Arthur W. Nienhuis

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Arthur W. Nienhuis

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Philosophy

Arthur W. Nienhuis's Degrees

Doctorate Medicine University of Amsterdam

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Arthur W. Nienhuis's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. (2011) (1558)
Long-term safety and efficacy of factor IX gene therapy in hemophilia B. (2014) (942)
Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. (1994) (794)
Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. (1992) (505)
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation (1988) (436)
5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia. (1982) (428)
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy. (1989) (412)
Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. (1986) (409)
Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. (1990) (335)
Genotoxicity of retroviral integration in hematopoietic cells. (2006) (312)
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. (1989) (300)
Continuous subcutaenous administration of deferoxamine in patients with iron overload. (1977) (290)
Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major (1993) (280)
Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea. (1990) (278)
Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. (1999) (267)
Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells (2004) (266)
Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins. (2011) (266)
Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells. (1990) (247)
Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. (1997) (245)
Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant. (2013) (231)
Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. (1993) (228)
Hemoglobin switching (1978) (225)
Localization of the human α-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay (1977) (219)
Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice. (2001) (209)
Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood. (2002) (200)
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. (1992) (195)
The functional human dihydrofolate reductase gene. (1984) (186)
Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells. (1990) (178)
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner (1993) (175)
Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques. (2002) (173)
Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells. (1993) (172)
Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. (1987) (166)
Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q− syndrome (1985) (163)
Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system. (2004) (163)
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia (1983) (158)
Developmental regulation of human globin genes. (1985) (156)
The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number. (2003) (155)
Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities. (2011) (152)
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. (2001) (150)
Vitamin C and iron. (1981) (147)
Survival and retrovirus infection of murine hematopoietic stem cells in vitro: effects of 5-FU and method of infection. (1991) (145)
Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. (1994) (144)
Periodic microcirculatory flow in patients with sickle-cell disease. (1984) (143)
Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein. (1995) (142)
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. (1986) (142)
Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. (2000) (141)
Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque. (2006) (138)
Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. (1999) (136)
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. (1987) (136)
Cellular and molecular regulation of hemoglobin switching (1979) (132)
Chromosomal localization of human β globin gene on human chromosome 11 in somatic cell hybrids (1978) (131)
Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor. (1993) (130)
Identification of a stage selector element in the human gamma‐globin gene promoter that fosters preferential interaction with the 5′ HS2 enhancer when in competition with the beta‐promoter. (1992) (127)
Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial. (2011) (127)
Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. (1990) (127)
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. (1994) (126)
Detection of early cardiac dysfunction in patients with severe beta-thalassemia and chronic iron overload. (1979) (126)
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production. (1986) (125)
Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells. (2003) (124)
COOH-terminal-modified interleukin-3 is retained intracellularly and stimulates autocrine growth. (1989) (118)
Echocardiographic abnormalities in patients with transfusion-dependent anemia and secondary myocardial iron deposition. (1978) (115)
Characterization of replication-competent retroviruses from nonhuman primates with virus-induced T-cell lymphomas and observations regarding the mechanism of oncogenesis (1994) (114)
Advances in thalassemia research. (1984) (114)
Pathophysiology and Clinical Manifestations of the β-Thalassemias. (2012) (113)
Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. (1995) (112)
Use of the green fluorescent protein as a marker to identify and track genetically modified hematopoietic cells (1998) (108)
Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia (2004) (108)
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5 (1988) (108)
A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene. (1980) (107)
Treatment with Azacitidine of Patients with End-Stage β-Thalassemia (1993) (105)
Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice. (1988) (105)
Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer. (2011) (103)
Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector. (1991) (103)
Specific prolongation of skin graft survival following retroviral transduction of bone marrow with an allogeneic major histocompatibility complex gene. (1993) (101)
Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. (1994) (97)
RNA processing errors in patients with beta-thalassemia. (1982) (96)
An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer (1996) (95)
Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression (1993) (95)
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. (1983) (93)
Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia. (2004) (93)
Differences in human α-, β- and δ-globin gene expression in monkey kidney cells (1982) (91)
Treatment of Severe Combined Immunodeficiency Disease (SCID) due to Adenosine Deaminase Deficiency with CD34+ Selected Autologous Peripheral Blood Cells Transduced with a Human ADA Gene (Amendment). National Institutes of Health (1993) (90)
Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy. (2001) (90)
An improved method for generating retroviral producer clones for vectors lacking a selectable marker gene. (1998) (89)
Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor. (1994) (88)
Multiple hormone deficiencies in children with hemochromatosis. (1993) (87)
Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia (1989) (86)
Mechanism of DNase I hypersensitive site formation within the human globin locus control region. (1992) (84)
Analysis of lymphocyte subsets in patients with aplastic anaemia (1984) (83)
Retroviral mediated transfer of the human multidrug resistance gene (MDR-1) into hematopoietic stem cells during autologous transplantation after intensive chemotherapy for metastatic breast cancer. (1994) (82)
Efficient gene transfer into human cord blood CD34+ cells and the CD34+CD38− subset using highly purified recombinant adeno-associated viral vector preparations that are free of helper virus and wild-type AAV (2000) (80)
A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. (2010) (80)
Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder (1989) (79)
Antithymocyte globulin reacts with many normal human cell types. (1983) (78)
Therapeutic approaches to hemoglobin switching in treatment of hemoglobinopathies. (1992) (78)
Active conformation of the globin genes in uninduced and induced mouse erythroleukemia cells (1978) (78)
Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor (1993) (77)
Beta O-39 thalassemia gene: a premature termination codon causes beta-mRNA deficiency without affecting cytoplasmic beta-mRNA stability. (1984) (77)
Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector. (2007) (77)
An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells. (1999) (76)
"Silent" nucleotide substitution in a beta+-thalassemia globin gene activates splice site in coding sequence RNA. (1983) (76)
Beta thalassemia: Mutations which affect processing of the β-globin mRNA precursor (1980) (75)
5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin. (1985) (75)
An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. (2008) (74)
Systemic errors in quantitative polymerase chain reaction titration of self-complementary adeno-associated viral vectors and improved alternative methods. (2012) (74)
Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells. (2003) (73)
Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein. (1987) (72)
The regulatory element 3' to the A gamma-globin gene binds to the nuclear matrix and interacts with special A-T-rich binding protein 1 (SATB1), an SAR/MAR-associating region DNA binding protein. (1994) (71)
Private and public autocrine loops in neoplastic cells. (1989) (70)
Adeno-Associated Mediated Gene Transfer for Hemophilia B:8 Year Follow up and Impact of Removing "Empty Viral Particles" on Safety and Efficacy of Gene Transfer (2018) (69)
Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer (1989) (69)
Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes. (1971) (69)
Functional amelioration of murine galactosialidosis by genetically modified bone marrow hematopoietic progenitor cells. (2002) (69)
EVALUATION OF CARDIAC FUNCTION IN PATIENTS WITH THALASSEMIA MAJOR (1980) (68)
Dihydrofolate reductase gene amplification and possible rearrangement in estrogen-responsive methotrexate-resistant human breast cancer cells. (1982) (68)
Development of gene therapy for blood disorders. (2008) (68)
Selective activation of human β - but not γ-globin gene in human fibroblast × mouse erythroleukaemia cell hybrids (1979) (68)
High-level globin gene expression mediated by a recombinant adeno-associated virus genome that contains the 3' gamma globin gene regulatory element and integrates as tandem copies in erythroid cells. (1997) (67)
Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. (1982) (66)
Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. (1984) (63)
Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia. (2004) (61)
Functional correction of T cells derived from patients with the Wiskott–Aldrich syndrome (WAS) by transduction with an oncoretroviral vector encoding the WAS protein (2003) (61)
Mobilization and Mechanism of Transcription of Integrated Self-Inactivating Lentiviral Vectors (2005) (61)
CT Findings in Addison's Disease (1982) (60)
Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector. (1987) (59)
Nemaline myopathy. A histopathologic and histochemical study. (1967) (58)
Evidence of Genetic Heterogeneity in Five Kindreds With Familial Hypertrophic Cardiomyopathy (1992) (58)
Cytogenetic studies in patients with myelofibrosis and myeloid metaplasia (1978) (57)
Computed Tomography in the Diagnosis of Disorders of Excessive Iron Storage of the Liver (1977) (57)
Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells. (2009) (56)
Retroviral transfer and expression of the interleukin-3 gene in hemopoietic cells. (1987) (56)
A functionally active retrovirus vector for gene therapy in Fanconi anemia group C (1994) (54)
Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia. (1993) (53)
Treatment of Diamond‐Blackfan anaemia with haematopoietic growth factors, granulocyte‐macrophage colony stimulating factor and interleukin 3: sustained remissions following IL‐3 (1991) (52)
Transfer of genes into hematopoietic cells using recombinant DNA viruses. (1985) (49)
Development of gene therapy for blood disorders: an update. (2013) (49)
Transfusion haemosiderosis and chelation therapy. (1982) (48)
Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor (1994) (48)
Development of gene therapy for thalassemia. (2012) (47)
Contribution of promoter to tissue-specific expression of the mouse immunoglobulin kappa gene. (1985) (47)
High levels of lymphoid expression of enhanced green fluorescent protein in nonhuman primates transplanted with cytokine-mobilized peripheral blood CD34(+) cells. (2000) (46)
Promoter sequences required for function of the human gamma globin gene in erythroid cells. (1986) (45)
A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system. (1984) (45)
Pharmacological Manipulation of Fetal Hemoglobin Synthesis in Patients with Severe β‐Thalassemia (1985) (45)
A functionally active retrovirus vector for gene therapy in Fanconi anemia group C. (1994) (45)
A trial of recombinant human interleukin‐1 in patients with severe refractory aplastic anaemia (1992) (45)
Gene Therapy for Hemophilia. (2017) (44)
Hemoglobin synthesis in somatic cell hybrids: globin gene expression in hybrids between mouse erythroleukemia and human marrow cells or fibroblasts. (1975) (43)
Hemoglobin messenger RNA from human bone marrow. Isolation and translation in homozygous and heterozygous beta-thalassemia. (1973) (42)
Gene therapy for the hemoglobin disorders: past, present, and future. (2000) (42)
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5. (1988) (42)
Selective isolation of young erythrocytes for transfusion support of thalassemia major patients. (1981) (42)
Single-copy transduction and expression of human gamma-globin in K562 erythroleukemia cells using recombinant adeno-associated virus vectors: the effect of mutations in NF-E2 and GATA-1 binding motifs within the hypersensitivity site 2 enhancer. (1993) (41)
Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors (1996) (41)
Stable gene transfer and tissue‐specific expression of a human globin gene using adenoviral vectors. (1986) (40)
The upstream region of the human gamma-globin gene promoter. Identification and functional analysis of nuclear protein binding sites. (1991) (40)
Disseminated infection caused by Cunninghamella bertholletiae in a patient with beta-thalassemia. Case report and review of the literature. (2020) (40)
New myopathy with mitochondrial enzyme hyperactivity. Histochemical demonstration. (1967) (39)
"Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential. (1986) (39)
Extinction of globin gene expression in human fibroblast × mouse erythroleukemia cell hybrids (1976) (39)
Gene Therapy for Human Hemoglobinopathies (1993) (39)
Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate. (1992) (38)
Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells (1987) (37)
Chromosomal localization and racial distribution of the polymorphic human dihydrofolate reductase pseudogene (DHFRP1). (1988) (37)
WASP- mice exhibit defective immune responses to influenza A virus, Streptococcus pneumoniae, and Mycobacterium bovis BCG. (2005) (37)
High-level erythroid lineage-directed gene expression using globin gene regulatory elements after lentiviral vector-mediated gene transfer into primitive human and murine hematopoietic cells. (2002) (37)
Thalassemia Major: Molecular and Clinical Aspects (1979) (36)
Massive myocardial hemosiderosis: a structure-function conference at the National Heart and Lung Institute. (1975) (36)
Gene therapy for the hemoglobin disorders. (2003) (36)
Computed Tomographic Studies of Thoracic Extramedullary Hematopoiesis (1980) (35)
Hemoglobin switching in sheep and goats: change in functional globin messenger RNA in reticulocytes and bone marrow cells. (1972) (35)
Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with CD34+ selected autologous peripheral blood cells transduced with a human ADA gene. Amendment to clinical research project, Project 90-C-195, January 10, 1992. (1993) (35)
Dysregulated expression of GATA-1 following retrovirus-mediated gene transfer into murine hematopoietic stem cells increases erythropoiesis. (1995) (34)
Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. (1994) (34)
Hematopoietic Growth Factors (1988) (34)
Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes. (1980) (33)
Structure and function of the enhancer 3' to the human A gamma globin gene. (1990) (33)
DNA methylation and globin gene expression in patients treated with 5-azacytidine. (1983) (31)
Strand-selective transcription of globin genes in rabbit erythroid cells and chromatin. (1975) (31)
Gene transfer into hematopoietic stem cells (1991) (30)
Amendment to clinical research projects. Genetic marking with retroviral vectors to study the feasibility of stem cell gene transfer and the biology of hematopoietic reconstitution after autologous transplantation in multiple myeloma, chronic myelogenous leukemia, or metastatic breast cancer. (1993) (30)
Initiation of globin synthesis. Preparation and use of reticulocyte ribosomes retaining initiation region messenger ribonucleic acid fragments. (1972) (30)
Isolation and characterization of a 15-kilobase genomic sequence coding for part of the Pro alpha 2 chain of sheep type I collagen. (1980) (30)
Retroviral-mediated gene transfer into mammalian cells. (1987) (30)
Antithymocyte globulin hypersensitivity in bone marrow failure patients. (1988) (30)
Microcirculatory adaptations in sickle cell anemia: reactive hyperemia response. (1986) (30)
Chromatin structure of the human dihydrofolate reductase gene promoter. Multiple protein-binding sites. (1986) (29)
Current status and prospects for gene therapy (2004) (29)
Preclinical dose-finding study with a liver-tropic, recombinant AAV-2/8 vector in the mouse model of galactosialidosis. (2012) (29)
Gene Therapy 2000. (2000) (28)
[58] Preparation of globin messenger RNA (1974) (28)
A new moderately repetitive DNA sequence family of novel organization. (1987) (28)
Brain glucose metabolism in neurologically normal patients with sickle cell disease. Regional alterations. (1988) (28)
A chromatin insulator blocks interactions between globin regulatory elements and cellular promoters in erythroid cells. (2007) (27)
Gene transfer into hematopoietic cells (1997) (27)
Hemoglobin synthesis in somatic cell hybrids: independent segregation of the human alpha- and beta-globin genes. (1976) (26)
Cell-free transcription of mammalian chromatin. Quantitative measurement of newly synthesized globin messenger RNA sequences. (1975) (26)
Hemoglobins in development and differentiation (1981) (25)
Translation of rabbit haemoglobin messenger RNA by thalassaemic and non-thalassaemic ribosomes. (1971) (25)
Hemoglobin switching in sheep and goats. Preparation and characterization of complementary DNAs specific for the alpha-, beta-, and gamma-globin messenger RNAs of sheep. (1977) (25)
Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow (1978) (25)
Serum sickness and haematopoietic recovery with antithymocyte globulin in bone marrow failure patients (1986) (25)
Hemoglobin switching in sheep and goats. V. Effect of erythropoietin concentration on in vitro erythroid colony growth and globin synthesis (1975) (24)
Myeloproliferative syndrome with sideroblastic anemia and acquired hemoglobin H disease (1980) (24)
Hemoglobin Switching in Sheep and Goats: Occurrence of Hemoglobins A and C in the Same Red Cell (1974) (24)
Evaluation of desferrioxamine and ascorbic acid for the treatment of chronic iron overload. (1976) (23)
Acquired alpha-thalassemia in preleukemia is due to decreased expression of all four alpha-globin genes. (1983) (23)
Early Clinical Trial Results Following Administration of a Low Dose of a Novel Self Complementary Adeno-Associated Viral Vector Encoding Human Factor IX In Two Subjects with Severe Hemophilia B (2010) (23)
Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with a RD114 pseudotyped oncoretroviral vector. (2003) (23)
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. (1978) (23)
Site-specific demethylation and normal chromatin structure of the human dihydrofolate reductase gene promoter after transfection into CHO cells (1987) (23)
Gene Transfer into Hematopoietic Cells: Implications for Cancer Therapy (1994) (23)
Assays to evaluate the genotoxicity of retroviral vectors. (2006) (23)
A human dihydrofolate reductase intronless pseudogene with an Alu repetitive sequence: multiple DNA insertions at a single chromosomal site. (1984) (22)
Structurally diverse molecular deletions in the beta-globin gene cluster exhibit an identical phenotype on interaction with the beta S-gene. (1985) (22)
Only the promoter region of the constitutively expressed normal and amplified human dihydrofolate reductase gene is DNase I hypersensitive and undermethylated. (1985) (22)
Novel therapeutic approaches in sickle cell disease. (2002) (22)
Hemoglobin switching in sheep. Isolation of the fetal gamma-globin gene and demonstration that the fetal gamma- and adult beta A-globin genes lie within eight kilobase segments of homologous DNA. (1981) (22)
15 The Hematopoietic System as a Target for Gene Therapy (1999) (22)
Generation of a lentiviral vector producer cell clone for human Wiskott-Aldrich syndrome gene therapy (2015) (21)
Cell-free hemoglobin synthesis in beta-thalassemia. (1970) (20)
Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins. (2010) (20)
Hemoglobin switching in sheep. (1980) (20)
Hemoglobin switching in sheep and goats. VI. Commitment of erythroid colony-forming cells to the synthesis of betaC globin (1976) (20)
Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castleman's disease. (1990) (20)
Autocrine expression of both endostatin and green fluorescent protein provides a synergistic antitumor effect in a murine neuroblastoma model (2001) (19)
Mechanism of kinase activation in the receptor for colony-stimulating factor 1. (1990) (19)
Gene expression. Vol. 2: Eucaryotic chromosomes (1975) (19)
Comparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors. (2013) (19)
Correction of the murine Wiskott-Aldrich syndrome phenotype by hematopoietic stem cell transplantation. (2002) (18)
Conjunctival sign in sickle cell anaemia: an in-vivo correlate of the extent of red cell heterogeneity. (1985) (18)
Hemogloblin switching in sheep and goats: erythropoietin-dependent synthesis of hemoglobin C in goat bone-marrow cultures. (1973) (18)
Our journey to successful gene therapy for hemophilia B. (2014) (17)
A trial of immunotherapy in aplastic anemia and pure red cell aplasia (1983) (17)
Pathophysiology and Clinical Manifestations of the b -Thalassemias (2012) (17)
Gene transfer and expression in nonhuman primates using retroviral vectors. (1986) (17)
Induction of specific tolerance to MHC-disparate allografts through genetic engineering. (1993) (17)
The asynchrony of γ- and β-chain synthesis during human erythroid cell maturation: III. γ- and β-mRNA in immature and mature erythroid clones (1981) (17)
Purified GPI-anchored CD4DAF as a receptor for HIV-mediated gene transfer. (1994) (16)
Developmental control of globin gene expression. Proceedings of the Fifth Conference on Hemoglobin Switching. Airlie, Virginia, September 28-October 1, 1986. (1987) (16)
Bone marrow transplantation for thalassemia. (1987) (16)
Introduction of an activated RAS oncogene into murine bone marrow lymphoid progenitors via retroviral gene transfer results in thymic lymphomas. (1991) (15)
Multiple myeloma. New approaches to therapy. (1993) (14)
Induction of hemoglobin F synthesis in patients with beta thalassemia. (1985) (14)
Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector (2016) (14)
Stability of the individual globin genes during erythroid differentiation. (1977) (14)
Hemoglobin switching in sheep: Commitment of erythroid stem cells to expression of the βC-globin gene and accumulation of βC-globin mRNA (1978) (14)
Variable pattern of jun and fos gene expression in different hematopoietic cell lines during interleukin 3-induced entry into the cell cycle. (1992) (13)
Current status of gene therapy for hemophilia. (2003) (12)
Hemoglobin switching in sheep and goats: induction of hemoglobin C synthesis in cultures of sheep fetal erythroid cells. (1977) (12)
Structure and expression of human globin genes introduced into mouse fibroblasts. (1981) (12)
Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis (2000) (12)
Pilot study of high dose ICE (ifosfamide, carboplatin, etoposide) chemotherapy and autologous bone marrow transplant (ABMT) with neoR-transduced bone marrow and peripheral blood stem cells in patients with metastatic breast cancer. (1993) (12)
Differences in human alpha-, beta- and delta-globin gene expression in monkey kidney cells. (1982) (12)
Functional profile of the human fetal gamma-globin gene upstream promoter region. (1992) (11)
Targeted Integration of a Recombinant Globin Gene Adeno‐Associated Viral Vector into Human Chromosome 19 a (1998) (11)
Transfer of human and murine globin-gene sequences into transgenic mice. (1985) (11)
Systemic Errors in Quantitative Polymerase Chain Reaction Titration of Self-Complementary Adeno-Associated Viral Vectors and Improved Alternative Methods (2011) (11)
alpha-and beta-Globin complementary deoxyribonucleic acids of human and rabbit. Specificity of hybridization. (1975) (11)
A weak upstream promoter gives rise to long human β-globin RNA molecules (1983) (11)
Hepatocellular adenoma in a young woman with beta-thalassemia and secondary iron overload. (1981) (10)
Functional dissection of structural domains in the receptor for colony-stimulating factor-1. (1992) (10)
Tolerance induction using autologous bone marrow modified with an allogeneic class I MHC gene. (1993) (10)
The combination of IL-3 and IL-6 enhances retrovirus mediated gene transfer into hematopoietic stem cells. (1990) (10)
Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes. (1987) (9)
The human homolog of the Moloney leukemia virus integration 2 locus (MLV12) maps to band p14 of chromosome 5. (1989) (9)
Hemoglobin switching in sheep. Cloning and characterization of the beta A and beta-like embryonic globin genes from genomic DNA. (1980) (9)
Development of a High‐Titer Retrovirus Producer Cell Line and Strategies for Retrovirus‐mediated Gene Transfer into Rhesus Monkey Hematopoietic Stem Cells (1990) (9)
The asynchrony of gamma- and beta-chain synthesis during human erythroid cell maturation. III. gamma- and beta-mRNA in immature and mature erythroid clones. (1981) (8)
Hemoglobin switching in sheep. Synthesis, cloning, and characterization of DNA sequences coding for the beta B, beta C, and gamma-globin mRNAs. (1979) (8)
OVERVIEW: MECHANISMS OF THE REGULATION OF HEMOGLOBIN SYNTHESIS AT THE CELLULAR LEVEL (1980) (8)
In vivo selection to improve gene therapy of hematopoietic disorders. (2002) (8)
