Alexander W. Clowes
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Alexander W. Clowes's Degrees
- Doctorate Medicine University of Washington
- PhD Physiology University of Washington
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(Suggest an Edit or Addition)Alexander W. Clowes's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium. (1983) (1583)
- Mechanisms of stenosis after arterial injury. (1983) (837)
- Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty. (1992) (706)
- Significance of Quiescent Smooth Muscle Migration in the Injured Rat Carotid Artery (1985) (654)
- Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. (1994) (651)
- Results of PREVENT III: a multicenter, randomized trial of edifoligide for the prevention of vein graft failure in lower extremity bypass surgery. (2006) (587)
- Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery. (1989) (456)
- Versican V1 Proteolysis in Human Aorta in Vivo Occurs at the Glu441-Ala442 Bond, a Site That Is Cleaved by Recombinant ADAMTS-1 and ADAMTS-4* (2001) (442)
- Inhibition of Rat Arterial Smooth Muscle Cell Proliferation by Heparin: In Vivo Studies with Anticoagulant and Nonanticoagulant Heparin (1980) (429)
- Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis. (1995) (410)
- Mechanisms of arterial graft healing. Rapid transmural capillary ingrowth provides a source of intimal endothelium and smooth muscle in porous PTFE prostheses. (1986) (370)
- Secondary femoropopliteal reconstruction. (1981) (356)
- Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. (1990) (352)
- Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor. (1996) (334)
- Mechanisms of arterial graft failure. 1. Role of cellular proliferation in early healing of PTFE prostheses. (1985) (317)
- Kinetics of cellular proliferation after arterial injury. III. Endothelial and smooth muscle growth in chronically denuded vessels. (1986) (304)
- Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model. (1998) (303)
- Kinetics of vein graft hyperplasia: association with tangential stress. (1987) (291)
- Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. (1994) (287)
- Prevention of stenosis after vascular reconstruction: pharmacologic control of intimal hyperplasia--a review. (1991) (282)
- Kinetics of Cellular Proliferation after Arterial Injury: IV. Heparin Inhibits Rat Smooth Muscle Mitogenesis and Migration (1986) (275)
- Ruptured abdominal aortic aneurysm: the Harborview experience. (1991) (271)
- Increased blood flow inhibits neointimal hyperplasia in endothelialized vascular grafts. (1991) (260)
- Gamma-interferon regulates vascular smooth muscle proliferation and Ia antigen expression in vivo and in vitro. (1988) (257)
- Effects of growth factors in vivo. I. Cell ingrowth into porous subcutaneous chambers. (1987) (257)
- Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery. (1999) (254)
- Aortic Aneurysm Repair: Reduced Operative Mortality Associated with Maintenance of Optimal Cardiac Performance (1980) (232)
- Intimal lesion formation in rat carotid arteries after endothelial denudation in absence of medial injury. (1990) (219)
- Smooth muscle cell expression of extracellular matrix genes after arterial injury. (1994) (213)
- Inhibition of vascular smooth muscle cell migration by heparin‐like glycosaminoglycans (1984) (211)
- Technical factors affecting autogenous vein graft failure: observations from a large multicenter trial. (2007) (210)
- Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo. (1996) (209)
- Heparin blockade of thrombin-induced smooth muscle cell migration involves inhibition of epidermal growth factor (EGF) receptor transactivation by heparin-binding EGF-like growth factor. (2000) (194)
- Endothelial regeneration. V. Inhibition of endothelial regrowth in arteries of rat and rabbit. (1983) (191)
- Heparin regulates smooth muscle S phase entry in the injured rat carotid artery. (1987) (187)
- Inhibition of smooth muscle cell proliferation in injured rat arteries. Interaction of heparin with basic fibroblast growth factor. (1992) (182)
- Healing of polytetrafluoroethylene arterial grafts is influenced by graft porosity. (1990) (180)
- Regulation of Smooth Muscle Cell Growth in Injured Artery (1989) (179)
- Increased blood flow induces regression of intimal hyperplasia. (1997) (178)
- Long-term follow-up and clinical outcome of carotid restenosis. (1989) (174)
- Disparity in Outcomes of Surgical Revascularization for Limb Salvage: Race and Gender Are Synergistic Determinants of Vein Graft Failure and Limb Loss (2009) (174)
- Primate smooth muscle cell migration from aortic explants is mediated by endogenous platelet-derived growth factor and basic fibroblast growth factor acting through matrix metalloproteinases 2 and 9. (1997) (164)
- The role of duplex scanning and arteriography before carotid endarterectomy: a prospective study. (1993) (162)
- Heparin modulates the composition of the extracellular matrix domain surrounding arterial smooth muscle cells. (1990) (162)
- Smooth muscle cell plasticity: fact or fiction? (2013) (157)
- Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of cultured baboon smooth muscle cells. (1994) (157)
- Endothelial cell injury in cardiovascular surgery: the intimal hyperplastic response. (1997) (155)
- Effects of Angiotensin Converting Enzyme Inhibition With Ciiazapril on Intimal Hyperplasia in Injured Arteries and Vascular Grafts in the Baboon (1991) (151)
- Kinetics of cellular proliferation after arterial injury. II. Inhibition of smooth muscle growth by heparin. (1985) (151)
- Risk factors, medical therapies and perioperative events in limb salvage surgery: observations from the PREVENT III multicenter trial. (2005) (151)
- Kinetics of cellular proliferation after arterial injury. V. Role of acute distension in the induction of smooth muscle proliferation. (1989) (150)
- Arterial smooth muscle cells in vivo: relationship between actin isoform expression and mitogenesis and their modulation by heparin (1988) (147)
- Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1. (1998) (140)
- Mechanisms of arterial graft failure. II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses. (1986) (138)
- Proof of fallout endothelialization of impervious Dacron grafts in the aorta and inferior vena cava of the dog. (1994) (136)
- Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells. (1994) (135)
- Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy. (1992) (134)
- Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes. (1994) (134)
- Operative versus nonoperative management of asymptomatic high-grade internal carotid artery stenosis: improved results with endarterectomy. (1987) (132)
- Time course of flow-induced smooth muscle cell proliferation and intimal thickening in endothelialized baboon vascular grafts. (1994) (131)
- The role of plasminogen, plasminogen activators, and matrix metalloproteinases in primate arterial smooth muscle cell migration. (1996) (122)
- Shear stress regulates smooth muscle proliferation and neointimal thickening in porous polytetrafluoroethylene grafts. (1991) (121)
- Platelet-derived growth factor-BB transactivates the fibroblast growth factor receptor to induce proliferation in human smooth muscle cells. (2006) (118)
- Platelet-Derived Growth Factor-BB–Induced Human Smooth Muscle Cell Proliferation Depends on Basic FGF Release and FGFR-1 Activation (2005) (117)
- Effect of aspirin and dipyridamole on the patency of lower extremity bypass grafts. (1984) (117)
- Acute reductions in blood flow and shear stress induce platelet-derived growth factor-A expression in baboon prosthetic grafts. (1996) (117)
- Female gender and oral anticoagulants are associated with wound complications in lower extremity vein bypass: an analysis of 1404 operations for critical limb ischemia. (2007) (116)
- PDGFbeta receptor blockade inhibits intimal hyperplasia in the baboon. (1999) (114)
- Overexpression of human endothelial nitric oxide synthase in rat vascular smooth muscle cells and in balloon-injured carotid artery. (1998) (111)
- Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation. (1991) (109)
- EGFR Transactivation in the Regulation of SMC Function (2001) (106)
- Retrovirally Mediated Overexpression of Versican V3 by Arterial Smooth Muscle Cells Induces Tropoelastin Synthesis and Elastic Fiber Formation In Vitro and In Neointima After Vascular Injury (2002) (106)
- Endothelial NO/cGMP/VASP Signaling Attenuates Kupffer Cell Activation and Hepatic Insulin Resistance Induced by High-Fat Feeding (2011) (103)
- Failure of heparin to inhibit intimal hyperplasia in injured baboon arteries. The role of heparin-sensitive and -insensitive pathways in the stimulation of smooth muscle cell migration and proliferation. (1995) (101)
