Atsushi Ichikawa

Q: What Schools Are Affiliated With Atsushi Ichikawa

Atsushi Ichikawa is affiliated with the following schools: Kyoto University, Mukogawa Women's University

Atsushi Ichikawa's AcademicInfluence.com Rankings

Atsushi Ichikawa

Medical

#3452

World Rank

#3920

Historical Rank

Pharmacology

#434

World Rank

#487

Historical Rank

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Medical

Atsushi Ichikawa's Degrees

PhD Pharmacology University of Tokyo
Masters Pharmacology University of Tokyo
Bachelors Pharmacy University of Tokyo

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Atsushi Ichikawa's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor (1997) (778)
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3 (1998) (673)
Failure of parturition in mice lacking the prostaglandin F receptor. (1997) (599)
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity (1993) (534)
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype. (1993) (496)
The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. (2002) (473)
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2). (1999) (443)
The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. (2000) (398)
Molecular mechanisms of diverse actions of prostanoid receptors. (1995) (394)
Mice lacking histidine decarboxylase exhibit abnormal mast cells (2001) (390)
Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor. (1993) (377)
Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice. (1998) (305)
cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla. (1994) (264)
A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes (2003) (256)
Cloning and expression of a cDNA for mouse prostaglandin F receptor. (1994) (232)
Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins. (1993) (209)
Two Gs-coupled prostaglandin E receptor subtypes, EP2 and EP4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist. (1996) (207)
Impaired Bone Resorption to Prostaglandin E2 in Prostaglandin E Receptor EP4-knockout Mice* (2000) (205)
Distribution and function of prostanoid receptors: studies from knockout mice. (2000) (196)
Characterization of EP receptor subtypes responsible for prostaglandin E2‐induced pain responses by use of EP1 and EP3 receptor knockout mice (2001) (190)
Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3 (2005) (184)
Distribution of the messenger rna for the prostaglandin e receptor subtype ep3 in the mouse nervous system (1994) (182)
Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. (2001) (181)
Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase. (1993) (180)
Prostanoid receptor subtypes. (2002) (177)
Constitutively Active Gα12, Gα13, and Gαq Induce Rho-dependent Neurite Retraction through Different Signaling Pathways* (1998) (169)
Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors. (2003) (167)
The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and Northern blot analysis (1995) (165)
Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis. (1992) (158)
Identification of prostaglandin E receptor ‘EP2’ cloned from mastocytoma cells as EP4 subtype (1995) (154)
p160 RhoA-binding Kinase ROKα Induces Neurite Retraction* (1998) (150)
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype. (1992) (147)
Prostanoid receptors and their biological actions. (1993) (146)
Specific binding of glycyrrhetinic acid to the rat liver membrane. (1991) (134)
Distinct cellular localization of mRNAs for three subtypes of prostaglandin E receptor in kidney. (1994) (133)
Crucial Involvement of the EP4 Subtype of Prostaglandin E Receptor in Osteoclast Formation by Proinflammatory Cytokines and Lipopolysaccharide (2000) (131)
Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions. (1995) (130)
The Expression of Prostaglandin E Receptors EP2 and EP4 and Their Different Regulation by Lipopolysaccharide in C3H/HeN Peritoneal Macrophages1 (2001) (129)
Two isoforms of prostaglandin E receptor EP3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization. (1993) (128)
Prostaglandin F2α-induced Expression of 20α-Hydroxysteroid Dehydrogenase Involves the Transcription Factor NUR77* (2000) (126)
Prostaglandin receptors: advances in the study of EP3 receptor signaling. (2002) (124)
Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3). (1999) (122)
Reg gene expression is increased in rat gastric enterochromaffin-like cells following water immersion stress. (1996) (119)
Prostaglandin E receptor subtypes in mouse osteoblastic cell line. (1996) (116)
Two Isoforms of the Prostaglandin E Receptor EP3 Subtype Different in Agonist-independent Constitutive Activity (*) (1996) (112)
