Alastair J. J. Wood
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(Suggest an Edit or Addition)Alastair J. J. Wood's Published Works
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Published Works
- The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. (1998) (1106)
- Molecular basis of ethnic differences in drug disposition and response. (2001) (596)
- Reduced β‐adrenoceptor sensitivity in the elderly (1979) (563)
- Increased drug delivery to the brain by P‐glycoprotein inhibition (2000) (424)
- Interrelationship Between Substrates and Inhibitors of Human CYP3A and P-Glycoprotein (1999) (422)
- Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. (2000) (421)
- Reduction of liver blood flow and propranolol metabolism by cimetidine. (1981) (396)
- The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. (2001) (379)
- Genetic variability in CYP3A5 and its possible consequences. (2004) (313)
- Exacerbation of Vasotonic Angina Pectoris by Propranolol (1982) (297)
- CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5′‐promoter region polymorphism (2000) (278)
- P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies. (1999) (267)
- Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans. (2001) (267)
- Alterations in leukocyte β-receptor affinity with aging: a potential explanation for altered β-adrenergic sensitivity in the elderly (1984) (230)
- Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites. (1989) (229)
- Interaction of Morphine, Fentanyl, Sufentanil, Alfentanil, and Loperamide with the Efflux Drug Transporter P-glycoprotein (2002) (226)
- Regulation of human leukocyte beta receptors by endogenous catecholamines: relationship of leukocyte beta receptor density to the cardiac sensitivity to isoproterenol. (1981) (210)
- Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world. (1999) (191)
- Pharmacogenetic determination of the effects of codeine and prediction of drug interactions. (1996) (180)
- Increased toxicity and reduced clearance of lidocaine by cimetidine. (1982) (173)
- A common β1‐adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to β‐blockade (2003) (154)
- Vasodilation in black Americans: Attenuated nitric oxide‐mediated responses (1997) (151)
- Direct measurement of propranolol bioavailability during accumulation to steady-state. (1978) (145)
- Increased Vascular Adrenergic Vasoconstriction and Decreased Vasodilation in Blacks: Additive Mechanisms Leading to Enhanced Vascular Reactivity (2000) (143)
- Stereoselective disposition of carvedilol is determined by CYP2D6 (1995) (132)
- Changes in plasma drug binding and α1‐acid glycoprotein in mother and newborn infant (1981) (131)
- Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men (1993) (130)
- The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone. (1990) (130)
- Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals. (1999) (125)
- Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat. (1979) (125)
- Attenuation of isoproterenol-mediated vasodilatation in blacks. (1995) (125)
- Reduced beta-adrenoceptor sensitivity in the elderly. (1979) (116)
- Dynamic regulation of leukocyte beta adrenergic receptor-agonist interactions by physiological changes in circulating catecholamines. (1983) (115)
- Stereoselective disposition and pharmacologic activity of propafenone enantiomers. (1989) (112)
- Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation. (1997) (112)
- Altered drug binding due to the use of indwelling heparinized cannulas (heparin lock) for sampling (1979) (111)
- Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. (2001) (105)
- Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature. (1998) (103)
- Influence of genetic polymorphism on the metabolism and disposition of encainide in man. (1984) (102)
- Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance. (1992) (101)
- Inhibition of stimulated interleukin-2 production in whole blood: a practical measure of cyclosporine effect. (1999) (99)
- Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin. (1990) (98)
- Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects. (1999) (96)
- Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension. (1995) (95)
- The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome. (2011) (92)
- The Influence of Cirrhosis on Steady-State Blood Concentrations of Unbound Propranolol after Oral Administration (1978) (92)
- Polymorphic ability to metabolize propranolol alters 4‐hydroxypropranolol levels but not beta blockade (1984) (86)
- Editorial: Propranolol Withdrawal Syndrome Why? (1978) (86)
- The erythromycin breath test reflects P‐glycoprotein function independently of cytochrome P450 3A activity (2006) (85)
- Differential in Vivo Sensitivity to Inhibition of P-glycoprotein Located in Lymphocytes, Testes, and the Blood-Brain Barrier (2006) (84)
- Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops. Potential for oral-ophthalmic drug interaction. (1995) (84)
- Effect of sympathoinhibition on exercise performance in patients with heart failure. (1997) (83)
- Human β2‐adrenergic receptor polymorphisms: No association with essential hypertension in black or white Americans (2000) (81)
- Determinants of anticoagulant control in patients receiving warfarin. (1977) (80)
- The effect of sildenafil on nitric oxide–mediated vasodilation in healthy men (2001) (79)
- A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade. (2003) (78)
- Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro. (2000) (72)
- Influence of Age and Smoking on Drug Kinetics in Man Studies Using Model Compounds (1980) (71)
- Low sodium intake corrects abnormality in β‐receptor–mediated arterial vasodilation in patients with hypertension: Correlation with β‐receptor function in vitro (1990) (68)
- A Multi-Investigator/Institutional DNA Bank for AIDS-Related Human Genetic Studies: AACTG Protocol A5128 (2003) (68)
- Quinidine reduces clearance of (+)‐propranolol more than (−)‐propranolol through marked reduction in 4‐hydroxylation (1990) (67)
- Effects of cimetidine on the elimination and actions of ethanol. (1982) (67)
- Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent. (1999) (66)
- Phenytoin metabolic ratio: a putative marker of CYP2C9 activity in vivo. (2001) (66)
- β2-Adrenergic receptor genotype and preterm delivery ☆ ☆☆ (2002) (66)
- Leukocyte beta-receptor alterations in hypertensive subjects. (1984) (64)
- Interethnic difference in omeprazole's inhibition of diazepam metabolism (1995) (63)
- Halothane‐induced Hepatic Necrosis in Triiodothyronine‐pretreated Rats (1980) (59)
- No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia. (2004) (58)
- Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension. (1999) (57)
- Induction of propranolol metabolism by rifampicin. (1983) (57)
- Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects. (1997) (56)
- Metabolism of cytochrome P4503A substrates in vivo administered by the same route: Lack of correlation between alfentanil clearance and erythromycin breath test (1994) (56)
- Ethnic differences in response to morphine. (1995) (55)
- Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade (2008) (55)
- Propranolol disposition in renal failure. (1980) (54)
- Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity. (1996) (53)
- Pharmacologic differences between beta blockers. (1984) (53)
- Ethnic and genetic determinants of omeprazole disposition and effect (1996) (52)
- In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism. (2001) (52)
- Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly. (1984) (51)
- Effect of heparin administration on plasma binding of benzodiazepines. (1980) (50)
- Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard. (1997) (49)
- The Effect of Halothane on Drug Disposition: Contribution of Changes in Intrinsic Drug Metabolizing Capacity and Hepatic Blood Flow (1985) (49)
- Pharmacokinetic Drug Interactions with Propranolol (1983) (46)
- Electrophysiologic actions of high plasma concentrations of propranolol in human subjects. (1983) (46)
- Propranolol Binding in Plasma during Cardiopulmonary Bypass (1979) (45)
- The Effects of Tadalafil on Cold‐induced Vasoconstriction in Patients with Raynaud's Phenomenon (2007) (45)
- Ethnic differences in drug disposition and response. (1998) (45)
- Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity. (1996) (44)
- Cyclosporine impairs vasodilation without increased sympathetic activity in humans. (1995) (44)
- EFFECT OF N-ACETYLCYSTEINE ON HEPATIC COVALENT BINDING OF PARACETAMOL (ACETAMINOPHEN) (1977) (43)
- Changes in plasma drug binding and alpha 1-acid glycoprotein in mother and newborn infant. (1981) (42)
- CYP2A6 genetic variation and dexmedetomidine disposition (2012) (42)
- Abnormalities of the QT interval in primary disorders of autonomic failure. (1998) (42)
- Dose–related effect of triazolam on postural sway (1991) (40)
- Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses (2003) (39)
- Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo. (2004) (39)
- Optimization of high-performance liquid chromatographic assay for catecholamines. Determination of optimal mobile phase composition and elimination of species-dependent differences in extraction recovery of 3,4-dihydroxybenzylamine. (1992) (39)
- Effects of anesthesia on norepinephrine kinetics. Comparison of propofol and halothane anesthesia in dogs. (1991) (39)
- Ethnic and Genetic Determinants of Cardiovascular Response to the Selective &agr;2-Adrenoceptor Agonist Dexmedetomidine (2008) (38)
- Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine (1996) (38)
- Impaired drug metabolism in experimental cirrhosis in the rat. (1978) (38)
- Drugs and Anesthesia: Pharmacology for Anesthesiologists (1989) (36)
- Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein (2008) (36)
- Beta2 adrenoceptor THR164ILE polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo (2003) (36)
- Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks. (1997) (35)
- Perioperative beta blockade with propranolol: reduction in myocardial oxygen demands and incidence of atrial and ventricular arrhythmias. (1984) (35)
- β‐Adrenergic receptor—mediated release of norepinephrine in the human forearm (1993) (35)
- Variation in the &agr;2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo (2005) (35)
- Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race. (2001) (34)
- Effect of i.v. anaesthesia with propofol on drug distribution and metabolism in the dog. (1991) (33)
- Variations in the α2A‐adrenergic receptor gene and their functional effects (2006) (32)
- Elimination kinetics of labetalol in severe renal failure. (1982) (32)
- Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade. (1990) (32)
- Simultaneous determination of codeine and its seven metabolites in plasma and urine by high-performance liquid chromatography with ultraviolet and electrochemical detection. (1998) (32)
- Racial Differences in Drug Response (1989) (31)
- beta2-Adrenergic receptor genotype and preterm delivery. (2002) (31)
- Long‐term exposure to β2‐receptor agonist specifically desensitizes β‐receptor—mediated venodilation (1993) (31)
- The sympathetic response to profound hypothermia and circulatory arrest in infants (1980) (30)
