Alan Grossman
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Chemistry
Alan Grossman's Degrees
- Masters Chemical Engineering Stanford University
Why Is Alan Grossman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alan D. Grossman, is an American microbiologist; he is currently the Praecis Professor of Biology and served head of the Department of Biology at the Massachusetts Institute of Technology from 2014-2022. He is a member of the National Academy of Sciences and the American Academy of Arts & Sciences.
Alan Grossman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulation of noise in the expression of a single gene (2002) (1624)
- A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli. (1989) (762)
- The htpR gene product of E. coli is a sigma factor for heat-shock promoters (1984) (554)
- Localization of bacterial DNA polymerase: evidence for a factory model of replication. (1998) (521)
- Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis. (1995) (449)
- Biochemical and genetic characterization of a competence pheromone from B. subtilis (1994) (441)
- Identification and Characterization of a Bacterial Chromosome Partitioning Site (1998) (403)
- spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis (1994) (374)
- Bipolar Localization of the Replication Origin Regions of Chromosomes in Vegetative and Sporulating Cells of B. subtilis (1997) (365)
- Using buoyant mass to measure the growth of single cells (2010) (360)
- Integrative and Conjugative Elements (ICEs): What They Do and How They Work. (2015) (346)
- Genome-Wide Analysis of the Stationary-Phase Sigma Factor (Sigma-H) Regulon of Bacillus subtilis (2002) (331)
- Characterization of a prokaryotic SMC protein involved in chromosome partitioning. (1998) (288)
- Purification and characterization of an extracellular peptide factor that affects two different developmental pathways in Bacillus subtilis. (1996) (279)
- Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor. (1993) (274)
- Nutritional Control of Elongation of DNA Replication by (p)ppGpp (2007) (272)
- Bipolar localization of a chromosome partition protein in Bacillus subtilis. (1997) (263)
- The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence (1991) (256)
- Identification of Catabolite Repression as a Physiological Regulator of Biofilm Formation by Bacillus subtilis by Use of DNA Microarrays (2003) (252)
- Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis (2003) (250)
- Movement of replicating DNA through a stationary replisome. (2000) (245)
- Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis. (1999) (243)
- An Exported Peptide Functions Intracellularly to Contribute to Cell Density Signaling in B. subtilis (1997) (240)
- Regulation of a Bacillus subtilis mobile genetic element by intercellular signaling and the global DNA damage response. (2005) (238)
- Identification and characterization of genes controlled by the sporulation-regulatory gene spo0H in Bacillus subtilis (1989) (228)
- srfA is an operon required for surfactin production, competence development, and efficient sporulation in Bacillus subtilis (1991) (215)
- Chromosome arrangement within a bacterium (1998) (208)
- Replication Initiation Proteins Regulate a Developmental Checkpoint in Bacillus subtilis (2001) (207)
- Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis. (1995) (201)
- Isolation and characterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis (1995) (201)
- Extracellular control of spore formation in Bacillus subtilis. (1988) (200)
- Identification of AbrB‐regulated genes involved in biofilm formation by Bacillus subtilis (2004) (199)
- Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli. (1987) (195)
- Who's competent and when: regulation of natural genetic competence in bacteria. (1996) (189)
- Control of development by altered localization of a transcription factor in B. subtilis. (1999) (186)
- Replication–transcription conflicts in bacteria (2012) (181)
- Genetic Composition of the Bacillus subtilis SOS System (2005) (180)
- The ins and outs of peptide signaling. (1998) (178)
- The chromosome partitioning proteins Soj (ParA) and Spo0J (ParB) contribute to accurate chromosome partitioning, separation of replicated sister origins, and regulation of replication initiation in Bacillus subtilis (2006) (172)
