Alan R. Shuldiner

Alan R. Shuldiner's AcademicInfluence.com Rankings

Alan R. Shuldiner

Philosophy

#6306

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#9321

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#3482

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#4647

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philosophy Degrees

Alan R. Shuldiner

Biology

#8556

World Rank

#11653

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Genetics

#858

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#952

Historical Rank

biology Degrees

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Philosophy
Biology

Alan R. Shuldiner's Degrees

PhD Human Genetics Johns Hopkins University
Doctorate Medicine Johns Hopkins University

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Alan R. Shuldiner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes (2012) (1839)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
Newly identified loci that influence lipid concentrations and risk of coronary artery disease (2008) (1626)
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. (2009) (1481)
New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (2012) (1045)
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits (2011) (842)
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update (2013) (837)
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. (2006) (806)
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. (2006) (796)
Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways (2012) (758)
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance (2012) (756)
New loci associated with kidney function and chronic kidney disease (2010) (754)
Omentin Plasma Levels and Gene Expression Are Decreased in Obesity (2007) (701)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection (2008) (631)
Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. (1995) (603)
Genetic Variation in the β3-Adrenergic Receptor and an Increased Capacity to Gain Weight in Patients with Morbid Obesity (1995) (588)
Unique lipoprotein phenotype and genotype associated with exceptional longevity. (2003) (562)
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease (2017) (537)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies (2010) (477)
Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels (2011) (476)
Molecular Scanning of the Human Peroxisome Proliferator Activated Receptor γ (hPPARγ) Gene in Diabetic Caucasians: Identification of a Pro12Ala PPARγ2 Missense Mutation (1997) (469)
Implementing genomic medicine in the clinic: the future is here (2013) (463)
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study (2016) (445)
Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450–2C19 (CYP2C19) Genotype and Clopidogrel Therapy (2011) (429)
New gene functions in megakaryopoiesis and platelet formation (2011) (423)
A Protein‐Truncating HSD17B13 Variant and Protection from Chronic Liver Disease (2018) (422)
FTO genotype is associated with phenotypic variability of body mass index (2012) (407)
Common variants in the GDF5-UQCC region are associated with variation in human height (2008) (400)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease. (2016) (372)
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits (2013) (365)
Telomere length is paternally inherited and is associated with parental lifespan (2007) (362)
Seventy-five genetic loci influencing the human red blood cell (2012) (357)
Acute-Phase Serum Amyloid A: An Inflammatory Adipokine and Potential Link between Obesity and Its Metabolic Complications (2006) (337)
A rapid and versatile method to synthesize internal standards for competitive PCR. (1993) (328)
Ethical and Practical Guidelines for Reporting Genetic Research Results to Study Participants: Updated Guidelines from a National Heart, Lung, and Blood Institute Working Group (2010) (324)
Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations. (1998) (322)
Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta. (1993) (319)
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile (2011) (313)
Genetic identification of familial hypercholesterolemia within a single U.S. health care system (2016) (307)
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. (1998) (306)
Polymorphisms in the Transcription Factor 7-Like 2 (TCF7L2) Gene Are Associated With Type 2 Diabetes in the Amish (2006) (306)
Whole-genome association study identifies STK39 as a hypertension susceptibility gene (2009) (300)
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders (2013) (299)
Physical activity and the association of common FTO gene variants with body mass index and obesity. (2008) (294)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure (2020) (288)
Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction (2011) (286)
Resistin, obesity, and insulin resistance--the emerging role of the adipocyte as an endocrine organ. (2001) (282)
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium (2009) (281)
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche (2009) (276)
Genetic loci influencing kidney function and chronic kidney disease (2010) (266)
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (2014) (260)
Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. (1997) (255)
Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program (2010) (244)
Exome sequencing and characterization of 49,960 individuals in the UK Biobank (2020) (244)
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response (2007) (242)
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. (2018) (221)
Comparative studies of resistin expression and phylogenomics in human and mouse. (2003) (215)
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque (2011) (214)
CUBN is a gene locus for albuminuria. (2011) (214)
Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. (1995) (214)
Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention. (2018) (210)
Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor. (2002) (207)
Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans (2006) (206)
Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome (2012) (204)
Genetic evidence of assortative mating in humans (2017) (199)
A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function (2013) (193)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
Global implementation of genomic medicine: We are not alone (2015) (183)
The IGNITE network: a model for genomic medicine implementation and research (2015) (180)
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function (2012) (180)
Identification of Novel Candidate Genes for Type 2 Diabetes From a Genome-Wide Association Scan in the Old Order Amish (2007) (176)
Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study. (2000) (174)
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. (2008) (170)
Heritability of life span in the Old Order Amish. (2001) (167)
Exome sequencing and analysis of 454,787 UK Biobank participants (2021) (166)
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real‐World Implementation (2013) (166)
Pharmacogenomics: Challenges and Opportunities (2006) (162)
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank (2020) (162)
A Central Role for GRB10 in Regulation of Islet Function in Man (2014) (159)
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (153)
Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24. (2003) (151)
Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems (2015) (149)
Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes. (2014) (146)
Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
Directional dominance on stature and cognition in diverse human populations (2015) (144)
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men. (1998) (140)
PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19 (2012) (140)
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes (2000) (138)
The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response (2013) (137)
Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. (2008) (135)
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. (2009) (132)
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. (2017) (132)
Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain. (2001) (130)
The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. (2008) (127)
Adiponectin levels and genotype: a potential regulator of life span in humans. (2008) (127)
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis (2020) (127)
Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank (2019) (126)
Eating behavior in the Old Order Amish: heritability analysis and a genome-wide linkage analysis. (2002) (125)
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference (2002) (125)
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes (2015) (121)
A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride (1997) (118)
Metformin Pharmacogenomics: Current Status and Future Directions (2014) (115)
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems (2017) (115)
Genome-wide association study of kidney function decline in individuals of European descent (2014) (114)
Linkage of plasma adiponectin levels to 3q27 explained by association with variation in the APM1 gene. (2005) (111)
A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans. (1998) (111)
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. (2002) (107)
Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program (2008) (106)
Rethinking the genetic basis for comorbidity of schizophrenia and type 2 diabetes (2010) (105)
Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program (2012) (105)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies (2012) (102)
QTL influencing blood pressure maps to the region of PPH1 on chromosome 2q31-34 in Old Order Amish. (2000) (102)
A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians. (2003) (101)
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation (2016) (100)
The Pro12Ala variant of peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) is associated with measures of obesity in Mexican Americans (2000) (99)
Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. (2005) (98)
COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan (2009) (98)
Variable Bone Fragility Associated With an Amish COL1A2 Variant and a Knock-in Mouse Model (2009) (97)
Hybrid DNA artifact from PCR of closely related target sequences. (1989) (97)
SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study. (2002) (97)
Genome-wide scan of obesity in the Old Order Amish. (2001) (97)
Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study. (1999) (96)
Chromosomal localization and partial genomic structure of the human peroxisome proliferator activated receptor-gamma (hPPAR gamma) gene. (1997) (96)
Fatty acid binding protein-2 gene variants and insulin resistance: gene and gene-environment interaction effects. (2002) (96)
Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish. (2008) (93)
Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study (2009) (92)
Common Genetic Variation in the 3′-BCL11B Gene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk: The AortaGen Consortium (2012) (91)
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes (2018) (91)
Interactions Between Variants in the β3-Adrenergic Receptor and Peroxisome Proliferator–Activated Receptor-γ2 Genes and Obesity (2001) (90)
Genotyping: one piece of the puzzle to personalize antiplatelet therapy. (2010) (90)
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to cyp 2c19*2 genotype: first experience in patients (2010) (89)
Searching for human longevity genes: the future history of gerontology in the post-genomic era. (2001) (88)
Pancreatic thread protein is mitogenic to pancreatic-derived cells in culture. (1996) (88)
Associations between Genetic Variants in the NOS1AP (CAPON) Gene and Cardiac Repolarization in the Old Order Amish (2007) (87)
Genetic Variation in PEAR1 Is Associated With Platelet Aggregation and Cardiovascular Outcomes (2013) (87)
Platelet aggregation pathway. (2011) (87)
Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabetes (TRIPOD) study. (2004) (86)
Implementation of pharmacogenetics: The University of Maryland personalized anti‐platelet pharmacogenetics program (2014) (86)
Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish. (2005) (86)
Paraoxonase 1 (PON1) Gene Variants Are Not Associated With Clopidogrel Response (2011) (86)
Clopidogrel: A Case for Indication‐Specific Pharmacogenetics (2012) (85)
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity (2021) (85)
Does having children extend life span? A genealogical study of parity and longevity in the Amish. (2006) (84)
Genetic Variation at NCAN Locus Is Associated with Inflammation and Fibrosis in Non-Alcoholic Fatty Liver Disease in Morbid Obesity (2013) (83)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations (2021) (83)
The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy. (2011) (82)
Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver (2004) (82)
Serum 25-Hydroxyvitamin D Levels Are Not Associated with Subclinical Vascular Disease or C-Reactive Protein in the Old Order Amish (2009) (80)
Genotype-based changes in serum uric acid affect blood pressure. (2012) (79)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
The role of peroxisome proliferator-activated receptor gamma in diabetes and obesity (2002) (78)
Association of Single Nucleotide Polymorphisms on Chromosome 9p21.3 With Platelet Reactivity: A Potential Mechanism for Increased Vascular Disease (2010) (78)
Determinants of Coronary Artery and Aortic Calcification in the Old Order Amish (2007) (76)
Genes encoding receptors for insulin and insulin-like growth factor I are expressed in Xenopus oocytes and embryos. (1991) (76)
A genome-wide scan of serum lipid levels in the Old Order Amish. (2004) (76)
The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program (2012) (74)
Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference (2012) (74)
The relationship between parity and bone mineral density in women characterized by a homogeneous lifestyle and high parity. (2005) (73)
Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish. (2010) (73)
Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. (2001) (73)
Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women (2007) (72)
The CYP2C19*17 variant is not independently associated with clopidogrel response (2013) (72)
Association of the Vitamin D Metabolism Gene CYP24A1 With Coronary Artery Calcification (2010) (71)
Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study. (2003) (69)
Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish. (2004) (69)
Genetic and environmental influences on bone mineral density in pre- and post-menopausal women (2005) (68)
Associations of autozygosity with a broad range of human phenotypes (2019) (68)
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. (2012) (67)
Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed-Pharmacogenomics (2013) (66)
Association between obesity and a polymorphism in the β1-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women (2002) (64)
Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant. (2000) (64)
Mutations in Gng3lg and AGPAT2 in Berardinelli-Seip congenital lipodystrophy and Brunzell syndrome: phenotype variability suggests important modifier effects. (2004) (61)
Stroke Genetics Network (SiGN) Study: Design and Rationale for a Genome-Wide Association Study of Ischemic Stroke Subtypes (2013) (60)
Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals (2021) (59)
Variation in the Lamin A/C Gene: Associations With Metabolic Syndrome (2004) (58)
PCR-induced (ligase-free) subcloning: a rapid reliable method to subclone polymerase chain reaction (PCR) products. (1990) (58)
Quantitative Trait Loci for BMD Identified by Autosome‐Wide Linkage Scan to Chromosomes 7q and 21q in Men from the Amish Family Osteoporosis Study (2006) (58)
