Adriano Fontana

Q: What Schools Are Affiliated With Adriano Fontana

Adriano Fontana is affiliated with the following schools: University of Lausanne, University of California, Berkeley, Stanford University, University of Basel, University of Geneva, University of California, San Francisco, University of Zurich, University of Giessen

Adriano Fontana's AcademicInfluence.com Rankings

Adriano Fontana

Biology

#8664

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#11777

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Cell Biology

#343

World Rank

#352

Historical Rank

Immunology

#503

World Rank

#520

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Molecular Biology

#1119

World Rank

#1144

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Biology

Adriano Fontana's Degrees

Bachelors Biology University of California, Berkeley
PhD Molecular Biology Stanford University

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Adriano Fontana's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape (1996) (1354)
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation (2011) (1096)
Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity (1998) (838)
Astrocytes present myelin basic protein to encephalitogenic T-cell lines (1984) (776)
Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. (1982) (735)
On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases (1989) (699)
Increased Number of Islet-Associated Macrophages in Type 2 Diabetes (2007) (684)
Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells (1987) (619)
[Interleukin 1]. (1985) (571)
Prevention of Islet Allograft Rejection with Engineered Myoblasts Expressing FasL in Mice (1996) (483)
Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate (1991) (438)
Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. (1985) (435)
Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2. (1989) (402)
Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. (2001) (400)
Complementary DNA for human glioblastoma‐derived T cell suppressor factor, a novel member of the transforming growth factor‐beta gene family. (1987) (394)
Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines. (1994) (376)
Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia. (1992) (370)
Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects. (1984) (361)
The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis (1995) (360)
T cell suppressor factor from human glioblastoma cells is a 12.5‐kd protein closely related to transforming growth factor‐beta. (1987) (344)
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). (1999) (320)
IL‐6‐deficient mice resist myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis (1998) (315)
TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription (2007) (313)
Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction? (1984) (274)
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid (1989) (273)
Macrophage‐induced cytotoxicity of N‐methyl‐D‐aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines (1992) (271)
Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. (1995) (271)
Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons. (1994) (269)
Mini‐review: Specificity and expression of CIITA, the master regulator of MHC class II genes (2004) (268)
The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-β, T-cell apoptosis, and the immune privilege of the brain (1995) (267)
The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. (2005) (263)
Production of hemopoietic colony-stimulating factors by astrocytes. (1990) (252)
Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients (1988) (248)
Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients (1988) (231)
Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling (2015) (227)
Severity of symptoms and demyelination in MOG‐induced EAE depends on TNFR1 (1999) (212)
Local Fas/APO‐1 (CD95) ligand‐mediated tumor cell killing in vivo (1995) (208)
Astrocyte-derived interleukin 3 as a growth factor for microglia cells and peritoneal macrophages. (1986) (200)
Mesenteric lymph nodes are critical for the induction of high‐dose oral tolerance in the absence of Peyer's patches (2002) (197)
Tumor Necrosis Factor α and Lymphotoxin α Are Not Required for Induction of Acute Experimental Autoimmune Encephalomyelitis (1997) (195)
The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release (2011) (194)
TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. (2000) (193)
TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription. (2007) (185)
Maturation of Dendritic Cells Is Accompanied by Rapid Transcriptional Silencing of Class II Transactivator (Ciita) Expression (2001) (183)
Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis? (1990) (180)
Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. (1987) (178)
Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. (1994) (173)
Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. (1999) (171)
Astrocytes of the brain synthesize interleukin 3-like factors. (1985) (170)
C-X-C and C-C chemokines are expressed in the cerebrospinal fluid in bacterial meningitis and mediate chemotactic activity on peripheral blood-derived polymorphonuclear and mononuclear cells in vitro. (1997) (166)
Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-γ inducible protein 10 (1999) (166)
Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis (1998) (163)
Immune‐Mediated Encephalitis: On the Role of Antigen‐Presenting Cells in Brain Tissue (1987) (162)
FLIP switches Fas-mediated glucose signaling in human pancreatic β cells from apoptosis to cell replication (2002) (157)
Experimental pneumococcal meningitis: Cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide (1995) (155)
Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. (1992) (155)
TNF‐α and IFN‐γ render microglia sensitive to Fas ligand‐induced apoptosis by induction of Fas expression and down‐regulation of Bcl‐2 and Bcl‐xL (1998) (153)
Chemokines and chemotaxis of leukocytes in infectious meningitis (1998) (152)
Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches (2001) (152)
Puromycin-sensitive Aminopeptidase (1995) (151)
Interleukin-1 derived from astrocytes enhances slow wave activity in sleep EEG of the rat. (1984) (151)
Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. (1990) (151)
Modulation of the immune response by transforming growth factor beta. (1992) (147)
MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity (2010) (146)
Interleukin-6–Deficient Mice Resist Development of Autoimmune Myocarditis Associated With Impaired Upregulation of Complement C3 (2003) (146)
Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis. (1987) (145)
Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice. (1989) (143)
Selective Abrogation of Major Histocompatibility Complex Class II Expression on Extrahematopoietic Cells in Mice Lacking Promoter IV of the Class II Transactivator Gene (2001) (141)
Lack of IL-6 augments inflammatory response but decreases vascular permeability in bacterial meningitis. (2003) (139)
The glioblastoma‐derived T‐cell suppressor factor/transforming growth factor beta2 inhibits the generation of lymphokineactivated killer (LAK) cells (1988) (133)
Fas/APO-1 gene transfer for human malignant glioma. (1995) (132)
Astrocyte-derived TGF-beta 2 and NGF differentially regulate neural recognition molecule expression by cultured astrocytes (1991) (132)
Transforming growth factor‐β2 induces apoptosis of murine T cell clones without down‐regulating bcl‐2 mRNA expression (1994) (125)
Interleukin-6 is elevated in plasma in multiple sclerosis (1991) (125)
The glioblastoma‐derived t cell suppressor factor/ transforming growth factor‐β2 inhibits t cell growth without affecting the interaction of interleukin 2 with its receptor (1988) (123)
Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon‐γ inducible protein‐10 and monocyte chemotactic protein‐1 (1997) (123)
Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse. (1987) (122)
Role of ninjurin‐1 in the migration of myeloid cells to central nervous system inflammatory lesions (2011) (122)
Myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas‐ and Fas ligand‐deficient lpr and gld mice (1997) (121)
The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation (2003) (120)
Interleukin‐16, produced by synovial fibroblasts, mediates chemoattraction for CD4+ T lymphocytes in rheumatoid arthritis (1998) (120)
TGFβ directs gene expression of activated microglia to an anti‐inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes (2003) (119)
Listeria meningitis: identification of a cerebrospinal fluid inhibitor of macrophage listericidal function as interleukin 10 (1993) (117)
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid (1998) (116)
Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity. (1999) (108)
Experimental Listeria meningoencephalitis. Macrophage inflammatory protein-1 alpha and -2 are produced intrathecally and mediate chemotactic activity in cerebrospinal fluid of infected mice. (1995) (107)
Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity. (2001) (106)
Hepatocyte-derived interleukin-6 and tumor-necrosis factor alpha mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes. (1995) (106)
TGF‐β‐treated microglia induce oligodendrocyte precursor cell chemotaxis through the HGF‐c‐Met pathway (2005) (105)
Identification of a SIRT1 mutation in a family with type 1 diabetes. (2013) (102)
Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumococcal meningitis. (1996) (99)
Cancer cell sensitization to Fas-mediated apoptosis by sodium butyrate (1998) (97)
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? (2010) (93)
Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency (2010) (93)
Induction of antitumor immunity with Fas/APO-1 ligand (CD95L)-transfected neuroblastoma neuro-2a cells. (1999) (92)
Production of macrophage colony-stimulating factor by astrocytes and brain macrophages (1992) (91)
Endothelial Cell Barrier Impairment Induced by Glioblastomas and Transforming Growth Factor &bgr;2 Involves Matrix Metalloproteinases and Tight Junction Proteins (2008) (91)
Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection. (2000) (90)
Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis (2000) (89)
The Endothelin System in Human Glioblastoma (2000) (88)
Protease inhibitors interfere with the transforming growth factor-beta-dependent but not the transforming growth factor-beta-independent pathway of tumor cell-mediated immunosuppression. (1992) (88)
Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor (1993) (86)
Mechanisms of brain injury in bacterial meningitis: workshop summary. (1994) (85)
Clock Gene Modulation by TNF-α Depends on Calcium and p38 MAP Kinase Signaling (2009) (85)
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia (1990) (84)
Topoisomerase‐I inhibitors for human malignant glioma: Differential modulation of p53, p21, bax and bcl‐2 expression and of CD95‐mediated apoptosis by camptothecin and β‐lapachone (1997) (83)
Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand. (1999) (83)
Meningitis-Associated Central Nervous System Complications are Mediated by the Activation of Poly(ADP-ribose) Polymerase (2002) (82)
Role of Caspase‐1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase‐1‐deficient mice (2002) (82)
TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis. (1997) (81)
TGF-β-Induced Apoptosis of Cerebellar Granule Neurons Is Prevented by Depolarization (1996) (81)
Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. (1999) (81)
cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. (1993) (80)
Cytokine networks in multiple sclerosis: lost in translation (2010) (79)
TGF‐β induces the expression of the FLICE‐inhibitory protein and inhibits Fas‐mediated apoptosis of microglia (2000) (78)
Transient Production of TGF‐β2 by Postnatal Cerebellar Neurons and its Effect on Neuroblast Proliferation (1994) (74)
In vitro stimulation of glia cells by a lymphocyteproduced factor (1980) (73)
Induction of colitis in mice deficient of Peyer's patches and mesenteric lymph nodes is associated with increased disease severity and formation of colonic lymphoid patches. (2002) (73)
Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO‐1/CD95) pathway (1996) (72)
Biological and biochemical characterization of an interleukin 1‐like factor from rat C6 glioma cells (1983) (71)
Human immunodeficiency virus type-1 Nef protein induces blood–brain barrier disruption in the rat: role of matrix metalloproteinase-9 (2000) (68)
HIV type 1 Nef protein is a viral factor for leukocyte recruitment into the central nervous system. (1999) (68)
Transforming growth factor beta 2 inhibits cerebrovascular changes and brain edema formation in the tumor necrosis factor alpha-independent early phase of experimental pneumococcal meningitis (1992) (66)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblastoma cells. Despite the presence of inducing signals GM-CSF is not expressed in vivo. (1992) (66)
Tumour necrosis factor-alpha in infectious meningitis. (1989) (66)
Apoptosis in proliferative vitreoretinal disorders: possible involvement of TGF-beta-induced RPE cell apoptosis. (1997) (66)
Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-γ (1986) (66)
TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. (1998) (65)
Cloning of the Human Puromycin‐Sensitive Aminopeptidase and Evidence for Expression in Neurons (1997) (65)
Immunobiology of Microglial Cells a (1988) (65)
Variations in anticipatory cognitive stress appraisal and differential proinflammatory cytokine expression in response to acute stress (2007) (64)
Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis. (1995) (63)
Cell type-specific regulation of expression of transcription factor AP-2 in neuroectodermal cells. (1994) (63)
Glia cell stimulating factor (GSF): A new lymphokine Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production (1982) (62)
Transforming growth factor-beta modulates T cell-mediated encephalitis caused by Borna disease virus. Pathogenic importance of CD8+ cells and suppression of antibody formation. (1991) (60)
Effects of interferons and hydrogen peroxide on CA3 pyramidal cells in rat hippocampal slice cultures (1993) (59)
Depression in Autoimmune Diseases. (2016) (59)
Tumor necrosis factor (TNF) ligand and TNF receptor deficiency affects sleep and the sleep EEG. (2002) (57)
Partial purification and biochemical characterization of a T cell suppressor factor produced by human glioblastoma cells. (1985) (57)
Astrocytes and Microglia Produce Interleukin‐12 p40 a (1996) (56)
Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease. (1990) (56)
Inhibition of IL-1β Improves Fatigue in Type 2 Diabetes (2011) (54)
Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels (1988) (53)
Neurons and neuroblastoma as a source of macrophage colony‐stimulating factor (1992) (49)
REVIEW ■ : Activation of Microglia: A Dangerous Interlude in Immune Function in the Brain (1996) (49)
TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis. (2006) (48)
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation. (2010) (45)
Human glioblastoma cell derived transforming growth factor-β2: evidence for secretion of both high and low molecular weight biologically active forms (1991) (44)
Interaction of reovirus with cell surface receptors. II. Generation of suppressor T cells by the hemagglutinin of reovirus type 3. (1980) (44)
NG2 expressed by macrophages and oligodendrocyte precursor cells is dispensable in experimental autoimmune encephalomyelitis. (2011) (43)
Expression of TGF-beta 2 in human glioblastoma: a role in resistance to immune rejection? (1991) (43)
Glia cell stimulating factor (GSF): A new lymphokine Part 2. Cellular sources and partial purification of human GSF (1982) (41)
Immunological Aspects of Epilepsy (1980) (41)
Expression of the HGF receptor c‐met by macrophages in experimental autoimmune encephalomyelitis (2009) (41)
Site‐specific anti‐tumor immunity: Differences in DC function, TGF‐β production and numbers of intratumoral Foxp3+ Treg (2009) (40)
Murine Glia Cells in Culture Can be Stimulated to Generate Reactive Oxygen (1987) (40)
Ex vivo malignant glioma cells are sensitive to Fas (CD95/APO-1) ligand-mediated apoptosis (1998) (39)
CENTRAL-NERVOUS-SYSTEM INVOLVEMENT IN EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS (1977) (39)
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis. (1997) (39)
THE ROLE OF ASTROCYTES IN THE INTERACTION BETWEEN THE IMMUNE AND NERVOUS SYSTEM (1986) (38)
FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors (1998) (38)
Production of nitrite by primary rat astrocytes in response to pneumococci (1995) (35)
Intracerebral Synthesis of Tumor Necrosis Factor‐α and Interleukin‐6 in Infectious Meningitis a (1990) (35)
T cell apoptosis induced by interleukin-2 deprivation or transforming growth factor-beta 2: modulation by the phosphatase inhibitors okadaic acid and calyculin A. (1995) (35)
CD95 (Fas/APO-1) antibody-mediated apoptosis of human retinal pigment epithelial cells. (1995) (33)
Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells. (1997) (32)
Brain tumors: detection of B-cell stimulatory factor-2/interleukin-6 in the absence of oligoclonal bands of immonoglobulins (1989) (32)
Role of Lymphotoxin in Experimental Models of Infectious Diseases: Potential Benefits and Risks of a Therapeutic Inhibition of the Lymphotoxin-β Receptor Pathway (2005) (31)
Interferon-γ antagonizes transforming growth factor-β 2-mediated immunosuppression in murine Toxoplasma encephalitis (1998) (31)
CXCL11 is involved in leucocyte recruitment to the central nervous system in neuroborreliosis (2005) (31)
Sequence analysis of the promoter region of the glioblastoma derived T cell suppressor factor / transforming growth factor (TGF)-β2 gene reveals striking differences to the TGF-β1 and -β3 genes (1990) (31)
Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase. (1999) (31)
Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon (1991) (30)
Human small cell lung cancer expresses the octamer DNA-binding and nervous system-specific transcription factor N-Oct 3 (brain-2). (1992) (29)
Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice (2016) (29)
Isolation of the human genomic brain-2/N-Oct 3 gene (POUF3) and assignment to chromosome 6q16. (1995) (29)
Immune-mediated injury in bacterial meningitis. (1993) (28)
Role of IκBα and IκBβ in the biphasic nuclear translocation of NF‐κB in TNFα‐stimulated astrocytes and in neuroblastoma cells (1999) (27)
Macrophages in the Brain: Friends or Enemies? (1994) (26)
Tumor Necrosis Factor and Transforming Growth Factor β Regulate Clock Genes by Controlling the Expression of the Cold Inducible RNA-binding Protein (CIRBP)* (2013) (25)
Immunoregulatory Factors Secreted by Astrocytes and Glioblastoma Cells (1987) (25)
Therapeutic effect of transforming growth factor-beta 2 on actively induced EAN but not adoptive transfer EAN. (1994) (25)
Primary brain tumors differ in their expression of octamer deoxyribonucleic acid-binding transcription factors from long-term cultured glioma cell lines. (1994) (25)
CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway (2015) (25)
Protective effect of a 21-aminosteroid during experimental pneumococcal meningitis. (1995) (24)
Astrocytes and lymphocytes: Intercellular communication by growth factors (1982) (23)
Bacterial Meningitis: The Role of Transforming Growth Factor-Beta in Innate Immunity and Secondary Brain Damage (2007) (23)
Identification of a SIRT 1 Mutation in a Family with Type 1 Diabetes (2013) (22)
Foetal loss, liver necrosis and acute lupus erythematosus in a patient with antiphospholipid antibody syndrome (2001) (22)
Transforming growth factor‐beta inhibits the expression of clock genes (2012) (22)
Fas ligand gene transfer combined with low dose cyclosporine A reduces acute lung allograft rejection (2000) (20)
Activation of human platelet-derived latent transforming growth factor-beta 1 by human glioblastoma cells. Comparison with proteolytic and glycosidic enzymes. (1991) (20)
Superantigen overcomes resistance of IL-6-deficient mice towards MOG-induced EAE by a TNFR1 controlled pathway. (2001) (20)
Production of B Cell Stimulatory Factor-2 and Interferon Y in the Central Nervous System during Viral Meningitis and Encephalitis Evaluation in a Murine Model Infection and in Patients Brief Definitive Report (1988) (20)
Monoclonal gammopathy in chronic active hepatitis. (2008) (20)
TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte‐derived dendritic cells (2016) (20)
Fas/Apo-1 (CD95)-mediated apoptosis of neutrophils with Fas ligand (CD95L)-expressing tumors is crucial for induction of inflammation by neutrophilic polymorphonuclear leukocytes associated with antitumor immunity. (2001) (19)
Cytokine-induced sleep: Neurons respond to TNF with production of chemokines and increased expression of Homer1a in vitro (2015) (18)
Maturation‐dependent Modulation of Apoptosis in Cultured Cerebellar Granule Neurons by Cytokines and Neurotrophins (1996) (18)
TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulation (2011) (18)
Involvement of the N‐methyl‐D‐aspartate receptor in neuronal cell death induced by cytotoxic T cell‐derived secretory granules (1999) (17)
The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X Chromosomes (1994) (16)
Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics (1997) (15)
Transforming growth factor-beta (TGF-beta)-resistant helper T lymphocyte clones show a concomitant loss of all three types of TGF-beta receptors. (1991) (15)
Production and function of IL-10 in the central nervous system. (1994) (14)
On the role of astrocytes in polyclonal T cell activation (1986) (14)
Antigen presentation in the CNS (1997) (13)
Glia cell response to bacterial lipopolysaccharide Effect on nucleotide synthesis, its genetic control and definition of the active principle (1981) (13)
Treatment of inclusion body myositis: is low-dose intravenous immunoglobulin the solution? (2012) (13)
Interferon-gamma antagonizes transforming growth factor-beta2-mediated immunosuppression in murine Toxoplasma encephalitis. (1998) (12)
CD 95 expression in traumatic proliferative vitreoretinopathy: a target for the induction of apoptosis. (1996) (12)
N-Oct 5 is generated by in vitro proteolysis of the neural POU-domain protein N-Oct 3 (1997) (11)
Superantigen overcomes resistance of IL‐6‐deficient mice towards MOG‐induced EAE by a TNFR1 controlled pathway (2001) (11)
Mitogen-activated lymphocytes of normals and glioma patients produce factors with anti-glioblastoma activity in vitro (1986) (10)
Microglia and tumor rejection. (1994) (10)
[Antibodies against nicotine-like acetylcholine receptors of central nervous system and muscles in epileptics with IgA deficiency]. (1978) (10)
NG 2 expressed by macrophages and oligodendrocyte precursor cells is dispensable in experimental autoimmune encephalomyelitis (2011) (10)
Role of IkappaBalpha and IkappaBbeta in the biphasic nuclear translocation of NF-kappaB in TNFalpha-stimulated astrocytes and in neuroblastoma cells. (1999) (9)
CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis (2013) (9)
Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10 (2015) (9)
The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart. (1993) (9)
Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study (2017) (8)
Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor (2020) (7)
Involvement of cyclic AMP in the regulations of lymphokine induced glia cell stimulation. (1981) (7)
Lymphokines and the brain (2004) (7)
The endothelium — Astrocyte immune control system of the brain (2004) (7)
Sequence analysis of the promoter region of the glioblastoma derived T cell suppressor factor/transforming growth factor (TGF)-beta 2 gene reveals striking differences to the TGF-beta 1 and -beta 3 genes. (1990) (7)
Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes (2015) (6)
Antibodies against muscle and brain nicotinic acetylcholine receptors in IgA-deficient patients with epilepsy. (1979) (6)
TNF induced inhibition of Cirbp expression depends on RelB NF-κB signalling pathway (2015) (5)
Accessory Cells and the Activation and Expression of Different T Cell Functions (1986) (5)
Immune response to brain tumors (1992) (5)
Tumournecrosis factor-u ininfectious meningitis (1989) (5)
Interleukin 1 and the brain (1984) (4)
Inhibition of meningitis‐associated neutrophil apoptosis by TNF‐α depends on functional PI3‐kinase in monocytes (2013) (4)
HSV-1-based amplicon particles are able to transduce cells of feline origin with genes encoding biologically functional feline IL-10 or IL-6. (2002) (3)
Production of cytokines in the central nervous system (1991) (3)
Neuroinflammatory TNF a Impairs Memory via Astrocyte Signaling Graphical (3)
Intracerebral synthesis of tumor necrosis factor-alpha and interleukin-6 in infectious meningitis. (1990) (3)
METABOLISM OF PTERINS IN THE CELLULAR IMMUNE SYSTEM OF MAN AND MOUSE (1987) (3)
On the production of immunoglobulins in the central nervous system: an involvement of B cell stimulatory factor 2/interleukin 6 produced intrathecally? (1989) (2)
Experimental autoimmune encephalitis in cytokine gene knockout mice (1998) (2)
On the Intrathecal Synthesis of Immunoglobulins: Detection of BSF-2/IL-6 in CSF (1990) (2)
Production of prostaglandin E and IL-I like factors by cultured astrocytes and C6 glioma cells (1983) (2)
An Immunological Function for Astrocytes (1986) (2)
Astrocytes and microglial cells: immune regulatory cells of the central nervous system (1992) (2)
Immunoregulation in the Central Nervous System: Detection of Cytokines in Cerebrospinal Fluid (1990) (1)
Glioblastoma‐Cell‐Derived T‐Cell Suppressor Factor (G‐TsF) Sequence Analysis and Biologic Mechanism of G‐TsF (1988) (1)
Viral interactions with receptors in the central nervous system and on lymphocytes. (1983) (1)
Receptor Deficiency Affects Sleep and the Sleep EEG Tumor Necrosis Factor (TNF) Ligand and TNF (2015) (0)
Astrocytes secrete transforming growth factor (TGF)-β2 (in latent form) but not TGF-β1 or β2 (1993) (0)
Regulation of expression of TGF-beta 2 in the nervous system. (1991) (0)
Cytokine studies in Behcet's disease (1991) (0)
Narcolepsy: Autoimmunity or Secondary to Infection? (2011) (0)
Differential Expression of the Genes for Transforming Growth Factor‐β and β2 in Human Tumor Cells a (1990) (0)
The controversial platform technique for REM sleep deprivation in rats (0)
2127 FAS/APO-1 mediated apoptosis in retinal pigment epithelial cells, modulation by cytokines (1995) (0)
Requirement for antigen processing and influence of invariant chain and H-2M deficiencies on T-Cell activation in autoimmune encephalomyelitis (2001) (0)
Cystine/glutamate antiporter system Xc- deficiency impairs insulin secretion (2023) (0)
Listeria Meningitis: Identification of a Cerebrospinal Fluid Inhibitor of Macrophage Listericidal Function as Interleukln 10 By Karl Frei,* David Nadal,~ Hans-Walter Pfister, S and (1993) (0)
Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor (2020) (0)
Influence of invariant chain and H-2M deficiencies in antigen processing and T cell activation in autoimmune encephalomyelitis. (2000) (0)
Infections: Meningitis and Encephalitis (2002) (0)
Leukocyte Recruitment into the Central HIV Type 1 Nef Protein Is a Viral Factor for (1999) (0)
Can astrocytes and C6 glial cells substitute for macrophages by their production of IL-1?☆☆☆ (1982) (0)
The glioblastoma cell derived T cell suppressor factor (G-TsF): Sequence analysis and biological mechanism of G-TsF (1987) (0)
Production of chemotactic factors in infectious diseases of the nervous system (1995) (0)
Tumor necrosis factor ligand and receptor deficiency affects sleep in mice (2001) (0)
Neuroblastoma Neuro-2 a Cells Fas / APO-1 Ligand ( CD 95 L )-Transfected Induction of Antitumor Immunity with (1999) (0)
Narcolepsy: Autoimmunity or Secondary to Infection? Tnf and Its Receptors: Essential in the Pathogenesis of Narcolepsy? (2011) (0)
Site-specific anti-tumor immunity : differences in DC function , TGF-production and numbers of intratumoral Foxp 3 + regulatory T cells (2009) (0)
Not only glioblastoma cells but also untransformed glia cells express transforming growth factor beta. (1993) (0)
[The activation of T-lymphocytes in the central nervous system]. (1986) (0)

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