Agata Smogorzewska
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Polish-born scientist
Agata Smogorzewska's AcademicInfluence.com Rankings
Agata Smogorzewskabiology Degrees
Biology
#6007
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#8621
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Cell Biology
#791
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#809
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Molecular Biology
#1709
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#1738
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Biochemistry
#1968
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#2109
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Biology
Agata Smogorzewska's Degrees
- PhD Molecular Biology Rockefeller University
Why Is Agata Smogorzewska Influential?
(Suggest an Edit or Addition)According to Wikipedia, Agata Smogorzewska is a Polish-born scientist. She is an associate professor at Rockefeller University, heading the Laboratory of Genome Maintenance. Her work primarily focuses on DNA interstrand crosslink repair and the diseases resulting from deficiencies in this repair pathway, including Fanconi anemia and karyomegalic interstitial nephritis.
Agata Smogorzewska's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage (2007) (3001)
- TRF2 Protects Human Telomeres from End-to-End Fusions (1998) (1727)
- DNA Damage Foci at Dysfunctional Telomeres (2003) (1404)
- Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2 (1997) (950)
- Regulation of telomerase by telomeric proteins. (2004) (842)
- Senescence Induced by Altered Telomere State, Not Telomere Loss (2002) (808)
- Control of Human Telomere Length by TRF1 and TRF2 (2000) (799)
- Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response (2007) (706)
- Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair (2007) (688)
- Homologous Recombination Generates T-Loop-Sized Deletions at Human Telomeres (2004) (542)
- Fanconi anaemia and the repair of Watson and Crick DNA crosslinks (2013) (528)
- Different telomere damage signaling pathways in human and mouse cells (2002) (503)
- The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair (2009) (500)
- Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair (2009) (464)
- Cancer Proliferation Gene Discovery Through Functional Genomics (2008) (396)
- DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2 (2002) (392)
- A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA damage response (2012) (355)
- Mutations of the SLX4 gene in Fanconi anemia (2011) (345)
- A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. (2010) (344)
- Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling (2012) (341)
- Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response. (2015) (256)
- Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. (2012) (249)
- FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway (2008) (242)
- A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination. (2015) (235)
- FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair (2012) (197)
- Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. (2013) (171)
- Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence (2010) (163)
- Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway (2011) (151)
- SnapShot: Fanconi Anemia and Associated Proteins (2015) (149)
- Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions. (2013) (131)
- Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia. (2015) (124)
- Advances in understanding DNA processing and protection at stalled replication forks (2019) (102)
- Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency (2017) (87)
- Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia. (2013) (85)
- Chromosome instability syndromes (2018) (77)
- Natural history and management of Fanconi anemia patients with head and neck cancer: A 10‐year follow‐up (2016) (75)
- Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance. (2015) (70)
- Paraprotein interference in automated chemistry analyzers. (2004) (63)
- Ubiquitylation and the Fanconi anemia pathway (2011) (59)
- Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 (2014) (58)
- Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication (2020) (48)
- Postoperative clinical radiosensitivity in patients with fanconi anemia and head and neck squamous cell carcinoma. (2011) (47)
- Effect of fondaparinux on coagulation assays: results of College of American Pathologists proficiency testing. (2006) (40)
- Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction (2016) (39)
- Comprehensive Analysis of Pathogenic Deletion Variants in Fanconi Anemia Genes (2014) (36)
- S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. (2017) (36)
- Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity. (2018) (34)
- Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links (2019) (34)
- Assessment of SLX4 Mutations in Hereditary Breast Cancers (2013) (33)
- Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype (2017) (30)
- A comprehensive approach to identification of pathogenic FANCA variants in Fanconi anemia patients and their families (2018) (30)
- CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy (2020) (25)
- Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program (2017) (24)
- Postmortem Urine Immunoassay Showing False-Positive Phencyclidine Reactivity in a Case of Fatal Tramadol Overdose (2006) (20)
- THE ROCKEFELLER UNIVERSITY (1965) (18)
- Association of clinical severity with FANCB variant type in Fanconi anemia. (2020) (18)
- Mechanisms of direct replication restart at stressed replisomes. (2020) (11)
- Treatment of Fanconi Anemia–Associated Head and Neck Cancer: Opportunities to Improve Outcomes (2021) (11)
- A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India (2020) (11)
- Fanconi Anemia Pathway Deficiency Drives Copy Number Variation in Squamous Cell Carcinomas (2021) (10)
- Transcriptional silencing of ALDH2 confers a dependency on Fanconi anemia proteins in acute myeloid leukemia. (2021) (8)
- Fanconi Anemia: A Paradigm for Understanding DNA Repair During Replication. (2019) (8)
- Paternal or Maternal Uniparental Disomy of Chromosome 16 Resulting in Homozygosity of a Mutant Allele Causes Fanconi Anemia (2016) (7)
- Esophageal cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant (2020) (7)
- Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells (2017) (6)
- Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. (2022) (6)
- Endogenous formaldehyde destroys blood stem cells. (2021) (6)
- Comparison of the clinical phenotype and haematological course of siblings with Fanconi anaemia (2020) (6)
- New editorial board members (2018) (5)
- The structure-specific endonuclease complex SLX4–XPF regulates Tus–Ter-induced homologous recombination (2021) (4)
- Effect of fondaparinux on coagulation assays (2006) (4)
- Transfusion medicine illustrated. Volume-reduced apheresis platelets. (2005) (4)
- Volume‐reduced apheresis platelets (2005) (4)
- A Dominant Mutation in Hu man RAD 51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination Graphical (2015) (3)
- Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. (2022) (3)
- Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins (2020) (2)
- A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype (2020) (2)
- ALDH9A1 Deficiency as a Source of Endogenous DNA Damage that Requires Repair by the Fanconi Anemia Pathway (2022) (1)
- Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program (2021) (1)
- Clinical severity in Fanconi anemia correlates with residual function of FANCB missense variants (2019) (1)
- Functional Analysis of the Human Telomeric Protein TRF2 (2001) (1)
- Abstract A27: Assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins (2017) (1)
- Sion Paraprotein Interference in Automated Chemistry Ana- Lyzers (0)
- Explorer FAN 1 mutations cause karyomegalic interstitial nephritis , linking chronic kidney failure to defective DNA damage repair (2017) (0)
- Afoundervariant in theSouthAsianpopulation leads toahigh prevalence of FANCL Fanconi anemia cases in India (2019) (0)
- Abstract SY33-01: Mechanism of tumor suppression by the Fanconi anemia proteins (2014) (0)
- Corrigendum: Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. (2017) (0)
- Identification of the nonsense SLX4 variant and evaluation of pathogenicity of the SLX4 variants by complementation assay. (2013) (0)
- Molecular Mechanism Of DNA Interstrand Crosslink Repair (2016) (0)
- RTF2 controls replication repriming and ribonucleotide excision at the replisome (2023) (0)
- Abstract 2600:SLX4mutation in hereditary breast cancer (2012) (0)
- Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource (2022) (0)
- Puck Knipscheer Interstrand Cross-Link Repair The Fanconi Anemia Pathway Promotes Replication-Dependent DNA (2014) (0)
- Functional Genomics Cancer Proliferation Gene Discovery Through (2010) (0)
- Silva , by Multiplex RNAi Screening Profiling Essential Genes in Human Mammary Cells (2009) (0)
- A Novel Source of Endogenous DNA Damage That Requires Repair By the Fanconi Anemia Pathway (2019) (0)
- DDI1 and DDI2‐dependent removal of Replication Termination Factor Domain Containing 1 (RTFDC1) from replication forks is necessary for proper response to replication stress (2017) (0)
- The Loss of ALDH9A1 Is a Significant Source of Endogenous DNA Damage Which May be Reversed By the Inhibition of Polyamine Transport System (2021) (0)
- Dissecting cellular inter‐strand crosslink repair pathways through the recruitment kinetics of Fanconi Anemia (FA) proteins to localized ICLs (2011) (0)
- Abstract A33: A whole genome RNAi screen identifies BRD7 and BAF180 as p53 regulators required for senescence (2011) (0)
- Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication (2020) (0)
- Clinical Severity Correlates with in Vitro Residual Function of FANCB Missense Variants (2018) (0)
- Abstract 6196: Fanconi anemia pathway deficiency drives copy number variation in squamous cell carcinoma (2022) (0)
- Impact of fanconi anemia genotype on outcome after hematopoietic stem cell transplant: A single centre experience of 20 years (2021) (0)
- Abstract B23: The role of bone marrow transplantation in patients with Fanconi anemia and head and neck squamous cell carcinoma receiving radiotherapy: An examination of the International Fanconi Anemia (IFAR) Registry (2020) (0)
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