Andy Dray
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Andy Draybiology Degrees
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Philosophy Biology
Andy Dray's Degrees
- PhD Neuroscience University of California, Berkeley
- Doctorate Medicine Stanford University
Why Is Andy Dray Influential?
(Suggest an Edit or Addition)Andy Dray's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bradykinin and inflammatory pain (1993) (630)
- Inflammatory mediators of pain. (1995) (593)
- Proenkephalin A gene products activate a new family of sensory neuron–specific GPCRs (2002) (353)
- Evidence for the existence of a raphe projection to the substantia nigra in rat (1976) (285)
- The striatum and substantia nigra: A commentary on their relationships (1979) (279)
- Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters (1994) (276)
- Chemical activation of nociceptive peripheral neurones. (1991) (263)
- Substance P in the substantia nigra (1976) (229)
- Pharmacology of chronic pain. (1994) (224)
- Kinins and kinin receptors in the nervous system (1995) (223)
- Synaptic mechanisms in the substantia nigra (1976) (217)
- Antinociceptive activity of the bradykinin B1 and B2 receptor antagonists, des-Arg9, [Leu8]-BK and HOE 140, in two models of persistent hyperalgesia in the rat (1993) (214)
- The dorsal and medial raphe projections to the substantia nigra in the rat: Electrophysiological, biochemical and behavioural observations (1978) (211)
- An in vitro study of the properties of single vagal afferents innervating guinea‐pig airways. (1993) (190)
- Caudate stimulation and substantia nigra activity in the rat. (1976) (178)
- The physiology and pharmacology of mammalian basal ganglia (1980) (169)
- Ruthenium red blocks the capsaicin-induced increase in intracellular calcium and activation of membrane currents in sensory neurones as well as the activation of peripheral nociceptors in vitro (1990) (168)
- Antagonism of 5‐hydroxytryptamine by LSD 25 in the central nervous system: a possible neuronal basis for the actions of LSD 25 (1970) (164)
- Neuropathic pain: emerging treatments. (2008) (159)
- Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro (1994) (157)
- Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin‐induced antinociception (1991) (156)
- Kinins and their receptors in hyperalgesia. (1997) (137)
- Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway C-fibres and vagus nerve from the guinea-pig (1995) (131)
- Arthritis and pain. Future targets to control osteoarthritis pain (2007) (127)
- D-α-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones (1977) (125)
- Knockdown of spinal metabotropic glutamate receptor 1 (mGluR1) alleviates pain and restores opioid efficacy after nerve injury in rats (2001) (123)
- Inhibition of urinary bladder contractions by a spinal action of morphine and other opioids. (1984) (115)
- Mechanism of action of capsaicin-like molecules on sensory neurons. (1992) (113)
- Bradykinin‐induced activation of nociceptors: receptor and mechanistic studies on the neonatal rat spinal cord‐tail preparation in vitro (1992) (111)
- Neuropharmacological mechanisms of capsaicin and related substances. (1992) (109)
- The role of neurokinin and N-methyl-d-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro (1993) (108)
- REVERSAL OF THE ACTION OF AMINO ACID ANTAGONISTS BY BARBITURATES AND OTHER HYPNOTIC DRUGS (1978) (100)
- Effects of enkephalin and morphine on Renshaw cells in feline spinal cord (1976) (100)
- Sensitization of peripheral afferent fibres in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins (1993) (99)
- Ions in the fire: recent ion-channel research and approaches to pain therapy. (1999) (99)
- New pharmacological strategies for pain relief. (1996) (97)
- Inflammation and hyperalgesia: highlighting the team effort. (1993) (96)
- Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro (1991) (92)
- In vivo antinociceptive activity of anti‐rat mGluR1 and mGluR5 antibodies in rats (1998) (92)
- Bradykinin-induced stimulation of afferent fibres is mediated through protein kinase C (1988) (92)
- Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiation (1994) (91)
- Serotonin in the basal ganglia: functions and interactions with other neuronal pathways. (1981) (86)