- Paracrine effect of vascular smooth muscle cells in the prevention of aortic aneurysm formation. (2002) (101)
- Prospective multicenter study of quality of life before and after lower extremity vein bypass in 1404 patients with critical limb ischemia. (2006) (98)
- The effect of rigid external support on vein graft adaptation to the arterial circulation. (1989) (98)
- Definitive proof of endothelialization of a Dacron arterial prosthesis in a human being. (1995) (93)
- Reduced Vascular Nitric Oxide–cGMP Signaling Contributes to Adipose Tissue Inflammation During High-Fat Feeding (2011) (92)
- Heparin inhibits the expression of tissue-type plasminogen activator by smooth muscle cells in injured rat carotid artery. (1992) (90)
- Raf‐1 is activated by the p38 mitogen‐activated protein kinase inhibitor, SB203580 (1999) (90)
- Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. (1992) (89)
- Endothelial cell injury in cardiovascular surgery: atherosclerosis. (1997) (88)
- Chapter 17 Intimal hyperplasia and graft failure (1993) (88)
- Mechanisms of healing in synthetic grafts. (1987) (88)
- Plasminogen activator inhibitor type 1 and tissue inhibitor of metalloproteinases-2 increase after arterial injury in rats. (1997) (87)
- Thrombin- and Factor Xa–Induced DNA Synthesis Is Mediated by Transactivation of Fibroblast Growth Factor Receptor-1 in Human Vascular Smooth Muscle Cells (2004) (87)
- Inhibition of Versican Synthesis by Antisense Alters Smooth Muscle Cell Phenotype and Induces Elastic Fiber Formation In Vitro and in Neointima After Vessel Injury (2006) (86)
- Mechanisms of inhibition by heparin of vascular smooth muscle cell proliferation and migration. (1993) (83)
- Accuracy of duplex scanning for measurement of arterial volume flow. (1992) (82)
- Expression of collagen, interstitial collagenase, and tissue inhibitor of metalloproteinases-1 in restenosis after carotid endarterectomy. (1996) (81)
- The prevalence and natural history of aortic aneurysms in heart and abdominal organ transplant patients. (2003) (78)
- Surgical and endovascular revision of infrainguinal vein bypass grafts: analysis of midterm outcomes from the PREVENT III trial. (2007) (78)
- Can duplex scanning replace arteriography for lower extremity arterial disease? (1990) (77)
- M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling (2015) (73)
- Activation of metalloproteinases and their association with integrins: an auxiliary apoptotic pathway in human endothelial cells (2002) (73)
- Kinetics of Atherosclerosis: A Stem Cell Model (1985) (72)
- Regional expression of the platelet-derived growth factor and its receptors in a primate graft model of vessel wall assembly. (1993) (69)
- Heparan sulfate proteoglycans mediate a potent inhibitory signal for migration of vascular smooth muscle cells. (1998) (68)
- Syndecan-4 Is Required for Thrombin-induced Migration and Proliferation in Human Vascular Smooth Muscle Cells* (2005) (68)
- Retroviral Overexpression of Decorin Differentially Affects the Response of Arterial Smooth Muscle Cells to Growth Factors (2001) (66)
- Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells. (1997) (65)
- Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. (2004) (65)
- Heparin inhibits collagenase gene expression mediated by phorbol ester-responsive element in primate arterial smooth muscle cells. (1992) (65)
- Immediate and long-term results of carotid endarterectomy. (1989) (64)
- Conventional versus high-porosity polytetrafluoroethylene grafts: clinical evaluation. (1992) (64)
- Concern about safety of carotid angioplasty. (1996) (62)
- Gene therapy for long-term expression of erythropoietin in rats. (1995) (62)
- Local plasminogen activator inhibitor type 1 overexpression in rat carotid artery enhances thrombosis and endothelial regeneration while inhibiting intimal thickening. (2000) (61)
- Angiotensin II induction of osteopontin expression and DNA replication in rat arteries. (1996) (61)
- Atherosclerosis in Rabbit Vein Grafts (1989) (61)
- Local expression of bovine decorin by cell-mediated gene transfer reduces neointimal formation after balloon injury in rats. (2000) (59)
- MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. (2001) (59)
- Vasodilator‐stimulated phosphoprotein is a substrate for protein kinase C (2004) (59)
- Physical properties of lecithin-cerebroside bilayers. (1971) (58)