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2020) (58)
The association of coronary artery calcification and carotid artery intima-media thickness with distinct, traditional coronary artery disease risk factors in asymptomatic adults. (2008) (57)
The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish. (2005) (56)
The Gln223 Arg and Lys656 Asn Polymorphisms in the Human Leptin Receptor Do Not Associate With Traits Related to Obesity (1997) (56)
Obesity gene variant and elite endurance performance. (2001) (56)
Does genetic testing for obesity influence confidence in the ability to lose weight? A pilot investigation. (2001) (56)
TM6SF2 rs58542926 impacts lipid processing in liver and small intestine (2017) (55)
Obesity-related phenotypes and the beta3-adrenoceptor gene variant in postmenopausal women. (1999) (55)
The insulin-like growth factor I (IGF-I) gene is expressed in chick embryos during early organogenesis. (1990) (54)
The Pro12Ala variant of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) is associated with measures of obesity in Mexican Americans. (2000) (53)
RNA template-specific PCR: an improved method that dramatically reduces false positives in RT-PCR. (1991) (53)
Association between body fat response to exercise training and multilocus ADR genotypes. (2004) (53)
Monogenic Diabetes in Overweight and Obese Youth Diagnosed with Type 2 Diabetes: The TODAY Clinical Trial (2017) (53)
Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability (2014) (52)
Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). (2009) (52)
Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q (2006) (52)
Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair. (1996) (51)
Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort). (2013) (51)
Habitual sleep/wake patterns in the Old Order Amish: heritability and association with non-genetic factors. (2011) (51)
Profiling and leveraging relatedness in a precision medicine cohort of 92,455 exomes (2017) (51)
Modeled nitrate levels in well water supplies and prevalence of abnormal thyroid conditions among the Old Order Amish in Pennsylvania (2012) (50)
Assessment of sex‐specific genetic and environmental effects on bone mineral density (2004) (50)
Determination of gene dosage by a quantitative adaptation of the polymerase chain reaction (gd-PCR): rapid detection of deletions and duplications of gene sequences. (1994) (50)
Two nonallelic insulin genes in Xenopus laevis are expressed differentially during neurulation in prepancreatic embryos. (1991) (49)
Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia. (1996) (48)
Molecular scanning for mutations in the beta 3-adrenergic receptor gene in Nauruans with obesity and noninsulin-dependent diabetes mellitus. (1996) (48)
Pharmacogenomics: Application to the Management of Cardiovascular Disease (2011) (48)
TCF7L2 variants associate with CKD progression and renal function in population-based cohorts. (2008) (48)
Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey. (1994) (48)
Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients. (2019) (47)
Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program (2012) (47)
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update (2022) (46)
Identification of an Interactive Effect of β3- and α2b-Adrenoceptor Gene Polymorphisms on Fat Mass in Caucasian Women (2001) (46)
The genetics of obesity. (2003) (46)
No effect of the Trp64Arg beta(3)-adrenoceptor gene variant on weight loss, body composition, or energy expenditure in obese, caucasian postmenopausal women. (2002) (45)
TRP64ARG β3-adrenergic receptor and obesity in Mexican Americans (1997) (45)
Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-gamma2 Pro12Ala genotype in men but not in women. (2005) (45)
Evaluation of A2BP1 as an Obesity Gene (2010) (44)
Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels. (2015) (44)
Anti-inflammatory effects of simvastatin on adipokines in type 2 diabetic patients with carotid atherosclerosis (2009) (43)
Xenopus laevis contains two nonallelic preproinsulin genes. cDNA cloning and evolutionary perspective. (1989) (42)
Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes (2021) (41)
Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over again. (2004) (41)
Exploring the genetics of longevity in the Old Order Amish (2005) (40)
FABP2 Ala54Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women. (2007) (40)
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease (2022) (40)
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease (2022) (40)
Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with type 2 diabetes in the old order Amish. (2004) (39)
CYP2C19 Metabolizer Status and Clopidogrel Efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) Study (2015) (39)
A Common Variant in the Telomerase RNA Component Is Associated with Short Telomere Length (2010) (39)
Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension (2018) (38)
The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature (2017) (38)
Isolation and characterization of two different insulins from an amphibian, Xenopus laevis. (1989) (38)
The role of cigarette smoking and statins in the development of postmenopausal osteoporosis: a pilot study utilizing the Marshfield Clinic Personalized Medicine Cohort (2010) (38)
Longevity genes: from primitive organisms to humans. (2003) (38)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2019) (38)
Genomic characterization of the coding region of the human type II 5′-deiodinase gene (1998) (38)
Genomic diagnostics within a medically underserved population: efficacy and implications (2017) (38)
Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity. (2001) (38)
A genome-wide scan for autoimmune thyroiditis in the Old Order Amish: replication of genetic linkage on chromosome 5q11.2-q14.3. (2003) (37)
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
A functional haplotype in EIF2AK3, an ER stress sensor, is associated with lower bone mineral density (2012) (37)
Activating Transcription Factor 6 (ATF6) Sequence Polymorphisms in Type 2 Diabetes and Pre-Diabetic Traits (2007) (37)
Electron emission and luminescence owing to plastic deformation of ionic crystals (1995) (36)
Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort (2019) (36)
Reduced Incidence of Hip Fracture in the Old Order Amish (2003) (36)
Molecular scanning for mutations in the insulin receptor substrate‐1 (IRS‐1) gene in Mexican Americans with Type 2 diabetes mellitus (2000) (36)
Common variants in Mendelian kidney disease genes and their association with renal function. (2013) (35)
Relationship between Vascular Calcification and Bone Mineral Density in the Old-Order Amish (2007) (35)
Insulin response to glucose is lower in individuals homozygous for the Arg 64 variant of the beta-3-adrenergic receptor. (2000) (35)
Consortium ( CPIC ) guidelines for cytochrome P 450-2 C 19 ( CYP 2 C 19 ) genotype and clopidogrel therapy (2011) (35)
Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers (2014) (35)
Hypertrophy‐Associated Polymorphisms Ascertained in a Founder Cohort Applied to Heart Failure Risk and Mortality (2011) (35)
Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes (2007) (34)
Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). (2015) (34)
A recombinant rat regenerating protein is mitogenic to pancreatic derived cells. (2000) (34)
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program (2012) (33)
Variants in ARHGEF11, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians (2007) (33)
A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations (2016) (33)
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program (2012) (33)
Responding to the clopidogrel warning by the US food and drug administration: real life is complicated. (2010) (33)
β3-adrenoceptor gene variant in obesity and insulin resistance (1996) (32)
