Arthur Z. Eisen
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Molecular Biology
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Philosophy Biology
Arthur Z. Eisen's Degrees
- PhD Biochemistry University of California, Berkeley
- Doctorate Medicine University of California, San Francisco
Why Is Arthur Z. Eisen Influential?
(Suggest an Edit or Addition)Arthur Z. Eisen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. (1989) (1066)
- H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. (1988) (1003)
- Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. (1989) (601)
- Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. (1989) (596)
- Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. (1986) (567)
- Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. (1990) (469)
- Integrin α2β1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells (1991) (368)
- The collagen substrate specificity of human skin fibroblast collagenase. (1981) (340)
- Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures. (1977) (315)
- METHOTREXATE THERAPY IN PSORIATIC ARTHRITIS; DOUBLE-BLIND STUDY ON 21 PATIENTS. (1964) (278)
- Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. (1987) (275)
- Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. (1991) (253)
- Scleroderma: increased biosynthesis of triple-helical type I and type III procollagens associated with unaltered expression of collagenase by skin fibroblasts in culture. (1979) (237)
- Collagenase production by human skin fibroblasts. (1975) (228)
- Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type. (1980) (218)
- Cutaneous mycobacteriosis: analysis of 34 cases with a new classification of the disease. (1981) (202)
- Human skin collagenase. Isolation and mechanism of attack on the collagen molecule. (1968) (188)
- Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin. (1983) (179)
- Quantitation and immunocytochemical localization of human skin collagenase in basal cell carcinoma. (1977) (164)
- Cleavage of type VII collagen by interstitial collagenase and type IV collagenase (gelatinase) derived from human skin. (1989) (148)
- Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. (1994) (147)
- The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products. (1987) (145)
- Mycosis fungoides. Natural history and aspects of its relationship to other malignant lymphomas. (1963) (144)
- Human skin fibroblast collagenase: interaction with substrate and inhibitor. (1985) (143)
- Purification and properties of a gelatin-specific neutral protease from human skin. (1981) (140)
- A specific inhibitor of vertebrate collagenase produced by human skin fibroblasts. (1979) (135)
- Human skin fibroblast collagenase: chemical properties of precursor and active forms. (1978) (132)
- Human skin collagenase: relationship to the pathogenesis of epidermolysis bullosa dystrophica. (1969) (130)
- The role of human skin collagenase in epidermolysis bullosa. (1977) (121)
- The role of epithelium and mesenchyme in the production of a collagenolytic enzyme and a hyaluronidase in the anuran tadpole. (1965) (120)
- Morphea and lichen sclerosus et atrophicus. Clinical and histopathologic studies in patients with combined features. (1980) (117)
- Characteristics of the action of human skin fibroblast collagenase on fibrillar collagen. (1980) (117)
- Familial cutaneous collagenoma: genetic studies on a family * (1979) (117)
- Recessive dystrophic epidermolysis bullosa. Evidence for increased collagenase as a genetic characteristic in cell culture (1978) (111)
- Animal and human collagenases. (1970) (111)
- Structure and organization of mammalian stratum corneum. (1971) (109)
- Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. (1986) (109)
- Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells. (1991) (105)
- Human skin fibroblast collagenase. Assessment of activation energy and deuterium isotope effect with collagenous substrates. (1981) (103)
- Human skin collagenase. The role of serum alpha-globulins in the control of activity in vivo and in vitro. (1971) (100)
- Uric acid metabolism in psoriasis. (1961) (100)
- Human skin collagenase: localization and distribution in normal human skin. (1969) (100)
- Inhibition of human skin collagenase by human serum. (1970) (98)
- Enhanced collagenase production by fibroblasts derived from human basal cell carcinomas. (1979) (97)
- A GENERAL METHOD FOR THE ISOLATION AND PURIFICATION OF PHOSVITIN FROM VERTEBRATE EGGS (1966) (91)
- Cleavage specificity of human skin type IV collagenase (gelatinase). Identification of cleavage sites in type I gelatin, with confirmation using synthetic peptides. (1990) (90)
- A collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator. Purification and properties. (1973) (87)
- Regulation of human skin collagenase activity by hydrocortisone and dexamethasone in organ culture. (1974) (86)
- Matrix metalloproteinase (MMP)-9 type IV collagenase/gelatinase implicated in the pathogenesis of Sjögren's syndrome. (1998) (86)
- Responses of the superficial portion of the human pilosebaceous apparatus to controlled injury. (1955) (84)
- Studies on uterine collagenase in tissue culture. II. Effect of steroid hormones on enzyme production. (1971) (83)
- Matrilysin (PUMP) correlates with dermal invasion during appendageal development and cutaneous neoplasia. (1994) (82)
- Retinoic acid inhibition of collagenase and gelatinase expression in human skin fibroblast cultures. Evidence for a dual mechanism. (1983) (81)
- The gelatinolytic activity of human skin fibroblast collagenase. (1982) (79)
- Inhibition of collagen degradative enzymes by retinoic acid in vitro. (1982) (77)
- Platelet-derived collagenase inhibitor: characterization and subcellular localization. (1985) (76)
- The structure of the human skin fibroblast collagenase gene. (1988) (76)
- Stimulation of skin fibroblast collagenase production by a cytokine derived from basal cell carcinomas. (1985) (75)
- Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma. (1992) (72)
- An extractable collagenase from crustacean hepatopancreas. (1969) (69)
- Verrucous lesions in patients with discoid lupus erythematosus (1978) (68)
- Leukocyte and lymphocyte cyclic AMP responses in atopic eczema. (1977) (68)
- Histology and cytochemistry of human skin. VI. The distribution of sulfhydryl and disulfide groups. (1954) (66)
- Collagenase in human cornea: immunologic localization. (1980) (66)
- Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts. (1997) (65)
- Localization of 92-kDa type IV collagenase in human skin tumors: comparison with normal human fetal and adult skin. (1993) (64)
- Amino acid sequence of a collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator. (1980) (63)
- Extracellular matrix metalloproteinases around loose total hip prostheses. (1994) (62)
- Maffucci's syndrome: a mesenchymal dysplasia and multiple tumour syndrome (1977) (62)
- Immunologic relationship of a purified human skin collagenase to other human and animal collagenases. (1970) (61)
- Pseudouridine metabolism. III. Studies with isotopically labeled pseudouridine. (1962) (61)
- Enzyme-linked immunosorbent assay for human skin collagenase. (1983) (60)
- The function of Ca+ in the action of mammalian collagenases. (1976) (60)
- THE ULTRASTRUCTURAL LOCALIZATION OF ACID PHOSPHATASE IN HUMAN EPIDERMIS. (1964) (56)
- Immunocytochemical localization of collagenase in human skin and fibroblasts in monolayer culture. (1974) (56)
- The structure and tensile properties of the skin of tight-skin (Tsk) mutant mice. (1978) (55)
- Radioimmunoassay of human collagenase. Specificity of the assay and quantitative determination of in vivo and in vitro human skin collagenase. (1972) (55)
- Matrix metalloproteinases in blood vessel development in human fetal skin and in cutaneous tumors. (1995) (55)
- Lipoid proteinosis: in vivo and in vitro evidence for a lysosomal storage disease. (1981) (54)
- Decreased collagenase production by regional fibroblasts cultured from skin of a patient with connective tissue nevi of the collagen type. (1982) (53)
- Febrile Ulceronecrotic Mucha‐Habermann's Disease with Interstitial Pneumonitis (1979) (53)
- Evidence for mammalian collagenases as zinc ion metalloenzymes. (1977) (51)
- A sensitive microassay for prolyl hydroxylase: activity in normal and psoriatic skin. (1973) (50)
- Tissue stress and tumor promotion. Possible relevance to epidermolysis bullosa. (1988) (49)
- Effects of methotrexate on the liver in psoriasis. (1974) (49)
- Studies on uterine collagenase in tissue culture. I. Relationship of enzyme production to collagen metabolism. (1971) (49)
- Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with noncollagenous substrates. (1980) (49)
- Sulfhydryl groups in the skin of the mouse and guinea pig. (1953) (48)
- Comparison of cleavage site specificity of gelatinases A and B using collagenous peptides. (1996) (48)
- The structure of the integument of the sea cucumber, Thyone briareus (1970) (48)
- Scleromyxoedema: treatment of cutaneous and systemic manifestations with high‐dose intravenous immunoglobulin (2003) (47)
- Collagenase in Sjögren's syndrome. (1994) (44)
- Cleavage specificity of type IV collagenase (gelatinase) from human skin. Use of synthetic peptides as model substrates. (1989) (43)
- Preparation of three vertebrate collagenases in pure form. (1971) (40)
- Basement membrane zone remodeling during appendageal development in human fetal skin. The absence of type VII collagen is associated with gelatinase-A (MMP2) activity. (2000) (40)
- Circumscribed acral hypokeratosis. (2007) (39)
- Hormonal interactions in mammalian collagenase regulation. Comparative studies in human skin and rat uterus. (1980) (39)
- Characterization of a collagenase from rat skin. (1972) (39)
- Cutaneous protothecosis. Successful treatment with amphotericin B. (1976) (39)
- Regulation of vertebrate collagenase activity in vivo and in vitro. (1972) (38)
- Pseudouridine metabolism. II. Urinary excretion in gout, psoriasis, leukemia, and heterozygous oroticaciduria. (1962) (37)
- Studies on purified rheumatoid synovial collagenase in vitro and in vivo. (1971) (37)
- Verrucous lupus erythematosus: ultrastructural studies on a distinct variant of chronic discoid lupus erythematosus. (1983) (37)
- Extracellular matrix metalloproteinases in tumor invasion and metastasis. (1991) (36)
- or: Characterization and (2016) (36)
- Cutaneous wound healing in the sea cucumber, Thyone briareus (1973) (36)
- Role of Mesenchymal Collagenase in the Loosening of Total Hip Prosthesis (1993) (35)
- Structural organization of the stratum corneum in certain scaling disorders of the skin. (1971) (35)
- The induction of collagenase by thyroxine in resorbing tadpole tailfin in vitro. (1975) (35)
- Generalized dominant epidermolysis bullosa simplex: decreased activity of a gelatinolytic protease in cultured fibroblasts as a phenotypic marker. (1983) (33)
- Differentiation of a human leukemia cell line and expression of collagenase inhibitor. (1985) (32)
- Focal dermal hypoplasia: abnormal growth characteristics of skin fibroblasts in culture. (1980) (29)
- Pseudouridine metabolism. I. Isolation and the effect of diet on urinary excretion. (1962) (29)
- Activation of gelatinase A (72-kDa type IV collagenase) induced by monensin in normal human fibroblasts. (1997) (29)
- Glucocorticoid modulation of collagenase expression in human skin fibroblast cultures. Evidence for pre-translational inhibition. (1985) (28)
- [53] Collagenolytic protease from fiddler crab (Uca pugilator) (1981) (23)
- The metabolism of ring-labeled orotic acid in man. (1962) (23)
- Activation of extracellular matrix metalloproteases by proteases and organomercurials. (1992) (22)
- The stoichiometric activation of human skin fibroblast pro-collagenase by factors present in human skin and rat uterus. (1981) (22)
- Native type I collagen is not a substrate for MMP2 (gelatinase A) (1999) (21)
- Cutaneous lesions of lymphomatoid granulomatosis. (1986) (21)
- Verrucous lesion in patients with discoid lupus erythematosus. Clinical, histopathological and immunofluorescence studies. (1978) (20)
- Primary structure and function of stromelysin/transin in cartilage matrix turnover. (1992) (20)
- Protein tyrosine phosphorylation in signalling pathways leading to the activation of gelatinase A: activation of gelatinase A by treatment with the protein tyrosine phosphatase inhibitor sodium orthovanadate. (1998) (20)
- Enhanced cell-free translation of human skin collagenase in recessive dystrophic epidermolysis bullosa. (1982) (20)
- Methotrexate Therapy in Psoriatic Arthritis (2017) (18)
- Human skin fibroblasts in culture: procollagen synthesis in the presence of sera from normal human subjects and from patients with dermal fibroses. (1981) (18)
- Human skin collagenase: assignment of the structural gene to chromosome 11 in both normal and recessive dystrophic epidermolysis bullosa cells using human-mouse somatic cell hybrids. (1983) (18)
- Interstitial collagenase and the ED-B oncofetal domain of fibronectin are markers of angiogenesis in human skin tumors. (1998) (17)
- Purification of gelatin-specific neutral protease from human skin by conventional and high-performance liquid chromatography. (1985) (17)
- Studies on urinary γ-globulins in patients with rheumatoid arthritis (1966) (17)
- The induction of collagenase and acid phosphatase by thyroxine in resorbing tadpole gills in vitro (1979) (14)
- Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors. (1992) (14)
- Eriochrome black T inhibition of human skin collagenase, but not gelatinase, using both protein and synthetic substrates. (1987) (13)
- Behavior of epidermolysis bullosa fibroblasts in a hydrated collagen lattice. (1987) (13)
- Studies on the activation energy and deuterium isotope effect of human skin collagenase on homologous collagen substrates. (1983) (11)
- The Tinctorial Behaviour of Human Mast Cells (1954) (11)
- Pseudouridine (5-ribosyl uracil) excretion in psoriasis. (1962) (10)
- A component of normal human serum which enhances the activity of vertebrate collagenases. (1978) (9)
- Chromomycosis. Successful treatment with 5-fluorocytosine. (1979) (9)
- Erythromelalgia of the ears: an unusual variant and response to therapy. (2008) (7)
- Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with collagenous substrates. (1982) (5)
- Regulation of gelatinase in human skin organ cultures by glucocorticoids. (1983) (4)
- Cutaneous angiosarcoma of the knee: a case report and review of the literature. (2009) (4)
- Regulation of gelatinase in human skin organ cultures by glucocorticoids. (1983) (3)
- Keratinocyte‐ and Tumor‐Derived Inducers of Collagenase a (1988) (3)
- Biochemical changes in certain genodermatoses. (1985) (3)
- Collagenase in human cutaneous diseases: fidelity of expression in fibroblast cultures. (1983) (3)
- Solid-phase radioimmunoassay of rat skin collagenase. Comparative studies and in vivo measurement of the enzyme. (1974) (3)
- [47] Vertebrate collagenases (1974) (2)
- Serum and Urinary Gamma Globulins in Rheumatoid Arthritis (1966) (2)
- Mycosis Fungoides: Natural History and Relationship to Other Malignant Lymphomas. (1962) (1)
- Relationship of antitrypsin deficiency to the pathogenesis of emphysema. (1969) (1)
- Proceedings and Transactions (1987) (0)
- Human fibroblast collagenase : Glycosylation and tissue-specific evels of enzyme synthesis ( phorbol diester / gene expression / metallo-endoprotease inhibitor / collagen degradation ) (2003) (0)
- The structure and mechanical properties of the dermis of tight-skin (tsk) mutant mice. Abstr. (1977) (0)
- SERUM URATE VALUES CORRELATED WITH THE ESTIMATED PERCENTAGE OF SKIN INVOLVED WITH PSORIASIS (0)
- Sweet Syndrome With Pulmonary Involvement Preceding the Development of Myelodysplastic Syndrome. (2022) (0)
- Chromomycosis (1979) (0)
- Affinity chromatography of vertebrate collagenases. (1974) (0)
- The Effects of Strontium and Calcium on Mammalian Collagenases (1981) (0)
- Evidence for Increased Collagenase as a Genetic Characterist ic in Cell Culture* BY EUGENE A. BAUER~ AND ARTHUR (2003) (0)
- Letter (1990) (0)
- Collagenase in S jogren ' s syndrome (2004) (0)
- The cutaneous effects of glucocorticoids. (1984) (0)
- SID 2015 Contributors. (2015) (0)
- Physician-scientist as a mentor. (2011) (0)
- Searching for a major locus for male pattern baldness (MPB) (1994) (0)
- Disorders Associated with Collagen Biosynthesis (2021) (0)
- SKIN COLLAGENASE QUANTITATIVE DETERMINATION OF IN VIVO AND IN VITRO HUMAN Radioimmunoassay of Human Collagenase : SPECIFICITY OF THE ASSAY AND (2003) (0)
- FHBROBLAST COLLAGENASE ENZYME (2017) (0)
- Color Atlas of Rheumatology (Book) (1975) (0)
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