Armen H. Jr. Tashjian

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Armen H. Jr. Tashjian

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#34

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Biochemistry

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#535

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Philosophy
Biology

Armen H. Jr. Tashjian's Degrees

Doctorate Medicine Harvard University

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Armen H. Jr. Tashjian's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. (1968) (626)
C-cell hyperplasia preceding medullary thyroid carcinoma. (1973) (423)
Thyrotropin releasing hormone: direct evidence for stimulation of prolactin production by pituitary cells in culture. (1971) (401)
Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. (1975) (378)
Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria. (1985) (374)
EVIDENCE THAT THE BONE RESORPTION-STIMULATING FACTOR PRODUCED BY MOUSE FIBROSARCOMA CELLS IS PROSTAGLANDIN E2 (1972) (362)
The clinical outcome of prospective screening for multiple endocrine neoplasia type 2a. An 18-year experience. (1988) (311)
PRODUCTION OF BOTH PROLACTIN AND GROWTH HORMONE BY CLONAL STRAINS OF RAT PITUITARY TUMOR CELLS (1970) (303)
Early diagnosis of medullary carcinoma of the thyroid gland by means of calcitonin assay. (1971) (264)
Epidermal growth factor stimulates prostaglandin production and bone resorption in cultured mouse calvaria. (1978) (256)
Thyrotropin-releasing hormone regulates the number of its own receptors in the GH3 strain of pituitary cells in culture. (1975) (249)
Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. (1996) (238)
[46] Clonal strains of hormone-producing pituitary cells (1979) (232)
Tumor necrosis factor-alpha (cachectin) stimulates bone resorption in mouse calvaria via a prostaglandin-mediated mechanism. (1987) (227)
Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhibition of cell proliferation (1980) (203)
Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function. (1973) (200)
Establishment of Four Functional, Clonal Strains of Animal Cells in Culture (1966) (191)
Hypercalcemia and tumor-prostaglandins: the VX2 carcinoma model in the rabbit. (1975) (188)
Natural history of familial medullary thyroid carcinoma: effect of a program for early diagnosis. (1978) (185)
Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine. (1984) (182)
Platelet-derived growth factor stimulates bone resorption via a prostaglandin-mediated mechanism. (1982) (176)
Hydrocortisone inhibits prostaglandin production by mouse fibrosarcoma cells (1975) (168)
Studies in familial (medullary) thyroid carcinoma. (1972) (167)
Characterization of beta-adrenergic receptors on rat and human osteoblast-like cells and demonstration that beta-receptor agonists can stimulate bone resorption in organ culture. (1993) (165)
Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary cells in culture. (1973) (161)
The syndrome of excessive thyrocalcitonin produced by medullary carcinoma of the thyroid. (1968) (156)
Medullary carcinoma of the thyroid gland. Studies of thyrocalcitonin in plasma and tumor extracts. (1968) (155)
Prostaglandin production by mouse fibrosarcoma cells in culture: inhibition by indomethacin and aspirin. (1972) (154)
Inositol tetrakis- and pentakisphosphates in GH4 cells. (1985) (150)
Distribution of calcitonin-containing cells in the normal adult human thyroid gland: a correlation of morphology with peptide content. (1974) (149)
Teriparatide [Human PTH(1‐34)]: 2.5 Years of Experience on the Use and Safety of the Drug for the Treatment of Osteoporosis (2005) (145)
Thyrotropin-releasing hormone-induced spike and plateau in cytosolic free Ca2+ concentrations in pituitary cells. Relation to prolactin release. (1984) (143)
Direct modulation by estradiol of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTH-related protein. (1989) (143)
Distinct patterns of cytoplasmic protein phosphorylation related to regulation of synthesis and release of prolactin by GH cells. (1983) (140)
IMMUNOCHEMICAL IDENTIFICATION OF PARATHYROID HORMONE IN NON-PARATHYROID NEOPLASMS ASSOCIATED WITH HYPERCALCEMIA (1964) (139)
A possible role of cyclic AMP in mediating the effects of thyrotropin-releasing hormone on prolactin release and on prolactin and growth hormone synthesis in pituitary cells in culture. (1976) (139)
Calcitonin and carcinoembryonic antigen as tumor markers in medullary thyroid carcinoma. (1978) (136)
Commentary on Clinical Safety of Recombinant Human Parathyroid Hormone 1‐34 in the Treatment of Osteoporosis in Men and Postmenopausal Women (2002) (136)
CONTROL OF GROWTH HORMONE PRODUCTION BY A CLONAL STRAIN OF RAT PITUITARY CELLS (1969) (134)
Calcitonin binding sites in bone: relationships to biological response and "escape". (1978) (128)
Novel mechanism of intracellular calcium release in pituitary cells. (1991) (128)
Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells. (1981) (127)
Vasoactive intestinal peptide stimulates bone resorption via a cyclic adenosine 3',5'-monophosphate-dependent mechanism. (1983) (126)
Biological activities of prostaglandin analogues and metabolites on bone in organ culture (1977) (125)
Clinical characteristics distinguishing hereditary from sporadic medullary thyroid carcinoma. Treatment implications. (1980) (123)
NOVEL HYPOTHALAMIC ARACHIDONATE PRODUCTS STIMULATE SOMATOSTATIN RELEASE FROM THE MEDIAN EMINENCE1 (1983) (119)
