Allen M. Spiegel

Q: What Schools Are Affiliated With Allen M. Spiegel

Allen M. Spiegel is affiliated with the following schools: University of California, San Diego, University of Oklahoma, Yeshiva University

Allen M. Spiegel's AcademicInfluence.com Rankings

Allen M. Spiegel

Philosophy

#5181

World Rank

#7917

Historical Rank

Logic

#2500

World Rank

#3504

Historical Rank

philosophy Degrees

Allen M. Spiegel

Biology

#6930

World Rank

#9749

Historical Rank

Endocrinology

#67

World Rank

#77

Historical Rank

Genetics

#656

World Rank

#740

Historical Rank

Molecular Biology

#757

World Rank

#774

Historical Rank

biology Degrees

Download Badge

Philosophy
Biology

Why Is Allen M. Spiegel Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Allen M. Spiegel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Positional cloning of the gene for multiple endocrine neoplasia-type 1. (1997) (1906)
Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. (1991) (1502)
Menin Interacts with the AP1 Transcription Factor JunD and Represses JunD-Activated Transcription (1999) (627)
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. (1997) (461)
Menin, the product of the MEN1 gene, is a nuclear protein. (1998) (435)
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. (2001) (434)
The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. (1991) (334)
Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction. (1992) (327)
Human cDNA clones for four species of G alpha s signal transduction protein. (1986) (318)
Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas. (1997) (305)
Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. (1993) (292)
Resistance to multiple hormones in patients with pseudohypoparathyroidism. Association with deficient activity of guanine nucleotide regulatory protein. (1983) (287)
Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain. (1987) (283)
Signal transduction by guanine nucleotide binding proteins (1987) (283)
Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. (1997) (281)
Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies. (1989) (280)
The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gsα gene: site‐specific patterns and recurrent histological hallmarks (1999) (249)
Mutations of the Gs alpha-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis. (1990) (246)
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung. (1997) (238)
Deficient activity of guanine nucleotide regulatory protein in erythrocytes from patients with pseudohypoparathyroidism. (1980) (237)
Mutations of the MEN1 tumor suppressor gene in pituitary tumors. (1997) (235)
Inherited diseases involving g proteins and g protein-coupled receptors. (2004) (233)
A prospective trial evaluating a standard approach to reoperation for missed parathyroid adenoma. (1996) (232)
Mutations of the GNAS1 Gene, Stromal Cell Dysfunction, and Osteomalacic Changes in Non–McCune–Albright Fibrous Dysplasia of Bone (2000) (231)
Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout (2003) (229)
Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation. (1997) (228)
Defects in G protein-coupled signal transduction in human disease. (1996) (227)
The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation (2001) (223)
An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. (1994) (222)
Genome-Wide Analysis of Menin Binding Provides Insights into MEN1 Tumorigenesis (2006) (211)
Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells. (1998) (208)
Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes (1987) (202)
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation. (1994) (192)
Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. (1983) (188)
Multiple endocrine neoplasia type 1: new clinical and basic findings (2001) (187)
Identification of the Cysteine Residues in the Amino-terminal Extracellular Domain of the Human Ca2+ Receptor Critical for Dimerization (1999) (186)
Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent. (1998) (176)
Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias. (1999) (171)
An association between neonatal severe primary hyperparathyroidism and familial hypocalciuric hypercalcemia in three kindreds. (1982) (170)
G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain. (1991) (169)
Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment. (1990) (165)
Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors. (1997) (165)
Increased palmitoylation of the Gs protein alpha subunit after activation by the beta-adrenergic receptor or cholera toxin. (1993) (159)
Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. (1985) (158)
Receptor and effector interactions of Gs Functional studies with antibodies to the αs carboxyl‐terminal decapeptide (1989) (156)
Mutations in G proteins and G protein-coupled receptors in endocrine disease. (1996) (154)
Identification of the Sites of N-Linked Glycosylation on the Human Calcium Receptor and Assessment of Their Role in Cell Surface Expression and Signal Transduction* (1998) (152)
Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. (1986) (151)
