Adam Eyre-Walker

Adam Eyre-Walker's AcademicInfluence.com Rankings

Adam Eyre-Walker

Biology

#10356

World Rank

#13682

Historical Rank

biology Degrees

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Biology

Why Is Adam Eyre-Walker Influential?

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According to Wikipedia, Adam C. Eyre-Walker, is a British evolutionary geneticist, currently Professor of Biology in the School of Life Sciences at the University of Sussex. He is noted for making "significant contributions to our understanding of evolution at the molecular level" and pioneering the use of DNA sequence databases for extracting information about the evolution of genomes.

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Adam Eyre-Walker's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The distribution of fitness effects of new mutations (2007) (1233)
Adaptive protein evolution in Drosophila (2002) (653)
The evolution of isochores (2001) (404)
Variation in the mutation rate across mammalian genomes (2011) (403)
Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. (2009) (397)
High genomic deleterious mutation rates in hominids (1999) (375)
Evidence of Selection upon Genomic GC-Content in Bacteria (2010) (363)
Investigation of the bottleneck leading to the domestication of maize. (1998) (349)
The Distribution of Fitness Effects of New Deleterious Amino Acid Mutations in Humans (2006) (342)
Joint Inference of the Distribution of Fitness Effects of Deleterious Mutations and Population Demography Based on Nucleotide Polymorphism Frequencies (2007) (330)
Synonymous codon usage in Escherichia coli: selection for translational accuracy. (2006) (324)
Linkage disequilibrium and recombination in hominid mitochondrial DNA. (1999) (312)
The genomic rate of adaptive evolution. (2006) (304)
Molecular Evolution by Wen-Hsiung Li. Published by Sinauer Associates, Sunderland, MA, USA. ISBN: 0-87893-463-4 (cloth). (1997) (247)
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. (2010) (239)
Changing effective population size and the McDonald-Kreitman test. (2002) (238)
Recombination and mammalian genome evolution (1993) (238)
Genome wide analyses reveal little evidence for adaptive evolution in many plant species. (2010) (232)
The genomic rate of adaptive amino acid substitution in Drosophila. (2004) (227)
Evidence for Widespread Degradation of Gene Control Regions in Hominid Genomes (2005) (220)
Estimation of the neutrality index. (2011) (218)
Deleterious mutations and the evolution of sex. (2000) (216)
Translational selection and molecular evolution. (1998) (213)
Synonymous codon bias is related to gene length in Escherichia coli: selection for translational accuracy? (1996) (210)
Quantifying the slightly deleterious mutation model of molecular evolution. (2002) (209)
Population size and the rate of evolution. (2014) (203)
How clonal are human mitochondria? (1999) (194)
The Assessment of Science: The Relative Merits of Post-Publication Review, the Impact Factor, and the Number of Citations (2013) (190)
Evidence of selection on silent site base composition in mammals: potential implications for the evolution of isochores and junk DNA. (1999) (189)
A broad survey of recombination in animal mitochondria. (2004) (188)
The McDonald-Kreitman test and slightly deleterious mutations. (2008) (183)
Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies (2010) (168)
The rate of adaptive evolution in enteric bacteria. (2006) (165)
The distribution of bacterial doubling times in the wild (2017) (165)
Reduced synonymous substitution rate at the start of enterobacterial genes. (1993) (165)
The Effect of Variation in the Effective Population Size on the Rate of Adaptive Molecular Evolution in Eukaryotes (2012) (150)
Fundamentals of Molecular Evolution (2nd edn) (2000) (148)
Terumi Mukai and the riddle of deleterious mutation rates. (1999) (145)
Hundreds of putatively functional small open reading frames in Drosophila (2011) (131)
Questioning evidence for recombination in human mitochondrial DNA. (2000) (128)
Evidence for Pervasive Adaptive Protein Evolution in Wild Mice (2010) (125)
