Abraham A. Brouwer

Abraham A. Brouwer's AcademicInfluence.com Rankings

Abraham A. Brouwer

Chemistry

#5013

World Rank

#6115

Historical Rank

Organic Chemistry

#838

World Rank

#939

Historical Rank

chemistry Degrees

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Chemistry

Abraham A. Brouwer's Degrees

PhD Chemistry University of Amsterdam
Masters Chemistry University of Amsterdam
Bachelors Chemistry University of Amsterdam

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Abraham A. Brouwer's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. (2000) (891)
In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds. (2001) (744)
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. (2006) (686)
Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health (1998) (622)
Effects of Dioxins and Polychlorinated Biphenyls on Thyroid Hormone Status of Pregnant Women and Their Infants (1994) (499)
Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. (1999) (441)
Polychlorinated biphenyl (PCB)-contaminated fish induces vitamin A and thyroid hormone deficiency in the common seal (Phoca vitulina) (1989) (382)
Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1996) (377)
Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. (2000) (366)
Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water. (1996) (358)
Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs. (1999) (340)
Are brominated flame retardants endocrine disruptors? (2003) (328)
Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. (2004) (299)
Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants. (1995) (281)
Activation of the Ah receptor by tryptophan and tryptophan metabolites. (1998) (278)
Binding of a metabolite of 3,4,3',4'-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin. (1986) (273)
Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays. (2008) (253)
Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons. (1996) (249)
Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254). (1996) (243)
Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. (2002) (243)
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). (2008) (227)
Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. (2002) (217)
Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. (1992) (205)
Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats. (1993) (190)
Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays. (2002) (189)
Screening methods for thyroid hormone disruptors. (1999) (181)
Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities. (2006) (179)
Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3'4,4'-hexachlorobiphenyl. (1995) (176)
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. (2002) (173)
In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated aromatic hydrocarbons. (1998) (158)
The risk of endometriosis and exposure to dioxins and polychlorinated biphenyls: a case-control study of infertile women. (2001) (154)
Identification of estrogenic compounds in fish bile using bioassay-directed fractionation. (2004) (150)
Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish. (2008) (149)
Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. (1993) (146)
Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive. (2018) (140)
Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. (2008) (134)
Thyroxine and 3,3',5-triiodothyronine are glucuronidated in rat liver by different uridine diphosphate-glucuronyltransferases. (1991) (131)
Binding of a 3,3', 4,4'-tetrachlorobiphenyl (CB-77) metabolite to fetal transthyretin and effects on fetal thyroid hormone levels in mice. (1996) (130)
Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. (2003) (123)
Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment. (1995) (121)
Chromatographic analysis of endogenous retinoids in tissues and serum. (2003) (120)
Report of the WHO working group on the assessment of health risks for human infants from exposure to PCDDs, PCDFs and PCBs. (1998) (114)
Biochemical and toxic effects of polychlorinated biphenyls (PCBs), dibenzo-P-dioxins (PCDDs) and dibenzofurans (PCDFs) in the cormorant (phalacrocorax carbo) after in ovo exposure (1994) (110)
Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption (2004) (108)