Increased Bleeding Tendency and Decreased Susceptibility to Thromboembolism in Mice Lacking the Prostaglandin E Receptor Subtype EP3 (2001) (107)
Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract. (1997) (106)
Characterization of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors in mouse macrophage-like cell line, J774.1. (1998) (99)
Prostaglandin E(2) receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. (2000) (99)
Cloning and expression of a cDNA for the human prostacyclin receptor (1994) (97)
Distribution of prostaglandin E receptors in the rat gastrointestinal tract. (1997) (93)
Characterization of the signal transduction of prostaglandin E receptor EP1 subtype in cDNA-transfected Chinese hamster ovary cells. (1995) (93)
Prostanoid EP4 receptor is involved in suppression of 3T3-L1 adipocyte differentiation. (2004) (91)
Impaired Bone Resorption by Lipopolysaccharide In Vivo in Mice Deficient in the Prostaglandin E Receptor EP4 Subtype (2000) (89)
Potential sites of prostaglandin actions in the periimplantation mouse uterus: differential expression and regulation of prostaglandin receptor genes. (1997) (89)
The amino acid sequence of a glutamic acid-rich protein from bovine retina as deduced from the cDNA sequence. (1991) (86)
Gastric acid secretion in L-histidine decarboxylase-deficient mice. (2002) (86)
Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors. (2000) (84)
cDNA‐derived amino acid sequence of L‐histidine decarboxylase from mouse mastocytoma P‐815 cells (1990) (83)
Immunocytochemical localization of prostaglandin EP3 receptor in the rat hypothalamus (1999) (83)
Expression of Messenger RNA for Prostaglandin E Receptor Subtypes EP4/EP2 and Cyclooxygenase Isozymes in Mouse Periovulatory Follicles and Oviducts During Superovulation1 (2003) (81)
Selective Coupling of Prostaglandin E Receptor EP3D to Gi and Gs through Interaction of α-Carboxylic Acid of Agonist and Arginine Residue of Seventh Transmembrane Domain (*) (1995) (76)
Antigen-independent Induction of Histamine Synthesis by Immunoglobulin E in Mouse Bone Marrow–derived Mast Cells (2002) (74)
Molecular aspects of the structures and functions of the prostaglandin E receptors. (1996) (74)
Major roles of prostanoid receptors IP and EP(3) in endotoxin-induced enhancement of pain perception. (2001) (72)
Prostaglandin E Receptor EP3 Subtype Induces Neurite Retraction via Small GTPase Rho* (1996) (71)
Plasma extravasation induced by dietary supplemented histamine in histamine‐free mice (2002) (71)
Expressions of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder: crucial role of arachidonate metabolism in tumor growth and progression. (2002) (70)
Histamine release induced from mast cells by active components of compound 48/80. (1985) (65)
Molecular cloning and expression of rat prostaglandin E receptor EP2 subtype. (1994) (65)
Opposite Regulation of Transepithelial Electrical Resistance and Paracellular Permeability by Rho in Madin-Darby Canine Kidney Cells* (1999) (64)
Prostaglandin E receptor EP3γ isoform, with mostly full constitutive Gi activity and agonist‐dependent Gs activity (1996) (62)
Uterine Expression of Prostaglandin H2 Synthase in Late Pregnancy and during Parturition in Prostaglandin F Receptor-Deficient Mice1. (2000) (61)
Timely interaction between prostaglandin and chemokine signaling is a prerequisite for successful fertilization (2008) (59)
Association of expression of mRNA encoding the PGF2 alpha receptor with luteal cell apoptosis in ovaries of pseudopregnant mice. (1997) (58)
Opposite coupling of prostaglandin E receptor EP3C with Gs and G(o). Stimulation of Gs and inhibition of G(o). (1993) (58)
Intracellular Localization of the 74- and 53-kDa Forms ofl-Histidine Decarboxylase in a Rat Basophilic/Mast Cell Line, RBL-2H3* (1998) (58)
Expression of messenger RNA for the prostaglandin D receptor in the leptomeninges of the mouse brain (1997) (57)
Purification and characterization of l-histidine decarboxylase from mouse mastocytoma P-815 cells. (1990) (57)
Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected Chinese hamster ovary cells. (1994) (56)
Roles of prostaglandin E receptors in mesangial cells under high-glucose conditions. (1999) (53)
Constitutively active Galpha12, Galpha13, and Galphaq induce Rho-dependent neurite retraction through different signaling pathways. (1998) (51)
Ca2+ influx‐mediated histamine synthesis and IL‐6 release in mast cells activated by monomeric IgE (2005) (50)
Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives. (2005) (50)