ESTABLISHMENT OF A CLONAL STRAIN OF HEPATOMA CELLS WHICH SECRETE ALBUMIN (1969) (119)
Detection of medullary thyroid cancer by calcitonin assay in families. (1972) (116)
Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution. (2000) (109)
Human osteopetrosis: a histological, ultrastructural, and biochemical study. (1980) (104)
Effects of parathyroid hormone and calcitonin on osteoclast formation in vitro. (1980) (103)
The clinical and screening age-at-onset distribution for the MEN-2 syndrome. (1989) (101)
Prostaglandins, calcium metabolism and cancer. (1974) (101)
Three activators of protein kinase C, bryostatins, dioleins, and phorbol esters, show differing specificities of action on GH4 pituitary cells. (1986) (100)
Overexpression of protein kinase C epsilon is oncogenic in rat colonic epithelial cells. (1996) (100)
Receptor-binding affinities and biological activities of analogs of thyrotropin-releasing hormone in prolactin-producing pituitary cells in culture. (1974) (99)
Role of calcium in the thyrotropin-releasing hormone-stimulated release of prolactin from pituitary cells in culture. (1978) (99)
Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling. (1974) (97)
Successful treatment of hypercalcemia by indomethacin in mice bearing a prostaglandin-producing fibrosarcoma. (1973) (93)
RENAL ADENOCARCINOMA CONTAINING A PARATHYROID HORMONE-LIKE SUBSTANCE AND ASSOCIATED WITH MARKED HYPERCALCEMIA. (1964) (92)
Thyrotropin-releasing hormone induces redistribution of protein kinase C in GH4C1 rat pituitary cells. (1985) (91)
Human milk lipids. II. The influence of dietary carbohydrates and fat on the fatty acids of mature milk. A study in four ethnic groups. (1965) (90)
Tumor-promoting phorbol esters affect production of prolactin and growth hormone by rat pituitary cells. (1981) (87)
Stimulation of prostaglandin production in bone by phorbol diesters and melittin. (1978) (86)
Actions of growth factors on plasma calcium. Epidermal growth factor and human transforming growth factor-alpha cause elevation of plasma calcium in mice. (1986) (86)
Clonal strains of hormone-producing pituitary cells. (1979) (85)
Age-resolving Osteopetrosis: A Rat Model Implicating Microphthalmia and the Related Transcription Factor TFE3 (1998) (84)
Pseudohypoparathyroidism: assays of parathyroid hormone and thyrocalcitonin. (1966) (84)
Functional receptors for vasoactive intestinal peptide on human osteosarcoma cells. (1984) (82)
PKCδ acts as a growth and tumor suppressor in rat colonic epithelial cells (1999) (81)
Demonstration by immunoperoxidase staining of hyperplasia of parafollicular cells in the thyroid gland in hyperparathyroidism. (1973) (80)
Voltage-dependent calcium channels in pituitary cells in culture. II. Participation in thyrotropin-releasing hormone action on prolactin release. (1984) (80)
Human calcitonin. Immunologic assay, cytologic localization and studies on medullary thyroid carcinoma. (1974) (80)
Subunits of human chorionic gonadotropin: unbalanced synthesis and secretion by clonal cell strains derived from a bronchogenic carcinoma. (1973) (77)
Dual actions of phorbol esters on cytosolic free Ca2+ concentrations and reconstitution with ionomycin of acute thyrotropin-releasing hormone responses. (1985) (77)
Establishment of a calcitonin-producing rat medullary thyroid carcinoma cell line. II. Secretory studies of the tumor and cells in culture. (1980) (76)
Management of occult medullary thyroid carcinoma: evidenced only by serum calcitonin level elevations after apparently adequate neck operations. (1978) (76)
Intravenous infusion of prostaglandin E2 raises plasma calcium concentration in the rat. (1975) (76)
Protein kinase Cε is oncogenic in colon epithelial cells by interaction with the ras signal transduction pathway (1998) (75)
Receptor-mediated release of plasma membrane-associated calcium and stimulation of calcium uptake by thyrotropin-releasing hormone in pituitary cells in culture. (1981) (75)
Calmodulin is a selective mediator of Ca(2+)-induced Ca2+ release via the ryanodine receptor-like Ca2+ channel triggered by cyclic ADP-ribose. (1995) (75)
Measurement of cytosolic free Ca2+ concentrations in human and rat osteosarcoma cells: actions of bone resorption-stimulating hormones. (1986) (74)
ALKYLATION AND OXIDATION OF METHIONINE IN BOVINE PARATHYROID HORMONE: EFFECTS ON HORMONAL ACTIVITY AND ANTIGENICITY. (1964) (74)
Voltage-dependent calcium channels in pituitary cells in culture. I. Characterization by 45Ca2+ fluxes. (1984) (72)
Age-related probability of development of hereditary medullary thyroid carcinoma. (1982) (71)
C-cell hyperplasia and medullary thyroid carcinoma in the rat. An immunohistochemical and ultrastructural analysis. (1979) (71)
Role of prostaglandins in the production of hypercalcemia by tumors. (1978) (69)
Dual actions of 1,25-dihydroxycholecalciferol on intracellular Ca2+ in GH4C1 cells: evidence for effects on voltage-operated Ca2+ channels and Na+/Ca2+ exchange. (1989) (69)
Bone resorption in organ culture: inhibition by the divalent cation ionophores A23187 and X-537A. (1976) (68)
Human parathyroid hormone (PTH)-related protein and human PTH: comparative biological activities on human bone cells and bone resorption. (1988) (66)
Cyclooxygenase products of arachidonic acid metabolism by mouse bone in organ culture. (1980) (66)
Inositol 1-,4-,5-trisphosphate-dependent Ca2+ signaling by the recombinant human PTH/PTHrP receptor stably expressed in a human kidney cell line. (1996) (61)
Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors. (1993) (61)
Cushing's syndrome caused by ACTH- and calcitonin-secreting medullary carcinoma of the thyroid. (1970) (61)
Functional identification and quantitation of three intracellular calcium pools in GH4C1 cells: evidence that the caffeine-responsive pool is coupled to a thapsigargin-resistant, ATP-dependent process. (1993) (61)
Concentrations of calcitonin and catecholamines in pheochromocytomas, a mucosal neuroma and medullary thyroid carcinoma. (1973) (61)
Production of a low molecular weight eosinophil polymorphonuclear leukocyte chemotactic factor by anaplastic squamous cell carcinomas of human lung. (1978) (61)
Unusual sensitivity of cytosolic free Ca2+ to changes in extracellular Ca2+ in rat C-cells. (1986) (60)
Characterization of an early inhibitory effect of glucocorticoids on stimulated adrenocorticotropin and endorphin release from a clonal strain of mouse pituitary cells. (1982) (58)
Signaling by N- and C-terminal sequences of parathyroid hormone-related protein in hippocampal neurons. (1995) (57)
Epidermal growth factor and phorbol ester actions on human osteosarcoma cells. Characterization of response and nonresponsive cell lines. (1982) (57)
Modulation of somatostatin receptors by thyrotropin-releasing hormone in a clonal pituitary cell strain. (1980) (56)
Prostaglandins, Hypercalcemia and Cancer (1975) (56)
Growth in suspension culture of rat pituitary cells which produce growth hormone and prolactin. (1971) (56)
Regulation of prolactin mRNA by 1,25-dihydroxyvitamin D3 in GH4C1 cells. (1983) (55)
Serum histaminase and calcitonin levels in medullary carcinoma of the thyroid. (1972) (55)
Thyrotropin-releasing Hormone-induced Spike and Plateau in Cytosolic Free Ca2+ Concentrations in Pituitary Cells (1984) (54)
Effects of cations and colchicine on the release of prolactin and growth hormone by functional pituitary tumor cells in culture. (1973) (53)
Hydrocortisone increases the number of receptors for thyrotropin-releasing hormone on pituitary cells in culture. (1977) (53)
Stimulation by parathyroid hormone of 45Ca2+ uptake in osteoblast-like cells: possible involvement of alkaline phosphatase. (1990) (51)
Agonist-independent, muscle-type-specific signal transduction pathways in cat esophageal and lower esophageal sphincter circular smooth muscle. (1995) (51)
Natural history of the familial medullary thyroid carcinoma-pheochromocytoma syndrome and the identification of preneoplastic stages by screening studies: a five-year report. (1975) (51)
Modulation of peptide binding to specific receptors on rat pituitary cells by tumor-promoting phorbol esters: decreased binding of thyrotropin-releasing hormone and somatostatin as well as epidermal growth factor. (1982) (50)
The clinical course after definitive operation for medullary thyroid carcinoma. (1983) (50)
Transfer of Bilirubin Uridine Diphosphate-Glucuronyltransferase to Enzyme-Deficient Rats (1970) (50)
Immunoassay of thyrocalcitonin. I. The method and its serological specificity. (1969) (50)
Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin E2 in rabbits bearing the VX2 carcinoma: effects of hydrocortisone and indomethacin. (1977) (49)
Hypercalcemia in dogs with adenocarcinoma derived from apocrine glands of the anal sac. Biochemical and histomorphometric investigations. (1983) (48)
Establishment of a clonal strain of hepatoma cells which maintain in culture the five enzymes of the urea cycle (1974) (48)
Mechanism of spontaneous intracellular calcium fluctuations in single GH4C1 rat pituitary cells. (1993) (48)
Hypercalcemia and calcinosis in Florida horses: implication of the shrub, Cestrum diurnum, as the causative agent. (1975) (48)
The two-mutational-event theory in medullary thyroid cancer. (1979) (48)
Parathyroid hormone stimulates bone resorption via a Na–Ca exchange mechanism (1980) (48)
Molecular cloning of a complementary deoxyribonucleic acid encoding the thyrotropin-releasing hormone receptor and regulation of its messenger ribonucleic acid in rat GH cells. (1992) (47)
Complement biosynthesis in vitro by rat hepatoma cell strains. (1975) (47)
Molecular cloning of a complementary deoxyribonucleic acid encoding the thyrotropin-releasing hormone receptor and regulation of its messenger ribonucleic acid in rat GH cells. (1992) (46)
Comparison of Recombinant Human PTH(1–34) (LY333334) with a C‐Terminally Substituted Analog of Human PTH‐Related Protein(1–34) (RS‐66271): In Vitro Activity and In Vivo Pharmacological Effects in Rats (1999) (46)
Characterization of neurotensin production by a line of rat medullary thyroid carcinoma cells. (1980) (46)
Vitamin D stimulates prolactin synthesis by GH4C1 cells incubated in chemically defined medium. (1982) (45)
Thyrotropin-releasing hormone (TRH) elevation of inositol trisphosphate and cytosolic free calcium is dependent on receptor number. Evidence for multiple rapid interactions between TRH and its receptor. (1986) (45)
Diacylglycerol increases cytosolic free Ca2+ concentration in rat pituitary cells. Relationship to thyrotropin-releasing hormone action. (1987) (45)
Surgical approach to early familial medullary carcinoma of the thyroid gland. (1972) (44)
Studies on the role of the liver in the metabolism of parathyroid hormone. I. Effects of partial hepatectomy and incubation of the hormone with tissue homogenates. (1972) (44)
Structure‐activity studies of the s‐echistatin inhibition of bone resorption (1994) (44)