- Disposition kinetics of encainide and metabolites. (1986) (30)
- A clinical study of sensitivity to sodium nitroprusside during controlled hypotensive anesthesia in young and elderly patients. (1986) (30)
- Triazolam in cirrhosis: Pharmacokinetics and pharmacodynamics (1993) (30)
- Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers. (2003) (30)
- G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy. (2003) (29)
- Interaction of topical and oral timolol in glaucoma. (1979) (28)
- β‐Receptor antagonism does not fully explain esmolol‐induced hypotension (1994) (28)
- Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro. (1990) (27)
- Medicines Evaluation and Monitoring Group: Central Nervous System Effects of Pentazocine (1974) (27)
- Dietary sodium intake modulates vasodilation mediated by nitroprusside but not by methacholine in the human forearm. (1995) (26)
- A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism. (1990) (25)
- Simultaneous determination of propranolol enantiomers in plasma by high-performance liquid chromatography with fluorescence detection. (1989) (25)
- Alpha2-Adrenergic Receptor–Induced Vascular Constriction in Blacks and Whites (2004) (24)
- Genetic Variations in the &agr;2A-Adrenoreceptor Are Associated With Blood Pressure Response to the Agonist Dexmedetomidine (2011) (24)
- A modified, sensitive liquid chromatographic method for measurement of propranolol with fluorescence detection. (1986) (24)
- Encainide disposition in patients with renal failure (1986) (24)
- Sympathoinhibitory response to clonidine is blunted in patients with heart failure. (1997) (24)
- Desensitization of vascular response in vivo: contribution of genetic variation in the α2B-adrenergic receptor subtype (2010) (24)
- Variations in the alpha2A-adrenergic receptor gene and their functional effects. (2006) (24)
- Drug interaction studies and encainide use in renal and hepatic impairment. (1986) (24)
- Physiological regulation of beta-receptors in man. (1982) (23)
- A new method for constant plasma drug concentrations: application to lidocaine. (1984) (23)
- Genetic variants in the &agr;2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses (2008) (23)
- Lack of correlation between arterial and venous beta-adrenergic receptor sensitivity. (1997) (22)
- Variability in beta-adrenergic receptor response in the vasculature: Role of receptor polymorphism. (2002) (22)
- GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans. (2009) (21)
- Differences in stereoselective disposition of propranolol do not explain sensitivity differences between white and Chinese subjects: Correlation between the clearance of (−)‐ and (+)‐propranolol (1990) (21)
- Quantitation of loperamide and N-demethyl-loperamide in human plasma using electrospray ionization with selected reaction ion monitoring liquid chromatography-mass spectrometry. (2000) (20)
- Routine Therapeutic Monitoring of Lamotrigine in Epileptic Patients Using a Simple and Rapid High Performance Liquid Chromatographic Technique (1995) (20)
- Lack of effect of ageing on the stereochemical disposition of propranolol. (1992) (20)
- Plasma binding of pancuronium: effects of age, sex, and disease. (1983) (20)
- Comparison of the effects of isoflurane or fentanyl-nitrous oxide anaesthesia on propranolol disposition in dogs. (1988) (19)
- Disproportionate Decrease in &agr;- Compared With &bgr;-Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation (2002) (19)
- Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test. (1995) (18)
- Contrasting Effects on Halothane Hepatotoxicity in the Phenobarbital-Hypoxia and Triiodothyronine Model: Mechanistic Implications (1983) (18)
- Determination of low plasma timolol concentrations following topical application of timolol eye drops in humans by high-performance liquid chromatography with electrochemical detection. (1994) (17)
- Sensitive assay for triazolam in plasma following low oral doses. (1992) (17)
- Biological determinants of propranolol disposition in normal subjects and patients with cirrhosis [proceedings]. (1977) (17)
- Effect of the α2C-adrenoreceptor deletion322–325 variant on sympathetic activity and cardiovascular measures in healthy subjects (2007) (17)
- Elevated Plasma Free Drug Concentrations of Propranolol and Diazepam During Cardiac Catheterization (1980) (16)
- The Effect of Cimetidine on Anesthetic Metabolism and Toxicity (1986) (16)
- Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise (2012) (16)
- Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol. (1995) (16)
- Effects of feeding on the systemic clearance of indocyanine green and propranolol blood concentrations and plasma binding. (1983) (16)
- Racial differences in drug response. (1989) (15)
- Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection. (1987) (15)
- α2B Adrenergic receptor 301-303 deletion polymorphism and vascular α2 adrenergic receptor response (2005) (15)
- ACUTE EFFECT OF HALOTHANE (H) ON DRUG DISTRIBUTION (1989) (15)
- α‐Adrenergic blockade makes minimal contribution to ketanserin's hypotensive effect (1988) (15)
- Cerebrospinal fluid concentration of metoprolol in a hypertensive patient. (1977) (14)
- Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor. (1984) (14)
- The effect of halothane on morphine disposition: relative contributions of the liver and kidney to morphine glucuronidation in the dog. (1990) (14)
- Alpha 1A-adrenergic receptor polymorphism and vascular response. (2004) (14)
- Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo (2011) (13)
- Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep. (1998) (13)
- Norepinephrine release in the human forearm: effects of epinephrine. (1997) (13)
- Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio. (1999) (12)
- Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response. (2005) (12)
- Increased suppression of exercise‐induced increase in renin by propranolol in Chinese subjects (1991) (12)
- Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol. (1995) (11)
- Enprostil, in contrast to cimetidine, does not inhibit propranolol metabolism (1986) (11)
- Halothane inhibition of propranolol metabolism is stereoselective. (1989) (10)
- Variability of fentanyl pharmacokinetics in man. Computer predicted plasma concentrations for three intravenous dosage regimens. (1985) (10)
- Variation in the &agr;2A adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose (2013) (10)
- Effect of inhibitors of prostaglandin synthesis on hepatic drug clearance. (1983) (9)
- Cimetidine alters plasma catecholamine levels and cortisol and aldosterone excretion. (1982) (9)
- Contribution of differences in plasma binding of propranolol to ethnic differences in sensitivity. Comparison between Chinese and Caucasians. (1993) (9)
- Management of hypertension in the elderly. (1981) (9)
- Plasma Binding of Pancuronium: Effects of Age, Sex, and Disease (1980) (8)
- Exacerbation of ischemia in vasotonic angina pectoris by propranolol (1981) (7)
- Alfentanil Disposition In Vivo Is Mediated By Cyp3a4 In Humans (1994) (7)
- Interindividual differences in beta-receptor density contribute to variability in response to beta-adrenoceptor antagonists. (1989) (6)
- Alpha- and beta-adrenergic agonists and antagonists (1983) (6)
- Exacerbation ofVasotonic Angina Pectoris byPropranolol (1982) (6)
- Effect on apparent liver blood flow of histamine‐receptor blockers and inhibition of prostaglandin synthesis (1983) (6)
- Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women (2005) (6)