Rates of Lateral Gene Transfer in Prokaryotes: High but Why? (2015) (123)
Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila. (2004) (117)
Evidence for Variation in the Effective Population Size of Animal Mitochondrial DNA (2009) (112)
Cryptic Variation in the Human Mutation Rate (2009) (110)
Correlated rates of synonymous site evolution across plant genomes. (1997) (110)
A Method for Inferring the Rate of Occurrence and Fitness Effects of Advantageous Mutations (2011) (108)
Human disease genes: patterns and predictions. (2003) (104)
The rate of adaptive evolution in animal mitochondria (2015) (101)
Estimating the distribution of fitness effects from DNA sequence data: Implications for the molecular clock (2003) (92)
Does Human mtDNA Recombine? (2001) (91)
What can we learn about the distribution of fitness effects of new mutations from DNA sequence data? (2010) (88)
Synonymous codon bias is not caused by mutation bias in G+C-rich genes in humans. (2001) (88)
Human Triallelic Sites: Evidence for a New Mutational Mechanism? (2010) (87)
Quantifying the Variation in the Effective Population Size Within a Genome (2011) (87)
A new perspective on isochore evolution. (2006) (84)
The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution rates: implications for the correlation between the synonymous substitution rate and codon usage bias. (2003) (81)
An analysis of codon usage in mammals: Selection or mutation bias? (1991) (79)
Problems with Parsimony in Sequences of Biased Base Composition (1998) (79)
The Decline of Isochores in Mammals: An Assessment of the GC ContentVariation Along the Mammalian Phylogeny (2004) (78)
Synonymous substitution rates in enterobacteria. (1995) (78)
The evolution of courtship behaviors through the origination of a new gene in Drosophila (2008) (77)
The large‐scale distribution of somatic mutations in cancer genomes (2012) (77)
Mutation pressure, natural selection, and the evolution of base composition in Drosophila (2004) (74)
An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies (2014) (73)
The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations (2007) (73)
A reanalysis of the indirect evidence for recombination in human mitochondrial DNA (2004) (71)
How and Why DNA Barcodes Underestimate the Diversity of Microbial Eukaryotes (2011) (70)
Adaptive Evolution Is Substantially Impeded by Hill–Robertson Interference in Drosophila (2015) (69)
The evolution of isochores: evidence from SNP frequency distributions. (2002) (69)
Estimating the Rate of Adaptive Molecular Evolution When the Evolutionary Divergence Between Species is Small (2012) (67)
Divergence and Polymorphism Under the Nearly Neutral Theory of Molecular Evolution (2008) (65)
Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans (2018) (60)
An investigation of the variation in the transition bias among various animal mitochondrial DNA. (2005) (60)
A Problem With the Correlation Coefficient as a Measure of Gene Expression Divergence (2009) (59)
Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem? (2017) (59)
Mitochondrial Steve: paternal inheritance of mitochondria in humans (2003) (58)
Population genomics of picophytoplankton unveils novel chromosome hypervariability (2017) (58)
Spontaneous Mutation Rate in the Smallest Photosynthetic Eukaryotes (2017) (54)
Do mitochondria recombine in humans? (2000) (50)
Differentiating between selection and mutation bias. (1997) (49)
The positive correlation between dN/dS and dS in mammals is due to runs of adjacent substitutions. (2011) (45)
Research groups: How big should they be? (2015) (44)
A Resolution of the Mutation Load Paradox in Humans (2012) (43)
Evidence that both G + C rich and G + C poor isochores are replicated early and late in the cell cycle. (1992) (42)
Variation in synonymous codon use and DNA polymorphism within the Drosophila genome (2006) (41)
The Effect of Transposable Element Insertions on Gene Expression Evolution in Rodents (2009) (39)
The correlation between linkage disequilibrium and distance: implications for recombination in hominid mitochondria. (2001) (38)
Transposable elements: insertion pattern and impact on gene expression evolution in hominids. (2010) (37)
Analysis of the Phylogenetic Distribution of Isochores in Vertebrates and a Test of the Thermal Stability Hypothesis (2002) (36)
Codon usage bias (2002) (35)
The Accumulation of Gene Regulation Through Time (2011) (34)
Partitioning the variation in mammalian substitution rates. (2003) (33)
Are pangenomes adaptive or not? (2017) (33)
The close proximity ofEscherichia coli genes: Consequences for stop codon and synonymous codon use (1996) (33)
Molecular Evolutionary Consequences of Island Colonization (2016) (31)
The Genomic Distribution and Local Context of Coincident SNPs in Human and Chimpanzee (2010) (31)
Evolutionary genetics: Direct evidence of recombination in human mitochondrial DNA (2004) (31)
The Compositional Evolution of the Murid Genome (2002) (30)
Patterns of Base Composition Within the Genes of Drosophila melanogaster (1998) (28)
Why Are Translationally Sub-Optimal Synonymous Codons Used in Escherichia coli? (2001) (28)
Nearly Neutral Evolution Across the Drosophila melanogaster Genome (2018) (27)
Recommendations for improving statistical inference in population genomics (2021) (26)
DNA mismatch repair and synonymous codon evolution in mammals. (1994) (26)
The muddle about mutations (1997) (26)
Fundamentals of Molecular Evolution . By Li Wen-Hsiung and Graur Dan. Sinauer Associates Inc. 1991. 284 pages. £16.95. ISBN 0 87893 452 9. (1991) (26)
Investigating Evolutionary Rate Variation in Bacteria (2019) (24)
DNA sequence diversity and the efficiency of natural selection in animal mitochondrial DNA (2016) (24)
Reply to Macaulay et al. (1999): mitochondrial DNA recombination-reasons to panic (1999) (24)
Organellar Inheritance in the Green Lineage: Insights from Ostreococcus tauri (2013) (22)
The distance between Escherichia coli genes is related to gene expression levels (1995) (21)
A recombination (1990) (21)
Fluctuating Selection Models and Mcdonald-Kreitman Type Analyses (2013) (20)
Extensive Variation in the Mutation Rate Between and Within Human Genes Associated with Mendelian Disease (2016) (18)
Size Does Not Matter for Mitochondrial DNA (2006) (18)
How Much of the Variation in the Mutation Rate Along the Human Genome Can Be Explained? (2014) (16)
A Selection Index for Gene Expression Evolution and Its Application to the Divergence between Humans and Chimpanzees (2012) (16)
Nucleotide substitution rate estimation in enterobacteria: approximate and maximum-likelihood methods lead to similar conclusions. (2001) (16)
The Excess of Small Inverted Repeats in Prokaryotes (2008) (14)
Response to Kondrashov. (2001) (14)
Does Adaptive Protein Evolution Proceed by Large or Small Steps at the Amino Acid Level? (2018) (13)
A dissection of volatility in yeast. (2005) (13)
Fitness Effects of Spontaneous Mutations in Picoeukaryotic Marine Green Algae (2016) (13)
The comparative population genetics of Neisseria meningitidis and Neisseria gonorrhoeae (2018) (13)
Impact of Mutation Rate and Selection at Linked Sites on DNA Variation across the Genomes of Humans and Other Homininae (2019) (12)
Mitochondrial DNA Sequence Diversity in Mammals: A Correlation between the Effective and Census Population Sizes (2020) (12)
The role of DNA replication and isochores in generating mutation and silent substitution rate variance in mammals. (1992) (12)
ODoSE: A Webserver for Genome-Wide Calculation of Adaptive Divergence in Prokaryotes (2013) (11)
Why Are Young and Old Repetitive Elements Distributed Differently in the Human Genome? (2005) (11)
On the prospect of achieving accurate joint estimation of selection with population history (2022) (10)
The effect of constraint on the rate of evolution in neutral models with biased mutation. (1992) (10)
Understanding the Degradation of Hominid Gene Control (2006) (9)
Evolutionary genomics: reading the bands. (2000) (9)
The Role of Mutation Rate Variation and Genetic Diversity in the Architecture of Human Disease (2013) (7)
A test of whether selection maintains isochores using sites polymorphic for Alu and L1 element insertions. (2002) (7)
Impact of mutation rate and selection at linked sites on fine-scale DNA variation across the homininae genome (2018) (6)
Strong evidence for the adaptive walk model of gene evolution in Drosophila and Arabidopsis (2022) (5)
