Alfred J. Crowle
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Alfred J. Crowlebiology Degrees
Biology
#12700
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#16195
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Microbiology
#756
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#832
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Immunology
#855
World Rank
#878
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Biology
Alfred J. Crowle's Degrees
- PhD Immunology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Alfred J. Crowle Influential?
(Suggest an Edit or Addition)Alfred J. Crowle's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria (1985) (326)
- Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic (1991) (317)
- A simplified micro double-diffusion agar precipitin technique. (1958) (255)
- Inhibition by 1,25(OH)2-vitamin D3 of the multiplication of virulent tubercle bacilli in cultured human macrophages (1987) (252)
- Delayed hypersensitivity in the mouse. (1975) (180)
- Chlorpromazine: a drug potentially useful for treating mycobacterial infections. (1992) (133)
- Murine thyroiditis: importance of adjuvant and mouse strain for the induction of thyroid lesions. (1971) (126)
- Comparison of 15 laboratory and patient-derived strains of Mycobacterium avium for ability to infect and multiply in cultured human macrophages (1986) (125)
- Relative permissiveness of macrophages from black and white people for virulent tubercle bacilli (1990) (85)
- Inhibition by retinoic acid of multiplication of virulent tubercle bacilli in cultured human macrophages (1989) (82)
- An improved stain for immunodiffusion tests. (1977) (74)
- Preliminary demonstration of human tuberculoimmunity in vitro (1981) (70)
- Effectiveness of ofloxacin against Mycobacterium tuberculosis and Mycobacterium avium, and rifampin against M. tuberculosis in cultured human macrophages. (1988) (55)
- Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system. (1990) (54)
- Antibodies against the Ag2 fimbriae of Actinomyces viscosus T14V inhibit lactose-sensitive bacterial adherence (1982) (54)
- Inhibition of tubercle bacilli in cultured human macrophages by chloroquine used alone and in combination with streptomycin, isoniazid, pyrazinamide, and two metabolites of vitamin D3 (1990) (53)
- Inhibition by pyrazinamide of tubercle bacilli within cultured human macrophages. (1986) (49)
- Inhibition by streptomycin of tubercle bacilli within cultured human macrophages. (1984) (49)
- Delayed hypersensitivity in health and disease (1962) (46)
- Preferential development by mice of delayed hypersensitivity to purified basic proteins. (1968) (46)
- Natural mycobacteriostatic activity in human monocyte-derived adherent cells. (2015) (42)
- Transferrin, iron, and serum lipids enhance or inhibit Mycobacterium avium replication in human macrophages. (1993) (41)
- Defects in sera from acquired immunodeficiency syndrome (AIDS) patients and from non-AIDS patients with Mycobacterium avium infection which decrease macrophage resistance to M. avium (1989) (36)
- Contact sensitivity in mice. (1961) (33)
- Preparatory electroimmunodiffusion for making precipitins to selected native antigens. (1972) (32)
- Immunizing constituents of the tubercle bacillus. (1958) (32)
- 1,25(OH)2-vitamin D3 synergizes with pyrazinamide to kill tubercle bacilli in cultured human macrophages. (1989) (31)
- Split tolerance affecting delayed hypersensitivity and induced in mice by pre-immunization with protein antigens in solution. (1966) (31)
- Adoptive transfer of immunologic tolerance into normal mice. (1969) (31)
- Delayed hypersensitivity in mice. (1959) (30)
- The Tubercle Bacillus Human Macrophage Relationship Studied In Vitro (1988) (30)
- Delayed Hypersensitivity in Mice: Its Detection by Skin Tests and Its Passive Transfer (1959) (30)
- Lymphokine-induced mycobacteriostatic activity in mouse pleural macrophages (1982) (30)