Experimental approaches for the study of hemoglobin switching : proceedings of the Fourth Conference on Hemoglobin Switching, October 1-3, 1984 (1985) (8)
Induction of hemoglobin C synthesis in sheep: characterization of the "switching" stem cell. (1979) (8)
Cis-acting sequences that affect the expression of the human fetal gamma-globin genes. (1985) (7)
Localization and characterization of the DNase I-hypersensitive site II (HS II) enhancer. A critical regulatory element within the beta-globin locus-activating region. (1990) (7)
Treatment of primary hemochromatosis with deferoxamine. (1979) (7)
Hemoglobin switching in sheep: a comparison of the erythropoietin-induced switch to HbC and the fetal to adult hemoglobin switch. (1980) (7)
Manipulation of HbF production with hematopoietic growth factors. (1989) (7)
Hemoglobin switching in sheep. Quantitation of betaA- and betaC-mRNA sequences in nuclear and cytoplasmic RNA during the HbA to HbC switch. (1978) (6)
Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia. (2017) (6)
Adeno-Associated Viral Vector Mediated Gene Transfer for Hemophilia B (2011) (6)
Stimulation of hemoglobin C synthesis by erythropoietin in fetal and neonatal sheep. (1979) (6)
Induction of fetal hemoglobin in sickle cell patients by hydroxyurea: the N.I.H. experience. (1989) (6)
Initiation of Globin Synthesis in β-Thalassemia (1973) (6)
CELL‐FREE TRANSCRIPTION OF HUMAN BONE MARROW CHROMATIN (1974) (5)
High level of fetal-globin reactivation by designed transcriptional activator-like effector. (2020) (5)
Blast colonies containing hemopoietic progenitor cells can give rise to Abelson virus (A-MuLV)-transformed cell lines. (1988) (5)
Hemoglobin: Molecular, genetic and clinical aspects By H. F. Bunn and B. G. Forget. Philadelphia: W. B. Saunders Company. (1986). 690 pp. $99.00 (1987) (5)
Pharmacologic manipulation of fetal hemoglobin synthesis. (1985) (5)
Analysis of globin gene structure in patients with beta thalassemia by restriction endonuclease mapping. (1981) (5)
Expression of human beta globin genes introduced into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer. (1989) (4)
Somatic Gene Therapy for X-Linked Severe Combined Immunodeficiency Using a Self-Inactivating Modified Gammaretroviral Vector Results in An Improved Preclinical Safety Profile and Early Clinical Efficacy in a Human Patient (2011) (4)
A method for the deionization of bovine serum albumin. (1975) (4)
Introduction and expression of human beta globin genes into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer. (1989) (4)
Trial of Antisense RNA Inhibition of HIV Replication and Gene Expression (1991) (4)
Gene transfer into hematopoietic cells. (1996) (4)
Cellular and molecular studies on globin gene expression. (1978) (4)
Chelation therapy for transfusion-dependent adults. (1983) (4)
Activation and inactivation of genes determining hemoglobin types (1975) (4)
Erratum: Recombinant adeno-associated virus (rAAV)-mediated expression of a human γ-globin gene in human progenitor-derived erythroid cells (Proceedings of the National Academy of Science of the United States of America (October 1, 1994) 91:21 (10183-10187)) (1995) (4)
primary human adult erythroblasts -globin gene promoters enhances fetal hemoglobin production in γ A zinc-finger transcriptional activator designed to interact with the (2011) (4)
A novel form of human polymorphism involving the hDHFR-psi 1 pseudogene identifies three RFLPs (1987) (3)
Assessment of Changes in Gene Expression Caused by Insertions of a Globin Lentiviral Vector Containing Globin Regulatory Elements or a Lentiviral Vector Containing Retroviral LTR Elements. (2004) (3)
Safety of intensive chelation therapy. (1977) (3)
Plasma cell infiltration of the conjunctiva associated with pancytopenia, dermatitis, and polyclonal gammopathy. (1976) (3)
A weak upstream promoter gives rise to long human beta-globin RNA molecules. (1983) (3)
5-AZACYTIDINE FOR BETA-THALASSAEMIA? (1983) (3)
1059. The Influence of a Chromatin Insulator on Interactions between Globin Regulatory Elements and Cellular Promoters in Erythroid Cells (2006) (3)
Antisense RNA inhibition of hematopoietic growth factor production. (1991) (3)
Cellular Immune Responses To Vector In a Gene Therapy Trial For Hemophilia B Using An AAV8 Self-Complementary Factor IX Vector (2013) (3)
The identification of hematopoietic-specific regulatory elements for WASp gene expression (2016) (3)
diminish the risk for proto-oncogene activation An experimental system for the evaluation of retroviral vector design to (2009) (2)
Retroviral Vector‐mediated Gene Transfer and Expression in Nonhuman Primates Following Autologous Bone Marrow Transplantation a (1987) (2)
Study of markers of human erythroid differentiation in hybrid cells (1976) (2)
707. Retroviral insertion site analysis in rhesus macaques transplanted with CD34+ hematopoietic stem cells transduced with a simian immunodeficiency virus-based lentiviral vector (2004) (2)
The growing clinical impact of gene therapy. (2008) (2)
Activation of the Human jl-Globin Promoter in K 562 Cells by DNA Sequences 5 ' to the Fetal Ay-or Embryonic t-Globin Genes (2013) (2)
Long-Term In Vivo Expression of a Murine Adenosine Deaminase Gene in Rhesus Monkey Hematopoietic Cells of Multiple Lineages After Retroviral Mediated Gene Transfer Into CD 34 + Bone Marrow Cells (2003) (2)
387. Myeloid Sarcoma Associated with Gene Marking of Hematopoietic Stem Cells in a Rhesus Macaque (2005) (2)
Selective activation of human beta-but not gamma-globin gene in human fibroblast x mouse erythroleukaemia cell hybrids. (1979) (2)
Stable Factor IX Activity Following AAV-Mediated Gene Transfer in Patients with Severe Hemophilia B (2012) (2)
102. Activation of the LMO2 Gene in Human Lymphoid Cells by rAAV-Mediated Targeted Insertion of a Single LTR Expression Cassette into the First Intron (2006) (2)
Acquired a-thalassemia in preleukemia is due to decreased expression of all four a-globin genes (1999) (2)
Trans-acting factors are responsible for the lack of beta-globin gene expression in K562 cells. (1985) (2)
166. Lentiviral Hematopoietic Stem Cell Gene Therapy for Sjögren-Larsson Syndrome (2016) (2)
Gene Therapy for Hemophilia. (2016) (2)
Preparation of globin messenger RNA. (1974) (1)
Long-Term Polyclonal and Stable Gene Transfer into Rhesus Repopulating Hematopoietic Stem Cells Using a Simian Immunodeficiency Virus-Based Lentiviral Vector System. (2006) (1)
A Zinc-Finger Transcriptional Activator Designed to Interact with the Gamma-Globin Gene Promoters Enhances Fetal Hemoglobin Production in Erythroid Cells Derived From Normal and Beta-Thalassemic CD34+ Cells. (2009) (1)
88Genotoxicity of retroviral integration (2007) (1)
530. Lentiviral Vector Particles Pseudotyped with Wild-Type Baboon Endogenous Retrovirus (BAEV) Glycoprotein Outperform VSV-G Particles in Transducing Human CD34+ Cells Isolated from Cytokine-Mobilized Peripheral Blood or Bone Marrow (2016) (1)
Eighth Cooley's Anemia Symposium: Summation and Perspective (2005) (1)
Traumatic cardiac hemolytic anemia: a late complication of a Starr-Edwards mitral valve prosthesis. (1979) (1)
Silent " nucleotide substitution in a , B-thalassemia globin gene activates splice site in coding sequence RNA ( RNA processing / mRNA / expression vector / gene cloning / mutation ) (1)
Initiation of globin synthesis in beta-thalassemia. (1973) (1)
Transcription of chromatin with prokaryotic and eukaryotic polymerases. (1978) (1)
SUSTAINED HIGH LEVEL EXPRESSION OF HUMAN FIX FOLLOWING LIVER TARGETED DELIVERY OF RECOMBINANT ADENO-ASSOCIATED VIRUS ENCODING THE HUMAN FIX GENE IN RHESUS MACAQUES (2002) (1)
Methods for the development and analysis of erythroid colonies grown in plasma clot cultures. (1976) (1)
"Silent" nucleotide substitution in codon 24 of a beta+ thalassemia globin gene activates splice site in coding sequence RNA. (1983) (1)
AAV-mediated gene transfer in patients with severe hemophilia B: Longer follow-up and expansion of the high dose cohort (2013) (1)
Regulated expression of human globin genes following transfer with retroviral vectors. (1987) (1)
A new technique for mapping the human hemoglobin genes. (1976) (1)
What are the current limitations for HSC transduction? How can we overcome them? (Discussion) (1997) (1)
Hematopoietic growth factors: biologic complexity and clinical promise. (1988) (1)
Human and Mouse Globin-Gene Sequences Introduced into Mice by Microinjection of Fertilized Mouse Eggs (1984) (1)
Molecular genetics : an overview (1987) (1)
Tetralogy of Fallot with hypoxemia in a patient with beta thalassemia intermedia. (1978) (1)
Hemoglobin switching in sheep: only the gamma gene is in the active conformation in fetal liver but all the beta and gamma genes are in the active conformation in bone marrow. (1978) (1)
Hemoglobin switching : proceedings of the Sixth Conference on Hemoglobin Switching, held in Airlie, Virginia, September 24-27, 1988 (1989) (1)
Multiple Integration Events into Several Putative Oncogenes Was Required To Cause Leukemogenesis in Two Primate Recipients of RCR Contaminated Stem-Cells. (2004) (1)
Liver targeted delivery of recombinant adeno-associated virus (rAAV) serotype 5 vectors leads to sustained therapeutic expression of human factor IX (hFIX) in non-human primates previously sensitized to rAAV2 vectors. (2003) (1)
Structure of the globin gene in differentiating erythroid cells. (1978) (1)
A phase i/ii clinical trial entailing peripheral vein administration of a novel self complementary adeno-associated viral vector encoding human fix for haemophilia b gene therapy (2011) (1)
George Stamatoyannopoulos (1934–2018) (2018) (1)
Transcriptional regulation of human gamma globin gene expression. (1989) (1)
Tissue and developmental specificity of globin gene promoters: gene expression in human and mouse erythroleukemia and nonerythroid cells. (1987) (1)
10. The Effect of Globin Locus Control Region (LCR) Elements or the MSCV-LTR on Promoter Trapping by Integrated Lentiviral Vector Genomes (2005) (1)
250. Cell-free transcription of mammalian globin genes (1974) (1)
Transfer of genes in hematopoietic cells with retroviral vectors. (1988) (0)
686. Forced Fetal-Globin Reactivation Mediated by the TALE-ldb1 Fusion Protein (2016) (0)
Subject Index Vol. 16, 1976 (1976) (0)
Regulation of hemoglobin switching in sheep: cellular and molecular aspects. (1978) (0)
Gamma-globin lentiviral vector-mediated stem cell gene therapy of beta-thalassemia and sickle cell disease (2008) (0)
Organization and expression of globin genes : [proceedings of the Second Conference on Hemoglobin Switching, held at Airlie House, Virginia, June 22-26, 1980] (1981) (0)
Hemoglobin switching: a new experimental model. (1978) (0)
555. Distribution of AAV8 Particles in Cell Lysates and Supernatants Changes with Time and Is Dependent on the Vector Genome (2015) (0)
Structure and function of the enhancer 3' to the human Aoy globin gene (2003) (0)
ENCODING THE HUMAN FIX GENE IN RHESUS MACAQUES TARGETED DELIVERY OF RECOMBINANT ADENO-ASSOCIATED VIRUS SUSTAINED HIGH LEVEL EXPRESSION OF HUMAN FIX FOLLOWING LIVER (2013) (0)
variant administration of rAAV vector encoding a novel human factor VIII Therapeutic levels of FVIII following a single peripheral vein (2014) (0)
Dose response results of self complementary adeno‐associated virus (AAV) vector‐mediated factor IX gene transfer in non‐human primates (2009) (0)
mediated gene transfer into repopulating hematopoietic cells - Wiskott-Aldrich syndrome are corrected by oncoretroviral vector mediated immunity to influenza virus in murine - (2013) (0)
Genes, Blood and Courage: A Boy Called Immortal Sword (1996) (0)
ISOLATION AND CHARACTERIZATION OF GENOMIC DNA SEQUENCES CODING FOR THE PRO α2 CHAIN OF SHEEP TYPE I PROCOLLAGEN (1980) (0)
Activation of the LMO2 gene in human lymphoid cells by targeted insertion of a single retroviral LTR expression cassette into the first intron (2007) (0)
Long term safety and efficacy of a novel self-complementary adeno-associated viral vector encoding human FIX in patients with severe haemophilia B (2014) (0)
An integrated funding mechanism for clinical trials in human gene therapy. (2009) (0)
Haemoglobin Disorders: Gene Therapy (2006) (0)
RNA processing errors in patients with , 8 thalassemia ( Si nuclease mapping / M 13 phage / splicing ) (0)
Hemoglobin Synthesis in Somatic Cell Hy Hybrids Between Mouse Erythroleukemia (2016) (0)
chromosome 5 The human genes for GM-CSF and IL 3 are closely linked in tandem on (2011) (0)
Lentiviral vectors for the treatment of Wiskott–Aldrich syndrome (2005) (0)
Regulation of Globin Gene Expression (2008) (0)
Developing Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome. (2004) (0)
Lentiviral Vector-Mediated Transfer of the Gamma-Globin Gene Into Normal and Beta-Thalassemic Human CD34+ Cells Results in Potentially Therapeutic Levels of Fetal Hemoglobin in Erythroid Progeny. (2009) (0)
Disorders of Hemoglobin: Prospects for Gene Therapy of Sickle Cell Disease and Thalassemia (2009) (0)
68. Evidence for Correction of Mutations in the c-Kit Gene by rAAV Mediated Gene Targeting in W/Wv Mice (2006) (0)
A new technique for mapping the human hemoglobin genes. (1976) (0)
Blood's 70th anniversary: 1988-1992. (2016) (0)
Gene Therapy Targeted to Stem Cells-An Update (2009) (0)
extent of red cell heterogeneity . anaemia : an in-vivo correlate of the Conjunctival sign in sickle cell (0)
5-AZACYTIDINE FOR BETA-THALASSAEMIA? (1983) (0)
Ninth Cooley's Anemia Symposium: summary and perspective (2010) (0)
Gene: A Premature Termination (2017) (0)
The Effect of a Chromatin Insulator (5′cHS4) on Enhanced Expression of the LMO2 Proto-Oncogene by an Oncoretroviral Long Terminal Repeat. (2006) (0)
Signal-averaged electrocardiography improves patient characterization in hypertrophic cardiomyopathy and aids localization of a disease gene to chromosome 2p in a linkage analysis study (1991) (0)
therapeutic opportunities Transcriptional regulation of fetal to adult hemoglobin switching: new (2012) (0)
Regulatory regions flanking the human fetal gamma-globin genes. (1989) (0)
179. Oncoretroviral Vector-Mediated Gene Therapy for Murine WAS Fails to Correct Most of the Deficient Biological Responses to S. pneumonia or M. bovis (2004) (0)
Globin gene expression and hematopoietic differentiation. Proceedings of the Third Conference on Hemoglobin Switching. September 12-15, 1982. (1983) (0)
Effect of erythropoietin on hemoglobin synthesis. (1977) (0)
Identification of a further stage-selector element in the 5' untranslated region of the human A gamma-globin gene (1995) (0)
5. Evaluation of the Genotoxic Potential of a Self-Inactivating |[gamma]|-Globin Lentiviral Vector (2004) (0)
Regulatory Regions Flanking the Human Fetal γ‐Globin Genes (1989) (0)
289. Safe and Effective Gene Therapy for Wiskott – Aldrich Syndrome Using an Insulated Lentiviral Vector (2015) (0)
bone marrow hematopoietic progenitor cells Functional amelioration of murine galactosialidosis by genetically modified (2013) (0)
Corrigendum: Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein (The EMBO Journal (1995) 14 (97-105)) (1995) (0)
Growth of erythroid colonies from mammalian bone marrow. (1974) (0)
831. Evaluation of Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome (2005) (0)
93. Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal Repeat (2005) (0)
Regulation of Human Globin Gene Expression after Gene Transfer (1981) (0)
Relative stability of aand f 3-globin messenger RNAs in homozygous d + thalassemia ( nuclear RNA / complementary DNA / ' y mRNA / erythroid cells ) (0)
Molecular defects in beta-thalassemia. (1982) (0)
Gene transfer into hematopoietic stem cells. (1991) (0)
Hemogloblin Switching inSheepandGoats: Erythropoietin-Dependent Synthesis ofHemoglobin CinGoatBone-Marrow Cultures* (geneswitching/OA globin/carboxymethylcellulose chromatography/blood/anemia) (1978) (0)
IDENTIFICATION OF DEFECTIVE GLOBIN mRNA IN MEL × FIBROBLAST HYBRID CELLS (1982) (0)
Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal Repeat. (2004) (0)
Regulation of the individual globin genes. (1978) (0)

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University College London