Role of biotransformation in PCB-induced alterations in vitamin A and thyroid hormone metabolism in laboratory and wildlife species. (1991) (102)
A Novel in Vivo Bioassay for (Xeno-)estrogens Using Transgenic Zebrafish (2000) (99)
Effects of PCDDs, PCDFs and PCBs in common tern (sterna hirundo) breeding in estuarine and coastal colonies in the netherlands and belgium (1995) (97)
Validation and use of the CALUX-bioassay for the determination of dioxins and PCBs in bovine milk. (1998) (95)
Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls. (1998) (94)
In vitro metabolism of 3,3',4,4'-tetrachlorobiphenyl in relation to ethoxyresorufin-O-deethylase activity in liver microsomes of some wildlife species and rat. (1994) (93)
Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER‐CALUX reporter gene assay (2002) (93)
Effects of Polychlorinated Biphenyls (PCBs) and Dioxins on Growth and Development (1994) (93)
Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats. (2004) (92)
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. (2013) (89)
PAH-CALUX, an optimized bioassay for AhR-mediated hazard identification of polycyclic aromatic hydrocarbons (PAHs) as individual compounds and in complex mixtures. (2013) (86)
In vitro characterization of the effectiveness of enhanced sewage treatment processes to eliminate endocrine activity of hospital effluents. (2013) (86)
Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses. (2006) (85)
Identification of 4-Hydroxyheptachlorostyrene in Polar Bear Plasma and Its Binding Affinity to Transthyretin: A Metabolite of Octachlorostyrene? (2000) (82)
Study on the mechanism of interference of 3,4,3',4'-tetrachlorobiphenyl with the plasma retinol-binding proteins in rodents. (1988) (80)
Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition. (1998) (77)
SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part I–model design and effect‐based trigger values (2017) (76)
Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls. (1989) (75)
Extrathyroidal effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone turnover in male Sprague-Dawley rats. (1997) (75)
The calux (chemical‐activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma (1997) (75)
Structure of human transthyretin complexed with bromophenols: a new mode of binding. (2000) (72)
Detection of anabolic androgenic steroid abuse in doping control using mammalian reporter gene bioassays. (2009) (71)
In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems. (2002) (71)
Marked alterations in retinoid homeostasis of Sprague-Dawley rats induced by a single i.p. dose of 10 micrograms/kg of 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1989) (71)
Environmental Occurrence, Analysis and Toxicology of Toxaphene Compounds (1999) (69)
Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells. (2002) (69)
Long-term alterations in regional brain serotonin metabolism following maternal polychlorinated biphenyl exposure in the rat. (1996) (65)
Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys. (1988) (64)
Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats. (2004) (64)
Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines. (1995) (62)
Health risks to infants from exposure to PCBs, PCDDs and PCDFs (2000) (61)
Persistent alterations in regional brain glial fibrillary acidic protein and synaptophysin levels following pre- and postnatal polychlorinated biphenyl exposure. (1996) (57)
Agaricus bisporus and its by-products as a source of valuable extracts and bioactive compounds. (2019) (57)
In vitro inhibition of thyroid hormone sulfation by polychlorobiphenylols: isozyme specificity and inhibition kinetics. (1998) (56)
Effects of polyhalogenated aromatic hydrocarbons (PHAHs) on biochemical parameters in chicks of the common tern (Sterna hirundo) (1994) (56)
Impaired cellular immune response in rats exposed perinatally to Baltic Sea herring oil or 2,3,7,8-TCDD (1997) (53)
Biochemical and physiological approaches in ecotoxicology. (1990) (53)
Comparison of chemical-activated luciferase gene expression bioassay and gas chromatography for PCB determination in human serum and follicular fluid. (2000) (52)
Interference between Progesterone and Dioxin Signal Transduction Pathways (1998) (51)
Metabolism and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl in pregnant and fetal rats. (1995) (51)
Endocrine effects of polycyclic musks: do we smell a rat? (2008) (51)
Environmental occurrence, analysis, and toxicology of toxaphene compounds. (1999) (50)
The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study. (1993) (49)
Time and dose responses of the reduction in retinoid concentrations in C57BL/Rij and DBA/2 mice induced by 3,4,3',4'-tetrachlorobiphenyl. (1985) (49)
Effects of subchronic exposure to complex mixtures of dioxin-like and non-dioxin-like polyhalogenated aromatic compounds on thyroid hormone and vitamin A levels in female Sprague-Dawley rats. (2001) (49)
Biomonitoring of estrogenic exposure and identification of responsible compounds in bream from Dutch surface waters (2007) (47)
Early and differential decrease in natural retinoid levels in C57BL/Rij and DBA/2 mice by 3,4,3',4'-tetrachlorobiphenyl. (1984) (46)
Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor. (2007) (46)
Sample preparation method for the ER-CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts. (2007) (46)
Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development. (2010) (44)
Effects of pentachlorophenol and hydroxylated polychlorinated biphenyls on thyroid hormone conjugation in a rat and a human hepatoma cell line. (1999) (42)
Contribution of planar (0-1 ortho) and nonplanar (2-4 ortho) fractions of Aroclor 1260 to the induction of altered hepatic foci in female Sprague-Dawley rats. (2000) (42)
Interaction of polybrominated biphenyls ether metabolites (PBDE-OH) with human transthyretin in vitro. (1998) (41)
Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs. (2010) (41)
Effects of iron-ore mining and processing on metal bioavailability in a tropical coastal lagoon (2008) (41)
Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like PCBs in mouse hepatoma cells (Hepa1c1c7): involvement of the Ah receptor. (1994) (40)
Host resistance to rat cytomegalovirus (RCMV) and immune function in adult PVG rats fed herring from the contaminated Baltic Sea (1996) (40)
Distribution of the flame retardant tetrabromobisphenol A in pregnant and fetal rats and effect on thyroid hormone homeostasis (1999) (39)
Polybrommated diphenyl ethers (PCDs) as Ah-receptor agonists and antagonists. (1998) (38)
Chronic and reproductive toxicity of a mixture of 15 methylsulfonyl‐polychlorinated biphenyls and 3‐methylsulfonyl‐2,2‐bis‐(4‐chlorophenyl)‐1,1‐dichloroethene in mink (Mustela vison) (1999) (38)
Low hepatic 7-ethoxyresorufin-O-deethylase (EROD) activity and minor alterations in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50. (1996) (38)
Toxic and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl (CB-77) and clophen A50 on eider duckling (Somateria mollissima) in a semi-field experiment. (1994) (37)
Comprehensive evaluation of dioxins and dioxin-like compounds in surface soils and river sediments from e-waste-processing sites in a village in northern Vietnam: Heading towards the environmentally sound management of e-waste (2016) (37)
Fetal, neonatal, and long-term alterations in hepatic retinoid levels following maternal polychlorinated biphenyl exposure in rats. (1995) (36)
Alterations in plasma and hepatic retinoid levels in flounder (Platichthys flesus) after chronic exposure to contaminated harbour sludge in a mesocosm study (1998) (35)
A Panel of Quantitative Calux® Reporter Gene Assays for Reliable High‐Throughput Toxicity Screening of Chemicals and Complex Mixtures (2013) (35)
Ah-receptor mediated luciferase expression: a tool for monitoring dioxin-like toxicity. (1993) (34)
Interference of polychlorinated biphenyls in thyroid hormone metabolism: possible neurotoxic consequences in fetal and neonatal rats. (1992) (33)
High induction of cytochrome p4501a activity without changes in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (1997) (32)
Identification of major dioxin-like compounds and androgen receptor antagonist in acid-treated tissue extracts of high trophic-level animals. (2011) (32)
Biological validation of a sample preparation method for ER-CALUX bioanalysis of estrogenic activity in sediment using mixtures of xeno-estrogens. (2006) (31)
Application of the chemical-activated luciferase expression (CALUX) bioassays for quantification of dioxin-like compounds in small samples of human milk and blood plasma. (1996) (31)
Biotransfiormation and Toxicity of Halogenated Benzenes (1994) (30)
Interactive effects of 2,2'-4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone, vitamin A, and vitamin K metabolism in the rat. (1992) (30)
Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms. (2005) (30)
Steroid hormonal bioactivities, culprit natural and synthetic hormones and other emerging contaminants in waste water measured using bioassays and UPLC-tQ-MS. (2018) (30)
Screening white-rot fungi for bioremediation potential of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2019) (29)
Antimicrobial activity and carbohydrate metabolism in the bacterial metagenome of the soil-living invertebrate Folsomia candida (2019) (28)
Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis. (2014) (27)
SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part II–field feasibility survey (2017) (27)
Induction of altered hepatic foci by a mixture of dioxin-like compounds with and without 2,2',4,4',5,5'-hexachlorobiphenyl in female Sprague-Dawley rats. (1999) (26)
The use of biochemical parameters in comparative toxicological studies with the cormorant () in the Netherlands (1992) (26)
Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan. (2015) (26)
Thyroxine binding to transthyretin Met 119 (1997) (26)
Early decrease in retinoid levels in mice after exposure to low doses of polychlorinated biphenyls (1983) (25)
Bio/chemical Analysis of Dioxin-like Compounds in Sediment Samples from Osaka Bay, Japan (2005) (25)
Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity. (2005) (24)
Occurrence of endophytic bacteria in Vietnamese Robusta coffee roots and their effects on plant parasitic nematodes (2019) (23)
Comparison of dioxin and PCB concentrations in human breast milk samples from Hong Kong and the Netherlands (2003) (23)
Maternal diet and dioxin-like activity, bulky DNA adducts and micronuclei in mother-newborns. (2012) (23)
Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: relevant exposure measures for endocrine disruptors in epidemiologic studies? (2011) (22)
Production of novel recombinant cell line bioassay systems for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. (1993) (22)
The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays (2018) (22)
Evolutionary ecology of beta‐lactam gene clusters in animals (2017) (22)
beta-Naphthoflavone- and self-induced metabolism of 3,3',4,4'-tetrachlorobiphenyl in hepatic microsomes of the male, pregnant female and foetal rat. (1995) (21)
Alterations in retinoid concentrations in several extrahepatic organs of rats by 3,4,3',4'-tetrachlorobiphenyl. (1988) (20)
Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. (2018) (20)
Application of CALUX bioassay system for the detection of dioxin-like chemicals (Ah receptor ligands) in whole serum samples and in extracts from commercial and consumer products. (1996) (20)
Statement From the Work Session On Environmental Endocrine-Disrupting Chemicals: Neural, Endocrine, and Behavioral Effects (1998) (19)
Newborn infants diagnosed as neurologically abnormal with relation to PCB and dioxin exposure and their thyroid-hormone status. (1997) (19)
Determination of the endocrine disrupting potency of hydroxylated PCB's and flame retardants with in vitro bioassays (2002) (18)
Enzyme induction and alterations in thyroid hormone, vitamin A and K levels by TCDD in neonatal and maternal rats (1990) (17)
Application of the CALUX (chemical activated luciferase gene expression) assay for measuring TCDD-equivalents in sediment, pore water and blood plasma samples. (1996) (16)
Subchronic toxicity and reproduction effects of tri-n-butyltin oxide in Japanese quail (1992) (16)
Formation of polybrominated dibenzofurans (PBDFs) after heating of a salmon sample spiked with decabromodiphenyl ether (BDE-209) (2015) (16)
Patterns of variability of retinol levels in a harbour porpoise population from an unpolluted environment (1999) (15)
Screening for PCDD/Fs and dl-PCBs in local and imported food and feed products available across the State of Kuwait and assessment of dietary intake. (2014) (15)
3,4,3',4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. I. Serum and Hepatic Retinoid Reduction and Morphologic Changes (1989) (15)
3,4,3',4'-Tetrachlorobiphenyl distribution and induced effects in the rat adrenal gland. Localization in the zona fasciculata. (1990) (15)
Inhibition of intercellular communication and induction of ethoxyresorufin-O-deethylase activity by polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans in mouse hepa1c1c7 cells. (1996) (14)
Effects on thyroid hormone metabolism and depletion of lung vitamin A in rats by airborne particulate matter. (1993) (14)
Dioxin type and mixed type induction of the cytochrome P-450 system of common eider ducklings (Somateria mollissima) by PCBs: with indications for biotransformation. (1995) (14)
Harmonised quality criteria for chemical and biossays analyses of PCDDs/PCDFs in feed and food part 2: General considerations, biossay methods (2001) (14)
Toxicokinetics of an environmentally relevant mixture of dioxin-like PHAHs with or without a non-dioxin-like PCB in a semi-chronic exposure study in female Sprague Dawley rats. (1998) (13)
Determination of dioxin- and estrogen-like activity in sediment extracts using in vitro CALUX assays. (1996) (12)
DR- and ER-CALUX assays as tools to direct toxicity identification and evaluation of endocrine disrupting chemicals (2002) (12)
Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachlorobiphenyl. (1993) (12)
Effects of outdoor and indoor airborne particulate matter on thyroid hormone and vitamin A metabolism. (1994) (11)
CAFLUX, a simplified version of the CALUX assay for Ah receptor (ant)agonist, based on enhanced green fluorescent protein (EGFP) reporter gene expression. (1998) (11)
In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins (2021) (11)
Toxicological risks to humans of toxaphene residues in fish (2012) (11)
Assessing Indoor Dust Interference with Human Nuclear Hormone Receptors in Cell-Based Luciferase Reporter Assays (2021) (11)
DR-CALUX®- and EROD-TEF values for dioxin-like compounds (PXBs/PXDDs/Fs; X=Br, Cl) and others (e.g. PAHs) (2001) (11)
Developing potency factors for thyroid hormone disruption by PFASs using TTR-TRβ CALUX® bioassay and assessment of PFASs mixtures in technical products. (2021) (11)
Dr‐Calux®: A High‐Throughput Screening Assay for the Detection of Dioxin and Dioxin‐Like Compounds in Food and Feed. (2013) (10)
Evaluation of a panel of in vitro methods for assessing thyroid receptor β and transthyretin transporter disrupting activities. (2020) (10)
Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays. (2020) (10)
Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin biodegradation by extracellular lignin-modifying enzymes from ligninolytic fungus. (2021) (9)
In vitro screening of the endocrine disrupting potency of brominated flame retardants and their metabolites (2004) (9)
Subchronic toxicity of Baltic herring oil and its fractions in the rat II: Clinical observations and toxicological parameters. (2002) (8)
Structure dependent multiple interactions of polyhalogeneted aromatic hydrocarbons with the thyroid hormone system. (1998) (8)
Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes. (2019) (8)
Antagonistic effects on mono- and di-ortho-substituted polychlorinated biphenyls in the ethoxy-resorufin-o-diethylase activity and the luciferase reporter gene assay in vitro. (1998) (8)
Species-specific differences in Ah receptor ligand binding and transcriptional activation: implications for bioassays for the detection of dioxin-like chemicals. (1995) (8)
Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays (2017) (8)
In vitro and in vivo tumor promoting potency of technical toxaphene, uv-irradiated toxaphene, and biotransformed toxaphene (2000) (8)
3,4,3,4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. II. Electron Microscopic Autoradiographic Localization of H-TCB (1989) (8)
Genome annotation and antimicrobial properties of Bacillus toyonensis VU‐DES13, isolated from the Folsomia candida gut (2019) (8)
Hepatic retinoid levels in seven fish species (teleosts) from a tropical coastal lagoon receiving effluents from iron‐ore mining and processing (2012) (7)
Effect of Aroclor 1254 on thyroid hormone sulfation in fetal rats. (1998) (7)
The effect of 3,3′,4,4′-tetrachlorobiphenyl and clophen A50 on the hepatic monooxygenase system of Eider Ducklings (Somateria mollissima) with indications for structure-related biotransformation of CB congeners (1992) (7)
Prenatal exposure of rats to hydroxylated PCBs and some brominated flame retardants (2006) (7)
Versicolorin A enhances the genotoxicity of Aflatoxin B1 in human liver cells by inducing the transactivation of the Ah-Receptor. (2021) (7)
Synergistic Effect of 2,2 prime ,4,4 prime ,5,5 prime -Hexachlorobiphenyl and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Hepatic Porphyrin Levels in the Rat (1996) (7)
Cross-validation study of the DR-CALUX®-bioassay Comparison to Micro-EROD bioassay and chemical analyses (2001) (6)
Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort. (2020) (6)
Effects of retinoic acid on the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced differentiation of in vitro cultured human keratinocytes. (1994) (6)
Development of improved DR-CALUX bioassay for sensitive measurement of aryl hydrocarbon receptor activating compounds (2002) (6)
CONTEMPORARY RELEVANCE OF DIOXIN AND DIOXIN LIKE COMPOUND CONTAMINATIONS IN RESIDUES FROM RECYCLING OF HCH WASTE (2006) (6)
Effects of prenatal exposure to hydroxylated PCB metabolites and some brominated flame retardants on the development of rats (2004) (6)
Observation of an extremely high dioxin level in a human serum sample from ukraine by Dr Calux®, which was confirmed to be 2,3,7,8-tetrachlorodibenzo-p-dioxin by gc-hrms (2005) (6)
Interactive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and retinoids on proliferation and differentiation in cultured human keratinocytes: quantification of cross-linked envelope formation (2009) (6)
Evaluation of tumour promoting potency of fish borne toxaphene residues, as compared to technical toxaphene and UV-irradiated toxaphene. (2008) (5)
Effect-based detection of synthetic glucocorticoids in bovine urine (2015) (5)
Post-mortem stability of blubber DLCs, PCB and tDDT in by-caught harbour porpoises (Phocoena phocoena). (2007) (5)
A low volume method for the analysis of dioxins and dioxin-like compounds in serum and whole blood using BDS¿ Dr Calux® Bioassay (2004) (5)
Effects of PCBs and dioxins during pregnancy and breast feeding on growth and development of newborn infants. A study design and preliminary results. (1992) (4)
Correlating Biodegradation Kinetics of 2,4-Dichlorophenoxyacetic Acid (2,4-D) and 2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T) to the Dynamics of Microbial Communities Originating From Soil in Vietnam Contaminated With Herbicides (2021) (4)
Biodegradation of Fipronil: Transformation Products, Microbial Characterisation and Toxicity Assessment (2021) (4)
Analysis of PCB congeners (by GC-ECD) and dioxin-like toxic equivalence (by CALUX assay) in females with endometriosis and other fertility problems (1999) (4)
Peregrine falcon egg pollutants (2016) (4)
Effects of hydroxy-dioxins on thyroid hormone binding to transthyretin and thyroid hormone type 1 deiodinase activity in vitro and in vivo. (1993) (4)
Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DRhuman CALUX reporter gene assay. (2021) (4)
Perinatal alterations of thyroid homeostasis and long-term neurochemical alterations in rats following maternal Aroclor 1254 exposure. (1994) (4)
Prenatal Aroclor 1254 exposure selectively alters regional glial fibrillary acidic protein levels in the rat brain. (1993) (4)
Anti-androgenic compounds in breast milk and cryptorchidism among Norwegian boys in the HUMIS birth cohort. (2021) (4)
Hydroxylated PCBs (OH‐PCBs) as potential endocrine disrupters ‐ exposures and toxic effects (2001) (4)
Assessment of (anti)oestrogenic compounds using a stably transfected luciferase reporter gene assay in the human T47-D breast cancer cell line. (1998) (4)
A risk-based field and laboratory approach to assess endocrine disruptions in wildlife. (1998) (4)
Flame retardants, polychlorinated biphenyls and insecticides in pregnant women in the northern part of the Netherlands (2004) (4)
Survey of toxaphene concentrations in fish from European waters (2000) (3)
668 Effects of 4-OH-CB 107 and 4-OH-CB 187 on development and endocrine status of the rat (2003) (3)
Antagonistic effects of diortho PCBs (PCB 52 and 128) on Ah receptor-mediated induction of luciferase activity by 3,3',4,4'-tetrachlorobiphenyl (PCB 77) in mouse Hepa-1c1c7 cells. (1993) (3)
Macrophages influence gap junctional intercellular communication between smooth muscle cells in a co-culture model. (1998) (3)
Modulating effects of thyroid state on the induction of biotransformation enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1998) (3)
Thyroid hormone binding proteins as targets for hydroxylated PCB, PCDD and PCDF metabolites; an overview. (1994) (3)
PCB destruction by catalytic hydrodechlorination (CHD) and t-BuOK method: combinatorial bio/chemical analysis (2001) (3)
Peregrine falcon egg pollutants: Mirror Stockholm POPs list including methylmercury (2016) (3)
Identification of PPAR-activating compounds in herbal and edible plants and fungi from Vietnam (2019) (3)
Calux® reporter cell lines as sensitive bioassay for monitoring biological activity of various classes of steroid hormones revert the repressive effect of TCDD on the estrogen receptor (2003) (3)
Degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) by fungi originating from Vietnam (2022) (3)
Species and Metabolic Pathways Involved in Bioremediation of Vietnamese Soil From Bien Hoa Airbase Contaminated With Herbicides (2021) (2)
Elucidating fungal Rigidoporus species FMD21 lignin-modifying enzyme genes and 2,3,7,8-tetrachlorodibenzo-p-dioxin degradation by laccase isozymes. (2021) (2)
Effect on retinoid homeostasis in the flounder (Platichtys flesus) following chronic exposure to contaminated harbour dredge spoil from Rotterdam harbour. (1996) (2)
Low hepatic ethyoxyresorufin-o-deethylase (EROC) induction with no detectable cytosolic Ah-receptor levels in Flounder (Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50. (1993) (2)
Project proposal. Evaluating human health risk from low-dose and long-term exposure to polychlorinated biphenyls. (2000) (2)
Altered thyroxine binding to amyloidogenic and non-amyloidogenic transthyretin variants: TTR Met 119 and TTR Pro 55 (1996) (2)
Validation of extraction, clean-up and Dr Calux® bioanalysis.Part I: Feedingstuff (2004) (2)
Developments in analysis and toxicology of toxaphene compounds. (1998) (2)
GR CALUX assay detects synthetic glucocorticoids in calf urine: a validation study (2019) (2)
Glucocorticoid mediated expression of dioxin target genes in rat H4IIe cells but not in human HepG2 and T47D cells (2006) (2)
Induction of biotransformation enzymes by polyhalogenated aromatic hydrocarbons (PHAHs): potential impact on animal physiology and health (1999) (2)
Effect-directed analysis and chemical identification of agonists of peroxisome proliferator-activated receptors in white button mushroom. (2020) (1)
Investigation of the soil nematode community composition in a monoculture Robusta coffee plantation in Dak Lak, Vietnam (2021) (1)
Evaluation of potential bioaccumulative compounds exerting endocrine-disrupting activities in wild animals using vitro bioassays and chemical fractionation (2010) (1)
Tumour promotion induction by complex mixtures of 2-4 and 0-1 ortho polychlorinated biphenyls in female sprague Dawley rats. (1998) (1)
Systematic surveillance for management of Dioxin contamination risks in the food chain: Germany and related cases (2012) (1)
Binding of several hydroxychlorobiphenyls to the thyroid hormone transport protein, transthyretin. (1993) (1)
Endocrine activities of phthalate alternatives; assessing the safety profile of furan dicarboxylic acid esters using a panel of human cell based reporter gene assays (2020) (1)
Applications of in Vitro Screening Tools to Support Risk Assessment of Brominated Flame Retardants (2006) (1)
Correlating biodegradation kinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the dynamics of microbial communities originating from soil in Vietnam contaminated with herbicides and dioxins (2022) (1)
Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings. (2022) (1)
In vitro metabolism of 3,4,3',4,4'-tetrachlorobiphenyl by microsomes of wildlife species compared to the rat. (1993) (1)
Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): possible role of the Ah-receptor. (1993) (1)
Estrogenic mixture effects in the ER-CALUX® assay used for the biological validation of an extraction and clean up method for sediments (2005) (0)
Responses of mixtures of polyhalogenated aromatic compounds or single compounds in the CALUX-assay a novel species-specific bioassay for Ah-receptor active compounds (1995) (0)
Phenolic organohalogen-thyroid hormone disruptors: mechanisms and neurochemical consequences for animal offspring. (1998) (0)
Non-additive inductions of altered hepatic foci in female sprague Dawley rats by a mixture of dioxin-like compounds. (1996) (0)
A genomics approach to identifying mechanisms of developmental toxicity in zebrafish (2008) (0)
Molecular characterization of the Ah-receptor pathway in flounder (Platichtys flesus). (1998) (0)
Screening the hormonal activity of endocrine disruptors chemicals in food contact materials with Reporter Gene Assays: A first screening step (2016) (0)
Extraction and bioanalysis of arylhydrocarbon- and estrogen- receptor active compounds (1997) (0)
Vitamin A reduction in Eider ducklings (Somateria mollissima) exposed to polychlorinated biphenyls (CB-77 and Clophen A50). (1993) (0)
Introduction of a linear 2,3,7,8-TCDD curve-fit as a means to Improve performance characteristics of the (2005) (0)
Application of in vitro and in vivo reporter gene assays for assessing (mixtures of) estrogenic substances (2001) (0)
Paleotoxicity of petrogenic and pyrogenic hydrocarbon mixtures in sediment cores from the Athabasca oil sands region, Alberta (Canada). (2021) (0)
Identification and risk assessment of endocrine disrupting compounds. Part I: toxicity profile measurements in Dutch aquatic sediments (2001) (0)
Hagenmaier drum - fly ash Dechlorination/ hydrogenation process: Combinatorial bio/chemical analysis (2001) (0)
115 EFFECTS OF DIOXINS AND POLYCHLORINATED BIPHENYLS ON THYROID HORMONE STATUS OF PREGNANT WOMEN AND THEIR INFANTS (1994) (0)
Antagonistic effects of retinoic acid on the 2,3,7,8-tetrachlordibenzo-p-dioxin induced differentiation of in vitro cultured human keratinocytes. (1993) (0)
Degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) by fungi originating from Vietnam (2022) (0)
Identification of dioxin-like and estrogenic compounds in sediment using Calux® assay-directed fractionation combined with two-dimensional comprehensive GCxGC-TOF MS (2004) (0)
The first BIO-survey on synthetic glucocorticoid abuse in food producing bovines (2015) (0)
In vitro genotoxicity and tumor promoting potency of technical toxaphene, uv-irridiated toxaphene, and weathered toxaphene (2000) (0)
Toxicological response in rats fed Baltic Sea Herring oil and its fractions for 13 weeks. (1998) (0)
Development of Calux bioassay-based systems as instruments to detect hormones and contaminants (2006) (0)
Bioanalytical Detection of Steroid Abuse in Sports Based on the Androgenic Activity Measurement (2021) (0)
Development of a toxicity identification and evaluation method for estrogenic chemicals in fish bile (2004) (0)
A Functional Carbohydrate Degrading Enzyme Potentially Acquired by Horizontal Gene Transfer in the Genome of the Soil Invertebrate Folsomia candida (2022) (0)
Measurement of (anti-)oestrogenic potency in complex mixtures using a novel stably transfected luciferase reporter gene assay in the human T47D breast cancer cell (2000) (0)
Improving infant food safety by avoiding hazards of chemical mixture effects using novel integrated methods based on bioassays and analytical chemistry (2022) (0)
Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays (2016) (0)
Geochemistry, bioavailability, bioaccumulation and toxicology of trace metals related to iron ore mining - Case study: Samarco Mineraçao (2005) (0)
Inter-laboratory Calibration Study for Dioxins in Food/Feedstuff using DR-CALUX Assay (2007) (0)
Synthetic glucocorticoids in bovine urine: From targeted to untargeted detection (2013) (0)
Expression profiling of zebrafish embryonic fibroblast cells exposed to 6-OH-BDE 47 (2006) (0)
In vivo promoting potency of technical toxaphene, uv-irridiated toxaphene, and weathered toxaphene (2000) (0)
Ah-receptor controlled luciferase expression: A novel species-specific bioassay for Ah-receptor active compounds in environmental matrices (1995) (0)
Interference between Progesterone and Dioxin Signal (1998) (0)
Interference of polychlorinated biphenyl (PCB) congeners with the CYP1 catalyc activity in flounder (Platichtys Flesus). (1998) (0)

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