Contribution of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the inhibition by PGE2 of the LPS-induced TNFalpha-formation in Kupffer cells from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor in wild type Kupffer cells. (2002) (49)
Identification of a cis-Regulatory Element for Δ12-Prostaglandin J2-induced Expression of the Rat Heme Oxygenase Gene (*) (1995) (49)
The amino acid sequence of nucleoside diphosphate kinase I from spinach leaves, as deduced from the cDNA sequence. (1992) (47)
Prostaglandin E receptors. (1995) (46)
Uterine expression of prostaglandin H2 synthase in late pregnancy and during parturition in prostaglandin F receptor-deficient mice. (2000) (46)
cDNA cloning of a thromboxane A2 receptor from rat astrocytes. (1995) (44)
Crucial Role of Histamine for Regulation of Gastric Acid Secretion Ascertained by Histidine Decarboxylase-Knockout Mice (2003) (43)
Cloning and expression of a cDNA for rat prostaglandin F2α receptor (1994) (43)
Expression of L‐histidine decarboxylase in granules of elicited mouse polymorphonuclear leukocytes (2004) (43)
Recent advances in molecular pharmacology of the histamine systems: immune regulatory roles of histamine produced by leukocytes. (2006) (42)
Effect of cimetidine on intratumoral cytokine expression in an experimental tumor. (2001) (41)
Female reproduction in mice lacking the prostaglandin F receptor. Roles of prostaglandin and oxytocin receptors in parturition. (1998) (41)
Purification and characterization of nucleoside diphosphate kinase from spinach leaves. (1991) (40)
Identification of a prostacyclin receptor coupled to the adenylate cyclase system via a stimulatory GTP-binding protein in mouse mastocytoma P-815 cells. (1990) (40)
Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue‐type mast cells (2008) (39)
Prostaglandin F2alpha-induced expression of 20alpha-hydroxysteroid dehydrogenase involves the transcription factor NUR77. (2000) (39)
Induction of heme oxygenase by Δ12-prostaglandin J2 in porcine aortic endothelial cells (1992) (39)
Translocation of alpha subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells. (1992) (38)
Microarray evaluation of EP4 receptor-mediated prostaglandin E2 suppression of 3T3-L1 adipocyte differentiation. (2004) (38)
Inhibitory role of cyclic adenosine 3' 5'-monophosphate in histamine release from rat peritoneal mast cells in vitro. (1976) (37)
Effect of dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats (1988) (37)
Quantification of the number of EP3 receptors on a living CHO cell surface by the AFM. (2006) (37)
Role of Prostaglandin H2 Synthase 2 in Murine Parturition: Study on Ovariectomy-Induced Parturition in Prostaglandin F Receptor-Deficient Mice1 (2003) (37)
Signal transduction pathway regulating prostaglandin EP3 receptor-induced neurite retraction: requirement for two different tyrosine kinases. (1999) (36)
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP2 (gene targetingyfertilizationyovulationyprostanoidsygonadotropins) (1999) (36)
Activation of Histidine Decarboxylase through Post-translational Cleavage by Caspase-9 in a Mouse Mastocytoma P-815* (2007) (36)
Expression of l-Histidine Decarboxylase in Mouse Male Germ Cells* (2002) (36)
Interleukin 3 promotes histamine synthesis in hematopoietic progenitors by increasing histidine decarboxylase mRNA expression. (1993) (36)
The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein. (1994) (36)
Histamine synthesis is required for granule maturation in murine mast cells (2014) (35)
Structure and function of prostanoid receptors. (1993) (35)
Neuron-specific expression of cationic amino acid transporter 3 in the adult rat brain (1999) (35)
Two isoforms of prostaglandin EP3 receptor exhibiting constitutive activity and agonist-dependent activity in Rho-mediated stress fiber formation. (1997) (34)
Purification and properties of adenosine 3′,5′-monophosphate phosphodiesterase from baker's yeast (1974) (33)
Characterization of the gene for the mouse prostaglandin E receptor subtype EP2: tissue-specific initiation of transcription in the macrophage and the uterus. (1998) (33)
RhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly. (2009) (33)
Biological actions of δ12-prostaglandin J2 (1995) (33)
Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding. (1993) (33)
Involvement of cyclooxygenase-2 and EP3 prostaglandin receptor in acute herpetic but not postherpetic pain in mice (2005) (32)
Expression and characterization of recombinant mouse mastocytoma histidine decarboxylase. (1993) (32)
Localization of a cyclopentenone prostaglandin to the endoplasmic reticulum and induction of BiP mRNA. (1998) (32)