- MORPHINE AND NEUROTRANSMITTER SUBSTANCES: MICROIONTOPHORETIC STUDY IN THE RAT BRAIN STEM (1974) (83)
- Benzodiazepines: GABA and glycine receptors on single neurons in the rat medulla (1976) (77)
- Nerve growth factor induces mechanical allodynia associated with novel A fibre-evoked spinal reflex activity and enhanced neurokinin-1 receptor activation in the rat (1995) (74)
- PHARMACOLOGICAL AND ELECTROPHYSIOLOGICAL STUDIES OF MORPHINE AND ENKEPHALIN ON RAT SUPRASPINAL NEURONES AND CAT SPINAL NEURONES (1978) (71)
- Stimulation of guinea‐pig tracheal afferent fibres by non‐isosmotic and low‐chloride stimuli and the effect of frusemide. (1995) (70)
- Capsaicin desensitization of peripheral nociceptive fibres does not impair sensitivity to other noxious stimuli (1989) (68)
- D-α-Aminoadipate, α,ε-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synaptic excitation of mammalian spinal neurones in vivo (1978) (67)
- Depression of synaptic excitation and of amino acid induced excitatory responses of spinal neurones by D-alpha-aminoadipate, alpha,epsilon-diaminopimelic acid and HA-966. (1977) (67)
- Modification of the responses of brain stem neurones to transmitter substances by anaesthetic agents (1973) (66)
- Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region". (1993) (63)
- Opioid receptor subtypes involved in the central inhibition of urinary bladder motility. (1984) (61)
- Activation of a bradykinin receptor in peripheral nerve and spinal cord in the neonatal rat in vitro (1988) (60)
- Regulation of nigro-striatal dopaminergic neurotransmission in the rat (1977) (59)
- Actions of capsaicin on peripheral nociceptors of the neonatal rat spinal cord‐tail in vitro: dependence of extracellular ions and independence of second messengers (1990) (59)
- Morphine and the centrally-mediated inhibition of urinary bladder motility in the rat (1984) (58)
- Capsaicin-induced activation of fine afferent fibres from rat skin in vitro (1993) (56)
- Barbiturate reversal of amino acid antagonism produced by convulsant agents (1976) (55)
- METABOTROPIC GLUTAMATE RECEPTOR ACTIVATION CONTRIBUTES TO NOCICEPTIVE REFLEX ACTIVITY IN THE RAT SPINAL CORD IN VITRO (1996) (52)
- 5-Hydroxytryptamine-induced sensitization and activation of peripheral fibres in the neonatal rat are mediated via different 5-hydroxytryptamine-receptors (1992) (52)
- Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain (2003) (52)
- Pro-nociceptive effects of neuromedin u in rat (2003) (52)
- Rotational behaviour following inhibition of GABA metabolism unilaterally in the rat substantia nigra (1975) (50)
- Contribution of NK1 and NK2 receptor activation to high threshold afferent fibre evoked ventral root responses in the rat spinal cord in vitro (1993) (48)
- Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro (1992) (47)
- Effects of substance P on adult rat sensory ganglion neurones in vitro (1982) (46)
- Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: Morphology and distribution (1994) (46)
- Substance P and opiate receptors (1977) (45)
- A pro-nociceptive role of neuromedin U in adult mice (2003) (43)
- Central δ‐opioid receptor interactions and the inhibition of reflex urinary bladder contractions in the rat (1985) (41)
- Cobalt uptake enables identification of capsaicin- and bradykinin-sensitive subpopulations of rat dorsal root ganglion cellsin vitro (1993) (41)
- NE-19550 and NE-21610, antinociceptive capsaicin analogues: studies on nociceptive fibres of the neonatal rat tail in vitro. (1990) (41)
- Leukemia inhibitory factor induces mechanical allodynia but not thermal hyperalgesia in the juvenile rat (1996) (40)
- Systemic capsaicin and olvanil reduce the acute algogenic and the late inflammatory phase following formalin injection into rodent paw (1991) (39)
- Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation (2002) (39)
- A spinal mechanism of action is involved in the antinociception produced by the capsaicin analogue NE 19550 (olvanil) (1990) (39)
- Kinins and Pain (1997) (36)
- Bromocriptine and dopamine‐receptor stimulation (1976) (36)
- Hyperalgesia in rats following intracerebroventricular administration of endotoxin: effect of bradykinin B1 and B2 receptor antagonist treatment (1996) (35)
- Epidural opiates and urinary retention: new models provide new insights. (1988) (32)
- Selective δ-opioid receptor antagonism by ICI 174,864 in the central nervous system (1984) (32)
- Depression and facilitation of synaptic responses in cat dorsal horn by substance P administered into substantia gelatinosa. (1980) (31)
- Spinal opioid receptors and inhibition of urinary bladder motility in vivo (1984) (31)
- Desensitization and capsaicin-induced release of substance P-like immunoreactivity from guinea-pig ureter in vitro (1989) (31)
- Tachykinin induced regulation of excitatory amino acid responses in the rat spinal cord in vitro (1994) (30)
- Priming enhances endotoxin-induced thermal hyperalgesia and mechanical allodynia in rats (1998) (30)
- Resiniferatoxin, a potent capsaicin‐like stimulator of peripheral nociceptors in the neonatal rat tail in vitro (1990) (29)
- Neuropeptide FF attenuates allodynia in models of chronic inflammation and neuropathy following intrathecal or intracerebroventricular administration. (2000) (29)
- Osteoarthritic pain: a review of current, theoretical and emerging therapeutics (2008) (28)
- Activity of deep dorsal horn neurons in the anaesthetized rat during hyperalgesia of the hindpaw induced by ultraviolet irradiation (1993) (28)
- Novel G protein-coupled receptors as pain targets. (2004) (28)
- Opioids and central inhibition of urinary bladder motility. (1984) (27)
- Actions of capsaicin on mouse dorsal root ganglion cells in vitro (1993) (26)
- Supraspinal and spinal mechanisms in morphine-induced inhibition of reflex urinary bladder contractions in the rat (1987) (25)
- Peripheral Mediators of Pain (1997) (25)
- Antinociception produced by capsaicin: spinal or peripheral mechanism? (1990) (24)
- The rat urinary bladder. A novel preparation for the investigation of central opioid activity in vivo. (1985) (23)
- Opioid inhibition of reflex urinary bladder contractions: dissociation of supraspinal and spinal mechanisms (1985) (23)
- The proenkephalin A fragment, peptide E: central processing and CNS activity in vivo. (1985) (22)
- Short‐latency excitation of brain stem neurones in the rat by acetylcholine (1972) (22)
- OBSERVATIONS ON THE PHARMACOLOGY OF CHOLINOCEPTIVE NEURONES IN THE RAT BRAIN STEM (1976) (21)
- New horizons in pharmacologic treatment for rheumatic disease pain. (2008) (21)
- The how and why of chronic pain states and the what of new analgesia therapies (1998) (21)
- Stimulation of afferent fibres of the guinea‐pig ureter evokes potentials in inferior mesenteric ganglion neurones. (1988) (20)
- Enhanced thermal antinociceptive potency and anti-allodynic effects of morphine following spinal administration of endotoxin (2003) (20)
- Comparison of the Sensory Threshold in Healthy Human Volunteers with the Sensory Nerve Response of the Rat In Vitro Hindlimb Skin and Saphenous Nerve Preparation on Cutaneous Electrical Stimulation (1995) (19)
- Osteoarthritic pain: a review of current, theoretical and emerging therapeutics. (2008) (19)
- Comparison of bicuculline methochloride with bicuculline and picrotoxin as antagonists of amino acid and monoamine depression of neurones in the rat brainstem (1975) (19)
- No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro (1995) (18)
- Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat. (2001) (18)
- Tetramethylenedisulphotetramine and amino acid inhibition in the rat brain (1975) (18)
- LSD's effect on neuron populations in visual cortex gauged by transient responses of extracellular potassium evoked by optical stimuli (1979) (18)
- Changes in amino acid sensitivity during polypeptide ‘desensitisation’ (1976) (18)
- Regulation of bradykinin sensitivity in peripheral sensory fibres of the neonatal rat by nitric oxide and cyclic GMP (1994) (17)
- Pharmacological characterization of the effects of 5-hydroxytryptamine and different prostaglandins on peripheral sensory neuronsin vitro (2005) (16)
- Evidence that naloxonazine produces prolonged antagonism of central delta opioid receptor activity in vivo (1984) (16)
- Development of hyperthermia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists (1996) (16)
- Chapter 6 Neurogenic mechanisms and neuropeptides in chronic pain (1996) (15)
- Antagonism by LSD to effects of 5-HT on single neurones. (1969) (15)
- Novel pharmacological strategies for analgesia. (1996) (15)
- Immunochemical detection of photoaffinity‐labelled capsaicin‐binding proteins from sensory neurons (1990) (15)
- The selective NK-2 receptor antagonist MEN 10,376 inhibits synaptic excitation of dorsal horn neurons evoked by C-fibre activation in the in vitro rat spinal cord (1992) (14)
- Effects of α-flupenthixol on dopamine and 5-hydroxytryptamine responses of substantia nigra neurones (1976) (14)
- Novel molecular targets in pain control (2003) (14)
- Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists. (1996) (13)
- Neurogenic mechanisms and neuropeptides in chronic pain. (1996) (13)
- Proenkephalin A fragments exhibit spinal and supraspinal opioid activity in vivo. (1985) (13)
- The involvement of afferent nerve terminals in the stimulation of ion transport by bradykinin in rat isolated colon (1988) (13)
- Vascular effects of substance P change synaptic responsiveness of cat dorsal horn neurons. (1980) (13)
- Bradykinin depolarises the rat isolated superior cervical ganglion via B2 receptor activation (1995) (13)
- THE EFFECTS OF MICROIONTOPHORETICALLY APPLIED MORPHINE AND TRANSMITTER SUBSTANCES IN RATS DURING CHRONIC TREATMENT AND AFTER WITHDRAWAL FROM MORPHINE (1974) (13)
- Motilin acts within the CNS to inhibit urinary bladder contractions. (1984) (12)
- Future pharmacologic management of neuropathic pain. (2004) (12)
- Actions and interactions of microiontophoretically applied morphine with transmitter substances on brain stem neurones. (1973) (11)
- The effects of LSD and some analogues on the responses of single cortical neurons of the cat to optical stimulation (1980) (11)
- Opioid receptor ligands in the neonatal rat spinal cord: binding and in vitro depression of the nociceptive responses (1990) (11)
- Non-cholinergic synaptic potentials mediated by lumbar colonic nerve in the guinea-pig inferior mesenteric ganglion in vitro (1988) (11)
- Naloxonazine and opioid-induced inhibition of reflex urinary bladder contractions (1987) (11)
- Effects of caudate stimulation and micro-iontophoretically applied substances on neurones in the rat substantia nigra. (1975) (10)
- Meptazinol: Unusual in vivo opioid receptor activity at supraspinal and spinal sites (1986) (10)
- Mu and delta opioid ligands inhibit reflex contractions of the urinary bladder in the rat by different central mechanisms (1987) (10)
- Neuropeptide Y depresses reflex urinary bladder contractions in rats and modifies central activity of opioid agonists (1986) (10)
- The effects of different anaesthetics on responses of brain stem neurones to iontophoretically applied transmitter substances. (1972) (9)
- Prolonged invivo antagonism of central Mu- and delta-opioid receptor activity by β-funaltrexamine (1985) (9)
- Endorphins and the central inhibition of urinary bladder motility (1984) (9)
- CHEMOSENSITIVITY OF CULTURED DORSAL ROOT GANGLIA CELLS (1996) (9)
- Iontophoresis of LSD: effects on responses of single cortical neurones to visual stimulation (1979) (8)
- Bradykinin activates peripheral capsaicin-sensitive fibres via a second messenger system (1988) (8)
- The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro (1992) (8)
- Chapter 14 Peptidergic afferents: physiological aspects (1995) (7)
- Proceedings: Comparison of circling behaviour following unilateral inhibition of GABA-transaminase or discrete electroyltic lesioning in the rat substantia nigra. (1975) (7)
- Actions of neuropeptide K and calcitonin gene-related peptide on inferior mesenteric ganglion cells — Tachykinin interactions with non-cholinergic potentials evoked by ureteric nerve stimulation (1988) (7)
- Selective depression of nociceptive responses of dorsal horn neurones by SNC 80 in a perfused hindquarter preparation of adult mouse (2001) (6)
- Effects of lysergic acid derivatives on 5-hydroxytryptamine excitation of brain stem neurones. (1970) (6)
- The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo (1985) (6)
- 5.53 – Pharmacological Modulation of Pain (2008) (6)
- The effects of ethanolamine-O-sulphate injection into the rat substantia nigra: electrophysiological studies (1978) (5)
- Projections from nucleus accumbens to globus pallidus and substantia nigra in the rat (1978) (5)
- Antinociception induced by the capsaicin analogue, olvanil : peripheral and central sites of action studied in vivo in adult rats and in vitro using neonatal rat (1990) (5)
- Desensitization of bradykinin-induced activation of peripheral nociceptors. (1992) (5)
- Metabotropic glutamate receptor activation contributes to the nociceptive reflex response in the neonatal rat spinal cord in vitro (1996) (4)
- Studies of the effects of morphine and related substances on single neuronesin the brainstem (1976) (4)
- Peptidergic afferents: physiological aspects. (1995) (3)
- Possible branching of myelinated primary afferent fibres in the dorsal root of the rat (1995) (3)
- Selective delta-opioid receptor antagonism by ICI 174,864 in the central nervous system. (1984) (3)
- Bradykinin and capsaicin evoked activation of single vagal C-fibres in the guinea-pig airways in vitro (1993) (3)
- Interactions of Central Depressants with Amino Acids and Their Antagonists (1978) (3)
- D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo. (1978) (3)
- Centrally administered ß;-endorphin produces prolonged changes in δ-opioid ligand activity in vivo (1986) (2)
- The pro-enkephalin A derivative, peptide E, is centrally processed to active fragments. (1984) (2)
- GAP-43 immunoreactivity is enhanced after UV irradiation in the peripheral nervous system of the rat (1997) (2)
- Proceedings: Evaluation of iontophoretic N-methylbicuculline and other inhibitory amino-acid antagonists in rat brain stem. (1974) (2)
- Extracellular recording in rat substantia nigra. (1975) (2)
- Characterization of capsaicin-induced release of substance P like immunoreactivity (SPLI) from guinea pig ureter in vitro (1988) (1)
- Centrally administered beta-endorphin produces prolonged changes in delta-opioid ligand activity in vivo. (1986) (1)
- 1226 – SUBSTANCE P: POSSIBLE ROLE IN SPINAL PATHWAYS SUBSERVING PAIN (1978) (1)
- Inflammation-induced increase in NK1 receptor mediated responses in the neonatal rat spinal cord in vitro (1993) (1)
- Sensitization of nociceptors to bradykinin produced by inflammatory meditors (1990) (1)
- Central 6-opioid receptor interactions andtheinhibition ofreflex urinary bladder contractions intherat (1985) (1)
- Hyperexcitabilty in the Spinal Dorsal Horn: Cooperation of Neuropeptides and Excitatory Amino Acids (1994) (1)
- Effects of D-α-aminoadipate on physiologically evoked responses of cat dorsal horn neurones (1979) (1)
- Methiothepin and a 5-HT pathway to rat substantia nigra (1977) (1)
- Actions of enkephalin and morphine on spinal cord and brain stem neurones [proceedings]. (1976) (1)
- Prolonged in vivo antagonism of central mu- and delta-opioid receptor activity by beta-funal trexamine. (1985) (1)
- Pentobarbitone enhancement of the inhibitory action of GABA (reply) (1977) (1)
- Pathophysiology and Future Pharmacotherapy of Chronic Pain (1995) (0)
- Noradrenaline artefacts. (1972) (0)
- Spinal and supra spinal actions of pro-enkephalin a fragments on gastro intestinal transit (GIT) and urinary bladder motility (UBM) (1984) (0)
- Influences of the Chemical Environment on Peripheral Afferent Neurons (1994) (0)
- The amidated proenkephalin A fragment metorphamide shows selective opioid activity in vivo (1985) (0)
- Reply (1993) (0)
- BRADYKININ-INDUCED STIMULATION OF NOCICEPTORS IN THE NEONATAL RAT SPINAL CORD/TAIL IN VITRO : CONTRIBUTION OF NITRIC OXIDE ? (1991) (0)
- The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro (1992) (0)
- Urinary Retention following Spinal Opiates (1988) (0)
- Local effector function of ureteric afferents (1988) (0)
- Potentiation of nociceptive activity in the neo-natal rat spinal cord by peripheral prostaglandins (1987) (0)
- BradykMn and inflammatory pain (1993) (0)
- Proceedings: A raphe-substantia nigra projection in the rat. (1976) (0)
- Centrally-administered motilin inhibits the micturition reflex in rats (1984) (0)
- Pain Processing in the Periphery Development of Analgesics (2003) (0)
- Effects of D-alpha-aminoadipate on physiologically evoked responses of cat dorsal horn neurones. (1979) (0)
- The effects of a NK1 receptor antagonist (RP67 580) on neurokinin receptors in the neonatal rat spinal cord (1994) (0)
- 'Recoil', 'Onview' and 'Safelink' (1996) (0)
- Option and vision (1996) (0)
- Pain mechanisms: Experimental and clinical relationships (2001) (0)
- DIVA (Digitally integrated video and audio) (2000) (0)
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