Alan Cowan
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Medical Philosophy
Alan Cowan's Degrees
- PhD Pharmacology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Alan Cowan Influential?
(Suggest an Edit or Addition)Alan Cowan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- AGONIST AND ANTAGONIST PROPERTIES OF BUPRENORPHINE, A NEW ANTINOCICEPTIVE AGENT (1977) (517)
- pA2 and receptor differentiation: a statistical analysis of competitive antagonism. (1979) (398)
- Statistical analysis of drug-drug and site-site interactions with isobolograms. (1989) (385)
- The rat paw formalin test: comparison of noxious agents (1990) (357)
- Narcotic analgesics and antagonists. (1971) (341)
- Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist. (2001) (321)
- THE ANIMAL PHARMACOLOGY OF BUPRENORPHINE, AN ORIPAVINE ANALGESIC AGENT (1977) (310)
- Buprenorphine: a unique drug with complex pharmacology. (2004) (266)
- A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. (2005) (236)
- Standardization of the rat paw formalin test for the evaluation of analgesics (2005) (230)
- Methodological refinements to the mouse paw formalin test. An animal model of tonic pain. (1988) (221)
- Direct dependence studies in rats with agents selective for different types of opioid receptor. (1988) (174)
- Comparison of Pharmacological Activities of Three Distinct κ Ligands (Salvinorin A, TRK-820 and 3FLB) on κ Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo (2005) (172)
- Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model (1991) (153)
- Classification of opioids on the basis of change in seizure threshold in rats. (1979) (152)
- Neurogenic and tissue-mediated components of formalin-induced edema: Evidence for supraspinal regulation (1991) (123)
- Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive Activity (2010) (119)
- Rat cold water tail-flick: a novel analgesic test that distinguishes opioid agonists from mixed agonist-antagonists. (1985) (107)
- Buprenorphine: combatting drug abuse with a unique opioid (1995) (102)
- Buprenorphine: new pharmacological aspects. (2003) (93)
- Kappa opioid agonists suppress chloroquine-induced scratching in mice. (2004) (88)
- Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: demonstration of an opioid kappa and delta inhibitory tone. (1996) (88)
- Targeting Itch with Ligands Selective for κ Opioid Receptors. (2015) (83)
- Supraspinal and spinal potency of selective opioid agonists in the mouse writhing test. (1987) (77)
- Testing and evaluation of drugs of abuse (1990) (77)
- Studies on bombesin-induced grooming in rats (1983) (68)
- Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration. (1981) (68)
- Analgesic and toxic effects of neonicotinoid insecticides in mice. (2001) (67)
- Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion (2018) (65)
- Naloxone antagonizes behavioural effects of d-amphetamine in mice and rats (1978) (65)
- Buprenorphine: The Basic Pharmacology Revisited (2007) (60)
- Nalfurafine, a kappa opioid receptor agonist, inhibits scratching behavior secondary to cholestasis induced by chronic ethynylestradiol injections in rats (2006) (59)
- Electromagnetic millimeter wave induced hypoalgesia: Frequency dependence and involvement of endogenous opioids (2008) (59)
- Expression of TCTP antisense in CD25(high) regulatory T cells aggravates cuff-injured vascular inflammation. (2009) (58)
- 2-Methoxymethyl-Salvinorin B Is a Potent κ Opioid Receptor Agonist with Longer Lasting Action in Vivo Than Salvinorin A (2008) (55)
- Buprenorphine and morphine cause antinociception by different transduction mechanisms. (1991) (54)
- Independent central and peripheral mediation of morphine-induced inhibition of gastrointestinal transit in rats. (1986) (53)
- IV. Effects of bombesin on behavior (1985) (52)
- Antinociceptive Synergy, Additivity, and Subadditivity with Combinations of Oral Glucosamine Plus Nonopioid Analgesics in Mice (2003) (52)
- Abrupt or precipitated withdrawal from morphine induces immunosuppression (2002) (52)
- Studies in vivo with ICI 174864 and [ D-Pen2, D-Pen5 ]enkephalin (1985) (50)
- Characterization of the pharmacokinetics of buprenorphine and norbuprenorphine in rats after intravenous bolus administration of buprenorphine. (2002) (50)
- Ketazocines and morphine: effects on gastrointestinal transit after central and peripheral administration. (1983) (49)
- Opiate-like electroencephalographic and behavioral effects of electroconvulsive shock in rats. (1981) (49)
- Higher expression of Bax in regulatory T cells increases vascular inflammation. (2008) (46)
- Nalfurafine prevents 5′-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5′-guanidinonaltrindole-elicited scratching behavior in mice (2009) (46)
- Administration of mu-, kappa- or delta2-receptor agonists via osmotic minipumps suppresses murine splenic antibody responses. (2001) (45)
- Naloxone causes apparent antinociception and pronociception simultaneously in the rat paw formalin test. (1993) (44)
- Hypoalgesic effect of millimeter waves in mice: dependence on the site of exposure. (2000) (43)
- N-Methyl-d-aspartate Antagonists and WIN 55212-2 [4,5-Dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i,j]quinolin-6-one], a Cannabinoid Agonist, Interact to Produce Synergistic Hypothermia (2002) (42)
- Peripheral neural system involvement in hypoalgesic effect of electromagnetic millimeter waves. (2001) (42)
- Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation. (2008) (41)
- Suppression of pain sensation caused by millimeter waves: a double-blinded, cross-over, prospective human volunteer study. (1999) (41)
- Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig (2011) (40)
- Studies on opioid peptides as endogenous anticonvulsants. (1982) (40)
- Antipruritic effect of millimeter waves in mice: evidence for opioid involvement. (1998) (37)
- In-vivo studies on kappa opioid receptors (1986) (36)
- Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit. (2006) (35)
- Studies on the excitatory and inhibitory influence of intracerebroventricularly injected opioids on seizure thresholds in rats (1984) (33)
- Pain relief caused by millimeter waves in mice: results of cold water tail flick tests. (2000) (33)
- Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys. (1973) (33)
- Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats (2006) (32)
- Nalbuphine, a kappa opioid receptor agonist and mu opioid receptor antagonist attenuates pruritus, decreases IL-31, and increases IL-10 in mice with contact dermatitis. (2019) (29)
- Phoenixin: A candidate pruritogen in the mouse (2015) (29)
- Simple in vivo tests that differentiate prototype agonists at opiate receptors. (1981) (29)
- Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. (2009) (28)
- Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists. (1991) (28)
- EEG, EMG and behavioral evidence for the involvement of endorphin systems in postictal events after electroconvulsive shock in rats. (1982) (28)
- Tolerance and cross‐tolerance studies with morphine and ethylketocyclazocine (1982) (28)
- Scratching activates microglia in the mouse spinal cord (2015) (27)
- Investigation of gastrin-releasing peptide as a mediator for 5′-guanidinonaltrindole-induced compulsive scratching in mice (2011) (27)
- A comparison of the anticonvulsant effects of two systemically active enkephalin analogues in rats. (1981) (27)
- Development and validation of a sensitive analytical method for the simultaneous determination of buprenorphine and norbuprenorphine in human plasma. (2001) (27)
- Opioids: past, present and future (1984) (25)
- Antipruritic and antihyperalgesic actions of loperamide and analogs. (2002) (25)
- Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice (2009) (25)
- In vivo evidence for benzomorphan-selective receptors in rats. (1984) (24)
- An antisense oligodeoxynucleotide to the mu opioid receptor attenuates cocaine-induced behavioral sensitization and reward in mice (2006) (23)
- Morphine Inhibits Mucosal Antibody Responses and TGF-β mRNA in Gut-Associated Lymphoid Tissue Following Oral Cholera Toxin in Mice1 (2001) (23)
- Intrathecal bombesin in rats: effects on behaviour and gastrointestinal transit. (1983) (23)
- Classification of opioids on the basis of their ability to antagonize bombesin-induced grooming in rats. (1982) (22)
