Alan Heldman
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American interventional cardiologist
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Philosophy
Alan Heldman's Degrees
- Doctorate Medicine Johns Hopkins University
- PhD Biomedical Engineering Johns Hopkins University
Why Is Alan Heldman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Alan W. Heldman is an American interventional cardiologist. Heldman graduated from Harvard College, University of Alabama School of Medicine, and completed residency and fellowship training at Johns Hopkins University School of Medicine. He held positions on the faculty of Johns Hopkins from 1995 to 2007. In 2007, he became clinical chief of cardiology at the University of Miami's Leonard M. Miller School of Medicine.
Alan Heldman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. (2005) (1094)
- Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial. (2012) (1074)
- In Vivo Magnetic Resonance Imaging of Mesenchymal Stem Cells in Myocardial Infarction (2003) (739)
- Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation (2010) (694)
- Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity (2009) (596)
- Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. (1999) (495)
- Transendocardial mesenchymal stem cells and mononuclear bone marrow cells for ischemic cardiomyopathy: the TAC-HFT randomized trial. (2014) (476)
- Paclitaxel Stent Coating Inhibits Neointimal Hyperplasia at 4 Weeks in a Porcine Model of Coronary Restenosis (2001) (457)
- Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction (2013) (384)
- Intramyocardial Stem Cell Injection in Patients With Ischemic Cardiomyopathy: Functional Recovery and Reverse Remodeling (2011) (312)
- Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion, and Fibrotic Burden When Administered to Patients Undergoing Coronary Artery Bypass Grafting: The Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Sur (2014) (285)
- Inhibition of Restenosis With a Paclitaxel-Eluting, Polymer-Free Coronary Stent: The European evaLUation of pacliTaxel Eluting Stent (ELUTES) Trial (2004) (272)
- Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy: POSEIDON-DCM Trial. (2017) (260)
- Oral antibiotic treatment of right-sided staphylococcal endocarditis in injection drug users: prospective randomized comparison with parenteral therapy. (1996) (244)
- Focal modification of electrical conduction in the heart by viral gene transfer (2000) (203)
- Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapy. (2006) (163)
- Early improvement in cardiac tissue perfusion due to mesenchymal stem cells. (2008) (158)
- Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: A randomized, double-blind, placebo-controlled study of safety and effi (2011) (136)
- Dose Comparison Study of Allogeneic Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy (The TRIDENT Study) (2017) (132)
- Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy. (2015) (128)
- Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease (2015) (102)
- The transaortic approach for transcatheter aortic valve replacement: initial clinical experience in the United States. (2012) (95)
- Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2017) (94)
- Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally?: An Analysis From the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) Randomized Trial (2014) (90)
- Myocardial infarction and intramyocardial injection models in swine (2012) (86)
- Inhibitory G Protein Overexpression Provides Physiologically Relevant Heart Rate Control in Persistent Atrial Fibrillation (2004) (82)
- New-onset atrial fibrillation after aortic valve replacement: comparison of transfemoral, transapical, transaortic, and surgical approaches. (2013) (78)
- Acute effects of conjugated estrogens on coronary blood flow response to acetylcholine in men. (1997) (75)
- Durable Scar Size Reduction Due to Allogeneic Mesenchymal Stem Cell Therapy Regulates Whole‐Chamber Remodeling (2013) (72)
- Real-time projection MR angiography: feasibility study. (2000) (64)
- A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration. (2017) (62)
- Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty (2017) (60)
- Resuscitation and recovery from acute right ventricular failure using a percutaneous right ventricular assist device (2006) (54)
- Transesophageal magnetic resonance imaging (1999) (43)
- Adherence to appropriateness criteria for transthoracic echocardiography: comparisons between a regional department of Veterans Affairs health care system and academic practice and between physicians and mid-level providers. (2009) (41)
- Percutaneous retrograde left ventricular assist support for interventions in patients with aortic stenosis and left ventricular dysfunction (2012) (39)
- Single-vessel coronary artery stenosis: myocardial perfusion imaging with Gadomer-17 first-pass MR imaging in a swine model of comparison with gadopentetate dimeglumine. (2002) (39)
- Prognostic value of serial B-type natriuretic peptide measurement in transcatheter aortic valve replacement (from the PARTNER Trial). (2015) (38)
- Does Transendocardial Injection of Mesenchymal Stem Cells Improve Myocardial Function Locally or Globally?Novelty and Significance (2014) (38)
- MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS‐325 (2002) (37)
- Rationale and Design of the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis in Dilated Cardiomyopathy (The POSEIDON-DCM Study) (2014) (32)
- Elective or Emergency Use of Mechanical Circulatory Support Devices During Transcatheter Aortic Valve Replacement. (2016) (32)
- A minimally invasive method for creating coronary stenosis in a swine model for MRI and SPECT imaging. (2000) (31)
- Transseptal antegrade transcatheter aortic valve replacement for patients with no other access approach—A contemporary experience (2013) (29)
- Prospective evaluation of the relationship between platelet–leukocyte conjugate formation and recurrent myocardial ischemia in patients with acute coronary syndromes (2004) (26)
- Randomized trial of hormone therapy in women after coronary bypass surgery. Evidence of differential effect of hormone therapy on angiographic progression of disease in saphenous vein grafts and native coronary arteries. (2006) (26)
- Cell therapy for myocardial infarction: Special delivery. (2008) (23)
- Enhanced Effect of Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and Restore Cardiac Function after Myocardial Infarction (2012) (20)
- Endothelial cell Ca2+ increases upon tumor cell contact and modulates cell-cell adhesion. (1993) (19)
- Alternative access for transcatheter aortic valve replacement in older adults: A collaborative study from France and United States (2018) (19)
- Long‐term outcomes associated with the transaortic approach to transcatheter Aortic valve replacement (2015) (19)
- Management of paravalvular regurgitation after Edwards SAPIEN transcatheter aortic valve replacement: Management of paravalvular regurgitation after TAVR (2013) (18)
- Effects of Transendocardial Stem Cell Injection on Ventricular Proarrhythmia in Patients with Ischemic Cardiomyopathy: Results from the POSEIDON and TAC‐HFT Trials (2017) (17)
- EJ-Ras inhibits phospholipase C gamma 1 but not actin polymerization induced by platelet-derived growth factor-BB via phosphatidylinositol 3-kinase. (1996) (17)
- Genetic determinants of responsiveness to mesenchymal stem cell injections in non-ischemic dilated cardiomyopathy (2019) (17)
- Cell therapy for heart disease: where are we in 2011? (2011) (16)
- Clinical evaluation of a microsample coagulation analyzer, and comparison with existing techniques. (1996) (14)
- Myectomy or alcohol septal ablation surgery and percutaneous intervention go another round. (2007) (11)
- Microvascular obstruction after nonsurgical septal reduction for the treatment of hypertrophic cardiomyopathy. (2001) (10)
- Multidetector computerized tomography can guide and document alcohol septal ablation in hypertrophic obstructive cardiomyopathy. (2011) (9)
- The story of the lost needle: Foreign body embolization to the heart. (2015) (9)
- ST-Segment Elevation in an Unresponsive Patient (2003) (8)
- Transfemoral Aortic Valve Replacement in Failing Aortic Root Homografts (2014) (7)
- Effect on restenosis with a paclitaxel eluting stent: factors associated with inhibition in the elutes clinical study (2002) (7)
- Abstract 13079: Synergistic Effect of Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and Restore Cardiac Function (2011) (6)
- Cell signalling and motile activity. (1993) (6)
- DOES TRANSENDOCARDIAL INJECTION OF MESENCHYMAL STEM CELLS IMPROVE MYOCARDIAL FUNCTION LOCALLY, OR GLOBALLY: AN ANALYSIS FROM THE POSEIDON TRIAL (2013) (6)
- TCT-375 Optimizing Rotational Atherectomy in High-Risk Percutaneous Coronary Interventions. Insights from the PROTECT II study (2012) (5)
- Acute administration of estrogen improves coronary vasomotor response to acetylcholine in men (1996) (5)
- Impact of CMS coverage decision on access to transcatheter aortic valve replacement (2013) (5)
- Transient and persistent conduction abnormalities following transcatheter aortic valve replacement with the Edwards-Sapien prosthesis: a comparison between antegrade vs. retrograde approaches (2016) (5)
- TRANSCATHETER AORTIC VALVE REPLACEMENT VERSUS SURGICAL AORTIC VALVE REPLACEMENT IN A LOW TO INTERMEDIATE RISK POPULATION (2014) (5)
- Actin regulation and surface catalysis. (1994) (4)
- Distal occluder and rheolytic thrombectomy of a saphenous vein graft lesion with a large associated thrombus. (2002) (3)
- Use of stem cells for ischemic cardiomyopathy--reply. (2013) (3)
- Combined Retrograde/Antegrade Approach to Transcatheter Closure of an Aortic Paravalvular Leak. (2015) (3)
- Optimal characterization of myocardial perfusion with AngioMARK. (2002) (3)
- Abstract 12659: Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion, and Fibrotic Burden when Administered to Patients Undergoing Coronary Artery Bypass Grafting (2013) (3)
- Stenting small coronaries: Size does matter (1999) (3)
- Left subclavian artery stenosis with subclavian–subclavian bypass (2005) (2)
- Cerebral protection against left ventricular thrombus during transcatheter aortic valve replacement in a patient with critical aortic stenosis. (2013) (2)
- Direct stenting: Is the future near? (2000) (2)
- HEMODYNAMIC SUPPORT WITH IMPELLA 2.5 IN HIGH-RISK INTERVENTIONS FOR PATIENTS WITH AORTIC STENOSIS (2011) (2)
- Endothelial Cell Ca 2 + Increases upon Tumor Cell Contact and Modulates Cell-Cell Adhesion (2013) (2)
- PRELIMINARY RESULTS FROM THE TRANSENDOCARDIAL INJECTIONS OF AUTOLOGOUS WHOLE BONE MARROW AND MESENCHYMAL STEM CELLS IN ISCHEMIC HEART FAILURE (TAC-HFT) TRIAL (2011) (2)
- Emergent Percutaneous Biventricular Support during Transcatheter Aortic Valve Replacement. (2015) (2)
- Cardiac cell-based therapy: Methods of application and delivery systems (2013) (1)
- Stimuli of pepsinogen secretion from frog isolated peptic cells (1986) (1)
- Local delivery of paclitaxel as a stent coating (2005) (1)
- TCT-410 Arteriotomy Location Guided by Fluoroscopy Plus Real-time Ultrasound: In Defense of the Femoral Approach (2012) (1)
- Local delivery of paclitaxel as a stent coating: biology and clinical implications (2005) (1)
- Needling the heart (1999) (1)
- Treatment of saphenous vein graft thrombosis with distal protection, thrombectomy, and adenosine prior to reperfusion: a complete approach to preserving microvascular integrity. (2004) (1)
- Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion and Fibrotic Burden when Administered to Patients Undergoing Coronary Artery Bypass Grafting – The PROMETHEUS Trial (2014) (1)
- Abstract 15947: Merging Three-Dimensional Cardiac MRI with Electroanatomical Mapping to Guide Transendocardial Injections of Mesenchymal Stem Cells (2010) (1)
- TCT-189 The Use of Mechanical Circulatory Support Devices during TAVR: A Single Center Experience with Long Term Follow-up (2015) (1)
- Therapies Targeted at Preserving Microvascular Integrity and Preventing Reperfusion Injury (2009) (0)
- Stem Cell Therapy in Heart Failure (2017) (0)
- Abstract 12019: Durable Infarct Size Reduction Due to Allogeneic Mesenchymal Stem Cell Therapy Regulates Whole-Chamber Left Ventricular Remodeling (2012) (0)
- Images in Cardiovascular Medicine Multidetector Computerized Tomography Can Guide and Document Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy (2011) (0)
- Abstract 140: Effect of Transendocardial Autologous Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and Restore Cardiac Function in a Heart Failure Swine Model (2014) (0)
- TCT-417 Left Ventricular Assist Improves 90 Day Outcomes With Unprotected Left Main Coronary Intervention: Analysis From The Protect II Trial (2013) (0)
- Coronary perforation: Angioplasty out of control (2001) (0)
- TCT-876 Decreasing B – Type Natriuretic Peptide Predicts Survival After Transcatheter Aortic Valve Replacement (2012) (0)
- Abstract 20042: Comparison Between Alcohol Septal Ablation and Myomectomy for Hypertrophic Obstructive Cardiomyopahty: A Meta-Analysis (2014) (0)
- Drug Strategies for Angioplasty in Acute Myocardial Infarction (2002) (0)
- Pharmaceutical coposition of cardiac stem cells and mesenchymal stem cells (2014) (0)
- Good vibrations (1999) (0)
- Cell Therapy in Acute Myocardial Infarction (2009) (0)
- Yes reflow. (1999) (0)
- ON–LABEL AND OFF–LABEL USE OF TRANSCATHETER HEART VALVES IN INOPERABLE AORTIC STENOSIS PATIENTS: EARLY CLINICAL EXPERIENCE IN THE UNITED STATES (2013) (0)
- Transesophageal Magnetic Resonance Imaging of Thoracic Aorta Using an Esophageal Loopless Antenna (1998) (0)
- Cell Tracking Following the Intramyocardial Injection of Mesenchymal Cells after Myocardial Infarction (2006) (0)
- TRANSSEPTAL ANTEGRADE TRANSCATHETER AORTIC VALVE REPLACEMENT FOR NO–ACCESS OPTION PATIENTS: A CONTEMPORARY EXPERIENCE (2013) (0)
- Abstract 3545: Cytoprotective Actions of Mesenchymal Stem Cell Therapy After Acute Myocardial Infarction (2009) (0)
- Abstract 734: Cell Tracking Following the Intramyocardial Injection of MSCs After Myocardial Infarction (2006) (0)
- INTRAMYOCARDIAL STEM CELL INJECTION CAN REVERSE THE LEFT VENTRICULAR SPHERICAL REMODELING OF ISCHEMIC CARDIOMYOPATHY: TURNING SOCCER BALLS INTO (AMERICAN) FOOTBALLS (2012) (0)
- Risk Factors And Clinical Signi fi cance Of Intra-Procedural Haemodynamic Instability In Patients Undergoing Transcatheter Aortic Valve Implantation (2014) (0)
- AR INDEX POST IMPLANT OF TWO DIFFERENT TRANSCATHETER AORTIC VALVES (2013) (0)
- NON-TRANSFEMORAL TRANSCATHETER AORTIC VALVE IMPLANTATION: RESULTS FROM THE FRENCH-AMERICAN REGISTRY (2016) (0)
- Side balloon stenting of the left main bifurcation: a three-year angiographic follow-up. (2009) (0)
- FATIGUE FAILURE AND REPLACEMENT OF A MAINSPRING BY LES P POOK (2009) (0)
- TCT-865 Rotational Aortography With CT Reconstruction Can Guide Transcatheter Aortic Valve Replacement And Predict Prosthetic Regurgitation (2012) (0)
- Abstract 20389: Transendocardial Stem Cell Injection Site Tissue Viability Predicts Scar Size Reduction in Myocardial Segmental Analysis in a Swine Model of Ischemic Cardiomyopathy (2014) (0)
- Abstract 12085: Arrhythmogenic Effects of Cardiac Mesenchymal Stem Cell Implantation: Results From the POSEIDON and TAC-HFT Trials (2014) (0)
- Allogeneic Mesenchymal Stem Cells Improve Vessel Maturation and Reduce Apoptosis in Regions of Ischemically Damaged Myocardium (2006) (0)
- Abstract 18288: Prompt Revascularizations vs. Intensive Medical Therapy for Chronic Total Occlusions of Coronary Arteries: Results from BARI-2D Trial (2014) (0)
- Yes reflow (1999) (0)
- Images in cardiovascular medicine. ST-segment elevation in an unresponsive patient. (2003) (0)
- Real-time Projection MR Angiography : Feasibility (2000) (0)
- Abstract 2242: Infarct Size Reduction Correlates with Increaed Contractility after Treatment with Allogeneic Mesenchymal Stem Cells (2008) (0)
- PREDICTORS OF NET ADVERSE CLINICAL EVENTS POST BALLOON AORTIC VALVULOPLASTY: RESULTS FROM THE BRAVO (EFFECT OF BIVALIRUDIN ON AORTIC VALVE INTERVENTION OUTCOMES) STUDY (2012) (0)
- Abstract 246: Transendocardial Injections of Allogeneic Mesenchymal Stem Cells Demonstrate Reversal of Left Ventricular Remodeling to Baseline (2012) (0)
- NOTCH1 IS ASSOCIATED WITH THE DEVELOPMENT OF TRI-LEAFLET CALCIFIC AORTIC STENOSIS (2014) (0)
- TCT-875 Frailty is a Major Determinant of Length of Stay After Transcatheter Aortic Valve Replacement (2012) (0)
- Persistent native aortic valve function after transcatheter aortic valve replacement. (2013) (0)
- TCT-778 A Comparison of the Complications and Mortality between the Transapical and Transfemoral Accesses for Transcatheter Aortic Valve Replacement with Edwards SAPIEN valve: PARTNER Trial vs Worldwide Studies and Registries (2014) (0)
- IMPACT OF VASCULAR CLOSURE WITH THE PRE-CLOSURE TECHNIQUE ON ADVERSE EVENTS IN PATIENTS UNDERGOING TRANSFEMORAL BALLOON AORTIC VALVULOPLASTY: RESULTS FROM A 2-CENTER registry (2012) (0)
- PS168. Novel Aorto-Ilio-Femoral Assessment (AIFA) for the Evaluation of Access Vessels Based on Unenhanced Computer Tomography (CT) (2012) (0)
- Abstract 15481: LV Systolic Dysfunction is Improved by TAVR: Insights From the French-American Registry (2015) (0)
- Abstract 9609: Impact of Mesenchymal Stem Cell Left Ventricular Implantation on Heart Rate Variability: Results From the POSEIDON Trial (2013) (0)
- ONE YEAR OUTCOME AFTER PERCUTANEOUS CLOSURE OF PARAVALVULAR LEAKS OF EDWARDS-SAPIEN TRANSCATHETER AORTIC VALVE (2014) (0)
- Abstract 15440: The Incidence and Outcomes of Acute Kidney Injury After TAVR (2015) (0)
- PATENCY Pilot study: a negative trial, in context (2005) (0)
- TCT-658 Left Bundle Branch Block and Need for Permanent Pacemaker Post TAVR (2015) (0)
- TCT-785 Comparison of 30-day Major Vascular Complications between Transfemoral and Transapical Accesses in Transcatheter Aortic Valve Replacement: an Updated Meta-Analysis using Standardized Definitions (2014) (0)
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