Possible coupling of prostaglandin E receptor EP(1) to TRP5 expressed in Xenopus laevis oocytes. (2002) (32)
Effect of cyclic 3',5'-monophosphate on edema and granuloma induced by carrageenin. (1972) (31)
7,7-Difluoroprostacyclin derivative, AFP-07, a highly selective and potent agonist for the prostacyclin receptor. (1997) (30)
Histidine Decarboxylase Expression in Mouse Mast Cell Line P815 Is Induced by Mouse Peritoneal Cavity Incubation* (1996) (30)
Molecular biology of histidine decarboxylase and prostaglandin receptors (2010) (30)
Enhancement by protein kinase C of prostacyclin receptor-mediated activation of adenylate cyclase through a calmodulin/myristoylated alanine-rich C kinase substrate (MARCKS) system in IC2 mast cells. (1993) (29)
Regulation of BiP Gene Expression by Cyclopentenone Prostaglandins through Unfolded Protein Response Element* (1996) (29)
Augmentation of receptor-mediated adenylyl cyclase activity by Gi-coupled prostaglandin receptor subtype EP3 in a Gbetagamma subunit-independent manner. (2002) (29)
Mouse mammary epithelial histamine system. (2003) (29)
Histidine decarboxylase deficiency in gene knockout mice elevates male sex steroid production. (2002) (28)
Mapping of the genes encoding mouse thromboxane A2 receptor and prostaglandin E receptor subtypes EP2 and EP3. (1994) (28)
Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype. (1997) (28)
Characterization of the mouse prostaglandin F receptor gene: a transgenic mouse study of a regulatory region that controls its expression in the stomach and kidney but not in the ovary (1997) (28)
Activation of heat shock transcription factors by delta 12-prostaglandin J2 and its inhibition by intracellular glutathione. (1993) (28)
Expression of prostaglandin E(2) receptor subtypes in mouse hair follicles. (2002) (28)
Degradation of the 74 kDa form of l‐histidine decarboxylase via the ubiquitin‐proteasome pathway in a rat basophilic/mast cell line (RBL‐2H3) (1997) (28)
Histamine H(2) receptor-mediated modulation of local cytokine expression in a mouse experimental tumor model. (2002) (26)
Identification and characterization of a novel progesterone receptor‐binding element in the mouse prostaglandin E receptor subtype EP2 gene (2003) (26)
Nucleotide sequence of the cDNA encoding nucleoside diphosphate kinase II from spinach leaves. (1993) (26)
'Distinct cellular localization' of the messenger ribonucleic acid for prostaglandin E receptor subtypes in the mouse uterus during pseudopregnancy. (1997) (26)
A third type of nucleoside diphosphate kinase from spinach leaves: purification, characterization and amino-acid sequence. (1995) (25)
Prostaglandin E2 Stimulates Granulocyte Colony-Stimulating Factor Production via the Prostanoid EP2 Receptor in Mouse Peritoneal Neutrophils 1 (2005) (25)
The effects of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on T-cell-related cytokine production in vitro and in vivo. (2006) (25)
Lack of histamine alters gastric mucosal morphology: comparison of histidine decarboxylase-deficient and mast cell-deficient mice. (2004) (25)
Copresence of prostaglandin EP2 and EP3 receptors on gastric enterochromaffin-like cell carcinoid in African rodents. (1995) (24)
An acute inflammation induced by inorganic pyrophosphate and adenosine triphosphate, and its inhibition by cyclic 3',5'-adenosine monophosphate. (1972) (24)
Membrane targeting and binding of the 74‐kDa form of mouse l‐histidine decarboxylase via its carboxyl‐terminal sequence (1998) (24)
Apoptosis and Related Proteins in Placenta of Intrauterine Fetal Death in Prostaglandin F Receptor-Deficient Mice1 (2003) (24)
Expression of apoptosis in placentae from mice lacking the prostaglandin F receptor. (2002) (24)
Functional evidence for interaction between prostaglandin EP3 and κ-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120 (2003) (24)
Accumulation of adenosine 3',5'-monophosphate induced by prostaglandin E1 binding to mastocytoma P-815 cells. (1981) (23)
Binding of active components of compound 48/80 to rat peritoneal mast cells. (1985) (22)
TEI-3356, a highly selective agonist for the prostaglandin EP3 receptor. (1994) (22)
Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase. (1995) (22)
Identification of the prostacyclin receptor by use of [15-3H1]19-(3-azidophenyl)-20-norisocarbacyclin, an irreversible specific photoaffinity probe. (1992) (22)
Two types of prostacyclin receptor coupling to stimulation of adenylate cyclase and phosphatidylinositol hydrolysis in a cultured mast cell line, BNu-2cl3 cells. (1993) (21)
Induction of Adherent Activity in Mastocytoma P-815 Cells by the Cooperation of Two Prostaglandin E2 Receptor Subtypes, EP3 and EP4* (2003) (21)
The key amino acid residue of prostaglandin EP3 receptor for governing G protein association and activation steps. (1999) (21)
Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7. (2003) (21)
Characterization of the prostaglandin E receptor expressed on a cultured mast cell line, BNu-2cl3. (1993) (21)
Involvement of CD44 in mast cell proliferation during terminal differentiation (2009) (21)
Release of serotonin from mast cells induced by N-(2-ethylhexyl)-3-hydroxybutyramide and catecholamine. (1977) (20)
Identification of multiple regulatory elements of human L-histidine decarboxylase gene. (1997) (20)
'Distinct Cellular Localization of the Messenger Ribonucleic Acid for Prostaglandin E Receptor Subtypes in the Mouse Uterus during Pseudopregnancy1. (1997) (20)
Synergistic effects of 12-O-tetradecanoylphorbol-13-acetate and dexamethasone on de novo synthesis of histidine decarboxylase in mouse mastocytoma P-815 cells. (1992) (20)
Purification and properties of L-histidine decarboxylase from mouse stomach. (1992) (20)
Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner. (2009) (19)
Prostaglandin E2 Attenuates Preoptic Expression of GABAA Receptors via EP3 Receptors* (2008) (19)
Involvement of protein kinase in Δ 12‐prostaglandin J2‐induced expression of rat heme oxygenase‐1 gene (1995) (19)
Critical Role of Protein Kinase C βII in Activation of Mast Cells by Monomeric IgE* (2005) (18)
Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors. (1996) (17)
Enhanced expression of the mouse L-histidine decarboxylase gene with a combination of dexamethasone and 12-O-tetradecanoylphorbol-13-acetate. (1993) (17)
Histamine deficiency suppresses murine haptoglobin production and modifies hepatic protein tyrosine phosphorylation (2001) (17)
Prostaglandin E receptors in bile ducts of hepatolithiasis patients and the pathobiological significance for cholangitis. (2003) (16)
A Cluster of Aromatic Amino Acids in the i2 Loop Plays a Key Role for Gs Coupling in Prostaglandin EP2 and EP3 Receptors* (2004) (16)
TEI-9063, a stable and highly specific prostacyclin analogue for the prostacyclin receptor in mastocytoma P-815 cells. (1991) (15)
Induction of a 31,000-dalton stress protein by prostaglandins D2 and J2 in porcine aortic endothelial cells. (1991) (15)
Functional domains essential for Gs activity in prostaglandin EP2 and EP3 receptors. (2003) (15)
Effect of the tridecamer of compound 48/80, a Ca2+-dependent histamine releaser, on phospholipid metabolism during the early stage of histamine release from rat mast cells. (1986) (14)
Effect of thyroid hormones on epinephrine-induced lipolysis in adipose tissue of rats. (1971) (14)
Functional role of car☐yl‐terminal tail of prostaglandin EP3 receptor in Gi coupling (1997) (14)
Major roles of prostanoid receptors IP and EP3 in endotoxin-induced enhancement of pain perception11Abbreviations:, prostaglandin E receptor subtype 1; IP, prostaglandin I receptor; LPS, lipopolysaccharide; and WT, wild-type mice. (2001) (13)
Induction of histidine decarboxylase by dexamethasone in mastocytoma P-815 cells. (1987) (13)
Cytosol promotes the guanine nucleotide-induced release of the alpha subunit of Gi2 from the membrane of mouse mastocytoma P-815 cells. (1991) (13)
An azido-functionalized isocarbacyclin analogue acting as an efficient photoaffinity probe for a prostacyclin receptor (1992) (13)
Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix. (2008) (13)
Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester (2004) (13)
Potentiation of retinoic acid-induced differentiation of HL-60 cells by prostaglandin EP2 receptor. (1998) (12)
Membrane depolarization by activation of prostaglandin E receptor EP3 subtype of putative serotonergic neurons in the dorsal raphe nucleus of the rat (1996) (12)
Three isoforms of the prostaglandin E receptor EP3 subtype different in agonist-independent constitutive Gi activity and agonist-dependent Gs activity. (1997) (12)
Biological actions of delta 12-prostaglandin J2. (1995) (12)
Differential regulation of thrombin- or ATP-induced mobilization of intracellular Ca2+ by prostacyclin receptor in mouse mastocytoma cells. (1991) (12)
Synergistic effects of cyclic AMP and Ca2+ ionophore A23187 on de novo synthesis of histidine decarboxylase in mastocytoma P-815 cells. (1992) (12)
Calcium dependency of inhibition by arachidonic acid of compound 48/80-induced histamine release from mast cells. (1984) (12)
Prostacyclin (PGI) receptor binding and cyclic AMP synthesis activities of PGI1 analogues, SM-10906 and its methyl ester, SM-10902, in mastocytoma P-815 cells. (1994) (12)
Induction of heme oxygenase by delta 12-prostaglandin J2 in porcine aortic endothelial cells. (1992) (12)
Characterization of functional interaction of carboxylic acid group of agonists and arginine of the seventh transmembrane domains of four prostaglandin E receptor subtypes. (1997) (11)
Calcium uptake in mastocytoma P-815 cells. (1982) (11)
Signal transductions of three isoforms of mouse prostaglandin E receptor EP3 subtype. (1995) (11)
Fibroblast growth factor-stimulated growth of porcine aortic endothelial cells depends on hypoxanthine in fetal bovine serum in culture media. (1989) (11)
Secretion of Poly(3-hydroxybutyrate) Depolymerase by Alcaligenes faecalis T1 (1992) (11)
Aphidicolin: a specific inhibitor of DNA synthesis in synchronous mastocytoma P-815 cells. (1980) (11)
Effect of adenosine 3',5'-monophosphate on growth and several functions of cultured mastocytoma P-815 cells. (1980) (11)
Induction of prostaglandin I2 receptor by tumor necrosis factor α in osteoblastic MC3T3-E1 cells (1999) (11)
Effect of tunicamycin on functions of PGE1 receptors from mouse mastocytoma P-815 cells. (1990) (10)
Inhibition of Dopamine Release by Prostaglandin EP3 Receptor via Pertussis Toxin‐Sensitive and ‐Insensitive Pathways in PC12 Cells (1998) (10)
Effect of hydrocortisone on histidine decarboxylase activity in rat stomach. (1988) (10)
Effect of adenosine and adenosine 5'-monophosphate on cell division of cultured mastocytoma P-815 cells. (1980) (10)
Corrigendum to “Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure–activity relationships of pyrimidine-5-carboxamide derivatives” [Bioorg. Med. Chem. 13 (2005) 4936–4951] (2005) (9)
Enhancement of adenylate cyclase stimulation by prostaglandin E receptor EP3 subtype isoforms with different efficiencies. (1994) (9)
LymphocytesInflux and IL-2 Production in T 2 + Inhibits Store-Operated Sustained Ca (2003) (9)
Prolonged gestation does not extend survival of uterine natural killer lymphocytes in mice deleted in the receptor for prostaglandin F2alpha. (2000) (9)
Glycyrrhetinic acid bound to 11β-hydroxysteriod dehydrogenase in rat liver microsomes (1992) (9)
Effects of glycyrrhizin and glycyrrhetinic acid on dexamethasone-induced changes in histamine synthesis of mouse mastocytoma P-815 cells and in histamine release from rat peritoneal mast cells. (1989) (9)
Gastrin receptor genes are expressed in gastric parietal and enterochromaffin-like cells ofMastomys natalensis (1994) (9)
Co-localization of prostaglandin F synthase, cyclooxygenase-1 and prostaglandin F receptor in mouse Leydig cells (2007) (8)
Fibroblast growth factor-dependent metabolism of hypoxanthine via the salvage pathway for purine synthesis in porcine aortic endothelial cells. (1993) (8)
Apoptosis and related proteins during parturition in prostaglandin F receptor-deficient mice. (2002) (8)
Effect of 7-fluoro prostacyclin, a stable prostacyclin analogue, on cAMP accumulation and prostaglandin binding in mastocytoma P-815 cells. (1983) (8)
Induction of Protein Disulfide Isomerase mRNA by Δ12-Prostaglandin J2 (1996) (8)
Selective coupling of prostaglandin E receptor EP3D to multiple G proteins depending on interaction of the carboxylic acid of agonist and arginine residue of seventh transmembrane domain. (1995) (8)
Expanded Parietal Cell Pool in Transgenic Mice Unable to Synthesize Histamine (2003) (7)
Prostaglandin D2 receptor of mastocytoma P-815 cells--possible regulation by phosphorylation and dephosphorylation. (1989) (7)
Inhibitory effect of tritoqualine (TRQ) on histamine release from mast cells. (1985) (7)
p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice. (2015) (7)
Cloning and expression of a cDNA for rat prostaglandin F2 alpha receptor. (1994) (7)
Induction of protein disulfide isomerase mRNA by delta 12-prostaglandin J2. (1996) (6)
Expanded parietal cell pool in transgenic mice unable to synthesize histamine. (2003) (6)
Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors (2003) (6)
Cytoskeletal regulation of the signal transduction of prostaglandin EP4 receptor. (1998) (6)
Identification of hypoxanthine and inosine in brain dialyzable fraction as stimulators for growth of porcine aortic endothelial cells in response to fibroblast growth factor in either dialyzed serum media or low serum media. (1990) (6)
Membrane orientation of the precursor 74-kDa form of L-histidine decarboxylase (2006) (6)
Properties of protease in mast cell granules. (1980) (5)
Involvement of protein kinase C in thrombin-induced translocation of Gi2 alpha from the membrane to the cytosol in mouse mastocytoma P-815 cells. (1992) (5)
Beta 2-adrenergic regulation of prostaglandin D2 receptor in rabbit platelets. (1987) (5)
Glycyrrhetinic acid bound to 11 beta-hydroxysteroid dehydrogenase in rat liver microsomes. (1992) (5)
Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice (2020) (5)
[Molecular biology of L-histidine decarboxylase]. (1994) (4)
Purification and characterization of S-adenosylhomocysteine hydrolase from mouse mastocytoma P-815 cells. Evidence for cell cycle-specific fluctuation of the enzyme activity. (1985) (4)
Effect of D-glucosamine on growth and several functions of cultured mastocytoma P-815 cells. (1980) (4)
Histamine synthesis in mouse polymorphonuclear neutrophils (2002) (4)
Induction of prostaglandin I(2) receptor by tumor necrosis factor alpha in osteoblastic MC3T3-E1 cells. (1999) (4)
Benzamidine-sensitive proteinase in activated cleavage of recombinant 74 kDa histidine decarboxylase into its 53 kDa form in mastocytoma cells (1998) (4)
Restriction of mast cell proliferation through hyaluronan synthesis by co-cultured fibroblasts. (2012) (4)
Ca-dependent and Ca-independent histamine release from mast cells induced by active components of compound 48/80. (1987) (4)
Characterization of cytosolic pertussis toxin-sensitive GTP-binding protein in mastocytoma P-815 cells. (1991) (4)
Involvement of prostaglandin E2 and its specific receptor subtype EP4 in chronic proliferative cholangitis in the bile ducts of patients with hepatolithiasis (2003) (3)
Fluctuation of fetal rat hepatic histidine decarboxylase activity through the glucocorticoid-ACTH system. (1991) (3)
Studies on the synthesis of compounds related to adenosine 3',5'-cyclic phosphate. IX. Synthesis and cytotoxic effect of adenosine 3',5'-cyclic alkylphosphoramidates. (1991) (3)
Prostaglandin E1 receptor from mouse mastocytoma P-815 cells couples to 60 kDa GTP-binding protein. (1991) (3)
Prostaglandin E2 and F2α in mouse reproduction (2002) (3)
Suppression of CXCR4 expression in mast cells upon IgE-mediated antigen stimulation (2010) (3)
Down-modulation of antigen-induced activation of murine cultured mast cells sensitized with a highly cytokinergic IgE clone. (2016) (3)
Inhibitory mechanism of tritoqualine on histamine release from mast cells. (1986) (3)
Effect of repeated cold stress on mouse stomach histidine decarboxylase. (1995) (3)
Narumiya Membrane depolarization by activation of prostaglandin E receptor EP 3 subtype of putative serotonergic neurons in the dorsal raphe nucleus of the rat (2)
Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice (2015) (2)
Regulation of Mammalian Histamine Synthesis: Histidine Decarboxylase (2010) (2)
Desensitization by glycyrrhetinic acid of other stimulatory substance-induced increases in intracellular calcium in a variety of cell types. (1991) (2)
Upregulation of histidine decarboxylase mRNA expression in scleroderma skin (2001) (2)
Effects of cyclic 3',5'-adenosine monophosphate on inflammations induced by inorganic pyrophosphate, ATP and other phlogistins. (1972) (2)
Effect of adenosine 3',5'-cyclic monophosphate derivatives on acute liver injury induced by carbon tetrachloride. (1992) (2)
Cell cycle specific fluctuations of adenosine 3',5' -monophosphate and prostaglandin binding in synchronized mastocytoma P-815 cells. (1982) (2)
Histamine Biosynthesis and Function (2012) (2)
Inhibitory effect of an intracellular glutathione on delta 12-prostaglandin J2-induced protein syntheses in porcine aortic endothelial cells. (1992) (2)
Inhibition of cellular growth and nutrient transport induced by calcium ionophore A23187 in mastocytoma P-815 cells. (1983) (2)
[Molecular biology of prostaglandin E receptors--expression of multi-function by PGE receptor subtypes and isoforms]. (1998) (2)
De Novo synthesis and posttranslational processing of L-histidine decarboxylase in mice. (1995) (2)
The monocytic differentiation of HL60 induced by rat kidney NADPH-linked high-Km aldehyde reductase protein. (1989) (1)
Effect of the dietary alpha-linolenate/linoleate balance on leukotriene production and histamine release in rats. (1988) (1)
[Molecular biology of prostaglandin receptor and L-histidine decarboxylase]. (1999) (1)
[Molecular structure and function of the prostanoid receptors]. (1995) (1)
Effects of amp and dibutyryl cyclic amp on growth rate and histamine content of mouse mastocytoma p-815 cells. Abstr. (1974) (1)
PGE2-receptor subtype EP4-dependent adherence of mastocytoma P-815 cells to matrix components in subcutaneous tissues overlaying inside surface of air pouch cavity in CDF1 mouse (2008) (1)