- Gene expression in single cells of Bacillus subtilis: evidence that a threshold mechanism controls the initiation of sporulation (1994) (171)
- Whole‐genome analysis of the chromosome partitioning and sporulation protein Spo0J (ParB) reveals spreading and origin‐distal sites on the Bacillus subtilis chromosome (2007) (167)
- Co-directional replication-transcription conflicts lead to replication restart (2010) (162)
- FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. (2003) (161)
- Cytoplasmic degradation of ssrA‐tagged proteins (2005) (159)
- The extrusion-capture model for chromosome partitioning in bacteria. (2001) (154)
- A gene regulating the heat shock response in Escherichia coli also affects proteolysis. (1984) (148)
- Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum‐sensing transcription factor ComA in Bacillus subtilis (2005) (141)
- Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase (1984) (135)
- Characterization of comQ and comX, Two Genes Required for Production of ComX Pheromone in Bacillus subtilis (2002) (127)
- In Vivo Effects of Sporulation Kinases on Mutant Spo0A Proteins in Bacillus subtilis (2001) (127)
- Beta clamp directs localization of mismatch repair in Bacillus subtilis. (2008) (121)
- Stringent response in Escherichia coli induces expression of heat shock proteins. (1985) (120)
- Different roles for KinA, KinB, and KinC in the initiation of sporulation in Bacillus subtilis (1995) (118)
- Structure and mechanism of action of Sda, an inhibitor of the histidine kinases that regulate initiation of sporulation in Bacillus subtilis. (2004) (118)
- An Autoregulatory Circuit Affecting Peptide Signaling in Bacillus subtilis (1999) (114)
- Autonomous plasmid‐like replication of a conjugative transposon (2010) (112)
- A conserved anti‐repressor controls horizontal gene transfer by proteolysis (2008) (111)
- Effects of the Chromosome Partitioning Protein Spo0J (ParB) on oriC Positioning and Replication Initiation in Bacillus subtilis (2003) (111)
- A transcriptional response to replication status mediated by the conserved bacterial replication protein DnaA. (2005) (110)
- Enabling Genetic Analysis of Diverse Bacteria with Mobile-CRISPRi (2018) (109)
- Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria (2018) (105)
- The Transcriptional Regulator Rok Binds A+T-Rich DNA and Is Involved in Repression of a Mobile Genetic Element in Bacillus subtilis (2010) (101)
- Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis (2007) (101)
- Genome-wide coorientation of replication and transcription reduces adverse effects on replication in Bacillus subtilis (2007) (101)
- Visualization of mismatch repair in bacterial cells. (2001) (99)
- Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis (1993) (99)
- Characterization of the Global Transcriptional Responses to Different Types of DNA Damage and Disruption of Replication in Bacillus subtilis (2006) (97)
- Modulation of the ComA-Dependent Quorum Response in Bacillus subtilis by Multiple Rap Proteins and Phr Peptides (2006) (95)
- Possible role for the essential GTP-binding protein Obg in regulating the initiation of sporulation in Bacillus subtilis (1995) (89)
- Control of Sporulation Gene Expression in Bacillus subtilis by the Chromosome Partitioning Proteins Soj (ParA) and Spo0J (ParB) (2000) (89)
- Control of DNA replication initiation by recruitment of an essential initiation protein to the membrane of Bacillus subtilis (2004) (87)
- Subcellular localization of the Bacillus subtilis structural maintenance of chromosomes (SMC) protein (2002) (86)
- Spatial and temporal organization of the Bacillus subtilis replication cycle (2006) (85)
- Identification and characterization of int (integrase), xis (excisionase) and chromosomal attachment sites of the integrative and conjugative element ICEBs1 of Bacillus subtilis (2007) (84)
- Identification of the Origin of Transfer (oriT) and DNA Relaxase Required for Conjugation of the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis (2007) (83)
- Effects of replication termination mutants on chromosome partitioning in Bacillus subtilis. (2001) (82)
- The Bacillus subtilis Conjugative Transposon ICEBs1 Mobilizes Plasmids Lacking Dedicated Mobilization Functions (2012) (81)
- Inducible protein degradation in Bacillus subtilis using heterologous peptide tags and adaptor proteins to target substrates to the protease ClpXP (2008) (78)
- Ordered association of helicase loader proteins with the Bacillus subtilis origin of replication in vivo (2009) (77)
- Mutations in the Lon gene of E. coli K12 phenotypically suppress a mutation in the sigma subunit of RNA polymerase (1983) (75)
- Effect of minCD on FtsZ Ring Position and Polar Septation in Bacillus subtilis (1998) (74)
- Synthetic Lethal Phenotypes Caused by Mutations Affecting Chromosome Partitioning in Bacillus subtilis (1999) (72)
- A developmental checkpoint couples the initiation of sporulation to DNA replication in Bacillus subtilis. (1994) (72)
- Control of a Family of Phosphatase Regulatory Genes (phr) by the Alternate Sigma Factor Sigma-H ofBacillus subtilis (2001) (70)
- Comparison of Responses to Double-Strand Breaks between Escherichia coli and Bacillus subtilis Reveals Different Requirements for SOS Induction (2008) (69)
- Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis. (1995) (69)
- Polymer Stability Plays an Important Role in the Positional Regulation of FtsZ (2001) (68)
- Efficient Gene Transfer in Bacterial Cell Chains (2011) (66)
- Structural Maintenance of Chromosomes Protein of Bacillussubtilis Affects Supercoiling In Vivo (2002) (63)
- Coupling between gene expression and DNA synthesis early during development in Bacillus subtilis. (1992) (62)
- Integration of developmental signals and the initiation of sporulation in B. subtilis (1991) (62)
- Altering the level and regulation of the major sigma subunit of RNA polymerase affects gene expression and development in Bacillus subtilis (1996) (59)
- Replication is required for the RecA localization response to DNA damage in Bacillus subtilis (2007) (57)
- Sequence and properties of mecA, a negative regulator of genetic competence in Bacillus subtilis (1993) (54)
- Clp and Lon Proteases Occupy Distinct Subcellular Positions in Bacillus subtilis (2008) (53)
- Regulation of Horizontal Gene Transfer in Bacillus subtilis by Activation of a Conserved Site-Specific Protease (2010) (53)
- Interactions among mutations that cause altered timing of gene expression during sporulation in Bacillus subtilis (1992) (49)
- Localization of UvrA and Effect of DNA Damage on the Chromosome of Bacillus subtilis (2002) (48)
- Mutations in the rpoH (htpR) gene of Escherichia coli K-12 phenotypically suppress a temperature-sensitive mutant defective in the sigma 70 subunit of RNA polymerase (1985) (48)
- Polar Positioning of a Conjugation Protein from the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis (2009) (48)
- Primosomal Proteins DnaD and DnaB Are Recruited to Chromosomal Regions Bound by DnaA in Bacillus subtilis (2010) (47)
- The Sporulation Protein SirA Inhibits the Binding of DnaA to the Origin of Replication by Contacting a Patch of Clustered Amino Acids (2011) (47)
- YabA of Bacillus subtilis controls DnaA‐mediated replication initiation but not the transcriptional response to replication stress (2009) (46)
- Subcellular positioning of the origin region of the Bacillus subtilis chromosome is independent of sequences within oriC, the site of replication initiation, and the replication initiator DnaA (2007) (45)
- Activation of spo0A transcription by sigma H is necessary for sporulation but not for competence in Bacillus subtilis (1994) (45)
- Regulation of the Initiation of Endospore Formation in Bacillus subtilis (2000) (44)
- A Conserved Helicase Processivity Factor Is Needed for Conjugation and Replication of an Integrative and Conjugative Element (2013) (42)
- Identification of host genes that affect acquisition of an integrative and conjugative element in Bacillus subtilis (2014) (40)
- Complete Genome Sequences of Bacillus subtilis subsp. subtilis Laboratory Strains JH642 (AG174) and AG1839 (2014) (40)
- Selective Pressures to Maintain Attachment Site Specificity of Integrative and Conjugative Elements (2013) (40)
- The Bifunctional Cell Wall Hydrolase CwlT Is Needed for Conjugation of the Integrative and Conjugative Element ICEBs1 in Bacillus subtilis and B. anthracis (2014) (40)
- Autonomous Replication of the Conjugative Transposon Tn916 (2016) (37)
- Control of the replication initiator DnaA by an anti‐cooperativity factor (2011) (36)
- Dynamic Association of the Replication Initiator and Transcription Factor DnaA with the Bacillus subtilis Chromosome during Replication Stress (2008) (34)
- Deletion of the Bacillus subtilis isocitrate dehydrogenase gene causes a block at stage I of sporulation (1997) (34)
- Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell. (1984) (32)
- Cell cycle and sporulation in Bacillus subtilis. (1998) (31)
- Analysis of non-polar deletion mutations in the genes of the spo0K (opp) operon of Bacillus subtilis. (1997) (29)
- An Open Letter to Elias Zerhouni (2005) (29)
- The Primosomal Protein DnaD Inhibits Cooperative DNA Binding by the Replication Initiator DnaA in Bacillus subtilis (2012) (29)
- When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD (2010) (29)
- Identification of a Single Strand Origin of Replication in the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis (2015) (26)
- A Mobile Element in mutS Drives Hypermutation in a Marine Vibrio (2017) (26)
- Control of Initiation of Sporulation by Replication Initiation Genes in Bacillus subtilis (2000) (25)
- A degenerate tripartite DNA-binding site required for activation of ComA-dependent quorum response gene expression in Bacillus subtilis. (2008) (25)
- Critical Components of the Conjugation Machinery of the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis (2015) (24)
- Isolation and Characterization of Mutants of the Bacillus subtilis Oligopeptide Permease with Altered Specificity of Oligopeptide Transport (2003) (23)
- In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA (2015) (22)
- Multicopy Plasmids Affect Replisome Positioning in Bacillus subtilis (2004) (22)
- Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid‐associated protein Rok in Bacillus subtilis (2017) (21)
- Identification of host genes that affect acquisition of an integrative and conjugative element in Bacillus subtilis (2014) (20)
- Cell cycle: The bacterial approach to coordination (1998) (18)
- Identification, characterization and benefits of an exclusion system in an integrative and conjugative element of Bacillus subtilis (2019) (17)
- SOS Induction in a Subpopulation of Structural Maintenance of Chromosome (Smc) Mutant Cells in Bacillus subtilis (2007) (17)
- A mobile genetic element increases bacterial host fitness by manipulating development (2020) (16)
- Suppressors of a spo0A missense mutation and their effects on sporulation in Bacillus subtilis. (1992) (16)
- Genetic networks controlled by the bacterial replication initiator and transcription factor DnaA in Bacillus subtilis (2017) (16)
- The Composition of the Cell Envelope Affects Conjugation in Bacillus subtilis (2016) (15)
- CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA (2021) (14)
- Interactions between mobile genetic elements: An anti-phage gene in an integrative and conjugative element protects host cells from predation by a temperate bacteriophage (2022) (13)
- Chromosome Replication and Segregation (2002) (12)
- Intragenic and Extragenic Suppressors of Temperature Sensitive Mutations in the Replication Initiation Genes dnaD and dnaB of Bacillus subtilis (2009) (12)
- A regulatory switch involving a Clp ATPase. (1997) (11)
- A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli (1989) (11)
- DNA-related conditions controlling the initiation of sporulation in Bacillus subtilis. (1994) (10)
- An integrative and conjugative element encodes an abortive infection system to protect host cells from predation by a bacteriophage (2020) (8)
- Analysis of LexA binding sites and transcriptomics in response to genotoxic stress in Leptospira interrogans (2016) (8)
- ROLE OF EXTRACELLULAR FACTORS IN THE CONTROL OF SPORULATION IN BACILLUS SUBTILIS (1988) (6)
- Complete Genome Sequence of Bacillus subtilis Strain CU1050, Which Is Sensitive to Phage SPβ (2016) (6)
- Extracellular Peptide Signaling and Quorum Responses in Development, Self-Recognition, and Horizontal Gene Transfer in Bacillus subtilis (2008) (5)
- Biology and engineering of integrative and conjugative elements: Construction and analyses of hybrid ICEs reveal element functions that affect species-specific efficiencies (2021) (5)
- Characterization of csh203::Tn917lac, a mutation in Bacillus subtilis that makes the sporulation sigma factor sigma-H essential for normal vegetative growth (1995) (4)
- Regulation of the Heat-Shock Response in Escherichia coli (1987) (4)
- Mobile-CRISPRi: Enabling Genetic Analysis of Diverse Bacteria (2018) (4)
- Critical components of the conjugation machinery of the integrative and conjugative 1 element ICE Bs 1 of Bacillus subtilis 2 3 Running title : Conjugation machinery of ICE Bs 1 4 5 6 (2015) (4)
- Activation of the integrative and conjugative element Tn916 causes growth arrest and death of host bacteria (2022) (3)
- Regulation of cyclic AMP synthesis in Escherichia coli K-12: effects of the rpoD800 sigma mutation, glucose, and chloramphenicol (1984) (2)
- Specificity and Selective Advantage of an Exclusion System in the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis (2021) (2)
- The primosomal protein DnaD inhibits cooperative DNA binding by the 2 replication initiator DnaA in Bacillus subtilis 3 4 5 (2012) (1)
- Beneficial and detrimental genes in the cellular response to replication arrest (2021) (1)
- Spatio-temporal control of DNA replication by the pneumococcal cell cycle regulator CcrZ (2019) (1)
- normal vegetative growth . sporulation sigma factor sigma-H essential for mutation in Bacillus subtilis that makes the Characterization of csh 203 : : Tn 917 lac , a (1995) (1)
- for genetic mapping of Escherichia coli. linked alternating antibiotic resistance elements A collection of strains containing genetically (2013) (1)
- Multiple mechanisms for overcoming lethal over‐initiation of DNA replication (2021) (1)
- A CRISPR interference screen reveals a role for cell wall teichoic acids in conjugation in Bacillus subtilis (2021) (1)
- Identification of a Single Strand Origin of Replication in the Integrative and Conjugative Element ICEBs 1 of Bacillus subtilis Citation (2015) (0)
- Abstracts of papers presented at the 2000 Meeting on Molecular Genetics of Bacteria & Phages, August 22-August 27, 2000 (2000) (0)
- Polar positioning of a conjugation protein from the integrative and 2 conjugative element ICE Bs 1 of Bacillus subtilis 3 4 (2009) (0)
- NOTES Activation ofspoOATranscription byuFHIsNecessary for Sporulation butNotforCompetence inBacillus subtilis (1994) (0)
- Table of Contents (1994) (0)
- Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid-associated protein Rok in (2016) (0)
- Efficient Gene Transfer in Bacterial Cell Chains 2011 (2011) (0)
- efficient sporulation in Bacillus subtilis. production, competence development, and srfA is an operon required for surfactin (2013) (0)
- Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria (2018) (0)
- ( ParB ) Partitioning Proteins Soj ( ParA ) and Spo 0 J by the Chromosome Bacillus subtilis Control of Sporulation Gene Expression in (2000) (0)
- TnSmu1 is a functional integrative and conjugative element in Streptococcus mutans that when expressed causes growth arrest of host bacteria (2022) (0)
- Structure of the Sda antikinase (2004) (0)
- Timing of integration into the chromosome is critical for the fitness of an integrative and conjugative element and its bacterial host (2022) (0)
- sigma mutation, glucose, and chloramphenicol. Escherichia coli K-12: effects of the rpoD800 Regulation of cyclic AMP synthesis in (2013) (0)
- chromosome?partitioning Characterization of a prokaryotic SMC protein involved in (2011) (0)
- through the Spo 0 A transcription factor . Integration of multiple developmental signals in Bacillus subtilis (2007) (0)
- Structure and Mechanism of Action of Sda , an Inhibitor of the Histidine Kinases that Regulate Initiation of Sporulation in Bacillus subtilis Citation (2004) (0)
- Expression during Sporulation in Bacillus subtilis (0)
- ThespoOKLocusofBacillus subtilis IsHomologous tothe Oligopeptide Permease LocusandIsRequired for Sporulation andCompetence (1991) (0)
- Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi (2019) (0)
- Target search by an imported conjugative DNA element for a unique integration site along a bacterial chromosome during horizontal gene transfer (2023) (0)
- Shigeki Moriya and subtilis Bacillus and Replication Initiation in Positioning oriC Protein Spo 0 J ( ParB ) on Effects of the Chromosome Partitioning (2003) (0)
- Polymer Stability Plays an Important Role in the Positional Regulation of FtsZ (2001) (0)
- sporulation in Bacillus subtilis . protein Obg in regulating the initiation of Possible role for the essential GTP-binding (1995) (0)
- Effects of the mobile genetic element ICEBs1 on bacterial host fitness (2020) (0)
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