Alan R. Battersby
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British chemist
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Why Is Alan R. Battersby Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Alan Rushton Battersby was an English organic chemist best known for his work to define the chemical intermediates in the biosynthetic pathway to vitamin B12 and the reaction mechanisms of the enzymes involved. His research group was also notable for its synthesis of radiolabelled precursors to study alkaloid biosynthesis and the stereochemistry of enzymic reactions. He won numerous awards including the Royal Medal in 1984 and the Copley Medal in 2000. He was knighted in the 1992 New Year Honours. Battersby died in February 2018 at the age of 92.
Alan R. Battersby's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tetrapyrroles: the pigments of life. (2000) (290)
- Oxidative coupling of phenols (1967) (265)
- Biosynthesis of the pigments of life: formation of the macrocycle (1980) (178)
- How nature builds the pigments of life: the conquest of vitamin B12. (1994) (147)
- Vitamin B12: How the Problem of Its Biosynthesis Was Solved (1995) (124)
- Enzymes in organic synthesis. (1985) (97)
- THE MOLECULAR WEIGHT DETERMINATION OF POLYPEPTIDES (1951) (77)
- Biosynthesis of the pigments of life: mechanistic studies on the conversion of porphobilinogen to uroporphyrinogen III (1990) (75)
- Purification and properties of uroporphyrinogen III synthase (co-synthetase) from Euglena gracilis. (1985) (64)
- Studies on specific chemical fission of peptide links. Part I. The rearrangement of aspartyl and glutamyl peptides (1955) (62)
- Biosynthesis of the natural porphyrins: proof that hydroxymethylbilane synthase (porphobilinogen deaminase) uses a novel binding group in its catalytic action (1987) (62)
- Studies of enzyme-mediated reactions. Part 12. Stereochemical course of the decarboxylation of (2S)-tyrosine to tyramine by microbial, mammalian, and plant systems. (1980) (61)
- Biosynthesis of the indole and colchicum alkaloids (1967) (60)
- Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding. (1991) (59)
- Proof by synthesis that unrearranged hydroxymethylbilane is the product from deaminase and the substrate for cosynthetase in the biosynthesis of uro'gen-III (1979) (59)
- 444. Investigations on the biosynthesis of morphine alkaloids (1965) (58)
- 603. Alkaloid biosynthesis. Part VIII. Use of optically active precursors for investigation on the biosynthesis of morphine alkaloids (1965) (55)
- Order of assembly of the four pyrrole rings during biosynthesis of the natural porphyrins (1979) (52)
- Cyclopentanoid terpene derivatives (1969) (49)
- 697. Alkaloid biosynthesis. Part IV. 1-Benzylisoquinolines as precursors of thebaine, codeine, and morphine (1964) (48)
- Origin of the pigments of life: the type-III problem in porphyrin biosynthesis (1979) (47)
- Biosynthesis of vitamin B12: structure of precorrin-6x octamethyl ester. (1990) (45)
- Biosynthesis of the natural porphyrins: experiments on the ring-closure steps and with the hydroxy-analogue of porphobilinogen (1979) (44)
- Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound through the sulphur atom of a cysteine residue. (1988) (44)
- Studies of enzyme-mediated reactions. Part 13. Stereochemical course of the formation of histamine by decarboxylation of (2S)-histidine with enzymes from Clostridium welchii and Lactobacillus 30a. (1980) (43)
- The Chemistry of Tyrocidine. I. Isolation and Characterization of a Single Peptide (1952) (42)
- Biosynthesis of porphyries and related macrocycles. Part 18. Proof by spectroscopy and synthesis that unrearranged hydroxymethylbilane is the product from deaminase and the substrate for cosynthetase in the biosynthesis of uroporphyrinogen-III (1982) (42)
- Purification of porphobilinogen deaminase from Euglena gracilis and studies of its kinetics. (1981) (41)
- Evidence that the pyrromethane cofactor of hydroxymethylbilane synthase (porphobilinogen deaminase) is bound to the protein through the sulphur atom of cysteine-242. (1988) (38)
- Stereochemical course of the elimination catalysed by L-phenylalanine ammonia-lyase and the configuration of 2-benzamidocinnamic azlactone (1971) (37)
- Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle. (1981) (37)
- Alkaloid biosynthesis. Part XV. Partial synthesis and isolation of vincoside and isovincoside: biosynthesis of the three major classes of indole alkaloids from vincoside (1969) (36)
- Synthetic applications of 1,2-dihydroisoquinolines : Synthesis of (±)-coreximine (1961) (36)
- Studies of enzyme-mediated reactions. I. Syntheses of deuterium- or tritium-labelled (3S)-and (3R)-phenylalanines: stereochemical course of the elimination catalysed by L-phenylalanine ammonia-lyase. (1972) (35)
- Biosynthesis of porphyrins and related, macrocycles. Part 28. Development of a pulse labelling method to determine the C-methylation sequence for vitamin B12 (1987) (35)
- The Chemistry of Tyrocidine. II. Molecular Weight Studies (1952) (33)
- SYNTHESIS AND PROPERTIES OF RING-DEACTIVATED DEUTERATED (HYDROXYMETHYL)PYRROLES (1998) (33)
- Biosynthesis. Part XXII. The origin of chelidonine and of other alkaloids derived from the tetrahydroprotoberberine skeleton (1975) (33)
- Biosynthesis of vitamin B12 (1986) (33)
- The sequence of hemC, hemD and two additional E. coli genes. (1988) (32)
- Alkaloid biosynthesis. Part XIV. Secologanin: its conversion into ipecoside and its role as biological precursor of the indole alkaloids (1969) (32)
- Total synthesis of (±)-bonellin dimethyl ester (1983) (32)
- Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli. (1993) (31)
- Synthetic studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins: inhibition of cosynthetase (1986) (31)
- Biosynthesis of porphyrins and related macrocycles. Part 21. The interaction of deaminase and its product (hydroxymethylbilane) and the relationship between deaminase and cosynthetase (1983) (30)
- Biosynthesis of type-III porphyrins: proof of intact ezymic conversion of the head-to-tail bilane into uro'gen-III by intramolecular rearrangement (1978) (30)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 7. Synthesis of (±)-bonellin dimethyl ester (1988) (30)
- Biosynthesis of porphyrins and related macrocycles. Part 20. Purification of deaminase and studies on its mode of action (1983) (29)
- Biosynthesis of porphyrins and related macrocycles (1986) (29)
- Biosynthesis of vitamin B12: Structural studies on the corriphryins from and the link with sirohydrochlorin (1977) (29)
- Uroporphyrinogen III synthase: Studies on its mechanism of action, molecular biology and biochemistry (1991) (29)
- Synthesis of a doubly-bridged oxygen-carrier which shows reduced affinity for carbon monoxide (1980) (28)
- 246. Chemical correlation of the absolute configurations of salsolidine, salsoline, and calycotomine with the amino-acids (1960) (28)
- Alkaloids of calabash-curare and Strychnos species (1960) (28)
- Biosynthesis of porphyries and related macrocycles. Part 17. Chemical and enzymic transformation of isomeric aminomethylbilanes into uroporphyrinogens: proof that unrearranged bilane is the preferred enzymic substrate and detection of a transient intermediate (1982) (28)
- The structures and chemistrty of isobacteriochlorins from (1977) (27)
- Biosynthesis of porphyrins and corrins. (1976) (27)
- Biosynthesis of vitamin B12: isolation of 15,23-dihydrosirohydrochlorin, a biosynthetic intermediate: structural studies and incorporation experiments (1982) (26)
- BIOSYNTHESIS IN THE AMARYLLIDACEAE. TYROSINE AND NORBELLADINE AS PRECURSORS OF HAEMANTHAMINE (1961) (26)
- Alkaloid biosynthesis. Part XVIII. Biosynthesis of colchicine from the 1-phenethylisoquinoline system (1972) (25)
- A Synthetic Approach to the Isobacteriochlorin Macrocycle (1979) (25)
- Stereochemistry of biosynthesis of the vinyl groups of protoporphyrin-IX: a short synthesis of porphobilinogen (1975) (25)
- Biosynthesis of porphyrins and related macrocycles. Part 29. Synthesis and chemistry of 2,2-disubstituted 2H-pyrroles (pyrrolenines) (1987) (25)
- Alkaloid biosynthesis. Part XII. The biosynthesis of narcotine (1968) (24)
- Biosynthesis of type-III porphyrins: nature of the rearrangement process (1973) (24)
- The intermediacy of geissoschizine in indole alkaloid biosynthesis: rearrangement to the Strychnos skeleton (1969) (24)
- Biosynthesis of vitamin B12: analysis of the 1H and 13C n.m.r. spectra of heptamethyl dicyanocobyrinate (cobester) (1982) (24)
- Biosynthesis of porphyrins and related macrocycles. Part VIII. Enzymic decarboxylation of uroporphyrinogen-II: Structure of an intermediate, phyriaporphyrinogen-III, and synthesis of the corresponding porphyrin and of two isomeric porphyrins. (1976) (23)
- Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfers. (1977) (23)
- Biosynthesis of porphyrins and related macrocycles. Part 40. Synthesis of a spiro-lactam related to the proposed spiro-intermediate for porphyrin biosynthesis: inhibition of cosynthetase (1993) (22)
- Biosynthesis of the pigments of life. (1988) (22)
- Experiments on the early steps of morphine biosynthesis (1975) (22)
- Biosynthesis of Natural Porphyrins: Studies with Isomeric Hydroxymethylbilanes on the Specificity and Action of Cosynthetase†‡ (1981) (21)
- Biosynthesis of loganin and the indole alkaloids from hydroxygeraniol–hydroxynerol (1970) (21)
- Modification of hydroxymethylbilane synthase (porphobilinogen deaminase) by pyridoxal 5'-phosphate. Demonstration of an essential lysine residue. (1984) (21)
- Purification, N-terminal amino acid sequence and properties of hydroxymethylbilane synthase (porphobilinogen deaminase) from Escherichia coli. (1986) (21)
- Biosynthesis of porphyrins and related macrocycles. I. Synthesis of 14C-labelled pyrromethanes. (1973) (21)
- 399. Optical rotatory dispersion. Part XIV. Bisbenzyltetra-hydroisoquinoline alkaloids (1965) (21)
- 691. Alkaloid biosynthesis. Part I. The biosynthesis of papaverine (1962) (21)
- Pavine. Part I. The structure and chemistry of pavine (1955) (21)
- Biosynthesis of porphyrins and related macrocycles. Part III. Rational syntheses of [β-13C]-, [γ-13C]-, and [δ-13C]-protoporphyrin-IX: assignment of the 13C nuclear magnetic resonance signals from the meso-carbon atoms of protoporphyrin-IX dimethyl ester (1973) (20)
- 4. Alkaloids of Kopsia species. Part I. Kopsine, fruticosamine, and fruticosine (1963) (20)
- Biosynthesis of vitamin B12: proof of A-B structure for sirohydrochlorin by its specific incorporation into cobyrinic acid (1978) (20)
- THE ALKALOIDS OF PAPAVERACEOUS PLANTS: LIV. THE STRUCTURE OF ESCHSCHOLTZINE (1965) (20)
- Studies of enzyme-mediated reactions. Part VII. Stereospecific syntheses of tritium-labelled (2R)- and (2S)-dopamines: stereochemical course of hydroxylation of dopamine by dopamine beta-hydroxylase (E.C. 1.14.17.1). (1976) (20)
- 149. Ipecacuanha alkaloids. Part V. Stereospecific synthesis of (+)-O-methylpsychotrine and (–)-emetine (1960) (20)
- The Reaction of N-Magnesium Derivatives of Pyrroles with N-Mesylchloromethylpyrroles: A Synthesis of Dipyrrylmethanes (1998) (19)
- Biosynthesis of porphyrins and related macrocycles. Part VI. Nature of the rearrangement process leading to the natural type III porphyrins. (1976) (19)
- Synthetic sudies related to myoglobin: syntheses of bridged porphyrin systems (1976) (19)
- Biosynthesis of the Cinchona alkaloids: late stages of the pathway (1971) (18)
- 692. Alkaloid biosynthesis. Part II. The biosynthesis of morphine (1962) (18)
- Biosynthesis of porphyrins and related macrocycles. Part V. Structural integrity of the type III porphyrinogen macrocycle in an active biological system; studies on the aromatisation of protoporphyrinogen-IX. (1976) (18)
- Alkaloid biosynthesis. Part XIII. The structure, stereochemistry, and biosynthesis of loganin (1969) (18)
- Biosynthesis. Part XXI. Investigations on the biosynthesis of stylopine in Chelidonium majus (1975) (18)
- Biosynthesis of vitamin B12: pulse labelling experiments to locate the fourth methylation site (1982) (17)
- The spiro intermediate proposed for biosynthesis of the natural porphyrins: synthesis and properties of its macrocycle (1985) (17)
- Mechanism of biosynthesis of the vinyl groups of protoporphyrin-IX (1972) (17)
- Biosynthesis of porphyrins and related macrocycles. Part 30. Synthesis of the macrocycle of the spiro system proposed as an intermediate generated by cosynthetase (1988) (17)
- 13C-N.M.R. Studies on the pyrromethane cofactor of hydroxymethylbilane synthase (1988) (17)
- Studies of enzyme-mediated reactions. Part 9. Stereochemistry of oxidative ring cleavage adjacent to nitrogen during the biosynthesis of chelidonine (1979) (17)
- Biosynthesis of vitamin B12: structure of the trimethylisobacteriochlorin from Propionibacterium shermanii (1979) (17)
- Biosynthesis of porphyrins and related macrocycles. Part 42. Pulse labelling experiments concerning the timing of cobalt insertion during vitamin B12 biosynthesis (1994) (16)
- Applications of tritium labeling for the exploration of biochemical mechanisms (1972) (16)
- Biosynthesis of the apparently “directly coupled” aporphine alkaloids (1971) (16)
- Determination of the structure of seleno-methionine-labelled hydroxymethylbilane synthase in its active form by multi-wavelength anomalous dispersion. (1999) (16)
- Studies of enzyme-mediated reactions. Part V. Synthesis of (13S)- and (13R)-[13-3H1]scoulerine from stereospecifically labelled (R)- and (S)-[α3H1]benzyl alcohols; stereochemistry of enzymic reactions at saturated benzylic carbon (1975) (16)
- Nature's pathways to the pigments of life. (1987) (16)
- Expression, purification and characterisation of the product from the Bacillus subtilis hemD gene, uroporphyrinogen III synthase. (1995) (16)
- 499. The synthesis of emetine and related compounds. Part II. The synthesis of (±)-rubremetinium bromide (1953) (16)
- Stereospecificity of some enzymic reactions (1974) (16)
- Model studies on the active site of cytochrome P-450 : an FeII–porphyrin carrying a strapped thiolate ligand (1982) (16)
- Linear tetrapyrrolic intermediates for biosynthesis of the natural porphyrins (1983) (16)
- 1-phenethylisoquinoline alkaloids. II. The structures of alkaloids from Colchicum cornigerum (Sweinf.) Tackh. et Drar. (1971) (15)
- 316. Alkaloid biosynthesis. Part III. Amaryllidaceae alkaloids: the biosynthesis of lycorine and its relatives (1964) (15)
- 819. Alkaloid biosynthesis. Part VI. The biosynthesis of colchicine (1964) (15)
- Models for haemoglobin–myoglobin: studies with loosely and tightly strapped imidazole ligands (1983) (15)
- Biosynthesis of the Chinchona alkaloids: middle stages of the pathway (1971) (15)
- Biosynthesis of vitamin B12: structure of the ester of a new biosynthetic intermediate, precorrin-6y (1992) (15)
- 368. Alkaloids of calabash-curare and Strychnos species. Part II. Isolation of new alkaloids (1960) (15)
- Biosynthesis of vitamin B12: structural studies on precorrin-8x, an octamethylated intermediate and the structure of its stable tautomer (1992) (15)
- Studies of enzyme-mediated reactions. Part VI. Stereochemical course of the dehydrogenation of stereospecifically labelled benzylamines by the amine oxidase from pea seedlings (E.C. 1.4.3.6.). (1976) (15)
- Structure of a heptacarboxylic porphyrin enzymically derived from porphobilinogen (1974) (15)
- Rate study on the incorporation of tyrosine into morphine, codeine and thebaine (1960) (15)
- Biosynthesis. Part 30.1 Colchicine: studies on the ring expansion step focusing on the fate of the hydrogens at C-4 of autumnaline (1998) (15)
- Studies of enzyme-mediated reactions. II. Stereochemistry of the elimination of ammonia from L-tyrosine catalysed by the enzyme from maize. (1972) (15)
- Preparation and spectroscopic properties of CoIII-isobacteriochlorins: relationship to the cobalt-containing proteins from Desulphovibrio gigas and D. desulphuricans (1982) (15)
- 405. Pavine. Part II. The structure of isopavine (1958) (14)
- How Nature builds the pigments of life (1993) (14)
- Biosynthesis in the Amaryllidaceae. Incorporation of 3-C14-Tyrosine and Phenylalanine inNerine BowdeniiW. Wats. (1962) (14)
- Investigation of putative active-site lysine residues in hydroxymethylbilane synthase. Preparation and characterization of mutants in which (a) Lys-55, (b) Lys-59 and (c) both Lys-55 and Lys-59 have been replaced by glutamine. (1990) (14)
- Biosynthesis. XIX. Concerning the biosynthesis of (-)-camphor and (-)-borneol in Salvia officinalis. (1972) (14)
- Alkaloid biosynthesis. Part XVI. Colchicine: origin of the tropolone ring and studies with the C6–C3–C6–C1 system (1972) (14)
- Loganin as precursor of the indole alkaloids (1968) (14)
- Partial synthesis and isolation of vincoside and isovincoside: biosynthesis of the three major classes of indole alkaloids from the β-carboline system (1968) (14)
- Novel Methods for Demetalating Tetrapyrrolic Metallo‐Macrocycles (1983) (14)
- The molecules of nature : by James B. Hendrickson, Benjamin, New York, 1965, 192 pp., $7.00 (for the U.S.A.) or $7.70; paperback $3.95 (1967) (14)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 9. Synthesis of 20-methyl and 20-cyano isobacteriochlorins (1989) (14)
- Biosynthesis of vitamin B12: mechanistic studies on the transfer of a methyl group from C-11 to C-12 and incorporation of 18O (1994) (14)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 1. Syntheses of C-methylated chlorins based on 1-pyrrolines (3,4-dihydropyrroles) (1985) (14)
- Biosynthesis of porphyrins and related macrocycles. Part II. Synthesis of δ-amino[5-13C]laevulinic acid and [11-13C] porphobilinogen: incorporation of the latter into protoporphyrin-IX (1973) (14)
- Preparation and isolation of deoxyloganin: its role as precursor of loganin and the indole alkaloids (1970) (14)
- Stereochemistry of formation of the hydroxymethyl group of hydroxymethylbilane, the precursor of uro'gen-III (1987) (14)
- Further studies on the synthesis and biosynthesis of isothebaine (1969) (14)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 6. Synthesis of chlorins by a photochemical approach (1988) (14)
- Biosynthesis of the Pigments of Life a (1986) (14)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 5. Synthesis of (RS)-ring-B imide (1987) (14)
- 1365. Alkaloid biosynthesis. Part IX. The Ipecacuanha alkaloids (1965) (14)
- Stereochemistry of formation of methyl and ethyl groups in bacteriochlorophyll a (1981) (14)
- Biosynthesis of vitamin B12: synthesis of (±)-[5-13C]faktor-1 ester: determination of the oxidation state of precorrin-1 (1989) (13)
- Biosynthesis of vitamin B12: Isobacteriochlorins, the link between corrins and sulphite reductases (1978) (13)
- 347. Ipecacuanha alkaloids. Part II. The structure of protoemetine and a partial synthesis of (–)-emetine (1959) (13)
- Biosynthesis of the natural (type-III) porphyrins: proof that rearrangement occurs after head-to-tail bilane formation (1977) (13)
- Structure and synthesis of homoaporphines: a new group of 1-phenethylisoquinoline alkaloids (1967) (13)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 2. Syntheses of C-methylated chlorins via lactams (1985) (13)
- Studies of enzyme-mediated reactions. Part 10. Stereochemical course of the dehydrogenation of stereospecifically labelled 1-amino-heptanes by the amine oxidase from rat liver mitochondria (E.C. 1.4.3.4). (1979) (13)
- Biosynthesis of vitamin B12: the site of reduction of precorrin-6x (1991) (13)
- Studies of enzyme-mediated reactions. Part IV. Complementary syntheses of stereospecifically labelled (R)- and (S)-[alpha-3H1]benzyl alcohol derivatives by use of liver alcohol dehydrogenase. (1975) (13)
- Further studies on rearrangements during biosynthesis of indole alkaloids (1971) (13)
- Biosynthesis in the Amaryllidaceae. The Incorporation of 3-C14-Tyrosine in Sprekelia Formosissima (1962) (13)
- 152. Alkaloids of calabash curare and strychnos species. Part I. Chemistry and structure of hemitoxiferine-I and toxiferine-I, including the preparation of toxiferine-I (1960) (13)
- The mechanism of indole alkaloid biosynthesis (1968) (13)
- Evidence from synthesis and isolation concerning the rearrangement process in indole alkaloid biosynthesis (1970) (13)
- Biosynthesis of pellotine. (1968) (13)
- Haem d1: Stereoselective synthesis of the macrocycle to establish its absolute configuration as 2R,7R (1997) (13)
- Preparation of secologanin: its conversion into ipecoside and its role in indole alkaloid biosynthesis (1968) (12)
- Biosynthesis of vitamin B12: order of the later C-methylation steps (1985) (12)
- Biosynthesis of vitamin B12: experiments on loss of C-20 from the precursor macrocycle (1979) (12)
- Stereochemistry of oxidation of benzylamine by the amine oxidase from beef plasma (1979) (12)
- Biosynthesis of vitamin B12: when is the 12β-methyl group of the vitamin generated by acetate decarboxylation? (1988) (12)
- Synthetic routes to C-methylated chlorins (1981) (12)
- Synthetic studies relevant to biosynthetic research on vitamin B. Part 3. An approach to isobacteriochlorins via nitrones (1984) (12)
- Biosynthesis of porphyrins and related macrocycles. Part 41. Fate of oxygen atoms as precorrin-2 carrying eight labelled carboxyl groups (13C18O2H) is enzymatically converted into cobyrinic acid (1993) (12)
- Synthesis of the isobacteriochlorin macrocycle: a photochemical approach (1981) (12)
- Alkaloid biosynthesis. Part XVII. The structure and chemistry of androcymbine (1972) (12)
- Synthetic studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins: the stereochemical probe (1991) (12)
- Biosynthesis of natural porphyrins: enzymic experiments on isomeric bilanes (1978) (12)
- 839. Syntheses along biosynthetic pathways. Part I. Synthesis of (+)-isothebaine (1965) (12)
- Stereochemical studies on porphyrin a: assignment of the absolute configuration of a model porphyrin by degradation (1986) (11)
- 407. Studies on specific chemical fission of peptide links. Part II. The preparation and hydrolysis of 1-acylpyrrolid-2-ones derived from α-glutamyl peptides (1956) (11)
- Structure, stereochemistry, and biosynthesis of loganin (1968) (11)
- INVESTIGATIONS ON THE BIOSYNTHESIS OF MORPHINE ALKALOIDS. (1965) (11)
- The basic glucosides related to the biosynthesis of indole and ipecac alkaloids (1978) (11)
- The biosynthesis of narciclasine (1971) (11)
- Biosynthesis. Part 27.1,2 Colchicine: studies of the phenolic oxidative coupling and ring-expansion processes based on incorporation of multiply labelled 1-phenethylisoquinolines (1998) (11)
- Evidence that pyridoxal phosphate modification of lysine residues (Lys-55 and Lys-59) causes inactivation of hydroxymethylbilane synthase (porphobilinogen deaminase). (1989) (11)
- X-Ray determination of the structure of OO-dimethylipecoside (1971) (11)
- Biosynthesis of porphyrins and related macrocycles. Part 45. Determination by a novel X-ray method of the absolute configuration of the spiro lactam which inhibits uroporphyrinogen III synthase (cosynthetase) (1996) (11)
- Biosynthesis of porphyrins and related macrocycles. Part 34. Synthesis and properties of S-pyrrolylmethylcysteinyl and ε-N-pyrrolylmethyllysyl peptides (1989) (11)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 8. Synthesis of (±)-Faktor-I octamethyl ester (1988) (11)
- Biosynthesis of vitamin B12: evidence from double-labelling studies (13CD3) for intact incorporation of seven methyl groups (1976) (11)
- Synthesis of the chlorin macrocycle by a photochemical approach (1984) (11)
- Haem d1: development of a new coupling procedureleading to the synthesis of isobacteriochlorins1 (1997) (11)
- ALKALOID BIOSYNTHESIS. 8. USE OF OPTICALLY ACTIVE PRECURSORS FOR INVESTIGATIONS ON THE BIOSYNTHESIS OF MORPHINE ALKALOIDS. (1965) (11)
- 849. Alkaloids of calabash-curare and Strychnos species. Part III. Structure and absolute stereochemistry of macusine-A, macusine-B, and macusine-C (1964) (11)
- Synthetic routes to singly and doubly bridged porphyrins (1978) (11)
- Biosynthesis of vitamin B12: derivation of cobyrinic acid from uroporphyrinogen-III (1975) (11)
- Biosynthesis of vitamin B12: the macrocycle and studies on the geminal methyl groups of ring c (1973) (10)
- Haem d1: stereoselective synthesis of the reducedform of its parent macrocycle using the original coupling strategy (1997) (10)
- Alkaloids of Kopsia species. II. The constitution of fruticosine and fruticosamine. (1967) (10)
- Studies of porphyrin biosynthesis by 13C-nuclear magnetic resonance; synthesis of [13C]porphobilinogen and its incorporation into protoporphyrin-IX (1972) (10)
- Role of loganin in the biosynthesis of indole alkaloids (1966) (10)
- Syntheses relevant to vitamin B12 biosynthesis: synthesis of sirohydrochlorin and of its octamethyl ester (1985) (10)
- 763. Ipecacuanha alkaloids. Part VII. The structure of emetamine: stereospecific synthesis of (±)-emetamine and indole analogues of the ipecacuanha alkaloids (1961) (10)
- Synthesis of (11S)- and (11R)-[11-2H1]porphobilinogen; stereochemical studies on hydroxymethylbilane synthase (PBG deaminase) (1985) (10)
- Biosynthesis of the Ipecac alkaloids and of ipecoside (1971) (10)
- Biosynthesis of colchicine: incorporation of a 13c-labelled precursor in a higher plant (1974) (10)
- Biosynthesis of colchicine: ring expansion and later stages. Structure of speciosine (1967) (10)
- Biosynthesis of porphyrins and related macrocycles. Part 9. Biosynthesis of the corrin macrocycle of vitamin B12 including the sterochemistry of C-methylation in ring. (1977) (10)
- Configuration of reticuline in the opium poppy. (1965) (10)
- Biosynthesis—II. Terpenoid indole alkaloids (1971) (10)
- Homoaporphine systems and related dienones: isolation, structure, and synthesis (1967) (10)
- Synthesis of (+)- and (–)-scoulerine and of (+)- and (–)-coreximine (1966) (9)
- Biosynthesis. Part 28.1,2 Colchicine: definition of intermediates between O-methylandrocymbine and colchicine and studies on speciosine (1998) (9)
- Biosynthesis of the indole alkaloids from a monoterpene (1966) (9)
- Biosynthesis of porphyrins and related macrocycles. Part 16. Proof that the single intramolecular rearrangement leading to natural porphyrins (type-III) occurs at the tetrapyrrole level (1981) (9)
- Biosynthesis of quinine from loganin (1970) (9)
- Biosynthesis of vitamin B12: stereochemistry of transfer of a hydride equivalent from NADPH by precorrin-6x reductase (1992) (9)
- Biosynthesis of porphyrins and related macrocycles. Part 50.1 Synthesis of the N-formyl-dihydro analogue of the spiro-intermediate and its interaction with uroporphyrinogen III synthase (1998) (9)
- The biosynthesis of hasubanonine and protostephanine (1974) (9)
- Biosynthesis of the indole alkaloids (1966) (9)
- Biosynthesis of porphyrins and related macrocycles. Part 25. Synthesis of analogues of coproporphyrinogen-III and studies of their interaction with coproporphyrinogen-III oxidase from Euglena gracilis (1985) (9)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 4. Development of the photochemical route to isobacteriochlorins (1987) (9)
- Synthesis relevant to vitamin B12 biosynthesis: synthesis of (±)Faktor-I octamethyl ester (1985) (9)
- Intermediates in porphyrin biosynthesis: studies with 14C- and 13C-labelled pyrromethanes (1973) (9)
- Biosynthesis of porphyrins and related macrocycles. Part 35. Discovery of a novel dipyrrolic cofactor essential for the catalytic action of hydroxymethylbilane synthase (porphobilinogen deaminase) (1990) (9)
- Biosynthesis of vitamin B12: stereochemistry of the decarboxylation step which generates the 12-si-methyl group (1983) (9)
- 707. Ipecacuanha alkaloids. Part IV. The relative and absolute stereochemistry of the benzoquinolizidine system of emetine (1959) (9)
- Alkaloid biosynthesis. X. Terminal steps in the biosynthesis of the morphine alkaloids. (1967) (9)
- Synthetic and biosynthetic studies on vitamin B12. (1988) (8)
- Biosynthesis of porphyrins and related macrocycles. Part 13. Structure of the protoporphyrin isomer derived from coproporphyrinogen IV by the action of beef-liver coproporphyrinogenase: synthesis of protoporphyrin XIII. (1980) (8)
- Biosynthesis. Part 26. Synthetic studies on structural modification of late biosynthetic precursors for colchicine (1983) (8)
- 192. The absolute stereochemistry of narcotine and narcotoline (1965) (8)
- Biosynthesis of chelidonine and stylopine (1965) (8)
- Biosynthesis of the ipecac alkaloids and of ipecoside, a cleaved cyclopentane monoterpene (1968) (8)
- CONCERNING THE BIOSYNTHESIS OF NARCOTINE. (1965) (8)
- Seco-cyclopentane glucosides from Menyanthes trifoliata: foliamenthin, dihydrofoliamenthin, and menthiafolin (1968) (8)
- Synthesis of 20-methyl and 20-cyano isobacteriochlorins: the Witting–photochemical approach (1984) (8)
- Mechanistic study of the enzymic incorporation of unrearranged AP·AP pyrromethane into uro'gen-III (1977) (8)
- X-ray crystal structures of bridged porphyrins (1980) (8)
- Biosynthesis of porphyrins and related macrocycles. Part 47.1,2 Synthesis and chemistry of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis (1998) (8)
- Biosynthesis of vitamin B12: the preparative multi-enzyme synthesis of precorrin-3A and 20-methylsirohydrochlorin (a 2,7,20-trimethylisobacteriochlorin). (1996) (8)
- Synthesis of (±)-eschscholtzine. The absolute configuration of (–)-argemonine, (–)-eschscholtzine, and related alkaloids (1967) (7)
- The rearrangement process in indole alkaloid biosynthesis (1968) (7)
- Biosynthesis of porphyrins and related macrocycles. Part VII. Synthesis of specifically labelled (14 C1) uroporphyrin-III and of (10,14-13C2)-uroporphyrin-III. Conversion of the latter into (10,14-13C2)protoporphyrin-ix; Biosynthetic significance of its 13C nuclear magnetic resonance spectrum. (1976) (7)
- Alkaloid biosynthesis. Part XI. Studies related to the formation and oxidation of reticuline in morphine biosynthesis (1968) (7)
- A novel stereoselective synthesis of the macrocycle of haem d1 that establishes its absolute configuration as 2R,7R (1993) (7)
- N-Benzoyl-L-phenylalaninol from Catharanthus pusillus (Murr.) G. Don = Vinca pusilla Murr. (1965) (7)
- The constitution of androcymbine (1965) (7)
- Biosynthesis of the pigments of life: Structure and mode of action of a novel enzymatic cofactor (1989) (7)
- Biosynthesis of vitamin B12: origin of the hydrogen atoms at C-18 and C-19 (1984) (7)
- Biosynthesis of schelhammeridine: Mode of specific incorporation of [2-14C]tyrosine (1975) (7)
- Chemical and enzymic studies on biosynthesis of the natural porphyrin macrocycle: Formation and role of unrearranged hydroxymethylbilane and order of assembly of the pyrrole rings (1979) (7)
- The synthesis of 2′: 3′: 2″: 3″-tetramethoxy-1: 2-4: 5-dibenzocyclohepta-1: 4-dienes and related compounds (1955) (7)
- 880. Pavine. Part III. Related synthetic work (1958) (7)
- The Bakerian Lecture, 1984 Biosynthesis of the pigments of life (1985) (7)
- Biosynthesis. Part 24. Speculative incorporation experiments with 1-benzylisoquinolines and a logical approach via C6–C2 and C6–C3 precursors to the biosynthesis of hasubanonine and protostephanine (1981) (7)
- On the biosynthesis of isothebaine (1965) (7)
- Biosynthesis of cactus alkaloids. (1967) (7)
- Enzymic formation of the type-III prophyrin macrocycle from unrearranged AP·AP pyrromethane (1977) (7)
- Stereochemical studies concerning the biosynthesis of narcotine, protopine, and chelidonine (1967) (7)
- Biosynthesis of vitamin B12: isolation and proof of structure of 3-episirohydrochlorin (1979) (7)
- 104. Studies on specific chemical fission of peptide links. Part III. Fission of peptides containing one glutamic acid residue (1961) (7)
- Biosynthesis of porphyrins and related macrocycles. Part 22. Vitamin B12: studies on the chlorin, Faktor-I, and the detection of 3-epi-Faktor-I (1983) (6)
- Studies of enzyme-mediated reactions. Part 15. Stereochemical course of the formation of γ-aminobutyric acid (GABA) by decarboxylation of (2S)-glutamic acid with glutamate decarboxylase from Escherichia coli (1982) (6)
- Biosynthesis of colchicine from a 1-phenethylisoquinoline (1966) (6)
- Studies of enzyme-mediated reactions. Part 14. Stereochemical course of the formation of cadaverine by decarboxylation of (2S)-lysine with lysine decarboxylase (E.C. 4.1.1.18) from Bacillus cadaveris (1982) (6)
- Structure, synthesis, and stereochemistry of deoxytubulosine (1965) (6)
- Alkaloid biosynthesis. XII. The biosynthesis of narcotine. (1968) (6)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 10. Construction of the east and west building blocks for synthesis of isobacteriochlorins (1992) (6)
- Application of spin-echo techniques to the determination of 13C labeling using proton NMR spectroscopy (1983) (6)
- 542. Ipecacuanha alkaloids. Part III. The stereochemistry at positions 1′ and 10 of emetine (1959) (6)
- A new procedure for the reduction of α,β-unsaturated pyrrolidinones to 2H-pyrroles and 1H-pyrroles based on initial activation by N-nitrosation (1996) (6)
- Alangiside: a monoterpenoid lactam (1971) (6)
- Biosynthesis of vitamin B12: use of specific 13C-labelling for structural studies on factor IV (1994) (6)
- Biosynthesis of porphyrins and related macrocycles. Part 49.1 Exploration of synthetic routes to analogues of the spiro-intermediate for porphyrin biosynthesis (1998) (6)
- Hydroxylation at saturated carbon: haemanthamine (1971) (6)
- 1-phenethylisoquinoline alkaloids. 1. Structure and synthesis of (-)-melanthioidine, a bisphenethylisoquinoline alkaloid. (1967) (6)
- 346. Ipecacuanha alkaloids. Part I. Fractionation studies and the isolation of two new alkaloids (1959) (6)
- Tracer studies on β-sitosterol (1964) (6)
- The stereochemistry and absolute configuration of narcotine (1964) (6)
- Studies of enzyme-mediated reactions. 3. Stereoselective labelling at C-2 of tyramine: stereochemistry of hydroxylation at saturated carbon. (1973) (5)
- Biosynthesis of homoaporphines (1969) (5)
- Synthetic studies relevant to biosynthetic research on vitaminB12. Part 12.1 Modification of theperiphery of chlorins and isobacteriochlorins (1997) (5)
- Recent biosynthetic researches on vitamin B12 (1979) (5)
- Chapter 20 The Imidazole Alkaloids (1953) (5)
- Synthesis along biosynthetic pathways. Part 2. Synthesis of protostephanine (1981) (5)
- Biosynthesis. Part 25. Proof that hasubanonine and protostephanine are biosynthesised from the 1-benzylisoquinoline system (1981) (5)
- Biosynthesis of porphyrins and related macrocycles. Part 12. Vitamin B12: studies with 1-methylbilanes (1979) (5)
- Enzymic formation of a tricarboxylic porphyrin and protoporphyrin-XIII from coprogen-IV (1976) (5)
- 1-phenethylisoquinoline alkaloids. IV. Isolation, structural elucidation, and synthesis of c-homoaporphines. (1974) (5)
- Biosynthetic derivation of hasubanonine and protostephanine from the 1-benzylisoquinoline system (1977) (5)
- Preparation of [4R-3H]NADH, [4R-3H]NADPH and the corresponding 4S-isomers all with substantial specific activities (1993) (5)
- 674. Studies of the structure of emetine. Part IV. Elucidation of the structure of emetine (1949) (5)
- Biosynthesis of vitamin B12: the multi-enzyme synthesis of precorrin-4 and factor IV. (1997) (5)
- The discovery of nature's biosynthetic pathways (1978) (5)
- Stereospecificity in the biosynthesis of papaverine (1977) (5)
- Biosynthesis of porphyrins and related macrocycles. Part 51.1,2 Proof that a reductive step occurs during the biosynthesis of vitamin B12 by the microaerophilic organism, Propionibacterium shermanii (1999) (5)
- Studies of enzyme-mediated reactions. Part II. Experiments on the dismutation of aldehyde to alcohol and carboxylic acid by the complex of liver alcohol dehydrogenase and NAD. (1979) (5)
- Constitution of ipecoside: a monoterpenoid isoquinoline (1967) (4)
- Assignment of 13C-signals from the meso-carbons by syntheses of 13C-protoporphyrin-IX dimethyl esters (1973) (4)
- Isolation, crystallisation, and synthesis of the dimethyl ester of porphyrin a, the iron-free prosthetic group of cytochrome c oxidase (1985) (4)
- Structure of dicyano-15-norcobyrinic acid heptamethyl ester (1989) (4)
- Stereochemical studies on the proposed spiro intermediate for the biosynthesis of the natural porphyrins: determination by a novel X-ray method of the absolute configuration of the spirolactam which inhibits cosynthetase (1995) (4)
- Further evidence regarding the structure of emetine (1949) (4)
- Biosynthesis of porphyrins and related macrocycles. Part 14. Studies with [14C]isoporphobilinogen and four isomeric labelled pyrromethanes: specific conversion of the unrearranged pyrromethane NH3.AP.AP into haem and protoporphyrin-IX (1981) (4)
- Proof that the biosynthesis of vitamin B12 involves a reduction step in an anaerobic as well as an aerobic organism (1993) (4)
- The constitution of emetine (1949) (4)
- Selectivity in the rearrangement of a di(pyrrolylmethyl)-2H-pyrrole (1987) (4)
- Biosynthesis of corrins: the C-methylation steps (1974) (4)
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 11. Modification of the east and west building blocks and study of different assembly methods for synthesis of isobacteriochlorins (1992) (4)
- Biosynthesis of porphyrins and related macrocycles. IV. Synthesis of isomeric aminomethylpyrromethanes for biosynthetic study. (1974) (4)
- 698. Ipecacuanha alkaloids. Part VI. The absolute stereochemistry at position 1 of emetine by chemical correlation with the natural amino-acids (1960) (4)
- Melanthioidine: a second 1-phenethylisoquinoline alkaloid (1965) (4)
- Biosynthesis of porphyrins and related macrocycles. Part 15. Chemical and enzymic formation of uroporphyrinogen isomers from unrearranged aminomethylpyrromethane: separation of isomeric coproporphyrin esters (1982) (4)
- Biosynthesis of porphyrins and related macrocycles. Part 44. Synthetic and stereochemical studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins (1996) (4)
- Stereochemistry of dehydrogenation catalysed by the amine oxidase from pea seedlings (E.C.1.4.3.5.) (1974) (4)
- Biosynthesis of vitamin B12: use of a single 13C label in the macrocycle to confirm C-11 methylation in precorrin-6x (1992) (4)
- Biosynthesis. Part XX. Biosynthesis of c-homoaporphines in Kreysigia multiflora (1974) (4)
- Ipecacuanha alkaloids. Part VIII. Chemical correlation of the indole and Ipecacuanha alkaloids (1968) (4)
- Model studies on the type-III porphyrin rearrangement: synthesis and chemistry of pyrrolylmethylpyrrolenines and related systems (1984) (4)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 16. PROOF THAT THE SINGLE INTRAMOLECULAR REARRANGEMENT LEADING TO NATURAL PORPHYRINS (TYPE‐III) OCCURS AT THE TETRAPYRROLE LEVEL (1982) (3)
- Biosynthesis of vitamin B12: studies of the oxidative and lactone-forming steps by 18O-labelling (1994) (3)
- Biosynthesis of porphyrins and related macrocycles. Part 52. Synthesis of (11-S)-[11-2H1]porphobilinogen and the (11R)-enantiomer for stereochemical studies on hydroxymethylbilane synthase (porphobilinogen deaminase) (1999) (3)
- Orientalinone, dihydro-orientalinone, and salutaridine from Papaver orientale: related tracer experiments (1966) (3)
- Biosynthetic and synthetic studies on the pigments of life (1989) (3)
- Recent researches on indole alkaloids (1963) (3)
- Synthesis and X-ray structure analysis of 13,17-bis(2-methoxycarbonylethyl)-12,18-bis(methoxycarbonylmethyl)-2,2,8,8, 20-pentamethylisobacteriochlorin (1994) (3)
- Biosynthesis of morphine: formation of morphine from norlaudanosoline. (1960) (3)
- Stereochemical course of hydroxylation of dopamine by dopamine-β-hydroxylase (EC1.14.17.1) (1974) (3)
- RESEARCHES ON THE BIOSYNTHESIS OF PORPHYRINS (1971) (3)
- Biosynthesis of vitamin B12: preparation of specifically deuteriated heptamethyl dicyanocobyrinate for study by 2H n.m.r. spectroscopy (1982) (3)
- Cytochrome C oxidase: isolation, crystallisation, and synthesis of porphyrin a dimethyl ester (1977) (3)
- Chapter 15 Alkaloids of Calabash Curare and Strychnos Species (1965) (3)
- Biosynthesis. Part 30. Colchicine: Studies on the Ring Expansion Step Focusing on the Fate of the Hydrogens at C-4 of Autumnaline. (1999) (3)
- Research on alkaloids, in retrospect and in prospect (1961) (3)
- Proof that acetic acid is extruded during biosynthesis of vitamin B12 in Pseudomonas denitrificans (1995) (3)
- Biosynthesis of porphyrins and related macrocycles. Part 11. Studies on biosynthesis of the phytyl chain of chlorophyll a by use of carbon-13 (1977) (3)
- SYNTHETIC STUDIES RELEVANT TO BIOSYNTHETIC RESEARCH ON VITAMIN B12. PART 3. AN APPROACH TO ISOBACTERIOCHLORINS VIA NITRONES (1985) (3)
- Further evidence concerning the biosynthesis of indole alkaloids and quinine (1966) (3)
- Biosynthesis. Part 29. Colchicine: Studies on the Ring Expansion Step Focusing on the Fate of the Hydrogens at C‐3 of Autumnaline. (1999) (3)
- Biosynthesis. Part 27. Colchicine: Studies of the Phenolic Oxidative Coupling and Ring-Expansion Processes Based on Incorporation of Multiply Labeled 1-Phenethylisoquinolines. (2010) (3)
- Factor F430 from Methanogenic Bacteria: Absolute Configuration. (1986) (3)
- B12‐Biosynthesis in an Aerobic Organism: How the Pathway was Elucidated (2007) (3)
- The structure of kreysiginine (alkaloid CC-21) (1968) (3)
- Biosynthesis of porphyrins and related macrocycles. Part 53. Stereochemical studies on the enzymic formation of hydroxymethylbilane, the precursor of uroporphyrinogen III (1999) (2)
- Biosynthesis. Part 23. Degradative studies on the alkaloids hasubanonine and protostephanine from Stephania japonica (1981) (2)
- S 12. Studies on the structure of emetine. Part II. Oxidation with mercuric acetate, and the properties of rubremetinium salts (1949) (2)
- Biosynthesis of vitamin B12 : the fate of 8-H as precorrin-2 is enzymically converted into cobyrinic acid (1992) (2)
- Alkylation and acylation of 5-phenylsulphonyl- and 5-cyanobutyrolactones (1992) (2)
- New intermediates in the B12 pathway. (1994) (2)
- Recent researches on the biosynthesis of natural products (1977) (2)
- Synthesis of protostephanine by a route related to the biosynthetic pathway (1968) (2)
- Biosynthesis of protoporphyrin-IX from coproporphyrinogen-III (1972) (2)
- Biosynthesis. Part 28. Colchicine: Definition of Intermediates Between O‐Methylandrocymbine and Colchicine and Studies on Speciosine. (2010) (2)
- Alkaloids of calabash curare: the structure of macusine-B. (1961) (2)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 51. Proof that a Reductive Step Occurs During the Biosynthesis of Vitamin B12 by the Microaerophilic Organism, Propionibacterium shermanii. (1999) (2)
- Role of codeinone in the biosynthesis of morphine alkaloids (1967) (2)
- Selenomethylpyrroles: their use for synthesis of dipyrrylmethanes (dipyrrins), tripyranes and bilanes (1991) (2)
- Biosynthesis of vitamin B12: preparation of 12-methylisobacteriochlorins and related systems (1986) (2)
- S 11. Studies on the structure of emetine. Part I. The Hofmann degradation (1949) (2)
- Syntheses relevant to vitamin B12 biosynthesis: the malate route to (–)-ring-B imide and synthesis of the 2,7,20-trimethylisobacteriochlorin (1989) (1)
- Biosynthesis of terpenoid alkaloids. (1969) (1)
- The constitutions of fruticosine and fruticosamine (1966) (1)
- Biosynthesis of natural porphyrins: further experiments with hydroxymethylbilane (1980) (1)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 17. CHEMICAL AND ENZYMIC TRANSFORMATION OF ISOMERIC AMINOMETHYLBILANES INTO UROPORPHYRINOGENS: PROOF THAT UNREARRANGED BILANE IS THE PREFERRED ENZYMIC SUBSTRATE AND DETECTION OF (1983) (1)
- Biosynthesis of vitamin B12: formation of pyrrocorphins by peripheral C-methylation of precorrin-3 octamethyl ester (1990) (1)
- The absolute configuration of (-)-argemonine. (1967) (1)
- -benzoyl--phenylalaninol from (Murr.) G. Don (= Murr.) (1965) (1)
- Biosynthesis of vitamin B12: does 51-norcobyrinic acid or 151-norcobyrinic acid act as a precursor of cobyrinic acid? (1990) (1)
- The Reaction of N‐Magnesium Derivatives of Pyrroles with N‐Mesylchloromethylpyrroles: A Synthesis of Dipyrrylmethanes. (1999) (1)
- Ideas and experiments in biosynthesis. (2008) (1)
- Vitamin B12. How the Problem of Its Biosynthesis was Solved (1995) (1)
- CHAPTER 11 – BIOSYNTHESIS OF SOME ALKALOIDS BASED UPON AROMATIC PRECURSORS (1966) (1)
- 1-PHENETHYLISOQUINOLINE ALKALOIDS PART 4, ISOLATION, STRUCTURAL ELUCIDATION, AND SYNTHESIS OF C-HOMOAPORPHINES (1974) (1)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 4. Development of the Photochemical Route to Isobacteriochlorins. (1987) (1)
- Stereochemical and Biosynthetic Studies on the Pigments of Life (1988) (1)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 5. Synthesis of (RS)‐Ring‐B Imide (1987) (1)
- The rubremetinium and rubremetaminium cations (1966) (1)
- Alkaloid biosynthesis. XVI. Colchicine: origin of the tropolone ring and studies with the C 6 -C 3 -C 6 -C 1 system. (1972) (1)
- Biosynthesis of vitamin B12: regio-control in peripheral C-methylation of 20-methylpyrrocorphins carrying ester side chains (1989) (1)
- Haem d1: Development of a New Coupling Procedure Leading to the Synthesis of Isobacteriochlorins. (2010) (1)
- Biosynthesis of colchicine. (1960) (1)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES PART 4, SYNTHESES OF ISOMERIC AMINOMETHYLPYRROMETHANES FOR BIOSYNTHETIC STUDY (1974) (1)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 6. Synthesis of Chlorins by a Photochemical Approach. (1988) (1)
- Biosynthesis of vitamin B12: synthesis and peripheral C-methylation of pyrrocorphins carrying ester side chains (1989) (1)
- STUDIES OF ENZYME-MEDIATED REACTIONS. PART 12. STEREOCHEMICAL COURSE OF THE DECARBOXYLATION OF (2S)-TYROSINE TO TYRAMINE BY MICROBIAL, MAMMALIAN, AND PLANT SYSTEMS (1980) (1)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 45. Determination by a Novel X‐Ray Method of the Absolute Configuration of the Spiro Lactam Which Inhibits Uroporphyrinogen III Synthase ( Cosynthetase). (1997) (1)
- Biosynthesis of porphyrins and related macrocycles, Part 43. Isolation and characterization of intermediates of coenzyme B12 biosynthesis, a cobyrinic acid triamide, the a,c-diamide and their Co-(5'-deoxy-5'-adenosyl) derivatives, from Propionibacterium shermanii. (1995) (1)
- Biosynthesis of B12 in the aerobic organism Pseudononas denitrificans. (1999) (1)
- THE ABSOLUTE STEREOCHEMISTRY OF NARCOTINE AND NARCOTOLINE. (1965) (1)
- Biosynthesis of vitamin B12: incorporation of (11S)-[11-2H1-] and (11R)-[11-2H1]porphobilinogen into sirohydrochlorin and 2,7,20-trimethylisobacteriochlorin (1990) (1)
- Alkaloid biosynthesis. 18. Biosynthesis of colchicine from the 1-phenethylisoquinoline system. (1972) (1)
- The total synthesis ofdl-Rubremetinium bromide (1950) (1)
- STUDIES OF ENZYME‐MEDIATED REACTIONS PART 3, STEREOSELECTIVE LABELLING AT C‐2 OF TYRAMINE, STEREOCHEMISTRY OF HYDROXYLATION AT SATURATED CARBON (1973) (1)
- Isomerization of (Z)-Arenediazo Thioethers on Aldolase and Model Compounds (1977) (0)
- STUDIES ON THE BIOGENESIS OF INDOLE ALKALOIDS. SYNTHESIS AND FEEDING OF RADIOACTIVELY LABELED MONOTERPENE ALDEHYDES (1982) (0)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 13. STRUCTURE OF THE E PROTOPORPHYRIN ISOMER DERIVED FROM COPROPORPHYRINOGEN IV BY THE ACTION OF BEEF-LIVER COPROPORPHYRINOGENASE: SYNTHESIS OF PROTOPORPHYRIN XIII (1980) (0)
- Selenomethylpyrroles: Their Use for Synthesis of Dipyrrylmethanes ( Dipyrrins), Tripyranes and Bilanes. (1991) (0)
- Alkylation and Acylation of 5‐Phenylsulfonyl‐ and 5‐Cyanobutyrolactones. (1993) (0)
- Ipecacuanha alkaloids. 8. Chemical correlation of the indole and ipecacuanha alkaloids. (1968) (0)
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- STEREOCHEMICAL COURSE OF HYDROXYLATION OF DOPAMINE BY DOPAMINE-BETA-HYDROXYLASE (EC1.14.17.1) (1974) (0)
- Enzymic synthesis of labelled chiral substances. (1985) (0)
- STUDIES ON THE BIOGENESIS OF INDOLE ALKALOIDS. SYNTHESIS AND FEEDING OF RADIOACTIVELY LABELED HYDROXYLOGANIN DERIVATIVES (1982) (0)
- Haem d1: Stereoselective Synthesis of the Macrocycle to Establish Its Absolute Configuration as 2R, 7R. (1997) (0)
- Tetrapyrroles: The Pigments of Life (2001) (0)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 41. Fate of Oxygen Atoms as Precorrin-2 Carrying Eight Labelled Carboxyl Groups ( 13C18O2H) is Enzymatically Converted into Cobyrinic Acid. (1994) (0)
- STUDIES OF ENZYME-MEDIATED REACTIONS. PART 13. STEREOCHEMICAL COURSE OF THE FORMATION OF HISTAMINE BY DECARBOXYLATION OF (2S)-HISTIDINE WITH ENZYMES FROM CLOSTRIDIUM WELCHII AND LACTOBACILLUS 30A (1980) (0)
- SYNTHESES RELEVANT TO VITAMIN B12 BIOSYNTHESIS: SYNTHESIS OF (.+-.)-FAKTOR-1 OCTAMETHYL ESTER (1985) (0)
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- Biosynthesis of Porphyrins and Related Macrocycles. Part 44. Synthetic and Stereochemical Studies on the Proposed Spiro Intermediate for Biosynthesis of the Natural Porphyrins. (1997) (0)
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- Preface to the Special Issue of HETEROCYCLES in Honour of Dr. Arnold R. Brossi (1994) (0)
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- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 18. PROOF BY SPECTROSCOPY AND SYNTHESIS THAT UNREARRANGED HYDROXYMETHYLBILANE IS THE PRODUCT FROM DEAMINASE AND THE SUBSTRATE FOR COSYNTHETASE IN THE BIOSYNTHESIS OF UROPORPHYRI (1983) (0)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES PART 1, SYNTHESIS OF (14)C-LABELLED PYRROMETHANES (1973) (0)
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- Stereochemical Studies on Porphyrin a: Assignment of the Absolute Configuration of a Model Porphyrin by Degradation. (1987) (0)
- Alkaloids of calabash curare and Strychnos species. Part IV. Caracurine-II (1967) (0)
- STUDIES OF ENZYME-MEDIATED REACTIONS. PART 10. STEREOCHEMICAL COURSE OF THE DEHYDROGENATION OF STEREOSPECIFICALLY LABELED 1-AMINOHEPTANES BY THE AMINE OXIDASE FROM RAT LIVER MITOCHONDRIA (EC 1.4.3.4) (1980) (0)
- Alkaloid biosynthesis. XVII. The structure and chemistry of androcymbine. (1972) (0)
- Alkaloid biosynthesis. IX. The ipecacuanha alkaloids. (1965) (0)
- THE CHEMISTRY OF PYRROLIC COMPOUNDS. PART 56. PORPHYRINS AND RELATED MACROCYCLES. PART 24. ISOLATION, CRYSTALLIZATION, AND SYNTHESIS OF THE DIMETHYL ESTER OF PORPHYRIN A, THE IRON-FREE PROSTHETIC GROUP OF CYTOCHROME C OXIDASE (1985) (0)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 10. Construction of the East and West Building Blocks for Synthesis of Isobacteriochlorins. (1992) (0)
- TOTAL SYNTHESIS OF (.+-.)-BONELLIN DIMETHYL ESTER (1984) (0)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 14. STUDIES WITH CARBON-14 LABELED ISOPORPHOBILINOGEN AND FOUR ISOMERIC LABELED PYRROMETHANES: SPECIFIC CONVERSION OF THE UNREARRANGED PYRROMETHANE INTO HEME AND PROTOPORPHYRIN- (1982) (0)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 49. Exploration of Synthetic Routes to Analogues of the Spiro‐Intermediate for Porphyrin Biosynthesis. (1998) (0)
- BIOSYNTHESIS. PART 24. SPECULATIVE INCORPORATION EXPERIMENTS WITH 1-BENZYLISOQUINOLINES AND A LOGICAL APPROACH VIA C6-C2 AND C6-C3 PRECURSORS TO THE BIOSYNTHESIS OF HASUBANONINE AND PROTOSTEPHANINE (1981) (0)
- A SYNTHETIC ROUTE TO THE ISOBACTERIOCHLORINE STRUCTURE TYPE (1979) (0)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 47. Synthesis and Chemistry of 2H‐Pyrroles (Pyrrolenines) Related to the Proposed Spiro‐Intermediate for Porphyrin Biosynthesis. (1998) (0)
- STUDIES OF ENZYME-MEDIATED REACTIONS PART 5, SYNTHESIS OF (13S)- AND (13R)-(13-(3)H1)SCOULERINE FROM STEREOSPECIFICALLY LABELLED (R)- AND (S)-(ALPHA-(3)H1)BENZYL ALCOHOLS, STEREOCHEMISTRY OF ENZYMIC REACTIONS AT SATURATED BENZYLIC CAR (1975) (0)
- Bio-organic mechanisms by T.C. Bruice and S. J. Benkovic, W.A. Benjamin, Inc., New York, 1966. Vol. I, 362 pp., $22.50, and Vol. II, 419 pp., $25.00 (1968) (0)
- Alkaloid biosynthesis. 13. The structure, stereochemistry, and biosynthesis of loganin. (1969) (0)
- ASSIGNMENT OF (13)C-SIGNALS FROM THE MESO-CARBONS BY SYNTHESES OF (13)C-PROTOPORPHYRIN-IX DIMETHYL ESTERS (1973) (0)
- Bio-Organic Mechanisms, T.C. Bruice, S.J. Benkovic. W. A. Benjamin, Inc., New York (1966), 362, $22.50, and Vol. II, 419 pp., $25.00 (1968) (0)
- Researches into the structure of emetine (1949) (0)
- (3S,4S)-4-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3-methyl-2,5-dithioxopyrrolidine (1989) (0)
- Studies of Enzyme-Mediated Reactions. Part 16. Stereochemical Course of the Formation of 5-Hydroxytryptamine (Serotonin) by Decarboxylation of (2S)-5-Hydroxytryptophan with the Aromatic L-Amino Acid Decarboxylase (E.C. 4.1.1.28) from (1990) (0)
- Biosynthesis of Vitamin B12: Biosynthetic and Synthetic Researches (1990) (0)
- 1-Mesyl-4-[2-(methoxycarbonyl)ethyl]-3-(methoxycarbonyl)methyl-N,N-dimethylpyrrole-2-carboxamide (1989) (0)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 11. Modification of the East and West Building Blocks and Study of Different Assembly Methods for Synthesis of Isobacteriochlorins. (1992) (0)
- Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 8. Synthesis of (.+-.)-Faktor-I Octamethyl Ester (V). (1988) (0)
- BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES. PART 25. SYNTHESIS OF ANALOGS OF COPROPORPHYRINOGEN-III AND STUDIES OF THEIR INTERACTION WITH COPROPORPHYRINOGEN-III OXIDASE FROM EUGLENA GRACILIS (1985) (0)
- SYNTHESIS ALONG BIOSYNTHETIC PATHS. PART 2. SYNTHESIS OF PROTOSTEPHANINE (1981) (0)
- Chirally tritiated and deuteriated compounds in studies of biosynthesis (1988) (0)
- SYNTHETIC STUDIES RELATED TO MYOGLOBIN- SYNTHESES OF BRIDGED PORPHYRIN SYSTEMS (1977) (0)
- BIOSYNTHESIS. PART 25. PROOF THAT HASUBANONINE AND PROTOSTEPHANINE ARE BIOSYNTHESIZED FROM THE 1‐BENZYLISOQUINOLINE SYSTEM (1981) (0)
- STUDIES OF ENZYME-MEDIATED REACTIONS. PART 11. EXPERIMENTS ON THE DISMUTATION N OF ALDEHYDE TO ALCOHOL AND CARBOXYLIC ACID BY THE COMPLEX OF LIVER ALCOHOL DEHYDROGENASE AND NAD+ (1980) (0)
- Stereochemical Studies on the Proposed Spiro Intermediate for the Biosynthesis of the Natural Porphyrins: Determination by a Novel X‐Ray Method of the Absolute Configuration of the Spirolactam which Inhibits Cosynthetase. (1996) (0)
- BIOSYNTHESIS OF VITAMIN B12. ANALYSIS OF THE PROTON AND CARBON-13 NMR SPECTRA OF HEPTAMETHYL DICYANOCOBYRINATE (COBESTER) (1982) (0)
- Biosynthesis of terpenoid alkaloids. (1970) (0)
- NEW METHODS FOR DEMETALIZATION OF TETRAPYRROLE-TYPE METALLOMACROCYCLES (1984) (0)
- Biosynthesis of Porphyrins and Related Macrocycles. Part 40. Synthesis of a Spiro-Lactam (I) Related to the Proposed Spiro-Intermediate for Porphyrin Biosynthesis: Inhibition of Cosynthetase. (1994) (0)
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