- A species difference in the slowing effect of intrathecal morphine on gastrointestinal transit. (1983) (22)
- Role of Opioid Receptors in Bombesin‐induced Grooming a (1988) (21)
- A quantitative analysis of the shaking behavior induced in rats by beta-endorphin and [D-Ala2, Met5]enkephalinamide. (1982) (21)
- Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats (2005) (21)
- Use of a programmable protocol timer and data logger in the monitoring of animal behavior (1981) (21)
- The affinity of morphine for its pharmacologic receptor in vivo. (1982) (20)
- Effects of bombesin on behavior. (1985) (20)
- Proceedings: The effects of buprenorphine, morphine and pentazocine on turning behaviour and stereotypy induced by apomorphine in the rat. (1975) (20)
- The effect of pentobarbital on the antinociceptive action of morphine in morphine-tolerant and non-tolerant rats. (1979) (19)
- A selective role for delta-receptors in the regulation of opioid-induced changes in seizure threshold. (1983) (19)
- Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats. (2006) (19)
- Eeg and behavioral effects of ethylketocyclazocine, morphine and cyclazocine in rats: Differential sensitivities towards naloxone (1980) (18)
- Reduced kappa-opioid activity in a rat model of cholestasis. (2005) (18)
- Neurokinin-induced salivation in the anesthetized rat: a three receptor hypothesis. (1987) (18)
- NMDA receptors modulate morphine-induced hyperthermia (2003) (18)
- Comparison of the diuretic effects of chemically diverse kappa opioid agonists in rats: nalfurafine, U50,488H, and salvinorin A (2009) (18)
- An animal model for preclinical screening of systemic antipruritic agents. (1983) (18)
- Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats. (1979) (17)
- ACTH-(1-24) and RX 336-M induce excessive grooming in rats through different mechanisms. (1983) (17)
- Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit (2014) (17)
- A proinflammatory chemokine , CCL 3 , sensitizes the heat-and capsaicin-gated ion channel TRPV 1 (2005) (17)
- Pharmacological analysis of receptors for bombesin-related peptides on guinea pig gallbladder smooth muscle (1994) (16)
- In vivo studies with ICI 154,129, a putative delta receptor antagonist. (1982) (16)
- Millimeter-wave-induced hypoalgesia in mice: dependence on type of experimental pain (2004) (16)
- Behavioral Effects of Bombesin a (1988) (16)
- BUPRENORPHINE AND GASTROINTESTINAL TRANSIT IN RATS: EFFECT OF NALOXONE ON THE BIPHASIC DOSE‐RESPONSE CURVE (1992) (15)
- μ and δ, but not κ, opioid agonists induce contractions of the canine small intestine in vivo (1985) (15)
- A comparison of the neurochemical effects of buprenorphine with those of morphine and haloperidol in rats. (1981) (15)
- Omeprazole-induced slowing of gastrointestinal transit in mice can be countered with tegaserod. (2005) (15)
- Analgesic and dependence studies with oripavine partial agonists. (1971) (14)
- Intrathecal morphine slows gastrointestinal transit in rats. (1985) (14)
- Icilin evokes a dose- and time-dependent increase in glutamate within the dorsal striatum of rats (2006) (14)
- ICI 154,129, a δ-opioid receptor antagonist raises seizure threshold in rats (1984) (14)
- Bombesin—a central mediator of pruritus? (1983) (14)
- Intrathecal bombesin-induced inhibition of gastrointestinal transit: requirement for an intact pituitary-adrenal axis (1986) (14)
- Phoenixin: a novel brain-gut-skin peptide with multiple bioactivity (2018) (14)
- RX 336-M, a new chemical tool in the analysis of the quasi-morphine withdrawal syndrome. (1981) (13)
- Effect of propranolol on antinociceptive, tolerance- and dependence-producing properties of morphine in rodents and monkeys. (1975) (13)
- Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production (2009) (13)
- Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats (1984) (13)
- Comparison of Pharmacological Activities of Three Distinct (cid:1) Ligands (Salvinorin A, TRK-820 and 3FLB) on (cid:1) Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo (2004) (13)
- Effects of intracerebroventricular β-funaltrexamine on μ and δ opioid receptors in the rat: dichotomy between binding and antinociception (1991) (13)
- Effect of nor-binaltorphimine on the behavior of mice and rats receiving multiple injections of U-50,488. (1990) (13)
- Lysergic acid diethylamide antagonizes shaking induced in rats by five chemically different compounds (1978) (13)
- Estimation in vivo of the receptor constants of morphine in naive and morphine-tolerant rats. (1982) (13)
- On the criteria for classifying opiate agonists in rats (1982) (12)
- New bombesin antagonist shown to have 'encouraging profile'. (1988) (12)
- Morphine-receptor dissociation constant and the stimulus-effect relation for inhibition of gastrointestinal transit in the rat. (1982) (12)
- Potentiation of non-N-methyl-d-aspartate receptor-induced changes in blood pressure by substance P in rats (2000) (12)
- A comparison of the receptor constants of morphine and ethylketocyclazocine for analgesia and inhibition of gastrointestinal transit in the rat. (1982) (12)
- Coadministration of Chemokine Receptor Antagonists with Morphine Potentiates Morphine’s Analgesic Effect on Incisional Pain in Rats (2018) (12)
- Kappa-Opioid Antagonists as Pruritogenic Agents (2009) (12)
- Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1α/CXCL12 in the brain. (2010) (11)
- Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors (2005) (11)
- Effects of Opioids on the Spontaneous Behavior of Animals (1993) (11)
- Modulation of delta opioid-evoked hypothermia in rats by WAY 100635 and fluoxetine (2006) (11)
- On deriving the dose-effect relation of an unknown second component: an example using buprenorphine preclinical data. (2010) (11)
- Zyklophin, a short-acting kappa opioid antagonist, induces scratching in mice (2014) (11)
- Pituitary opioid involvement in ECS-postictal electrogenesis and behavioral depression in rats (1984) (11)
- Opioid‐sparing effects of cannabinoids on morphine analgesia: participation of CB1 and CB2 receptors (2019) (11)
- A study of the shaking and grooming induced by RX 336-M in rats (1982) (10)
- Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum (2007) (10)
- Mu and delta, but not kappa, opioid agonists induce contractions of the canine small intestine in vivo. (1985) (10)
- The effect of acute doses of buprenorphine on concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) in the rat forebrain [proceedings]. (1976) (10)
- In vivo studies on delta opioid receptors. (1986) (10)
- Effects of selective opioid agonists on feline colonic transit. (1991) (10)
- Differential antinociceptive effects of buprenorphine and methadone in the presence of HIV-gp120. (2011) (9)
- Estimation of the dissociation constant of naloxone in the naive and morphine-tolerant guinea-pig isolated ileum: analysis by the constrained Schild plot. (1982) (9)
- The behavioural effects of levallorphan, cyprenorphine (M 285) and amphetamine on repeated Y-maze performance in rats (2004) (9)
- Lack of interaction between metoclopramide and morphine in vitro and in mice (2008) (9)
- Reversal of yeast‐induced motor impairment in rats as a test for narcotic and non‐narcotic analgesics (1974) (9)
- Reserpinization severs the cooperative but not the oppositional interaction between D1 and D2 receptors (1993) (9)
- Correlation between animal and clinical findings with a psychotomimetic anticholinesterase. (1973) (9)
- Antipruritic Effects of Kappa Opioid Receptor Agonists: Evidence from Rodents to Humans. (2020) (8)
- Chemokine Receptor Antagonists in Combination with Morphine as a Novel Strategy for Opioid Dose Reduction in Pain Management. (2020) (8)
- The effects of naloxone, chlorpromazine, and haloperidol pretreatment on levallorphan-induced disruption of rats' operant behaviour (2004) (8)
- Use of the formalin test in evaluating analgesics. (1989) (7)
- Pharmacology of Itch (2015) (7)
- Neuroadaptation of rats to kappa agonists U-50,488 and tifluadom. (1988) (7)
- Lack of adverse effects during a target animal safety trial of extended-release buprenorphine in Fischer 344 rats (2015) (7)
- The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs. (1996) (7)
- Time course of antagonism of morphine antinociception by intracerebroventricularly administered naloxone in the rat. (1981) (7)
- Association of nausea with buprenorphine analgesia for rats (2017) (7)
- Nitric oxide synthase mediates delta opioid receptor-induced hypothermia in rats. (2006) (7)
- Pupillary effects of leucine and methionine enkephalin in rats after intraperitoneal administration (1980) (7)
- Routine measurement of homovanillic acid in rat brain by gas‐liquid chromatography (1978) (7)
- Erratum: A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1 (Proceedings of the National Academy of Sciences of the United States of America (March 22, 2005) 102, 12 (4536-4541)) (2005) (7)
- Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic (2021) (7)
- Formalin nociception in the mouse does not lead to increased spinal serotonin turnover (1990) (7)
- Single millimeter wave treatment does not impair gastrointestinal transit in mice. (2002) (6)
- DEFINING THE ANTINOCISPONSIVE ACTIONS OF NEUROTENSIN (1982) (6)
- Cross-tolerance between morphine- and bombesin-induced inhibition of intestinal transit in rats. (1985) (6)
- Quasi-morphine withdrawal syndrome: recent developments. Introduction. (1981) (6)
- 428 – ISTUDIES ON THE QUANTITATIVE ANTAGONISM OF μ AND K RECEPTOR AGONISTS BY NALOXONE USING THE RAT TAIL COMPRESSION TEST (1978) (6)
- Increased Urine Output by Rats after Intracerebroventricular Administration of Kappa Agonists (1986) (6)
- Peripheral κ-Opioid Agonist, ICI 204448, Evokes Hypothermia in Cold-Exposed Rats (2005) (5)
- Local, Controlled Delivery of Local Anesthetics In Vivo from Polymer - Xerogel Composites (2016) (5)
- Opioids II (1993) (5)
- Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation (2011) (5)
- Capsaicin and nitric oxide synthase inhibitor interact to evoke a hypothermic synergy (2006) (4)
- [d-Pen2,d-Pen5]enkephalin, the standard delta opioid agonist, induces morphine-like behaviors in mice (2005) (4)
- Differentiation of apomorphine from bromocriptine, piribidel and TRH by chronic administration in rats (2004) (4)
- Proceedings: Analgesics and rotational behaviour in rats with unilateral substantia nigra lesions. Effects in the presence and absence of (+)-amphetamine. (1975) (4)
- Effect of midbrain raphe lesion and of 6-hydroxydopamine on the antinociceptive action of buprenorphine in rats. (1974) (4)
- Proceedings: Potentiation of picrotoxin-induced convulsions in mice by antidepressants. Specificity of the effect. (1974) (4)
- Chemokine receptor antagonists enhance the antinociceptive activity of oxycodone and meperidine on incisional pain in rats. (2019) (4)
- Mechanisms of opioid activity (1992) (3)
- Ethylketocyclazocine and morphine: A comparison of their efficacies on gastrointestinal transit (GIT) after central and peripheral administration to rats (1981) (3)
- Extraction and measurement of morphine: correlation of brain level and s.c. dose in drug-naive and morphine-tolerant rats. (1982) (3)
- Effects of intracerebroventricular beta-funaltrexamine on mu and delta opioid receptors in the rat: dichotomy between binding and antinociception. (1991) (3)
- Nmda antagonists and win 55212 2, a cannabinoid agonist, interact to produce synergistic hypothermia (2002) (3)
- Chemokine receptor antagonists enhance morphine's antinociceptive effect but not respiratory depression. (2021) (3)
- Effects of Lidocaine or Capsaicin on Scratching and Grooming Induced in Mice by Centrally or Peripherally Injected Bombesin a (1988) (3)
- Failure of (+)-naloxone to accelerate feline colonic transit (1990) (3)
- THE EFFECT OF PROTOTYPE OPIATE RECEPTOR AGONISTS AND OPIOID PEPTIDES ON BODY TEMPERATURE AND BEHAVIOUR AFTER CENTRAL ADMINISTRATION TO CATS (1980) (3)
- Evidence for Three Distinct Peripheral Neurokinin Receptors Using a Putative Neurokinin B Antagonist (1987) (2)
- Evidence for the role of conditioning in the development of tolerance to morphine-induced inhibition of gastrointestinal motility in rats (1982) (2)
- In vivo and in vitro studies with agents that cause quasi-morphine withdrawal syndromes. (1982) (2)
- Characterization of 5 compounds that induce 'wet-dog' shakes in rats (1980) (2)
- 5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats (2008) (2)
- The antagonism by naloxone of agents that interact with dopaminergic neurones. (1978) (2)
- Proceedings: Inability of antidepressants and morphine to reverse reserpine-induced hypothermia in adrenalectomized mice. (1972) (2)
- Pharmacological profile of ICI 216140, a novel bombesin antagonist (1990) (2)
- Effect of morphine antagonists on drug-induced hypothermia in mice and rats (1976) (2)
- ICI 154,129, a delta-opioid receptor antagonist raises seizure threshold in rats. (1984) (2)
- INVOlVeMeNT Of PrOTeINASe-AcTIVATeD recePTOr-2 IN SPONTANeOUS ScrATchING Of MIce WITh ATOPy-lIKe DerMATITIS ( P 15 ) (2007) (1)
- Eeg and behavioral studies with zomepirac sodium in rats (1981) (1)
- Differential effects of opioids on flurothyl seizure thresholds in rats. (1979) (1)
- Involvement of a peripheral component in the antinociceptive effects of opioids in a model of tonic pain. (1990) (1)
- Itching-like behavior: A common effect of the kappa opioid receptor antagonist 5′-guanidinonaltrindole and the biased kappa opioid receptor agonist 6′-guanidinonaltrindole in mice (2021) (1)
- FURTHER STUDIES ON THE KAPPA OPIOID-BOMBESIN INTERFACE (1995) (1)
- Use of the formalin test in rats as a tonic pain model (1988) (1)
- Comparison of PD 117302, a kappa agonist, and morphine on colonic transit and formalin-induced pain in rats. (1989) (1)
- Differential efficacies of proposed kappa agonists on gastrointestinal transit in mice (1983) (1)
- Estimation of half life of ICV administered naloxone in rats using the time-dependent form of the equation for competitive antagonism (1981) (1)
- TIPS-February 1986 In-vivo studies on kappa opioid receptors (2003) (0)
- Central infusion of rats with agents selective for different types of opioid receptor. (1986) (0)
- Cross-tolerance between morphine (M) and ethyl-ketocyclazocine (EK) using analgesia and gastrointestinal motility as endpoints in rats (1982) (0)
- The effect of acute doses of buprenorphine on concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MH PG) in the rat forebrain The stimulated release of dopamine-L3-hydroxylase from intact organs of normo- and hypertensive rats (2006) (0)
- Lysergic Acid Diethylamide Antagonizes Shaking in Rats by Five Chemically Different Compounds (0)
- Humanchorionic gonadotrophin andsport (1991) (0)
- Treg apoptosis accelerates vasculitis 7144 down-regulation of endogenous TCTP expression by antisense results in the increase of T cell apoptosis (2008) (0)
- JPET #183905 1 Sex Difference in Kappa Opioid Receptor (KOPR)-Mediated Behaviors and Brain Region KOPR level and KOPR-mediated [S]GTPS Binding in the Guinea Pig (2011) (0)
- Correction (2015) (0)
- antinociceptive properties of [D-Ala2, NMPhe4, Gly-ol]-enkephalin (DAGO) in tests of acute and tonic pain in mice. (1988) (0)
- ULTRAVIOLET RADIATION-INDUCED NOCICEPTION: BASIS FOR A NOVEL ANALGESIC TEST IN MICE (1980) (0)
- Behavioral studies with ACTH (1-24), β-endorphin, bombesin and TRH: endogenous stimulants of grooming and shaking in rats (1981) (0)
- An in vivo pharmacological analysis of benzomorphan binding sites in rats. (1984) (0)
- Morphine receptor dissociation constant (K(A)) and morphine efficacy determined by the charcoal meal test in rats (1981) (0)
- Peripheral kappa-opioid agonist, ICI 204448, evokes hypothermia in cold-exposed rats. (2005) (0)
- EEG ALTERATIONS INDUCED IN RATS BY ETHYLKETOCYCLAZOCINE, CYCLAZOCINE, AND MORPHINE: THE DIFFERENTIAL EFFECTS OF NALOXONE (1980) (0)
- T1309 Evaluation of Interactions Between Morphine and Metoclopramide (2008) (0)
- 644 – THE ANIMAL PHARMACOLOGY OF BUPRENORPHINE : A NEW NARCOTIC ANTAGONIST ANALGESIC (1977) (0)
- Local, Controlled Delivery of Local Anesthetics In Vivo from Polymer - Xerogel Composites (2015) (0)
- Abstract 5472: Expression Of TCTP Antisense In CD4+CD25High Regulatory T Cells Weakens The Cell Survival And Aggravates Vascular Inflammation (2008) (0)
- Effects of bombesin, neuromedin B and neuromedin C on temperature and behaviour of rats (1985) (0)
- Potency of supraspinal & spinal selective opioids in the mouse writhing test (1985) (0)
- Involvement of kappa opioid receptors in the neuroadaptation of rats to buprenorphine (1994) (0)
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Alan Cowan is affiliated with the following schools:
