2002) (0)
- High Resolution Crystal Structure of Mutant W129A of Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP) (2004) (0)
- THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS (1998) (0)
- Crystal structure of pepV (2002) (0)
- Crystal structure of isoaspartyl dipeptidase from E. coli (0)
- Heterotrimeric collagen peptides as substrates of metalloproteinases (2002) (0)
- MMP-9 active site mutant with trifluoromethyl hydroxamate inhibitor (2007) (0)
- Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone (2008) (0)
- Factor Xa in complex with (R)-2-(3-adamantan-1-yl-ureido)-3-(3-carbamimidoyl-phenyl)-N-phenethyl-propionamide (2003) (0)
- Kallikrein-related peptidase 8 calcium complex (2018) (0)
- Specifity for Plasminogen Activator Inhibitor-1 (1999) (0)
- STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (1997) (0)
- Kallikrein-related peptidase 8 leupeptin inhibitor complex (2018) (0)
- HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE (1999) (0)
- COMPLEX OF 3-MERCAPTO-2-BENZYLPROPANOYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) (1996) (0)
- Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro) (2006) (0)
- Multiple Conformations of Cystatin, Mung Bean Inhibitor, and Serpins (1994) (0)
- Table of Contents (1994) (0)
- PORCINE FACTOR IXA (1996) (0)
- Table of Contents (1996) (0)
- CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE (1999) (0)
- MMP-9 active site mutant with iodine-labeled carboxylate inhibitor (2007) (0)
- PROCARBOXYPEPTIDASE TERNARY COMPLEX (1997) (0)
- THE DIMER INTERFACE OF THE MT1-MMP HEMOPEXIN DOMAIN: CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONS (2010) (0)
- MMP-9 active site mutant with difluoro butanoic acid inhibitor (2007) (0)
- CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE) (1999) (0)
- A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation (2005) (0)
- High-resolution crystal structure of C-Phycocyanin and polarized optical spectra of single crystals (1988) (0)
- Kallikrein-related peptidase 10 complex with Zn2+ (2016) (0)
- Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-Gly-L-Pro-L-Ile (tBu-GPI) (2006) (0)
- Crystal structure of MTSP1 (matriptase) (2002) (0)
- Staphylocoagulase bound to bovine thrombin (2005) (0)
- Isoaspartyl Dipeptidase with bound inhibitor (2004) (0)
- Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution (2001) (0)
- Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin (2006) (0)
- Nonbasic Thrombin Inhibitor Complex (2005) (0)
- Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera (2002) (0)
- 153 Catalytic domain of tissue-type plasminogen activator: The functional role of the surface-located loops and the identification of a hydrophobic exosite that modulates specificity for plasminogen (1997) (0)
- Table of Contents (1990) (0)
- Crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV: Stabilization via a novel type of covalent Met-Lys cross-link (2002) (0)
- Crystal structure of Isoaspartyl Dipeptidase (2004) (0)
- Plasminogen activator (TSV-PA) from snake venom (1999) (0)
- Table of Contents (1988) (0)
- Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition (2001) (0)
- STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR (2001) (0)
- Robert Huber--a life devoted to protein structures and functions. (1997) (0)
- Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor (2003) (0)
- bilities of peptide-based [ 1 ] rotaxanes : molecular grafting onto lasso peptide sca ff olds † (2017) (0)
- COMPLEX OF BB94 WITH THE CATALYTIC DOMAIN OF MATRIX METALLOPROTEINASE-8 (1996) (0)
- C-TERMINAL DOMAIN (HAEMOPEXIN-LIKE DOMAIN) OF HUMAN MATRIX METALLOPROTEINASE-2 (1996) (0)
- The Bowman-Birk type inhibitor from mung bean in ternary complex with porcine trypsin (2010) (0)
- JAPANESE HORSESHOE CRAB COAGULOGEN (1997) (0)
- 157 The “activation domain”: A highly cooperative entity within the catalytic domain of serine proteinases (1997) (0)
- Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper (2008) (0)
- Porcine dipeptidyl peptidase IV (CD26) in complex with 7-Benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-purine-2,6-dione (BDPX) (2006) (0)
- Table of Contents (1995) (0)
- Human Kallikrein 4 complex with cobalt and p-aminobenzamidine (2006) (0)
- TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C (1997) (0)
- NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI) (2000) (0)
- COMPLEX OF BDELLASTASIN WITH PORCINE TRYPSIN (2000) (0)
- Hemopexin-like domain of matrix metalloproteinase 14 (2009) (0)
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- Crystal structure of MT1-MMP hemopexin domain: identification of the dimer interface (2010) (0)
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- Crystal structure of the MTSP1 (matriptase)-BPTI (aprotinin) complex (2002) (0)
- MMP-9 active site mutant with barbiturate inhibitor (2007) (0)
- CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: COMPLEX WITH PHENYLMERCURY (1999) (0)
- COMPLEX OF 1-HYDROXYLAMINE-2-ISOBUTYLMALONYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) (1996) (0)
- Cofactor-and substrate-assisted activation of factor VIIa (2002) (0)
- Table of Contents (1991) (0)
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