12-O-Tetradecanoylphorbol-13-acetate stimulates the transcription of the histidine decarboxylase gene (1993) (1)
Stimulatory effect of guanine nucleotides on prostaglandin E1 binding to murine renal outer medulla. (1991) (1)
Phosphorothioate antisense oligodeoxynucleotides against histidine decarboxylase: a study in mouse mammary epithelial cell cultures (2003) (1)
Induction of 31,000 protein by PGD2-treated vascular endothelial cells. (1991) (1)
Hypoxanthine increases basal and FGF-stimulated growth of porcine aortic endothelial cells in media with calf or newborn bovine serum (1990) (1)
Mice deficient in prostaglandin EP3 receptors do not induce fever but produce psychological stress-induced rise in core temperature (2003) (1)
Interaction of α subunit of GTP‐binding protein Go with a 20‐kDa Triton‐insoluble membrane protein in bovine brain (1992) (1)
Insight into Prostanoid Functions: Lessons from Receptor‐Knockout Mice (2004) (0)
REGULATION OF PROSTAGLANDIN BINDING TO PRECEPTORS IN MASTOCYTOMA P-815 CELLS AND RABBIT PLATELETS (1985) (0)
Calcium compartments of synchronous mastocytoma p-815 cells. Abstr. (1980) (0)
Neutrophils PeritonealProstanoid EP 2 Receptor in Mouse theColony-Stimulating Factor Production via Stimulates Granulocyte 2 Prostaglandin E (2005) (0)
[Effects of cyclic adenosine 3',5'-monophosphate and calcium on cellular function and growth of mast cells]. (1984) (0)
Hepatitis-treating agent (1992) (0)
[Eicosanoids and their receptors]. (1990) (0)
Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice (2020) (0)
Transcription Factor Nur77 (2000) (0)
Inhibition of salvage synthesis of nucleic acid by adenosine 3',5'-cyclic decylphosphoramidate in mastocytoma P-815 cells. (1992) (0)
EFFECT OF ARACHIDONIC ACID ON PERTUSSIS TOXIN-CATALYZED ADP-RIBOSYLATION OF Gi2 IN RBL-2H3 CELLS (1991) (0)
Prostaglandin binding and cyclic amp (camp) production in mastocytoma p-815 cells. Abstr. (1979) (0)
Interleukin-4-mediated suppression of histamine synthesis in a murine mast cell line, BNu-2cl3. (2009) (0)
New carboxamide heterociclic derivatives. (2000) (0)
Induction of Prostaglandin I2 Receptor in Murine Osteoblastic Cell (2001) (0)
2N1415 Distribution and stability of prostaglandin receptors on a CHO cell estimated by AFM (2002) (0)
An aromatic amino acid in the i2 loop is essential for association of Gs protein in the prostaglandin E receptors EP2 and EP3 (2005) (0)
Impaired activation of mast cells upon IgE-mediated antigen stimulation in a stroke-prone spontaneously hypertensive rat strain, SHRSP.Z. (2010) (0)
Intracellular localization of histidine decarboxylase (2001) (0)
Prostaglandin E receptors, their preparation and DNA (1993) (0)
L-Histidine Decarboxylase from Mouse Mastocytoma P-815 Cells: The Amino Acid Sequence as Derived from cDNA Sequence (1991) (0)
Prostaglandin receptors IP and EP mediating regulation of tumor necrosis factor-alpha and interleukin-10 production (2002) (0)
Reproductive function of prostanoids: Lessons from receptor-deficient mice (2002) (0)
Effect of pyruvate on thyroid hormone-induced lipolysis in rat adipose tissue in vitro. (1977) (0)
[Molecular structures of eicosanoid receptors]. (1996) (0)
Up-regulation of prostaglandin D2 receptors by agonist binding to beta-adrenoceptors in rabbit platelets. (1985) (0)
Roles of receptor gene induction in prostanoid physiology (2003) (0)
Molecular Biology of Prostaglandin Receptor and L-Histidine Decarboxylase (2010) (0)
Prostanoids/PAF and Inflammation: Their Roles Revealed by Molecular Biology and Knock-out Mouse Studies (2014) (0)
Structures and functions of prostanoid receptors (1995) (0)
[Structure and function of prostaglandin receptors]. (1999) (0)
ヒスタミン欠損は胃粘膜形態を変化する:ヒスチジンデカルボキシラーゼ-欠陥マウスと肥満細胞-欠陥マウスの比較 (2004) (0)
An Azido‐Functionalized Isocarbacyclin Analogue Acting as an Efficient Photoaffinity Probe for a Prostacyclin Receptor. (1992) (0)
Expressions of cyclooxygenase-2 (COX-2) and prostaglandin E receptors (EPs) in gallbladder carcinoma (GBca)-association with tumor progression (2001) (0)
Effect of environmental substances on mast cell function in inflammation. (1986) (0)
Role of prostaglandin e receptors in LPS-induced ACTH release (1999) (0)
Molecular pharmacology of prostaglandin E receptor subtypes –structure, signal transduction, and knockout mouse studies– (2000) (0)
Induction of dexamethasone (DM) of histidine decarboxylase (HDC) in mast cells (1986) (0)
Cloning of a prostanoid receptor cDNA from mouse lung. 1. (1992) (0)

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