- Early endothelial coverage of synthetic arterial grafts: porosity revisited. (1987) (58)
- A morphologic and permeability study of luminal smooth muscle cells after arterial injury in the rat. (1978) (57)
- Increased Plasmin and Serine Proteinase Activity During Flow-Induced Intimal Atrophy in Baboon PTFE Grafts (2002) (57)
- Protein Kinase C α Expression Is Required for Heparin Inhibition of Rat Smooth Muscle Cell Proliferation in Vitro and in Vivo* (1996) (57)
- The regulation of p42/p44 mitogen-activated protein kinases in the injured rat carotid artery. (1997) (57)
- Design and Rationale of the PREVENT III Clinical Trial: Edifoligide for the Prevention of Infrainguinal Vein Graft Failure (2005) (55)
- Tissue factor overexpression in rat arterial neointima models thrombosis and progression of advanced atherosclerosis. (2000) (55)
- Absence of enhanced intimal thickening in the response of the carotid arterial wall to endothelial injury in hypercholesterolemic rats. (1976) (54)
- Growth factor gene expression by intimal cells in healing polytetrafluoroethylene grafts. (1990) (52)
- Blockade of the epidermal growth factor receptor decreases intimal hyperplasia in balloon-injured rat carotid artery. (2003) (50)
- Flow-induced neointimal regression in baboon polytetrafluoroethylene grafts is associated with decreased cell proliferation and increased apoptosis. (2002) (48)
- Failure of certain antiplatelet drugs to affect myointimal thickening following arterial endothelial injury in the rat. (1977) (48)
- Heparin decreases activator protein-1 binding to DNA in part by posttranslational modification of Jun B. (1994) (46)
- Loss of expression of the beta subunit of soluble guanylyl cyclase prevents nitric oxide-mediated inhibition of DNA synthesis in smooth muscle cells of old rats. (2000) (44)
- Restenosis after vascular reconstruction. (1994) (44)
- Effect of Platelet-Derived Growth Factor Receptor-α and -β Blockade on Flow-Induced Neointimal Formation in Endothelialized Baboon Vascular Grafts (2000) (43)
- The iliac-origin arterial graft: a useful alternative for iliac occlusive disease. (1985) (43)
- Metalloproteinase blockade by local overexpression of TIMP-1 increases elastin accumulation in rat carotid artery intima. (1998) (41)
- Gene transfer in baboons using prosthetic vascular grafts seeded with retrovirally transduced smooth muscle cells: a model for local and systemic gene therapy. (1994) (41)
- Endothelial regeneration. VI. Chronic nondenuding injury in baboon vascular grafts. (1986) (41)
- Resource utilization in the treatment of critical limb ischemia: The effect of tissue loss, comorbidities, and graft-related events. (2006) (40)
- Mechanisms of Arterial Graft Failure: The Role of Cellular Proliferation (1987) (40)
- Effect of heparin on adaptation of vein grafts to arterial circulation. (1989) (40)
- Graft endothelialization: the role of angiogenic mechanisms. (1991) (39)
- Dacron Patch Infection after Carotid Endarterectomy: Case Report and Review of the Literature (2006) (39)
- Regulation and function of an activation-dependent epitope of the beta 1 integrins in vascular cells after balloon injury in baboon arteries and in vitro. (1996) (39)
- Interleukin-1beta inhibits expression of p21(WAF1/CIP1) and p27(KIP1) and enhances proliferation in response to platelet-derived growth factor-BB in smooth muscle cells. (2002) (38)
- Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cells. (1998) (38)
- Regression of myointimal thickening following carotid endothelial injury and development of aortic foam cell lesions in long term hypercholesterolemic rats. (1977) (37)
- Perlecan inhibits smooth muscle cell adhesion to fibronectin: Role of heparan sulfate (2001) (36)
- Comparison of the Effects of Regional Ischemia , Hypoxia , Hyperkalemia , and Acidosis on Intracellular and Extracellular Potentials and Metabolism in the Isolated Porcine Heart (2005) (35)
- MMP-9 regulates both positively and negatively collagen gel contraction: a nonproteolytic function of MMP-9. (2005) (35)
- Accumulation and Loss of Extracellular Matrix During Shear Stress-mediated Intimal Growth and Regression in Baboon Vascular Grafts (2005) (35)
- Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury. (2008) (34)
- Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis. (2009) (34)
- Vasodilator-Stimulated Phosphoprotein Regulates Proliferation and Growth Inhibition by Nitric Oxide in Vascular Smooth Muscle Cells (2004) (34)
- The role of aspirin in enhancing arterial graft patency. (1986) (34)
- Growth factor production by polytetrafluoroethylene vascular grafts. (1988) (33)
- Cell Death–associated ADAMTS4 and Versican Degradation in Vascular Tissue (2009) (32)
- Physical effects of tetanus toxin on model membranes containing ganglioside. (1972) (32)
- Heparin and Cilazapril Together Inhibit Injury‐Induced Intimal Hyperplasia (1991) (31)
- Regulation of β1-Integrin Function in Cultured Human Vascular Smooth Muscle Cells (1996) (30)
- Syndecan-1: An Inhibitor of Arterial Smooth Muscle Cell Growth and Intimal Hyperplasia (2009) (30)
- Blockade of Smooth Muscle Cell Migration and Proliferation in Baboon Aortic Explants by Interleukin-1β and Tumor Necrosis Factor-α Is Nitric Oxide-Dependent and Nitric Oxide-Independent (2000) (29)
- VASP Increases Hepatic Fatty Acid Oxidation by Activating AMPK in Mice (2013) (29)
- Vasospasm as a cause for claudication in athletes with external iliac artery endofibrosis. (2013) (29)
- Smooth muscle DNA replication in response to angiotensin II is regulated differently in the neointima and media at different times after balloon injury in the rat carotid artery. Role of AT1 receptor expression. (1996) (28)
- Membrane‐type matrix metalloproteinase‐1 and ‐3 activity in primate smooth muscle cells (2001) (28)
- Current concepts in restenosis following balloon angioplasty. (1995) (27)
- Regulation of baboon arterial smooth muscle cell plasminogen activators by heparin and growth factors. (1995) (27)
- Circulating monocytes and in- stent neointima after coronary stent implantation (2005) (26)
- A Possible Role for MMP‐2 and MMP‐9 in the Migration of Primate Arterial Smooth Muscle Cells through Native Matrix (1994) (26)
- Atheromatous changes in expanded polytetrafluoroethylene grafts. (1980) (26)
- Lipoprotein regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in rat liver cell cultures. (1977) (26)
- Disruption of integrin α5β1 signaling does not impair PDGF‐BB‐mediated stimulation of the extracellular signal‐regulated kinase pathway in smooth muscle cells (1997) (26)
- Cultured Arterial Smooth Muscle Cells Maintain Distinct Phenotypes When Implanted Into Carotid Artery (2001) (24)
- Inhibition of smooth muscle cell proliferation by heparin molecules. (1989) (24)
- Bone morphogenetic protein 4: potential regulator of shear stress-induced graft neointimal atrophy. (2006) (24)
- Platelet-derived growth factor and arterial response to injury. (1997) (24)
- Pervanadate inhibits mitogen‐activated protein kinase kinase‐1 in a p38MAPK‐dependent manner (1998) (23)
- Effect of platelet-derived growth factor receptor-alpha and -beta blockade on flow-induced neointimal formation in endothelialized baboon vascular grafts. (2000) (23)
- Cleavage of Focal Adhesion Kinase in Vascular Smooth Muscle Cells Overexpressing Membrane-Type Matrix Metalloproteinases (2004) (23)
- Improving the interface between biomaterials and the blood. The gene therapy approach. (1996) (23)
- Mechanism of long-term degeneration of arterialized vein grafts. (1990) (22)
- Prevention and Management of Recurrent Disease after Arterial Reconstruction: New Prospects for Pharmacological Control (1991) (22)
- Effect of an anti‐PDGF‐β‐receptor‐blocking antibody on restenosis in patients undergoing elective stent placement (2003) (22)
- Management of aortocaval fistula due to abdominal aortic aneurysm. (1979) (22)
- Concomitant blockade of platelet-derived growth factor receptors α and β induces intimal atrophy in baboon PTFE grafts (2004) (22)
- Circulating inflammatory cells are associated with vein graft stenosis. (2011) (21)
- ELASTIN EXPRESSION IN A MODEL OF ACUTE ARTERIAL GRAFT REJECTION (1994) (21)
- Pituitary factors in blood plasma are necessary for smooth muscle cell proliferation in response to injury in vivo. (1992) (21)
- Images in cardiovascular medicine. Serial high-spatial-resolution, multisequence magnetic resonance imaging studies identify fibrous cap rupture and penetrating ulcer into carotid atherosclerotic plaque. (2006) (21)
- Mechanisms of Vascular Atrophy and Fibrous Cap Disruption (2000) (20)
- Concomitant blockade of platelet-derived growth factor receptors alpha and beta induces intimal atrophy in baboon PTFE grafts. (2004) (20)
- Suppression by heparin of injury-induced myointimal thickening. (1978) (20)
- Vascular Gene Therapy in the 21st Century (1997) (20)
- Induction of vascular atrophy as a novel approach to treating restenosis. A review. (2008) (19)
- Unique Cleavage Planes in Frozen Red Cell Membranes 1 (1970) (19)
- Interleukin-1β inhibits PDGF-BB−induced migration by cooperating with PDGF-BB to induce cyclooxygenase-2 expression in baboon aortic smooth muscle cells (2004) (19)
- A single nucleotide polymorphism in the p27(Kip1) gene is associated with primary patency of lower extremity vein bypass grafts. (2013) (19)
- Is smooth muscle growth in primate arteries regulated by endothelial nitric oxide synthase? (1998) (18)
- Low levels of a natural IgM antibody are associated with vein graft stenosis and failure. (2013) (18)
- Pharmacologic inhibition of nitric oxide synthases and cyclooxygenases enhances intimal hyperplasia in balloon-injured rat carotid arteries. (2004) (18)
- Kinetics of vein graft hyperplasia (1986) (17)
- VASP phosphorylation at serine239 regulates the effects of NO on smooth muscle cell invasion and contraction of collagen (2010) (17)
- Regulation of smooth muscle cell proliferation and migration. (1999) (17)
- Profunda femoris bypass for secondary revascularization. (1980) (16)
- γ‐Interferon Regulates Vascular Smooth Muscle Proliferation and Ia Antigen Expression In Vivo and In Vitro (1988) (16)
- Effect of lipoprotein on 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase activity in rat liver cell culture: special suppressant effect of a lipoprotein isolated from hypercholesterolemic rat plasma. (1975) (15)
- Influence of chronic hypertension on injured and uninjured arteries in spontaneously hypertensive rats. (1980) (15)
- Regulation of smooth muscle cell function by heparin. (1992) (15)
- Vasodilator-stimulated phosphoprotein protects against vascular inflammation and insulin resistance. (2014) (15)
- The intimal hyperplastic response (1997) (14)
- Reviving the vascular surgeon-scientist: an interim assessment of the jointly sponsored Lifeline Foundation/National Heart, Lung, and Blood Institute William J. von Liebig Mentored Clinical Scientist Development (K08) Program. (2007) (14)
- A link between smooth muscle cell death and extracellular matrix degradation during vascular atrophy. (2011) (14)
- The effects of different growth factors in subcutaneous wound chambers. (1988) (13)
- Effects of external wrapping and increased blood flow on atrophy of the baboon iliac artery. (2008) (13)
- Aortic length changes during abdominal aortic aneurysm formation, expansion and stabilisation in a rat model. (2010) (13)
- Epidemiology and Pathogenesis of Restenosis (2007) (11)
- The influence of hypertension on injury-induced myointimal thickening. (1980) (10)
- The mitogen-activated protein kinase pathway contributes to vanadate toxicity in vascular smooth muscle cells (1998) (10)
- Disruption of integrin alpha 5 beta 1 signaling does not impair PDGF-BB-mediated stimulation of the extracellular signal-regulated kinase pathway in smooth muscle cells. (1997) (10)
- Regulation of smooth muscle proliferation by heparin in vitro and in vivo. (1987) (10)
- Regulation of beta1-integrin function in cultured human vascular smooth muscle cells. (1996) (10)
- Interleukin-1beta inhibits PDGF-BB-induced migration by cooperating with PDGF-BB to induce cyclooxygenase-2 expression in baboon aortic smooth muscle cells. (2004) (10)
- Extra-anatomical bypass of iliac vein obstruction: use of a synthetic (expanded polytetrafluoroethylene [Goretex]) graft. (1980) (10)
- Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency. (2016) (9)
- Nucleotide and deduced amino acid sequences of baboon urokinase-type plasminogen activator. (1990) (8)
- Inhibition of PDGF-B Induction and Cell Growth by Syndecan-1 Involves the Ubiquitin and SUMO-1 Ligase, Topors (2012) (8)
- Heparin. Will it control intimal thickening after angioplasty? (1992) (8)
- Surgical marking pen dye inhibits saphenous vein cell proliferation and migration in saphenous vein graft tissue. (2016) (8)
- Inhibition by heparin of smooth muscle hyperplasia: Research initiatives in vascular surgery * (1989) (8)
- Arterial wall response to injury and healing (1989) (8)
- JE gene expression in an animal model of acute arterial graft rejection. (1996) (8)
- A single nucleotide polymorphism of cyclin‐dependent kinase inhibitor 1B (p27Kip1) associated with human vein graft failure affects growth of human venous adventitial cells but not smooth muscle cells (2018) (7)
- In Vivo MR Evaluation of Atherosclerosis in Human Carotid Artery with Use of Phased-Array Coils (1996) (7)
- Cell-mediated transfer of proteoglycan genes. (2001) (7)
- G-protein expression and intimal hyperplasia after arterial injury: a role for Galpha(i) proteins. (2001) (7)
- The urokinase receptor mediates basic fibroblast growth factor-dependent smooth muscle cell migration through baboon aortic explants. (2002) (7)
- Arterial injury repair in nonhuman primates-the role of PDGF receptor-beta. (2004) (7)
- Heparin Increases Cell Membrane-Associated Heparan Sulfate Proteoglycan in Balloon-Injured Rat Carotid Artery (1993) (7)
- Cloning and characterization of a cDNA encoding the baboon tissue inhibitor of matrix metalloproteinase-1 (TIMP-1). (1995) (7)
- Vascular Gene Transfer Using Smooth Muscle Cells (1997) (6)
- Kinmonth Memorial Lecture. Vascular Surgical Society of Great Britain and Northern Ireland. London, November 1992. Vascular biology--the new frontier. (1994) (6)
- Control of Smooth Muscle Cell Function by Membrane‐Type Matrix Metalloproteinases (2001) (6)
- Induction of Tissue Inhibitor of Metalloproteinase‐2 in Injured Rat Artery a (1994) (6)
- Localization of proteoheparan sulfate in rat aorta (2004) (6)
- Basic science curriculum in vascular surgery residency. (2001) (5)
- Treatment of acute renal artery occlusion after percutaneous transluminal angioplasty. (1989) (5)
- Efficient gene transfer and durable transgene expression in grafted rabbit veins. (2015) (5)
- Generating antibodies against secreted proteins using vascular smooth muscle cells transduced with replication-defective retrovirus. (1996) (5)
- The Doc and the Duchess: The Life and Legacy of George H. A. Clowes (2016) (4)
- Twentieth anniversary of American Vascular Association/Lifeline Foundation: a celebration. (2008) (3)
- Arterial Smooth Muscle Cells (2005) (3)
- Control of intimal hyperplasia by heparin. (1992) (3)
- Preliminary validation of the Claudication Symptom Instrument (CSI) (2017) (2)
- Proliferation of Vascular Smooth Muscle Cells in the Absence of Platelets. In Vivo Study in Deendothelialized Carotid Arteries of Thrombocytopenic Rats (1990) (2)
- Interleukin-1 Inhibits Expression of p21(WAF1/CIP1) and p27(KIP1) and Enhances Proliferation in Response to Platelet-Derived Growth Factor-BB in Smooth Muscle Cells (2002) (2)
- Interventions in atherosclerosis: a review for surgeons. (1978) (2)
- Tissue Factor Activity in Dialysis Access Grafts. (2016) (1)
- Control of Neointimal Hyperplasia in PTFE Grafts (1997) (1)
- ADAMTS4, tissue plasminogen activator, and hyaluronidase 2 are upregulated while GAS6 is downregulated in two baboon vascular atrophy models (2007) (1)
- Vasospasm as a Novel Mechanism to Explain Claudication in Female Athletes with External Iliac Arterial Endofibrosis (2011) (1)
- Inflammatory Mechanisms of Remodeling in Injured Arteries (1997) (1)
- Interleukin-1 b Inhibits Expression of p 21 ( WAF 1 / CIP 1 ) and p 27 ( KIP 1 ) and Enhances Proliferation in Response to Platelet-Derived Growth Factor-BB in Smooth Muscle Cells (2002) (1)
- Prevention of Lesion Recurrence in Endovascular Devices (1999) (1)
- gene is associated with primary patency of lower extremity vein bypass grafts (2013) (1)
- Effects of wall tension and blood flow on cuff-induced atrophy of the baboon iliac artery (2006) (1)
- Matrix Metalloproteinases in Injured Artery (1997) (1)
- RETROVIRALLY MEDIATED EXPRESSION OF VERSICAN V3 ANTISENSE BY ARTERIAL SMOOTH MUSCLE CELLS SLOWS GROWTH AND MIGRATION AND INDUCES ELASTIC FIBER FORMATION IN VITRO AND IN NEOINTIMA AFTER VESSEL INJURY (2004) (0)
- PDGF (cid:98) Receptor Blockade Inhibits Intimal Hyperplasia in the Baboon (1999) (0)
- Rutherford Claudication Severity Compared to Patient Reported Quality of Life and Function (2015) (0)
- Plasminogen Activator During Migration in Injured Rat Carotid Artery (2005) (0)
- Syndecan‐1 plays an important role in the development of intimal thickening after vascular injury (0)
- antagonist composition for inhibiting hyperplasia inner Using the PDGF and heparin (1995) (0)
- Vascular surgery and vascular gene therapy (1998) (0)
- KINMONTH MEMORIAL LECTURE (2013) (0)
- Abstract 315: Surgical Pen Dye Inhibits Cell Migration From Saphenous Vein Explants (2014) (0)
- Primate smooth muscle cell (SMC) migration is mediated by matrix metalloproteinase (MMP) 9 and by urokinase (uPA) (1996) (0)
- Abstract 440: Increased Migration and Proliferation of Human Venous Valve Wall Smooth Muscle Cells are Mediated by FGF2 (2015) (0)
- Will it Control Intimal Thickening After Angioplasty? (2005) (0)
- Theories of Atherosclerosis (2019) (0)
- 69 – Endothelial Cell and Smooth Muscle Cell Biology in Vascular Disease (2001) (0)
- Cell — Based Gene Delivery: Smooth Muscle Cells as Carriers (1997) (0)
- VASP EXPRESSION RETARDS VASCULAR SMOOTH MUSCLE MIGRATION (2004) (0)
- The building and characterization and “designer intimas” (1994) (0)
- THROMBIN- AND FACTOR-XA-INDUCED PROLIFERATION AND MIGRATION IN HUMAN VASCULAR SMOOTH MUSCLE CELLS ARE MEDIATED BY BASIC FIBROBLAST GROWTH FACTOR AND SYNDECAN-4 (2004) (0)
- Alters Remodeling in the Injured Rat Carotid Artery Matrix Metalloproteinase-9 Overexpression Enhances Vascular Smooth Muscle Cell (1999) (0)
- Heparin increased cell membrane-associated heparan sulfate proteoglycan in balloon-injured rat carotid artery. (1993) (0)
- Roleofplatelets insmoothmuscle cell proliferation andmigration after vascular injury inratcarotid artery (1989) (0)
- Heparin Decreases Activator Protein-1 Binding (2005) (0)
- Subject Index, Vol. 23, 1993 (1993) (0)
- The heparan sulfate chains on perlecan affects smooth muscle cell adhesion and spreading when co-coated with fibronectin (2000) (0)
- Abstract 144: A Single Nucleotide Polymorphism of p27Kip1 Associated with Vein Graft Patency Regulates Expression of p27Kip1 in Both Venous Adventitial Cells and Smooth Muscle Cells but Selectively Regulates Proliferation of Adventitial Cells (2016) (0)
- Potential Association of a Single Nucleotide Polymorphism in the CDNK1B Gene and Carotid Plaque Fibrous Cap Status by MRI (2013) (0)
- Regulation of Intimal Growth and Regression by Blood Flow (1999) (0)
- Abstract 1003: Nitric Oxide-Dependent Phosphorylation of Vasodilator-Stimulated Phosphoprotein Regulates Vascular Smooth Muscle Cell Contraction, Adhesion and Spreading (2006) (0)
- Use of antibodies against PDGF receptors to inhibit hyperplasia of the intima (1994) (0)
- Title Page / Table of Contents, Vol. 23, Supplement 1, 1993 (1993) (0)
- Smooth Muscle Cell Function from the Clinical Perspective: Overview (1995) (0)
- PDGF-BB negatively regulates the expression of perlecan in rat vascular smooth muscle cells (2000) (0)
- Cellular and Molecular Basis of Restenosis (1996) (0)
- Abstract 222: SCARA5 and Suprabasin are Hub Genes of Co-expression Network Modules Associated with Peripheral Vein Graft Patency (2015) (0)
- Composition for inhibiting intimal hyperplasia using PDGF antagonists (1995) (0)
- receptors for the migration and proliferation of cultured baboon smooth muscle Different functions of the platelet-derived growth factor-alpha and - beta (2011) (0)
- Intimal Hyperplasia: TheMechanisms and Treatment of the Response to Arterial Injury (2004) (0)
- 1986 Year book of vascular surgery (1986) (0)
- Basic Science Review for Surgeons (1992) (0)
- p38MAPK inhibits Ras-dependent activation of mitogen-activated protein kinase kinase-1 in oxidative stress signaling (1998) (0)
- Short title: A Role of VASP on hepatic fatty acid oxidation (2013) (0)
- Abstract 221: A Single Nucleotide Polymorphism of p27Kip1 Associated with Vein Graft Patency Regulates Proliferation of Cells Derived from the Outer, but not the Inner, Venous Wall (2015) (0)
- The Doc and the Duchess (2016) (0)
- Abstract 498: A Single Nucleotide Polymorphism in the CDKN1B Gene is Associated With Carotid Plaque Progression (2014) (0)
- Commentary. Circulating monocytes and in-stent neointima after coronary stent implantation. (2005) (0)
- Abstract 249: Delayed Gene Transfer Increases Transgene Expression in Vein Grafts (2013) (0)
- Interleukin-1&bgr; Inhibits Expression of p21(WAF1/CIP1) and p27(KIP1) and Enhances Proliferation in Response to Platelet-Derived Growth Factor-BB in Smooth Muscle Cells (2002) (0)
- Baboon PTFE Grafts Increased Plasmin and Serine Proteinase Activity During Flow-Induced Intimal Atrophy (2002) (0)
- Intimal Hyperplasia — Development and Regression in Response to Fluid Shear (1999) (0)
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What Schools Are Affiliated With Alexander W. Clowes?
Alexander W. Clowes is affiliated with the following schools:
