Andrej Hasilik
#161,553
Most Influential Person Now
Andrej Hasilik's AcademicInfluence.com Rankings
Andrej Hasilikbiology Degrees
Biology
#12828
World Rank
#16331
Historical Rank
Biochemistry
#2217
World Rank
#2363
Historical Rank
Download Badge
Biology
Why Is Andrej Hasilik Influential?
(Suggest an Edit or Addition)Andrej Hasilik's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Lysosomal enzymes and their receptors. (1986) (794)
- Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight. (1980) (582)
- Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues. (1980) (335)
- Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver (1984) (320)
- Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in I-cell fibroblasts. (1981) (241)
- Possible pathways for lysosomal enzyme delivery (1985) (237)
- Biosynthesis and transport of cathepsin D in cultured human fibroblasts (1983) (214)
- The proteome of lysosomes (2010) (201)
- Integral and Associated Lysosomal Membrane Proteins (2007) (184)
- Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae. (1981) (159)
- UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus. (1991) (153)
- Processing of human cathepsin D in lysosomes in vitro. (1985) (153)
- Ultrastructural localization of the mannose 6-phosphate receptor in rat liver (1984) (143)
- Biosynthesis of the vacuolar yeast glycoprotein carboxypeptidase Y. Conversion of precursor into the enzyme. (1978) (140)
- Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2. (1982) (138)
- Mr 46,000 mannose 6‐phosphate specific receptor: its role in targeting of lysosomal enzymes. (1987) (136)
- Deficiency of UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients. (1982) (127)
- Processing of the phosphorylated recognition marker in lysosomal enzymes. Characterization and partial purification of a microsomal alpha-N-acetylglucosaminyl phosphodiesterase. (1981) (123)
- Carbohydrate moiety of carboxypeptidase Y and perturbation of its biosynthesis. (1978) (117)
- Selective inactivity of TGF‐β/decorin complexes (1994) (113)
- Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes? (1987) (108)
- Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups. (1980) (92)
- Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II (2004) (83)
- Mannose 6-phosphate/insulin-like growth factor II receptor: distinct binding sites for mannose 6-phosphate and insulin-like growth factor II. (1988) (83)
- Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus. (1982) (81)
- Carbohydrate-free carboxypeptidase Y is transferred into the lysosome-like yeast vacuole. (1982) (81)
- Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation. (2004) (81)
- Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders (1998) (80)
- Biosynthesis of lysosomal enzymes (1980) (78)
- Antibody to mannose 6‐phosphate specific receptor induces receptor deficiency in human fibroblasts. (1984) (78)
- Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease. (1987) (75)
- Molecular organization of the human cathepsin D gene. (1991) (70)
- Oligosaccharides in Lysosomal Enzymes (1981) (66)
- Subcellular location of two enzymes involved in the synthesis of phosphorylated recognition markers in lysosomal enzymes. (1981) (66)
- Neutral endopeptidase-24.11 (enkephalinase). Biosynthesis and localization in human fibroblasts. (1987) (64)
- Theearly andlate processing of lysosomal enzymes: Proteolysis and compartmentation (1992) (61)
- Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways (1987) (61)
- Juvenile and adult metachromatic leukodystrophy: partial restoration of arylsulfatase A (cerebroside sulfatase) activity by inhibitors of thiol proteinases. (1983) (60)
- On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells. (1987) (59)
- Enhanced breakdown of arylsulfatase A in multiple sulfatase deficiency. (1982) (58)
- Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase. (1987) (57)
- UDP-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase. Partial purification and characterization of the rat liver Golgi enzyme. (1982) (55)
- Cathepsin D expression is decreased in Alzheimer's disease fibroblasts (2008) (55)
- Myeloperoxidase is synthesized as larger phosphorylated precursor. (1984) (55)
- 46-kDa mannose 6-phosphate-specific receptor: biosynthesis, processing, subcellular location and topology. (1987) (54)
- Biosynthesis and transport of lysosomal enzymes in human monocytes and macrophages. Effects of ammonium chloride, zymosan and tunicamycin. (1983) (53)
- Effect of monensin on intracellular transport and receptor-mediated endocytosis of lysosomal enzymes. (1984) (53)
- Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum. (1984) (53)
- Identification of plasma membrane associated mature β‐hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts (2005) (52)
- Molecular forms of beta-hexosaminidase and cathepsin D in serum and urine of healthy subjects and patients with elevated activity of lysosomal enzymes. (1983) (52)
- Amplified Crevicular Leukocyte Activity in Aggressive Periodontal Disease (2002) (52)
- Internalization of blocking antibodies against mannose‐6‐phosphate specific receptors. (1985) (51)
- PMN responses in chronic periodontal disease: evaluation by gingival crevicular fluid enzymes and elastase-alpha-1-proteinase inhibitor complex. (2002) (51)
- Synthesis and processing of arylsulfatase A in human skin fibroblasts. (1982) (50)
- Cathepsin D precursors in clathrin-coated organelles from human fibroblasts (1985) (49)
- Compartmentation of the tryptophan-synthase-proteolyzing system in Saccharomyces cerevisiae. (1974) (49)
- Identification of a Lysosomal Peptide Transport System Induced during Dendritic Cell Development* (2007) (44)
- Selective inactivity of TGF-beta/decorin complexes. (1994) (44)
- 46-kDa mannose 6-phosphate-specific receptor: purification, subunit composition, chemical modification. (1987) (44)
- Molecular characterisation of ‘transmembrane protein 192’ (TMEM192), a novel protein of the lysosomal membrane (2010) (43)
- Synthesis and transport of lysosomal acid phosphatase in normal and I-cell fibroblasts. (1985) (43)
- Biosynthesis and maturation of arylsulfatase B in normal and mutant cultured human fibroblasts. (1983) (41)
- Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog beta-hydroxynorvaline. (1984) (40)
- Biosynthesis of glycosylated human lysozyme mutants. (1991) (40)
- IL-10 Synergizes with IL-4 and IL-13 in Inhibiting Lysosomal Enzyme Secretion by Human Monocytes and Lamina Propria Mononuclear Cells from Patients with Inflammatory Bowel Disease (1998) (39)
- Transport and processing of lysosomal enzymes by smooth muscle cells and endothelial cells. (1981) (39)
- Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D (2003) (39)
- The catalytically inactive precursor of cathepsin D induces apoptosis in human fibroblasts and HeLa cells (2007) (38)
- Participation of the tryptophan synthase inactivating system from yeast in the activation of chitin synthase. (1973) (36)
- Biosynthesis of acid α‐glucosidase in late‐onset forms of glycogenosis type II (Pompe's disease) (1982) (35)
- Tilorone acts as a lysosomotropic agent in fibroblasts. (1984) (34)
- Suppression of the 'uncovering' of mannose-6-phosphate residues in lysosomal enzymes in the presence of NH4Cl. (1990) (32)
- Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol. (1985) (32)
- Tartrate-inhibitable acid phosphatase. Purification from placenta, characterization and subcellular distribution in fibroblasts. (1984) (31)
- The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC‐Coupling Reagents (2006) (31)
- Intracellular trafficking of lysosomal proteins and lysosomes. (2009) (31)
- Chondroitin sulfate is involved in lysosomal transport of lysozyme in U937 cells. (2001) (30)
- A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells. (2003) (29)
- Differential segregation of human and hamster cathepsin D in transfected baby-hamster kidney cells. (1991) (28)
- BIOSYNTHESIS OF LYSOSOMAL ENZYMES IN DIPLOID HUMAN FIBROBLASTS (1979) (28)
- Synthesis and stability of arylsulfatase A and B in fibroblasts from multiple sulfatase deficiency. (1985) (27)
- Expression and maturation of human cathepsin D in baby-hamster kidney cells. (1991) (27)
- Mis‐sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal (1997) (26)
- Presence of detergent-resistant microdomains in lysosomal membranes. (2002) (26)
- Immuno-electron microscopical demonstration of lysosomes in human blood platelets and megakaryocytes using anti-cathepsin D. (1985) (25)
- Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts. (1986) (25)
- Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. (2011) (24)
- Genetic interaction of the SMC complex with topoisomerase IV in Bacillus subtilis. (2005) (23)
- Porins facilitate nitric oxide-mediated killing of mycobacteria. (2009) (22)
- Membrane-active antimicrobial peptides and human placental lysosomal extracts are highly active against mycobacteria (2011) (22)
- Distinctive inhibition of the lysosomal targeting of lysozyme and cathepsin D by drugs affecting pH gradients and protein kinase C. (1994) (21)
- Synthesis of lysosomal α-mannosidase in normal and mannosidosis fibroblasts (1983) (21)
- Biosynthesis of carboxypeptidase Y in yeast. Evidence for a precursor form of the glycoprotein. (1976) (21)
- Biosynthesis and maturation of alpha-N-acetylglucosaminidase in normal and Sanfilippo B-fibroblasts. (1984) (21)
- NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. (2009) (21)
- Targeting myeloperoxidase to azurophilic granules in HL‐60 cells (2003) (21)
- Phosphorylation of lysosomal enzymes in fibroblasts. Marked deficiency of N-acetylglucosamine-1-phosphotransferase in fibroblasts of patients with mucolipidosis III. (1982) (20)
- Two allelic forms of human arylsulfatase A with different numbers of asparagine-linked oligosaccharides. (1983) (19)
- Inhibition by cyanate of the processing of lysosomal enzymes. (1983) (19)
- Association of the precursor of cathepsin D with coated membranes. Kinetics and carbohydrate processing. (1987) (19)
- Distribution and subcellular localization of a lysosome-associated protein in human genital organs (1997) (19)
- Resolution of crevicular fluid leukocyte activity in patients treated for aggressive periodontal disease. (2002) (18)
- Comparison of biosynthesis and subcellular distribution of lysozyme and lysosomal enzymes in U937 monocytes. (1985) (18)
- Calcitriol enhances transcriptional activity of lysozyme and cathepsin D genes in U937 promonocytes. (1989) (18)
- Neutrophil elastase is associated with serglycin on its way to lysosomes in U937 cells. (2007) (17)
- Human cathepsin D precursor is associated with a 60 kDa glycosylated polypeptide. (1992) (17)
- Immunocytochemical localisation of some lysosomal hydrolases, their presence in luminal fluid and their directional secretion by human epididymal cells in culture (1995) (17)
- Natural killer cell-mediated cytotoxicity does not depend on recognition of mannose 6-phosphate residues. (1985) (16)
- Immunoprecipitation of labeled antigens with Eupergit C1Z. (1989) (16)
- Low temperature blocks transport and sorting of cathepsin D in fibroblasts. (1988) (16)
- Effects of differentiation-inducing agents on synthesis, maturation and secretion of cathepsin D in U937 and HL-60 cells. (1987) (16)
- Saposin B-dependent Reconstitution of Arylsulfatase A Activity in Vitro and in Cell Culture Models of Metachromatic Leukodystrophy* (2009) (16)
- Heterogeneity in late-onset metachromatic leukodystrophy. Effect of inhibitors of cysteine proteinases. (1986) (16)
- Sulfated oligosaccharides in human lysosomal enzymes. (1987) (16)
- Lysosomal segregation of a mannose‐rich glycoprotein imparted by the prosequence of myeloperoxidase (1998) (16)
- Conditions for a reliable application of the lysoplate method in the determination of lysozyme. (1987) (16)
- Multiple sulfatase deficiency: degradation of arylsulfatase A and B after endocytosis in fibroblasts. (1985) (15)
- Protection of proteolysis-prone recombinant proteins in baculovirus expression systems. (1998) (15)
- Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts (1997) (15)
- Genesis of lysosomal enzyme deficiencies (1984) (15)
- Human and hamster procathepsin D, although equally tagged with mannose-6-phosphate, are differentially targeted to lysosomes in transfected BHK cells (1998) (14)
- High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells. (2006) (14)
- Synthesis and stability of steroid sulfatase in fibroblasts from multiple sulfatase deficiency. (1988) (14)
- Characterisation of lipofuscin‐like lysosomal inclusion bodies from human placenta (2007) (14)
- Determination of the Phosphorylation, Uncovering of Mannose 6-Phosphate Groups and Targeting of Lysosomal Enzymes (1991) (14)
- Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane. (2008) (13)
- Processing and transport of lysosomal enzymes in human monocyte line U937. (1984) (13)
- Oligosaccharides in lysosomal enzymes. Distribution of high-mannose and complex oligosaccharides in cathepsin D and beta-hexosaminidase. (1981) (12)
- Elevated Levels Of Activities Of β-Hexosaminidase And α-Mannosidase In Human Immunodeficiency Virus-Infected Patients (1995) (12)
- Synthesis and localization of myeloperoxidase protein in transfected BHK cells. (1989) (11)
- Elongation of N-acetyllactosamine repeats in diantennary oligosaccharides. (1997) (11)
- Sequential detection of antigens in Western blots with differently colored products. (1986) (11)
- Molecular forms of cathepsin D in coated vesicle preparations. (1983) (11)
- The cation‐independent mannose 6‐phosphate receptor is involved in lysosomal delivery of serglycin (2007) (10)
- PMN responses following use of 2 biodegradable GTR membranes. (2001) (10)
- Impaired phosphorylation of lysosomal enzymes in fibroblasts of patients with mucolipidosis III. (1982) (10)
- A protocol for combined delipidation and subfractionation of membrane proteins using organic solvents. (2006) (10)
- Brefeldin A prevents uncovering but not phosphorylation of the recognition marker in cathepsin D. (1990) (10)
- Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes. (2012) (9)
- Plasmid vectors with a 5'-hybrid intron facilitate high-level glycoprotein expression in CHO-cells. (2002) (9)
- Cell type dependent inhibition of transport of cathepsin D in HepG2 cells and fibroblasts exposed to deoxy-manno-nojirimycin and deoxynojirimycin. (1985) (9)
- LYSOSOMAL STORAGE DISORDERS CAUSED BY INSTABILITY OF THE MISSING ENZYMES (1984) (9)
- Synthesis of phosphorylated oligosaccharides in lysozyme is enhanced by fusion to cathepsin D. (1993) (9)
- A mild form of mucolipidosis type III in four Baluch siblings (1993) (9)
- Calmodulin antagonists increase the amount of mRNA for the low-density-lipoprotein receptor in skin fibroblasts. (1988) (8)
- Lysosomal membrane proteins do not bind to mannose-6-phosphate-specific receptors. (1986) (8)
- Inactivation of chitin synthase in Saccharomyces cerevisiae (2004) (8)
- Mutations affecting transport and stability of lysosomal enzymes. (1987) (8)
- Glycosylation of intra- and extra-cellular yeast glycoproteins. (1979) (7)
- Effects of antibiotics on the development and stability of mitochondrial enzymes in Saccharomyces cerevisiae. (1972) (7)
- Synthesis and Processing of a-Galactosidase A in Human Fibroblasts (1987) (7)
- Selective inactivity of TGF-fl / decorin complexes (2001) (6)
- Perturbation of Growth and Metabolism in Candida albicans by 4-Bromobenzyl Isothiocyanate and Iodoacetate (1973) (6)
- Membranes and their cellular functions, 3rd edn: by J. B. Finean, R. Coleman and R. H. Michell, Blackwell Scientific Publications, 1984. £9.80 (viii + 227 pages) ISBN 0 632 01204 8 (1985) (5)
- Biosynthesis of acid alpha-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease). (1982) (5)
- Human tartrate-inhibitable lysosomal acid phosphatase. Purification, characterization, biosynthesis and intracellular transport. (1986) (4)
- Biosynthesis, targeting, and processing of lysosomal proteins: pulse-chase labeling and immune precipitation. (2015) (4)
- Transport and Processing of Lysosomal Enzymes (1986) (4)
- Defects in lysosomal enzyme trafficking (2004) (3)
- Carbohydrate mediated recognition of lysosomal enzymes by cell surface receptors (1983) (3)
- Synthesis and Secretion of Cathepsin D in Normal and Tumor Human Cells (1991) (3)
- The effect of 4-bromobenzyl isothiocyanate on the redox state of nicotinamide-adenine dinucleotides in Candida albicans. (1972) (3)
- Synthesis of lysosomal alpha-mannosidase in normal and mannosidosis fibroblasts. (1983) (3)
- Origin and Dynamics of Lysosomes (1980) (3)
- Glycosylation-site-selective synthesis of N-acetyl-lactosamine repeats in bis-glycosylated human lysozyme. (2000) (3)
- Receptor-dependent transport of lysosomal enzymes. (1988) (2)
- Increased elongation of N-acetyllactosamine repeats in doubly glycosylated lysozyme with a particular spacing of the glycosylation sites (1998) (2)
- Elevated levels of activities of beta-hexosaminidase and alpha-mannosidase in human immunodeficiency virus-infected patients. (1995) (2)
- Some aspects of the regeneration of Candida albicans after inhibition of the energy metabolism. (1969) (1)
- Disrupted in renal carcinoma 2 ” ( DIRC 2 )-a novel transporter of the lysosomal membrane-is proteolytically processed by cathepsin L Short title : DIRC 2-a new lysosomal transporter (2017) (1)
- Successful Expression of a Selenomethionyl Protein under Control of th e Temperature-Sensitive λ λ Repressor Require s Higher than Norma l Temperatur e (1998) (1)
- Abstract 5179: Inhibition of U937-cell adhesion to human endothelial cells by glycosylated lysozyme mutants (2012) (0)
- Effect of antibiotics on the development and stability of mitochondrial enzymes in saccharomyces cerevisiae. (1972) (0)
- Effects of NH4Cl on the processing of phosphorylated cathepsin D (1990) (0)
- Recognition Marker in Lysosomal Enzymes: Presence of α-N-acetylglucosamine(1)phospho(6)mannose Diester Groups (1981) (0)
- 108th Conference of the Gesellschaft für Biologische Chemie. 5th Joint Meeting of the Nederlandse Vereniging voor de Bestudering van Glycoconjugaten and the Studiengruppe Glykokonjugate der GBCh (1993) (0)
- CARBOHYDRATE MOIETIES OF LYSOSOMAL ENZYMES AS TRANSPORT SIGNALS (1981) (0)
- On the Biosynthesis of Carboxypeptidase Y (CY) (1979) (0)
- Immunity to mycobacterial infection (PP-061) (2010) (0)
- Targeting of Proteins to Lysosomes and Granules (2000) (0)
- P4-186 Regulation of lysosomal enzymes expression in fibroblasts from Alzheimer's disease patients (2004) (0)
- Endosomal targeting and secretion of lysosomal proteins in U 937 cells INAUGURAL (2008) (0)
- Processing of the Phosphorylated Recognition Marker in Lysosomal Enzymes AND PARTIAL PURIFICATION OF A MICROSOMAL (u-N-ACETYLGLUCOSAMINYL (1981) (0)
- Netherlands Society for Microbiology meeting at Rotterdam on 8 December 1971 (2006) (0)
- Correction of Lysosomal Enzyme Deficiences by Enzyme Replacement (1981) (0)
- Altered transport and processing of cathepsin D in human tumour cells with metastatic phenotype (1991) (0)
- Humanlysosomal acidphosphatase: cloning, expression andchromosomal assignment (1988) (0)
- DEFECTIVE PROCESSING OF LYSOSOMAL ENZYMES (1986) (0)
- expression and processing of cathepsin D in fibroblasts of patients with Alzheimer's Disease (2004) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Andrej Hasilik?
Andrej Hasilik is affiliated with the following schools:
