Albert Claude
Cell biologist
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Biology
Albert Claude's Degrees
- Doctorate Medicine Université libre de Bruxelles
Why Is Albert Claude Influential?
(Suggest an Edit or Addition)According to Wikipedia, Albert Claude was a Belgian-American cell biologist and medical doctor who shared the Nobel Prize in Physiology or Medicine in 1974 with Christian de Duve and George Emil Palade. His elementary education started in a comprehensive primary school at Longlier, his birthplace. He served in the British Intelligence Service during the First World War, and got imprisoned in concentration camps twice. In recognition of his service, he was granted enrolment at the University of Liège in Belgium to study medicine without any formal education required for the course. He earned his Doctor of Medicine degree in 1928. Devoted to medical research, he initially joined German institutes in Berlin. In 1929 he found an opportunity to join the Rockefeller Institute in New York. At Rockefeller University he made his most groundbreaking achievements in cell biology. In 1930 he developed the technique of cell fractionation, by which he discovered the agent of the Rous sarcoma, components of cell organelles such as mitochondrion, chloroplast, endoplasmic reticulum, Golgi apparatus, ribosome and lysosome. He was the first to employ the electron microscope in the field of biology. In 1945 he published the first detailed structure of cell. His collective works established the complex functional and structural properties of cells.
Albert Claude's Published Works
Published Works
- A STUDY OF TISSUE CULTURE CELLS BY ELECTRON MICROSCOPY (1945) (467)
- FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION (1946) (255)
- Fractionation of mammalian liver cells by differential centrifugation; problems, methods, and preparation of extract. (1946) (246)
- GROWTH AND DIFFERENTIATION OF CYTOPLASMIC MEMBRANES IN THE COURSE OF LIPOPROTEIN GRANULE SYNTHESIS IN THE HEPATIC CELL I. Elaboration of Elements of the Golgi Complex (1970) (225)
- THE CONSTITUTION OF PROTOPLASM. (1943) (159)
- The distribution of cytochrome oxidase and succinoxidase in the cytoplasm of the mammalian liver cell. (1946) (159)
- AN ELECTRON MICROSCOPE STUDY OF ISOLATED MITOCHONDRIA : METHOD AND PRELIMINARY RESULTS (1945) (111)
- Particulate components of cytoplasm (1941) (109)
- The distribution of cytochrome c and succinoxidase activity in rat liver fractions. (1948) (107)
- PARTICULATE COMPONENTS OF NORMAL AND TUMOR CELLS. (1940) (107)
- The nature of the Golgi apparatus. I. Parallelism between intercellular myelin figures and Golgi apparatus in somatic cells (1949) (104)
- Electron Microscope Study of Chicken Tumor Cells (1947) (95)
- Studies on cells: Morphology, chemical constitution, and distribution of biochemical functions (1948) (84)
- THE CONSTITUTION OF MITOCHONDRIA AND MICROSOMES, AND THE DISTRIBUTION OF NUCLEIC ACID IN THE CYTOPLASM OF A LEUKEMIC CELL (1944) (78)
- The nature of the Golgi apparatus. II. Identification of the Golgi apparatus with a complex of myelin figures (1949) (73)
- A Fraction from Normal Chick Embryo Similar to the Tumor Producing Fraction of Chicken Tumor I (1938) (68)
- ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS (1943) (60)
- MITOCHONDRIA IN ANAEROBICALLY-GROWN, LIPID-LIMITED BREWER'S YEAST (1969) (58)
- THE PREPARATION OF SECTIONS OF GUINEA PIG LIVER FOR ELECTRON MICROSCOPY (1946) (58)
- CONCENTRATION AND PURIFICATION OF CHICKEN TUMOR I AGENT. (1938) (55)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1935) (51)
- CHEMICAL COMPOSITION OF THE TUMOR-PRODUCING FRACTION OF CHICKEN TUMOR I. (1939) (51)
- Distribution of nucleic acids in the cell and the morphological constitution of cytoplasm (1943) (44)
- The coming of age of the cell. (1975) (38)
- Proteins, Lipids, and Nucleic Acids in, Cell Structures and Functions (1949) (36)
- STUDIES ON CELL MORPHOLOGY AND FUNCTIONS: METHODS AND RESULTS (1950) (34)
- SPREADING PROPERTIES OF LEECH EXTRACTS AND THE FORMATION OF LYMPH (1937) (30)
- TRANSMISSIBLE TUMORS OF THE FOWL (1933) (30)
- AN ELECTRON MICROSCOPE STUDY OF SALIVARY GLAND CHROMOSOMES BY THE REPLICA METHOD (1949) (29)
- A spontaneous, transplantable renal carcinoma of the mouse. Electron microscope study of the cells and of an associated virus-like particle. (1962) (28)
- Problems of fixation for electron microscopy. Results of fixation with osmium tetroxide in acid and alkaline media. (1961) (27)
- Electron microscope observations on virus particles associated with a transplantable renal adenocarcinoma in BALB-cf-Cd mice. (1969) (26)
- The Metabolism of Chicken Tumors (1941) (26)
- “Spreading” Properties and Mucolytic Activity of Leech Extracts (1940) (26)
- GROWTH AND DIFFERENTIATION OF CYTOPLASMIC MEMBRANES IN THE COURSE OF LIPOPROTEIN GRANULE SYNTHESIS IN THE HEPATIC CELL (1970) (23)
- Microsomes, endoplasmic reticulum and interactions of cytoplasmic membranes (1969) (21)
- PREPARATION OF AN ACTIVE AGENT FROM INACTIVE TUMOR EXTRACTS. (1937) (21)
- AN ELECTRON MICROSCOPE STUDY OF ISOLATED MITOCHONDRIA (1945) (20)
- CHEMICAL PROPERTIES OF THE PURIFIED SPREADING FACTOR FROM TESTICLE (1937) (20)
- Quantitative evaluation of polysomes and ribosomes by density gradient centrifugation and electron microscopy. (1971) (19)
- ON THE EXISTENCE OF A FACTOR INCREASING TISSUE PERMEABILITY IN ORGANS OTHER THAN TESTICLE (1934) (19)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1937) (18)
- SECTION OF BIOLOGY: Mechanical Separation of the Morphological Constituents of the Cell (1942) (16)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1932) (16)
- OBSERVATIONS CONCERNING THE CAUSATIVE AGENT OF A CHICKEN TUMOR. (1931) (15)
- ELECTRON MICROSCOPE STUDIES OF CELLS BY THE METHOD OF REPLICAS (1949) (12)
- [Endemic renal adenocarcinoma in a pure mouse strain; its effect on growth]. (1958) (11)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1935) (11)
- Cell morphology and the organization of enzymatic systems in cytoplasm (1954) (11)
- Fractionation of Chicken Tumor Extracts by High Speed Centrifugation (1937) (10)
- FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION (1946) (10)
- Structure in relation to cellular function (1950) (10)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1932) (10)
- SPREADING PROPERTY OF AZOPROTEINS IN THE DERMIS (1935) (8)
- PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR (1932) (8)
- Fixation of nuclear structures by unbuffered solutions of osmium tetroxide in slightly acid distilled water (1962) (8)
- THE ENHANCING EFFECT OF AZOPROTEINS ON THE LESIONS PRODUCED BY VACCINE VIRUS, THE SHOPE FIBROMA VIRUS, AND THE AGENT TRANSMITTING CHICKEN TUMOR I (1939) (7)
- Further Experiments on the Effect of Testicle Extract on the Agent of Chicken Tumor I (1934) (7)
- Interrelation of cytoplasmic membranes in mammalian liver cells: Endoplasmic reticulum and Golgi complex (1968) (6)
- A GROUP OF CHEMICALS ACTIVE IN INCREASING TISSUE PERMEABILITY AND ENHANCING CERTAIN INFECTIOUS PROCESSES. (1933) (6)
- [Comparative study by electron microscopy of cytochemical reactions of digitonin with cholesterol and other lipids in adrenal cortex cells]. (1970) (6)
- Liver Degeneration and Cirrhosis Produced by 1: 2: 5: 6-Dibenzanthracene (1937) (4)
- Distribution of Enzymatic Activities in Fractions of Mammalian Liver (1945) (4)
- Preservation of lipids and ultrastructure in cells of the adrenal cortex of the rat (1968) (3)
- [Morphology and organization of nuclear constituents in a case of renal carcinoma in the mouse]. (1961) (2)
- Properties of the Inhibitor Associated with the Active Agent of Chicken Tumor I (1939) (2)
- An active cell factor inhibiting body growth in mice: Its origin and mode of action. Control of cellular growth in adult organisms (1967) (2)
- Chemical constitution of chicken tumor extracts (1934) (2)
- [Demonstration by electron microscopy, of a fibrillary apparatus in the cytoplasm and nucleus of various cells]. (1961) (2)
- Study of lipids by electron diffraction and electron microscopy in tissue and in vitro (1970) (1)
- FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION (1946) (1)
- Electron microscopy of animal cells. (1946) (1)
- Origin of the membrane structures of the Golgi apparatus, and their differentiation during synthesis, transport and disposal of lipoprotein granules in liver cells (1970) (1)
- — Albert , Microsomal Particles and Protein Synthesis [ 8 ] (0)
- Observations Concerning the Causative Agent of a Chicken Tumor (1931) (0)
- [Correlation between the morphology and lipid content of the guinea pig, rat and bovine adrenal cortices]. (1973) (0)
- Origin and differentiation of membrane structure of the Golgi apparatus in the hepatic cell (1970) (0)
- Renal adenocarcinoma, endemic in an inbred strain of mice, its effect on body growth, and premiminary results of electron microscopy (1960) (0)
- Microscopy, differential centrifugation and biochemistry in the exploration of the cell (1964) (0)
- The preparation of sections of guinea pig liver for electron microscopy. (1946) (0)
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