Arthur I. Cederbaum
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Biology
Why Is Arthur I. Cederbaum Influential?
(Suggest an Edit or Addition)Arthur I. Cederbaum's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Mechanisms of hepatotoxicity. (2002) (1258)
- Alcohol, Oxidative Stress, and Free Radical Damage (2003) (1081)
- CYP2E1 and oxidative liver injury by alcohol. (2008) (646)
- Alcohol and oxidative liver injury (2006) (528)
- Role of oxidative stress in alcohol-induced liver injury (2009) (518)
- Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems. (1981) (501)
- Oxidative stress, toxicology, and pharmacology of CYP2E1. (2004) (493)
- Alcohol metabolism. (2012) (474)
- Oxidative stress and alcoholic liver disease. (2009) (327)
- A high‐fat diet leads to the progression of non‐alcoholic fatty liver disease in obese rats (2005) (312)
- Overexpression of Catalase in Cytosolic or Mitochondrial Compartment Protects HepG2 Cells against Oxidative Injury* (1999) (286)
- Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production. (2004) (272)
- Cytochrome P450 2E1 contributes to ethanol‐induced fatty liver in mice (2008) (270)
- Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1–derived reactive oxygen species (2002) (259)
- Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates. (1993) (249)
- Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes. (1998) (241)
- CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. (2001) (212)
- Cytotoxicity and Apoptosis Produced by Arachidonic Acid in Hep G2 Cells Overexpressing Human Cytochrome P4502E1* (1997) (198)
- Effects of chronic ethanol treatment of mitochondrial functions damage to coupling site I. (1974) (196)
- Ethanol Cytotoxicity to a Transfected HepG2 Cell Line Expressing Human Cytochrome P4502E1* (1996) (196)
- Introduction-serial review: alcohol, oxidative stress and cell injury. (2001) (194)
- Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1 (2006) (188)
- Cytochrome P450 2E1-derived Reactive Oxygen Species Mediate Paracrine Stimulation of Collagen I Protein Synthesis by Hepatic Stellate Cells* (2002) (185)
- Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. (2010) (176)
- CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells (1999) (175)
- Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells. (1998) (173)
- Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1. (2006) (173)
- Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. (1995) (171)
- Role of lipid peroxidation and oxidative stress in alcohol toxicity. (1989) (165)
- Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment. (1994) (150)
- CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury. (2003) (149)
- The effect of acetaldehyde on mitochondrial function (1974) (142)
- Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment. (1993) (140)
- Diallyl sulfide induces heme oxygenase-1 through MAPK pathway. (2004) (131)
- The liver and blood coagulation: physiology and pathology. (1972) (130)
- Ethanol and Arachidonic Acid Increase α2(I) Collagen Expression in Rat Hepatic Stellate Cells Overexpressing Cytochrome P450 2E1 (2000) (124)
- CYP2E1 Overexpression in HepG2 Cells Induces Glutathione Synthesis by Transcriptional Activation of γ-Glutamylcysteine Synthetase* (2000) (124)
- Mitochondrial Catalase and Oxidative Injury (2001) (123)
- The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase. (1984) (118)
- Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1. (1999) (113)
- Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1. (1998) (112)
- Role of CYP2E1 in Ethanol-Induced Oxidant Stress, Fatty Liver and Hepatotoxicity (2011) (108)
- CYP2E1--biochemical and toxicological aspects and role in alcohol-induced liver injury. (2006) (107)
- Cytochrome P450 2E1‐dependent oxidant stress and upregulation of anti‐oxidant defense in liver cells (2006) (105)
- Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. (1983) (105)
- Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy. (2014) (105)
- Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications (2014) (102)
- NADPH-dependent production of oxy radicals by purified components of the rat liver mixed function oxidase system. I. Oxidation of hydroxyl radical scavenging agents. (1983) (99)
- Microsomal metabolism of hydroxyl radical scavenging agents: relationship to the microsomal oxidation of alcohols. (1980) (97)
- The effect of dimethylsulfoxide and other hydroxyl radical scavengers on the oxidation of ethanol by rat liver microsomes. (1977) (93)
- Intravascular coagulation with use of human prothrombin complex concentrates. (1976) (93)
- Alcohol‐induced liver injury in mice lacking Cu, Zn‐superoxide dismutase (2003) (93)
- Inhibition of the catalytic activity of alcohol dehydrogenase by nitric oxide is associated with S nitrosylation and the release of zinc. (1996) (93)
- Binge ethanol exposure increases liver injury in obese rats. (2003) (92)
- Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. (1989) (92)
- Catalase Protects HepG2 Cells from Apoptosis Induced by DNA-damaging Agents by Accelerating the Degradation of p53* (2003) (91)
- Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1. (2001) (90)
- Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. (2005) (88)
- Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1. (2001) (87)
- Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. (2012) (87)
- Effect of chronic ethanol ingestion on fatty acid oxidation by hepatic mitochondria. (1975) (85)
- Comparison of the ability of ferric complexes to catalyze microsomal chemiluminescence, lipid peroxidation, and hydroxyl radical generation. (1988) (82)
- Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. (2006) (81)
- CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells. (2010) (81)
- Chemical evidence for production of hydroxyl radicals during microsomal electron transfer. (1979) (80)
- Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury. (2010) (79)
- Increased Expression of Cytochrome P450 2E1 Induces Heme Oxygenase-1 through ERK MAPK Pathway* (2003) (75)
- Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine. (1983) (75)
- Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole. (2005) (75)
- Overexpression of CYP2E1 in Mitochondria Sensitizes HepG2 Cells to the Toxicity Caused by Depletion of Glutathione* (2006) (74)
- Characterization of shuttle mechanisms for the transport of reducing equivalents into mitochondria. (1973) (74)
- CYP 2 E 1 and Oxidative Liver Injury by Alcohol (2008) (74)
- Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK☆ (2013) (73)
- Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions. (1978) (72)
- Cytokines in alcoholic liver disease (2012) (72)
- Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. (2012) (72)
- Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide. (1997) (72)
- Effects of ethanol and fat on the transport of reducing equivalents into rat liver mitochondria. (1973) (72)
- Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals. (1988) (71)
- Molecular injury to mitochondria produced by ethanol and acetaldehyde. (1975) (70)
- Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations. (2004) (68)
- Characterization and identification of a pyrazole-inducible form of cytochrome P-450. (1988) (68)
- NADPH-dependent production of oxy radicals by purified components of the rat liver mixed function oxidase system. II. Role in microsomal oxidation of ethanol. (1983) (68)
- Overexpression of Catalase in the Mitochondrial or Cytosolic Compartment Increases Sensitivity of HepG2 Cells to Tumor Necrosis Factor-α-induced Apoptosis* (2000) (66)
- Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1. (2006) (66)
- CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury (2005) (65)
- Iron and CYP2E1-dependent oxidative stress and toxicity. (2003) (65)
- Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. (1997) (64)
- Increased oxygen radical‐dependent inactivation of metabolic enzymes by liver microsomes after chronic ethanol consumption (1988) (64)
- Oxidative demethylation of t-butyl alcohol by rat liver microsomes. (1980) (62)
- Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde. (1976) (62)
- Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. (2013) (60)
- Adenovirus-mediated Overexpression of Catalase in the Cytosolic or Mitochondrial Compartment Protects against Cytochrome P450 2E1-dependent Toxicity in HepG2 Cells* (2001) (60)
- Inactivation and degradation of human cytochrome P4502E1 by CCl4 in a transfected HepG2 cell line. (1995) (59)
- Hydroxyl radical generation by microsomes after chronic ethanol consumption. (1987) (59)
- Increased Cytotoxicity of 3-Morpholinosydnonimine to HepG2 Cells in the Presence of Superoxide Dismutase (1995) (59)
- Metabolism of carbon tetrachloride to trichloromethyl radical: An ESR and HPLC-EC study. (1999) (59)
- CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases (2011) (58)
- Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity. (2004) (58)
- The generation of hydroxyl and alkoxyl radicals from the interaction of ferrous bipyridyl with peroxides. (1983) (58)
- CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90. (2000) (57)
- Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice (2005) (57)
- Role of p38 MAPK in CYP2E1-dependent Arachidonic Acid Toxicity* (2003) (56)
- Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole. (1986) (56)
- Effect of acetaldehyde on fatty acid oxidation and ketogenesis by hepatic mitochondria. (1975) (56)
- Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. (2004) (56)
- Transfer and reoxidation of reducing equivalents as the rate-limiting steps in the oxidation of ethanol by liver cells isolated from fed and fasted rats. (1977) (56)
- Increased oxidation of p-nitrophenol and aniline by intact hepatocytes isolated from pyrazole-treated rats. (1990) (55)
- Nrf2 and antioxidant defense against CYP2E1 toxicity (2009) (55)
- Development and properties of HepG2 cells that constitutively express CYP2E1. (2008) (54)
- S-Adenosylmethionine Blocks Collagen I Production by Preventing Transforming Growth Factor-β Induction of the COL1A2 Promoter* (2005) (53)
- NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species. (1999) (53)
- Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1 (2004) (53)
- Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol. (1983) (53)
- Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway. (2012) (52)
- Abnormal serum transaminase levels in patients with hemophilia A. (1982) (52)
- Ethanol oxidation by hydroxyl radicals: role of iron chelates, superoxide, and hydrogen peroxide. (1985) (52)
- Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha–induced liver injury through activation of mitogen‐activated protein kinases in mice (2008) (52)
- Microsomal generation of reactive oxygen species and their possible role in alcohol hepatotoxicity. (1991) (51)
- Characterization of a nonhepatic alcohol dehydrogenase from rat hepatocellular carcinoma and stomach. (1975) (51)
- The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin. (2007) (51)
- Cytochrome P450s and Alcoholic Liver Disease. (2018) (51)
- Alcoholic liver disease and apoptosis. (2001) (50)
- CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction (2010) (50)
- Autophagy Protects against CYP2E1/Chronic Ethanol-Induced Hepatotoxicity (2015) (49)
- Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. (2002) (49)
- Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo. (2013) (48)
- CYP2E1-Dependent Toxicity and Up-Regulation of Antioxidant Genes (2001) (48)
- Preparation and properties of S-nitroso-L-cysteine ethyl ester, an intracellular nitrosating agent. (2001) (48)
- Generation of reactive oxygen intermediates by human liver microsomes in the presence of NADPH or NADH. (1994) (48)
- Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice. (2006) (47)
- Ethanol increases content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line. (1994) (47)
- Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole. (1992) (47)
- Cycloheximide Protects HepG2 Cells from Serum Withdrawal-Induced Apoptosis by Decreasing p53 and Phosphorylated p53 Levels (2006) (47)
- [68] Microsomal oxidant radical production and ethanol oxidation (1984) (47)
- NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents. (1991) (46)
- Effect of thiourea on microsomal oxidation of alcohols and associated microsomal functions. (1979) (46)
- FORUM Mechanisms of Hepatotoxicity (2002) (46)
- DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment. (1994) (46)
- Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells overexpressing human cytochrome P-4502E1. (1998) (45)
- Interaction of 1-Hydroxyethyl Radical With Glutathione, Ascorbic Acid and α-Tocopherol (1998) (45)
- Mitochondrial alterations in livers of Sod1-/- mice fed alcohol. (2007) (44)
- Role of the proteasome in ethanol-induced liver pathology. (2007) (44)
- Ethanol Induction of CYP2A5: Permissive Role for CYP2E1 (2011) (44)
- Ferritin stimulation of hydroxyl radical production by rat liver nuclei. (1994) (43)
- Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine. (2005) (43)
- Glutathione Depletion in CYP2E1-Expressing Liver Cells Induces Toxicity Due to the Activation of p38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-κB DNA Binding Activity (2004) (43)
- Inhibition of rat liver microsomal lipid peroxidation by boldine. (1992) (43)
- Role of cytochrome P-450 in the stimulation of microsomal production of reactive oxygen species by ferritin. (1996) (42)
- Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity (2004) (41)
- Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes. (2001) (41)
- Role of Calcium and Calcium-activated Proteases in CYP2E1-dependent Toxicity in HEPG2 Cells* (2002) (41)
- Oxidative decarboxylation of benzoate to carbon dioxide by rat liver microsomes: a probe for oxygen radical production during microsomal electron transfer. (1982) (41)
- Interaction of nitric oxide with 2-thio-5-nitrobenzoic acid: implications for the determination of free sulfhydryl groups by Ellman's reagent. (1997) (41)
- Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity. (2003) (41)
- Role of hydroxyl radicals in the iron-ethylenediaminetetraacetic acid mediated stimulation of microsomal oxidation of ethanol. (1980) (40)
- Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-kappaB. (1997) (40)
- Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1. (2006) (39)
- Transcription Factor Nrf2 Protects HepG2 Cells against CYP2E1 plus Arachidonic Acid-dependent Toxicity* (2006) (39)
- Thiol oxidation and cytochrome P450-dependent metabolism of CCl4 triggers Ca2+ release from liver microsomes. (1996) (39)
- Chemiluminescence from acetaldehyde oxidation by xanthine oxidase involves generation of and interactions with hydroxyl radicals. (1989) (38)
- Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency. (2008) (38)
- Role of apoptosis in alcoholic liver injury. (2003) (38)
- Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes. (1982) (37)
- Generation of reactive oxygen species by the redox cycling of nitroprusside. (1996) (37)
- 1-Hydroxyethyl radical formation during NADPH- and NADH-dependent oxidation of ethanol by human liver microsomes. (1996) (37)
- CYP2E1-dependent toxicity and up-regulation of antioxidant genes. (2001) (36)
- Ethanol oxidation by isolated hepatocytes from ethanol-treated and control rats; factors contributing to the metabolic adaptation after chronic ethanol consumption. (1978) (36)
- Production of nitric oxide and other iron-containing metabolites during the reductive metabolism of nitroprusside by microsomes and by thiols. (1995) (35)
- Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity. (2001) (35)
- The effect of EDTA and iron on the oxidation of hydroxyl radical scavenging agents and ethanol by rat liver microsomes. (1983) (34)
- Oxidation of glycerol to formaldehyde by rat liver microsomes. (1988) (34)
- Increased Sp1-dependent Transactivation of theLAMγ1 Promoter in Hepatic Stellate Cells Co-cultured with HepG2 Cells Overexpressing Cytochrome P450 2E1* (2003) (34)
- Effect of chronic ethanol consumption and acetaldehyde on partial reactions of oxidative phosphorylation and CO2 production from citric acid cycle intermediates. (1976) (34)
- Fatty acid oxidation, substrate shuttles, and activity of the citric acid cycle in hepatocellular carcinomas of varying differentiation. (1976) (34)
- Increased microsomal oxidation of ethanol by cytochrome P-450 and hydroxyl radical-dependent pathways after chronic ethanol consumption. (1984) (34)
- ESR and HPLC-EC analysis of the interaction of hydroxyl radical with DMSO: rapid reduction and quantification of POBN and PBN nitroxides. (1999) (34)
- Geldanamycin, an Inhibitor of Hsp90, Potentiates Cytochrome P4502E1-Mediated Toxicity in HepG2 Cells (2006) (34)
- Increased NADPH-dependent chemiluminescence by microsomes after chronic ethanol consumption. (1988) (34)
- Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells (1998) (33)
- Cytochrome P450 2E1 responsiveness in the promoter of glutamate‐cysteine ligase catalytic subunit (2003) (33)
- Increased microsomal oxidation of alcohols after pyrazole treatment and its similarities to the induction by ethanol consumption. (1984) (33)
- Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1. (2006) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Prevention of microsomal production of hydroxyl radicals, but not lipid peroxidation, by the glutathione-glutathione peroxidase system. (1986) (33)
- Nrf2 and antioxidant defense against CYP2E1 toxicity. (2013) (32)
- Factors contributing to the adaptive increase in ethanol metabolism due to chronic consumption of ethanol. (1977) (32)
- ESR studies on the production of reactive oxygen intermediates by rat liver microsomes in the presence of NADPH or NADH. (1993) (32)
- Expression of a catalytically active human cytochrome P-4502E1 in Escherichia coli. (1992) (32)
- Mitochondrial permeability transition induced by 1-hydroxyethyl radical. (2000) (32)
- Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction (2014) (31)
- Boldine prevents human liver microsomal lipid peroxidation and inactivation of cytochrome P4502E1. (1995) (31)
- Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes. (1982) (30)
- Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1. (2007) (30)
- Renal cell carcinoma in polycystic kidneys: case report and review of literature. (1980) (30)
- Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and -independent pathways. (2007) (30)
- The Effect of CYP2E1-Dependent Oxidant Stress on Activity of Proteasomes in HepG2 Cells (2005) (30)
- Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria. (2002) (29)
- Increased sensitivity of the microsomal oxidation of ethanol to inhibition by pyrazole and 4-methylpyrazole after chronic ethanol treatment. (1987) (29)
- Role of cytochrome P-450 IIE1 and catalase in the oxidation of acetonitrile to cyanide. (1989) (28)
- Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury. (1976) (28)
- Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems. (2001) (28)
- Induction of liver cytochrome P4502E1 by pyrazole and 4-methylpyrazole in neonatal rats. (1993) (28)
- Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells (2017) (28)
- Herpes simplex encephalitis in a patient with lymphoma. Relapse following acyclovir therapy. (1988) (28)
- Effect of chronic clofibrate administration on mitochondrial fatty acid oxidation. (1976) (28)
- Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism. (2001) (28)
- S-Adenosyl-l-methionine Attenuates Hepatotoxicity Induced by Agonistic Jo2 Fas Antibody following CYP2E1 Induction in Mice (2006) (28)
- The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference (2015) (27)
- A correlation between hydroxyl radical generation and ethanol oxidation by liver, lung and kidney microsomes. (1982) (27)
- Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1. (2002) (27)
- Binding of iron and copper to bovine heart mitochondria. I. Quantitative aspects and stability. (1972) (26)
- Stereochemical studies on the cytochrome P-450 and hydroxyl radical dependent pathways of 2-butanol oxidation by microsomes from chow-fed, phenobarbital-treated, and ethanol-treated rats. (1984) (26)
- NADPH- and NADH-dependent oxygen radical generation by rat liver nuclei in the presence of redox cycling agents and iron. (1990) (26)
- CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment (2012) (26)
- NADH-dependent microsomal interaction with ferric complexes and production of reactive oxygen intermediates. (1989) (26)
- Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells. (2011) (25)
- Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway. (2007) (25)
- Decomposition of Sodium Trioxodinitrate (Angeli's Salt) To Hydroxyl Radical: An ESR Spin-Trapping Study (1999) (25)
- Fractionation of liver microsomes with polyethylene glycol and purification of NADH-cytochrome b5 oxidoreductase and cytochrome b5. (1994) (25)
- The effect of cyanamide on acetaldehyde oxidation by isolated rat liver mitochondria and on the inhibition of pyruvate oxidation by acetaldehyde. (2008) (25)
- The effect of chronic ethanol consumption on NADH- and NADPH-dependent generation of reactive oxygen intermediates by isolated rat liver nuclei. (1992) (25)
- Effect of chronic ethanol consumption on microsomal lipid peroxidation (1986) (25)
- The oxidation of acetaldehyde by isolated mitochondria from various organs of the rat and hepatocellular carcinoma. (1977) (25)
- Effect of cyanamide on the metabolism of ethanol and acetaldehyde and on gluconeogenesis by isolated rat hepatocytes. (1981) (25)
- Dominant inheritance of hemophilia A in three generations of women. (1975) (24)
- Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury. (2015) (24)
- Increased NADH-dependent production of reactive oxygen intermediates by microsomes after chronic ethanol consumption: comparisons with NADPH. (1992) (24)
- Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes. (2007) (24)
- Microsomal interactions between iron, paraquat, and menadione: effect on hydroxyl radical production and alcohol oxidation. (1985) (23)
- Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro (2015) (23)
- Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells (2003) (22)
- Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells. (1996) (22)
- Glycerol increases content and activity of human cytochrome P-4502E1 in a transduced HepG2 cell line by protein stabilization. (1997) (22)
- ESR and HPLC-EC analysis of ethanol oxidation to 1-hydroxyethyl radical: rapid reduction and quantification of POBN and PBN nitroxides. (1998) (22)
- Effects of clofibrate on mitochondrial function. (1974) (22)
- Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1. (1990) (22)
- Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. (2006) (21)
- Role of Phosphatidylinositol 3-Kinase/AKT as a Survival Pathway against CYP2E1-Dependent Toxicity (2006) (21)
- Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents. (1990) (21)
- Role of iron, hydrogen peroxide and reactive oxygen species in microsomal oxidation of glycerol to formaldehyde. (1991) (21)
- Role of Phospholipase A2 Activation and Calcium in CYP2E1-dependent Toxicity in HepG2 Cells* (2003) (21)
- Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury. (2010) (21)
- Binding of iron and copper to bovine heart mitochondria. II. Effect of mitochondrial metabolism. (1972) (21)
- Interaction of 1-hydroxyethyl radical with antioxidant enzymes. (1999) (21)
- Oxidation of isopropanol by rat liver microsomes: possible role of hydroxyl radicals. (1981) (21)
- Stereospecificity of ethanol oxidation. (1973) (20)
- Detection of Genetic Variants of Haemophilia B with an Immunosorbent Technique (1973) (20)
- Increased content of cytochrome P-450 and 4-methylpyrazole binding spectrum after 4-methylpyrazole treatment. (1985) (20)
- Role of cytochrome b5 in NADH-dependent microsomal reduction of ferric complexes, lipid peroxidation, and hydrogen peroxide generation. (1995) (20)
- Production of hydroxyl radicals and their role in the oxidation of ethanol by a reconstituted microsomal system containing cytochrome P-450 purified from phenobarbital-treated rats. (1979) (20)
- Effect of phenobarbital and 3-methylcholanthrene treatment on NADPH- and NADH-dependent production of reactive oxygen intermediates by rat liver nuclei. (1992) (20)
- Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function. (1974) (20)
- Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney. (1994) (20)
- Interaction of ferric complexes with NADH-cytochrome b5 reductase and cytochrome b5: lipid peroxidation, H2O2 generation, and ferric reduction. (1996) (20)
- Increased catalytic activity of cytochrome P-450IIE1 in pericentral hepatocytes compared to periportal hepatocytes isolated from pyrazole-treated rats. (1991) (20)
- Oxidation of ethylene glycol to formaldehyde by rat liver microsomes. Role of cytochrome P-450 and reactive oxygen species. (1991) (20)
- Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria. (1976) (19)
- Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole. (1986) (19)
- Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis. (2017) (19)
- HBx Inhibits CYP2E1 Gene Expression via Downregulating HNF4α in Human Hepatoma Cells (2014) (19)
- Ferritin stimulation of lipid peroxidation by microsomes after chronic ethanol treatment: role of cytochrome P4502E1. (1996) (19)
- Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice. (2009) (19)
- The effect of pargyline on the metabolism of ethanol and acetaldehyde by isolated rat liver cells. (1979) (19)
- Combined effects of streptozotocin-induced diabetes plus 4-methylpyrazole treatment on rat liver cytochrome P4502E1. (1993) (18)
- S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. (2007) (18)
- Expression of cytochrome P4502E1 in rat fetal hepatocyte culture. (1996) (18)
- Effect of pyridine on the expression of cytochrome P450 isozymes in primary rat hepatocyte culture (1997) (18)
- Inhibition of the oxidation of acetaldehyde and formaldehyde by hepatocytes and mitochondria by crotonaldehyde. (1984) (18)
- Role of cytochrome P450 in the oxidation of glycerol by reconstituted systems and microsomes (1992) (18)
- Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. (2009) (18)
- The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. (2004) (18)
- Oxidation of the alcohol dehydrogenase inhibitor pyrazole to 4-hydroxypyrazole by microsomes. Effect of cytochrome P-450 inducing agents. (1987) (18)
- Effect of chronic ethanol ingestion on mitochondrial permeability and the transport of reducing equivalents. (1972) (18)
- Interactions between paraquat and ferric complexes in the microsomal generation of oxygen radicals. (1989) (18)
- Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1. (2002) (17)
- Oxidation of glycerol to formaldehyde by microsomes: are glycerol radicals produced in the reaction pathway? (1994) (17)
- Interaction of pyrazole and 4-methylpyrazole with hepatic microsomes: effect on cytochrome P-450 content, microsomal oxidation of alcohols, and binding spectra. (1985) (17)
- Interaction of ferric complexes with rat liver nuclei to catalyze NADH-and NADPH-Dependent production of oxygen radicals. (1989) (17)
- Stimulation by paraquat of microsomal and cytochrome P-450-dependent oxidation of glycerol to formaldehyde. (1993) (17)
- Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver. (2013) (17)
- Ethanol consumption by the nursing mother induces cytochrome P-4502E1 in neonatal rat liver. (1993) (16)
- Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450. (2006) (15)
- Generation of reactive oxygen species and reduction of ferric chelates by microsomes in the presence of a reconstituted system containing ethanol, NAD+ and alcohol dehydrogenase. (1990) (15)
- Stimulation of microsomal chemiluminescence by ferritin. (1993) (15)
- Inhibition of ferritin-stimulated microsomal production of reactive oxygen intermediates by nitric oxide. (1997) (15)
- An ESR and HPLC-EC assay for the detection of alkyl radicals. (2001) (15)
- Organic hydroperoxide-dependent oxidation of ethanol by microsomes: lack of a role for free hydroxyl radicals. (1983) (15)
- Increased oxidation of dimethylnitrosamine in pericentral microsomes after pyrazole induction of cytochrome P-4502E1. (1991) (14)
- Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. (2007) (14)
- Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. (2005) (14)
- Inhibition of the peroxidatic activity of catalase towards alcohols by the aldehyde dehydrogenase inhibitor cyanamide. (1985) (14)
- Sensitivity to acetaldehyde of pyruvate oxidation by mitochondria from liver, kidney, brain and muscle (1977) (13)
- Effect of ethanol and metabolic substrates on the oxidation of aminopyrine, formaldehyde and formate by isolated hepatocytes. (1983) (13)
- A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. (1997) (13)
- Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity. (2006) (13)
- Cytochrome P450 and Oxidative Stress in the Liver (2017) (13)
- Cytochrome P 450 2 E 1-derived Reactive Oxygen Species Mediate Paracrine Stimulation of Collagen I Protein Synthesis by Hepatic Stellate Cells * (2002) (13)
- Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA). (1986) (12)
- Increased oxidation of ethylene glycol to formaldehyde by microsomes after ethanol treatment: role of oxygen radicals and cytochrome P450. (1995) (12)
- Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice. (2015) (12)
- Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice. (2009) (12)
- Effect of acetaldehyde and cyanamide on the metabolism of formaldehyde by hepatocytes, mitochondria, and soluble supernatant from rat liver. (1984) (12)
- Multifactorial Comparative Proteomic Study of Cytochrome P450 2E1 Function in Chronic Alcohol Administration (2014) (12)
- Ethanol Induction of CYP 2 A 5 : Permissive Role for CYP 2 E 1 (2011) (12)
- Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl maleate and phorone in vivo and in vitro. Implications for formaldehyde metabolism. (1986) (12)
- Sensitivity of the rat liver microsomal oxidation of pyrazole to antibody raised against the ethanol-inducible rabbit liver cytochrome P-450 isozyme. (1989) (11)
- Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX. (1985) (11)
- S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice. (2008) (11)
- Protein Kinase C Signaling as a Survival Pathway against CYP2E1-Derived Oxidative Stress and Toxicity in HepG2 Cells (2005) (11)
- Evidence for two ethanol oxidizing pathways in reconstituted mixed-function oxidase systems (1983) (11)
- Differential effects of acetate on palmitate and octanoate oxidation: segregation of acetyl CoA pools. (1975) (11)
- Temperature dependence of the microsomal oxidation of ethanol by cytochrome P450 and hydroxyl radical-dependent reactions. (1989) (11)
- Redox-cycling of iron ions triggers calcium release from liver microsomes. (1998) (11)
- Requirement for iron for the production of hydroxyl radicals by rat liver quinone reductase. (1993) (11)
- Alcohol Upregulation of CYP2A5: Role of Reactive Oxygen Species. (2016) (10)
- Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. (2008) (10)
- CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells. (2009) (10)
- Binding of iron and copper to bovine heart mitochondria. 3. Role of mitochondrial phospholipids and thiols. (1972) (10)
- Low-temperature induction of respiratory deficiency in yeast mutants. (1973) (10)
- Cycloheximide Protects HepG 2 Cells from Serum Withdrawal-Induced Apoptosis by Decreasing p 53 and Phosphorylated p 53 Levels (2006) (10)
- Role of Cytochrome P450 and Oxidative Stress in Alcohol-Induced Liver Injury (2017) (10)
- Microsomal oxidant radical production and ethanol oxidation. (1984) (10)
- CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model (2019) (10)
- Increased microsomal interaction with iron and oxygen radical generation after chronic acetone treatment. (1988) (9)
- Ferritin-dependent inactivation of microsomal glucose-6-phosphatase. (1994) (9)
- Immunoblastic lymphadenopathy presenting as respiratory insufficiency. (1977) (9)
- Complex-formation and reduction of ferric iron by 2-oxo-4-thiomethylbutyric acid, and the production of hydroxyl radicals. (1986) (9)
- Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5. (2018) (9)
- Kinetic properties of alcohol dehydrogenase in hepatocellular carcinoma and normal tissues of rat. (1976) (9)
- Oxidative Stress and Cytotoxicity Induced by Ferric-Nitrilotriacetate in HepG 2 Cells That Express Cytochrome P 450 2 E 1 (1998) (9)
- Metabolites of acetaminophen trigger Ca2+ release from liver microsomes. (1999) (9)
- Inhibition of the oxidation of hydroxyl radical scavenging agents after alkaline phosphatase treatment of rat liver microsomes. (1991) (9)
- CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity (2014) (9)
- Increased production of hydroxyl radical by pericentral microsomes compared to periportal microsomes after pyrazole induction of cytochrome P4502E1. (1995) (9)
- Oxygen radical generation by microsomes: role of iron and implications for alcohol metabolism and toxicity. (1989) (8)
- The effect of acetaldehyde on gluconeogenesis from xylitol, sorbitol, and fructose by isolated rat liver cells. (1979) (8)
- Structural determinants for alcohol substrates to be oxidized to formaldehyde by rat liver microsomes. (1992) (8)
- Regulation of pathways of alcohol metabolism by the liver. (1980) (8)
- ORGANELLE PATHOLOGY OF ALCOHOL-INDUCED HEPATIC INJURY (1977) (8)
- Comparison of the interaction of pyrazole and its metabolite 4-hydroxypyrazole with rat liver microsomes. (1990) (7)
- Inhibition of mitochondrial aldehyde dehydrogenase and acetaldehyde oxidation by the glutathione-depleting agents diethylmaleate and phorone. (1985) (7)
- Stimulation of NADH-dependent microsomal DNA strand cleavage by rifamycin SV. (1995) (7)
- CYP 2 E 1 Sensitizes the Liver to LPS-and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNKMitogen-Activated Kinases (2014) (7)
- Role of hydroxyl radicals in microsomal oxidation of alcohols. (1980) (6)
- The Effect of CYP 2 E 1-Dependent Oxidant Stress on Activity of Proteasomes in HepG 2 Cells (2005) (6)
- Oxidation of pyrazole to 4-hydroxypyrazole by intact rat hepatocytes. (1988) (6)
- Evaluation of the role of acetaldehyde in the actions of ethanol on gluconeogenesis by comparison with the effects of crotonol and crotonaldehyde. (1982) (6)
- Evaluation of a role of acetaldehyde in the mechanism of inhibition of p-nitroanisole O-demethylation in isolated hepatocytes by ethanol. (1982) (6)
- Geldanamycin , an Inhibitor of Hsp 90 , Potentiates Cytochrome P 4502 E 1-Mediated Toxicity in HepG 2 Cells (2006) (5)
- Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice. (2019) (5)
- Chemiluminescence studies on the generation of oxygen radicals from the interaction of NADPH-cytochrome P-450 reductase with iron. (1987) (5)
- Stimulation of microsomal production of reactive oxygen intermediates by rifamycin SV: effect of ferric complexes and comparisons between NADPH and NADH. (1992) (4)
- S-Adenosyl-L-methionine Attenuates Hepatotoxicity Induced by Agonistic Jo 2 Fas Antibody following CYP 2 E 1 Induction in Mice (2006) (4)
- CYP2E1- and TNFalpha/LPS-Induced Oxidative Stress and MAPK Signaling Pathways in Alcoholic Liver Disease (2015) (4)
- The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats. (1992) (4)
- High fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: A new model for steatohepatitis-associated fibrosis. (2020) (4)
- Production of 4-hydroxypyrazole from the interaction of the alcohol dehydrogenase inhibitor pyrazole with hydroxyl radical. (1987) (4)
- Oxidative Stress , JNK and Autophagy in Acute Alcohol-induced Fatty Liver (2013) (4)
- CYP2E1 Potentiates Ethanol-induction of Hypoxia and HIF-1 α in vivo (2013) (4)
- Ethanol upregulates pro-fibrogenic connective tissue growth factor (CTGF) gene expression in HepG2 cells via cytochrome P450 2E1-mediated ethanol oxidation (2004) (4)
- Oxygen-concentration dependence of microsomal chemiluminescence. (1989) (3)
- Formation of an Iron‐Methiolbutyric Acid (FeKTBA) Complex: Interaction with Hydrogen Peroxide and Production of Oxygen Radicals (1984) (3)
- Inhibition of CO2 production from aminopyrine or methanol by cyanamide or crotonaldehyde and the role of mitochondrial aldehyde dehydrogenase in formaldehyde oxidation. (1986) (3)
- Glutathione Depletion in CYP 2 E 1-Expressing Liver Cells Induces Toxicity Due to the Activation of p 38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-B DNA Binding Activity (2004) (3)
- Role of citrate in stimulation of the fatty acid shuttle for the transport of reducing equivalents into mitochondria. (1973) (3)
- Ethylene production from alpha-keto-4-thiomethylbutyric acid by isolated rat liver cells, suspension medium, and perfusates in the absence and presence of iron. (1985) (3)
- Interaction of 1-hydroxyethyl radical with glutathione, ascorbic acid and alpha-tocopherol. (1998) (3)
- THE PRODUCTION OF HYDROXYL RADICALS BY RAT LIVER MICROSOMES (1980) (2)
- The effect of calcium on the oxidation of acetaldehyde by rat liver mitochondria. (1978) (2)
- Vitamin E Prevents NADPH‐Dependent but not NADH‐Dependent Chemoluminescence by Isolated Rat Liver Nuclei (1989) (2)
- Chapter 2 Nrf 2 and Antioxidant Defense Against CYP 2 E 1 Toxicity (2018) (2)
- Ethanol-induction of Cytochrome P 450 2 A 5 : Permissive Role for CYP 2 E 1 (2010) (2)
- 370 S-adenosyl--methionine represses the responsiveness of the alpha 2(I) collagen promoter to CCL in transgenic mice (2003) (1)
- Pathways of Metabolism of Formaldehyde Produced from the Oxidation of Aminopyrine by Intact Rat Hepatocytes (1987) (1)
- ETHANOL-OXIDIZING ENZYMES IN TRANSPLANTABLE HEPATOCELLULAR CARCINOMS (1977) (1)
- Threshold for Antiproliferative and Proapoptotic Activity of Taxol in HepG2 Cells Expressing Human CYP3A4: Effect of P-Glycoprotein Transporters (2003) (1)
- Oxygen radical production by human cyt. P450 (1993) (1)
- Increased Content of Cytochrome P‐450 and Microsomal Alcohol Oxidation after 4‐Methylpyrazole Treatment (1986) (1)
- A comparison of the effects of ethanol and acetaldehyde on glucose production from various precursors by isolated rat liver cells. (1979) (1)
- THE OXIDATION OF ACETALDEHYDE BY RAT HEPATIC, NON-HEPATIC AND TUMOR MITOCHONDRIA (1977) (1)
- New England Hemophilia Center: A Comprehensive Home Care Model (1982) (1)
- Microsomal Lipid Peroxidation and Hydroxyl Radical Production Involve Different Oxygen Radical Species (1987) (0)
- Rifamycin SV stimulates ·OH-mediated DNA strand cleavage by microsomes in the presence of NADH and catalytic iron (1993) (0)
- Iron and Ethanol-Induced Tissue Damage: Generation of Reactive Oxygen Intermediates and Possible Mechanisms for Their Role in Alcohol Liver Toxicity (2018) (0)
- Editorial: New Insights into Mechanisms of Alcohol-Induced Fatty Liver. (2017) (0)
- Effect of inhibitors and substrates on oxygen radical production by cytochrome P450 (1993) (0)
- In‐Vivo and In‐Vitro Inhibition of the Low Km Aldehyde Dehydrogenase by Diethylmaleate and Phorone (1987) (0)
- Subject Index Vol. 28, 2010 (2011) (0)
- Iron stimulation of chemiluminescence by microsomes and purified NADPH-cytochrome P-450 reductase (1987) (0)
- Contents Vol. 28, 2010 (2011) (0)
- First Pass Metabolism of Alcohol in the Stomach (2012) (0)
- Increased cleavage of ethylene glycol to formaldehyde by oxidants produced from cytochrome P4502E1 (1993) (0)
- Thioredoxin is Critical in Protecting HepG2 Cells from CYP2E1induced Oxidative Stress (2010) (0)
- Bleeding diatheses in the orthopedic patient. (1978) (0)
- Protein Kinase C Signaling as a Survival Pathway against CYP 2 E 1-Derived Oxidative Stress and Toxicity in HepG 2 Cells (2005) (0)
- in Three Generations of Women (2017) (0)
- Chapter 24 – Cytochrome P4502E1, Oxidative Stress, JNK, and Autophagy in Acute Alcohol-Induced Fatty Liver (2014) (0)
- The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference (2015) (0)
- Bioenergetics Changes Induced by CYP2E1 in HepG2 cells (2010) (0)
- ROLE OF INTRACELLULAR CALCIUM AND PHOSPHOLIPASE A2 IN ARACHIDONIC ACID-INDUCED TOXICITY IN LIVER CELLS (2008) (0)
- Fatty Acid Oxidation , Substrate Shuttles , and Activity of the Citric Acid Cycle in Hepatocellular Carcinomas of Varying Differentiation 1 (2006) (0)
- Introduction to the Symposium (1998) (0)
- JPET #102921 1 ROLE OF PI3 KINASE/AKT AS A SURVIVAL PATHWAY AGAINST CYP2E1 DEPENDENT TOXICITY (2006) (0)
- ROS Role of Cytochrome P 450 and Oxidative Stress in Alcohol-Induced Liver Injury (2017) (0)
- Use of transduced cell lines in studies on alcohol metabolism and toxicity. Introduction to the symposium. (1998) (0)
- Diagnosis and treatment of intravascular coagulation. (1973) (0)
- Cytokines in alcoholic liver disease (2012) (0)
- Purification of the pyrazole-inducible cytochrome P-450 isozyme (1987) (0)
- The Effects of Chronic Ethanol Consumption and Acetaldehyde on Hepatic Mitochondria (1976) (0)
- Microsomal Interactions between Iron, Paraquat, and Menadione on Hydroxyl Radical Formation, Alcohol Oxidation, and Drug Metabolism (1986) (0)
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