The outstanding scientist, R.A. Fisher: his views on eugenics and race (2021) (5)
Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors? (2016) (4)
A new test suggests hundreds of amino acid polymorphisms in humans are subject to balancing selection (2022) (4)
Searching for Sequence Directed Mutagenesis in Eukaryotes (2005) (4)
Estimating the Rate of Adaptive Molecular Evolution When the Evolutionary Divergence Between Species is Small (2012) (3)
A Test of Amino Acid Reversibility (2001) (3)
Mitochondrial replacement and its effects on human health. (2019) (3)
Studies of synonymous codon evolution in mammals (1992) (2)
Changing Population Size in McDonald–Kreitman Style Analyses: Artifactual Correlations and Adaptive Evolution between Humans and Chimpanzees (2022) (2)
Correction: How and Why DNA Barcodes Underestimate the Diversity of Microbial Eukaryotes (2012) (2)
A new test suggests that balancing selection maintains hundreds of non-synonymous polymorphisms in the human genome (2021) (2)
Large scale variation in the rate of de novo mutation in humans and its relationship to divergence and diversity. (2017) (2)
Synonymous substitutions are clustered in enterobacterial genes (1994) (2)
Molecular evolutionary consequences of island colonisation 1 2 (2015) (1)
Peer Review #1 of "The comparative population genetics of Neisseria meningitidis and Neisseria gonorrhoeae (v0.2)" (2019) (1)
Data from: Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans (2018) (1)
Patterns of selection in the evolution of a transposable element (2021) (1)
Drosophila of of Evolutionary Constraints in Intronic and Intergenic DNA (2007) (1)
Does very short patch (VSP) repair efficiency vary in relation to gene expression levels? (1995) (1)
An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies (2014) (1)
Evolutionary genetics. The muddle about mutations. (1997) (1)
Site level factors that affect the rate of adaptive evolution in humans and chimpanzees; the effect of contracting population size (2021) (1)
Large scale variation in the rate of de novo mutation, base composition, divergence and diversity in humans (2017) (1)
Testing the adaptive walk model of gene evolution (2021) (1)
Research article Patterns of genetic diversity in populations of two bat species (Sturnira ludovici and Artibeus toltecus) in Cusuco National Park, Honduras (2009) (0)
Base composition patterns (2001) (0)
Mito-nuclear Incompatibilities and Mitochondrial Replacement Therapy (2016) (0)
Are pangenomes adaptive or not? (2017) (0)
interference in Drosophila (2015) (0)
What Determines Levels of Mitochondrial Genetic Diversity in Birds? (2023) (0)
2 Research Groups : How big should they be ? 3 4 (2017) (0)
Editorial (2022) (0)
A substantial number of adaptive mutations are lost to Hill-Robertson Interference in Drosophila (2015) (0)
Editorial (2019) (0)
MITOCHONDRIAL DNA RECOMBINATION : NO NEED TO PANIC. AUTHORS' REPLY (1999) (0)
Signatures of Selection on Mitonuclear Integrated Genes Uncover Hidden Mitogenomic Variation in Fur Seals (2022) (0)
Au th or ' s p er so na l co py A new perspective on isochore evolution (0)
Can we predict the mutation rate at the single nucleotide scale in the human genome (2013) (0)
Molecular evolutionary consequences of island colonisation (2015) (0)
RECENT BOOKS IN PRINT (1996) (0)
Factors That Affect the Rates of Adaptive and Nonadaptive Evolution at the Gene Level in Humans and Chimpanzees (2021) (0)
Au th or ' s pe rs on al co py A new perspective on isochore evolution (2006) (0)
Book reviews (1996) (0)
The silent impact: codon usage bias and protein evolution in bacteria (2022) (0)
An improved genome of the model marine alga [ i ] Ostreococcus tauri [ / i ] unfolds by assessing Illumina (2018) (0)
Adaptive evolution is substantially impeded by Hill-Robertson interference in Drosophila (2015) (0)
1 The comparative population genetics of Neisseria meningitidis and Neisseria gonorrhoeae 2 3 (2019) (0)
The muddle about mutations (Evolutionary genetics) (1997) (0)

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Adam Eyre-Walker is affiliated with the following schools:

University of Sussex