Calcium-regulated parathyroid hormone release in primary hyperparathyroidism: studies in vitro with dispersed parathyroid cells. (1979) (150)
Molecular Pathology of the MEN1 Gene (2004) (148)
Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system. (1990) (139)
Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients. (1996) (137)
Hyperparathyroidism in hereditary syndromes: special expressions and special managements. (2002) (133)
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter (2003) (130)
Activity of the stimulatory guanine nucleotide-binding protein is reduced in erythrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds. (1986) (129)
Menin molecular interactions: insights into normal functions and tumorigenesis. (2005) (129)
Identification of the GTP-binding protein encoded by Gi3 complementary DNA. (1988) (129)
The 32-Kilodalton Subunit of Replication Protein A Interacts with Menin, the Product of the MEN1 Tumor Suppressor Gene (2003) (128)
Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators (2007) (128)
Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism. (1999) (128)
Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go. (1988) (127)
Abnormalities in G protein-coupled signal transduction pathways in human disease. (1993) (127)
The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. (1987) (127)
Divalent cation metabolism. Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. (1978) (126)
Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1. (1986) (126)
A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. (1997) (126)
Loss of heterozygosity at 11q13: analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1. (1997) (126)
Use of specific antibodies to quantitate the guanine nucleotide-binding protein Go in brain. (1986) (125)
Antisera against a guanine nucleotide binding protein from retina cross-react with the beta subunit of the adenylyl cyclase-associated guanine nucleotide binding proteins, Ns and Ni. (1985) (124)
Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas vs. primary hyperplasia. (1978) (124)
The Carboxyl Terminus of the Human Calcium Receptor (1997) (122)
A familial syndrome of decrease in sensitivity to 1,25-dihydroxyvitamin D. (1978) (121)
Familial hypocalciuric hypercalcemia: recognition among patients referred after unsuccessful parathyroid exploration. (1980) (121)
Common ancestral mutations in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland (1998) (121)
Clinical implications of guanine nucleotide-binding proteins as receptor-effector couplers. (1985) (120)
Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods. (1987) (119)
Receptor-effector coupling by G proteins (1990) (118)
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. (2001) (117)
Family studies in patients with primary parathyroid hyperplasia. (1977) (115)
Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein. (1980) (115)
Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor. (2007) (113)
Maximal urine-concentrating ability: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. (1981) (113)
Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. (1986) (110)
Stable overexpression of MEN1 suppresses tumorigenicity of RAS (1999) (109)
Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function (2003) (108)
Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells. (1991) (108)
Allelic loss from chromosome 11 in parathyroid tumors. (1992) (107)
Bidirectional transcriptional activity of PGK‐neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice (2001) (106)
Guanine nucleotides: key regulators of hormone receptor-adenylate cyclase interaction. (1981) (106)
MEN1 gene analysis in sporadic adrenocortical neoplasms. (1999) (105)
Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C. (1986) (104)
Mediation of growth factor induced DNA synthesis and calcium mobilization by Gq and Gi2 (1993) (104)
A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy. (1992) (104)
Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas. (2000) (101)
Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation. (1994) (101)
Sporadic hypoparathyroidism caused by de Novo gain-of-function mutations of the Ca(2+)-sensing receptor. (1997) (100)
alpha-Transducin immunoreactivity in retinae and sensory pineal organs of adult vertebrates. (1986) (98)
Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. (2003) (98)
Lipopolysaccharide response is linked to the GTP binding protein, Gi2, in the promonocytic cell line U937. (1989) (97)
Familial hypocalciuric hypercalcemia: the relation to primary parathyroid hyperplasia. (1982) (97)
Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction (1998) (96)
The G protein connection: molecular basis of membrane association. (1991) (94)
Human Ca2+ Receptor Cysteine-rich Domain (2000) (93)
The G protein alpha s subunit incorporates [3H]palmitic acid and mutation of cysteine-3 prevents this modification. (1993) (93)
G proteins couple alpha-adrenergic and GABAb receptors to inhibition of peptide secretion from peripheral sensory neurons (1989) (91)
Identification of Acidic Residues in the Extracellular Loops of the Seven-transmembrane Domain of the Human Ca2+ Receptor Critical for Response to Ca2+ and a Positive Allosteric Modulator* (2002) (89)
Aspiration of enlarged parathyroid glands for parathyroid hormone assay. (1983) (89)
Purification and immunochemical characterization of the major pertussis-toxin-sensitive guanine-nucleotide-binding protein of bovine-neutrophil membranes. (1987) (89)
A Region in the Seven-transmembrane Domain of the Human Ca2+ Receptor Critical for Response to Ca2+* (2005) (86)
The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations. (2007) (84)
Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors. (2000) (83)
Deficient guanine nucleotide regulatory unit activity in cultured fibroblast membranes from patients with pseudohypoparathyroidism type I. a cause of impaired synthesis of 3',5'-cyclic AMP by intact and broken cells. (1983) (80)
MEN1 gene mutation analysis of high‐grade neuroendocrine lung carcinoma (2000) (79)
Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain. (1987) (78)
Genetic abnormalities in sporadic parathyroid adenomas. (1990) (78)
Binding of 5'-guanylyl-imidodiphosphate to turkey erythrocyte membranes and effects on beta-adrenergic-activated adenylate cyclase. (1974) (78)
Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. (1991) (77)
Neonatal primary hyperparathyroidism with autosomal dominant inheritance. (1977) (77)
Technetium-99m-sestamibi imaging before reoperation for primary hyperparathyroidism. (1995) (77)
Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis. (1991) (74)
Direct comparison in vivo and in vitro of suppressibility of parathyroid function by calcium in primary hyperparathyroidism. (1979) (74)
N-linked glycosylation of the human Ca2+ receptor is essential for its expression at the cell surface. (1997) (74)
Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrotropin-releasing hormone receptor genes. (1996) (73)
Reoperative parathyroid surgery for persistent hyperparathyroidism. (1978) (71)
Evidence for direct interaction of Gs alpha with the Ca2+ channel of skeletal muscle. (1991) (71)
Human cDNA clones for an alpha subunit of Gi signal-transduction protein. (1987) (70)
Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia. (1987) (70)
Immunological and molecular characterization of Go alpha-like proteins in the Drosophila central nervous system. (1989) (70)
Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. (1992) (70)
Functional characterization of five V2 vasopressin receptor gene mutations (1996) (69)
Antibodies against the carboxyl-terminal 5-kDa peptide of the alpha subunit of transducin crossreact with the 40-kDa but not the 39-kDa guanine nucleotide binding protein from brain. (1985) (68)
Detection of multiple forms of Giα in HL60 cells (1987) (67)
Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis. (1997) (65)
Osteoblastic cells derived fronm isolated lesions of fibrous dysplasia contain activating somatic mutatuions of thje Gsα gene (1995) (65)
Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1. (2009) (65)
Heterogeneous size of the parathyroid glands in familial multiple endocrine neoplasia type 1 (1991) (64)
Expression, Purification, and Biochemical Characterization of the Amino-terminal Extracellular Domain of the Human Calcium Receptor* (1999) (64)
The molecular basis of disorders caused by defects in G proteins. (1997) (63)
G Proteins, Receptors, and Disease (1998) (62)
Olfactory dysfunction in humans with deficient guanine nucleotide-binding protein (1986) (62)
Subcellular localization of Gi alpha in human neutrophils. (1988) (61)
Immunolocalization of G protein alpha-subunits in the Drosophila CNS (1990) (61)
Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region (1997) (60)
Prospective evaluation of selective venous sampling for parathyroid hormone concentration in patients undergoing reoperations for primary hyperparathyroidism. (1993) (59)
Results of reoperation for persistent and recurrent hyperparathyroidism. (1981) (59)
The GTP-binding regulatory proteins of neuroblastoma x glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No. (1986) (59)
Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. (1987) (57)
Identification and persistence of beta adrenergic receptors during maturation of the rat reticulocyte. (1977) (57)
The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1) (2015) (57)
Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1 (2004) (57)
Multiple endocrine neoplasia type 1: atypical presentation, clinical course, and genetic analysis of multiple tumors. (1999) (56)
Localization of parathyroid adenomas in patients who have undergone surgery. Part II. Invasive procedures. (1987) (56)
Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. (1993) (55)
An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function. (1988) (53)
Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation. (2007) (53)
Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system. (1986) (52)
Autotransplantation of Cryopreserved Parathyroid Tissue in Man (1979) (52)
Antibodies which recognize the C-terminus of the inhibitory guanine-nucleotide-binding protein (Gi) demonstrate that opioid peptides and foetal-calf serum stimulate the high-affinity GTPase activity of two separate pertussis-toxin substrates. (1988) (52)
Circulating parathyroid hormone activity: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. (1978) (52)
Executive summary of the Strategic Plan for National Institutes of Health Obesity Research. (2005) (51)
Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion. (1980) (51)
Chemically induced hypothyroidism produces elevated amounts of the alpha subunit of the inhibitory guanine nucleotide binding protein (Gi) and the beta subunit common to all G-proteins. (1987) (50)
Parathyroid adenomas in the aortopulmonary window. (1996) (50)
Insulin-like growth factor I receptors in retinal rod outer segments. (1987) (50)
Deficient adenylate cyclase regulatory protein in renal membranes from a patient with pseudohypoparathyroidism. (1983) (50)
Signal transduction by guanine nucleotide-binding proteins. (1988) (49)
Selective deficiency of guanine nucleotide-binding protein Go in two dopamine-resistant pituitary tumors. (1988) (48)
Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies. (1992) (47)
Localization and operative management of undescended parathyroid adenomas in patients with persistent primary hyperparathyroidism. (1994) (47)
Monoclonal Antibodies Against Synthetic Peptides Corresponding to the Extracellular Domain of the Human Ca2+ Receptor: Characterization and Use in Studying Concanavalin A Inhibition (1997) (47)
Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. (1982) (47)
Angiographic ablation of parathyroid adenomas: lessons from a 10-year experience. (1987) (46)
Recurrent hyperparathyroidism from an autotransplanted parathyroid adenoma. (1978) (46)
G Protein Defects in Signal Transduction (2000) (46)
Expression of the calcium-sensing receptor in gastrinomas. (2000) (45)
Detection of alpha-transducin in retinal rods but not cones. (1986) (45)
A Missense Mutation in the Seven-transmembrane Domain of the Human Ca2+ Receptor Converts a Negative Allosteric Modulator into a Positive Allosteric Modulator* (2006) (44)
Characterization of a MEN1 ortholog from Drosophila melanogaster. (2001) (44)
A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13. (1997) (44)
Human Ca(2+) receptor extracellular domain. Analysis of function of lobe I loop deletion mutants. (2001) (42)
Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families (1998) (42)
Deferred parathyroid autografts with cryopreserved tissue after reoperative parathyroid surgery. (1982) (41)
Angiographic ablation of parathyroid adenomas. (1979) (40)
Use of preoperative fine-needle aspiration in patients undergoing reoperation for primary hyperparathyroidism. (1994) (39)
Treatment of hyperparathyroidism by percutaneous embolization of a mediastinal adenoma. (1975) (39)
Expression of G protein alpha-subunits in bovine parathyroid. (1995) (39)
Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development. (1987) (39)
Identification of G Protein α-Subunits in RINm5F Cells and Their Selective Interaction with Galanin Receptor (1991) (39)
Isolation, characterization, expression and functional analysis of the zebrafish ortholog of MEN1 (2000) (38)
G proteins in cellular control (1992) (37)
Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene. (1997) (37)
Locally recurrent parathyroid neoplasms as a cause for recurrent and persistent primary hyperparathyroidism. (1991) (36)
Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs. (1992) (36)
Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism. (1982) (36)
Parathyroid tumor development involves deregulation of homeobox genes. (2008) (35)
The gene for multiple endocrine neoplasia type 1: recent findings. (1999) (35)
GTP-binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini. (1987) (35)
G proteins in clinical medicine. (1988) (34)
Identification and characterization of JunD missense mutants that lack menin binding (2000) (33)
The localization of abnormal mediastinal parathyroid glands. (1975) (33)
Carboxyl methylation and COOH-terminal processing of the brain G-protein gamma-subunit. (1990) (33)
Hyperparathyroidism--a reversible cause of cimetidine-resistant gastric hypersecretion. (1979) (33)
Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. (1985) (33)
Albright's hereditary osteodystrophy and defective G proteins. (1990) (32)
Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders* (2016) (32)
Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism. (1982) (31)
Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride. (1982) (31)
Heterogeneous gland size in sporadic multiple gland parathyroid hyperplasia. (1999) (30)
Mutations of the Gs a-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis (29)
Beta-adrenergic receptors, cyclic AMP, and ion transport in the avian erythrocyte. (1975) (29)
Obesity on the brain (2005) (29)
The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte. (1977) (29)
Osteoblastic cells derived from isolated lesions of fibrous dysplasia contain activating somatic mutations of the Gs alpha gene. (1995) (29)
Molecular Cloning of Human Gαq cDNA and Chromosomal Localization of the Gαq Gene (GNAQ) and a Processed Pseudogene (1995) (29)
In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein. (1996) (28)
The detection of mediastinal parathyroid glands by computed tomography, selective arteriography, and venous sampling: an analysis of 17 cases. (1981) (28)
Adenosine 3',5'-monophosphate response to parathyroid hormone: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. (1980) (28)
Undescended parathyroid adenoma: An important etiology for failed operations for primary hyperparathyroidism (1990) (28)
Intrathyroidal parathyroid adenoma or hyperplasia. An occasionally overlooked cause of surgical failure in primary hyperparathyroidism. (1975) (28)
Differential expression of low molecular weight form of Gs-α in neostriatum and cerebellum: correlation with expression of calmodulin-independent adenylyl cyclase (1990) (27)
Novel mutations in the V2 vasopressin receptor gene of patients with X-linked nephrogenic diabetes insipidus. (1994) (27)
GTP analogues promote release of the alpha subunit of the guanine nucleotide binding protein, Gi2, from membranes of rat glioma C6 BU1 cells. (1988) (27)
Lithium does not inhibit the parathyroid hormone-mediated rise in urinary cyclic AMP and phosphate in humans. (1976) (27)
Hyperfunctioning cystic parathyroid glands: CT and sonographic findings. (1984) (26)
Diagnosis of radiosensitive hypothalamic tumors without craniotomy: endocrine and neuroradiologic studies of intracranial atypical teratomas. (1976) (26)
Human parathyroid autografts: comparison of function in vivo and in vitro. (1979) (26)
Site-specific antibodies directed against G protein beta and gamma subunits: effects on alpha and beta gamma subunit interaction. (1992) (26)
Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line. (1988) (26)
Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene (1999) (24)
Intraoperative measurements of urinary cyclic AMP to guide surgery for primary hyperparathyroidism. (1980) (24)
Pancreatic Insulinomas in Multiple Endocrine Neoplasia, Type I Knockout Mice Can Develop in the Absence of Chromosome Instability or Microsatellite Instability (2004) (24)
The effect of short term lithium administration on suppressibility of parathyroid hormone secretion by calcium in vivo. (1984) (24)
Myristoylation of an inhibitory GTP-binding protein a subunit is essential for its membrane attachment ( site-directed mutagenesis / immunoprecipitation / signal transduction / P 8-y subunits ) (24)
Immunoelectron microscopic localization of photoreceptor-specific markers in the monkey retina. (1987) (23)
Down-regulation of parathyroid (PTH)/PTH-related peptide receptor immunoreactivity and PTH binding in opossum kidney cells by PTH and dexamethasone. (1994) (23)
Antibodies against synthetic peptides as probes of G protein structure and function. (1990) (23)
Urinary cAMP excretion during surgery: an index of successful parathyroidectomy in patients with primary hyperparathyroidism. (1978) (23)
Hypercalcemia with suppressed parathyroid hormone in Burkitt's lymphoma. (1978) (22)
Receptor function and ion transport in turkey erythrocytes. (1976) (22)
Protein kinase C-mediated phosphorylation of retinal rod outer segment membrane proteins. (1989) (22)
CLINICAL ENDOCRINOLOGY & METABOLISM (1992) (21)
Regulation of guanine nucleotide binding regulatory proteins in cultured adrenal cells by adrenocorticotropin and angiotensin-II. (1991) (21)
'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: can it fulfill its promise? (2012) (21)
Pseudohypoparathyroidism: the molecular basis for hormone resistance--a retrospective. (1982) (20)
Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. (1984) (20)
Differential diagnosis of brown tumor vs. cystic osteitis by arteriography and computed tomography. (1979) (20)
The role of thyroid resection during reoperation for persistent or recurrent hyperparathyroidism. (1997) (20)
Differential distribution of signal-transducing G-proteins in retina (1987) (20)
Introduction to G-Protein-Coupled Signal Transduction and Human Disease (1998) (20)
Effects of chemical and enzymatic modifications of glucagon on its activation of hepatic adenyl cyclase. (1969) (19)
Isoprenylation of an inhibitory G protein alpha subunit occurs only upon mutagenesis of the carboxyl terminus. (1990) (19)
Inborn errors of signal transduction: Mutations in G proteins and G protein-coupled receptors as a cause of disease (1997) (19)
Immunoprecipitation of adenylate cyclase with an antibody to a carboxyl-terminal peptide from Gs alpha. (1990) (18)
Antiserum raised against residues 159-168 of the guanine nucleotide-binding protein Gi3-alpha reacts with ependymal cells and some neurons in the rat brain containing cholecystokinin- or cholecystokinin- and tyrosine 3-hydroxylase-like immunoreactivities. (1988) (18)
β-Arrestin--Not Just for G Protein-Coupled Receptors (2003) (18)
Amino- and carboxy-terminal deletion mutants of Gs alpha are localized to the particulate fraction of transfected COS cells (1992) (17)
Expression of GTP-binding proteins and prostaglandin E2 receptors during human T cell activation. (1991) (17)
Parathyroid adenoma within the vagus nerve. (1994) (17)
High level expression of transfected G protein αi3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts (1992) (17)
Computerized technetium/thallium scans and parathyroid reoperation. (1985) (17)
Intraoperative ultrasound and reoperative parathyroid surgery: An initial evaluation (1986) (17)
Parathymic parathyroid: CT, US, and angiographic findings. (1985) (16)
Hormone resistance caused by mutations in G proteins and G protein-coupled receptors. (1999) (16)
The inhibitory adenylate cyclase coupling protein in pseudohypoparathyroidism. (1985) (16)
Receptor-effector coupling by G-proteins implications for endocrinology (1989) (16)
Radiographic findings in recurrent parathyroid carcinoma. (1982) (16)
Functional interactions between the extracellular domain and the seven-transmembrane domain in Ca2+ receptor activation (2000) (15)
Antibodies as probes of G-protein receptor-effector coupling and of G-protein membrane attachment. (1990) (15)
Differential isoprenylation of carboxy-terminal mutants of an inhibitory G-protein alpha-subunit: neither farnesylation nor geranylgeranylation is sufficient for membrane attachment. (1992) (15)
Separation of a guanine nucleotide regulatory unit from the adenylate cyclase complex with GTP affinity chromatography. (1979) (15)
Immunochemical detection of guanine nucleotide binding proteins mono-ADP-ribosylated by bacterial toxins. (1986) (15)
Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene. (1995) (14)
Genetic interactions between Drosophila melanogaster menin and Jun/Fos. (2006) (14)
CHAPTER 6 – Immunologic Probes for Heterotrimeric GTP-Binding Proteins (1990) (14)
Mitogenic effects of pertussis toxin-sensitive G-protein α subunits: The mitogenic action of αi2 in NIH 3T3 cells is mimicked by αi1, but not αi3 (1993) (14)
Effects of parathormone and lithium treatment on calcium and mood in depressed patients. (1977) (14)
Membrane attachment of recombinant G-protein α-subunits in excess of βγ subunits in a eukaryotic expression system (1989) (13)
Guanosine 5′, α-β-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: Evidence against pyrophosphorylation mechanism (1977) (13)
Work in progress: abnormal parathyroid glands. Comparison of nonselective arterial digital arteriography, selective parathyroid arteriography, and venous digital arteriography as methods of detection. (1983) (13)
Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor (2001) (13)
Gland Size Is Associated With Changes in Gene Expression Profiles in Sporadic Parathyroid Adenomas (2004) (13)
11q13 allelotype analysis in 27 northern American MEN1 kindreds identifies two distinct founder chromosomes. (1998) (13)
High cervical intravagal hypercellular parathyroid gland as the etiology of severe persistent primary hyperparathyroidism. (1995) (12)
The use of anti-peptide antisera to probe interactions between receptors and guanine nucleotide binding proteins. (1988) (12)
Prospective analysis of intraoperative and postoperative urinary cyclic adenosine 3',5'-monophosphate levels to predict outcome of patients undergoing reoperations for primary hyperparathyroidism. (1988) (12)
The use of specific antibodies to identify and quantify guanine nucleotide-binding proteins. (1987) (12)
Characterization of the Promoter of the Human Gi2 α-Subunit Gene (1990) (12)
NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health (2006) (12)
Restoration of guanine nucleotide- and fluoride-stimulated activity to an adenylate cyclase-deficient cell line with affinity-purified guanine nucleotide regulatory protein. (1980) (11)
Guanine nucleotide binding proteins and signal transduction. (1988) (11)
Endogenous substrates for cAMP-dependent phosphorylation in dispersed bovine parathyroid cells. (1982) (11)
The use of high-resolution ultrasound to locate parathyroid tumors during reoperations for primary hyperparathyroidism (1987) (11)
Parathyroid imaging after intraarterial injections of [75Se]selenomethionine. (1981) (10)
Inherited endocrine diseases involving G proteins and G protein-coupled receptors. (2007) (10)
Focus on hereditary endocrine neoplasia. (2004) (9)
Hypocalcemic stimulation and nonselective venous sampling for localizing parathyroid adenomas: work in progress. (1998) (9)
The role of guanine nucleotides in regulation of adenylate cyclase activity. (1981) (9)
Embolization of a mediastinal parathyroid adenoma. (1974) (9)
CHAPTER 5 – Mechanism of Action of Hormones That Act at the Cell Surface (2011) (9)
Failure of ablation of a mediastinal parathyroid adenoma by repeated contrast staining. (1981) (8)
Inhibition of adenylate cyclase by arsenite and cadmium: evidence for a vicinal dithiol requirement. (1976) (8)
Detection of mediastinal parathyroid glands by nonselective digital arteriography. (1984) (8)
Preoperative localization of abnormal parathyroid: neck massage versus arteriography and selective venous sampling. (1978) (8)
Decreased insulin content and secretion in RIN 1046-38 cells overexpressing α2-Adrenergic receptorsreceptors (1997) (7)
Erratum: Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi in diabetes (Nature (1987) 327, (229-232) (1987) (7)
Cholera-toxin-dependent ADP-ribosylation of the adenylate cyclase regulatory protein in turkey erythrocyte membranes. (1981) (7)
Ultrasonic parathyroid localisation in previously operated patients. (1984) (7)
Cell signaling. beta-arrestin--not just for G protein-coupled receptors. (2003) (7)
Identification of multiple Gi subtypes and a novel G protein in bovine kidney cortex. (1989) (7)
Decreased insulin content and secretion in RIN 1046-38 cells overexpressing alpha 2-adrenergic receptors. (1997) (7)
Holocatalytic state of adenylate cyclase in turkey erythrocyte membranes: formation with guanylylimidodiphosphate plus isoproterenol without effect on affinity of beta-receptor. (1976) (6)
Management of primary parathyroid hyperplasia. (1976) (6)
BRIEF REPORT The Parathyroid/Pituitary Variant of Multiple Endocrine Neoplasia Type 1 Usually Has Causes Other than p27 Kip1 Mutations (2007) (6)
Direct Identification and Characterization of β-Adrenergic Receptors and Functional Relationship of Adenylyl Cyclase (1978) (6)
Baculovirus Expression and Purification of a Soluble, Mutant G-Protein α Subunit (1993) (6)
Gi 2 mediates a 2-adrenergic inhibition of adenylyl cyclase in platelet membranes : In situ identification with Ga C-terminal antibodies ( signal transduction / guanine nucleotide-binding proteins / receptors ) (6)
Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi in diabetes (1987) (5)
The stem cell wars: a dispatch from the front. (2013) (5)
Discussion section I (1991) (5)
G protein gene knockout hits the gut (1995) (5)
Receptor-effector coupling by G-proteins: implications for neuronal plasticity. (1990) (5)
Detection of multiple forms of Gi alpha in HL60 cells. (1987) (5)
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase. (1985) (5)
Urinary cyclic 3',5'-adenosine monophosphate (cAMP): an index of the action of parathyroid hormone on the kidney. (1980) (5)
Baculovirus expression and purification of a soluble, mutant G-protein alpha subunit. (1993) (4)
Chapter 24. G-proteins as Receptor-Effector Couplers (1988) (4)
ROLE OF G PROTEINS IN SIGNAL TRANSDUCTION (1992) (4)
Parathyroid aspiration directed by angiography: an alternative to venous sampling. (1984) (4)
Parathyroid gland morphology in nonparathyroid hormone-mediated hypercalcemia (1985) (4)
Antibodies as Probes of G-Protein Structure and Function (1990) (4)
Future diagnostic and therapeutic trends in endocrine cancers. (2010) (4)
G proteins: from basic to clinical studies. (1993) (4)
Inhibition of DNA Synthesis in Living Cells by Microinjection of (1992) (4)
News From the NIH (2000) (4)
The β subunit of the guanine nucleotide regulatory proteins: Identification of its location on two‐dimesional gels of brain tissue and its regional and subcellular distribution in brain (1986) (4)
Immunochemical studies of the 36-kDa common beta subunit of guanine nucleotide-binding proteins: identification of a major epitope. (1988) (4)
Scleral calcifications in hyperparathyroidism: demonstration by computed tomography. (1977) (4)
Scleral Calcifications in Hyperparathyroidism: Demonstration by Computed Tomography (1977) (4)
Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors (2011) (3)
Commentary: new guidelines for NIH peer review: improving the system or undermining it? (2010) (3)
Persistent hyperparathyroidism caused by incomplete parathyroid resection and a hyperfunctioning parathyroid autograft. (1983) (3)
12 Parathyroid hormone and vitamin D receptors (1983) (3)
Mitogenic effects of pertussis toxin-sensitive G-protein alpha subunits: the mitogenic action of alpha i2 in NIH 3T3 cells is mimicked by alpha i1, but not alpha i3. (1993) (3)
Gsα, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune–Albright Syndrome (2013) (3)
Guanine Nucleotide‐Binding Stimulatory Protein (1987) (3)
Characterization of the promoter of the human Gi2 alpha-subunit gene. (1990) (3)
Biochemical and immunochemical localization of GTP-binding proteins in the rat ileal enterocyte. (1993) (3)
Pheromone action regulates G-protein a-subunit myristoylation in the yeast Saccharomyces cerevisiae ( posttranslational modiflcation / mutants / adaptation ) (2005) (2)
The membrane localization of the G protein alpha s subunit is not dependent on its TENIR sequence or effector domain. (1994) (2)
Pseudohypoparathyroidism: deficiency of hormone receptor-adenylate cyclase coupling protein as a cause of hereditary hormone resistance. (1982) (2)
THE JEREMIAH METZGER LECTURE: A BRIEF HISTORY OF EUGENICS IN AMERICA: IMPLICATIONS FOR MEDICINE IN THE 21ST CENTURY. (2019) (2)
Human Ca2+ Receptor Extracellular Domain (2001) (2)
Increased adrenergic receptor content in membranes of stress induced erythrocytes (1975) (2)
Multiple Endocrine Neoplasia Type 1 : Clinical and Genetic Topics Moderator : (2009) (1)
THE USE OF SPECIFIC ANTISERA TO STUDY THE DEVELOPMENTAL REGULATION OF GUANINE NUCLEOTIDE BINDING PROTEINS (1987) (1)
Immunological Probes of the Structure, Function, and Expression of Heterotrimeric GTP-Binding Proteins (1992) (1)
G proteins--the disease spectrum expands. (2013) (1)
Gα s -Activating Mutations (1998) (1)
The GTP‐binding regulatory proteins of neuroblastoma × glioma, NG108‐15, and glioma, C6, cells (2001) (1)
Expression and functional characterization of five v2 vasopressin receptor gene mutations identified in families with x-linked nephrogenic diabetes insipidus (1996) (1)
Purification of parathyroid hormone like bioactivity from the rice leydig tumor of fisher rats (1984) (1)
Sulfonylureas Amplify Cyclic 3′, 5′ AMP Mediated Hormone Action (1970) (1)
Guanine Nucleotide Regulatory Proteins in Inflammatory and Immune Responses (1988) (1)
THE MCCUNE ALBRIGHT SYNDROME: A GENETICALLY DETERMINED SIGNAL TRANSDUCTION DISORDER (1993) (1)
Antiserum raised against residues 159-168 of the guanine nucleotide-binding protein GM 3-a reacts with ependymal cells and some neurons in the rat brain containing cholecystokinin-or cholecystokinin-and tyrosine 3-hydroxylase-like immunoreactivities ( transduction / glial cells / dopamine / neuropep (1)
High level expression of transfected G protein alpha i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts. (1992) (1)
Membrane attachment of recombinant G-protein alpha-subunits in excess of beta gamma subunits in a eukaryotic expression system. (1989) (1)
3 Gas-Activating Mutations A Cause of Acromegaly, Thyroid Adenomas, Fibrous Dysplasia, and the McCune-Albright Syndrome (1998) (1)
The G Protein Coupled to the Thromboxane Az Receptor in Human Platelets Is a Member of the Novel G , Family* (2001) (1)
Stable changes in expression or activation of G protein alpha i or alpha q subunits affect the expression of both beta 1 and beta 2 subunits. (1993) (1)
G‐protein‐mediated Signal Transduction and Human Disorders (2006) (1)
Citation for the 1999 Monsanto Clinical Investigator Lecture Award of the Endocrine Society to Dr. Stephen J. Marx. (1999) (0)
The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. (1991) (0)
Chymotrypsin selectively impairs forskolin stimulation of adenylate cyclase (1985) (0)
A double negative: inhibition of hepatic Gi signaling improves glucose homeostasis. (2018) (0)
Technetium-99m-SestamibiImaging before Reoperation for PrimaryHyperparathyroidism (1995) (0)
Susceptibility of the beta subunit of guanine nucleotide binding coupling proteins (G) to proteolytic cleavage (1985) (0)
Guanosine 5', alpha-beta-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: evidence against pyrophosphorylation mechanism. (1977) (0)
Incidence of primary hyperparathyroidism. (1980) (0)
Partnering and functioning of the MEN1 tumour suppressor gene (2004) (0)
Contents (2020) (0)
The calcilytic agent NPS2143 rectifies hypocalcaemia in a mouse model, Nuf, that is due to an activating calcium-sensing-receptor (CaSR) mutation: relevance to autosomal dominant hypocalcaemia with hypercalciuria (2008) (0)
Erratum to J Intern Med 2004; 255: 692–730 (2004) (0)
Diagnosis of Radiosensitive Hypothalamic Tumors Without Craniotomy (2020) (0)
In memoriam Gerald D. Aurbach. (1992) (0)
Methods in enzymology: Vol. 195, adenylyl cyclase, G proteins, and guanylyl cyclase. Edited by Roger A. Johnson and Jackie D. Corbin. Academic Press, San Diego, CA, 511 pp. $69.00 (1991) (0)
Citation for the 1997 Gerald D. Aurbach Lecture Award of The Endocrine Society to Edward M. Brown. (1997) (0)
G Protein-Regulated Signaling Dysfunction in Human Disease: A Personal Historical Perspective (2003) (0)
GTPanalogues promote release ofthea subunit oftheguanine nucleotide binding protein, Gj2, frommembranes ofratglioma C6BUlcells (1988) (0)
Parathyroid tumors in familial multiple endocrine neoplasia type 1: The role of direct acting oncogenes and tumor suppressor genes (1990) (0)
The calcilytic NPS2143 rectifies the gain-of-function associated with G-protein [alpha] 11 mutations causing autosomal dominant hypocalcaemia type 2 (2014) (0)
In memoriam Gerald D. Aurbach. (1992) (0)
Albert Einstein College of Medicine. (2008) (0)
Erratum: Identification of multiple G(i) subtypes and a novel G protein in bovine kidney cortex (Biochemical Pharmacology, Vol. 38 (1989) 4502-4505) (1990) (0)
Mutational analysis of the carboxyl-terminal region of the human calcium-sensing receptor (1997) (0)
Methods in Enzymology, Volume 237, Heterotrimeric G Proteins, edited by Ravi Iyengar, Academic Press, San Diego, 1994, 519 pp., $89.00. (1994) (0)
Exaggerated cyclic AMP response to parathyroid hormone in familial hypocalciuric hypercalcemia (1979) (0)
Parathyroid hormone and vitamin D receptors. (1983) (0)
Results of Reoperation for No. 6 Persistent and Recurrent Hyperpara thyroidism (1981) (0)
Gerald D. Aurbach, 1927-1991 (1993) (0)
Following in the Footsteps of a “Neuroscience” Giant (2016) (0)
Expression and function of the calcium sensing receptor (CaR) in gastrinomas (2000) (0)
Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas (2006) (0)
List of Contributors and Discussants (1981) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Allen M. Spiegel?

Allen M. Spiegel is affiliated with the following schools:

Allen M. Spiegel's Academic­Influence.com Rankings

Why Is Allen M. Spiegel Influential?

Allen M. Spiegel's Published Works

Published Works

What Schools Are Affiliated With Allen M. Spiegel?

Allen M. Spiegel's AcademicInfluence.com Rankings