Albert Sjoerdsma
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Chemistry Biology
Albert Sjoerdsma's Degrees
- PhD Biochemistry University of Amsterdam
- Masters Chemistry University of Amsterdam
- Bachelors Chemistry University of Amsterdam
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(Suggest an Edit or Addition)Albert Sjoerdsma's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART. (1965) (985)
- BLOCKADE OF ENDOGENOUS NOREPINEPHRINE SYNTHESIS BY ALPHA-METHYL-TYROSINE, AN INHIBITOR OF TYROSINE HYDROXYLASE. (1965) (851)
- Tryptophan Hydroxylation: Measurement in Pineal Gland, Brainstem, and Carcinoid Tumor (1967) (452)
- Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin. (1967) (414)
- Polyamine metabolism: a potential therapeutic target in trypanosomes. (1980) (369)
- Increased synthesis of norepinephrine and epinephrine in the intact rat during exercise and exposure to cold. (1966) (341)
- Altered urinary kallikrein excretion in human hypertension. (1971) (314)
- Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo. (1968) (291)
- RELEASE OF A KININ PEPTIDE IN THE CARCINOID SYNDROME. (1964) (269)
- L-Ornithine decarboxylase:an essential role in early mammalian embryogenesis. (1980) (229)
- A clinical, physiologic and biochemical study of patients with malignant carcinoid (argentaffinoma). (1956) (229)
- Reversal of chloroquine resistance in malaria parasite Plasmodium falciparum by desipramine. (1988) (228)
- Inhibition of polyamine metabolism : biological significance and basis for new therapies (1987) (226)
- Chemotherapeutic implications of polyamine biosynthesis inhibition (1984) (226)
- Decarboxylase Inhibition and Blood Pressure Reduction by α-Methyl-3,4-Dihydroxy-DL-phenylalanine (1960) (225)
- Monoamine Oxidase Inhibitors, Tyramine, and Cheese (1964) (225)
- Physiologically active amines in common fruits and vegetables. (1959) (215)
- Serotonin, norepinephrine, and related compounds in bananas. (1958) (215)
- THE EFFECT OF 4‐AMINO HEX‐5‐YNOIC ACID (γ‐ACETYLENIC GABA, γ‐ETHYNYL GABA) A CATALYTIC INHIBITOR OF GABA TRANSAMINASE, ON BRAIN GABA METABOLISM IN VIVO (1977) (213)
- Formation of indole-3-acetic acid and tryptamine in animals: a method for estimation of indole-3-acetic acid in tissues. (1959) (212)
- Further studies on tryptophan hydroxylase in rat brainstem and beef pineal. (1969) (211)
- THE CARDIAC DISEASE ASSOCIATED WITH THE CARCINOID SYNDROME (CARCINOID HEART DISEASE). (1964) (189)
- Tryptophan hydroxylation in mammalian systems. (1968) (184)
- TURNOVER AND METABOLISM OF CATECHOLAMINES IN PATIENTS WITH PHEOCHROMOCYTOMA. (1964) (181)
- Inhibition of serotonin synthesis by para-chlorophenylalanine in patients with the carcinoid syndrome. (1967) (171)
- V. CATECHOLAMINES CYCLIC AMP‐ANGIOTENSIN RECEPTORS: Plasma Catecholamine Concentrations in Patients with Hypertension (1970) (171)
- Urinary excretion of catecholamines and their metabolites in pheochromocytoma. (1961) (167)
- A unique syndrome associated with secretion of 5-hydroxytryptophan by metastatic gastric carcinoids. (1962) (166)
- End-product inhibition of tyrosine hydroxylase as a possible mechanism for regulation of norepinephrine synthesis. (1967) (163)
- Altered Urinary Kallikrein Excretion in Rats with Hypertension (1972) (159)
- Significance of urinary hydroxyproline in man. (1961) (159)
- Biochemical and clinical effects of γ‐vinyl GABA in patients with epilepsy (1984) (153)
- Norepinephrine Metabolism in Brainstem of Spontaneously Hypertensive Rats (1970) (151)
- Biochemical and pharmacologic effects of α-methyltyrosine in man (1968) (151)
- Treatment of gambiense sleeping sickness in the Sudan with oral DFMO (DL-alpha-difluoromethylornithine), an inhibitor of ornithine decarboxylase; first field trial. (1985) (149)
- Pheochromocytoma: current concepts of diagnosis and treatment. Combined clinical staff conference at the National Institutes of Health. (1966) (149)
- Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis. (1984) (148)
- Effects of L-tryptophan (a natural sedative) on human sleep. (1970) (143)
- INHIBITION OF HISTAMINE SYNTHESIS IN THE RAT BY ALPHA-HYDRAZINO ANALOG OF HISTIDINE AND 4-BROMO-3-HYDROXY BENZYLOXYAMINE. (1965) (138)
- Effect of penicillamine on human collagen and its possible application to treatment of scleroderma. (1966) (136)
- Clinical and Chemical Studies with &agr;‐Methyl‐Dopa in Patients with Hypertension (1962) (128)
- Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis; effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. (1980) (127)
- Serotonin and histamine in mast cells. (1957) (126)
- Identification and assay of urinary tryptamine: application as an index of monoamine oxidase inhibition in man. (1959) (121)
- Increased gamma-aminobutyric acid (GABA), homocarnosine and β-alanine in cerebrospinal fluid of patients treated with γ-vinyl GABA (4-amino-hex-5-enoic acid) (1981) (120)
- Elevated histaminase activity in medullary carcinoma of the thyroid gland. (1970) (119)
- In vivo effects of α-dl-Difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei (1983) (118)
- Collagen profile in various clinical conditions. (1966) (115)
- Antifibrinolytic activity and metabolism of 6-aminocaproic acid in man. (1960) (114)
- Suicide enzyme inhibitors as potential drugs (1981) (114)
- Inhibition of catecholamine synthesis in man with alpha-methyl-tyrosine, an inhibitor of tyrosine hydroxylase. (1965) (113)
- Collagen synthesis in human keloid and hypertrophic scar. (1972) (113)
- Gastrointestinal absorption and renal excretion of hydroxyproline peptides. (1962) (112)
- Studies on the Metabolism and Mechanism of Action of Methyldopa (1963) (111)
- CLINICAL, PHYSIOLOGICAL AND BIOCHEMICAL STUDIES OF A PATIENT WITH XANTHINURIA AND PHEOCHROMOCYTOMA. (1964) (107)
- SIMPLE TEST FOR DIAGNOSIS OF METASTATIC CARCINOID (ARGENTAFFINOMA) (1955) (106)
- Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing. (1987) (106)
- Serotonin now: clinical implications of inhibiting its synthesis with para-chlorophenylalanine. (1970) (106)
- A HYDROXYPROLINE-CONTAINING, COLLAGEN-LIKE PROTEIN IN PLASMA AND A PROCEDURE FOR ITS ASSAY. (1964) (105)
- Studies on histamine in human urine using a fluorometric method of assay. (1962) (100)
- Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase (1990) (96)
- 16 – Clinical Aspects of Inhibition of Ornithine Decarboxylase with Emphasis on Therapeutic Trials of Eflornithine (DFMO) in Cancer and Protozoan Diseases (1987) (95)
- Further observations on patients with malignant carcinoid. (1957) (94)
- Distinctive clinical and therapeutic aspects of the syndrome associated with bronchial carcinoid tumors. (1965) (92)
- Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria. (1989) (91)
- A NEW TEST FOR PHEOCHROMOCYTOMA. PRESSOR RESPONSIVENESS TO TYRAMINE. (1964) (90)
- Tumor suppression with a combination of alpha-difluoromethyl ornithine and interferon. (1983) (89)
- Studies on the metabolism of aromatic amines in relation to altered thyroid function in man. (1962) (89)
- Effects of dibutyryl-3',5'-cyclic adenosine monophosphage, phosphodiesterase inhibitors and prostaglandin E1 on compound 48-80-induced histamine release from rat peritoneal mast cells in vitro. (1971) (89)
- Increased excretion of hydroxyproline in Marfan's syndrome. (1958) (88)
- Pressor amines and the carcinoid flush. (1963) (87)
- Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer. (1986) (86)
- Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor. (1981) (85)
- Increased synthesis of norepinephrine in the rat heart on electrical stimulation of the stellate ganglia. (1966) (84)
- Urinary excretion of the serotonin metabolite, 5-hydroxyindoleacetic acid, in various clinical conditions. (1956) (78)
- Metabolism of alpha-methyltyrosine in man: relationship to its potency as an inhibitor of catecholamine biosynthesis. (1968) (77)
- Effects of DL-alpha-difluoromethylornithine on Leishmania donovani promastigotes. (1986) (76)
- Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis. (1985) (76)
- The clinical and laboratory significance of serotonin and catechol amines in bananas. (1959) (75)
- Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitor (1992) (73)
- Effects of several monoamine oxidase inhibitors on the cardiovascular actions of naturally occurring amines in the dog. (1959) (71)
- Reactivity to norepinephrine and nature of the alpha adrenergic receptor in vascular smooth muscle of a genetically hypertensive rat. (1970) (69)
- Synthesis and Turnover of Norepinephrine in the Heart of the Spontaneously Hypertensive Rat (1969) (69)
- Effects of 5-hydroxytryptophan on the sleep of normal human subjects. (1971) (69)
- Antiseizure activity of gamma-acetylenic gamma-aminobutyric acid: a catalytic irreversible inhibitor of gamma-aminobutyric acid transaminase. (1977) (68)
- Urinary Kallikrein Excretion in Hypertension (1972) (67)
- Serotonin Synthesis in Carcinoid Patients (1960) (67)
- Effect of Catecholamines and Adrenergic Blocking Agents on Oxidative Phosphorylation in Rat Heart Mitochondria (1966) (66)
- CHRONIC MEDICAL THERAPY FOR PHEOCHROMOCYTOMA; A REPORT OF FOUR CASES. (1964) (66)
- Pneumocystis carinii pneumonia treated with alpha-difluoromethylornithine. A prospective study among patients with the acquired immunodeficiency syndrome. (1984) (64)
- Hydroxyproline and Collagen Metabolism: Clinical Implications: Combined Clinical Staff Conference at the National Institutes of Health (1965) (64)
- Restriction of bacterial growth by inhibition of polyamine biosynthesis by using monofluoromethylornithine, difluoromethylarginine and dicyclohexylammonium sulphate. (1982) (64)
- Studies with the serotonin precursor, 5-hydroxytryptophan, in experimental animals and man. (1957) (64)
- Effects of para-chlorophenylalanine on sleep in man. (1969) (64)
- ANTI-HIV ACTIVITY OF CASTANOSPERMINE ANALOGUES (1989) (64)
- Norepinephrine Synthesis from Tyrosine-C14 in Isolated Perfused Guinea Pig Heart (1963) (62)
- Proline-hydroxylase activity in human blood. (1970) (62)
- Increased protocollagen proline hydroxylase activity in sclerodermatous skin. (1971) (61)
- Biochemical and clinical effects of gamma-vinyl GABA in patients with epilepsy. (1984) (60)
- Catecholamine turnover in normotensive and hypertensive man: effects of antiadrenergic drugs. (1968) (60)
- THE CARCINOID SPECTRUM. (1964) (60)
- New drug combination for experimental late-stage African trypanosomiasis: DL-alpha-difluoromethylornithine (DFMO) with suramin. (1984) (59)
- Necessity of antibody response in the treatment of African trypanosomiasis with alpha-difluoromethylornithine. (1986) (59)
- RELATION BETWEEN URINARY HYDROXYPROLINE AND PARATHYROID FUNCTION. (1964) (59)
- Plasmodium falciparum and Plasmodium berghei: effects of ornithine decarboxylase inhibitors on erythrocytic schizogony. (1987) (59)
- Effect of tissue norepinephrine depletion by 6-hydroxydopamine on blood pressure in spontaneously hypertensive rats. (1972) (59)
- Increased synthesis of catecholamines in the intact rat following administration of alpha-adrenergic blocking agents. (1968) (58)
- Studies on the biogenesis and metabolism of norepinephrine in patients with pheochromocytoma. (1959) (58)
- Increased blood pressure responses to dopamine and norepinephrine produced by monoamine oxidase inhibitors in man. (1960) (58)
- History of Serotonin and Serotonin Disorders (1990) (57)
- Relationships Between Alterations in Amine Metabolism and Blood Pressure (1961) (56)
- TREATMENT OF MALABSORPTION AND DIARRHEA OF THE CARCINOID SYNDROME WITH METHYSERGIDE. (1965) (56)
- Improvements in methods for measuring hydroxyproline: application to human urine. (1959) (55)
- Studies on beta‐aminopropionitrile in patients with scleroderma (1967) (54)
- Alterations in the Pattern of Amine Excretion in Man Produced by a Monoamine Oxidase Inhibitor (1959) (54)
- A sensitive assay of monoamine oxidase activity in vitro: application to heart and sympathetic ganglia. (1962) (52)
- Conversion of Phenylalanine to Phenethylamine in Patients with Phenylketonuria (1963) (52)
- Effects of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor or ornithine decarboxylase, on testosterone-induced regeneration of prostate and seminal vesicle in castrated rats. (1979) (52)
- Studies on the spontaneously hypertensive rat. Genealogy, effects of varying salt intake, and kinetics of catecholamine metabolism. (1969) (51)
- CLINICAL SIGNIFICANCE OF A HYDROXYPROLINE-CONTAINING PROTEIN IN HUMAN PLASMA. (1965) (51)
- Loss of taste during therapy with penicillamine. (1968) (50)
- Treatment of human late stage gambiense trypanosomiasis with alpha-difluoromethylornithine (eflornithine): efficacy and tolerance in 14 cases in Côte d'Ivoire. (1987) (49)
- Brain Catecholamines and Human Sleep (1971) (49)
- Effects of l‐dopa and inhibitors of decarboxylase and monoamine oxidase on brain noradrenaline levels and blood pressure in spontaneously hypertensive rats (1972) (48)
- The fate of papaverine in man and other mammals. (1958) (48)
- A SIMPLE METHOD FOR THE MEASUREMENT OF MONOAMINE-OXIDASE INHIBITION IN MAN (1958) (47)
- Enzyme Defect in a Case of Xanthinuria (1964) (46)
- Further studies on difluoromethylornithine in African trypanosomes. (1981) (46)
- Impairment of macrophage function by inhibitors of ornithine decarboxylase activity (1987) (46)
- Difluoromethylornithine, an effective new treatment of Gambian trypanosomiasis. Results in five patients. (1987) (45)
- The presence and distribution of tyramine in mammalian tissues. (1963) (45)
- Distribution of Serum Zinc Between Albumin and α2‐Macroglobulin in Patients with Decompensated Hepatic Cirrhosis (1976) (44)
- Inhibition of testosterone 5 alpha-reductase by a proposed enzyme-activated, active site-directed inhibitor. (1980) (44)
- A METHOD FOR MEASUREMENT OF MONOAMINE OXIDASE INHIBITION IN MAN: APPLICATION TO STUDIES ON HYPERTENSION (1959) (43)
- THE EFFECTS OF RESERPINE AND CHLORPROMAZINE ON GASTRIC SECRETION (1955) (43)
- Effects of the ornithine decarboxylase inhibitors DL-alpha-difluoromethylornithine and alpha-monofluoromethyldehydroornithine methyl ester alone and in combination with suramin against Trypanosoma brucei brucei central nervous system models. (1987) (42)
- Uptake of α-difluoromethylornithine by Trypanosoma brucei brucei (1986) (42)
- Collagen-Like Protein in Human Plasma (1963) (42)
- Identification of p-hydroxy-alpha-(methylaminomethyl) benzyl alcohol (synephrine) in human urine. (1961) (41)
- Characterization of a tryptophan hydroxylating enzyme from malignant mouse mast cell. (1967) (40)
- Characteristics of carcinoid tumor kallikrein: Identification of lysyl-bradykinin as a peptide it produces in vitro (1965) (40)
- Difiuoromethylornithine in the treatment of African trypanosomiasis. (1986) (40)
- Arginine decarboxylase inhibitors reduce the capacity of Trypanosoma cruzi to infect and multiply in mammalian host cells. (1987) (40)
- Antimalarial polyamine analogues. (1991) (39)
- Suppression of both antimony-susceptible and antimony-resistant Leishmania donovani by a bis(benzyl)polyamine analog (1990) (39)
- Antagonism by polyamines of the curative effects of alpha-difluoromethylornithine in Trypanosoma brucei brucei infections. (1981) (38)
- Reduced binding of added zinc in serum of patients with decompensated hepatic cirrhosis (1977) (38)
- Reduction of the central effects of tryptophan by a decarboxylase inhibitor (1964) (38)
- Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis. (1983) (37)
- Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides (1994) (37)
- alpha-Difluoromethylornithine: a promising lead for preventive chemotherapy for coccidiosis. (1982) (34)
- Inheritance of high blood-pressure in the spontaneously hypertnsive rat. (1969) (34)
- Plasmodium berghei: inhibitors of ornithine decarboxylase block exoerythrocytic schizogony. (1985) (34)
- A tryptophan hydroxylase in cell-free extracts of malignant mouse mast cells. (1965) (33)
- Lactation Due to Methyldopa (1963) (33)
- Successful treatment of lethal protozoal infections with the ornithine decarboxylase inhibitor, alpha-difluoromethylornithine. (1984) (33)
- In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei. (1983) (32)
- Changes in plasma histaminase activity during normal early human pregnancy and pregnancy disorders. (1975) (32)
- HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE IN NEOPLASTIC MAST CELLS OF THE MOUSE. (1964) (32)
- The application of a monoamine-oxidase inhibitor, I-phenyl-2-hydrazinopropane (JB-516), to the treatment of primary hypertension. (1959) (32)
- Direct measurement of the rate of collagen synthesis in skin. (1969) (31)
- The mechanism of inhibition of horse liver alcohol dehydrogenase by thyroxine and related compounds. (1968) (30)
- Polyamine biosynthesis is required for the maintenance of peripheral blood cell elements in the rat. (1983) (30)
- Origin of urinary tyramine and tryptamine. (1967) (30)
- The Fixation of Radioactive Digitoxin by Isolated Hearts (1951) (30)
- Aliphatic Amino Compounds as Inhibitors of Plasminogen Activation (1960) (29)
- The Tissue Distribution and Excretion of Radioactive Digitoxin: Studies on Normal Rats and Cats, and Rats with Dietary‐Induced Myocardial Lesions (1952) (29)
- Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid). (1981) (29)
- Inhibition of polyamine metabolism (1988) (29)
- Design and early clinical evaluation of selective inhibitors of monoamine oxidase (1988) (29)
- α‐DIFLUOROMETHYL DOPA, A NEW ENZYME‐ACTIVATED IRREVERSIBLE INHIBITOR OF AROMATIC L‐AMINO ACID DECARBOXYLASE (1978) (28)
- Biochemical and pharmacologic effects of alpha-methyltyrosine in man. (1968) (28)
- Marked and prolonged inhibition of mammalian ornithine decarboxylase in vivo by esters of (E)-2-(fluoromethyl)dehydroornithine. (1986) (28)
- Enhancement by Methyldopa of Tyramine Sensitivity in Man (1963) (28)
- Inhibition of polyamine biosynthesis by alpha-difluoromethylornithine in African trypanosomes and Pneumocystis carinii as a basis of chemotherapy: biochemical and clinical aspects. (1986) (27)
- AN ORAL TYROSINE TOLERANCE TEST IN THYROTOXICOSIS AND MYXEDEMA. (1965) (27)
- NEWER BIOCHEMICAL APPROACHES TO THE TREATMENT OF HYPERTENSION (1960) (27)
- URINARY EXCRETION OF PHENOLIC ACIDS IN HUMAN SUBJECTS ON A GLUCOSE DIET. (1964) (26)
- Interactions of tricyclic antidepressants and 5-hydroxyindolealkylamine precursors on spinal monosynaptic reflex transmission. (1971) (26)
- ESTIMATION OF MONOAMINE OXIDASE ACTIVITY IN MAN: TECHNIQUES AND APPLICATIONS (1963) (26)
- Inhibition of Glycoprotein Processing and HIV Replication by Castanospermine Analogues (1990) (26)
- Action and metabolism of chlorpromazine sulfoxide in man. (1957) (26)
- DISSOCIATION OF THE DECARBOXYLASE-INHIBITING AND NOREPINEPHRINE-DEPLETING EFFECTS OF α-METHYL-DOPA, α-ETHYL-DOPA, 4-BROMO-3-HYDROXY-BENZYLOXYAMINE AND RELATED SUBSTANCES (1964) (25)
- Inhibition of growth of Mycoplasma dispar by DL-alpha-difluoromethyllsine, a selective irreversible inhibitor of lysine decarboxylase, and reversal by cadaverine (1,5-diaminopentane). (1984) (24)
- Demonstration of the 3-methoxy analog of norepinephrine in man. (1958) (24)
- FURTHER STUDIES OF PLASMA TYROSINE IN PATIENTS WITH ALTERED THYROID FUNCTION. (1964) (24)
- Renin-like activity in submaxillary gland in several strains of rats including the spontaneously hypertensive rat. (1972) (23)
- Effect of parathyroid extract on collagen metabolism. (1966) (23)
- Cytotoxicity of methylglyoxal bis(guanylhydrazone) in combination with alpha-difluoromethylornithine against HeLa cells and mouse L1210 leukemia. (1983) (23)
- Novel combination chemotherapy of experimental trypanosomiasis by using bleomycin and DL-alpha-difluoromethylornithine; reversal by polyamines. (1982) (23)
- Long-term maintenance therapy of established human small cell variant lung carcinoma implants in athymic mice with a cyclic regimen of difluoromethylornithine. (1986) (22)
- Eflornithine for African sleeping sickness (1999) (21)
- Dissociation of morphine tolerance and dependence from brain serotonin synthesis rate in mice. (1972) (21)
- Biochemical and pharmacological effects of iodo-tyrosines; relation to tyrosine hydroxylase inhibition in vivo. (1965) (21)
- ELEVATED PLASMA FREE FATTY ACID CONCENTRATIONS IN PATIENTS WITH PHEOCHROMOCYTOMA. CHANGES WITH THERAPY AND CORRELATIONS WITH THE BASAL METABOLIC RATE. (1964) (21)
- FURTHER STUDIES ON THE INHIBITION OF MONOAMINE SYNTHESIS BY MONOFLUOROMETHYLDOPA (1980) (20)
- Clinical and laboratory features of malignant carcinoid. (1958) (20)
- Antitumor activity of norspermidine, a structural homologue of the natural polyamine spermidine. (1988) (20)
- Identification of polyamines in the cochlea of the rat and their potential role in hearing (1986) (20)
- Inhibition of Catecholamine Biosynthesis in Man (1966) (20)
- Further evaluation of the tyramine test for pheochromocytoma. (1968) (20)
- Noradrenaline in the heart of the spontaneously hypertensive rat. (1968) (20)
- Decarboxylase inhibition and blood pressure reduction by alpha-methyl-3,4-dihydroxy-DL-phenylalanine. (1960) (20)
- URINARY EXCRETION OF PHENETHYLAMINE AND TYRAMINE IN NORMAL SUBJECTS AND HETEROZYGOUS CARRIERS OF PHENYLKETONURIA. (1964) (19)
- Studies on tryptophan and serotonin in patients with malignant carcinoid. (1956) (18)
- A modified procedure for radioactive hydroxyproline assay in urine and tissues after labeled proline administration. (1966) (18)
- EFFECTS OF ALPHA-METHYL-META-TYROSINE INTRAVENOUSLY IN MAN. (1964) (18)
- DENERVATION HYPERSENSITIVITY OF ADIPOSE TISSUE IN IDIOPATHIC ORTHOSTATIC HYPOTENSION. (1964) (17)
- Catecholamine Metabolism in the Spontaneously Hypertensive Rat (1972) (17)
- SEROTONIN IN PLATELETS: ITS UPTAKE AND DISAPPEARANCE AFTER ADMINISTRATION OF THE AMINE BY MOUTH. (1963) (17)
- Contraction of left leaf of diaphragm coincident with cardiac systole. (1954) (17)
- Relative Lack of Pharmacologic Action of 3-Methoxy Analogue of Norepinephrine.∗ (1958) (17)
- DOPAMINE‐β‐OXIDASE ACTIVITY IN MAN, USING HYDROXYAMPHETAMINE AS SUBSTRATE (1963) (16)
- 542 Pharmacology and biochemistry of α-methyl-dopa in man and experimental animals (1961) (16)
- Elevated plasma levels of a hydroxyproline-containing protein in Hodgkin's disease and their relation to disease activity. (1966) (16)
- The effect of 4-amino hex-5-ynoic acid (gamma-acetylenic GABA, gammma-ethynyl GABA) a catalytic inhibitor of GABA transaminase, on brain GABA metabolism in vivo. (1977) (15)
- SEVERE FLUSHING REACTIONS RESPONSIVE TO STEROIDS IN PATIENTS WITH BRONCHIAL CARCINOID. (1964) (15)
- Central action as a key to past and future therapy of hypertension. (1977) (15)
- Use of two enzyme inhibitors in hypertension therapy. (1963) (14)
- Determination of epsilon-Aminocaproic Acid in Urine by Means of High-Voltage Paper Electrophoresis. (1959) (14)
- Subcellular distribution and properties of rat brain stem tryptophan hydroxylase. (1968) (14)
- Hyperaminoacidemia in rabbits treated with 6-azauridine triacetate. (1971) (14)
- Quantitation of Monoamine Oxidase Inhibition Produced with Various Drugs in Man.∗ (1960) (14)
- Participation of T-lymphocytes in the curative effect of a novel synthetic polyamine analogue, N,N'-bis[3-(ethylamino)propyl]-1,7-heptanediamine, against L1210 leukemia in vivo. (1991) (14)
- Catecholamine metabolism in patients with pheochromocytoma. (1959) (14)
- Studies on the role of catecholamines as regulators of tyrosine aminotransferase. (1969) (13)
- E. CATECHOLAMINE-DRUG INTERACTIONS IN MAN (1966) (13)
- Introduction: Polyamine Metabolism (1987) (13)
- 14 – THERAPEUTIC UTILITY OF SELECTED ENZYME-ACTIVATED IRREVERSIBLE INHIBITORS (1989) (12)
- African sleeping sickness in the United States. Successful treatment with eflornithine. (1988) (12)
- Antitumor activity of a novel synthetic polyamine analogue, N,N'-bis-[3-(ethylamino)-propyl]-1-7-heptane diamine: potentiation by polyamine oxidase inhibitors. (1990) (12)
- Decarboxylated-S-adenosylmethionine excretion: a biochemical marker of ornithine decarboxylase inhibition by alpha-difluoromethylornithine. (1987) (12)
- Restoration of Tyramine Pressor Responses in Reserpine-Treated Animals by Methyldopa and Its Amine Metabolites (1965) (11)
- Antihypertensive and noradrenaline-depleting effects of α-methyl-5-hydroxytryptophan in the rat (1969) (11)
- Urinary homovanillic acid in phaeochromocytoma. (1965) (11)
- Attenuation of cardiovascular responses to exercise as a possible basis for effectiveness of monoamine oxidase inhibitors in angina pectoris. (1962) (11)
- MALIGNANT CARCINOID a new metabolic disorder (1957) (10)
- A comparison of amine oxidase activity in human skin, rat skin and rat liver: relevance to collagen cross-linking. (1968) (10)
- The cardiovascular manifestations of functioning carcinoid tumors. (1956) (10)
- Metabolism of 5-Hydroxy-D- and L-Tryptophan in Man (1961) (10)
- Potentiation by alpha-difluoromethylornithine of the activity of 3,4-dihydroxybenzylamine, a tyrosinase-dependent melanolytic agent, against B16 melanoma. (1985) (10)
- Clinical relevance of measuring GABA concentrations in cerebrospinal fluid (1990) (9)
- Lysergic acid diethylamide in patients with excess serotonin. (1956) (9)
- UNUSUAL EFFECT OF SOME α‐MERCAPTOACRYLIC ACIDS ON METABOLISM OF ZINC IN THE RAT (1977) (9)
- Monoamine oxidase and decarboxylase inhibitors as antihypertensive agents. (1961) (9)
- A multicenter, open study of the non-sedating antihistamine, terfenadine (Seldane), in the maintenance therapy of seasonal allergic rhinitis. (1988) (9)
- The effects of polyamine analogues on malaria parasites in vitro and in vivo. (1988) (8)
- Collagen synthesis in granulating wounds of rats and man. (1969) (7)
- Serotonin synthesis in carcinoid patients. Its inhibition by alpha-methyl-dopa, with measurement of associated increases in urinary 5-hydroxytryptophan. (1960) (7)
- Late-stage African trypanosomiasis and eflornithine. (1986) (7)
- Curative effect of alpha-difluoromethylornithine on fatal Trypanosoma congolense infection in mice. (1982) (7)
- Alpha-methyldopa: antihypertensive drug with unusual mechanism of action. (1963) (5)
- Catecholamines in hypertension. (1970) (5)
- MONOAMINE OXIDASE INHIBITORS, TYRAMINE, AND CHESSE. (1964) (5)
- Catecholamines and the Drug Therapy of Hypertension (1967) (4)
- Catechol amine excretion after banana feeding. (1959) (4)
- Scientific exhibits. (1957) (4)
- The antiarrhythmic action of ambonestyl (2-diethylaminoethylisonicotinamide, MC-4112). (1956) (4)
- Reduction of tissue norepinephrine and blood pressure by 3,5-dihydroxy-4-methoxy-phenylalanine. (1968) (4)
- Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei. (1986) (4)
- The Effects of Anesthetic Agents on Serum Proline Hydroxylase (1972) (3)
- Inhibition of ornithine or arginine decarboxylase as an experimental approach to African or American trypanosomiasis. (1988) (3)
- Antihypertensive and noradrenaline-depleting effects of alpha-methyl-5-hydroxytryptophan in the rat. (1969) (3)
- Serotonin, Norepinephrine, and Related Compounds in Bananas. (1958) (3)
- Editorial: Chemotherapy of Hypertension Yesterday—Today—Tomorrow (1963) (3)
- Hormone‐induced modifications of free tyrosine in the rat thyroid gland (1969) (3)
- Catecholamine-drug interactions in man. (1966) (3)
- DISSOCIATION OF THE DECARBOXYLASE-INHIBITING AND NOREPINEPHRINE-DEPLETING EFFECTS OF ALPHA-METHYL-DOPA, ALPHA-ETHYL-DOPA, 4-BROMO-3-HYDROXY-BENZYLOXYAMINE AND RELATED SUBSTANCES. (1964) (2)
- Polyamine biosynthesis as a target for the chemotherapy of trypanosomatid infections : AFRICAN TRYPANOSOMIASIS (1991) (2)
- The possible significance of a T-wave variant as determined from its age distribution and prevalence prior to myocardial infarction. (1955) (2)
- Clinical implications of unnatural amino acids and amines. (1971) (1)
- Drugs which alter the metabolism of vasoactive monoamines. (1959) (1)
- Methods for the study of the treatment of protozoan diseases by inhibitors of ornithine decarboxylase. (1983) (1)
- Attacks simulating pheochromocytoma in patients with angina pectoris. (2009) (1)
- Impairment ofMacrophage Function byInhibitors ofOrnithine Decarboxylase Activity (1987) (1)
- CENTRAL CATECHOLAMINES AND HYPERTENSION (1974) (1)
- CHEMOTHERAPY OF HYPERTENSION: YESTERDAY--TODAY--TOMORROW. (1963) (1)
- THE EFFECT OF METHANTHELINE BROMIDE (BANTHINE) ON PULMONARY VENTILATION IN BRONCHIAL ASTHMA AND PULMONARY EMPHYSEMA (1954) (1)
- Protocollagen Proline Hydroxylase Activity in Blood. (1971) (1)
- Hydroxyproline and Collagen Metabolism (2020) (1)
- Pharmacologic aspects of hypertension. (1955) (0)
- Chronic Medical Therapy for Pheochromocytoma (2020) (0)
- Decarboxylated-5-adenosylmethionine Excretion: A Biochemical Marker of Ornithine Decarboxylase Inhibition by a-Difluoromethylornithine (2006) (0)
- FIXATION OF RADIOACTIVE DIGITOXIN BY ISOLATEI 1 D HEIARTS (0)
- ENZYME-ACTIVATED IRREVERSIBLE INHIBITION OF AROMATIC L-AMINO ACID DECARBOXYLASE (AADC) BY α-DIFLUOROMETHYL DOPA (DFMD, RMI 71.801) AND α-MONOFLUOROMETHYL DOPA (MFMD, RMI 71.963) (1979) (0)
- The properties of a tryptophan hydroxylase from neoplastic mouse cells. Abstr. (1965) (0)
- Estimation of monamine oxidase activity in man: techniques and applications. (1963) (0)
- Pheochromocytoma: Current Concepts of Diagnosis and Treatment (2020) (0)
- A study of the pharmacological relationship between digitoxin and histamine. (1948) (0)
- Studies on Tryptophan and Serotonin in Patients with Malignant Carcinoid (1956) (0)
- Metabolism of C14 bradykinin in man (1969) (0)
- Bis(benzyl)polyamine analogs inhibit the growth of chloroquine- resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with a-difluoromethylornithine (2016) (0)
- Blood barrier to 5-HTP. (1968) (0)
- Tyrosine and tryptophan analogues as MAO-inhibiting prodrugs (1990) (0)
- Long-Term Maintenance Therapy of Established Human Small Cell Variant Lung Carcinoma Implants in Athymic Mice with a Cyclic Regimen of Difluoromethylornithine1 (2006) (0)
- CATECHOLAMINES AND PHEOCHROMOCYTOMA Table 1 Urinary Excretion of Free Catecholamines and Patients with Pheochromocytoma Location of the Tumor in Eighteen (2005) (0)
- Combination chemotherapy with dl-alpha-difluoromethylornithine (dfmc) and cytosine arabinoside (ara-c) in experimental murine tumors. Abstr. (1981) (0)
- Clinical aspects of indolealkylamine metabolism. Introductory remarks. (1968) (0)
- Pneumocystis carinil Pneumonia Treated With a-Difluoromethylorn ithi ne A Prospective Study Among Patients With the Acquired Immunodeficiency Syndrome (2004) (0)
- Malnutrition in the tropics. (1988) (0)
- Serotonin and the Carcinoid Syndrome. (1962) (0)
- Drug therapy of hypertension. Present status and recent developments. (1969) (0)
- Long-Term Maintenance Therapy of Established Human Small Cell Variant Lung Carcinoma Implants in Athymic Mice with a Cyclic Regimen of Difluoromethylornithine 1 (2006) (0)
- Method of alleviating withdrawal symptoms us patent 4800209 january 24 1989 (1989) (0)
- Effect of Digitoxin On Creatinine and Histamine Output of the Isolated Heart.∗ (1948) (0)
- INTERACTION BETWEEN NOREPINEPHRINE (NE) AND SEROTONIN (5-HYDROXY-TRYPTAMINE, 5-HT) STORAGE AND RELEASE IN HUMAN PLATELETS IN VITRO (1962) (0)
- Difluoromethylornithine and Standard Trypanocides (0)
- DIAGNOSTIC METHODS FOR SEROTONIN AND HISTAMINE ABNORMALITIES. (1964) (0)
- CONJOINT CLINIC ON SEROTONIN, NOREPINEPHRINE AND TYRAMINE. (1965) (0)
- Chemical Diagnosis of Sympath-adrenal Tumors. (1963) (0)
- Unusual effect of some alpha-mercaptoacrylic acids on metabolism of zinc in the rat. (1977) (0)
- Loss of Taste During Therapy With (2017) (0)
- Some biochemical aspects of treatment and diagnosis of hypertension (1966) (0)
- Lysergic Acid Diethylamide in Patients with Excess Serotonin witk C^xceáá Serotonin (2016) (0)
- SIGNIFICANCE OF URINARY HYDROXYPROLINE IN MAN By DARWINJ (2013) (0)
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