Alan Chait
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(Suggest an Edit or Addition)Alan Chait's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II) (1993) (4130)
- Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. (1999) (2406)
- Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. (2001) (1629)
- Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. (2007) (926)
- Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis. (1993) (727)
- Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. (1996) (592)
- Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B. (1993) (577)
- Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies (2008) (525)
- Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture. (1984) (505)
- Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells. (1986) (490)
- The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. (1987) (451)
- The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. (2004) (439)
- Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease (2020) (412)
- Triglyceride, high density lipoprotein, and coronary heart disease. (1993) (335)
- Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance (2008) (333)
- Identification of the principal proteoglycan-binding site in LDL. A single-point mutation in apo-B100 severely affects proteoglycan interaction without affecting LDL receptor binding. (1998) (320)
- Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia. (1983) (317)
- Reduced Plasma Peroxyl Radical Trapping Capacity and Increased Susceptibility of LDL to Oxidation In Poorly Controlled IDDM (1994) (314)
- Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins. (1998) (294)
- Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia (1980) (279)
- Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species* (2004) (269)
- Superoxide initiates oxidation of low density lipoprotein by human monocytes. (1987) (264)
- Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. (1994) (257)
- Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. (1989) (249)
- Low-density lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulin-induced stimulation. (1979) (248)
- Thematic review series: The Immune System and Atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease? Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.R400017-JLR200 (2005) (245)
- Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice. (1998) (243)
- Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1 (2012) (237)
- Differential Effect of Saturated and Unsaturated Free Fatty Acids on the Generation of Monocyte Adhesion and Chemotactic Factors by Adipocytes (2009) (231)
- Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions. (2004) (229)
- Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation? (1994) (227)
- Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes. (2002) (224)
- Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanisms. (1993) (221)
- Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis (2013) (220)
- Familial combined hyperlipidemia workshop (1989) (214)
- Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice (2011) (206)
- Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques. (1992) (195)
- Antioxidant Supplements Block the Response of HDL to Simvastatin-Niacin Therapy in Patients With Coronary Artery Disease and Low HDL (2001) (195)
- Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation. (1989) (186)
- Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. (2000) (179)
- Dietary Cholesterol Worsens Adipose Tissue Macrophage Accumulation and Atherosclerosis in Obese LDL Receptor–Deficient Mice (2008) (175)
- Regulatory role of triiodothyronine in the degradation of low density lipoprotein by cultured human skin fibroblasts. (1979) (175)
- Fatty streak expansion and maturation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. (1987) (173)
- Enhanced oxidative susceptibility and reduced antioxidant content of metabolic precursors of small, dense low-density lipoproteins. (2001) (169)
- NADPH Oxidase-derived Reactive Oxygen Species Increases Expression of Monocyte Chemotactic Factor Genes in Cultured Adipocytes* (2012) (168)
- Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and alpha-tocopherol content. (1994) (167)
- Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages. (1997) (160)
- Increase in Serum Amyloid A Evoked by Dietary Cholesterol Is Associated With Increased Atherosclerosis in Mice (2004) (160)
- Proteoglycans Synthesized by Arterial Smooth Muscle Cells in the Presence of Transforming Growth Factor‐&bgr;1 Exhibit Increased Binding to LDLs (2002) (157)
- Adipocyte-Derived Serum Amyloid A3 and Hyaluronan Play a Role in Monocyte Recruitment and Adhesion (2007) (157)
- Lipoprotein lipase secretion by human monocyte-derived macrophages. (1982) (154)
- Bromocriptine treatment of acromegaly. (1975) (154)
- Influence of dietary fat on platelet function in men. (1973) (147)
- Special Report Rationale of the Diet‐Heart Statement of the American Heart Association Report of the Nutrition Committee (1993) (147)
- Platelet-derived growth factor stimulates activity of low density lipoprotein receptors. (1980) (146)
- Hypertriglyceridemia secondary to obesity and diabetes. (2012) (146)
- The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells. (1988) (146)
- In Vivo Stimulation of Low-Density Lipoprotein Degradation by Insulin (1984) (142)
- Reciprocal and Coordinate Regulation of Serum Amyloid A Versus Apolipoprotein A-I and Paraoxonase-1 by Inflammation in Murine Hepatocytes (2006) (141)
- Frequency of risk factors for ischaemic heart-disease in a healthy British population. With particular reference to serum-lipoprotein levels. (1974) (137)
- Modification of low density lipoprotein by lipoprotein lipase or hepatic lipase induces enhanced uptake and cholesterol accumulation in cells. (1988) (135)
- Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease☆ (2002) (134)
- Dietary antioxidants inhibit development of fatty streak lesions in the LDL receptor-deficient mouse. (1998) (130)
- Type III hyperlipoproteinemia: paradoxical hypolipidemic response to estrogen. (1977) (127)
- Safety and tolerability of simvastatin plus niacin in patients with coronary artery disease and low high-density lipoprotein cholesterol (The HDL Atherosclerosis Treatment Study). (2004) (124)
- Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines. (1988) (121)
- Antioxidant vitamin supplementation and lipid peroxidation in smokers. (1998) (115)
- Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the mode of action and on very low density lipoprotein composition. (1974) (113)
- Clinical and metabolic study of alcoholic hyperlipidaemia. (1972) (111)
- Nutritional management of cardiovascular risk factors. A randomized clinical trial. (1997) (110)
- Induction of Glutathione Synthesis in Macrophages by Oxidized Low-Density Lipoproteins Is Mediated by Consensus Antioxidant Response Elements (2003) (108)
- Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL. (2004) (108)
- The influence of oxidatively modified low density lipoproteins on expression of platelet-derived growth factor by human monocyte-derived macrophages. (1991) (108)
- Lipoprotein Lipase Enhances the Binding of Native and Oxidized Low Density Lipoproteins to Versican and Biglycan Synthesized by Cultured Arterial Smooth Muscle Cells* (1999) (107)
- Oxidized Low Density Lipoproteins Regulate Synthesis of Monkey Aortic Smooth Muscle Cell Proteoglycans That Have Enhanced Native Low Density Lipoprotein Binding Properties* (2000) (107)
- Serum Amyloid A and Lipoprotein Retention in Murine Models of Atherosclerosis (2005) (106)
- Serum Lipoprotein Abnormalities in Patients with Ischaemic Heart Disease: Comparisons with a Control Population (1974) (105)
- Köbberling type of familial partial lipodystrophy: an underrecognized syndrome. (2003) (104)
- Cholesterol Feeding Increases C-Reactive Protein and Serum Amyloid A Levels in Lean Insulin-Sensitive Subjects (2005) (103)
- Acquired hyperlipidemia (secondary dyslipoproteinemias). (1990) (103)
- Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. (2007) (102)
- Metabolism of Low-Density Lipoprotein from Patients with Diabetic Hypertriglyceridemia by Cultured Human Skin Fibroblasts (1985) (98)
- Studies of the mechanisms of carbohydrate-induced lipaemia in normal man. (1973) (98)
- Plasma Triglyceride and Fatty Acid Metabolism in Diabetes mellitus (1972) (97)
- Regulatory role of insulin in the degradation of low density lipoprotein by cultured human skin fibroblasts. (1978) (96)
- Diet-Induced Increases in Adiposity, but Not Plasma Lipids, Promote Macrophage Infiltration Into White Adipose Tissue (2007) (95)
- Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters: ATP-Binding Cassette A-1, ATP-Binding Cassette G-1, and Scavenger Receptor B-1 (2013) (94)
- Interaction of native and modified low-density lipoproteins with extracellular matrix (2000) (93)
- Toll-Like Receptor 4 Deficiency Decreases Atherosclerosis But Does Not Protect Against Inflammation in Obese Low-Density Lipoprotein Receptor–Deficient Mice (2012) (93)
- Reduced Vascular Nitric Oxide–cGMP Signaling Contributes to Adipose Tissue Inflammation During High-Fat Feeding (2011) (92)
- Human arterial wall cells secrete factors that are chemotactic for monocytes. (1983) (90)
- ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan Published, JLR Papers in Press, September 1, 2002. DOI 10.1194/jlr.M200322-JLR200 (2002) (90)
- Leptin deficiency suppresses progression of atherosclerosis in apoE-deficient mice. (2008) (86)
- Serum amyloid A: The “other” inflammatory protein (2006) (86)
- Dietary compliance and cardiovascular risk reduction with a prepared meal plan compared with a self-selected diet. (1997) (85)
- Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH[S] (2017) (81)
- Cell‐Associated and Extracellular Phospholipid Transfer Protein in Human Coronary Atherosclerosis (2003) (80)
- Apolipoprotein E localization in human coronary atherosclerotic plaques by in situ hybridization and immunohistochemistry and comparison with lipoprotein lipase. (1994) (80)
- CREB Downregulation in Vascular Disease: A Common Response to Cardiovascular Risk (2010) (78)
- Evidence for kinetic heterogeneity among human low density lipoproteins. (1986) (78)
- Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease (2020) (78)
- Chylomicronemia Syndrome in Diabetes Mellitus (1981) (77)
- Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice (2008) (76)
- Myeloperoxidase Generates 5-Chlorouracil in Human Atherosclerotic Tissue (2006) (75)
- Oxidation-specific epitopes in human coronary atherosclerosis are not limited to oxidized low-density lipoprotein. (1996) (75)
- Lipoprotein modification: cellular mechanisms (1994) (74)
- TYPE-III HYPERLIPOPROTEINÆMIA ("REMNANT REMOVAL DISEASE") Insight into the Pathogenetic Mechanism (1977) (74)
- Serum amyloid A impairs the antiinflammatory properties of HDL. (2016) (74)
- Probucol treatment affects the cellular composition but not anti-oxidized low density lipoprotein immunoreactivity of plaques from Watanabe heritable hyperlipidemic rabbits. (1991) (74)
- Apolipoprotein A-I Attenuates Palmitate-Mediated NF-κB Activation by Reducing Toll-Like Receptor-4 Recruitment into Lipid Rafts (2012) (73)
- Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. II. Cellular composition and proliferation. (1995) (72)
- Antioxidant vitamins and lipid therapy: end of a long romance? (2002) (72)
- Severe hypertriglyceridemia: role of familial and acquired disorders. (1983) (72)
- Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis. (2011) (71)
- Serum lipoprotiens in four European communities: a quantitative comparison (1978) (67)
- Multicenter randomized trial of a comprehensive prepared meal program in type 2 diabetes. (1999) (67)
- Factors affecting blood pressure responses to diet: the Vanguard study. (2000) (65)
- Impaired very low density lipoprotein and triglyceride removal in broad beta disease: comparison with endogenous hypertriglyceridemia. (1978) (63)
- Phagocytosis of lipase-aggregated low density lipoprotein promotes macrophage foam cell formation. Sequential morphological and biochemical events. (1991) (63)
- Serum Amyloid A Facilitates the Binding of High-Density Lipoprotein From Mice Injected With Lipopolysaccharide to Vascular Proteoglycans (2011) (63)
- Diabetes and Arterial Extracellular Matrix Changes in a Porcine Model of Atherosclerosis (2007) (62)
- Effect of dietary fructose on triglyceride transport and glucoregulatory hormones in hypertriglyceridemic men. (1979) (62)
- Elevated plasma low-density lipoprotein and high-density lipoprotein cholesterol levels in amenorrheic athletes: effects of endogenous hormone status and nutrient intake. (1993) (61)
- Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells: inhibition of cholesterol esterification by oxidatively modified low density lipoprotein. (1989) (61)
- Serum amyloid A impairs the antiinflammatory properties of HDL. (2016) (61)
- The Chylomicronemia Syndrome Is Most Often Multifactorial (2019) (60)
- Low density lipoprotein receptor activity in freshly isolated human blood monocytes and lymphocytes. (1982) (60)
- MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. (2001) (59)
- Heterogeneity of primary lipoprotein lipase deficiency. (1980) (58)
- Pathophysiology of lipoprotein transport. (1978) (57)
- Saturated fatty acids and inflammation: who pays the toll? (2010) (56)
- Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice (2014) (55)
- Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease. (1999) (54)
- The biology of the artery wall in atherogenesis. (1994) (53)
- Regulation of the low density lipoprotein receptor and hydroxymethylglutaryl coenzyme A reductase genes by protein kinase C and a putative negative regulatory protein. (1989) (52)
- Effects of combination lipid therapy on coronary stenosis progression and clinical cardiovascular events in coronary disease patients with metabolic syndrome: a combined analysis of the Familial Atherosclerosis Treatment Study (FATS), the HDL-Atherosclerosis Treatment Study (HATS), and the Armed For (2009) (51)
- Secretion of a lipid transfer protein by human monocyte-derived macrophages. (1985) (51)
- The effect of dietary cholesterol on macrophage accumulation in adipose tissue: implications for systemic inflammation and atherosclerosis (2009) (51)
- Involvement of second messengers in regulation of the low-density lipoprotein receptor gene (1989) (50)
- Human Monocyte-derived Macrophages Secrete Two Forms of Proteoglycan-Macrophage Colony-stimulating Factor That Differ in Their Ability to Bind Low Density Lipoproteins* (1998) (50)
- Defective thyroid hormone action in fibroblasts cultured from subjects with the syndrome of resistance to thyroid hormones. (1982) (49)
- Obese Mice Losing Weight Due to trans-10,cis-12 Conjugated Linoleic Acid Supplementation or Food Restriction Harbor Distinct Gut Microbiota. (2018) (49)
- Biglycan, a Vascular Proteoglycan, Binds Differently to HDL2 and HDL3: Role of ApoE (2001) (49)
- Monocyte-to-Macrophage Differentiation (2012) (49)
- Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association. (2022) (47)
- Low-density lipoproteins modified by lipid transfer protein have altered biological activity. (1984) (46)
- Smooth muscle cell biglycan overexpression results in increased lipoprotein retention on extracellular matrix: implications for the retention of lipoproteins in atherosclerosis. (2004) (45)
- Lipoprotein lipase gene expression in THP-1 cells. (1989) (45)
- Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline. (2020) (44)
- Ascorbic acid clearance in diabetic nephropathy. (1998) (44)
- Nutritionally complete prepared meal plan to reduce cardiovascular risk factors: a randomized clinical trial. (1999) (44)
- The acute phase reactant response to respiratory infection with Chlamydia pneumoniae: implications for the pathogenesis of atherosclerosis. (2010) (43)
- Arterial smooth muscle cell proteoglycans synthesized in the presence of glucosamine demonstrate reduced binding to LDL. (2002) (43)
- Mineral loss in the parenteral nutrition patient. (1988) (42)
- Low Density Lipoprotein Receptor Activity in Fibroblasts Cultured from Diabetic Donors (1979) (42)
- A Comprehensive Update on the Chylomicronemia Syndrome (2020) (42)
- 10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species (2013) (41)
- Niacin plus Simvastatin Reduces Coronary Stenosis Progression Among Patients with Metabolic Syndrome Despite a Modest Increase in Insulin Resistance: A Subgroup Analysis of the HDL-Atherosclerosis Treatment Study (HATS). (2007) (38)
- Lysophosphatidylcholine Regulates Synthesis of Biglycan and the Proteoglycan Form of Macrophage Colony Stimulating Factor (2003) (38)
- Metabolism of modified LDL by cultured human placental cells. (1995) (37)
- Lipids, Lipoproteins, and Cardiovascular Disease: Clinical Pharmacology Now and in the Future. (2016) (37)
- Lipoprotein lipase is produced by cardiac myocytes rather than interstitial cells in human myocardium. (1994) (36)
- Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation (2016) (36)
- TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease Published, JLR Papers in Press, February 11, 2006. (2006) (36)
- Methods for assessing lipid and lipoprotein oxidation (1992) (35)
- Postprandial adipose tissue lipoprotein lipase activity in primary hypertriglyceridemia. (1980) (35)
- Mechanisms of enhanced macrophage apoE secretion by oxidized LDL. (1997) (34)
- Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice. (2007) (34)
- Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice (2013) (34)
- Autoregulation of the Modified Low Density Lipoprotein Receptor in Human Monocyte‐Derived Macrophages (1982) (34)
- The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice (2003) (33)
- Annular protrusion: pathophysiology and roentgenographic appearance. (1988) (33)
- Lipid Composition of Aorta of Watanabe Heritable Hyperlipemic and Comparably Hypercholesterolemic Fat‐fed Rabbits: Plasma Lipid Composition Determines Aortic Lipid Composition of Hypercholesterolemic Rabbits (1988) (33)
- T Cell Activation Inhibitors Reduce CD8+ T Cell and Pro-Inflammatory Macrophage Accumulation in Adipose Tissue of Obese Mice (2013) (32)
- Regulation of LTP-I secretion from human monocyte-derived macrophages by differentiation and cholesterol accumulation in vitro. (1990) (32)
- Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein (2017) (31)
- Bacterial lipopolysaccharide reduces macrophage lipoprotein lipase levels: an effect that is independent of tumor necrosis factor. (1988) (31)
- A Secretory Product of Human Monocyte‐Derived Macrophages Stimulates Low Density Lipoprotein Receptor Activity in Arterial Smooth Muscle Cells and Skin Fibroblasts (1982) (31)
- Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet (2015) (31)
- Modulation of adipose tissue lipolysis and body weight by high-density lipoproteins in mice (2014) (31)
- Transcriptional activation of the lipoprotein lipase gene in macrophages by dexamethasone. (1991) (31)
- Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans (2004) (30)
- HDL Lipids and Insulin Resistance (2010) (30)
- Uptake of chylomicron remnants by the native LDL receptor in human monocyte-derived macrophages. (1981) (30)
- Gain and Loss of Function for Glutathione Synthesis: Impact on Advanced Atherosclerosis in Apolipoprotein E–Deficient Mice (2011) (30)
- Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice (2017) (29)
- VASP Increases Hepatic Fatty Acid Oxidation by Activating AMPK in Mice (2013) (29)
- Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300252-JLR200 (2003) (29)
- Hydrocortisone decreases the internalization of low density lipoprotein in cultured human fibroblasts and arterial smooth muscle cells (1983) (29)
- Cholesterol accumulation in aortic smooth muscle cells exposed to low density lipoproteins. Contribution of free cholesterol transfer. (1988) (28)
- The p17 Cleaved Form of Caspase-3 Is Present Within Viable Macrophages In Vitro and in Atherosclerotic Plaque (2003) (28)
- Lipoprotein-matrix interactions in macrovascular disease in diabetes. (2004) (27)
- Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: kinetic analysis using an integrated model. (1986) (26)
- Inhibition of LDL oxidation in vitro but not ex vivo by troglitazone. (1999) (26)
- Increased uptake of alpha-hydroxy aldehyde-modified low density lipoprotein by macrophage scavenger receptors. (2000) (26)
- Oxidized LDL bind to nonproteoglycan components of smooth muscle extracellular matrices. (2001) (26)
- Treatment of Dyslipidemia in Diabetes: Recent Advances and Remaining Questions (2017) (26)
- Reduction of plasma triglyceride concentration by acute stress in man. (1979) (25)
- Effect of donor age on the binding and degradation of low density lipoproteins by cultured human arterial smooth muscle cells. (1979) (25)
- Chylomicronemia syndrome. (1992) (24)
- Adipocytokines as features of the metabolic syndrome determined using confirmatory factor analysis. (2013) (24)
- Inhibition of low density lipoprotein oxidation in vitro by the 6- and 7-hydroxy-metabolites of doxazosin, an alpha 1-adrenergic antihypertensive agent. (1994) (24)
- Loss of copper-zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin. (1989) (24)
- Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation (2012) (24)
- Immunohistochemical distribution of lipoprotein epitopes in xanthomata from patients with familial hypercholesterolemia. (1992) (24)
- Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice. (2006) (24)
- D-lactate and metabolic bone disease in patients receiving long-term parenteral nutrition. (1989) (23)
- Apolipoprotein E Mediates the Retention of High-Density Lipoproteins by Mouse Carotid Arteries and Cultured Arterial Smooth Muscle Cell Extracellular Matrices (2002) (22)
- An Alternative Approach: Antegrade Catheter-directed Thrombolysis in a Case of Phlegmasia Cerulea Dolens (1999) (22)
- AUDIT study. Evidence of global undertreatment of dyslipidaemia in patients with type 2 diabetes mellitus (2006) (22)
- FREQUENCY OF RISK FACTORS FOR ISCHÆMIC HEART-DISEASE IN A HEALTHY BRITISH POPULATION (1974) (22)
- Functional overlap between "chylomicra" and "very low density lipoproteins" of human plasma during alimentary lipaemia. (1973) (22)
- Acceleration of Low-Density Lipoprotein Catabolism in Man by Total Parenteral Nutrition (1981) (21)
- Lipid altering or antioxidant vitamins for patients with coronary disease and very low HDL cholesterol? The HDL-Atherosclerosis Treatment Study Design. (1998) (21)
- A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome (2018) (20)
- Progression of atherosclerosis: the cell biology. (1987) (20)
- IGF-1 induces rat glomerular mesangial cells to accumulate triglyceride. (2006) (19)
- LIPODYSTROPHY WITH HYPERLIPIDAEMIA: THE ROLE OF INSULIN IN VERY LOW DENSITY LIPOPROTEIN OVER‐SYNTHESIS (1979) (19)
- Potential of essential fatty acid deficiency with extremely low fat diet in lipoprotein lipase deficiency during pregnancy: A case report (2004) (18)
- Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity. (2020) (18)
- Simvastatin plus niacin protect against atherosclerosis progression and clinical events in coronary artery disease patients with metabolic syndrome (2002) (18)
- Ex vivo measures of LDL oxidative susceptibility predict carotid artery disease. (2005) (18)
- The relationship between dietary fat composition and plasma cholesterol esterification in man. (1975) (17)
- Hypertriglyceridemia: Pathophysiology, Role of Genetics, Consequences, and Treatment (2000) (16)
- Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. (2022) (16)
- Role of ApoE (2000) (16)
- Comprehensive nutrition plan improves cardiovascular risk factors in essential hypertension. (1998) (14)
- Comparison of Methods of Plasma Triglyceride Turnover (1977) (14)
- The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. (1981) (14)
- 3.C.2 Interaction of oxidized LDL with arterial proteoglycans (1997) (14)
- From the American Heart Association Diabetes and Cardiovascular Disease : A Statement for Healthcare Professionals (2010) (13)
- Antioxidants Inhibit the Ability of Lysophosphatidylcholine to Regulate Proteoglycan Synthesis (2005) (13)
- Apolipoproteins and Diabetic Retinopathy (2011) (13)
- The effect of dietary fat on platelet function. (1973) (12)
- Effects of antihypertensive agents on serum lipids and lipoproteins. (1989) (12)
- Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial (2021) (11)
- Experience with Simplified Scheme of Treatment of Hyperlipidaemia (1974) (11)
- Biochemical and Molecular Roles of Nutrients Dietary Isoflavones Reduce Plasma Cholesterol and Atherosclerosis in C 57 BL / 6 Mice but not LDL Receptor – Deficient Mice 1 , 2 (1998) (11)
- Intravenous fat-tolerance test in ischaemic heart disease and peripheral vascular disease. (1976) (10)
- Successful pregnancy outcome using total parenteral nutrition from the first trimester of pregnancy. (1986) (10)
- Catabolism of very-low-density lipoproteins in subjects with broad beta disease: comparison with endogenous hypertriglyceridemia. (1982) (10)
- Triglyceride-rich lipoproteins from subjects with type 2 diabetes do not demonstrate increased binding to biglycan, a vascular proteoglycan. (2002) (10)
- The Apolipoprotein-AI Mimetic Peptide L4F at a Modest Dose Does Not Attenuate Weight Gain, Inflammation, or Atherosclerosis in LDLR-Null Mice (2014) (9)
- Presence of serum amyloid A3 in mouse plasma is dependent on the nature and extent of the inflammatory stimulus (2020) (9)
- Stimulation of receptor-dependent and receptor-independent pathways of low-density lipoprotein degradation in arterial smooth muscle cells by platelet-derived growth factor. (1988) (9)
- Genetic Disorders of Triglyceride Metabolism (2015) (9)
- Adipose Tissue Inflammation and Atherogenesis in the Metabolic Syndrome(Symposium 3 (SY-03) (IHD) Metabolic Syndrome and Atherosclerosis,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society) (2008) (9)
- Red Cell Oxygen Affinity in Severe Hypertriglyceridemia 1 (1978) (8)
- Familial hyperuricaemia and hypertriglyceridaemia. (1973) (8)
- Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr−/− Mice (2018) (8)
- Pulmonary embolism: influence of cardiac hemodynamics and natural history on selection of patients for embolectomy and inferior vena cava ligation. (1969) (8)
- Aortoiliac arteriovenous fistula simulating iliac vein thrombosis following intervertebral disc surgery. (1983) (8)
- Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro. (1998) (8)
- The wandering coronary stent. Case report. (1998) (8)
- Chronic insulin therapy reduces adipose tissue macrophage content in LDL-receptor-deficient mice (2011) (8)
- ApoE enhances lipid uptake by macrophages in lipoprotein lipase deficiency during pregnancy. (1996) (7)
- Lipid abnormalities in alcoholism and chronic renal failure. (1973) (7)
- Familial Combined Hyperlipidemia and Familial Hypertriglyceridemia (1987) (7)
- Apolipoprotein A-I and HDL Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters: ATP-Binding Cassette (ABC) A-1, ABCG-1 and Scavenger Receptor B-1(SRB-1) (2013) (6)
- The role of lipoprotein receptors in lipid transport and in the pathogenesis of the hyperlipoproteinemias. (1983) (6)
- Glycation of HDL blunts its anti-inflammatory and cholesterol efflux capacities in vitro, but has no effect in poorly controlled type 1 diabetes subjects. (2020) (6)
- Scavenger lipoprotein receptors are more effective in ligand internalization than low density lipoprotein receptors in human monocyte-macrophages. (1983) (6)
- Antioxidant Vitamins and Lipid Therapy (2002) (5)
- Metabolic consequences of genetic heterogeneity of lipoprotein composition (lipoprotein heterogeneity). (1987) (5)
- Low-density lipoprotein oxidation and the pathogenesis of atherosclerosis. (1994) (4)
- Lysosomal enzyme activities and low density lipoprotein receptors in circulating mononuclear cells (1981) (4)
- Removal of low density lipoproteins in sheep by extracorporeal affinity chromatography. (1981) (4)
- Healthier diets improve quality of life while reducing cardiovascular disease risk factors (1998) (4)
- Lipoprotein Metabolism: Structure and Function (2003) (4)
- P-Selectin Glycoprotein Ligand-1: A Cellular Link Between Perivascular Adipose Inflammation and Endothelial Dysfunction (2012) (4)
- Versican synthesized in the presence of troglitazone is smaller and has reduced LDL binding (2002) (3)
- The effect of human T and B lymphocytes on low-density lipoprotein catabolism by cultured fibroblasts. (1983) (3)
- 4 – Very Low Density Lipoprotein Kinetics in Familial Forms of Hypertriglyceridemia (1982) (3)
- Serum amyloid A–containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties (2020) (3)
- A Randomized Control Trial of the Effects of a Comprehensive Risk Reduction Nutrition Program on Plasma Homocysteine Levels in Hypertensives with Associated Cardiovascular Risk Factors. (1996) (3)
- HETEROGENEITY OF HUMAN GROWTH HORMONE IN PLASMA AND URINE: INFLUENCE OF GROWTH HORMONE RELEASE INHIBITING HORMONE (1975) (3)
- Hypertriglyceridemia. (2022) (2)
- Actions of transforming growth factor-β in a cultured vascular smooth muscle cell model for studying the “response-to-retention” hypothesis of atherosclerosis (2000) (2)
- Hematopoietic Cell–Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance (2020) (2)
- Regulation of low density lipoprotein degradation by triiodothyronine (1978) (2)
- Hyperlipidemia: forestalling complications in older diabetics. (1985) (2)
- The hyperlipidaemias--a rational approach to classification and management. (1972) (2)
- Sexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3), Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice (2021) (2)
- Chylomicra and very-low density lipoproteins--are they functionally distinct? (1972) (2)
- Lipoprotein Heterogeneity Workshop (2005) (2)
- Nutrition and inflammation: role of dietary cholesterol (2004) (2)
- Bromocriptine Treatment ofAcromegaly (1975) (2)
- Modification of the Rate of Secretion of Triglyceride into Plasma by Dietary Polyunsaturated Fat (1975) (2)
- Diabetes and cardiovascular disease. Introduction. (2006) (1)
- HDL-associated serum amyloid A (SAA) may be a predictor of cardiovascular risk independent of HDL- or LDL-cholesterol. (2017) (1)
- Abstract 414: Local Artery Wall Inflammation Overrides Systemic Inflammation in Diabetes-Accelerated Atherosclerosis (2018) (1)
- Secondary hyperlipidaemia. (1973) (1)
- A study of hyper-beta- and hyperpre-beta-lipoproteinaemia. (1972) (1)
- Studies on plasma lipid metabolism in diabetes. (1972) (1)
- Influence of saturated and unsaturated dietary fat on diurnal changes in plasma triglyceride and lipoprotein levels. (1973) (1)
- Associated With the ApolipoproteinC-III Content of ApoB Particles Among Those With Diabetes Mellitus (2004) (1)
- Approach to patients with hypertriglyceridemia. (2022) (1)
- Plasminogen activator inhibitor-1 (PAI-1) and c-reactive protein (CRP) comprise integral components of the metabolic syndrome (2012) (1)
- The pro-inflammatory nature of the vascular extracellular matrix (2004) (1)
- Summary of Discussion (1981) (1)
- 1103-167 Accelerated coronary stenosis progression is associated with the apolipoprotein C-III content of ApoB particles among those with diabetes mellitus (2004) (1)
- Strategies to Achieve Target LDL Levels (2010) (0)
- 177-OR: Genome-Wide Association Study of Lipid Traits in Youth with Type 2 Diabetes: The ProDiGY (Progress in Diabetes Genetics in Youth) Consortium (2019) (0)
- Table 2, Selected genes with roles in FCHL (2015) (0)
- 116 PYRIDOXAMINE DID NOT HAVE A MARKED HYPOLIPIDEMIC EFFECT IN LOW DENSITY LIPOPROTEIN DEFICIENT MICE: A MODEL FOR STUDYING THE EFFECT OF CARBONYL SCAVENGERS ON ATHEROSCLEROSIS (2005) (0)
- Abstract 390: A New Humanized Mouse Model to Study Lipid Abnormalities and HDL Function in Poorly Controlled Type 1 Diabetes Mellitus (2018) (0)
- TGF-beta 1 increases LDL retention by vascular proteoglycans (2001) (0)
- Erratum to: Chronic insulin therapy reduces adipose tissue macrophage content in LDL-receptor-deficient mice (2011) (0)
- Preventing cardiovascular disease in type 2 diabetes: Where do things stand with glycemic control? Part one (2009) (0)
- Mo-W2:1 Diabetes and the vascular wall: Role of inflammatory molecules (2006) (0)
- Update on Lipids and Lipoproteins. (2022) (0)
- Lipids: Update on Diagnosis and Management of Dyslipidemia (2022) (0)
- Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis (2022) (0)
- Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia (1980) (0)
- Serum Lipoprotein Abnormalities in Ischaemic Heart Disease and Peripheral Vascular Disease (1974) (0)
- Symposium - Is medical treatment of coronary artery disease superior to revasculation procedures?, Vancouver, BC, Canada, 31 May 1997 (1998) (0)
- Multicenter Randomized Trial of a C o m p rehensive Pre p a red Meal Pro g r a m in Type 2 Diabetes (1999) (0)
- Abstract 118: Cholesteryl Ester Transfer Protein Overrides The Protective Effect Of APOA1 On Arterial APOB Lipoprotein Trapping And Atherosclerosis Progression In A Mouse Model Of Type 1 Diabetes (2022) (0)
- Abstract 17092: Apolipoprotein-A1 (ApoA-1) Diminishes Lipid Raft Content and Reduces Vascular Inflammation (2010) (0)
- 901-122 Oxidized LDL Stimulates Mitogen-activated Protein Kinases in Smooth Muscle Cells and Macrophages (1995) (0)
- Letters to the EditorALCOHOLIC HYPERLIPIDÆMIA (1972) (0)
- STUDIES ON THE MODE OF ACTION AND ON VERY LOW DENSlTY LIPOPROTEIN COMPOSITION (1974) (0)
- Oxidized low density lipoprotein and cardiovascular risk. (1996) (0)
- Rapid Publication (2003) (0)
- Approach to patients with elevated low-density lipoprotein cholesterol levels. (2022) (0)
- LDL binding to its cellular receptor (1978) (0)
- The Effect of Concanavalin A-Stimulated Mononuclear Cells on Low Density Lipoprotein Receptor Activity of Cultured Fibroblasts (1985) (0)
- HDLC as a therapeutic target in coronary disease: current concepts and future directions (1995) (0)
- Table 4, Secondary causes that can contribute to severe HTG (2015) (0)
- Oxidative modification of lipoproteins and their treatment in primates (1994) (0)
- Table 1, Definition of hypertriglyceridemia according to various clinical guidelines (2015) (0)
- Abstract 59: Altering Levels of Invariant Natural Killer T Cells Does Not Improve Adipose Tissue Inflammation or Insulin Sensitivity in Diet-Induced Obesity (2012) (0)
- Figure 1, Palmar Xanthomas: Note the orange-yellow discoloration confined to the palmar creases. (2015) (0)
- Abstract 688: Trans-10, Cis-12 Conjugated Linoleic Acid Induces a Lipodystrophic Phenotype and Browning of White Adipose Tissue in a Mouse Model of the Metabolic Syndrome (2015) (0)
- Proceedings: Serum lipoprotein abnormalities in ischaemic heart disease and peripheral vascular disease. (1974) (0)
- Abstract 242: Sexual Dimorphic Effects of Serum Amyloid A3 in Atherosclerosis in Mice (2018) (0)
- Proceedings: Unsaturated fat and plasma triglyceride metabolism in man. (1974) (0)
- Abstract 315: Inflamed HDL Loses Its Anti-inflammatory Properties on Adipocytes: Role of Interaction of Serum Amyloid A with the Extracellular Matrix (2015) (0)
- Atherosclerosis: cell biology and lipoproteins Editorial overview (1991) (0)
- Figure 2, [Eruptive xanthomas. The commonest site...]. (2015) (0)
- Reply to ST Mayne and B Cartmel (1999) (0)
- Preventing cardiovascular disease in type 2 diabetes: Where do things stand with glycemic control? Part two (2009) (0)
- Dyslipidemia in Diabetes (2019) (0)
- Rapid Publication Iron and Copper Promote Modification of Low Density Lipoprotein by Human Arterial Smooth Muscle Cells in Culture (2013) (0)
- Figure 3, [Lipemia retinalis. Note the pale color of the retinal vessels.]. (2015) (0)
- A CASE OF STRUMA CARCINOID AND GRAVES DISEASE (2017) (0)
- Atherosclerotic Plaques : Colocalization of Biglycan With Apolipoproteins Comparison of Apolipoprotein and Proteoglycan Deposits in Human Coronary (1998) (0)
- Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes (2014) (0)
- In Memoriam: Dr German A. Camejo (1936-2021). (2022) (0)
- 422 GLUCOSAMINE EXACERBATES DYSLIPIDEMIA IN LOW-DENSITY LIPOPROTEIN RECEPTOR DEFICIENT MICE. (2004) (0)
- The effect of insulin on the interaction of lipoproteins with cultured cells (1977) (0)
- Abstract 114: Serum Amyloid A Plays an Important Role in Making HDL Lose Its Anti-inflammatory Effect on Adipocytes (2015) (0)
- Presence of serum amyloid A3 in mouse plasma is dependent on the nature and extent of the inflammatory stimulus (2020) (0)
- Chylomicronemia Syndrome: Very Severe Hypertriglyceridemia and Acute Pancreatitis (2014) (0)
- Recent advances in lipidology. (2023) (0)
- Tu-P7:191 Inflammation impairs the ability of mouse serum to remove cellular lipids by the ABCA1 pathway (2006) (0)
- The Chylomicronemia Syndrome IsMost OftenMultifactorial ANarrative Review of Causes and Treatment (2019) (0)
- Ethanol impairs low density lipoprotein metabolism by cultured human cells (1978) (0)
- Short title: A Role of VASP on hepatic fatty acid oxidation (2013) (0)
- Abstract 365: Inhibiting Hmg Coa Reductase Reduces Palmitate-Induced Inflammation in Adipocytes (2017) (0)
- Paraoxonase protects low density lipoprotein (LDL) against copper mediated oxidation (1996) (0)
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What Schools Are Affiliated With Alan Chait?
Alan Chait is affiliated with the following schools:
