Adriano Fontana
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Swiss immunologist
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Biology
Adriano Fontana's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Adriano Fontana's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape (1996) (1354)
- RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation (2011) (1096)
- Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity (1998) (838)
- Astrocytes present myelin basic protein to encephalitogenic T-cell lines (1984) (776)
- Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. (1982) (735)
- On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases (1989) (699)
- Increased Number of Islet-Associated Macrophages in Type 2 Diabetes (2007) (684)
- Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells (1987) (619)
- [Interleukin 1]. (1985) (571)
- Prevention of Islet Allograft Rejection with Engineered Myoblasts Expressing FasL in Mice (1996) (483)
- Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate (1991) (438)
- Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. (1985) (435)
- Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2. (1989) (402)
- Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. (2001) (400)
- Complementary DNA for human glioblastoma‐derived T cell suppressor factor, a novel member of the transforming growth factor‐beta gene family. (1987) (394)
- Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines. (1994) (376)
- Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia. (1992) (370)
- Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects. (1984) (361)
- The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis (1995) (360)
- T cell suppressor factor from human glioblastoma cells is a 12.5‐kd protein closely related to transforming growth factor‐beta. (1987) (344)
- Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). (1999) (320)
- IL‐6‐deficient mice resist myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis (1998) (315)
- TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription (2007) (313)
- Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction? (1984) (274)
- Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid (1989) (273)
- Macrophage‐induced cytotoxicity of N‐methyl‐D‐aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines (1992) (271)
- Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. (1995) (271)
- Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons. (1994) (269)
- Mini‐review: Specificity and expression of CIITA, the master regulator of MHC class II genes (2004) (268)
- The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-β, T-cell apoptosis, and the immune privilege of the brain (1995) (267)
- The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. (2005) (263)
- Production of hemopoietic colony-stimulating factors by astrocytes. (1990) (252)
- Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients (1988) (248)
- Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients (1988) (231)
- Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling (2015) (227)
- Severity of symptoms and demyelination in MOG‐induced EAE depends on TNFR1 (1999) (212)
- Local Fas/APO‐1 (CD95) ligand‐mediated tumor cell killing in vivo (1995) (208)
- Astrocyte-derived interleukin 3 as a growth factor for microglia cells and peritoneal macrophages. (1986) (200)
- Mesenteric lymph nodes are critical for the induction of high‐dose oral tolerance in the absence of Peyer's patches (2002) (197)
- Tumor Necrosis Factor α and Lymphotoxin α Are Not Required for Induction of Acute Experimental Autoimmune Encephalomyelitis (1997) (195)
- The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release (2011) (194)
- TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. (2000) (193)
- TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription. (2007) (185)
- Maturation of Dendritic Cells Is Accompanied by Rapid Transcriptional Silencing of Class II Transactivator (Ciita) Expression (2001) (183)
- Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis? (1990) (180)
- Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. (1987) (178)
- Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. (1994) (173)
- Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. (1999) (171)
- Astrocytes of the brain synthesize interleukin 3-like factors. (1985) (170)
- C-X-C and C-C chemokines are expressed in the cerebrospinal fluid in bacterial meningitis and mediate chemotactic activity on peripheral blood-derived polymorphonuclear and mononuclear cells in vitro. (1997) (166)
- Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-γ inducible protein 10 (1999) (166)
- Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis (1998) (163)
- Immune‐Mediated Encephalitis: On the Role of Antigen‐Presenting Cells in Brain Tissue (1987) (162)
- FLIP switches Fas-mediated glucose signaling in human pancreatic β cells from apoptosis to cell replication (2002) (157)
- Experimental pneumococcal meningitis: Cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide (1995) (155)
- Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. (1992) (155)
- TNF‐α and IFN‐γ render microglia sensitive to Fas ligand‐induced apoptosis by induction of Fas expression and down‐regulation of Bcl‐2 and Bcl‐xL (1998) (153)
- Chemokines and chemotaxis of leukocytes in infectious meningitis (1998) (152)
- Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches (2001) (152)
- Puromycin-sensitive Aminopeptidase (1995) (151)
- Interleukin-1 derived from astrocytes enhances slow wave activity in sleep EEG of the rat. (1984) (151)
- Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. (1990) (151)
- Modulation of the immune response by transforming growth factor beta. (1992) (147)
- MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity (2010) (146)
- Interleukin-6–Deficient Mice Resist Development of Autoimmune Myocarditis Associated With Impaired Upregulation of Complement C3 (2003) (146)
- Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis. (1987) (145)
- Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice. (1989) (143)
- Selective Abrogation of Major Histocompatibility Complex Class II Expression on Extrahematopoietic Cells in Mice Lacking Promoter IV of the Class II Transactivator Gene (2001) (141)
- Lack of IL-6 augments inflammatory response but decreases vascular permeability in bacterial meningitis. (2003) (139)
- The glioblastoma‐derived T‐cell suppressor factor/transforming growth factor beta2 inhibits the generation of lymphokineactivated killer (LAK) cells (1988) (133)
- Fas/APO-1 gene transfer for human malignant glioma. (1995) (132)
- Astrocyte-derived TGF-beta 2 and NGF differentially regulate neural recognition molecule expression by cultured astrocytes (1991) (132)
- Transforming growth factor‐β2 induces apoptosis of murine T cell clones without down‐regulating bcl‐2 mRNA expression (1994) (125)
- Interleukin-6 is elevated in plasma in multiple sclerosis (1991) (125)
- The glioblastoma‐derived t cell suppressor factor/ transforming growth factor‐β2 inhibits t cell growth without affecting the interaction of interleukin 2 with its receptor (1988) (123)
- Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon‐γ inducible protein‐10 and monocyte chemotactic protein‐1 (1997) (123)
- Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse. (1987) (122)
- Role of ninjurin‐1 in the migration of myeloid cells to central nervous system inflammatory lesions (2011) (122)
- Myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas‐ and Fas ligand‐deficient lpr and gld mice (1997) (121)
- The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation (2003) (120)
- Interleukin‐16, produced by synovial fibroblasts, mediates chemoattraction for CD4+ T lymphocytes in rheumatoid arthritis (1998) (120)
- TGFβ directs gene expression of activated microglia to an anti‐inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes (2003) (119)
- Listeria meningitis: identification of a cerebrospinal fluid inhibitor of macrophage listericidal function as interleukin 10 (1993) (117)
- Matrix metalloproteinases and tissue inhibitors of metalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid (1998) (116)
- Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity. (1999) (108)
- Experimental Listeria meningoencephalitis. Macrophage inflammatory protein-1 alpha and -2 are produced intrathecally and mediate chemotactic activity in cerebrospinal fluid of infected mice. (1995) (107)
- Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity. (2001) (106)
- Hepatocyte-derived interleukin-6 and tumor-necrosis factor alpha mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes. (1995) (106)
- TGF‐β‐treated microglia induce oligodendrocyte precursor cell chemotaxis through the HGF‐c‐Met pathway (2005) (105)
- Identification of a SIRT1 mutation in a family with type 1 diabetes. (2013) (102)
- Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumococcal meningitis. (1996) (99)
- Cancer cell sensitization to Fas-mediated apoptosis by sodium butyrate (1998) (97)
- Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? (2010) (93)
- Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency (2010) (93)
- Induction of antitumor immunity with Fas/APO-1 ligand (CD95L)-transfected neuroblastoma neuro-2a cells. (1999) (92)
- Production of macrophage colony-stimulating factor by astrocytes and brain macrophages (1992) (91)
- Endothelial Cell Barrier Impairment Induced by Glioblastomas and Transforming Growth Factor &bgr;2 Involves Matrix Metalloproteinases and Tight Junction Proteins (2008) (91)
- Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection. (2000) (90)
- Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis (2000) (89)
- The Endothelin System in Human Glioblastoma (2000) (88)
- Protease inhibitors interfere with the transforming growth factor-beta-dependent but not the transforming growth factor-beta-independent pathway of tumor cell-mediated immunosuppression. (1992) (88)
- Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor (1993) (86)
- Mechanisms of brain injury in bacterial meningitis: workshop summary. (1994) (85)
- Clock Gene Modulation by TNF-α Depends on Calcium and p38 MAP Kinase Signaling (2009) (85)
- Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia (1990) (84)
- Topoisomerase‐I inhibitors for human malignant glioma: Differential modulation of p53, p21, bax and bcl‐2 expression and of CD95‐mediated apoptosis by camptothecin and β‐lapachone (1997) (83)
- Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand. (1999) (83)
- Meningitis-Associated Central Nervous System Complications are Mediated by the Activation of Poly(ADP-ribose) Polymerase (2002) (82)
- Role of Caspase‐1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase‐1‐deficient mice (2002) (82)
- TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis. (1997) (81)
- TGF-β-Induced Apoptosis of Cerebellar Granule Neurons Is Prevented by Depolarization (1996) (81)
- Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. (1999) (81)
- cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. (1993) (80)
- Cytokine networks in multiple sclerosis: lost in translation (2010) (79)
- TGF‐β induces the expression of the FLICE‐inhibitory protein and inhibits Fas‐mediated apoptosis of microglia (2000) (78)
- Transient Production of TGF‐β2 by Postnatal Cerebellar Neurons and its Effect on Neuroblast Proliferation (1994) (74)
- In vitro stimulation of glia cells by a lymphocyteproduced factor (1980) (73)
- Induction of colitis in mice deficient of Peyer's patches and mesenteric lymph nodes is associated with increased disease severity and formation of colonic lymphoid patches. (2002) (73)
- Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO‐1/CD95) pathway (1996) (72)
- Biological and biochemical characterization of an interleukin 1‐like factor from rat C6 glioma cells (1983) (71)
- Human immunodeficiency virus type-1 Nef protein induces blood–brain barrier disruption in the rat: role of matrix metalloproteinase-9 (2000) (68)
- HIV type 1 Nef protein is a viral factor for leukocyte recruitment into the central nervous system. (1999) (68)
- Transforming growth factor beta 2 inhibits cerebrovascular changes and brain edema formation in the tumor necrosis factor alpha-independent early phase of experimental pneumococcal meningitis (1992) (66)
- Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblastoma cells. Despite the presence of inducing signals GM-CSF is not expressed in vivo. (1992) (66)
- Tumour necrosis factor-alpha in infectious meningitis. (1989) (66)
- Apoptosis in proliferative vitreoretinal disorders: possible involvement of TGF-beta-induced RPE cell apoptosis. (1997) (66)
- Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-γ (1986) (66)
- TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. (1998) (65)
- Cloning of the Human Puromycin‐Sensitive Aminopeptidase and Evidence for Expression in Neurons (1997) (65)
- Immunobiology of Microglial Cells a (1988) (65)
- Variations in anticipatory cognitive stress appraisal and differential proinflammatory cytokine expression in response to acute stress (2007) (64)
- Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis. (1995) (63)
- Cell type-specific regulation of expression of transcription factor AP-2 in neuroectodermal cells. (1994) (63)
- Glia cell stimulating factor (GSF): A new lymphokine Part 1. Cellular sources and partial purification of murine GSF, role of cytoskeleton and protein synthesis in its production (1982) (62)
- Transforming growth factor-beta modulates T cell-mediated encephalitis caused by Borna disease virus. Pathogenic importance of CD8+ cells and suppression of antibody formation. (1991) (60)
- Effects of interferons and hydrogen peroxide on CA3 pyramidal cells in rat hippocampal slice cultures (1993) (59)
- Depression in Autoimmune Diseases. (2016) (59)
- Tumor necrosis factor (TNF) ligand and TNF receptor deficiency affects sleep and the sleep EEG. (2002) (57)
- Partial purification and biochemical characterization of a T cell suppressor factor produced by human glioblastoma cells. (1985) (57)
- Astrocytes and Microglia Produce Interleukin‐12 p40 a (1996) (56)
- Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease. (1990) (56)
- Inhibition of IL-1β Improves Fatigue in Type 2 Diabetes (2011) (54)
- Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels (1988) (53)
- Neurons and neuroblastoma as a source of macrophage colony‐stimulating factor (1992) (49)
- REVIEW ■ : Activation of Microglia: A Dangerous Interlude in Immune Function in the Brain (1996) (49)
- TGFbeta receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis. (2006) (48)
- Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation. (2010) (45)
- Human glioblastoma cell derived transforming growth factor-β2: evidence for secretion of both high and low molecular weight biologically active forms (1991) (44)
- Interaction of reovirus with cell surface receptors. II. Generation of suppressor T cells by the hemagglutinin of reovirus type 3. (1980) (44)
- NG2 expressed by macrophages and oligodendrocyte precursor cells is dispensable in experimental autoimmune encephalomyelitis. (2011) (43)
- Expression of TGF-beta 2 in human glioblastoma: a role in resistance to immune rejection? (1991) (43)
- Glia cell stimulating factor (GSF): A new lymphokine Part 2. Cellular sources and partial purification of human GSF (1982) (41)
- Immunological Aspects of Epilepsy (1980) (41)
- Expression of the HGF receptor c‐met by macrophages in experimental autoimmune encephalomyelitis (2009) (41)
- Site‐specific anti‐tumor immunity: Differences in DC function, TGF‐β production and numbers of intratumoral Foxp3+ Treg (2009) (40)
- Murine Glia Cells in Culture Can be Stimulated to Generate Reactive Oxygen (1987) (40)
- Ex vivo malignant glioma cells are sensitive to Fas (CD95/APO-1) ligand-mediated apoptosis (1998) (39)
- CENTRAL-NERVOUS-SYSTEM INVOLVEMENT IN EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS (1977) (39)
- Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis. (1997) (39)
- THE ROLE OF ASTROCYTES IN THE INTERACTION BETWEEN THE IMMUNE AND NERVOUS SYSTEM (1986) (38)
- FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors (1998) (38)
- Production of nitrite by primary rat astrocytes in response to pneumococci (1995) (35)
- Intracerebral Synthesis of Tumor Necrosis Factor‐α and Interleukin‐6 in Infectious Meningitis a (1990) (35)
- T cell apoptosis induced by interleukin-2 deprivation or transforming growth factor-beta 2: modulation by the phosphatase inhibitors okadaic acid and calyculin A. (1995) (35)
- CD95 (Fas/APO-1) antibody-mediated apoptosis of human retinal pigment epithelial cells. (1995) (33)
- Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells. (1997) (32)
- Brain tumors: detection of B-cell stimulatory factor-2/interleukin-6 in the absence of oligoclonal bands of immonoglobulins (1989) (32)
- Role of Lymphotoxin in Experimental Models of Infectious Diseases: Potential Benefits and Risks of a Therapeutic Inhibition of the Lymphotoxin-β Receptor Pathway (2005) (31)
- Interferon-γ antagonizes transforming growth factor-β 2-mediated immunosuppression in murine Toxoplasma encephalitis (1998) (31)
- CXCL11 is involved in leucocyte recruitment to the central nervous system in neuroborreliosis (2005) (31)
- Sequence analysis of the promoter region of the glioblastoma derived T cell suppressor factor / transforming growth factor (TGF)-β2 gene reveals striking differences to the TGF-β1 and -β3 genes (1990) (31)
- Cloning and analysis of the gene for the human puromycin-sensitive aminopeptidase. (1999) (31)
- Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon (1991) (30)
- Human small cell lung cancer expresses the octamer DNA-binding and nervous system-specific transcription factor N-Oct 3 (brain-2). (1992) (29)
- Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice (2016) (29)
- Isolation of the human genomic brain-2/N-Oct 3 gene (POUF3) and assignment to chromosome 6q16. (1995) (29)
- Immune-mediated injury in bacterial meningitis. (1993) (28)
- Role of IκBα and IκBβ in the biphasic nuclear translocation of NF‐κB in TNFα‐stimulated astrocytes and in neuroblastoma cells (1999) (27)
- Macrophages in the Brain: Friends or Enemies? (1994) (26)
- Tumor Necrosis Factor and Transforming Growth Factor β Regulate Clock Genes by Controlling the Expression of the Cold Inducible RNA-binding Protein (CIRBP)* (2013) (25)
- Immunoregulatory Factors Secreted by Astrocytes and Glioblastoma Cells (1987) (25)
- Therapeutic effect of transforming growth factor-beta 2 on actively induced EAN but not adoptive transfer EAN. (1994) (25)
- Primary brain tumors differ in their expression of octamer deoxyribonucleic acid-binding transcription factors from long-term cultured glioma cell lines. (1994) (25)
- CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway (2015) (25)
- Protective effect of a 21-aminosteroid during experimental pneumococcal meningitis. (1995) (24)
- Astrocytes and lymphocytes: Intercellular communication by growth factors (1982) (23)
- Bacterial Meningitis: The Role of Transforming Growth Factor-Beta in Innate Immunity and Secondary Brain Damage (2007) (23)
- Identification of a SIRT 1 Mutation in a Family with Type 1 Diabetes (2013) (22)
- Foetal loss, liver necrosis and acute lupus erythematosus in a patient with antiphospholipid antibody syndrome (2001) (22)
- Transforming growth factor‐beta inhibits the expression of clock genes (2012) (22)
- Fas ligand gene transfer combined with low dose cyclosporine A reduces acute lung allograft rejection (2000) (20)
- Activation of human platelet-derived latent transforming growth factor-beta 1 by human glioblastoma cells. Comparison with proteolytic and glycosidic enzymes. (1991) (20)
- Superantigen overcomes resistance of IL-6-deficient mice towards MOG-induced EAE by a TNFR1 controlled pathway. (2001) (20)
- Production of B Cell Stimulatory Factor-2 and Interferon Y in the Central Nervous System during Viral Meningitis and Encephalitis Evaluation in a Murine Model Infection and in Patients Brief Definitive Report (1988) (20)
- Monoclonal gammopathy in chronic active hepatitis. (2008) (20)
- TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte‐derived dendritic cells (2016) (20)
- Fas/Apo-1 (CD95)-mediated apoptosis of neutrophils with Fas ligand (CD95L)-expressing tumors is crucial for induction of inflammation by neutrophilic polymorphonuclear leukocytes associated with antitumor immunity. (2001) (19)
- Cytokine-induced sleep: Neurons respond to TNF with production of chemokines and increased expression of Homer1a in vitro (2015) (18)
- Maturation‐dependent Modulation of Apoptosis in Cultured Cerebellar Granule Neurons by Cytokines and Neurotrophins (1996) (18)
- TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulation (2011) (18)
- Involvement of the N‐methyl‐D‐aspartate receptor in neuronal cell death induced by cytotoxic T cell‐derived secretory granules (1999) (17)
- The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X Chromosomes (1994) (16)
- Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics (1997) (15)
- Transforming growth factor-beta (TGF-beta)-resistant helper T lymphocyte clones show a concomitant loss of all three types of TGF-beta receptors. (1991) (15)
- Production and function of IL-10 in the central nervous system. (1994) (14)
- On the role of astrocytes in polyclonal T cell activation (1986) (14)
- Antigen presentation in the CNS (1997) (13)
- Glia cell response to bacterial lipopolysaccharide Effect on nucleotide synthesis, its genetic control and definition of the active principle (1981) (13)
- Treatment of inclusion body myositis: is low-dose intravenous immunoglobulin the solution? (2012) (13)
- Interferon-gamma antagonizes transforming growth factor-beta2-mediated immunosuppression in murine Toxoplasma encephalitis. (1998) (12)
- CD 95 expression in traumatic proliferative vitreoretinopathy: a target for the induction of apoptosis. (1996) (12)
- N-Oct 5 is generated by in vitro proteolysis of the neural POU-domain protein N-Oct 3 (1997) (11)
- Superantigen overcomes resistance of IL‐6‐deficient mice towards MOG‐induced EAE by a TNFR1 controlled pathway (2001) (11)
- Mitogen-activated lymphocytes of normals and glioma patients produce factors with anti-glioblastoma activity in vitro (1986) (10)
- Microglia and tumor rejection. (1994) (10)
- [Antibodies against nicotine-like acetylcholine receptors of central nervous system and muscles in epileptics with IgA deficiency]. (1978) (10)
- NG 2 expressed by macrophages and oligodendrocyte precursor cells is dispensable in experimental autoimmune encephalomyelitis (2011) (10)
- Role of IkappaBalpha and IkappaBbeta in the biphasic nuclear translocation of NF-kappaB in TNFalpha-stimulated astrocytes and in neuroblastoma cells. (1999) (9)
- CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis (2013) (9)
- Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10 (2015) (9)
- The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart. (1993) (9)
- Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study (2017) (8)
- Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor (2020) (7)
- Involvement of cyclic AMP in the regulations of lymphokine induced glia cell stimulation. (1981) (7)
- Lymphokines and the brain (2004) (7)
- The endothelium — Astrocyte immune control system of the brain (2004) (7)
- Sequence analysis of the promoter region of the glioblastoma derived T cell suppressor factor/transforming growth factor (TGF)-beta 2 gene reveals striking differences to the TGF-beta 1 and -beta 3 genes. (1990) (7)
- Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes (2015) (6)
- Antibodies against muscle and brain nicotinic acetylcholine receptors in IgA-deficient patients with epilepsy. (1979) (6)
- TNF induced inhibition of Cirbp expression depends on RelB NF-κB signalling pathway (2015) (5)
- Accessory Cells and the Activation and Expression of Different T Cell Functions (1986) (5)
- Immune response to brain tumors (1992) (5)
- Tumournecrosis factor-u ininfectious meningitis (1989) (5)
- Interleukin 1 and the brain (1984) (4)
- Inhibition of meningitis‐associated neutrophil apoptosis by TNF‐α depends on functional PI3‐kinase in monocytes (2013) (4)
- HSV-1-based amplicon particles are able to transduce cells of feline origin with genes encoding biologically functional feline IL-10 or IL-6. (2002) (3)
- Production of cytokines in the central nervous system (1991) (3)
- Neuroinflammatory TNF a Impairs Memory via Astrocyte Signaling Graphical (3)
- Intracerebral synthesis of tumor necrosis factor-alpha and interleukin-6 in infectious meningitis. (1990) (3)
- METABOLISM OF PTERINS IN THE CELLULAR IMMUNE SYSTEM OF MAN AND MOUSE (1987) (3)
- On the production of immunoglobulins in the central nervous system: an involvement of B cell stimulatory factor 2/interleukin 6 produced intrathecally? (1989) (2)
- Experimental autoimmune encephalitis in cytokine gene knockout mice (1998) (2)
- On the Intrathecal Synthesis of Immunoglobulins: Detection of BSF-2/IL-6 in CSF (1990) (2)
- Production of prostaglandin E and IL-I like factors by cultured astrocytes and C6 glioma cells (1983) (2)
- An Immunological Function for Astrocytes (1986) (2)
- Astrocytes and microglial cells: immune regulatory cells of the central nervous system (1992) (2)
- Immunoregulation in the Central Nervous System: Detection of Cytokines in Cerebrospinal Fluid (1990) (1)
- Glioblastoma‐Cell‐Derived T‐Cell Suppressor Factor (G‐TsF) Sequence Analysis and Biologic Mechanism of G‐TsF (1988) (1)
- Viral interactions with receptors in the central nervous system and on lymphocytes. (1983) (1)
- Receptor Deficiency Affects Sleep and the Sleep EEG Tumor Necrosis Factor (TNF) Ligand and TNF (2015) (0)
- Astrocytes secrete transforming growth factor (TGF)-β2 (in latent form) but not TGF-β1 or β2 (1993) (0)
- Regulation of expression of TGF-beta 2 in the nervous system. (1991) (0)
- Cytokine studies in Behcet's disease (1991) (0)
- Narcolepsy: Autoimmunity or Secondary to Infection? (2011) (0)
- Differential Expression of the Genes for Transforming Growth Factor‐β and β2 in Human Tumor Cells a (1990) (0)
- The controversial platform technique for REM sleep deprivation in rats (0)
- 2127 FAS/APO-1 mediated apoptosis in retinal pigment epithelial cells, modulation by cytokines (1995) (0)
- Requirement for antigen processing and influence of invariant chain and H-2M deficiencies on T-Cell activation in autoimmune encephalomyelitis (2001) (0)
- Cystine/glutamate antiporter system Xc- deficiency impairs insulin secretion (2023) (0)
- Listeria Meningitis: Identification of a Cerebrospinal Fluid Inhibitor of Macrophage Listericidal Function as Interleukln 10 By Karl Frei,* David Nadal,~ Hans-Walter Pfister, S and (1993) (0)
- Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor (2020) (0)
- Influence of invariant chain and H-2M deficiencies in antigen processing and T cell activation in autoimmune encephalomyelitis. (2000) (0)
- Infections: Meningitis and Encephalitis (2002) (0)
- Leukocyte Recruitment into the Central HIV Type 1 Nef Protein Is a Viral Factor for (1999) (0)
- Can astrocytes and C6 glial cells substitute for macrophages by their production of IL-1?☆☆☆ (1982) (0)
- The glioblastoma cell derived T cell suppressor factor (G-TsF): Sequence analysis and biological mechanism of G-TsF (1987) (0)
- Production of chemotactic factors in infectious diseases of the nervous system (1995) (0)
- Tumor necrosis factor ligand and receptor deficiency affects sleep in mice (2001) (0)
- Neuroblastoma Neuro-2 a Cells Fas / APO-1 Ligand ( CD 95 L )-Transfected Induction of Antitumor Immunity with (1999) (0)
- Narcolepsy: Autoimmunity or Secondary to Infection? Tnf and Its Receptors: Essential in the Pathogenesis of Narcolepsy? (2011) (0)
- Site-specific anti-tumor immunity : differences in DC function , TGF-production and numbers of intratumoral Foxp 3 + regulatory T cells (2009) (0)
- Not only glioblastoma cells but also untransformed glia cells express transforming growth factor beta. (1993) (0)
- [The activation of T-lymphocytes in the central nervous system]. (1986) (0)
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