- Basal and stimulated sympathetic responses after epinephrine: no evidence of augmented responses. (1998) (5)
- Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man (1984) (5)
- Evidence of increased CPY3A4 activity in African Americans (1996) (5)
- The effect of sildenafil on QT interval in healthy men (2001) (5)
- Long-term exposure to beta 2-receptor agonist specifically desensitizes beta-receptor-mediated venodilation. (1993) (5)
- Erythromycin breath test (multiple letters) (2000) (4)
- PROLONGED NEUROMUSCULAR BLOCKADE (1973) (4)
- CIMETIDINE PROTECTS AGAINST HALOTHANE-INDUCED HEPATOTOXICITY (1982) (4)
- Altered β-Adrenoceptor Internalization Does Not Explain Reduced β-Adrenergic Responsiveness in the Elderly (1989) (4)
- Ethnic and genetic determinants of omeprazole disposition and effect (1996) (4)
- Mibefradil is a potent inhibitor of both CYP3A and P‐glycoprotein (P‐GP) (1999) (4)
- COMPARATIVE POTENCIES OF ESMOLOL, A SHORT-ACTING BETA-BLOCKER, AND PROPRANOLOL IN MAN (1984) (3)
- Drug interactions with Ethmozine (moricizine HCl). (1987) (3)
- Acute Effects of Halothane Anesthesia on Arterial and Venous Concentrations of Propranolol in the Dog (1987) (3)
- Coadministration of glyburide and minoxidil, drugs with opposing effects on potassium channels (1997) (3)
- Beta-adrenergic receptor properties of a pulmonary alveolar type II cell preparation from the adult rat (2007) (3)
- A POTENT INHIBITOR OF BOTH P-GLYCOPROTEIN AND CYP 3 A IN VITRO (2000) (3)
- A qualitative analysis of pulsatile perfusion: effects on cortisol response to cardiopulmonary bypass surgery. (1986) (3)
- Alpha 2-Adrenergic Receptor – Induced Vascular Constriction in Blacks and Whites (2003) (3)
- THE EFFECT OF AGE ON THE ADRENERGIC RESPONSE TO ENDOTRACHEAL INTUBATION (1987) (3)
- The α2C-adrenoceptor deletion322–325 variant and cold-induced vasoconstriction (2009) (3)
- Altered beta-adrenoceptor internalization does not explain reduced beta-adrenergic responsiveness in the elderly. (1989) (3)
- Mechanisms for interethnic differences in antihypertensive drug response. (1995) (2)
- Identification and Functional Characterization of a New CYP 2 C 9 Variant ( CYP 2 C 9 * 51 ) Expressed among African Americans (2001) (2)
- HALOTHANEINHIBITS PRESYNAPTIC β2-INDUCED NOREPINEPHRINE (NE) RELEASE IN VIVO (1992) (2)
- Attenuation of Isoproterenol-Mediated Vasodilatation in Blacks: response from authors. (1995) (2)
- 2301 – AGE RELATED EFFECTS OF SMOKING ON ELIMINATION OF PROPRANOLOL (P) ANTIPYRINE (Ap) AND INDOCYANINE GREEN (ICG) (1978) (2)
- THE EFFECT OF HALOTHANE ON DRUG DISPOSITION: CONTRIBUTIONS OF HEPATIC METABOLISM AND BLOOD FLOW (1984) (2)
- EFFECTS OF PROPOFOL ON DRUG DISPOSITION: MARKED EFFECTS ON DRUG DISTRIBUTION, LESS EFFECT ON DRUG METABOLISM (1988) (2)
- THE EFFECT OF FENTANYL-ANESTHESIA ON DRUG DISPOSITION (1985) (2)
- G-protein β-3 subunit 825C/T polymorphism is associated with weight gain in pregnancy but not with preeclampsia (2001) (2)
- Cyclosporine pharmacokinetics and pharmacodynamics in African‐Americans (AA) and Caucasians (C) (1999) (2)
- Sympathetic activation in the elderly: is it due to impaired alpha adrenergic feedback sympathoinhibition? (1997) (1)
- TIMOLOL MALEATE—A PROMISING NEW BETA ADRENERGIC BLOCKER FOR GLAUCOMA (1979) (1)
- Co‐Administration of Glyburide and Minoxidil, Drugs with Opposing Effects on Potassium Channels (1996) (1)
- Leukocyte :-Receptor Alterations in Hypertensive Subjects (2013) (1)
- Beta receptor sensitivity testing in humans. (1987) (1)
- HALOTHANE–INDUCED HEPATIC NECROSIS IN HYPERTHYROID RATS (1979) (1)
- Assessment of β-Adrenoceptor down Regulation in Man (1980) (1)
- 2687 – REDUCED β-ADRENOCEPTOR SENSITIVITY IN THE ELDERLY (1978) (1)
- A Polymorphism of the Endothelial Nitric Oxide Synthase Gene is Associated with Pre-eclampsia A12 (2000) (1)
- Disproportionate Decrease in-Compared With -Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation (2002) (1)
- HALOTHANE ANESTHESIA HAS NO EFFECT ON THE M-3-GLUCURONIDATION OF MORPHINE (1987) (1)
- The Effect of Inhibition of Prosta-Glandin Synthesis on Hepatic Drug Clearance (1982) (1)
- Use of N-ethylmaleimide to directly determine the proportion of beta-adrenergic receptors exhibiting high affinity for agonists on human mononuclear leukocyte membranes. (1989) (1)
- Beta‐2 Adrenergic Receptor (BAR2) Poly‐morphism is Not Associated with Essential Hypertension (HT) in African‐Americans (AA) or Caucasian‐Americans (CA) (1999) (1)
- Pharmacokinetics and Pharmacodynamics of Beta-Blockers (1982) (1)
- Levodopa and positive direct antiglobulin tests. (1975) (1)
- Effect of alpha‐2C adrenergic receptor (ADRA2C) 322–325 deletion polymorphism on blood pressure response to dietary sodium in African‐Americans (AA) (2004) (0)
- RELATIVE CONTRIBUTIONS OF LIVER AND KIDNEY TO MORPHINE DISPOSITION (1986) (0)
- Room I, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Association of a Polymorphism of the β2Adrenergic Receptor with Pre-Eclampsia in a Hispanic Population A-1053 (2000) (0)
- Changes in Responses to Drugs Acting on Beta Receptors in Aging (1987) (0)
- Room I, 10/17/2000 9: 00 AM - 11: 00 AM (PS) A Polymorphism of the Endothelial Nitric Oxide Synthase Gene Is Associated with Pre-Eclampsia A-1080 (2000) (0)
- Endothelial nitric oxide synthase GLU298ASP polymorphism and blood pressure responses to salt (2003) (0)
- EXCESSIVE BETA -BLOCKADE WITH TIMOLOL EYE DROPS. AUTHORS' REPLY (1996) (0)
- Loperamide causes respiratory depression when P‐gp is inhibited (1999) (0)
- OIII‐B‐3 (2006) (0)
- after cessation of prostacyclin infusion in sheep Angiotensin II mediates systemic rebound hypertension (2015) (0)
- Reduction of catheter-associated sepsis in parenteral nutrition using heparin. (1979) (0)
- Association of the Glu298Asp Polymorphism of the Endothelial Nitric Oxide Synthase Gene with Preterm Labor A13 (2000) (0)
- Beta‐2 adrenergic receptor polymorphisms and blood pressure responses to salt (2004) (0)
- A591 DUAL ACTION OF HALOTHANE ON SYMPATHETIC FUNCTIONDECREASE IN NE RELEASE AND CLEARANCE (1990) (0)
- CONTRASTING EFFECTS OF INHALATIONAL ANESTHETICS ON IN VIVO DRUG METABOLISM (1982) (0)
- 2897 – THE INFLUENCE OF CIRRHOSIS ON FREE PROPRANOLOL CONCENTRATION DURING CHRONIC ORAL ADMINISTRATION (1978) (0)
- Nitroglycerin Use During Placebo and Propranolol Trial Placebo Low High Placebo (0)
- Alpha‐2B adrenergic receptor (ADRA2B) 301‐303 deletion polymorphism and vascular desensitization in vivo (2004) (0)
- A 9‐base pair deletion polymorphism in the alpha2B‐adrenergic receptor gene (ADRA2B) is not associated with pre‐eclampsia or pre‐term labor (2003) (0)
- A search for the genomic basis for inter‐individual variability in alpha1a‐adrenergic receptor response (2003) (0)
- EFFECTS OF PROPOFOL ON Literature ReviewMARKED EFFECTS ON DRUG DISTRIBUTION, LESS EFFECT ON DRUG METABOLISM (1988) (0)
- Ethnic variability in the frequency of alpha2B‐adrenergic receptor gene (ADRA2B) polymorphism (2003) (0)
- Effects of erythromycin on sufentanil liver metabolism and hepatic clearance. Difference between in vitro and in vivo. (1996) (0)
- Propranolol in the treatment of cardiovascular disease. (1978) (0)
- ASSOCIATION OF THE G-PROTEIN β-3 SUBUNIT 825C/T POLYMORPHISM AND WEIGHT GAIN IN PREGNANCY A49 (Poster 39) (2001) (0)
- A rapid pharmacodynamic measure to determine interindividual variability in response to cyclosporine (1999) (0)
- β-Blocker Withdrawal (1983) (0)
- EFFECT OF CIMETIDINE ON THE OXIDATIVE METABOLISM OF HALOTHANE (1984) (0)
- THE EFFECT OF HALOTHANE ON Literature ReviewCONTRIBUTIONS OF HEPATIC METABOLISM AND BLOOD FLOW (1984) (0)
- Alpha2 adrenergic receptor‐mediated vascular responses in African Americans and Caucasians (2003) (0)
- Decreased Vascular Response To Phenylephrine In Pregnancy A17 (2000) (0)
- Effects of Epinephrine on Norepinephrine Release (1996) (0)
- Effect of alpha2b adrenergic receptor 301–303 deletion polymorphism on blood pressure response to dietary sodium (2003) (0)
- 47 The value of different humoral correlates in assessing the blockade of angiotensin II generation by the angiotensin converting enzyme inhibitor CS 622 (1993) (0)
- Alpha‐2C adrenergic receptor (ADRA2C) 322‐325 deletion polymorphism and in vivo vascular sensitivity (2004) (0)
- HALOTHANE INHIBITION OF DRUG METABOLISM IS STEREOSELECTIVE (1988) (0)
- Ethnicity And Systemic Effects Of Dexmedetomidine, A Specific Adrenergic α: Piii-8-receptor Agonist: Piii-8 (2006) (0)
- Interaction of Cimetidine and Alcohol-Reply (1983) (0)
- Sequence analysis of the α2B‐ADRENERGIC receptor (ADRA2B) gene and in‐vivo functional effects of novel variants (2005) (0)
- Blunted Blood Pressure Response to Central Sympatho‐Inhibition in Blacks (1996) (0)
- The selective alpha2‐adrenergic receptor agonist dexmedetomidine (DEX) does not affect aortic pressure augmentation (2005) (0)
- Increased α1 Adrenergic Vascular Sensitivity in The Dorsal Hand Vein in African‐Americans (2003) (0)
- Room I, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Association of the Argl6Gly Polymorphism of the β2Adrenergic Receptor with Preterm Labor in a Hispanic Population A-1052 (2000) (0)
- Regulation of alpha2 adrenergic vascular responses in vivo (2003) (0)
- Excessive β-Blockade With Timolol Eye Drops-Reply (1996) (0)
- Adenylate cyclase type 9 (AC9) polymorphism and in vivo vascular response (2005) (0)
- EFFECTS OF PROPOFOL ON DRUG DISPOSITION (1988) (0)
- PI‐28 (2006) (0)
- Differences in the frequency of Arg492⇒Cys polymorphism of the human α1A‐adrenergic receptor (α1A‐AR) in African‐Americans (AA) and Caucasians (CA) (1999) (0)
- effects bi: pinacidil disposition and (1986) (0)
- Interethnic Differences in Beta‐2 Adrenoceptor (BAR2) Polymorphisms in African‐American (AA), Caucasian (CA), and Chinese (CHN) Populations (1999) (0)
- A common polymorphism in the adenylyl cyclase type 9 (AC9) gene does not alter vascular responses to isoproterenol (2004) (0)
- Adrenergic responses in post‐menopausal women: No evidence of modulation by estrogen (1999) (0)
- Identification of a new beta1‐adrenergic receptor variant VAL5ALA more frequent in African‐Americans (2003) (0)
- THE EFFECT OF HALOTHANE ANESTHESIA ON MORPHINE DISPOSITION (1986) (0)
- CYP2A6 genetic variation and dexmedetomidine disposition (2012) (0)
- Vascular Response To Isoproterenol In Pregnancy A33 (2000) (0)
- CYP3A inhibition increases plasma levels of vernarinone in humans (1997) (0)
- Association of the Arg16Gly Polymorphism of the β2Adrenergic Receptor with Preterm Labor A6 (2000) (0)
- PIII‐8 (2006) (0)
- Room I, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Association of the Glu298Asp Polymorphism of the Endothelial Nitric Oxide Synthase Gene with Preterm Labor A-1054 (2000) (0)
- Association of a Polymorphism of the Beta-2 Adrenergic Receptor with Pre-eclampsia A41 (2000) (0)
- DIRECTMEASUREMENTOF PROPRANOLOLBIOAVAILABILITY DURINGACCUMULATIONTO STEADY-STATE (1978) (0)
- &agr;2B Adrenergic receptor 301–303 deletion polymorphism and vascular &agr;2 adrenergic receptor response (2005) (0)
- Chinese are more sensitive to renin suppression by propranolol and to anticholinergic effects of atropine (1990) (0)
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