- A COMPARISON OF THYMECTOMIZED AND ANTITHYMOCYTE SERUM-TREATED MICE IN THEIR DEVELOPMENT OF HYPERSENSITIVITY TO PROTEIN ANTIGENS. (1965) (30)
- Immunization against tuberculosis: what kind of vaccine? (1988) (30)
- Protein Abnormalities in Adult Respiratory Distress Syndrome, Tuberculosis, and Cystic Fibrosis Sera 1 (1987) (30)
- Interpretation of immunodiffusion tests. (1960) (29)
- Investigation of the mechanisms by whick "enhancing" antiserum prevents induction of delayed hypersensitivity to protein antigens in mice. (1969) (27)
- Delayed hypersensitivity in several strains of mice studied with six different tests. (1959) (27)
- Intracellular killing of mycobacteria. (1990) (26)
- Four modifications of the micro agar diffusion precipitin test. (1960) (25)
- Comparison of the abilities of Mycobacterium avium and Mycobacterium intracellulare to infect and multiply in cultured human macrophages from normal and human immunodeficiency virus-infected subjects (1992) (25)
- INHIBITION OF THE DEVELOPMENT OF DELAYED HYPERSENSITIVITY BY TREATMENT WITH ANTISERUM. (1965) (24)
- Inhibition by normal human serum of Mycobacterium avium multiplication in cultured human macrophages (1989) (23)
- The effect of ethambutol on tubercle bacilli within cultured human macrophages. (1985) (22)
- Crossed immunoelectrophoresis: Qualitative and quantitative considerations (1982) (22)
- Combined effect of pyrazinamide and ofloxacin within the human macrophage. (1996) (21)
- Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages. (1988) (20)
- Comparative Abilities of Various Metabolites of Vitamin D to Protect Cultured Human Macrophages Against Tubercle Bacilli (1990) (20)
- Induction of delayed hypersensitivity to protein antigens in mice without Freund adjuvants. (1977) (17)
- Mouse pleural macrophages: characterization and comparison with mouse alveolar and peritoneal macrophages. (1982) (17)
- A simplified agar electrophoretic method for use in antigen separation and serologic analysis. (1956) (17)
- The combined effect of rifampin and pyrazinamide within the human macrophage. (1992) (17)
- Enhancement of growth of Mycobacterium lepraemurium in macrophages by gamma interferon (1989) (17)
- DURATION OF SOME CUTANEOUS HYPERSENSITIVITIES IN MICE. (1964) (16)
- Factors which affect induction of delayed hypersensitivity to protein antigens in mice (1962) (15)
- Delayed hypersensitivity in mice to dextran. (1967) (15)
- Tubercle bacillary extracts immunogenic for mice. 1. Factors affecting demonstration of their activity. (1961) (15)
- Pyrazinamide is not active in vitro against Mycobacterium avium complex. (1986) (15)
- Replication of lyophilized and cultured BCG in human macrophages. (1983) (15)
- Crossed immunoelectrophoresis: Technique (1981) (14)
- IMMUNOLOGIC UNRESPONSIVENESS TO PROTEIN ANTIGENS INDUCED IN ADULT HYPERSENSITIVE MICE. (1963) (14)
- Tubercle bacillary extracts immunogenic for mice. 2. Water-soluble proteinaceous extracts. (1961) (13)
- Crossed Immunoelectrophoretic Analysis of ARDS Lavage Proteins (1987) (13)
- Specificity of Inhibition by Antiserum of the Development of Immediate and Delayed Hypersensitivities in Mice∗ (1968) (13)
- Templates for antiserum application in immunoelectrophoresis and two-dimensional electroimmunodiffusion. (1977) (13)
- Regression and differentiation of neuroblastoma tumors in mice treated with differentiating agents--prostaglandin E1 and a phosphodiesterase inhibitor, RO 20-1724. (1982) (12)
- Tubercle bacillary extracts immunogenic for mice. 3. Chemical degradation studies on the immunogen extracted from tubercle bacilli by trypsin digestion. (1962) (12)
- Specific Immunologic Unresponsiveness to Delayed Hypersensitivity Elicited in Adult Mice.∗ (1962) (12)
- Characterization of contrasensitizing antibodies. (1974) (11)
- Characterization of inhibition of Mycobacterium avium replication in macrophages by normal human serum (1992) (11)
