Abraham A. Brouwer
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Abraham A. Brouwerchemistry Degrees
Chemistry
#5013
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#6115
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Organic Chemistry
#838
World Rank
#939
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Chemistry
Abraham A. Brouwer's Degrees
- PhD Chemistry University of Amsterdam
- Masters Chemistry University of Amsterdam
- Bachelors Chemistry University of Amsterdam
Why Is Abraham A. Brouwer Influential?
(Suggest an Edit or Addition)Abraham A. Brouwer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. (2000) (891)
- In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds. (2001) (744)
- In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. (2006) (686)
- Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health (1998) (622)
- Effects of Dioxins and Polychlorinated Biphenyls on Thyroid Hormone Status of Pregnant Women and Their Infants (1994) (499)
- Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. (1999) (441)
- Polychlorinated biphenyl (PCB)-contaminated fish induces vitamin A and thyroid hormone deficiency in the common seal (Phoca vitulina) (1989) (382)
- Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1996) (377)
- Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. (2000) (366)
- Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water. (1996) (358)
- Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs. (1999) (340)
- Are brominated flame retardants endocrine disruptors? (2003) (328)
- Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. (2004) (299)
- Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants. (1995) (281)
- Activation of the Ah receptor by tryptophan and tryptophan metabolites. (1998) (278)
- Binding of a metabolite of 3,4,3',4'-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin. (1986) (273)
- Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays. (2008) (253)
- Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons. (1996) (249)
- Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254). (1996) (243)
- Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. (2002) (243)
- Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). (2008) (227)
- Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. (2002) (217)
- Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. (1992) (205)
- Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats. (1993) (190)
- Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays. (2002) (189)
- Screening methods for thyroid hormone disruptors. (1999) (181)
- Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities. (2006) (179)
- Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3'4,4'-hexachlorobiphenyl. (1995) (176)
- Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. (2002) (173)
- In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated aromatic hydrocarbons. (1998) (158)
- The risk of endometriosis and exposure to dioxins and polychlorinated biphenyls: a case-control study of infertile women. (2001) (154)
- Identification of estrogenic compounds in fish bile using bioassay-directed fractionation. (2004) (150)
- Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish. (2008) (149)
- Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. (1993) (146)
- Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive. (2018) (140)
- Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. (2008) (134)
- Thyroxine and 3,3',5-triiodothyronine are glucuronidated in rat liver by different uridine diphosphate-glucuronyltransferases. (1991) (131)
- Binding of a 3,3', 4,4'-tetrachlorobiphenyl (CB-77) metabolite to fetal transthyretin and effects on fetal thyroid hormone levels in mice. (1996) (130)
- Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. (2003) (123)
- Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment. (1995) (121)
- Chromatographic analysis of endogenous retinoids in tissues and serum. (2003) (120)
- Report of the WHO working group on the assessment of health risks for human infants from exposure to PCDDs, PCDFs and PCBs. (1998) (114)
- Biochemical and toxic effects of polychlorinated biphenyls (PCBs), dibenzo-P-dioxins (PCDDs) and dibenzofurans (PCDFs) in the cormorant (phalacrocorax carbo) after in ovo exposure (1994) (110)
- Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption (2004) (108)
- Role of biotransformation in PCB-induced alterations in vitamin A and thyroid hormone metabolism in laboratory and wildlife species. (1991) (102)
- A Novel in Vivo Bioassay for (Xeno-)estrogens Using Transgenic Zebrafish (2000) (99)
- Effects of PCDDs, PCDFs and PCBs in common tern (sterna hirundo) breeding in estuarine and coastal colonies in the netherlands and belgium (1995) (97)
- Validation and use of the CALUX-bioassay for the determination of dioxins and PCBs in bovine milk. (1998) (95)
- Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls. (1998) (94)
- In vitro metabolism of 3,3',4,4'-tetrachlorobiphenyl in relation to ethoxyresorufin-O-deethylase activity in liver microsomes of some wildlife species and rat. (1994) (93)
- Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER‐CALUX reporter gene assay (2002) (93)
- Effects of Polychlorinated Biphenyls (PCBs) and Dioxins on Growth and Development (1994) (93)
- Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats. (2004) (92)
- Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. (2013) (89)
- PAH-CALUX, an optimized bioassay for AhR-mediated hazard identification of polycyclic aromatic hydrocarbons (PAHs) as individual compounds and in complex mixtures. (2013) (86)
- In vitro characterization of the effectiveness of enhanced sewage treatment processes to eliminate endocrine activity of hospital effluents. (2013) (86)
- Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses. (2006) (85)
- Identification of 4-Hydroxyheptachlorostyrene in Polar Bear Plasma and Its Binding Affinity to Transthyretin: A Metabolite of Octachlorostyrene? (2000) (82)
- Study on the mechanism of interference of 3,4,3',4'-tetrachlorobiphenyl with the plasma retinol-binding proteins in rodents. (1988) (80)
- Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition. (1998) (77)
- SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part I–model design and effect‐based trigger values (2017) (76)
- Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls. (1989) (75)
- Extrathyroidal effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone turnover in male Sprague-Dawley rats. (1997) (75)
- The calux (chemical‐activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma (1997) (75)
- Structure of human transthyretin complexed with bromophenols: a new mode of binding. (2000) (72)
- Detection of anabolic androgenic steroid abuse in doping control using mammalian reporter gene bioassays. (2009) (71)
- In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems. (2002) (71)
- Marked alterations in retinoid homeostasis of Sprague-Dawley rats induced by a single i.p. dose of 10 micrograms/kg of 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1989) (71)
- Environmental Occurrence, Analysis and Toxicology of Toxaphene Compounds (1999) (69)
- Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells. (2002) (69)
- Long-term alterations in regional brain serotonin metabolism following maternal polychlorinated biphenyl exposure in the rat. (1996) (65)
- Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys. (1988) (64)
- Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats. (2004) (64)
- Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines. (1995) (62)
- Health risks to infants from exposure to PCBs, PCDDs and PCDFs (2000) (61)
- Persistent alterations in regional brain glial fibrillary acidic protein and synaptophysin levels following pre- and postnatal polychlorinated biphenyl exposure. (1996) (57)
- Agaricus bisporus and its by-products as a source of valuable extracts and bioactive compounds. (2019) (57)
- In vitro inhibition of thyroid hormone sulfation by polychlorobiphenylols: isozyme specificity and inhibition kinetics. (1998) (56)
- Effects of polyhalogenated aromatic hydrocarbons (PHAHs) on biochemical parameters in chicks of the common tern (Sterna hirundo) (1994) (56)
- Impaired cellular immune response in rats exposed perinatally to Baltic Sea herring oil or 2,3,7,8-TCDD (1997) (53)
- Biochemical and physiological approaches in ecotoxicology. (1990) (53)
- Comparison of chemical-activated luciferase gene expression bioassay and gas chromatography for PCB determination in human serum and follicular fluid. (2000) (52)
- Interference between Progesterone and Dioxin Signal Transduction Pathways (1998) (51)
- Metabolism and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl in pregnant and fetal rats. (1995) (51)
- Endocrine effects of polycyclic musks: do we smell a rat? (2008) (51)
- Environmental occurrence, analysis, and toxicology of toxaphene compounds. (1999) (50)
- The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study. (1993) (49)
- Time and dose responses of the reduction in retinoid concentrations in C57BL/Rij and DBA/2 mice induced by 3,4,3',4'-tetrachlorobiphenyl. (1985) (49)
- Effects of subchronic exposure to complex mixtures of dioxin-like and non-dioxin-like polyhalogenated aromatic compounds on thyroid hormone and vitamin A levels in female Sprague-Dawley rats. (2001) (49)
- Biomonitoring of estrogenic exposure and identification of responsible compounds in bream from Dutch surface waters (2007) (47)
- Early and differential decrease in natural retinoid levels in C57BL/Rij and DBA/2 mice by 3,4,3',4'-tetrachlorobiphenyl. (1984) (46)
- Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor. (2007) (46)
- Sample preparation method for the ER-CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts. (2007) (46)
- Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development. (2010) (44)
- Effects of pentachlorophenol and hydroxylated polychlorinated biphenyls on thyroid hormone conjugation in a rat and a human hepatoma cell line. (1999) (42)
- Contribution of planar (0-1 ortho) and nonplanar (2-4 ortho) fractions of Aroclor 1260 to the induction of altered hepatic foci in female Sprague-Dawley rats. (2000) (42)
- Interaction of polybrominated biphenyls ether metabolites (PBDE-OH) with human transthyretin in vitro. (1998) (41)
- Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs. (2010) (41)
- Effects of iron-ore mining and processing on metal bioavailability in a tropical coastal lagoon (2008) (41)
- Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like PCBs in mouse hepatoma cells (Hepa1c1c7): involvement of the Ah receptor. (1994) (40)
- Host resistance to rat cytomegalovirus (RCMV) and immune function in adult PVG rats fed herring from the contaminated Baltic Sea (1996) (40)
- Distribution of the flame retardant tetrabromobisphenol A in pregnant and fetal rats and effect on thyroid hormone homeostasis (1999) (39)
- Polybrommated diphenyl ethers (PCDs) as Ah-receptor agonists and antagonists. (1998) (38)
- Chronic and reproductive toxicity of a mixture of 15 methylsulfonyl‐polychlorinated biphenyls and 3‐methylsulfonyl‐2,2‐bis‐(4‐chlorophenyl)‐1,1‐dichloroethene in mink (Mustela vison) (1999) (38)
- Low hepatic 7-ethoxyresorufin-O-deethylase (EROD) activity and minor alterations in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50. (1996) (38)
- Toxic and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl (CB-77) and clophen A50 on eider duckling (Somateria mollissima) in a semi-field experiment. (1994) (37)
- Comprehensive evaluation of dioxins and dioxin-like compounds in surface soils and river sediments from e-waste-processing sites in a village in northern Vietnam: Heading towards the environmentally sound management of e-waste (2016) (37)
- Fetal, neonatal, and long-term alterations in hepatic retinoid levels following maternal polychlorinated biphenyl exposure in rats. (1995) (36)
- Alterations in plasma and hepatic retinoid levels in flounder (Platichthys flesus) after chronic exposure to contaminated harbour sludge in a mesocosm study (1998) (35)
- A Panel of Quantitative Calux® Reporter Gene Assays for Reliable High‐Throughput Toxicity Screening of Chemicals and Complex Mixtures (2013) (35)
- Ah-receptor mediated luciferase expression: a tool for monitoring dioxin-like toxicity. (1993) (34)
- Interference of polychlorinated biphenyls in thyroid hormone metabolism: possible neurotoxic consequences in fetal and neonatal rats. (1992) (33)
- High induction of cytochrome p4501a activity without changes in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (1997) (32)
- Identification of major dioxin-like compounds and androgen receptor antagonist in acid-treated tissue extracts of high trophic-level animals. (2011) (32)
- Biological validation of a sample preparation method for ER-CALUX bioanalysis of estrogenic activity in sediment using mixtures of xeno-estrogens. (2006) (31)
- Application of the chemical-activated luciferase expression (CALUX) bioassays for quantification of dioxin-like compounds in small samples of human milk and blood plasma. (1996) (31)
- Biotransfiormation and Toxicity of Halogenated Benzenes (1994) (30)
- Interactive effects of 2,2'-4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone, vitamin A, and vitamin K metabolism in the rat. (1992) (30)
- Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms. (2005) (30)
- Steroid hormonal bioactivities, culprit natural and synthetic hormones and other emerging contaminants in waste water measured using bioassays and UPLC-tQ-MS. (2018) (30)
- Screening white-rot fungi for bioremediation potential of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2019) (29)
- Antimicrobial activity and carbohydrate metabolism in the bacterial metagenome of the soil-living invertebrate Folsomia candida (2019) (28)
- Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis. (2014) (27)
- SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part II–field feasibility survey (2017) (27)
- Induction of altered hepatic foci by a mixture of dioxin-like compounds with and without 2,2',4,4',5,5'-hexachlorobiphenyl in female Sprague-Dawley rats. (1999) (26)
- The use of biochemical parameters in comparative toxicological studies with the cormorant () in the Netherlands (1992) (26)
- Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan. (2015) (26)
- Thyroxine binding to transthyretin Met 119 (1997) (26)
- Early decrease in retinoid levels in mice after exposure to low doses of polychlorinated biphenyls (1983) (25)
- Bio/chemical Analysis of Dioxin-like Compounds in Sediment Samples from Osaka Bay, Japan (2005) (25)
- Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity. (2005) (24)
- Occurrence of endophytic bacteria in Vietnamese Robusta coffee roots and their effects on plant parasitic nematodes (2019) (23)
- Comparison of dioxin and PCB concentrations in human breast milk samples from Hong Kong and the Netherlands (2003) (23)
- Maternal diet and dioxin-like activity, bulky DNA adducts and micronuclei in mother-newborns. (2012) (23)
- Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: relevant exposure measures for endocrine disruptors in epidemiologic studies? (2011) (22)
- Production of novel recombinant cell line bioassay systems for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1993) (22)
- The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays (2018) (22)
- Evolutionary ecology of beta‐lactam gene clusters in animals (2017) (22)
- beta-Naphthoflavone- and self-induced metabolism of 3,3',4,4'-tetrachlorobiphenyl in hepatic microsomes of the male, pregnant female and foetal rat. (1995) (21)
- Alterations in retinoid concentrations in several extrahepatic organs of rats by 3,4,3',4'-tetrachlorobiphenyl. (1988) (20)
- Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. (2018) (20)
- Application of CALUX bioassay system for the detection of dioxin-like chemicals (Ah receptor ligands) in whole serum samples and in extracts from commercial and consumer products. (1996) (20)
- Statement From the Work Session On Environmental Endocrine-Disrupting Chemicals: Neural, Endocrine, and Behavioral Effects (1998) (19)
- Newborn infants diagnosed as neurologically abnormal with relation to PCB and dioxin exposure and their thyroid-hormone status. (1997) (19)
- Determination of the endocrine disrupting potency of hydroxylated PCB's and flame retardants with in vitro bioassays (2002) (18)
- Enzyme induction and alterations in thyroid hormone, vitamin A and K levels by TCDD in neonatal and maternal rats (1990) (17)
- Application of the CALUX (chemical activated luciferase gene expression) assay for measuring TCDD-equivalents in sediment, pore water and blood plasma samples. (1996) (16)
- Subchronic toxicity and reproduction effects of tri-n-butyltin oxide in Japanese quail (1992) (16)
- Formation of polybrominated dibenzofurans (PBDFs) after heating of a salmon sample spiked with decabromodiphenyl ether (BDE-209) (2015) (16)
- Patterns of variability of retinol levels in a harbour porpoise population from an unpolluted environment (1999) (15)
- Screening for PCDD/Fs and dl-PCBs in local and imported food and feed products available across the State of Kuwait and assessment of dietary intake. (2014) (15)
- 3,4,3',4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. I. Serum and Hepatic Retinoid Reduction and Morphologic Changes (1989) (15)
- 3,4,3',4'-Tetrachlorobiphenyl distribution and induced effects in the rat adrenal gland. Localization in the zona fasciculata. (1990) (15)
- Inhibition of intercellular communication and induction of ethoxyresorufin-O-deethylase activity by polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans in mouse hepa1c1c7 cells. (1996) (14)
- Effects on thyroid hormone metabolism and depletion of lung vitamin A in rats by airborne particulate matter. (1993) (14)
- Dioxin type and mixed type induction of the cytochrome P-450 system of common eider ducklings (Somateria mollissima) by PCBs: with indications for biotransformation. (1995) (14)
- Harmonised quality criteria for chemical and biossays analyses of PCDDs/PCDFs in feed and food part 2: General considerations, biossay methods (2001) (14)
- Toxicokinetics of an environmentally relevant mixture of dioxin-like PHAHs with or without a non-dioxin-like PCB in a semi-chronic exposure study in female Sprague Dawley rats. (1998) (13)
- Determination of dioxin- and estrogen-like activity in sediment extracts using in vitro CALUX assays. (1996) (12)
- DR- and ER-CALUX assays as tools to direct toxicity identification and evaluation of endocrine disrupting chemicals (2002) (12)
- Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachlorobiphenyl. (1993) (12)
- Effects of outdoor and indoor airborne particulate matter on thyroid hormone and vitamin A metabolism. (1994) (11)
- CAFLUX, a simplified version of the CALUX assay for Ah receptor (ant)agonist, based on enhanced green fluorescent protein (EGFP) reporter gene expression. (1998) (11)
- In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins (2021) (11)
- Toxicological risks to humans of toxaphene residues in fish (2012) (11)
- Assessing Indoor Dust Interference with Human Nuclear Hormone Receptors in Cell-Based Luciferase Reporter Assays (2021) (11)
- DR-CALUX®- and EROD-TEF values for dioxin-like compounds (PXBs/PXDDs/Fs; X=Br, Cl) and others (e.g. PAHs) (2001) (11)
- Developing potency factors for thyroid hormone disruption by PFASs using TTR-TRβ CALUX® bioassay and assessment of PFASs mixtures in technical products. (2021) (11)
- Dr‐Calux®: A High‐Throughput Screening Assay for the Detection of Dioxin and Dioxin‐Like Compounds in Food and Feed. (2013) (10)
- Evaluation of a panel of in vitro methods for assessing thyroid receptor β and transthyretin transporter disrupting activities. (2020) (10)
- Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays. (2020) (10)
- Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin biodegradation by extracellular lignin-modifying enzymes from ligninolytic fungus. (2021) (9)
- In vitro screening of the endocrine disrupting potency of brominated flame retardants and their metabolites (2004) (9)
- Subchronic toxicity of Baltic herring oil and its fractions in the rat II: Clinical observations and toxicological parameters. (2002) (8)
- Structure dependent multiple interactions of polyhalogeneted aromatic hydrocarbons with the thyroid hormone system. (1998) (8)
- Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes. (2019) (8)
- Antagonistic effects on mono- and di-ortho-substituted polychlorinated biphenyls in the ethoxy-resorufin-o-diethylase activity and the luciferase reporter gene assay in vitro. (1998) (8)
- Species-specific differences in Ah receptor ligand binding and transcriptional activation: implications for bioassays for the detection of dioxin-like chemicals. (1995) (8)
- Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays (2017) (8)
- In vitro and in vivo tumor promoting potency of technical toxaphene, uv-irradiated toxaphene, and biotransformed toxaphene (2000) (8)
- 3,4,3,4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. II. Electron Microscopic Autoradiographic Localization of H-TCB (1989) (8)
- Genome annotation and antimicrobial properties of Bacillus toyonensis VU‐DES13, isolated from the Folsomia candida gut (2019) (8)
- Hepatic retinoid levels in seven fish species (teleosts) from a tropical coastal lagoon receiving effluents from iron‐ore mining and processing (2012) (7)
- Effect of Aroclor 1254 on thyroid hormone sulfation in fetal rats. (1998) (7)
- The effect of 3,3′,4,4′-tetrachlorobiphenyl and clophen A50 on the hepatic monooxygenase system of Eider Ducklings (Somateria mollissima) with indications for structure-related biotransformation of CB congeners (1992) (7)
- Prenatal exposure of rats to hydroxylated PCBs and some brominated flame retardants (2006) (7)
- Versicolorin A enhances the genotoxicity of Aflatoxin B1 in human liver cells by inducing the transactivation of the Ah-Receptor. (2021) (7)
- Synergistic Effect of 2,2 prime ,4,4 prime ,5,5 prime -Hexachlorobiphenyl and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Hepatic Porphyrin Levels in the Rat (1996) (7)
- Cross-validation study of the DR-CALUX®-bioassay Comparison to Micro-EROD bioassay and chemical analyses (2001) (6)
- Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort. (2020) (6)
- Effects of retinoic acid on the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced differentiation of in vitro cultured human keratinocytes. (1994) (6)
- Development of improved DR-CALUX bioassay for sensitive measurement of aryl hydrocarbon receptor activating compounds (2002) (6)
- CONTEMPORARY RELEVANCE OF DIOXIN AND DIOXIN LIKE COMPOUND CONTAMINATIONS IN RESIDUES FROM RECYCLING OF HCH WASTE (2006) (6)
- Effects of prenatal exposure to hydroxylated PCB metabolites and some brominated flame retardants on the development of rats (2004) (6)
- Observation of an extremely high dioxin level in a human serum sample from ukraine by Dr Calux®, which was confirmed to be 2,3,7,8-tetrachlorodibenzo-p-dioxin by gc-hrms (2005) (6)
- Interactive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and retinoids on proliferation and differentiation in cultured human keratinocytes: quantification of cross-linked envelope formation (2009) (6)
- Evaluation of tumour promoting potency of fish borne toxaphene residues, as compared to technical toxaphene and UV-irradiated toxaphene. (2008) (5)
- Effect-based detection of synthetic glucocorticoids in bovine urine (2015) (5)
- Post-mortem stability of blubber DLCs, PCB and tDDT in by-caught harbour porpoises (Phocoena phocoena). (2007) (5)
- A low volume method for the analysis of dioxins and dioxin-like compounds in serum and whole blood using BDS¿ Dr Calux® Bioassay (2004) (5)
- Effects of PCBs and dioxins during pregnancy and breast feeding on growth and development of newborn infants. A study design and preliminary results. (1992) (4)
- Correlating Biodegradation Kinetics of 2,4-Dichlorophenoxyacetic Acid (2,4-D) and 2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T) to the Dynamics of Microbial Communities Originating From Soil in Vietnam Contaminated With Herbicides (2021) (4)
- Biodegradation of Fipronil: Transformation Products, Microbial Characterisation and Toxicity Assessment (2021) (4)
- Analysis of PCB congeners (by GC-ECD) and dioxin-like toxic equivalence (by CALUX assay) in females with endometriosis and other fertility problems (1999) (4)
- Peregrine falcon egg pollutants (2016) (4)
- Effects of hydroxy-dioxins on thyroid hormone binding to transthyretin and thyroid hormone type 1 deiodinase activity in vitro and in vivo. (1993) (4)
- Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DRhuman CALUX reporter gene assay. (2021) (4)
- Perinatal alterations of thyroid homeostasis and long-term neurochemical alterations in rats following maternal Aroclor 1254 exposure. (1994) (4)
- Prenatal Aroclor 1254 exposure selectively alters regional glial fibrillary acidic protein levels in the rat brain. (1993) (4)
- Anti-androgenic compounds in breast milk and cryptorchidism among Norwegian boys in the HUMIS birth cohort. (2021) (4)
- Hydroxylated PCBs (OH‐PCBs) as potential endocrine disrupters ‐ exposures and toxic effects (2001) (4)
- Assessment of (anti)oestrogenic compounds using a stably transfected luciferase reporter gene assay in the human T47-D breast cancer cell line. (1998) (4)
- A risk-based field and laboratory approach to assess endocrine disruptions in wildlife. (1998) (4)
- Flame retardants, polychlorinated biphenyls and insecticides in pregnant women in the northern part of the Netherlands (2004) (4)
- Survey of toxaphene concentrations in fish from European waters (2000) (3)
- 668 Effects of 4-OH-CB 107 and 4-OH-CB 187 on development and endocrine status of the rat (2003) (3)
- Antagonistic effects of diortho PCBs (PCB 52 and 128) on Ah receptor-mediated induction of luciferase activity by 3,3',4,4'-tetrachlorobiphenyl (PCB 77) in mouse Hepa-1c1c7 cells. (1993) (3)
- Macrophages influence gap junctional intercellular communication between smooth muscle cells in a co-culture model. (1998) (3)
- Modulating effects of thyroid state on the induction of biotransformation enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1998) (3)
- Thyroid hormone binding proteins as targets for hydroxylated PCB, PCDD and PCDF metabolites; an overview. (1994) (3)
- PCB destruction by catalytic hydrodechlorination (CHD) and t-BuOK method: combinatorial bio/chemical analysis (2001) (3)
- Peregrine falcon egg pollutants: Mirror Stockholm POPs list including methylmercury (2016) (3)
- Identification of PPAR-activating compounds in herbal and edible plants and fungi from Vietnam (2019) (3)
- Calux® reporter cell lines as sensitive bioassay for monitoring biological activity of various classes of steroid hormones revert the repressive effect of TCDD on the estrogen receptor (2003) (3)
- Degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) by fungi originating from Vietnam (2022) (3)
- Species and Metabolic Pathways Involved in Bioremediation of Vietnamese Soil From Bien Hoa Airbase Contaminated With Herbicides (2021) (2)
- Elucidating fungal Rigidoporus species FMD21 lignin-modifying enzyme genes and 2,3,7,8-tetrachlorodibenzo-p-dioxin degradation by laccase isozymes. (2021) (2)
- Effect on retinoid homeostasis in the flounder (Platichtys flesus) following chronic exposure to contaminated harbour dredge spoil from Rotterdam harbour. (1996) (2)
- Low hepatic ethyoxyresorufin-o-deethylase (EROC) induction with no detectable cytosolic Ah-receptor levels in Flounder (Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50. (1993) (2)
- Project proposal. Evaluating human health risk from low-dose and long-term exposure to polychlorinated biphenyls. (2000) (2)
- Altered thyroxine binding to amyloidogenic and non-amyloidogenic transthyretin variants: TTR Met 119 and TTR Pro 55 (1996) (2)
- Validation of extraction, clean-up and Dr Calux® bioanalysis.Part I: Feedingstuff (2004) (2)
- Developments in analysis and toxicology of toxaphene compounds. (1998) (2)
- GR CALUX assay detects synthetic glucocorticoids in calf urine: a validation study (2019) (2)
- Glucocorticoid mediated expression of dioxin target genes in rat H4IIe cells but not in human HepG2 and T47D cells (2006) (2)
- Induction of biotransformation enzymes by polyhalogenated aromatic hydrocarbons (PHAHs): potential impact on animal physiology and health (1999) (2)
- Effect-directed analysis and chemical identification of agonists of peroxisome proliferator-activated receptors in white button mushroom. (2020) (1)
- Investigation of the soil nematode community composition in a monoculture Robusta coffee plantation in Dak Lak, Vietnam (2021) (1)
- Evaluation of potential bioaccumulative compounds exerting endocrine-disrupting activities in wild animals using vitro bioassays and chemical fractionation (2010) (1)
- Tumour promotion induction by complex mixtures of 2-4 and 0-1 ortho polychlorinated biphenyls in female sprague Dawley rats. (1998) (1)
- Systematic surveillance for management of Dioxin contamination risks in the food chain: Germany and related cases (2012) (1)
- Binding of several hydroxychlorobiphenyls to the thyroid hormone transport protein, transthyretin. (1993) (1)
- Endocrine activities of phthalate alternatives; assessing the safety profile of furan dicarboxylic acid esters using a panel of human cell based reporter gene assays (2020) (1)
- Applications of in Vitro Screening Tools to Support Risk Assessment of Brominated Flame Retardants (2006) (1)
- Correlating biodegradation kinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the dynamics of microbial communities originating from soil in Vietnam contaminated with herbicides and dioxins (2022) (1)
- Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings. (2022) (1)
- In vitro metabolism of 3,4,3',4,4'-tetrachlorobiphenyl by microsomes of wildlife species compared to the rat. (1993) (1)
- Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): possible role of the Ah-receptor. (1993) (1)
- Estrogenic mixture effects in the ER-CALUX® assay used for the biological validation of an extraction and clean up method for sediments (2005) (0)
- Responses of mixtures of polyhalogenated aromatic compounds or single compounds in the CALUX-assay a novel species-specific bioassay for Ah-receptor active compounds (1995) (0)
- Phenolic organohalogen-thyroid hormone disruptors: mechanisms and neurochemical consequences for animal offspring. (1998) (0)
- Non-additive inductions of altered hepatic foci in female sprague Dawley rats by a mixture of dioxin-like compounds. (1996) (0)
- A genomics approach to identifying mechanisms of developmental toxicity in zebrafish (2008) (0)
- Molecular characterization of the Ah-receptor pathway in flounder (Platichtys flesus). (1998) (0)
- Screening the hormonal activity of endocrine disruptors chemicals in food contact materials with Reporter Gene Assays: A first screening step (2016) (0)
- Extraction and bioanalysis of arylhydrocarbon- and estrogen- receptor active compounds (1997) (0)
- Vitamin A reduction in Eider ducklings (Somateria mollissima) exposed to polychlorinated biphenyls (CB-77 and Clophen A50). (1993) (0)
- Introduction of a linear 2,3,7,8-TCDD curve-fit as a means to Improve performance characteristics of the (2005) (0)
- Application of in vitro and in vivo reporter gene assays for assessing (mixtures of) estrogenic substances (2001) (0)
- Paleotoxicity of petrogenic and pyrogenic hydrocarbon mixtures in sediment cores from the Athabasca oil sands region, Alberta (Canada). (2021) (0)
- Identification and risk assessment of endocrine disrupting compounds. Part I: toxicity profile measurements in Dutch aquatic sediments (2001) (0)
- Hagenmaier drum - fly ash Dechlorination/ hydrogenation process: Combinatorial bio/chemical analysis (2001) (0)
- 115 EFFECTS OF DIOXINS AND POLYCHLORINATED BIPHENYLS ON THYROID HORMONE STATUS OF PREGNANT WOMEN AND THEIR INFANTS (1994) (0)
- Antagonistic effects of retinoic acid on the 2,3,7,8-tetrachlordibenzo-p-dioxin induced differentiation of in vitro cultured human keratinocytes. (1993) (0)
- Degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) by fungi originating from Vietnam (2022) (0)
- Identification of dioxin-like and estrogenic compounds in sediment using Calux® assay-directed fractionation combined with two-dimensional comprehensive GCxGC-TOF MS (2004) (0)
- The first BIO-survey on synthetic glucocorticoid abuse in food producing bovines (2015) (0)
- In vitro genotoxicity and tumor promoting potency of technical toxaphene, uv-irridiated toxaphene, and weathered toxaphene (2000) (0)
- Toxicological response in rats fed Baltic Sea Herring oil and its fractions for 13 weeks. (1998) (0)
- Development of Calux bioassay-based systems as instruments to detect hormones and contaminants (2006) (0)
- Bioanalytical Detection of Steroid Abuse in Sports Based on the Androgenic Activity Measurement (2021) (0)
- Development of a toxicity identification and evaluation method for estrogenic chemicals in fish bile (2004) (0)
- A Functional Carbohydrate Degrading Enzyme Potentially Acquired by Horizontal Gene Transfer in the Genome of the Soil Invertebrate Folsomia candida (2022) (0)
- Measurement of (anti-)oestrogenic potency in complex mixtures using a novel stably transfected luciferase reporter gene assay in the human T47D breast cancer cell (2000) (0)
- Improving infant food safety by avoiding hazards of chemical mixture effects using novel integrated methods based on bioassays and analytical chemistry (2022) (0)
- Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays (2016) (0)
- Geochemistry, bioavailability, bioaccumulation and toxicology of trace metals related to iron ore mining - Case study: Samarco Mineraçao (2005) (0)
- Inter-laboratory Calibration Study for Dioxins in Food/Feedstuff using DR-CALUX Assay (2007) (0)
- Synthetic glucocorticoids in bovine urine: From targeted to untargeted detection (2013) (0)
- Expression profiling of zebrafish embryonic fibroblast cells exposed to 6-OH-BDE 47 (2006) (0)
- In vivo promoting potency of technical toxaphene, uv-irridiated toxaphene, and weathered toxaphene (2000) (0)
- Ah-receptor controlled luciferase expression: A novel species-specific bioassay for Ah-receptor active compounds in environmental matrices (1995) (0)
- Interference between Progesterone and Dioxin Signal (1998) (0)
- Interference of polychlorinated biphenyl (PCB) congeners with the CYP1 catalyc activity in flounder (Platichtys Flesus). (1998) (0)
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