Accounting for Relatedness in Family Based Genetic Association Studies (2007) (32)
Physical activity and prevention of type 2 diabetes (2003) (32)
Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish (2014) (32)
DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program (2018) (31)
Inactivating Variants in ANGPTL 4 and Risk of Coronary Artery Disease (2016) (31)
Pharmacogenetics and Clopidogrel Response in Patients Undergoing Percutaneous Coronary Interventions (2011) (31)
The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults. (2008) (31)
Mucus sialylation determines intestinal host-commensal homeostasis (2022) (31)
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank (2022) (31)
Trp64Arg Variant of theβ 3-Adrenoceptor and Insulin Resistance in Obese Postmenopausal Women1 (1998) (31)
Evidence that Xenopus laevis contains two different nonallelic insulin-like growth factor-I genes. (1990) (31)
RNA template-specific polymerase chain reaction (RS-PCR): a novel strategy to reduce dramatically false positives. (1990) (31)
The beta3-adrenergic receptor in the obesity and diabetes prone rhesus monkey is very similar to human and contains arginine at codon 64. (1997) (30)
Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib (2014) (30)
Lack of IRS-1 codon 513 and 972 polymorphism in Pima Indians. (1995) (30)
The ABCG8 G574R Variant, Serum Plant Sterol Levels, and Cardiovascular Disease Risk in the Old Order Amish (2013) (30)
Investigations of the Y Chromosome, Male Founder Structure and YSTR Mutation Rates in the Old Order Amish (2007) (30)
American Diabetes Association and JDRF Research Symposium: Diabetes and the Microbiome (2015) (30)
Evidence That Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) on 1q21 is a Type 2 Diabetes Susceptibility Gene in the Old Order Amish (2007) (30)
Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities (2019) (29)
Genetic influences on blood pressure response to the cold pressor test: results from the Heredity and Phenotype Intervention Heart Study (2008) (29)
Differential expression of reg-I and reg-II genes during aging in the normal mouse. (1996) (29)
Expression, purification, and initial characterization of human alanine aminotransferase (ALT) isoenzyme 1 and 2 in High-five insect cells. (2008) (28)
TCF7L2 Polymorphism, Weight Loss and Proinsulin∶Insulin Ratio in the Diabetes Prevention Program (2011) (28)
The common genetic influence over processing speed and white matter microstructure: Evidence from the Old Order Amish and Human Connectome Projects (2016) (28)
Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q (2009) (28)
Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. (2015) (28)
Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits (2012) (28)
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1. (2012) (28)
Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk (2009) (27)
Pharmacogenomics of Anti-platelet Therapy: How much evidence is enough for clinical implementation? (2013) (27)
Glucokinase regulatory protein gene polymorphism affects postprandial lipemic response in a dietary intervention study (2009) (27)
The β3-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos (1997) (27)
Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease (2017) (27)
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. (2014) (27)
Obesity Genes and Gene–Environment–Behavior Interactions: Recommendations for a Way Forward (2008) (27)
Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults. (2016) (26)
No effect of the Trp64Arg β3-adrenoceptor variant on in vivo lipolysis in subcutaneous adipose tissue (1997) (26)
Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. (2012) (26)
Chronotype and seasonality: morningness is associated with lower seasonal mood and behavior changes in the Old Order Amish. (2015) (26)
Genetics of insulin resistance (2002) (26)
An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs (2021) (26)
Living the Good Life? Mortality and Hospital Utilization Patterns in the Old Order Amish (2012) (25)
New progress in adipocytokine research (2003) (25)
Polymorphisms in the Glucokinase-Associated, Dual-Specificity Phosphatase 12 (DUSP12) Gene Under Chromosome 1q21 Linkage Peak Are Associated With Type 2 Diabetes (2006) (25)
Correlation of Circulating MMP-9 with White Blood Cell Count in Humans: Effect of Smoking (2013) (25)
Altered insulin receptor messenger ribonucleic acid splicing in liver is associated with deterioration of glucose tolerance in the spontaneously obese and diabetic rhesus monkey: analysis of controversy between monkey and human studies. (1996) (24)
CYP2C19 genotype and cardiovascular events. (2012) (24)
Familial Hypercholesterolemia and Type 2 Diabetes in the Old Order Amish (2017) (24)
Molecular investigation of age-related changes in mouse endocrine pancreas. (1996) (23)
The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function. (2014) (23)
Pancreatic reg gene expression is inhibited during cellular differentiation. (1997) (23)
Determinants of Blood Pressure Response to Low‐Salt Intake in a Healthy Adult Population (2011) (23)
Genome-Wide Association Scan Identifies Variants near Matrix Metalloproteinase (MMP) Genes on Chromosome 11q21–22 Strongly Associated With Serum MMP-1 Levels (2009) (23)
The CFTR Met 470 Allele Is Associated with Lower Birth Rates in Fertile Men from a Population Isolate (2010) (22)
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium (2020) (22)
Genome‐wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) (2017) (22)
Decreased bone mineral density in subjects carrying familial defective apolipoprotein B-100. (2013) (22)
TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans. (1997) (22)
Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking (2017) (21)
Genetic Effects on Postprandial Variations of Inflammatory Markers in Healthy Individuals (2010) (21)
Mammographic Breast Density—Evidence for Genetic Correlations with Established Breast Cancer Risk Factors (2008) (21)
FABP2 genotype is associated with insulin sensitivity in older women. (2001) (21)
Identification of an interactive effect of beta3- and alpha2b-adrenoceptor gene polymorphisms on fat mass in Caucasian women. (2001) (21)
The two nonallelic insulin-like growth factor-I genes in Xenopus laevis are differentially regulated during development. (1994) (21)
Educational innovations in clinical pharmacogenomics (2016) (21)
Thrombin-induced platelet-fibrin clot strength: Relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes (2013) (21)
Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response. (2017) (21)
The genetic interface between gestational diabetes and type 2 diabetes (2012) (21)
Heritability of complex white matter diffusion traits assessed in a population isolate (2016) (21)
Ligase-free subcloning: a versatile method to subclone polymerase chain reaction (PCR) products in a single day. (1991) (20)
Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease (2020) (20)
Comparison of BMI and Physical Activity Between Old Order Amish Children and Non-Amish Children (2013) (20)
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
Trp64Arg beta3-adrenoceptor: when does a candidate gene become a disease-susceptibility gene? (2001) (20)
CPT1A methylation is associated with plasma adiponectin. (2017) (19)
Differences in prevalence and severity of coronary artery calcification between two non-Hispanic white populations with diverse lifestyles. (2008) (19)
Functional Variants in MBL2 Are Associated With Type 2 Diabetes and Pre-Diabetes Traits in Pima Indians and the Old Order Amish (2010) (19)
Heritability of serum sodium concentration: evidence for sex- and ethnic-specific effects. (2012) (18)
NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. (2017) (18)
Competitive reverse-transcriptase polymerase chain reaction without an artificial internal standard. (1995) (18)
Genetic variation of Glucose Transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) Study (2011) (18)
Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. (2021) (18)
Pharmacogenetic Associations of &bgr;1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes) (2017) (18)
Regenerating (reg) and insulin genes are expressed in prepancreatic mouse embryos. (1996) (18)
Genome sequencing unveils a regulatory landscape of platelet reactivity (2019) (18)
??2- AND ??3-ADRENERGIC RECEPTOR POLYMORPHISMS AND EXERCISE HEMODYNAMICS IN POSTMENOPAUSAL WOMEN (2001) (17)
Cardiovascular pharmacogenomics. (2011) (17)
User-centered design of multi-gene sequencing panel reports for clinicians (2016) (17)
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential (2022) (17)
Genetics of obesity: More complicated than initially thought (2003) (17)
Seasonality of mood and behavior in the Old Order Amish. (2013) (16)
Pro115Gln peroxisome proliferator-activated receptor-gamma and obesity. (2000) (16)
Persistent Staphylococcus aureus Colonization Is Not a Strongly Heritable Trait in Amish Families (2011) (16)
Reversal of Aging‐Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein‐Protein Interfaces (2018) (16)
Oxylipid Profile of Low‐Dose Aspirin Exposure: A Pharmacometabolomics Study (2015) (16)
Prioritizing Approaches to Engage Community Members and Build Trust in Biobanks: A Survey of Attitudes and Opinions of Adults within Outpatient Practices at the University of Maryland (2015) (15)
Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. (2016) (15)
Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture (2007) (15)
Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention (2017) (15)
Expression of the regenerating gene in the pancreas of aging mice. (1994) (15)
Genetic association analysis of SARS-CoV-2 infection in 455,838 UK Biobank participants (2020) (15)
Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement". (2010) (15)
Paraoxonase 1 Q192R variant and clopidogrel efficacy: fact or fiction? (2012) (14)
A Unique Presentation of Infantile-Onset Colitis and Eosinophilic Disease without Recurrent Infections Resulting from a Novel Homozygous CARMIL2 Variant (2019) (14)
Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals (2020) (14)
Beta 3-adrenergic receptor gene variant and lipid metabolism in Pima Indians. (1997) (14)
Germline Mutations in CIDEB and Protection against Liver Disease. (2022) (14)
A novel TUFM homozygous variant in a child with mitochondrial cardiomyopathy expands the phenotype of combined oxidative phosphorylation deficiency 4 (2019) (13)
A Genome-Wide Linkage Scan of Insulin Level–Derived Traits (2007) (13)
A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project (2014) (13)
Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes (2021) (13)
Beta2- and beta3-adrenergic receptor polymorphisms and exercise hemodynamics in postmenopausal women. (2004) (13)
Analysis of the peroxisome proliferator activated receptor γ (PPARγ) gene in HAIRAN syndrome with obesity (2000) (13)
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk (2020) (13)
Erratum to “Comparative studies of resistin expression and phylogenomics in human and mouse” [Biochem. Biophys. Res. Commun. 310 (2003) 927–935] (2003) (12)
On the mechanism of deformation-induced destruction of colour centres (1996) (12)
Pharmacogenomics of Anti-platelet and Anti-coagulation Therapy (2013) (12)
Vitamin and supplement use among old order amish: sex-specific prevalence and associations with use. (2015) (12)
Extent and Distribution of Linkage Disequilibrium in the Old Order Amish (2009) (12)
Rare genetic coding variants associated with human longevity and protection against age-related diseases (2021) (12)
Genome-wide association analysis of common genetic variants of resistant hypertension (2018) (12)
The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin. (2015) (12)
Analysis of the bereavement effect after the death of a spouse in the Amish: a population-based retrospective cohort study (2014) (12)
Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation (2019) (12)
Identifying clinically relevant sources of variability: The clopidogrel challenge (2017) (12)
A population-specific reference panel empowers genetic studies of Anabaptist populations (2017) (12)
From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases (2016) (11)
Familial aggregation of tobacco use behaviors among Amish men. (2014) (11)
Genetics of Diabetes (2004) (11)
Molecular Scanning of β-3-Adrenergic Receptor Gene in Total Congenital Lipoatrophic Diabetes Mellitus (1997) (11)
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (11)
Autosome-wide linkage analysis of hip structural phenotypes in the Old Order Amish. (2008) (11)
GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms (2020) (11)
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease (2022) (11)
Hepatic lipase genotype, diabetes risk, and implications for preventative medicine. (2004) (10)
1168 IL28B GENETIC VARIATION ASSOCIATED WITH EARLY VIRAL KINETICS AND SVR IN HCV GENOTYPE 1 THE VIRAHEP-C STUDY (2010) (10)
FABP 2 Ala 54 Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women 1 – 3 (2006) (10)
A catalog of associations between rare coding variants and COVID-19 outcomes (2020) (10)
Genomics: Variations in blood lipids (2010) (10)
Increased usual physical activity is associated with a blunting of the triglyceride response to a high-fat meal. (2019) (10)
Polyherbal dietary supplementation for prediabetic adults: study protocol for a randomized controlled trial (2019) (10)
Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for PAPSS2 as a Longevity Gene. (2016) (10)
Characterization of exome variants and their metabolic impact in 6,716 American Indians from Southwest US (2020) (10)
Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response (2014) (10)
Common and rare variant associations with clonal haematopoiesis phenotypes (2022) (10)
Establishing the role of PLVAP in protein-losing enteropathy: a homozygous missense variant leads to an attenuated phenotype (2018) (10)
The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations (2016) (10)
Xenopus laevis oocytes, eggs and tadpoles contain immunoactive insulin. (1994) (9)
Genetic Variation in PEAR1, Cardiovascular Outcomes and Effects of Aspirin in a Healthy Elderly Population (2020) (9)
Exome sequencing of 628,388 individuals identifies common and rare variant associations with clonal hematopoiesis phenotypes (2022) (9)
Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. (2007) (9)
Homozygosity for CHEK2 p.Gly167Arg leads to a unique cancer syndrome with multiple complex chromosomal translocations in peripheral blood karyotype (2019) (9)
Assignment of the human pancreatic regenerating (REG) gene to chromosome 2p12. (1994) (9)
Paediatric systemic lupus erythematosus as a manifestation of constitutional mismatch repair deficiency (2019) (9)
Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (9)
BMI in the Old Order Amish. (2004) (8)
The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos. (1997) (8)
Analysis of the peroxisome proliferator activated receptor gamma (PPARgamma) gene in HAIRAN syndrome with obesity. (2000) (8)
Using Workflow Modeling to Identify Areas to Improve Genetic Test Processes in the University of Maryland Translational Pharmacogenomics Project (2015) (8)
The Association between Factor XI Deficiency and the Risk of Bleeding, Cardiovascular, and Venous Thromboembolic Events (2021) (8)
Trp64Arg variant of the beta3-adrenoceptor and insulin resistance in obese postmenopausal women. (1998) (8)
USE OF GENOME SCANS TO IDENTIFY SUSCEPTIBILITY GENES FOR TYPE 2 DIABETES (2001) (8)
Cardiovascular risks impact human brain N-acetylaspartate in regionally specific patterns (2019) (8)
Prevalence, control, and treatment of diabetes, hypertension, and high cholesterol in the Amish (2020) (8)
Genetic Variants of PEAR1 are Associated with Platelet Function and Antiplatelet Drug Efficacy: A Systematic Review and Meta-Analysis. (2018) (8)
Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip (2014) (7)
An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels (2018) (7)
Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation (2016) (7)
Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians. (2019) (7)
Effect of Serum Zinc and Copper Levels on Insulin Secretion, Insulin Resistance and Pancreatic β cell Dysfunction in US Adults: Findings from the National Health and Nutrition Examination Survey (NHANES) 2011-2012. (2020) (7)
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2016) (7)
Lipid Metabolism, Abdominal Adiposity and Cerebral Health in the Amish (2017) (7)
The IGNITE network: a model for genomic medicine implementation and research (2015) (7)
Beta 3-adrenoceptor gene variant in obesity and insulin resistance. (1996) (7)
Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel. (2013) (7)
Common genetic variants identify targets for COVID-19 and individuals at 1 high risk of severe disease 2 (2021) (7)
Clopidogrel pharmacogenetics: Beyond candidate genes and genome‐wide association studies (2017) (7)
Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
Molecular scanning of the beta‐3‐adrenergic receptor gene in Pima Indians and Caucasians (1999) (6)
TCF 7 L 2 Polymorphism , Weight Loss and Proinsulin : Insulin Ratio in the Diabetes Prevention Program (2011) (6)
KCNQ1 and Long QT Syndrome in 1/45 Amish (2020) (6)
Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen (2021) (6)
Increased Gut Microbiome Diversity Following a High Fiber Mediterranean Style Diet (2013) (6)
Transgenic animals. (1996) (6)
A case of congenital generalized lipodystrophy: metabolic effects of four dietary regimens. Lack of association of CGL with polymorphism in the lamin A/C Gene (2001) (6)
Profiling copy number variation and disease associations from 50,726 DiscovEHR Study exomes (2017) (6)
When phenotype does not match genotype: importance of “real-time” refining of phenotypic information for exome data interpretation (2020) (6)
Association of the Vitamin D Metabolism Gene CYP 24 A 1 With Coronary Artery Calcification (2010) (5)
A common variant in fibroblast growth factor binding protein 1 (FGFBP1) is associated with bone mineral density and influences gene expression in vitro. (2010) (5)
Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen (2019) (5)
THE INFLUENCE OF CYTOCHROME P450 2C19*2 AND*17 GENOTYPE, DIPLOTYPE AND METABOLIZER STATUS ON PLATELET REACTIVITY IN PATIENTS ON MAINTENANCE CLOPIDOGREL THERAPY (2010) (5)
Epilepsy and electroencephalogram evolution in YWHAG gene mutation: A new phenotype and review of the literature (2021) (5)
The mechanism of interaction of dislocations with point defects in ionic crystals (2002) (5)
No effect of Trp64Arg beta3-adrenoceptor polymorphism on the plasma leptin concentration in Pima Indians. (1998) (5)
RNA Template-Specific Polymerase Chain Reaction (RS-PCR) : A Modification of RNA-PCR that Dramatically Reduces the Frequency of False Positives. (1993) (5)
Clonal hematopoiesis is driven by aberrant activation of TCL1A (2021) (5)
The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience (2022) (5)
Sunday, 26 August 2012 (2012) (5)
Serum alanine aminotransferase is correlated with hematocrit in healthy human subjects (2012) (5)
Heterozygosity for a Pathogenic Variant in SLC12A3 That Causes Autosomal Recessive Gitelman Syndrome Is Associated with Lower Serum Potassium. (2021) (4)
The free energy of vacancy pairs (1978) (4)
An Amish founder population reveals rare-population genetic determinants of the human lipidome (2022) (4)
Exome sequencing and characterization of 49,960 individuals in the UK Biobank (2020) (4)
Model for Integration of Monogenic Diabetes Diagnosis Into Routine Care: The Personalized Diabetes Medicine Program. (2022) (4)
Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes (2022) (4)
Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals (2021) (4)
CYP 2 C 19 Metabolizer Status and Clopidogrel Ef fi cacy in the Secondary Prevention of Small Subcortical Strokes ( SPS 3 ) Study (2015) (4)
Preparation of RNA from lyophilized tissue: a stable and reliable method for long-term storage. (1994) (4)
Molecular scanning of beta-3-adrenergic receptor gene in total congenital lipoatrophic diabetes mellitus. (1997) (4)
Self-Reported Sleep Duration and Pattern in Old Order Amish and Non-Amish Adults. (2019) (4)
Rapid synthesis of standards for allele-specific oligonucleotide hybridization. (1994) (4)
Exome Sequencing of 21 Bardet‐Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians (2021) (3)
Multiple dimensions of stress vs. genetic effects on depression (2021) (3)
Supplementary Material 6 (2014) (3)
Recovery of plasmid DNA from nonviable bacterial colonies and cultures. (1992) (3)
Supplementary Material 3 (2015) (3)
Heritability of plasma neopterin levels in the Old Order Amish (2017) (3)
The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient. (2009) (3)
Exome sequencing identifies a nonsense variant in DAO associated with reduced energy expenditure in American Indians. (2020) (3)
Supplementary Material 7 (2014) (3)
Thrombotic Risk Determined by STAB 2 Variants in a Population-Based Cohort Study. (2021) (3)
Biallelic truncating variants in the muscular A‐type lamin‐interacting protein (MLIP) gene cause myopathy with hyperCKemia (2021) (3)
CYP2C19 and Clopidogrel Response: More Than Validation in the Real World (2012) (3)
Adiponectin levels and genotype (2008) (3)
Supplementary Material 5 (2014) (3)
Genetic Factors in Exceptional Longevity—Reply (2004) (3)
Body Image and Life Satisfaction in Amish, Catholic, and Non-Religious Women (2018) (3)
The role of phenotype-based search approaches using public online databases in diagnostics of Mendelian disorders (2021) (3)
The diagnostic efficacy of exome data analysis using fixed neurodevelopmental gene lists: Implications for prenatal setting (2021) (3)
The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS) (2022) (3)
Genome-wide association study of kidney function decline in individuals of European descent: the CKDGen Consortium. (2015) (3)
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program (2021) (3)
Similar burden of pathogenic coding variants in exceptionally long‐lived individuals and individuals without exceptional longevity (2020) (3)
Role of a Proline Insertion in the Insulin Promoter Factor 1 (IPF1) Gene in African Americans With Type 2 Diabetes (2006) (3)
Calcified Granulomatous Disease: Occupational Associations and Lack of Familial Aggregation (2014) (2)
The two nonallelic Xenopus insulin genes are expressed coordinately in the adult pancreas. (1994) (2)
Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish. (2005) (2)
Clinical and genetic validity of quantitative bipolarity (2019) (2)
Two intronic cis‐acting variants in both alleles of the POLR3A gene cause progressive spastic ataxia with hypodontia (2021) (2)
Abstract 16563: Genetic and Pharmacological Inactivation of ANGPTL3 is Associated With Reduced Atherosclerotic Cardiovascular Disease (2016) (2)
Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence (2020) (2)
Rapid (ligase-free) subcloning of PCR products. (1997) (2)
The prevalence of prenatal sonographic findings in postnatal diagnostic exome sequencing performed for neurocognitive phenotypes: A cohort study (2022) (2)
Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans (2022) (2)
914. Toxoplasma Gondii Serointensity and Seropositivity and Their Heritability and Household-Related Associations in the Old Order Amish (2017) (2)
Mapping Genes in Isolated Populations: Lessons from the Old Order Amish (2015) (2)
Insulin, but Not Insulin‐like Growth Factor‐I, Is Expressed during Early Nervous System Development in Prepancreatic Xenopus Embryos (1993) (2)
Genetic versus stress and mood determinants of sleep in the Amish (2021) (2)
Self-Reported Sleep Duration and Pattern in Old Order Amish and Non-Amish Adults. (2019) (2)