- Tuberculin skin reactions in mice hypersensitized by vaccination with living avirulent tubercle bacilli. (1960) (11)
- Passively transferred delayed hypersensitivity reactions in mice and guinea-pigs. (1965) (11)
- TUBERCLE BACILLARY EXTRACTS IMMUNOGENIC FOR MICE. 6. COMPARATIVE IMMUNOGENICITY OF TRYPSIN EXTRACT OF TUBERCLE BACILLI IN MICE AND GUINEA PIGS. (1964) (11)
- Tubercle Bacillary Extracts Immunogenic for Mice. 4. Lipids.∗ (1962) (11)
- Anaphylaxis in the mouse--a model for using two-dimensional electroimmunodiffusion to study pathological changes in multiple serum proteins simultaneously. (1979) (11)
- Studies on the Secretion of Serum Proteins from Rat Hepatoma Cells (1984) (11)
- Adaptive transfer of neonatally induced tolerance into normal mice. (1973) (10)
- Enhancement by cadmium of double-diffusion precipitin reactions. (1958) (10)
- Studies on the induction and time course of repressionof delayed hypersensitivity in the mouse by low and high doses of antigen. (1970) (10)
- Identification of alpha1-lipoproteins in crossed immunoelectrophoresis. (1979) (9)
- Resistance of neonatal tolerance in mice to abrogation by normal immunocytes. (1973) (9)
- Antigenic specificities of antibodies suppressing induction of delayed hypersensitivity in mice to dinitrophenylated proteins. (1973) (9)
- Enhancement by various cations of the double-diffusion precipitin test. (1960) (9)
- Attempts to induce early-type ("Jones-Mote") delayed hypersensitivity in mice. (1965) (9)
- A Comparison of n-Hexadeeane and Mineral Oil Emulsions in Induction of Hypersensitivity in Mice.∗ (1966) (9)
- Crossed immunoelectrophoresis of mouse serum. (1981) (8)
- Crossed immunoelectrophoresis of rat serum. (1984) (8)
- Reversed electroimmunodiffusion for quantitating precipitins. (1974) (8)
- Differential serum protein binding of benzidine- and benzidine-congener based dyes and their derivatives (1985) (8)
- THE EFFECTIVENESS OF A THIOCARBANILIDE (ISOXYL) AS A THERAPEUTIC DRUG IN MOUSE TUBERCULOSIS. (1963) (8)
- Culture conditions required for primary isolation and study of mouse blood monocytes. (1982) (8)
- Adoptive Transfer of Low Zone Tolerance into Normal Adult Mice 1 (1972) (7)
- Evans blue dye adjuvant enhances delayed hypersensitivity while blocking immunity to Mycobacterium tuberculosis in mice (1981) (7)
- Mechanisms involved in the antibody-mediated suppression of tuberculin-type delayed hypersensitivity. II. The sensitivity of tolerance induction to cyclophosphamide pretreatment and splenectomy, and the demonstration of active suppression. (1981) (7)
- Chapter 4 – Double Diffusion Tests (1973) (7)
- Studies of antituberculosis chemotherapy with an in vitro model of human tuberculosis. (1986) (6)
- Adjuvanticity of Evans blue dye: preliminary characterization of its mechanisms and mode of application in mice. (1978) (6)
- A hanging drop macrophage function test. (1978) (6)
- Chapter 6 – Electroimmunodiffusion (1973) (6)
- Factors affecting production of contrasensitizing antisera in mice. (1976) (6)
- Crossed-immunoelectrophoretic analysis of serum abnormalities following thermal injury (1984) (5)
- Immunodiffusion analyses useful in clinical chemistry. (1978) (5)
- Tubercle bacillary extracts immunogenic for mice. 5. Specificity of tuberculo-immunity induced by trypsin extracts of tubercle bacilli. (1963) (5)
- Non-mycobacterial Adjuvant which mediates Experimental Aspermatogenesis (1966) (5)
- Identification of transcalciferin as a major component of human parotid saliva by crossed immunoelectrophoretic mapping. (1982) (4)
- Corynebacterium rubrum nov. spec. A gram-positive nonacid-fast bacterium of unusually high lipid content (2006) (4)
- COMPARISON of the chemotherapeutic activities of INH, gatalone and glucuronolactone in tuberculous mice by the lung density technique. (1958) (4)
- Lung density as a measure of tuberculous involvement in mice. (1958) (4)
- SECONDARY PRECIPITATION IN IMMUNODIFFUSION TESTS. (1963) (3)
- Identification and characterization of guinea-pig antibodies that contrasensitize in mice. (1978) (3)
- Effects of aging in A/J mice on delayed and arthus hypersensitivities, anamnesis and a low-dose tolerance. (1981) (3)
- An attempt to produce emphysema in the guinea pig. (1959) (3)
- Adoptive transfer of neonatal tolerance into normal mice. Abstr. (1971) (3)
- Mechanisms involved in the antibody-mediated suppression of tuberculin-type delayed hypersensitivity: the effects of antigen concentration on tolerance induction, the ability of antigen-antibody complexes to render tolerant and the effects of toleration on antigen-induced in vitro proliferation. (1981) (3)
- Importance of Phosphate in Freund Adjuvant 1 (1972) (2)
- Crossed Immunoelectrophoresis of Sera from Adult through Aged Mice (1982) (2)
- Suppression of tuberculoimmunity in mice by Evans blue dye (1982) (2)
- [Cellular and molecular nature of tubercular immunity in man]. (1983) (2)
- Microimmunoelectrophoresis: comparison of template with nontemplate methods. (1962) (2)
- DELAYED HYPERSENSITIVITY AND ITS ALLERGIC IMPLICATIONS. (1964) (2)
- The role of immunologic tolerance in immunologic response. (1966) (2)
- TUBERCLE BACILLARY EXTRACTS IMMUNOGENIC FOR MICE. 7. ELECTROPHORETIC ANALYSES. (1965) (2)
- Crossed Immunoelectrophoresis of Neonatal and Juvenile Mouse Serum (1982) (2)
- Gelatin for Immunodiffusion of Basic Protein.∗ (1967) (2)
- Chapter 3 – Single Diffusion Tests (1973) (1)
- Chapter 5 – Immunoelectrophoresis (1973) (1)
- Crossed immunoelectrophoresis: Normal variation among serum proteins (1981) (1)
- Antigen-Antibody Precipitation Contrasted in Gels of High and Physiological Salt Concentrations (1961) (1)
- TUBERCULOIMMUNITY INDUCED BY KILLED TUBERCLE BACILLI AND THEIR CONSTITUENTS. (1964) (1)
- Delayed hypersensitivity. (1960) (1)
- Resistance of SJL mice to immunosuppression by antibodies. (1978) (1)
- Chapter 7 – Ancillary Immunodiffusion Techniques (1973) (0)
- VITAMIN D AND HUMAN ANTITUBERCULOSIS IMMUNITY. (1988) (0)
- [Determination of the sensitivity of tuberculosis bacteria to pyrazinamide using human macrophage culture]. (1990) (0)
- A simplified modification of the triangular double-diffusion agar precipitin test. (1958) (0)
- Quantitative immunoelectrophoresis: Scandinavian Journal of Immunology, Supplement No. 2, 1975. N.H. Axelson, Ed., Universitetsforlaget, Oslo, Norway, 1975 (230 pp., illus.) $ 26.00 (1976) (0)
- IMMUNODIFFUSION: SOME CONSIDERATIONS IN ITS USE. (1963) (0)
- Anaphylactic and precipitating antibody responses of aging A/J female mice. (1982) (0)
- Inhibition of mycobacterial replication in cultured human macrophages by 1 25 dihydroxyvitamin d 3 (1987) (0)
- Chapter 1 – Basic Information (1973) (0)
- Tubercle bacillary extracts immunogenic for mice. 8. Storage stability of trypsin-extracted immunogen. (1968) (0)
- Interferon-gamma and mycobacterial infections. (1988) (0)
- Suppressed multiplication of pulmonary tubercle bacilli in bacillary trypsin extract-immunized mice (1969) (0)
- Anaphylaxis inthe Mouse-a Modelfor UsingTwo-Dimensional Electroimmunodiffusion to StudyPathological Changesin Multiple SerumProteinsSimultaneously (1979) (0)
- Chapter 2 – General Information (1973) (0)
- Filtration of mycobacteria from organic solvents. (1958) (0)
- Delayed Hypersensitivity. (1962) (0)
- Identificationof a1-Lipoproteinsin CrossedImmunoelectrophoresis (2004) (0)
- Contents, Vol. 28, 1965 (1965) (0)
- Lack of any antagonism between pyridoxine and isoniazid in the chemotherapy of acutely or chronically tuberculous mice (1960) (0)
- Crossed immunoelectrophoresis: Application (1981) (0)
- Some factors affecting production by mice of 'enhancing' antibody. Abstr. (1969) (0)
- IMMUNIZING CONSTITUENTS OF THE TUBERCLE BACILLUS (1958) (0)
- Chapter 8 – History (1973) (0)
- Abrogation of 'preimmunization' tolerance by adoptive transfer. Abstr. (1967) (0)
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