Arthur David Karlin
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Arthur David Karlinphysics Degrees
Physics
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Arthur David Karlinbiology Degrees
Biology
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Molecular Biology
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Physics Biology
Arthur David Karlin's Degrees
- PhD Biophysics University of California, Berkeley
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(Suggest an Edit or Addition)Arthur David Karlin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Acetylcholine receptor channel structure probed in cysteine-substitution mutants. (1992) (635)
- Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins (1995) (627)
- Substituted-cysteine accessibility method. (1998) (516)
- Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit (1994) (423)
- Ion channel structure: Emerging structure of the Nicotinic Acetylcholine receptors (2002) (419)
- Functional contributions of α5 subunit to neuronal acetylcholine receptor channels (1996) (398)
- On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine. (1967) (386)
- Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site. (1984) (349)
- Nicotinic acetylcholine receptors. (1977) (345)
- Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues. (1986) (343)
- Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica. (1978) (328)
- Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates. (1994) (245)
- Structure of the NMDA Receptor Channel M2 Segment Inferred from the Accessibility of Substituted Cysteines (1996) (242)
- Structure of nicotinic acetylcholine receptors (1993) (232)
- Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment (2001) (220)
- Affinity-labeling of purified acetylcholine receptor from Torpedo californica. (1974) (213)
- Chemical Modification of the Active Site of the Acetylcholine Receptor (1969) (208)
- Effects of blocking sulfhydryl groups and of reducing disulfide bonds on the acetylcholine-activated permeability system of the electroplax. (1966) (207)
- The Location of the Gate in the Acetylcholine Receptor Channel (1998) (195)
- Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method (1995) (158)
- Identification of acetylcholine receptor channel-lining residues in the M1 segment of the beta-subunit. (1995) (149)
- Reduction and specific alkylation of the receptor for acetylcholine. (1968) (144)
- Bromoacetylcholine as an affinity label of the acetylcholine receptor from Torpedo californica. (1978) (131)
- Affinity labeling of one of two alpha-neurotoxin binding sites in acetylcholine receptor from Torpedo californica. (1978) (131)
- A critical concentration of neutrophils is required for effective bacterial killing in suspension (2002) (129)
- Exposure of Residues in the Cyclic Nucleotide–Gated Channel Pore: P Region Structure and Function in Gating (1996) (125)
- Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method. (2001) (120)
- Facets of the structures of acetylcholine receptors from Electrophorus and Torpedo. (1976) (120)
- The affinity-labeling of partially purified acetylcholine receptor from electric tissue of Electrophorus. (1973) (117)
- Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine. (1993) (114)
- State-dependent Accessibility and Electrostatic Potential in the Channel of the Acetylcholine Receptor (1998) (112)
- Acetylcholine Receptor: Covalent Attachment of Depolarizing Groups at the Active Site (1969) (110)
- Explorations of the nicotinic acetylcholine receptor. (1989) (109)
- Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins (2020) (105)
- Formation of disulfide-linked oligomers of acetylcholine receptor in membrane from torpedo electric tissue. (1979) (101)
- The arrangement of the subunits of the acetylcholine receptor of Torpedo californica. (1983) (95)
- The acetylcholine receptor: progress report. (1974) (91)
- Structure of the Nicotinic Receptor Acetylcholine-binding Site (1995) (89)
- Location of KCNE1 relative to KCNQ1 in the IKS potassium channel by disulfide cross-linking of substituted cysteines (2009) (83)
- Disulfide bond cross-linked dimer in acetylcholine receptor from Torpedo californica. (1977) (76)
- Effect of local pH changes caused by substrate hydrolysis on the activity of membrane-bound acetylcholinesterase. (1967) (70)
- Agonist binding site of Torpedo electric tissue nicotinic acetylcholine receptor. A negatively charged region of the delta subunit within 0.9 nm of the alpha subunit binding site disulfide. (1991) (69)
- Locations of the β1 transmembrane helices in the BK potassium channel (2008) (68)
- The sidedness of the COOH terminus of the acetylcholine receptor delta subunit. (1989) (67)
- Unraveling the mechanism of the lactose permease of Escherichia coli. (2000) (66)
- Mapping the alpha-subunit site photolabeled by the noncompetitive inhibitor [3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor. (1990) (66)
- Determination of the Critical Concentration of Neutrophils Required to Block Bacterial Growth in Tissues (2004) (66)
- Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor. (1998) (64)
- Affinity labeling of the acetylcholine receptor in the electroplax: electrophoretic separtion in sodium dodecyl sulfate. (1972) (64)
- Location of modulatory β subunits in BK potassium channels (2010) (62)
- Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit. (1995) (61)
- Position and Role of the BK Channel α Subunit S0 Helix Inferred from Disulfide Crosslinking (2008) (61)
- An analysis by low-angle neutron scattering of the structure of the acetylcholine receptor from Torpedo californica in detergent solution. (1979) (60)
- Affinity labeling of the acetylcholine receptor in the electroplax. (1971) (59)
- Molecular pharmacology of the nicotinic acetylcholine receptor (1986) (56)
- The Contributions of Aspartyl Residues in the Acetylcholine Receptor γ and δ Subunits to the Binding of Agonists and Competitive Antagonists* (1996) (55)
- The Intrinsic Electrostatic Potential and the Intermediate Ring of Charge in the Acetylcholine Receptor Channel (2000) (53)
- THE ASSOCIATION OF ACETYLCHOLINESTERASE AND MEMBRANE IN SUBCELLULAR FRACTIONS OF THE ELECTRIC TISSUE OF ELECTROPHORUS (1965) (48)
- Time-resolved photolabeling by quinacrine azide of a noncompetitive inhibitor site of the nicotinic acetylcholine receptor in a transient, agonist-induced state. (1985) (47)
- Electron microscopy of complexes of isolated acetylcholine receptor, biotinyl-toxin, and avidin. (1982) (46)
- Affinity alkylation labels two subunits of the reduced acetylcholine receptor from mammalian muscle. (1977) (44)
- Location of the β4 Transmembrane Helices in the BK Potassium Channel (2009) (44)
- Binding of antibodies to acetylcholine receptors in Electrophorus and Torpedo electroplax membranes (1978) (44)
- Effects of agonists and antagonists on the reactivity of the binding site disulfide in acetylcholine receptor from Torpedo californica. (1980) (43)
- Delimiting the Binding Site for Quaternary Ammonium Lidocaine Derivatives in the Acetylcholine Receptor Channel (1998) (40)
- Photoaffinity labeling of the epithelial sodium channel. (1986) (40)
- Chemical distinctions between acetylcholinesterase and the acetylcholine receptor. (1967) (40)
- The arrangement and functions of the chains of the acetylcholine receptor of Torpedo electric tissue. (1983) (37)
- Relative locations of the beta and delta chains of the acetylcholine receptor determined by electron microscopy of isolated receptor trimer. (1981) (36)
- Reaction of quinacrine mustard with the acetylcholine receptor from Torpedo californica. (1983) (35)
- Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1 (2012) (34)
- Locations Of The Beta2 Transmembrane Helices In The BK Potassium Channel (2009) (32)
- Molecular interactions of the acetylcholine receptor. (1973) (28)
- PURIFICATION OF ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA AND ITS INCORPORATION INTO PHOSPHOLIPID VESICLES fn1 (1975) (28)
- Functional Domains of the Nicotinic Acetylcholine Receptor a (1986) (27)
- Positions of β2 and β3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel (2013) (26)
- Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides (2002) (24)
- Permeability and internal concentration of ions during depolarization of the electroplax. (1967) (23)
- Structure of acetylcholine receptor dimer determined by neutron scattering and electron microscopy. (1981) (22)
- The in vitro release by the toad bladder of an inhibitor of oxytocin. (1963) (21)
- A continuous-flow, rapid-mixing, photolabeling technique applied to the acetylcholine receptor. (1984) (20)
- Binding of a curarimimetic toxin from cobra venom to the nicotinic acetylcholine receptor. Interactions of six biotinyltoxin derivatives with receptor and avidin. (1985) (20)
- Structural effects of quinacrine binding in the open channel of the acetylcholine receptor (2003) (19)
- Assay of the acetylcholine receptor by affinity labeling. (1976) (18)
- Functional effects on the acetylcholine receptor of multiple mutations of gamma Asp174 and delta Asp180. (1997) (18)
- Purification and reconstitution of nicotinic acetylcholine receptor. (1992) (18)
- Affinity oxidation of the reduced acetylcholine receptor. (1970) (17)
- [68] Nicotinic acetylcholine receptors☆ (1977) (17)
- A Touching Picture of Nicotinic Binding (2004) (15)
- ISOLATION AND PROPERTIES OF ACETYLCHOLINE RECEPTORS FROM ELECTROPHORUS AND TORPEDO * (1976) (14)
- Functional sites and transient states of the nicotinic acetylcholine receptor. (1987) (14)
- Orientations and Proximities of the Extracellular Ends of Transmembrane Helices S0 and S4 in Open and Closed BK Potassium Channels (2013) (13)
- Action of antibiotics affecting membrane permeability on the electroplax. (1968) (11)
- Scam Feels the Pinch (2001) (10)
- Molecular Properties of the Acetylcholine Receptor (1973) (10)
- Interactions of a cobra neurotoxin and affinity labels of the acetylcholine receptor in the electroplax. (1972) (10)
- Positions of the cytoplasmic end of BK α S0 helix relative to S1–S6 and of β1 TM1 and TM2 relative to S0–S6 (2015) (9)
- An Inhibitor of Oxytocin from the Urinary Bladder of the Toad, Bufo marinus (1965) (8)
- Counting acetylcholine receptors in the electroplax. In: Molecular properties of drug receptors. (2008) (8)
- Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response (2022) (7)
- Acetylcholine receptors in and out of membranes. (1979) (7)
- The intactness and orientation of acetylcholine receptor-rich membrane from Torpedo californica electric tissue. (1989) (7)
- Nicotinic Acetylcholine Receptor: Secondary Structure Determined by Circular Dichroism Spectroscopy a (1986) (7)
- Transfer in SDS of biotinylated proteins from acrylamide gels to an avidin-coated membrane filter. (2004) (6)
- Voltage fluctuations at the frog sartorius motor endplate produced by a covalently attached activator (1979) (5)
- Membrane potential and Ca2+ concentration dependence on pressure and vasoactive agents in arterial smooth muscle: A model (2015) (5)
- Position and Role of the BK Channel (cid:2) Subunit S0 Helix Inferred from Disulfi de Crosslinking (2008) (5)
- Characterization of KCNQ 1 atrial fibrillation mutations reveals distinct dependence on KCNE 1 (2012) (5)
- Transport bicycles. (1997) (4)
- Further Characterization of Purified Acetylcholine Receptor and its Incorporation into Phospholipid Vesicles (1975) (4)
- Acetylcholine Receptors: Approaches to the Mechanism of Permeability Control (1976) (4)
- Structures involved in binding, gating, and conduction in nicotinic acetylcholine receptors. (1994) (3)
- Chemical Modification of the of the Acetylcholine Receptor Active Site (1969) (3)
- A photochemical approach to the lipid accessibility of engineered cysteinyl residues (2003) (3)
- Of Snakes, Snails, and Surrogates (2001) (2)
- Activation of the frog sartorius acetylcholine receptor by a covalently attached group (1979) (2)
- Interactions among binding sites on acetylcholine receptors in membrane and in detergent solution. (1978) (2)
- Binding and Gating by the Acetylcholine Receptor (1975) (2)
- THE ACETYLCHOLINE RECEPTOR: PROGRESS REPORT (1975) (2)
- Positions of the cytoplasmic end of BK S 0 helix relative to S 1 – S 6 and of 1 TM 1 and TM 2 relative to S 0 – S 6 (1)
- Future Directions in Sodium Channel Research (1986) (1)
- Mapping the Ryanodine Receptors Pore Region Using the Substituted Cysteine Accessibility Method (2009) (0)
- Neighboring Alpha-Subunit (KCNQ1) Mutations with a Gain-of-Function IKs Phenotype Show Differential Dependence on Presence of Beta-Subunit (KCNE1) (2010) (0)
- CHAPTER 39 – Nicotinic Acetylcholine Receptors (2003) (0)
- Functional sites of the nicotinic acetylcholine receptor. (1988) (0)
- Cryo-EM structure of Torpedo acetylcholine receptor in complex with alpha-bungarotoxin (2020) (0)
- Disulfide Crosslinking Between BK Channel Alpha And Beta1 Subunits In The Membrane Domain (2009) (0)
- The Locations of the Beta4 Transmembrane Helices in the BK Channel (2009) (0)
- An Inquiry Into the Psychological and Philosophical Antecedents of An Asset Concept (1964) (0)
- Affinity Labeling oftheAcetylcholine Receptor intheElectroplax: Electrophoretic Separation inSodiumDodecyl Sulfate (1972) (0)
- DEPOLARIZATION OF THE ELECTROPLAX (2016) (0)
- Beta Subunits Bridge Two Alpha Subunits Within the BK Channel Tetramer (2010) (0)
- Nicotinic acetylcholine receptors: probing functionally significant structural changes with site-directed reactions (2004) (0)
- The channel and the gate in the acetylcholine receptor (1997) (0)
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