N-cyclo-[Leu5]enkephalin: a rational approach for the synthesis of conformationally restricted cyclic pentapeptides. (1985) (2)
297. Dichgans M, Malik R, Konig IR, Rosand J, Clarke R, Gretarsdottir S, . . . , Schunkert H (2014). Shared genetic susceptibility to ischemic stroke and coronary artery disease: a (2014) (2)
Genome-wide association scans identify novel loci that influence lipid levels and risk of coronary artery disease (2007) (2)
Genetics of the metabolic complications of obesity. (2010) (2)
Preparation and properties of poly(2,2-dialkyltrimethylene sulphones) (1981) (2)
Does bariatric surgery reduce obesity-related comorbidities? (2005) (1)
UGT1A1 genetic variants are associated with increases in bilirubin levels in rheumatoid arthritis patients treated with sarilumab (2017) (1)
Cognitive profiles and heritability estimates in the Old Order Amish (2016) (1)
Supplementary Material 9 (2013) (1)
Putative association signals identified through high-density LD mapping of the replicated T2D linkage region on chromosome 1q are not confirmed in large-scale follow-up studies (2008) (1)
Genome-wide physical activity interactions in adiposity (2017) (1)
Clinical case study meets population cohort: Identification of a BRCA1 pathogenic founder variant in Orcadians (2022) (1)
Discovery and Refinement Supplementary (2015) (1)
Carbohydrate Metabolism: Diabetes Mellitus, Genomic Aberrations (2004) (1)
NFAT 5 and SLC 4 A 10 Loci Associate with Plasma Osmolality (2017) (1)
The burden of pathogenic variants in clinically actionable genes in a founder population (2021) (1)
Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians (2022) (1)
Supplementary Material 4 (2015) (1)
Rapid (ligase-free) subcloning of polymerase chain reaction products. (1993) (1)
556. Adiponectin Gene Polymorphism and Seasonality in the Old Order Amish (2017) (1)
Depression, stress and regional cerebral blood flow (2023) (1)
Genome-wide survey of parent-of-origin specific associations across clinical traits derived from electronic health records (2020) (1)
Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population (2022) (1)
High-density association mapping and comprehensive tagging of the type 2 diabetes linkage region on chromosome 1q in 4 European populations (2007) (1)
Pharmacogenomic Study of Statin-Associated Muscle Symptoms in the ODYSSEY OUTCOMES Trial (2022) (1)
Clinical characterization of familial hypercholesterolemia due to an amish founder mutation in Apolipoprotein B (2022) (1)
Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease (2021) (1)
Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis (2017) (1)
Evaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish (2018) (1)
Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
Supplementary Material 15 (2013) (1)
OBESITY AND DIABETES : RESEARCH POINTS TO GENETIC CONNECTION (1997) (1)
203. Environmental Risk Factors for Toxoplasma Gondii Seropositivity in the Old Order Amish (2017) (1)
Genetics of Type 2 Diabetes: From Candidate Genes to Genome-Wide Association Analysis (2010) (1)
Historical Overview of Gene Discovery Methodologies in Type 2 Diabetes (2016) (1)
A novel TUFM homozygous variant in a child with mitochondrial cardiomyopathy expands the phenotype of combined oxidative phosphorylation deficiency 4 (2019) (1)
Variants in ANGPTL4 and the Risk of Coronary Artery Disease. (2016) (1)
Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (1)
A novel mutation in MYCN gene causing congenital absence of the flexor pollicis longus tendon as an unusual presentation of Feingold syndrome 1. (2020) (1)
Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
A missense variant Arg611Cys in LIPE which encodes hormone sensitive lipase decreases lipolysis and increases risk of type 2 diabetes in American Indians (2021) (1)
Cerebral blood flow and cardiovascular risk effects on resting brain regional homogeneity (2022) (1)
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2021) (1)
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma (2022) (1)
Autoantibodies in Type 1 and Type 2 diabetes in the Old Order Amish of Lancaster County, Pennsylvania (2003) (1)
Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations (2018) (0)
Abstract 11242: Clopidogrel Improves Endothelial Function in Healthy Individuals With Heightened Platelet Aggregation (2016) (0)
Genome-wide association analysis of common genetic variants of resistant hypertension (2018) (0)
Comprehensive Genetic Analysis of Druze Provides Insights into Carrier Screening (2023) (0)
Impact of parental relatedness on reproductive outcomes among the Old Order Amish of Lancaster County (2022) (0)
KCNJ11 Mutation in One Family is Associated with Adult-Onset Rather than Neonatal-Onset Diabetes Mellitus (2018) (0)
University of Groningen A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function Porcu, (2013) (0)
Abstract P392: Exome Sequencing From Extreme Responders to Aspirin Identifies a Novel Variant Associated With Platelet Aggregation (2015) (0)
Administration: Real Life Is Complicated Responding to the Clopidogrel Warning by the US Food and Drug (2011) (0)
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis (2020) (0)
Old Order Amish Have Higher Than Expected Severity of Coronary Artery Calcification (2005) (0)
Decision letter: Whole-genome sequencing analysis of semi-supercentenarians (2020) (0)
When phenotype does not match genotype: importance of “real-time” refining of phenotypic information for exome data interpretation (2020) (0)
The Old Order Amish: A unique model to study ageing (2000) (0)
Linkage disequilibrium mapping of the type 2 diabetes susceptibility variants on chromosome Iq in European populations (2005) (0)
Parkinson’s Disease-Related Motor and Nonmotor Symptoms in the Lancaster Amish (2020) (0)
Abstract 3753: Is Isolated Low HDL-C An Atherogenic Phenotype? The Amish Family Calcification Study (2007) (0)
Regionally enriched rare deleterious exonic variants in the UK and Ireland (2022) (0)
Genetic Determinants of Arterial Thrombosis (2009) (0)
O B S E Rvat I O N S Table 1—characteristics of Respondents Aged 45 Years Reporting Screening for Diabetes in Montana in 1998 (0)
POSTER SESSION II (2015) (0)
Trp64Arg Beta-3-Adrenergic Receptor A Common Genetic Variant that Influences Features of the Insulin Resistance Syndrome (Syndrome X) and the Age of Onset of Noninsulin Dependent Diabetes Mellitus (1996) (0)
Hydroxysteroid 17-beta dehydrogenase 13 (hsd17b13) variants and uses thereof (2018) (0)
Functional characterization of blood pressure‐associated common variants in STK39 (2009) (0)
Obesity and diabetes: research points to genetic connection. Interview by Mark E. Weksler. (1997) (0)
Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences. (2021) (0)
Functional modeling of human lysosomal acid alpha-glucosidase variants (2022) (0)
Front & Back Matter (2013) (0)
Abstract 32: Analysis of Serum Clopidogrel Active Metabolite Concentration Identifies Novel Genetic Variants Associated With Clopidogrel Pharmacokinetics (2016) (0)
Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish (2023) (0)
Large-scale follow-up study does not confirm putative association signals in the NOS1AP and PKLR gene regions on chromosome 1q with type 2 diabetes (2008) (0)
Evidence of Neurovascular Water Exchange and Endothelial Vascular Dysfunction in Schizophrenia: An Exploratory Study. (2023) (0)
78. NEURODEVELOPMENTAL CONSEQUENCES OF RARE SETD1A MISSENSE VARIANTS ASSOCIATED WITH RISK FOR BIPOLAR DISORDER (2022) (0)
Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response (2014) (0)
Xenopus Zuevis Contains Two Nonallelic Preproinsulin Genes cDNA (2001) (0)
Genome-wide association and functional follow-up reveals new loci for kidney function | NOVA. The University of Newcastle's Digital Repository (2012) (0)
The β3-Adrenergic Receptor and Susceptibility to Obesity, the Insulin Resistance Syndrome, and Noninsulin-Dependent Diabetes Mellitus (1998) (0)
VARIANTS OF PCSK 9 ARE ASSOCIATED WITH TRIGLYCERIDE LEVELS IN THE OLD ORDER AMISH Student Researcher : (2007) (0)
Lack of Cardiovascular Disease Among Old Order Amish With Familial Defective Apolipoprotein B—Reply (2011) (0)
1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis (2020) (0)
B4galt1 variants and uses thereof (2018) (0)
S60GENOME SEQUENCING IN A FOUNDER POPULATION IDENTIFIES POPULATION-ENRICHED PROTEIN-CODING VARIANTS IN NEURODEVELOPMENTAL GENES ASSOCIATED WITH RISK FOR MOOD DISORDERS (2019) (0)
Pharmacogenomics: the low-hanging fruit in the personalized medicine tree (2022) (0)
Functional Variants in MBL2 are Associated with Type 2 diabetes and Pre- diabetic Traits in Pima Indians and the Old Order Amish Running Title: MBL2 and Type 2 diabetes (2010) (0)
Tobacco Use And Airway Obstruction In The Old Order Amish (2012) (0)
Carrying one or two reduced-function CYP2C19 alleles is associated with an increased risk of major adverse cardiovascular events in people undergoing percutaneous coronary intervention and treated with clopidogrel (2011) (0)
Genome Scans of Type 2 Diabetes Mellitus (2003) (0)
A population-specific reference panel empowers genetic studies of Anabaptist populations (2017) (0)
Abstract 15465: Precision Medicine Approach to Resistant Hypertension: Genetic Markers of Resistant Hypertension Through a Genome-wide Association Study (GWAS) in the Secondary Prevention of Subcortical Strokes (SPS3) (2015) (0)
Impact of genetic relatedness of parents on reproductive outcomes (2021) (0)
Genome-wide survey of parent-of-origin-specific associations across clinical traits derived from electronic health records (2021) (0)
SAT0179 The ASP358ALA variant in the IL6R gene is significantly associated with differences in soluble IL-6R protein levels but not with differences in sarilumab response in rheumatoid arthritis (RA) patients (2017) (0)
American Society for Clinical Pharmacology and Therapeutics (1975) (0)
Rare coding variants in CHRNB2 reduce the likelihood of smoking (2022) (0)
COLLECTIVE EFFECTS OF ADRENERGIC RECEPTOR (AR) POLYMORPHISMS ARE ASSOCIATED WITH BODY FAT RESPONSE TO TRAINING (2003) (0)
Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings (2021) (0)
238-LB: Prevalence of GCK-MODY in 92,412 Exomes from an Unselected Clinical Population (2019) (0)
2116-P: A Pipeline to Explore Rare Variation Which Can Contribute to Extreme Obesity in American Indians (2019) (0)
Replicated association between type 2 diabetes and variants in CAPON revealed by high density linkage disequilibrium mapping on chromosome 1q (2006) (0)
Vitamin and Supplement Use in the Old Order Amish: Gender-specific prevalence and associations with use (2015) (0)
271-OR: Whole-Exome Sequence Identifies Potentially Functional Rare Variants in Bardet-Biedl Syndrome (BBS) Genes that Associate with Obesity in American Indians (2019) (0)
Running Title : Candidate genes in the Diabetes Prevention Program (2010) (0)
Genetic Predictors ofWeight Loss and Weight Regain After Intensive Lifestyle Modi fi cation , Metformin Treatment , or Standard Care in the Diabetes Prevention Program (2011) (0)
Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations (2018) (0)
Determination of the genomic structures of two nonallelic preproinsulin genes in Xenopus laevis using the polymerase chain reaction. (1995) (0)
Epigenetic Signature of Impaired Fasting Glucose in the Old Order Amish. (2017) (0)
The C297T Polymorphism In Uncoupling Protein 3 Does Not Associate With Traits Related To Obesity (1998) (0)
FABP2 Genotype and Exercise Training as Determinants of Glucoregulatory Function and Postprandial Lipemia (2004) (0)
503. Neurodevelopmental Consequences of Rare SETD1A Missense Variants Associated With Risk for Bipolar Disorder (2023) (0)
GWAS results in the Diabetes Prevention Program EXTENSION OF TYPE 2 DIABETES GENOME-WIDE ASSOCIATION SCAN RESULTS IN THE DIABETES PREVENTION PROGRAM (2008) (0)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure (2020) (0)
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes (2023) (0)
Abstract 15853: Identification of Several Novel Loci for Coagulation and Fibrinolysis (2017) (0)
Pharmacogenetics of SGLT2 Inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker (2023) (0)
EFFECTS OF PPAR-GAMMA GENOTYPE ON ENDURANCE TRAINING-INDUCED CHANGES IN INSULIN RESPONSE TO ORAL GLUCOSE (2003) (0)
Contents Vol. 9, 2016 (2017) (0)
Supplementary Material for: The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations (2016) (0)
Nitrate From Drinking Water and Prevalence of Abnormal Thyroid Conditions Among the Old Order Amish in Pennsylvania (2011) (0)
Contents Vol. 64, 2007 (2007) (0)
intensities in postmenopausal women Cardiovascular hemodynamics with increasing exercise (2015) (0)
Large-scale association studies to identify diabetes-susceptibility loci on chromosome 1q: The importance of stringent quality control (2006) (0)
Exome sequencing reveals aggregates of rare variants in glycosyltransferase and other genes influencing immunoglobulin G and transferrin glycosylation (2022) (0)
Evaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish (2018) (0)
Abstract 14753: Loss of Function ABCC8 Mutations Are Associated With Pulmonary Arterial Hypertension (2017) (0)
Exome-wide association studies in general and long-lived populations identify genetic variants related to human age (2020) (0)
Genome-wide physical activity interactions in adiposity A meta-analysis of 200,452 adults Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (0)
Genome-wide association study reveals loci with sex-specific effects on plasma bile acids (2022) (0)
Genetic factors in exceptional longevity. Authors' reply (2004) (0)
Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581] (2021) (0)
294. Positive Association between Toxoplasma Gondii IgG Serointensity and Depression in the Old Order Amish (2017) (0)
Abstract 37: Secondary Stroke Prevention With Aspirin and Clopidogrel in CYP2C19 *17 Carriers Increases Risk of Major Non-CNS Bleeding (2019) (0)
Parkinson’s disease-related motor and non-motor symptoms are not more prevalent in the Lancaster Amish (2020) (0)
Electron emission and luminescence due to plastic deformation of ionic crystals (1998) (0)
Abstract 1438: Myocardial Infarction Associated SNPs on Chromosome 9p21.3 are Associated with Coronary Artery Calcification but Not Carotid Intimal Medial Thickness in the Amish (2008) (0)
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis (2023) (0)
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver diseases that have distinct effects on metabolic traits Speliotes (0)
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes (2023) (0)
Academic and industry perspectives on pharmacogenomics: drug optimization (2019) (0)
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes (2018) (0)
Chronotype is associated with seasonal weight and sleep duration changes in the old order Amish (2015) (0)
Abstract 15641: Genome-Wide Association Study and Meta-Analysis of Aspirin Responsiveness in Individuals of European Descent (2011) (0)
Follow-Up in Myocardial Infarction Genome-Wide Association Study for Coronary Artery Calcification With (2011) (0)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2020) (0)
Variation in the retinoid X receptor gamma gene is associated with type 2 diabetes in sample sets displaying linkage to chromosome 1q (2006) (0)
A Unique Presentation of Infantile-Onset Colitis and Eosinophilic Disease without Recurrent Infections Resulting from a Novel Homozygous CARMIL2 Variant (2019) (0)
Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness (2023) (0)
The Thrifty Microbiome: The Role of the Gut Microbiota in Obesity in the Amish (2010) (0)
Abstract P365: A Variant Impacting Beta-Oxidation of Medium-Chain Fatty Acids is Associated With Response to Triglyceride Challenge and Lipoprotein Subfractions (2015) (0)

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