Alan Hall
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Biologist
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Biology
Alan Hall's Degrees
- Masters Biotechnology Stanford University
Why Is Alan Hall Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alan Hall FRS was a British cell biologist and a biology professor at the Sloan-Kettering Institute, where he was chair of the Cell Biology program. Hall was elected a Fellow of the Royal Society in 1999.
Alan Hall's Published Works
Published Works
- Rho GTPases and the actin cytoskeleton. (1998) (5341)
- The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors (1992) (4665)
- Rho GTPases in cell biology (2002) (4646)
- Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia (1995) (4531)
- The small GTP-binding protein rac regulates growth factor-induced membrane ruffling (1992) (3671)
- Rho GTPases: biochemistry and biology. (2005) (2935)
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive (2004) (2094)
- Rho GTPases and their effector proteins. (2000) (2034)
- Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement (1999) (1524)
- Cell migration: Rho GTPases lead the way. (2004) (1474)
- Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. (2002) (1296)
- An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 (1995) (1214)
- Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCζ (2001) (1033)
- Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. (1998) (1031)
- Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 (1991) (936)
- Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. (1997) (851)
- Ras and Rho GTPases A Family Reunion (2000) (840)
- The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts (1997) (802)
- Small GTP-binding proteins and the regulation of the actin cytoskeleton. (1994) (782)
- Rho GTPases and the control of cell behaviour. (2005) (779)
- Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity (2003) (770)
- The cellular functions of small GTP-binding proteins. (1990) (767)
- Axonal Remodeling and Synaptic Differentiation in the Cerebellum Is Regulated by WNT-7a Signaling (2000) (704)
- Microinjection of recombinant p21rho induces rapid changes in cell morphology (1990) (673)
- Interplay between Rac and Rho in the control of substrate contact dynamics (1999) (657)
- Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade (1996) (587)
- Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells (1995) (578)
- p27Kip1 modulates cell migration through the regulation of RhoA activation. (2004) (548)
- Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton. (2000) (529)
- Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3 (2000) (525)
- Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo (1998) (491)
- Signal transduction pathways regulating Rho‐mediated stress fibre formation: requirement for a tyrosine kinase. (1994) (482)
- Rho family GTPases. (2012) (481)
- The cytoskeleton and cancer (2009) (455)
- Signaling to Rho GTPases. (1999) (452)
- Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice. (1999) (444)
- Bcr encodes a GTPase-activating protein for p21rac (1991) (441)
- Activation of the small GTP-binding proteins rho and rac by growth factor receptors. (1995) (440)
- The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases (1995) (434)
- Post-translational modifications of p21rho proteins. (1992) (425)
- Rho and Ras GTPases in axon growth, guidance, and branching. (2010) (417)
- Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1 (1983) (409)
- Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility. (1995) (409)
- Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization (1997) (406)
- Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity. (1994) (397)
- Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott–Aldrich syndrome (1996) (395)
- Intracellular localization of the P21rho proteins (1992) (383)
- A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion (1998) (383)
- Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex (2001) (382)
- Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells (1999) (370)
- Wnt signaling pathways meet Rho GTPases. (2009) (366)
- Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis (2008) (350)
- Regulation of Cell Migration by the C2 Domain of the Tumor Suppressor PTEN (2004) (347)
- Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. (2001) (346)
- Cell polarity: Par6, aPKC and cytoskeletal crosstalk. (2003) (338)
- The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho (2000) (335)
- Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production (1986) (331)
- Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins (1997) (328)
- Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction. (1999) (321)
- The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product (1988) (313)
- Cdc42 and Par6–PKCζ regulate the spatially localized association of Dlg1 and APC to control cell polarization (2005) (306)
- Involvement of the Arp2/3 complex in phagocytosis mediated by FcγR or CR3 (2000) (303)
- Rac/Cdc42 and p65PAK Regulate the Microtubule-destabilizing Protein Stathmin through Phosphorylation at Serine 16* (2001) (303)
- Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways (1996) (298)
- Rho: a connection between membrane receptor signalling and the cytoskeleton. (1996) (295)
- Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle. (1996) (295)
- Rho GTPases in transformation and metastasis. (2002) (278)
- A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo (2006) (271)
- The MAP kinase kinase kinase MLK2 co‐localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3 (1998) (267)
- Dynamic fatty acylation of p21N‐ras. (1987) (262)
- A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos (1997) (261)
- The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3. (1989) (259)
- Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways (2005) (259)
- GAPs for rho-related GTPases. (1994) (253)
- IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells (1999) (252)
- The GTPase Rap1 controls functional activation of macrophage integrin αMβ2 by LPS and other inflammatory mediators (2000) (251)
- rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo. (1993) (245)
- Regulation and function of the Rho subfamily of small GTPases. (1994) (244)
- G Proteins and Small GTPases: Distant Relatives Keep in Touch (1998) (231)
- Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release (2006) (228)
- Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases (1996) (225)
- Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF alpha-receptors. (1996) (224)
- Ras-related GTPases and the cytoskeleton. (1992) (222)
- A new Rac target POSH is an SH3‐containing scaffold protein involved in the JNK and NF‐κB signalling pathways (1998) (220)
- Rac mediates growth factor-induced arachidonic acid release (1995) (216)
- Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. (1989) (213)
- Oligodendrocyte lineage and the motor neuron connection (2000) (201)
- Rac Mediates Cytoskeletal Rearrangements and Increased Cell Motility Induced by Urokinase-Type Plasminogen Activator Receptor Binding to Vitronectin (2001) (199)
- Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho (2001) (198)
- Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity (2007) (195)
- Purification of recombinant Rho/Rac/G25K from Escherichia coli. (1995) (193)
- A novel type of myosin implicated in signalling by rho family GTPases. (1995) (189)
- The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. (2001) (185)
- Valproate Regulates GSK-3-Mediated Axonal Remodeling and Synapsin I Clustering in Developing Neurons (2002) (175)
- Rac regulates endothelial morphogenesis and capillary assembly. (2002) (172)
- The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo (2008) (169)
- Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases. (1994) (158)
- Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho. (1992) (156)
- Activation of the small GTPase Cdc42 by the inflammatory cytokines TNF(alpha) and IL-1, and by the Epstein-Barr virus transforming protein LMP1. (1999) (155)
- Origins of spinal cord oligodendrocytes: possible developmental and evolutionary relationships with motor neurons. (1997) (155)
- The effect of Mg2+ on the guanine nucleotide exchange rate of p21N-ras. (1986) (153)
- A biochemical function for ras--at last. (1994) (153)
- Direct Involvement of the Small GTP-binding Protein Rho in lbc Oncogene Function (*) (1995) (152)
- Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins (1994) (147)
- The GTPase Rho has a critical regulatory role in thymus development (1997) (143)
- Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK (2003) (142)
- Botulinum ADP-ribosyltransferase C3: a new tool to study low molecular weight GTP-binding proteins. (1989) (142)
- Identification of midbrain floor plate radial glia‐like cells as dopaminergic progenitors (2008) (138)
- Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates. (1995) (135)
- Par6B and Atypical PKC Regulate Mitotic Spindle Orientation during Epithelial Morphogenesis* (2011) (132)
- The Rho's progress: a potential role during neuritogenesis for the Rho family of GTPases (1995) (127)
- PRK1 Is Targeted to Endosomes by the Small GTPase, RhoB* (1998) (126)
- Schwann cells induce cancer cell dispersion and invasion. (2016) (125)
- Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. (2009) (125)
- Rac GTPase interacts with GAPs and target proteins through multiple effector sites. (1995) (125)
- Different Regions of Rho Determine Rho-selective Binding of Different Classes of Rho Target Molecules* (1998) (124)
- Signal transduction through small GTPases—A tale of two GAPs (1992) (124)
- Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3. (2000) (124)
- p190-B, a New Member of the Rho GAP Family, and Rho Are Induced to Cluster after Integrin Cross-linking (*) (1995) (121)
- Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility. (1999) (120)
- Vav regulates activation of Rac but not Cdc42 during FcγR-mediated phagocytosis (2002) (116)
- Ras-related proteins. (1993) (116)
- Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo (2008) (116)
- The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. (2008) (114)
- Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3β) independently of Akt/PKB serine phosphorylation (2006) (113)
- Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts. (1997) (111)
- A novel role for RhoGDI as an inhibitor of GAP proteins. (1993) (110)
- Ral GTPases regulate neurite branching through GAP-43 and the exocyst complex (2005) (110)
- Kinetic analysis of the hydrolysis of GTP by p21N-ras. The basal GTPase mechanism. (1988) (109)
- Mechanism of activation of an N‐ras gene in the human fibrosarcoma cell line HT1080. (1984) (109)
- The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators. (2000) (108)
- Stimulation of phosphatidylcholine hydrolysis, diacylglycerol release, and arachidonic acid production by oncogenic ras is a consequence of protein kinase C activation. (1989) (108)
- Lipopolysaccharide-Induced Activation of β2-Integrin Function in Macrophages Requires Irak Kinase Activity, p38 Mitogen- Activated Protein Kinase, and the Rap1 GTPase (2001) (107)
- Cellular responses to extracellular guidance cues (2010) (106)
- Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis (2007) (105)
- Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase (1997) (104)
- Analysis of R-Ras signalling pathways. (2001) (103)
- Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells (1987) (101)
- Rac1-Dependent Collective Cell Migration Is Required for Specification of the Anterior-Posterior Body Axis of the Mouse (2010) (101)
- The Activity of the Plexin-A1 Receptor Is Regulated by Rac* (2004) (98)
- Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas. (2011) (97)
- Myosin-IXA Regulates Collective Epithelial Cell Migration by Targeting RhoGAP Activity to Cell-Cell Junctions (2012) (97)
- A transforming gene present in human sarcoma cell lines (1982) (97)
- Human N-ras: cDNA cloning and gene structure. (1985) (96)
- Scrape-loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphoinositide hydrolysis. (1989) (94)
- Biochemical and biological properties of the human N-ras p21 protein (1987) (94)
- ALS2/Alsin Regulates Rac-PAK Signaling and Neurite Outgrowth* (2005) (93)
- Association of CNK1 with Rho Guanine Nucleotide Exchange Factors Controls Signaling Specificity Downstream of Rho (2005) (89)
- DLC1: a significant GAP in the cancer genome. (2008) (89)
- Human CNK1 Acts as a Scaffold Protein, Linking Rho and Ras Signal Transduction Pathways (2004) (89)
- The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. (2007) (84)
- Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease (1996) (84)
- CdGAP, a Novel Proline-rich GTPase-activating Protein for Cdc42 and Rac* (1998) (84)
- Different structural organization of Ras and Rho effector domains. (1993) (84)
- The Rho Exchange Factor Net1 Is Regulated by Nuclear Sequestration* (2002) (83)
- Ultrastructural localization of ras-related proteins using epitope-tagged plasmids. (1995) (79)
- Rho GTPases* (1998) (76)
- 14-3-3 Proteins: Hot numbers in signal transduction (1995) (76)
- Cdc42 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells through PAK4 and Par6B (2010) (72)
- Aluminium fluoride associates with the small guanine nucleotide binding proteins (1997) (71)
- Mitosis can drive cell cannibalism through entosis (2017) (69)
- Distinct roles for DH and PH domains in the Lbc oncogene (1997) (69)
- Directed selective pressure on a β-lactamase to analyse molecular changes involved in development of enzyme function (1976) (68)
- R-ras interacts with rasGAP, neurofibromin and c-raf but does not regulate cell growth or differentiation. (1994) (67)
- Transformation and stimulation of DNA synthesis in NIH‐3T3 cells are a titratable function of normal p21N‐ras expression. (1986) (63)
- Inhibition by phospholipids of the interaction between R-ras, rho, and their GTPase-activating proteins (1989) (62)
- Cellular responses regulated by rho-related small GTP-binding proteins. (1993) (60)
- Regulation of the actin cytoskeleton, integrins and cell growth by the Rho family of small GTPases. (1996) (59)
- p21H‐ras‐induced morphological transformation and increases in c‐myc expression are independent of functional protein kinase C. (1989) (57)
- Stabilization of the p53 transformation-related protein in mouse fibrosarcoma cell lines: effects of protein sequence and intracellular environment (1989) (55)
- The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells (2010) (53)
- Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis. (2002) (52)
- Activated Gαq family members induce Rho GTPase activation and Rho‐dependent actin filament assembly (2002) (52)
- K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc (2012) (52)
- Ras (proto)oncogene induces N‐linked carbohydrate modification: temporal relationship with induction of invasive potential. (1988) (52)
- Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium (2009) (50)
- The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype (2019) (50)
- Intracellular Localization of the P 2 lrh ~ Proteins (1992) (47)
- Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon. (1985) (45)
- LKB1 Controls Human Bronchial Epithelial Morphogenesis through p114RhoGEF-Dependent RhoA Activation (2013) (44)
- Stimulation of phosphatidylcholine breakdown and diacylglycerol production by growth factors in Swiss-3T3 cells. (1989) (44)
- Mutant but not normal p21 ras elevates inositol phospholipid breakdown in two different cell systems. (1988) (43)
- Microarray Analyses Support a Role for Nurr1 in Resistance to Oxidative Stress and Neuronal Differentiation in Neural Stem Cells (2007) (43)
- APC nuclear membrane association and microtubule polarity (2008) (40)
- Activation of G1 Progression, JNK Mitogen-activated Protein Kinase, and Actin Filament Assembly by the Exchange Factor FGD1* (1998) (40)
- GSK-3β sets Snail's pace (2004) (40)
- β-Pix directs collective migration of anterior visceral endoderm cells in the early mouse embryo (2014) (40)
- Expression and characterization of the Ha-ras p21 protein produced at high levels in the insect/baculovirus system. (1989) (40)
- Region‐specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons (2003) (37)
- Signal transduction pathways regulated by the Rho family of small GTPases. (1999) (34)
- ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas (2019) (31)
- A tumor suppressor role for srGAP3 in mammary epithelial cells (2013) (30)
- GTP-binding proteins (1991) (29)
- Localisation of the human N‐ras oncogene to chromosome 1cen ‐ p21 by in situ hybridisation. (1983) (29)
- The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration (2016) (28)
- Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration (2016) (28)
- Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases (2020) (28)
- Polarized Localization of Epithelial CXCL11 in Chronic Obstructive Pulmonary Disease and Mechanisms of T Cell Egression1 (2008) (28)
- LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity (2010) (27)
- Abnormal Development of Mouse Embryoid Bodies Lacking p27Kip1 Cell Cycle Regulator (2005) (26)
- Malignant transformation of murine fibroblasts by a human c-Ha-ras-1 oncogene does not require a functional epidermal growth factor receptor (1986) (26)
- Interaction of the human insulin receptor with the ras oncogene product p21 (1987) (26)
- The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells (2018) (25)
- Morphological alteration of Xenopus oocytes induced by valine‐14 p21rho depend on isoprenylation and are inhibited by Clostridium botulinum C3 ADP‐ribosyltranferase (1990) (24)
- Lithium and synaptic plasticity. (1999) (23)
- Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma (2022) (22)
- THE RHO GTPASE REGULATES PROTEIN KINASE ACTIVITY (1996) (22)
- All three human ras genes are expressed in a wide range of tissues. (1988) (22)
- In vitro binding assay for interactions of Rho and Rac with GTPase-activating proteins and effectors. (1995) (22)
- Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4. (2015) (21)
- Interaction of recombinant rho A GTP‐binding proteins with photoexcited rhodopsin (1990) (21)
- GSK-3beta sets Snail's pace. (2004) (21)
- Plexin-induced collapse assay in COS cells. (2006) (21)
- SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1 (2015) (21)
- Snails, swiss, and serum: The solution for Rac ‘n’ Rho (2004) (16)
- Bombesin stimulation of inositol 1,4,5-trisphosphate generation and intracellular calcium release is amplified in a cell line overexpressing the N-ras proto-oncogene. (1989) (16)
- Cdc42 regulates GSK3þ and adenomatous polyposis coli (APC)to control cell polarity (2003) (16)
- Partial transformation of mouse fibroblastic and epithelial cell lines with the v-myc oncogene. (1987) (15)
- Signal transduction by p21ras (1989) (14)
- Gαz Inhibits Serum Response Factor-Dependent Transcription by Inhibiting Rho Signaling (2004) (14)
- Rho GTPases and macrophage phagocytosis. (2000) (14)
- Morphological alterations of Xenopus oocytes induced by valine-14 p21rho depend on isoprenylation and are inhibited by Clostridium botulinum C3 ADP-ribosyltransferase. (1990) (14)
- Cell biology. Smurfing at the leading edge. (2003) (13)
- N-ras and human cancer. (1986) (13)
- Origins and early development of oligodendrocytes (1997) (12)
- The ras protein is not associated with exocytosis (1987) (12)
- Scrape-loaded p21ras down-regulates agonist-stimulated inositol phosphate production by a mechanism involving protein kinase C. (1989) (12)
- Function for Ras in sight (1992) (11)
- ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas. (2019) (10)
- Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity. (2004) (10)
- Tumour suppressors and the regulation of GTP-binding protein activity. (1993) (10)
- The role of N-ras p21 in the coupling of growth factor receptors to inositol phospholipid turnover. (1987) (9)
- Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion (2020) (9)
- N‐ras‐like sequences on chromosomes 9, 6 and 22 with a polymorphism at the chromosome 9 locus (1988) (8)
- Sphingosine 1-phosphate stimulates Rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3 T 3 fibroblasts (1997) (8)
- The adenosine monophosphate–activated protein kinase—vacuolar adenosine triphosphatase–pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells (2018) (8)
- Biomarkers of extracellular matrix formation are associated with acute-on-chronic liver failure (2021) (7)
- The AMPK-v-ATPase-pH axis : a key regulator of the pro-fibrogenic phenotype of human hepatic stellate cells (2018) (7)
- Analysis of mammalian ras effector function. (1988) (6)
- β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo (2020) (6)
- SOS 1 and Ras regulate epithelial tight junction formation in the human airway through EMP 1 (2014) (6)
- The Rho Target PRK 2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells ! (2010) (5)
- Alpha(E)-Catenin induces SRF-dependent transcriptional activity through its C-terminal region and is partly RhoA/ROCK-dependent. (2008) (5)
- TGFβ in the obese liver mediates conversion of NK cells to a less cytotoxic ILC1-like phenotype (2019) (5)
- Src Launches Vaccinia (2004) (5)
- Methods in Enzymology: Preface (2006) (4)
- AICAR and Compound C negatively modulate HCC-induced primary human hepatic stellate cell activation in vitro. (2021) (4)
- Small GTP-binding proteins--a new family of biologic regulators. (1992) (3)
- The Lipopolysaccharide-Sensing Caspase(s)-4/11 Are Activated in Cirrhosis and Are Causally Associated With Progression to Multi-Organ Injury (2021) (3)
- Clostridium botulinum C3 Exoenzyme and Studies on Rho Proteins (2008) (3)
- GTPases regulating membrane targeting and fusion (2005) (3)
- Smart Nanoparticles as Advanced Anti-Akt Kinase Delivery Systems for Pancreatic Cancer Therapy. (2021) (2)
- Kinetic Analysis of the Hydrolysis of GTP by p 21 N-" THE BASAL GTPase MECHANISM (2001) (2)
- Author response: Mitosis can drive cell cannibalism through entosis (2017) (2)
- The Function of the Mammalian Ras Proteins (1989) (1)
- rho and rho-Related Proteins (1993) (1)
- Small GTPases in disease (2008) (1)
- GTPases regulating membrane dynamics (2005) (1)
- Membrane association and transformation by p21 ras (1990) (1)
- Post-translational Modifications of p2 lrho Proteins* (2001) (1)
- Family values in signal transduction (1994) (1)
- Proteins involved in transport (1995) (1)
- Chapter 19 The role of ras in signal transduction (1997) (1)
- Origins and early development of oligodendrocyte precursor cells (1997) (0)
- Eye development. Function for Ras in sight. (1992) (0)
- The insulin receptor tyrosyl kinase fails to phosphorylate the guanine nucleotide regulatory proteins Ni, No and p21 (1986) (0)
- Supplemental Data Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells (2009) (0)
- Specification and growth of oligodendrocyte lineage cells (1998) (0)
- ReviewRas and Rho GTPases : A Family Reunion Rap 1 , is required to define the position of the new bud (2000) (0)
- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System (1989) (0)
- GTPases involved in vesicular traffic (2001) (0)
- Rho Family Gtpases Regulate Endothelial Morphogenesis and Capillary Assembly (2002) (0)
- Ras-genes and cellular transformation (1985) (0)
- Rho family GTPases Integrate Angiogenic Signalling Pathways (2002) (0)
- O06 Aminobisphosphonates enhance liver-resident gamma delta T cells for efficient targeting of hepatocellular carcinoma (2021) (0)
- Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization (2017) (0)
- Indirect interaction between p21N-ras and the adenyl cyclase system (1987) (0)
- Abstract A60: Kras-transformed Caco-2 cells establish a 3-D model of colon cancer (2011) (0)
- P053 Investigation of the origin of serum neutrophil gelatinase associated lipocalin (NGAL) following liver ischaemia reperfusion and resultant acute kidney injury in mice (2021) (0)
- The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells (2018) (0)
- Abstract 460: The role of Cdc42 in cancer cell perineural invasion (2012) (0)
- 1046 Targeting novel pathways in chronically activated T Cells prevents functional exhaustion (2022) (0)
- Transepithelial migration (TEpM) of T lymphocytes is an active multi-step process resulting in their luminal clearance (2006) (0)
- Abstract 4243: Oncogenic K-Ras transforms three-dimensional colon epithelia through upregulation of ERK-MAPK signaling (2012) (0)
- CHAPTER 237 – Rho Proteins and Their Effects on the Actin Cytoskeleton (2003) (0)
- G (cid:1) z Inhibits Serum Response Factor-Dependent Transcription by Inhibiting Rho Signaling (2004) (0)
- Cell migration : Rho GTPases lead the way Myrto Raftopoulou (2003) (0)
- P095 Newly discovered gut matrikines from Crohn’s disease intestinal tissue induce cell proliferation, activation and inflammatory response in intestinal myofibroblasts in vitro (2023) (0)
- Scrape-loaded p2Fras down-regulates agonist-stimulated inositol phosphate production by a mechanism involving protein kinase C (2005) (0)
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