Erratum: Teriparatide human PTH(1-34): 2.5 Years of experience on the use and safety of the drug for the treatment of osteoporosis (Journal of Bone and Mineral Research (March 2006) 21 (354-365)) (2006) (43)
Evidence for parathyroid hormone in nonparathyroid tumors associated with hypercalcemia. (1965) (42)
Modulation of recombinant human prostate-specific antigen: activation by Hofmeister salts and inhibition by azapeptides. Appendix: thermodynamic interpretation of the activation by concentrated salts. (2001) (41)
CHAPTER 6 – Cell Culture Studies of Thyrotropin-Releasing Hormone Action (1977) (41)
Effects of Ca ++ and Mg ++ on secretion and synthesis of growth hormone and prolactin by clonal strains of pituitary cell in culture. (1973) (41)
Mechanisms of desensitization to parathyroid hormone in human osteoblast-like SaOS-2 cells. (1992) (41)
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women. (1973) (40)
Hypercalcemia in dogs with lymphosarcoma. Biochemical, ultrastructural, and histomorphometric investigations. (1983) (40)
Neplanocin A. Actions on S-adenosylhomocysteine hydrolase and on hormone synthesis by GH4C1 cells. (1986) (40)
Thimerosal potentiates Ca2+ release mediated by both the inositol 1,4,5-trisphosphate and the ryanodine receptors in sea urchin eggs. Implications for mechanistic studies on Ca2+ signaling. (1994) (39)
Familial pseudohypoparathyroidism. Role of parathyroid hormone and thyrocalcitonin. (1968) (38)
Effects of hydrocortisone on the hypercalcemia and plasma levels of 13,14-dihydro-15-keto-prostaglandin E2 in mice bearing the HSDM1 fibrosarcoma. (1977) (38)
Total thyroidectomy for occult familial medullary carcinoma of the thyroid in children. (1976) (38)
Evidence for increased synthesis as well as increased degradation of protein kinase C after treatment of human osteosarcoma cells with phorbol ester. (1987) (38)
Ionomycin acts as an ionophore to release TRH-regulated Ca2+ stores from GH4C1 cells. (1986) (37)
Characterization and regulation of receptors for epidermal growth factor in mouse calvaria. (1980) (37)
Immunocytochemical localization of calcitonin‐producing cells in a strumal carcinoid with amyloid stroma (1979) (36)
The mechanism of inactivation of S-adenosylhomocysteinase by 2'-deoxyadenosine. (1980) (36)
Thyrotropin-releasing hormone and epidermal growth factor stimulate prolactin synthesis by a pathway(s) that differs from that used by phorbol esters: dissociation of actions by calcium dependency and additivity. (1985) (36)
The syndrome of multiple mucosal neuromas and medullary thyroid carcinoma in childhood (1975) (35)
Distribution of calcitonin-containing cells in the normal neonatal human thyroid gland: a correlation of morphology with peptide content. (1975) (35)
Relationship between biological responsiveness to phorbol esters and receptor levels in GH4C1 rat pituitary cells. (1981) (35)
Induction of prolactin synthesis in rat pituitary tumor cells by 5-bromodeoxyuridine (1977) (35)
C-cell granule heterogeneity in man. An ultrastructural immunocytochemical study. (1978) (34)
Dietary menhaden oil lowers plasma prostaglandins and calcium in mice bearing the prostaglandin-producing HSDM1 fibrosarcoma. (1984) (34)
Homeostasis of plasma calcium: effects of actinomycin D, parathyroidectomy and thyrocalcitonin. (1965) (34)
Subsecond and second changes in inositol polyphosphates in GH4C1 cells induced by thyrotropin-releasing hormone. (1987) (34)
Human milk lipids. 3. Short-term effects of dietary carbohydrate and fat. (1965) (33)
Acute phase reactants ceruloplasmin and haptoglobin and their relationship to plasma prostaglandins in rabbits bearing the VS2 carcinoma (1978) (33)
Animal cell cultures as a source of hormones (1969) (32)
Two squamous cell carcinomas not associated with humoral hypercalcemia produce a potent bone resorption-stimulating factor which is interleukin-1 alpha. (1989) (32)
Loss of growth hormone production following hybridization of a functional rat pituitary cell strain with a mouse fibroblast line. (1971) (31)
Systemic effects of the VX2 carcinoma on the osseous skeleton. A quantitative study of trabecular bone. (1978) (31)
Protein kinase Cepsilon is oncogenic in colon epithelial cells by interaction with the ras signal transduction pathway. (1998) (30)
Chromosomal analysis, organ-specific function and appearance of six clonal strains of rat pituitary tumor cells. (1970) (29)
Hyperparathyroidism due to clear cell hyperplasia. Serial determinations of serum ionized calcium, parathyroid hormone and calcitonin. (1973) (29)
Immunochemical relatedness of porcine, bovine, ovine and primate pituitary growth hormones. (1965) (29)
PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells. (1999) (29)
Direct modulation by androgens of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTH-related protein. (1989) (29)
Ionomycin inhibits thyrotropin-releasing hormone-induced translocation of protein kinase C in GH4C1 pituitary cells. (1987) (28)
STUDIES OF GROWTH HORMONE BY MICRO‐COMPLEMENT FIXATION * (1968) (27)
Functional receptors for epidermal growth factor on human osteosarcoma cells (1981) (26)
Thyrotropin-releasing hormone activates Na+/H+ exchange in rat pituitary cells. (1987) (26)
Cellular immune responses in familial medullary thyroid carcinoma. (1977) (25)
Beta-adrenergic receptor kinase-1 acutely regulates PTH/PTHrP receptor signalling in human osteoblastlike cells. (1997) (25)
IMMUNOASSAY OF PARATHYROID HORMONE BY QUANTITATIVE COMPLEMENT FIXATION. (1964) (25)
Management of parathyroid glands in surgery for medullary thyroid carcinoma. (1975) (25)
2-Thiophenecarboxylic acid: a hypoglycemic, antilipolytic agent with hypocalcemic and hypophosphatemic effects in rats. (1969) (24)
Time-dependent changes in protein kinase C distribution and disappearance in phorbol ester-treated human osteosarcoma cells. (1987) (24)
Association of phorbol ester receptor down modulation with a cryptic receptor state. (1983) (24)
METABOLISM OF BILIRUBIN BY A CLONAL STRAIN OF RAT HEPATOMA CELLS (1970) (24)
Medullary thyroid carcinoma detected by serum calcitonin assay. (1972) (23)
Antibodies to porcine thyrocalcitonin: effects on the hypocalcemic activity of calf, rat and monkey thyroid extracts. (1965) (23)
Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells. (1981) (23)
Medullary thyroid carcinoma: ectopic production of peptides with ACTH-like, corticotrophin releasing factor-like and prolactin production-stimulating activities. (1976) (23)
Platelet-derived growth factor increases prostaglandin production and decreases epidermal growth factor receptors in human osteosarcoma cells. (1982) (22)
Plasma calcitonin in pycnodysostosis: intermittently high basal levels and exaggerated responses to calcium and glucagon infusions. (1973) (22)
Adenylyl cyclase and cyclic nucleotide phosphodiesterases in GH-Strains of rat pituitary cells. (1977) (22)
Tumor Humors and the Hypercalcemias of Cancer (1974) (21)
Evidence for multiple intracellular calcium pools in GH4C1 cells: investigations using thapsigargin. (1991) (21)
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells. (1970) (21)
Modulation by 1,25-dihydroxycholecalciferol of the acute change in cytosolic free calcium induced by thyrotropin-releasing hormone in GH4C1 pituitary cells. (1988) (21)
Transient neonatal hypocalcemia, hypomagnesemia, and high serum parathyroid hormone with maternal hyperparathyroidism. (1975) (21)
Identification of aromatase activity in rodent pituitary cell strains. (1983) (21)
Inhibition by ouabain of parathyroid hormone-stimulated bone resorption. (1981) (20)
Identification of distinct signalling pathways for somatostatin receptors SSTR1 and SSTR2 as revealed by microphysiometry. (1999) (20)
Immunochemical studies with antisera to fractions of human growth hormone which are high or low in pigeon crop gland-stimulating activity. (1965) (20)
DL-threo-beta-Fluoroaspartate and DL-threo-beta-fluoroasparagine: selective cytotoxic agents for mammalian cells in culture. (1982) (20)
Role of the osteoclast in prostaglandin E2-stimulated bone resorption: a correlative morphometric and biochemical analysis. (1980) (20)
Localization of residual medullary thyroid cancer by thallium/technetium scintigraphy. (1985) (20)
Squamous cell carcinomas often produce more than a single bone resorption-stimulating factor: role of interleukin-1 alpha*. (1990) (19)
Insulin-like growth factor-I inhibits parathyroid hormone-stimulated and enhances prostaglandin E2-stimulated adenosine 3',5'-monophosphate production by human osteoblast-like SaOS-2 cells. (1993) (19)
p21Waf1/Cip1 and p53 are downstream effectors of protein kinase C delta in tumor suppression and differentiation in human colon cancer cells (2005) (19)
Unexpected resistance to x-irradiation in a strain of hybrid mammalian cells. (1972) (19)
Medullary carcinoma of the thyroid gland: the complete syndrome in a child. (1973) (19)
Relationship between mezerein-mediated biological responses and phorbol ester receptor occupancy. (1983) (19)
Production of an antibody to bovine parathyroid hormone. (1962) (19)
Influence of exogenous gonadotropins, antibody formation, and hysterectomy on the duration of luteal function in hypophysectomized rats. (1970) (18)
Extended RNA synthesis in isolated nuclei from rat pituitary tumor cells. (1976) (18)
Serum albumin production by hepatoma cells in culture: direct evidence for stimulation by hydrocortisone. (1969) (18)
Mechanism of parathyroid hormone action: effects of actinomycin D on hormone-stimulated ion movements in vivo and in vitro. (1964) (18)
Measurement of thyrocalcitonin-like activity in urine of patients with medullary carcinoma. (1971) (18)
pH homeostasis in pituitary GH4C1 cells: basal intracellular pH is regulated by cytosolic free Ca2+ concentration. (1992) (17)
Acute phase reactants ceruloplasmin and haptoglobin and their relationship to plasma prostaglandins in rabbits bearing the VX2 carcinoma (1978) (17)
Clonal strains of rat medullary thyroid carcinoma cells that produce neurotensin and calcitonin. Functional and morphologic studies. (1983) (17)
Platelet-derived growth factor selectively decreases prolactin production in pituitary cells in culture. (1983) (17)
Importance of transients in cytosolic free calcium concentrations on activation of Na+/H+ exchange in GH4C1 pituitary cells. (1991) (17)
Degradation of thyrotropin-releasing hormone by the GH3 strain of pituitary cells in culture. (1975) (17)
Evidence that the thyrotropin-releasing hormone receptor and its ligand are recycled dissociated from each other. (1995) (16)
Inhibition of capacitative Ca2+ entry into cells by farnesylcysteine analogs. (1996) (16)
Subcellular localization of thyrocalcitonin. (1966) (16)
Establishment of a calcitonin-producing rat medullary thyroid carcinoma cell line. I. Morphological studies of the tumor and cells in culture. (1980) (16)
Action of cholera toxin on hormone synthesis and release in GH cells: evidence that adenosine 3',5'-monophosphate does not mediate the decrease in growth hormone synthesis caused by thyrotropin-releasing hormone. (1980) (16)
Intrinsic tryptophan fluorescence of membranes of GH3 pituitary cells: quenching by thyrotropin-releasing hormone. (1975) (16)
Analysis by high performance liquid chromatography of cyclooxygenase products of arachidonic acid metabolism in plasma of rabbits bearing the VX2 carcinoma. (1980) (16)
Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae. (1987) (16)
Structural basis for the binding specificity of a SSTR1-selective analog of somatostatin. (1999) (15)
Actions of palytoxin on Na+ and Ca2+ homeostasis in human osteoblast-like Saos-2 cells. (1995) (15)
Inhibition of stimulated bone resorption by vanadate. (1983) (15)
Hormonal control of tyrosine aminotransferase, prolactin, and growth hormone induction in somatic cell hybrids. (1980) (15)
Importance of extracellular domains for ligand binding in the thyrotropin-releasing hormone receptor. (1995) (14)
Possible linear order of genes for endocrine neoplasia type 2, the P red cell antigen and HL-A on chromosome 6. (1976) (14)
Immunocytochemical analysis of prolactin production by monolayer cultures of GH3 rat anterior pituitary tumor cells: II. Variation in prolactin content of individual cell colonies, and dynamics of stimulation with thyrotropin‐releasing hormone (TRH) (1980) (14)
Regulation of neurotensin release by a continuous line of mammalian C-cells: the role of biogenic amines. (1983) (14)
Thyrotropin-releasing hormone modulation of uridine uptake in rat pituitary cells. Evidence that uridine phosphorylation is regulated. (1978) (13)
Rapid, quantitative estimation of human placental lactogen in maternal serum by complement fixation. (1970) (13)
Mechanisms of activation of Na+/H+ exchange in human osteoblast-like SaOS-2 cells. (1992) (13)
ASSAY OF HUMAN PARATHYROID HORMONE. (1964) (13)
Prostaglandin-induced bone resorption by rheumatoid synovia. (1975) (13)
Intracellular site of prolactin synthesis in rat pituitary cells in culture. (1974) (13)
Use of GH4C1 cell variants to demonstrate a non-spare receptor model for thyrotropin-releasing hormone action (1985) (13)
Regulation of endogenous thyrotropin-releasing hormone (TRH) receptor messenger RNA by TRH in GH4C1 cells. (1993) (13)
Thyrocalcitonin: Ultracentrifugation in Gradients of Sucrose (1966) (13)
Identification of Asn289 as a ligand binding site in the rat thyrotropin-releasing hormone (THR) receptor as determined by complementary modifications in the ligand and receptor: a new model for THR binding. (1995) (13)
Incorporation of beta-fluoroasparagine into peptides prevents N-linked glycosylation. In vitro studies with synthetic fluoropeptides. (1986) (13)
MEN-2 tumor associations suggest a linear order of specific endocrine tumor genes. (1989) (12)
Transcriptional regulation by dexamethasone of endogenous thyrotropin-releasing hormone receptor messenger ribonucleic acid in rat pituitary GH4C1 cells. (1993) (12)
Protein phosphatase inhibitors and bone resorption: inhibition by okadaic acid and biphasic actions of calyculin-A. (1992) (12)
Role of protein kinase A in the regulation of cytosolic free calcium in human osteoblast-like SaOS-2 cells. (1993) (12)
proTRH gene expression by fetal pancreatic islets in culture. (1990) (11)
Comparison of the inhibitory effects of propargylamine and pargyline on brain and liver monoamine oxidase activity. (1975) (11)
Involvement of alkaline phosphatase in the modulation of receptor signaling in osteoblasts: Evidence for a difference between human parathyroid hormone‐related protein and human parathyroid hormone (1994) (11)
Effects of parathyroidectomy and cautery of the thyroid gland on the plasma calcium level of rats with autotransplanted parathyroid glands. (1966) (11)
Regulation of endogenous thyrotropin-releasing hormone receptor messenger RNA in GH4C1 cells: roles of protein and RNA synthesis. (1993) (11)
p21(Waf1/Cip1) and p53 are downstream effectors of protein kinase C delta in tumor suppression and differentiation in human colon cancer cells. (2005) (11)
Thyrotropin-releasing hormone modulation of uridine uptake in rat pituitary cells. Characterization of the responses. (1978) (11)
Familial medullary thyroid carcinoma and pheochromocytoma: epidemiologic investigations. (1974) (11)
Chemical nature and properties of parathyroid hormones. (1963) (11)
Pseudohypoparathyroidism: no improvement following total thyroidectomy. (1969) (11)
Protein kinase A-dependent inhibition of alkaline phosphatase release by SaOS-2 human osteoblastic cells: studies in new mutant cell lines that express a cyclic AMP-resistant phenotype. (1991) (10)
Stimulation of bone resorption in organ culture by cholera toxin. (1981) (10)
Immunocytochemical analysis of prolactin production by monolayer cultures of GH3 rat anterior pituitary tumor cells: I. Long‐term effects of stimulation with thyrotropin‐releasing hormone (TRH) (1980) (10)
Relationships between amplitudes and kinetics of rapid cytosolic free calcium fluctuations in GH4C1 rat pituitary cells: roles for diffusion and calcium-induced calcium release. (1994) (10)
Forskolin-induced homologous desensitization via an adenosine 3',5'-monophosphate-dependent mechanism(s) in human osteoblast-like SaOS-2 cells. (1992) (10)
Agranulocytosis associated with phenindione: a case report with review of the literature. (1960) (9)
Antropyloric G-cell hyperplasia in hypercalcemic rabbits bearing the VX2 carcinoma. (1977) (9)
Impact of prospective screening for multiple endocrine neoplasia type 2. (1987) (9)
12-O-tetradecanoyl-phorbol-13-acetate decreases influx of extracellular Ca2+ induced by depolarization in GH4C1 cells: effects of pretreatment with 1,25-dihydroxycholecalciferol. (1990) (9)
Diagnostic dependability of calcitonin assay in family studies for medullary thyroid carcinoma. (1971) (9)
Palytoxin modulates cytosolic pH in human osteoblast-like Saos-2 cells via an interaction with Na(+)-K(+)-ATPase. (1996) (9)
Solubilization of receptors for thyrotropin-releasing hormone from GH4C1 rat pituitary cells: demonstration of guanyl nucleotide sensitivity. (1987) (9)
Clinical value of tumor doubling estimations in multiple endocrine neoplasia type II. (1984) (9)
17 – Human Calcitonin: Application of Affinity Chromatography (1978) (8)
Hormonal regulation of cytosolic free calcium and its functional consequences: the GH-cell model. (1990) (8)
User-friendly and versatile software for analysis of protein hydrophobicity. (1998) (8)
Cyclic ADP-ribose-induced calcium release in sea urchin egg homogenates is a cooperative process. (1995) (8)
Distribution of thyroid, parathyroid, and ultimobranchial hypocalcemic factors in birds. II. Morphology, Histochemistry, and hypocalcemic activity of pigeon thyroid glands (1973) (8)
Stability of the hypocalcemic activity of porcine thyrocalcitonin. (1967) (8)
Antitumor activity of DL-threo-beta-fluoroasparagine against human leukemia cells in culture and L1210 cells in DBA mice. (1984) (8)
Evidence for multiple bone resorption-stimulating factors produced by normal human keratinocytes in culture. (1988) (7)
Control of intracellular calcium redistribution by guanine nucleotides and inositol 1,4,5-trisphosphate in permeabilized GH4C1 cells. (1991) (7)
Platelet-activating factor affects cytosolic free calcium concentration and prolactin secretion in GH4C1 rat pituitary cells. (1991) (7)
Unexpectedly high biological activity of synthetic human calcitonin. (1970) (7)
Distribution of thyroid, parathyroid, and ultimobranchial hypocalcemic factors in birds. 1. Thyroid and ultimobranchial calcitonins in pigeons and pullets. (1972) (7)
Decreased thyrocalcitonin in thyroid glands from patients with hyperparathyroidism. (1967) (6)
Rabbit, guinea pig, rat and human antibodies to human growth hormone: immunological reactions with human and nonhuman primate growth hormones. (1966) (6)
Clonal analysis of a 5-azacytidine-induced specific increase in growth hormone production by rat pituitary cells. (1983) (6)
Pretreatment with 17β-Estradiol Attenuates Basal- and PTH-Stimulated Membrane Adenylyl Cyclase Activity in Human Osteoblast-like SAOS-2 Cells (1996) (6)
PARTIAL HYDROLYSIS OF BOVINE PARATHYROID HORMONE BY DILUTE ACID AND PROTEOLYTIC ENZYMES: EFFECTS ON IMMUNOLOGICAL AND BIOLOGICAL ACTIVITIES. (1965) (6)
The thyrotropin-releasing hormone-receptor complex and G11alpha are both internalised into clathrin-coated vesicles. (1998) (6)
Kinetics and reversibility of thyrotropin-releasing hormone-stimulated guanine nucleotide exchange in membranes from GH4C1 cells. (1994) (5)
Pituitary immunoreactive calcitonin-like material: lack of evidence for cross-reactivity with pro-opiomelanocortin. (1983) (5)
Parathyroid hormone and calcitonin interactions in bone: Irradiation-induced inhibition of escape in vitro (1982) (5)
Labeled Bilirubin Production by a Clonal Strain of Rat Hepatoma Cells 1 (1971) (5)
Voltage-dependent Calcium Channels in Pituitary Cells in Culture (2001) (4)
KINETICS OF HUMAN CITRATE METABOLISM: STUDIES IN NORMAL SUBJECTS AND IN PATIENTS WITH BONE DISEASE. (1963) (4)
Clinical value of calcitonin and carcinoembryonic antigen doubling times in medullary thyroid carcinoma. (1987) (4)
Alterations in the frequency and shape of Ca2+ fluctuations in GH4C1 cells induced by thyrotropin-releasing hormone and Bay K 8644. (1995) (4)
Ca2+ and Extracellular Acidification Rate Responses to Parathyroid Hormone Fragments in Rat ROS 17/2 and Human SaOS-2 Cells (1999) (4)
Use of minoxidil to demonstrate that prostacyclin is not the mediator of bone resorption stimulated by growth factors in mouse calvariae. (1988) (4)
Human medullary thyroid carcinoma: control of calcitonin secretion in vivo and in tissue culture. (1974) (4)
Thyrocalcitonin: partition on carboxymethyl-sephadex C-25 and characterization by disc gel electrophoresis. (1967) (4)
Letter: Whence the calcitonin. (1973) (3)
Drug Toxicity. (1964) (3)
Soft bones, hard facts and calcitonin therapy. (1970) (3)
Quenching of intrinsic tryptophan fluorescence in membranes of rat pituitary cells. (1979) (3)
Thyrotropin-releasing hormone increases prolactin mRNA activity in the cytoplasm of GH-cells as measured by translation in a wheat germ cell-free system. (1976) (3)
Calcium regulating hormones and bone metabolism : basic and clinical aspects, vol. 11 : proceedings of the 11th International Conference on Calcium Regulating Hormones, Florence, 24-29 April 1992 (1992) (2)
Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin. (1974) (2)
Immunochemistry of thyrocalcitonins species differences and studies of the relationships between structure and immunological activity (1970) (2)
Studies in familial thyroid cancer. (1971) (2)
Novel action of pituitary adenylate cyclase-activating polypeptide. Stimulation of extracellular acidification in rat pituitary GH4C1 cells. (2000) (2)
Inhibition of asparagine-linked glycosylation of pro-opiomelanocortin in mouse pituitary cells by DL-threo-beta-fluoroasparagine. (1983) (2)
DL-THREO-β-FLUOROASPARTATE AND LD-THREO-β-FLUOROASPARAGINE: SELECTIVE CYTOTOXIC AGENTS FOR MAMMALIAN CELLS IN CULTURE (1982) (2)
Regulation of pHi in Saos-2 cells by thrombin: roles of proteolytic activity and cytosolic calcium transients. (1992) (2)
New insights into interactions between the human PTH/PTHrP receptor and agonist/antagonist binding. (1998) (2)
The syndrome of multiple aucosal neuromas and medullary thyroid carcinoma in childhood. Importance of recognition of the phenotype for the early detection of malignancy. (1975) (2)
Inhibition of parathyroid hormone-stimulated bone resorption by monovalent cation ionophores (1982) (2)
Letter: Prostaglandins, bone resorption and hyperglycemia. (1974) (2)
Inhibition of monoamine oxidase activity by propargylamine in pituitary cells in culture: lack of effect on cell growth or proclactin production☆ (1974) (2)
Regulation of Prolactin and Growth Hormone Production by Clonal Strains of Functional Pituitary Cells in Culture (1975) (1)
Control of the production of two protein hormones by rat pituitary cells in culture (1970) (1)
Inhibition of monoamine oxidase activity by propargylamine in pituitary cells in culture: lack of effect on cell growth or prolactin production. (1974) (1)
Pretreatment with 17 beta-estradiol attenuates basal- and PTH-stimulated membrane adenylyl cyclase activity in human osteoblast-like SAOS-2 cells. (1996) (1)
Ca(2+) and extracellular acidification rate responses to parathyroid hormone fragments in rat ROS 17/2 and human SaOS-2 cells. (1999) (1)
Toward an Understanding of Human Parathyroid Hormone Structure and Function (2005) (1)
PROLACTIN‐PRODUCING CELLS IN CULTURE: CONTROL OF HORMONE BIOSYNTHESIS AND RELEASE (1977) (1)
Comparative C19-radiosteroid metabolism by MA 160 and HeLa cell lines (1977) (1)
Editorial: Prostaglandins, hypercalcemia and cancer. (1975) (1)
Voltage-dependent Calcium Channels in Pituitary Cells in Culture 11 (2001) (1)
High-sensitivity serum calcitonin assays applied to screening for thyroid C-cell disease in multiple endocrine neoplasia type 2A. (1992) (1)
Parathyroid gland. (1963) (1)
Production and characterization of an antiserum which recognizes the native receptor for thyrotropin-releasing hormone. (2001) (1)
Natural history of familial medullary carcinoma of the thyroid gland (MCT) pheochromocytoma syndrome and the identification of preneoplastic stages by screening tests. A five year report (1975) (1)
Case report. Blood-streaked sputum. (1974) (0)
Evaluation of Thyroid and Parathyroid Functions. Proceedings of the Third Applied Seminar of the Association of Clinical Scientists.F. William Sunderman , F. William Sunderman, Jr. (1965) (0)
MOLECULAR MODEL OF PTHRP (1-34) IN COMPLEX WITH THE PTH/PTHRP RECEPTOR (PTHR1). (2000) (0)
Oral abstractIntracellular calcium mobilization: Molecular cloning of the rat lactotroph thyrotropin-releasing hormone receptor and the actions of cyclic ADP-ribose in mammalian cells (1992) (0)
Time-dependent Changes in Protein Kinase C Distribution and Disappearance in Phorbol Ester-treated Human Osteosarcoma Cells 1 (2006) (0)
(TRH) Receptor Messenger RNA by TRH in GH&, Cells (1993) (0)
Studies on the potentiation of the calcium-mobilizing activity of parathyroid hormone by cysteine hydrochloride and gelatin. (1970) (0)
ACUTE PHASE REACTANTS CERULOPLASMIN AND HAPTOGLOBIN AND THEIR RELATIONSHIP TO PLASMA PROSTAGLANDINS IN RABBITS BEARING THE VX~ CARCINOMA* (2003) (0)
Synthesis and characterization of a high-affinity photoactivatable analogue of thyrotropin-releasing hormone. (1992) (0)
MOLECULAR MODEL OF THE CRYSTAL STRUCTURE OF HUMAN PARATHYROID HORMONE 1-34 COMPLEXED WITH PTH/PTHRP RECEPTOR. (2000) (0)
Effects of L-dopa and bromocriptine on calcitonin secretion in medullary thyroid carcinoma. (1980) (0)
Introduction to hormones as signals and hormones as products of animal cells in culture (1970) (0)
Radioimmunoassay for phorbol esters using rabbit antisera against phorbol succinate. (1985) (0)
Unexpected Resistance toX-Irradiation inaStrain ofHybridMammalianCells (mousefibroblasts/!rat pituitary cells/chromosome number) (1972) (0)
Mechanisms of bone remodeling induced by tumors: tumor humors. (1981) (0)
Thyrotropin-releasing Hormone Modulation of Uridine Uptake in Rat Pituitary Cells (2011) (0)
Radioimmunoassayfor PhorbolEsters UsingRabbitAntiseraagainst Phorbol (2006) (0)
a and f 3 human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria ( bone resorption / prostaglandin E 2 ) (0)
Editorial: Tumor humors and the hypercalcemias of cancer. (1974) (0)
Effects of Endopeptidases, Heat and Oxidizing Agents on the Hypocalcemic Activity of Porcine Thyrocalcitonin1 (1968) (0)
Antitumor Activity of DL-ffÃ ̄ reo-0-Fluoroasparagine against Human Leukemia Cells in Culture and L 1210 Cells in DBA Mice 1 (2006) (0)
New insights into interactions between the human PTH/PTHrP receptor and agonist/antagonist binding. (1998) (0)
Cells Disappearance in Phorbol Ester-treated Human Osteosarcoma Time-dependent Changes in Protein Kinase C Distribution and Updated Version (2006) (0)
Time-dependent Changes in Protein Kinase C Distribution and Disappearance in Phorbol Ester-treated Human Osteosarcoma Cells1 (2006) (0)
The inositol lipid signalling system: generation of multiple intracellular messenger molecules. (1990) (0)
VIP and bone: Evidence for neural control of bone resorption (1985) (0)
Oral antibiotics and serum cholesterol level in man. (1963) (0)
Multiple differentiated functions in an unusual clonal strain of hepatoma cells (1970) (0)

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