Aldons Jake Lusis

Aldons Jake Lusis's AcademicInfluence.com Rankings

Aldons Jake Lusis

Engineering

#1583

World Rank

#2306

Historical Rank

Biomedical Engineering

#31

World Rank

#31

Historical Rank

Applied Physics

#134

World Rank

#142

Historical Rank

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Engineering

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Aldons Jake Lusis's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease (2011) (4016)
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis (2013) (3174)
Atherosclerosis : Vascular biology (2000) (2710)
Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. (1995) (1852)
Genetics of gene expression surveyed in maize, mouse and man (2003) (1549)
Integrative approaches for large-scale transcriptome-wide association studies (2015) (1235)
Multi-omics approaches to disease (2017) (1156)
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk (2016) (1136)
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis (1998) (1098)
An integrative genomics approach to infer causal associations between gene expression and disease (2005) (1069)
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. (1998) (1046)
Mapping the Genetic Architecture of Gene Expression in Human Liver (2008) (1040)
Synthetic LXR ligand inhibits the development of atherosclerosis in mice (2002) (946)
The Collaborative Cross, a community resource for the genetic analysis of complex traits (2004) (921)
Variations in DNA elucidate molecular networks that cause disease (2008) (901)
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis (2015) (878)
Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins (1990) (804)
Tissue-specific expression and regulation of sexually dimorphic genes in mice. (2006) (800)
The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. (1996) (750)
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. (2013) (740)
Myeloperoxidase, a Leukocyte-Derived Vascular NO Oxidase (2002) (667)
Thematic review series: The Pathogenesis of Atherosclerosis Published, JLR Papers in Press, April 1, 2004. DOI 10.1194/jlr.R400001-JLR200 The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL (2004) (666)
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. (2004) (637)
Comparative Analysis of Proteome and Transcriptome Variation in Mouse (2011) (564)
Ambient Particulate Pollutants in the Ultrafine Range Promote Early Atherosclerosis and Systemic Oxidative Stress (2008) (561)
Complete protein sequence and identification of structural domains of human apolipoprotein B (1986) (549)
Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. (2011) (522)
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. (2008) (522)
Systems genetics approaches to understand complex traits (2013) (520)
Molecular basis of the little mouse phenotype and Implications for cell type-specific growth (1993) (469)
Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight (2006) (462)
Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. (2013) (458)
Decreased Atherosclerotic Lesion Formation in Human Serum Paraoxonase Transgenic Mice (2002) (454)
Identification of macrophage liver X receptors as inhibitors of atherosclerosis (2002) (452)
Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB (2016) (449)
Sex differences and hormonal effects on gut microbiota composition in mice (2016) (448)
HDL and the inflammatory response induced by LDL-derived oxidized phospholipids. (2001) (447)
Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice (2002) (440)
Individual diet has sex-dependent effects on vertebrate gut microbiota (2014) (433)
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis* (2000) (414)
Human lipoprotein lipase complementary DNA sequence. (1987) (413)
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. (2014) (383)
A Tale of Two Controversies (2002) (378)
Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice. (1997) (369)
Human Paraoxonase-3 Is an HDL-Associated Enzyme With Biological Activity Similar to Paraoxonase-1 Protein but Is Not Regulated by Oxidized Lipids (2001) (367)
ACAT-2, A Second Mammalian Acyl-CoA:Cholesterol Acyltransferase (1998) (364)
Cloning of a Third Mammalian Na+-Ca2+ Exchanger, NCX3* (1996) (363)
Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II. (1993) (360)
Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation* (2014) (358)
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200189-JLR200 (2002) (354)
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1) (2004) (353)
CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis (2016) (351)
Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. (2019) (347)
The Unfolded Protein Response Is an Important Regulator of Inflammatory Genes in Endothelial Cells (2006) (345)
Weighted gene coexpression network analysis strategies applied to mouse weight (2007) (333)
Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. (2010) (333)
Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. (1997) (323)
Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. (2001) (321)
Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential (2018) (317)
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids (2006) (316)
Dosage compensation is less effective in birds than in mammals (2007) (316)
Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. (1997) (314)
Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in mice. (1993) (311)
A high-resolution association mapping panel for the dissection of complex traits in mice. (2010) (310)
Metabolic syndrome: from epidemiology to systems biology (2008) (308)
Increased atherosclerosis in myeloperoxidase-deficient mice. (2001) (306)
Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. (1987) (303)
The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance. (2015) (303)
Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice (2001) (297)
Cis-acting expression quantitative trait loci in mice. (2005) (292)
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds. (2000) (271)
Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model. (1996) (264)
Thioredoxin-Interacting Protein (2008) (264)
Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. (1994) (261)
Genetics of atherosclerosis. (2012) (260)
Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice. (1998) (259)
The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. (1987) (258)
Role of group II secretory phospholipase A2 in atherosclerosis: 1. Increased atherogenesis and altered lipoproteins in transgenic mice expressing group IIa phospholipase A2. (1999) (251)
Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis[S] (2015) (251)
Genetic and environmental control of host-gut microbiota interactions (2015) (250)
Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model (2018) (247)
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. (2002) (247)
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis (2001) (243)
CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade1 (2009) (242)
Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. (1994) (242)
Testosterone inhibits early atherogenesis by conversion to estradiol: Critical role of aromatase (2001) (241)
Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men (2012) (240)
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. (1997) (240)
A thematic review series: systems biology approaches to metabolic and cardiovascular disorders (2006) (237)
Ligand activation of LXRβ reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRα and apoE (2007) (237)
Identification of a zinc finger protein that binds to the sterol regulatory element. (1989) (235)
Inhibition of bone morphogenetic protein protects against atherosclerosis and vascular calcification (2010) (234)
The sequence of cDNA encoding lipoprotein lipase. A member of a lipase gene family. (1987) (226)
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. (2013) (222)
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (2005) (220)
Genetic factors affecting blood lipoproteins: the candidate gene approach. (1988) (220)
Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort (2017) (220)
Minimally modified low density lipoprotein is biologically active in vivo in mice. (1991) (217)
Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. (2009) (213)
An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits (2010) (213)
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition. (2019) (210)
Large-scale association analyses identify host factors influencing human gut microbiome composition (2020) (206)
Paraoxonase and coronary heart disease. (2002) (205)
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing. (2005) (205)
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration (2017) (204)
Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. (2000) (202)
Genetic Basis of Atherosclerosis: Part I: New Genes and Pathways (2004) (201)
Positional cloning of the combined hyperlipidemia gene Hyplip1 (2002) (198)
Genetic and Genomic Analysis of a Fat Mass Trait with Complex Inheritance Reveals Marked Sex Specificity (2006) (195)
Thioredoxin‐interacting protein deficiency induces Akt/Bcl‐xL signaling and pancreatic beta‐cell mass and protects against diabetes (2008) (190)
What Genes Can't Do (2003) (189)
Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. (1997) (189)
The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism. (1999) (187)
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease (2014) (187)
Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21. (1987) (183)
Identification of four chromosomal loci determining obesity in a multifactorial mouse model. (1995) (183)
Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids. (1999) (175)
Role of Phospholipid Oxidation Products in Atherosclerosis (2012) (175)
Heme Oxygenase-1 Expression in Macrophages Plays a Beneficial Role in Atherosclerosis (2007) (174)
Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV. (1997) (172)
The role of high-density lipoproteins in oxidation and inflammation. (2001) (171)
Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice. (1993) (170)
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. (2017) (167)
Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association. (2017) (166)
Genetic architecture of insulin resistance in the mouse. (2015) (163)
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. (2007) (157)
Faculty Opinions recommendation of miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. (2009) (156)
FXR Deficiency Causes Reduced Atherosclerosis in Ldlr−/− Mice (2006) (155)
NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection (2011) (154)
Paraoxonase-2 Deficiency Aggravates Atherosclerosis in Mice Despite Lower Apolipoprotein-B-containing Lipoproteins (2006) (153)
Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism. (2000) (152)
Using genetic markers to orient the edges in quantitative trait networks: The NEO software (2008) (150)
Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet. (1994) (150)
Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females (2016) (148)
Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA (2018) (147)
Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association. (2017) (146)
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. (2005) (143)
Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. (1998) (142)
Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. (2017) (141)
Association between serum amyloid A proteins and coronary artery disease: evidence from two distinct arteriosclerotic processes. (1997) (140)
Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism. (1997) (139)
Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. (2007) (138)
Genetic factors controlling structure and expression of apolipoproteins B and E in mice. (1987) (137)
Genome Scan for Blood Pressure in Dutch Dyslipidemic Families Reveals Linkage to a Locus on Chromosome 4p (2001) (136)
Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance (2019) (136)
Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics (2007) (135)
Hepatocellular carcinoma in Txnip-deficient mice (2006) (133)
Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. (1993) (132)
Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages (2012) (130)
Mice Lacking Thioredoxin-interacting Protein Provide Evidence Linking Cellular Redox State to Appropriate Response to Nutritional Signals* (2004) (129)
Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9. (1996) (129)
Cardiovascular networks: systems-based approaches to cardiovascular disease. (2010) (129)
A multi-tissue full lifespan epigenetic clock for mice (2018) (128)
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits (2012) (127)
Genetics of atherosclerosis. (2004) (125)
Role of the GRO family of chemokines in monocyte adhesion to MM-LDL-stimulated endothelium. (1994) (123)
Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. (1996) (122)
Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (121)
Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins. (1983) (120)
Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks (2009) (120)
Expression of human paraoxonase (PON1) during development. (2003) (119)
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells (2007) (119)
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits. (2017) (117)
Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet. (1999) (116)
The allelic structure of common disease. (2002) (115)
The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits (2016) (114)
Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis (2011) (114)
The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases (2017) (114)
Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains (2015) (113)
Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci (2013) (113)
Network for Activation of Human Endothelial Cells by Oxidized Phospholipids: A Critical Role of Heme Oxygenase 1 (2011) (113)
A treasure trove for lipoprotein biology (2008) (112)
Systems genetics analysis of gene-by-environment interactions in human cells. (2010) (112)
Identification of Pathways for Atherosclerosis in Mice: Integration of Quantitative Trait Locus Analysis and Global Gene Expression Data (2007) (111)
IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure (2018) (109)
Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine (2014) (109)
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis (2017) (109)
Sequence and Mapping of Galectin-5, a β-Galactoside-binding Lectin, Found in Rat Erythrocytes (*) (1995) (108)
Association of the APOLIPOPROTEIN A1/C3/A4/A5 Gene Cluster With Triglyceride Levels and LDL Particle Size in Familial Combined Hyperlipidemia (2004) (108)
Anti-miR-33 Therapy Does Not Alter the Progression of Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice (2013) (108)
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. (2004) (107)
Transgenic Expression of Cholesterol‐7‐&agr;‐Hydroxylase Prevents Atherosclerosis in C57BL/6J Mice (2002) (107)
Mapping a gene for combined hyperlipidaemia in a mutant mouse strain (1998) (105)
Copy number variation influences gene expression and metabolic traits in mice. (2009) (104)
Genetic Basis of Atherosclerosis: Part II: Clinical Implications (2004) (104)
Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men (2013) (103)
The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene. (1987) (103)
Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. (2003) (102)
ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response. (2008) (102)
Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach. (1995) (102)
Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease (2016) (102)
Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human. (1996) (100)
Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene. (1986) (100)
Expression Quantitative Trait Loci: Replication, Tissue- and Sex-Specificity in Mice (2010) (98)
Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA. (1987) (98)
Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. (1986) (98)
Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12. (1992) (98)
Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. (2018) (98)
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes (2006) (96)
Atherosclerosis: Recent developments (2022) (96)
Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin: cholesterol acyltransferase gene. Evidence for expression in brain and testes as well as liver. (1989) (96)
Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance. (2001) (94)
Genetic and developmental regulation of the lipoprotein lipase gene: loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression. (1989) (94)
THIOREDOXIN-INTERACTING PROTEIN: A CRITICAL LINK BETWEEN GLUCOSE TOXICITY AND BETA CELL APOPTOSIS (2007) (94)
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism (2005) (94)
A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition. (1990) (93)
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential (2018) (92)
Decreased Obesity and Atherosclerosis in Human Paraoxonase 3 Transgenic Mice (2007) (92)
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1). (2000) (91)
Genetic Locus in Mice That Blocks Development of Atherosclerosis Despite Extreme Hyperlipidemia (2001) (91)
Familial Combined Hyperlipidemia in Mexicans: Association With Upstream Transcription Factor 1 and Linkage on Chromosome 16q24.1 (2005) (91)
Granulocyte Macrophage Colony-Stimulating Factor Regulates Dendritic Cell Content of Atherosclerotic Lesions (2007) (90)
Understanding the sexome: measuring and reporting sex differences in gene systems. (2012) (90)
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (2005) (89)
Systems-based approaches to cardiovascular disease (2012) (89)
Identification of CAD candidate genes in GWAS loci and their expression in vascular cells[S] (2013) (89)
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci (2015) (88)
Paradoxical Reduction of Fatty Streak Formation in Mice Lacking Endothelial Nitric Oxide Synthase (2002) (88)
The Murine Chemokine CXCL11 (IFN-Inducible T Cell α Chemoattractant) Is an IFN-γ- and Lipopolysaccharide- Inducible Glucocorticoid-Attenuated Response Gene Expressed in Lung and Other Tissues During Endotoxemia1 (2000) (87)
Genomic analysis of metabolic pathway gene expression in mice (2005) (86)
"Good enough solutions" and the genetics of complex diseases. (2012) (86)
Maternal Low-Protein Diet or Hypercholesterolemia Reduces Circulating Essential Amino Acids and Leads to Intrauterine Growth Restriction (2009) (86)
Complete cDNA and derived protein sequence of human apolipoprotein B-100. (1986) (86)
Systemic Rather Than Local Heme Oxygenase-1 Overexpression Improves Cardiac Allograft Outcomes in a New Transgenic Mouse1 (2003) (85)
Genetic determination of cartilaginous metaplasia in mouse aorta. (1995) (83)
Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene. (2001) (83)
The roles of PON1 and PON2 in cardiovascular disease and innate immunity (2009) (83)
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis (2015) (83)
Genome-tagged mice (GTM): two sets of genome-wide congenic strains. (2001) (82)
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems (2016) (82)
Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk (2018) (81)
Assignment of human 3-hydroxy-3-methylglutaryl coenzyme A reductase gene to q13 → q23 region of chromosome 5 (1986) (81)
Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice. (1993) (81)
Thematic review series: The Pathogenesis of Atherosclerosis. Toward a biological network for atherosclerosiss⃞s⃞ The online version of this article (available at http://www.jlr.org) contains an additional table. Published, JLR Papers in Press, August 1, 2004. DOI 10.1194/jlr.R400006-JLR200 (2004) (81)
Excess of Rare Variants in Non–Genome-Wide Association Study Candidate Genes in Patients With Hypertriglyceridemia (2012) (81)
An integrative systems genetic analysis of mammalian lipid metabolism (2019) (81)
The genetic architecture of NAFLD among inbred strains of mice (2015) (81)
Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival (2017) (81)
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. (2005) (80)
Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice (2006) (80)
Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model. (1993) (80)
Genetic loci determining bone density in mice with diet-induced atherosclerosis. (2001) (78)
Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. (2017) (78)
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. (2015) (78)
Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit. (1985) (77)
Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces. (2015) (76)
Genetic control of lipid transport in mice. I. Structural properties and polymorphisms of plasma lipoproteins. (1983) (76)
Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo. (1995) (76)
Apolipoprotein AII Is a Regulator of Very Low Density Lipoprotein Metabolism and Insulin Resistance* (2008) (75)
Paraoxonase-gene polymorphisms associated with coronary heart disease: support for the oxidative damage hypothesis? (1998) (75)
Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400341-JLR200 (2005) (75)
Regulation of chicken apolipoprotein B: cloning, tissue distribution, and estrogen induction of mRNA. (1987) (75)
Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus (2017) (74)
Characterization of the Murine μ Opioid Receptor Gene (*) (1995) (74)
Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury (2020) (74)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (73)
Open Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat Diet* (2014) (73)
Gene networks associated with conditional fear in mice identified using a systems genetics approach (2011) (73)
Structure, evolution, and regulation of chicken apolipoprotein A-I. (1987) (72)
Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis (2001) (72)
Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis. (1990) (72)
Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti‐inflammatory response (2015) (71)
A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. (1996) (70)
The problem of passenger genes in transgenic mice. (2007) (70)
Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice (2003) (70)
Genetic control of HDL levels and composition in an interspecific mouse cross (CAST/Ei x C57BL/6J). (2000) (70)
Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits. (2013) (69)
Null mutation of myeloperoxidase in mice prevents mechanical activation of neutrophil lysis of muscle cell membranes in vitro and in vivo (2005) (69)
Purification and characterization of a human T-lymphocyte-derived granulocyte-macrophage colony-stimulating factor (1981) (68)
The gene for human liver arginase (ARG1) is assigned to chromosome band 6q23. (1986) (68)
Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice. (2006) (67)
Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. (2019) (67)
Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model (2016) (66)
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States (2017) (66)
Cloning and regulation of messenger RNA for mouse apolipoprotein E. (1984) (66)
Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. (1996) (66)
Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus. (1998) (66)
Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid[S] (2013) (65)
The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle (2018) (65)
ApoE−/−Fas−/− C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia Published, JLR Papers in Press, January 26, 2007. (2007) (65)
Endogenous natural killer enhancing factor-B increases cellular resistance to oxidative stresses. (1997) (65)
Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease (2019) (64)
Sex differences in metabolism and cardiometabolic disorders (2018) (63)
Transgenic mice express human MPO −463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in −463G males Published, JLR Papers in Press, April 25, 2006. (2006) (63)
Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-Adrenergic Stimulation in Mice (2015) (63)
In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions. (2001) (62)
Genetic determination of the α-galactosidase developmental program in mice (1975) (62)
Impaired Development of Atherosclerosis in Abcg1−/− Apoe−/− Mice: Identification of Specific Oxysterols That Both Accumulate in Abcg1−/− Apoe−/− Tissues and Induce Apoptosis (2010) (62)
Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report (2010) (62)
High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock (2008) (62)
Direct gene transfer into donor hearts at the time of harvest. (1995) (61)
Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene. (1993) (61)
Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF. (1992) (61)
Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome (2018) (61)
Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message. (1991) (60)
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS (2018) (60)
Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota. (2015) (60)
Association of Stearoyl-CoA Desaturase 1 Activity With Familial Combined Hyperlipidemia (2008) (60)
Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss (2015) (60)
A Novel Family of Cys-Cys, His-Cys Zinc Finger Transcription Factors Expressed in Developing Nervous System and Pituitary Gland (*) (1996) (60)
Immune-complex-mediated vasculitis increases coronary artery lipid accumulation in autoimmune-prone MRL mice. (1993) (59)
Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis[S] (2010) (59)
Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model : interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis. (1999) (59)
Secretory non-pancreatic phospholipase A2: influence on lipoprotein metabolism. (1997) (59)
RFLP for the human lipoprotein lipase (LPL) gene: HindIII. (1987) (58)
DNA polymorphism haplotypes of the human lipoprotein lipase gene: possible association with high density lipoprotein levels (1991) (58)
Apolipoprotein B mRNA editing. Direct determination of the edited base and occurrence in non-apolipoprotein B-producing cell lines. (1990) (58)
Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice. (1991) (58)
Early Hepatic Insulin Resistance Precedes the Onset of Diabetes in Obese C57BLKS-db/db Mice (2010) (57)
Using Mice to Dissect Genetic Factors in Atherosclerosis (2003) (57)
An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association (2009) (57)
Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. (2014) (57)
Estrogen Receptor (ER)α-regulated Lipocalin 2 Expression in Adipose Tissue Links Obesity with Breast Cancer Progression* (2014) (56)
Alteration of lipid profiles in plasma of transgenic mice expressing human lipoprotein lipase. (1994) (56)
High-Density Lipoprotein Modulates Oxidized Phospholipid Signaling in Human Endothelial Cells From Proinflammatory to Anti-inflammatory (2007) (55)
Allele-specific expression and eQTL analysis in mouse adipose tissue (2014) (55)
Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease (2018) (55)
Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene. (1986) (54)
Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice. (2004) (54)
Integrating global gene expression analysis and genetics. (2008) (54)
Zbtb16 has a role in brown adipocyte bioenergetics (2012) (54)
Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. (1992) (53)
Loss of the Lysophosphatidylcholine Effector, G2A, Ameliorates Aortic Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice (2006) (53)
Isolation, characterization, and radioimmunoassay of murine egasyn, a protein stabilizing glucuronidase membrane binding. (1976) (53)
Cloning and expression of apolipoprotein B, the major protein of low and very low density lipoproteins. (1985) (53)
A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity* (2009) (53)
Identification and validation of genes affecting aortic lesions in mice. (2010) (53)
A comparison between whole transcript and 3’ RNA sequencing methods using Kapa and Lexogen library preparation methods (2019) (52)
Locus for Elevated Apolipoprotein B Levels on Chromosome 1p31 in Families With Familial Combined Hyperlipidemia (2002) (52)
Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. (1996) (52)
Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. (2008) (51)
Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis (2010) (51)
USF1 Contributes to High Serum Lipid Levels in Dutch FCHL Families and U.S. Whites With Coronary Artery Disease (2007) (51)
Genetic regulation of mouse liver metabolite levels (2014) (51)
Mouse cellular nucleic acid binding proteins: a highly conserved family identified by genetic mapping and sequencing. (1994) (50)
The PON1 gene and detoxication. (2000) (50)
The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice (2018) (50)
Systems Genetic Analysis of Osteoblast-Lineage Cells (2012) (50)
New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. (2001) (50)
Testing the iron hypothesis in a mouse model of atherosclerosis. (2013) (49)
Shared Molecular Pathways and Gene Networks for Cardiovascular Disease and Type 2 Diabetes Mellitus in Women Across Diverse Ethnicities (2014) (49)
Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity (2020) (49)
BSB: a new mouse model of multigenic obesity. (1993) (49)
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism. (2018) (48)
Identification of ALOX5 as a gene regulating adiposity and pancreatic function (2008) (48)
Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. (2015) (48)
Quantitative Trait Locus Analysis of Atherosclerosis in an Intercross Between C57BL/6 and C3H Mice Carrying the Mutant Apolipoprotein E Gene (2006) (48)
A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids Published, JLR Papers in Press, November 3, 2005. (2006) (48)
Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages. (1999) (48)
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. (2021) (47)
RIPK1 Expression Associates with Inflammation in Early Atherosclerosis in Humans and Can be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice. (2020) (47)
Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1. (1991) (47)
Effect of 9p21.3 Coronary Artery Disease Locus Neighboring Genes on Atherosclerosis in Mice (2012) (47)
Lipoprotein oxidation and gene expression in the artery wall. New opportunities for pharmacologic intervention in atherosclerosis. (1993) (47)
A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear (2016) (46)
Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. (1992) (46)
Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice Published, JLR Papers in Press, April 16, 2005. DOI 10.1194/jlr.M500085-JLR200 (2005) (45)
Analysis of Allele-Specific Expression in Mouse Liver by RNA-Seq: A Comparison With Cis-eQTL Identified Using Genetic Linkage (2013) (45)
Familial combined hyperlipidemia: upstream transcription factor 1 and beyond (2006) (45)
Vestigial-like 3 is an inhibitor of adipocyte differentiation[S] (2013) (45)
The apolipoprotein(a) gene resides on human chromosome 6q26–27, in close proximity to the homologous gene for plasminogen (1988) (45)
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling (2020) (45)
XX sex chromosome complement promotes atherosclerosis in mice (2019) (45)
Mouse apolipoprotein A-IV gene: nucleotide sequence and induction by a high-lipid diet (1986) (45)
Mapping, Genetic Isolation, and Characterization of Genetic Loci That Determine Resistance to Atherosclerosis in C3H Mice (2007) (44)
Quantitative Trait Locus Mapping and Identification of Zhx2 as a Novel Regulator of Plasma Lipid Metabolism (2010) (44)
Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease (2013) (43)
Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci (1994) (43)
Atherosclerosis: Association between the gut microbiome and atherosclerosis (2017) (43)
Lipin-1 and lipin-3 together determine adiposity in vivo. (2014) (43)
Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity (2018) (42)
Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase. (1993) (42)
Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis (2018) (42)
Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter. (1991) (41)
Biochemical and Genetic Association of Plasma Apolipoprotein A‐II Levels With Familial Combined Hyperlipidemia (2003) (41)
Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism. (1998) (41)
Nucleotide sequence of rat adipose hormone sensitive lipase cDNA. (1988) (41)
Chromosomal organization of the inducible and constitutive prostaglandin synthase/cyclooxygenase genes in mouse. (1993) (41)
Lipoprotein (a) displays increased accumulation compared with low-density lipoprotein in the murine arterial wall. (1994) (41)
Systems genetics of susceptibility to obesity-induced diabetes in mice. (2012) (41)
Abcc6 Deficiency Causes Increased Infarct Size and Apoptosis in a Mouse Cardiac Ischemia-Reperfusion Model (2011) (40)
Description of two different patients with abetalipoproteinemia: synthesis of a normal-sized apolipoprotein B-48 in intestinal organ culture. (1990) (40)
Genome-wide association mapping of blood cell traits in mice (2013) (40)
Oxidized lipoproteins influence gene expression by causing oxidative stress and activating the transcription factor NF-kappa B. (1993) (40)
Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice (2014) (40)
Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease. (2019) (40)
The beta-glucosidase system of the thermophilic fungus Chaetomium thermophile var. coprophile n. var. (1973) (40)
Genetic factors in cardiovascular disease. 10 questions. (2003) (39)
Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility. (2005) (39)
Structure and chromosomal localization of the murine gene encoding GLYCAM 1. A mucin-like endothelial ligand for L selectin. (1993) (39)
Systems biology asks new questions about sex differences (2009) (39)
A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci (2009) (39)
Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. (1993) (39)
Future Translational Applications From the Contemporary Genomics Era: A Scientific Statement From the American Heart Association (2015) (39)
An Absorbing Study of Cholesterol (2000) (38)
Heritability and genetic loci of fatty liver in familial combined hyperlipidemia Published, JLR Papers in Press, September 13, 2006. (2006) (38)
Carboxyl ester lipase: a highly polymorphic locus on human chromosome 9qter. (1991) (38)
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice (2021) (38)
Complex Inheritance of the 5-Lipoxygenase Locus Influencing Atherosclerosis in Mice (2006) (38)
ABCC6 Localizes to the Mitochondria-Associated Membrane (2012) (38)
Dissection of multigenic obesity traits in congenic mouse strains (2003) (38)
LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice[S] (2012) (38)
A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background. (2005) (38)
Intergenerational genomic DNA methylation patterns in mouse hybrid strains (2014) (37)
Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression (2017) (37)
Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism (2019) (37)
DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. (2016) (37)
Linkage of genetic determinants for mouse beta-galactosidase electrophoresis and activity. (1977) (36)
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity (2020) (36)
Evidence for independent genetic regulation of heart and adipose lipoprotein lipase activity. (1983) (36)
New insights into atherosclerosis from studies with mouse models. (1995) (36)
Trans-acting temporal locus within the beta-glucuronidase gene complex. (1983) (35)
PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis (2015) (35)
Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice. (2010) (35)
The mouse model for atherosclerosis. (1993) (35)
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection (2021) (35)
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells (2018) (35)
Novel gene exon homologous to pancreatic phospholipase A2: Sequence and chromosomal mapping of both human genes (1989) (35)
Sequence, Structure, and Chromosomal Mapping of the MouseLgals6 Gene, Encoding Galectin-6* (1998) (35)
PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. (2013) (35)
A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. (2005) (35)
Trimethylamine N-Oxide levels are associated with NASH in obese subjects with type 2 diabetes. (2020) (35)
Genetic markers for studies of atherosclerosis and related risk factors (1992) (34)
Modified Lipoproteins and Atherogenesis (1992) (34)
Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway[S] (2016) (34)
Serum amyloid A protein family. Differential induction by oxidized lipids in mouse strains. (1994) (33)
Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF. (1992) (33)
Dilated cardiomyopathy: learning to live with yourself (2003) (33)
Reviews, Notes, and Listings: Cardiology: Molecular Genetics of Coronary Artery Disease: Candidate Genes and Processes in Atherosclerosis (1992) (33)
Localization and evolution of two human phospholipase A2 genes and two related genetic elements. (1990) (33)
Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12-16q21. (1987) (33)
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. (2019) (33)
The large scale isolation of mouse beta-glucuronidase and comparison of allozymes. (1978) (33)
Genetic loci influencing natural variations in femoral bone morphometry in mice (2001) (33)
Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice. (2006) (32)
Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26. (1991) (32)
Paraoxonase-2 Modulates Stress Response of Endothelial Cells to Oxidized Phospholipids and a Bacterial Quorum–Sensing Molecule (2011) (32)
Gene Expression Analyses of Mouse Aortic Endothelium in Response to Atherogenic Stimuli (2013) (32)
Genome-wide screening for genetic loci associated with noise-induced hearing loss (2009) (32)
Effect of Macrophage-Derived Apolipoprotein E on Established Atherosclerosis in Apolipoprotein E–Deficient Mice (2000) (32)
A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2. (2000) (31)
Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice (2012) (31)
Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes (2016) (31)
Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR‐knockout mice (2013) (31)
Assignment of the human gene for CREB1 to chromosome 2q32.3-q34. (1990) (31)
cis-acting determinants of basal and lipid-regulated apolipoprotein A-IV expression in mice. (1989) (31)
Induction of chemotactic cytokines by minimally oxidized LDL. (1993) (31)
Imputing Phenotypes for Genome-wide Association Studies. (2016) (30)
A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. (2012) (30)
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids (2008) (30)
Structure of the murine tissue factor gene. Chromosome location and conservation of regulatory elements in the promoter. (1992) (30)
Genome-Wide Association Study for Age-Related Hearing Loss (AHL) in the Mouse: A Meta-Analysis (2014) (30)
Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis (2020) (30)
Evolutionary distinct mechanisms regulate apolipoprotein A-I gene expression: differences between avian and mammalian apoA-I gene transcription control regions. (1992) (30)
Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. (2017) (30)
Genetic Backgrounds but Not Sizes of Atherosclerotic Lesions Determine Medial Destruction in the Aortic Root of Apolipoprotein E–Deficient Mice (2003) (30)
Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice. (2005) (30)
Genome Scans for Transmission Ratio Distortion Regions in Mice (2012) (29)
Macrophage accumulation in atherosclerosis. (2013) (29)
Future of Osteoporosis Genetics: Enhancing Genome‐Wide Association Studies (2009) (29)
Genetic Factors in Susceptibility: Serum PON1 Variation Between Individuals and Species (2002) (29)
Regulation of NF-κB signaling by oxidized glycerophospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic endothelial cells[S] (2015) (29)
Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding. (1994) (29)
Genetic and hormonal control of hepatic steatosis in female and male mice1[S] (2016) (29)
High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping (2015) (29)
Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. (1993) (29)
Quantitative Trait Loci for Apolipoprotein B, Cholesterol, and Triglycerides in Familial Combined Hyperlipidemia Pedigrees (2004) (28)
Systems genetics applications in metabolism research (2019) (28)
Human apolipoprotein B: partial amino acid sequence (1984) (28)
Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits. (2019) (28)
Sex-specific metabolic functions of adipose Lipocalin-2 (2019) (28)
Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application (2015) (28)
Limited RNA Editing in Exons of Mouse Liver and Adipose (2013) (28)
Atherosclerosis in C3H/HeJ Mice Reconstituted With Apolipoprotein E-Null Bone Marrow (2002) (28)
Genetics of common forms of heart failure: challenges and potential solutions (2015) (27)
Conducting the metabolic syndrome orchestra (2011) (27)
FAM13A affects body fat distribution and adipocyte function (2020) (27)
Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: analysis of a large pedigree from the Bogalusa Heart Study. (1993) (27)
Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis. (2010) (27)
Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons. (1991) (27)
Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5 (2002) (27)
Mapping of the gene for the cardiac sarcolemmal Na(+)-Ca2+ exchanger to human chromosome 2p21-p23. (1992) (26)
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (26)
Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling. (2009) (26)
Epigenome-wide association in adipose tissue from the METSIM cohort (2018) (26)
Heritability of periodontal bone loss in mice. (2015) (26)
The Functional Consequences of Polymorphisms in the Human PON1 Gene (2008) (26)
ApoA-II versus ApoA-I: two for one is not always a good deal. (2001) (26)
Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein. (1998) (26)
Hyplip2, a New Gene for Combined Hyperlipidemia and Increased Atherosclerosis (2004) (25)
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution. (2019) (25)
Nongenetic heterogeneity of mouse beta-galactosidase. (1977) (25)
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease (2021) (25)
Chromatin variation associated with liver metabolism is mediated by transposable elements (2016) (25)
Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. (1994) (25)
Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis (2018) (25)
A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure (2018) (24)
The State of Systems Genetics in 2017. (2017) (24)
The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction (2016) (24)
Genetic control of the inflammatory response induced by oxidized lipids. (1995) (24)
Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II Published, JLR Papers in Press, October 1, 2004. DOI 10.1194/jlr.M400345-JLR200 (2004) (24)
Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia and Liver Steatosis. (2019) (24)
Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf (2016) (23)
FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. (2007) (23)
Lipid retention in the arterial wall of two mouse strains with different atherosclerosis susceptibility Published, JLR Papers in Press, March 16, 2004. DOI 10.1194/jlr.M400092-JLR200 (2004) (23)
Genetic locus on mouse chromosome 7 controls elevated heart rate. (2012) (23)
Maximal information component analysis: a novel non-linear network analysis method (2013) (23)
Apolipoprotein B-100 Hopkins (arginine4019----tryptophan). A new apolipoprotein B-100 variant in a family with premature atherosclerosis and hyperapobetalipoproteinemia. (1989) (23)
Action of granulocyte-macrophage colony-stimulating factors: studies using a human leukemia cell line. (1980) (23)
Biosynthetic relationships between three rat apolipoprotein B peptides. (1988) (22)
Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation* (2015) (22)
Human apolipoprotein B: Chromosomal mapping and DNA polymorphisms of hepatic and intestinal species (1986) (22)
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes (2021) (22)
Chromosomal organization of mammalian POU domain factors. (1993) (22)
Transgenic Expression of Dominant-Active IDOL in Liver Causes Diet-Induced Hypercholesterolemia and Atherosclerosis in Mice (2014) (22)
Systems toxicogenomics of prenatal low-dose BPA exposure on liver metabolic pathways, gut microbiota, and metabolic health in mice (2020) (22)
Genetic variation in mouse apolipoprotein A-IV expression is determined pre- and post-transcriptionally. (1993) (21)
Genomewide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS‐Induced Periodontitis (2018) (21)
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR[S] (2018) (21)
Erratum: The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue (Cell Reports (2017) 19(12) (2451–2461) (S2211124717307519) (10.1016/j.celrep.2017.05.077)) (2017) (21)
Roles of Macrophages in Atherogenesis (2021) (21)
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner (2020) (21)
CHD and Atherosclerosis: Human Epidemiological Studies and Transgenic Mouse Models (2002) (21)
Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development. (1993) (20)
Relationships between levels of membrane-bound glucuronidase and the associated protein egasyn in mouse tissues (1977) (20)
Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice. (2004) (20)
A mechanistic framework for cardiometabolic and coronary artery diseases (2022) (20)
Properties of mouse alpha-galactosidase. (1976) (20)
Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. (2016) (20)
Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD[S] (2016) (20)
Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain. (2004) (20)
PON1 and Organophosphate Toxicity (2002) (20)
Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. (1993) (19)
Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice (2018) (19)
The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglyceridess⃞ Published, JLR Papers in Press, July 3, 2007. (2007) (19)
Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. (1989) (19)
Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data (2016) (19)
Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL (2001) (19)
Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure (2019) (19)
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice (2015) (19)
Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism (2021) (19)
Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure (2016) (18)
simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia (2007) (18)
Disruption of the Aortic Elastic Lamina and Medial Calcification Share Genetic Determinants in Mice (2009) (18)
Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to High Fructose Consumption in Mice (2018) (18)
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2 (2021) (18)
Genetic characterization of the Dyscalc locus (2002) (18)
Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus (2017) (18)
The Ca2+ transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations (2018) (17)
Increasing Association Mapping Power and Resolution in Mouse Genetic Studies Through the Use of Meta-Analysis for Structured Populations (2012) (17)
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle. (2021) (17)
Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model (2020) (17)
Mechanisms involved in the intracellular localization of mouse glucuronidase. (1977) (17)
Metalloproteinase Processing of HBEGF Is a Proximal Event in the Response of Human Aortic Endothelial Cells to Oxidized Phospholipids (2012) (17)
Mechanisms controlling competence gene expression in murine fibroblasts stimulated with minimally modified LDL. (1992) (17)
Assignment of the human pancreatic colipase gene to chromosome 6p21.1 to pter. (1991) (16)
Genetic control of plasma lipid transport: mouse model. (1986) (16)
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms (2020) (16)
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity (2021) (16)
Thioredoxin-Interacting Protein : A Critical Link Between Glucose Toxicity and β-Cell Apoptosis. Commentary (2008) (16)
Identifying loci for behavioral traits using genome‐tagged mice (2003) (16)
Translation of mRNA for human granulocyte–macrophage colony stimulating factor (1982) (16)
Genetic factors in atherosclerosis : approaches and model systems (1989) (16)
High-Resolution Association Mapping of Atherosclerosis Loci in Mice (2012) (15)
Systems Genetics Analysis of Mouse Chondrocyte Differentiation (2010) (15)
Abcc 6 Deficiency Causes Increased Infarct Size and Apoptosis in a Mouse Cardiac Ischemia-Reperfusion Model (2011) (15)
A systems-based framework for understanding complex metabolic and cardiovascular disorders Published, JLR Papers in Press, November 24, 2008. (2009) (15)
Genetic loci contributing to age-related hippocampal lesions in mice (2003) (15)
Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains (2016) (15)
The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants (2015) (15)
Genetic Regulation of Atherosclerotic Plaque Size and Morphology in the Innominate Artery of Hyperlipidemic Mice (2009) (15)
ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities. (2003) (15)
Genetics of atherosclerosis: The search for genes acting at the level of the vessel wall (2000) (14)
Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24. (1991) (14)
The Systems Genetics Resource: A Web Application to Mine Global Data for Complex Disease Traits (2013) (14)
β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity (2021) (14)
Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms (2016) (14)
The L-isoaspartyl/D-aspartyl protein methyltransferase gene (PCMT1) maps to human chromosome 6q22.3-6q24 and the syntenic region of mouse chromosome 10. (1992) (14)
Placental genomics mediates genetic associations with complex health traits and disease (2022) (13)
Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity[S] (2019) (13)
The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes. (2019) (13)
Adrenocortical Lipid Depletion Gene (ald) in AKR Mice Is Associated with an Acyl-CoA:Cholesterol Acyltransferase (ACAT) Mutation* (1998) (13)
Paraoxonase 1 (PON1) status and risk of insecticide exposure (2005) (13)
Allelic Variation on Murine Chromosome 11 Modifies Host Inflammatory Responses and Resistance to Bacillus anthracis (2011) (13)
Impact of Chromosome 2 Obesity Loci on Cardiovascular Complications of Insulin Resistance in LDL Receptor–Deficient C57BL/6 Mice (2006) (13)
Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans (2018) (13)
Association of the APOLIPOPROTEIN A 1 / C 3 / A 4 / A 5 Gene Cluster With Triglyceride Levels and LDL Particle Size in Familial Combined Hyperlipidemia (2004) (12)
Genetics of human gut microbiome composition (2020) (12)
Biologic modification of the immune response in mouse cardiac isografts using gene transfer. (1995) (12)
Noggin depletion in adipocytes promotes obesity in mice (2019) (12)
Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure (2022) (12)
Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum (2017) (12)
Localization of the gene for high-density lipoprotein binding protein (HDLBP) to human chromosome 2q37. (1993) (12)
Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation. (1997) (12)
A gene homologous to plasminogen located on human chromosome 2q11-p11. (1989) (12)
A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse Chromosome 19 (1998) (12)
Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans (2016) (12)
Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation (2015) (11)
A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. (2017) (11)
genes in mice Tissue-specific expression and regulation of sexually dimorphic Material Supplemental (2006) (11)
Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis (2019) (11)
Multiple structural genes for mouse amylase (1980) (11)
X-linked and autosomal genes controlling mouse alpha-galactosidase expression. (1978) (11)
Machine Learning Reveals Time-Varying Microbial Predictors with Complex Effects on Glucose Regulation (2020) (11)
Mapping behavioral traits by use of genome-tagged mice. (2004) (11)
PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity (2019) (11)
Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. (2010) (11)
Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery (2014) (11)
Identification of New Genes Contributing to Atherosclerosis: The Mapping of Genes Contributing to Complex Disorders in Animal Models (1992) (11)
Amino-terminal amino acid sequence of murine colony-stimulating factor 1. (1985) (11)
The Transcription Factor MAFF Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. (2021) (11)
Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice (1994) (10)
Fitting pieces from studies of animal models into the puzzle of atherosclerosis (1992) (10)
Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development (2017) (10)
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential (2018) (10)
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes (2021) (10)
ATF 4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids : critical role of oxidized sn2 residues in activation of unfolded protein response * (2008) (10)
Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease. (2021) (10)
Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24. (1990) (10)
Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line. (1990) (10)
Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1 (2018) (9)
Localization of the gene for apolipoprotein D on mouse chromosome 16. (1992) (9)
Understanding atherosclerosis through mouse genetics (2002) (9)
Localization of the transcription factor SP1 gene to human chromosome 12q12-->q13.2. (1993) (9)
Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2. (1993) (9)
Life after GWAS: functional genomics in vascular biology. (2012) (9)
Animal models for genetic lipoprotein disorders (1990) (9)
Linkage of the mouse LDL receptor gene on chromosome 9. (1989) (9)
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis (2021) (9)
The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice (2020) (9)
Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency. (2016) (9)
Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene. (1993) (9)
Apolipoprotein B Gene Haplotypes: Association between Ag and DNA Polymorphisms (1988) (8)
Longitudinal differences in familial combined hyperlipidemia quantitative trait loci. (2006) (8)
A vicious cycle in atherosclerosis (2021) (8)
Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. (2019) (8)
Sex differences in heart mitochondria regulate diastolic dysfunction (2022) (8)
Oxy210, a novel inhibitor of hedgehog and TGF‐β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice (2021) (8)
Apolipoprotein A-II: a protein in search of a function. (1994) (8)
Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation (2014) (8)
X-linked inheritance of a structural gene for alpha-galactosidase in Mus musculus. (1976) (8)
The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. (2017) (7)
Molecular Cloning and Functional Expression of Murine JE (Monocyte Chemoattractant Protein 1) and Murine Macrophage Inflammatory Protein 1 Receptors (1996) (7)
Localization of the δ-Opioid Receptor Gene to Mouse Chromosome 4 by Linkage Analysis (1994) (7)
NIH3T3 transforming gene not a general feature of atherosclerotic plaque DNA (atherosclerosis/oncogene/NIH3T3 transfection assay). (1989) (7)
Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide (2021) (7)
Mapping of the gene for high-density lipoprotein binding protein (Hdlbp) to proximal mouse chromosome 1. (1994) (7)
Quantitation of cis versus trans regulation of mouse beta-glucuronidase. Action of alleles of the Gus-r locus determining androgen inducibility. (1980) (7)
Linkage between the APOB gene and serum apoB levels in a large pedigree from the Bogalusa heart study (1994) (7)
HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms[S] (2014) (7)
Trimethylamine N-Oxide Promotes Vascular In ﬂ ammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor- j B (2016) (7)
Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice. (2017) (7)
ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney (2015) (7)
Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice (2020) (6)
Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (6)
Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring (2018) (6)
Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity (2022) (6)
Systems Genetics for Mechanistic Discovery in Heart Diseases (2020) (6)
Assignment of the gene for cyclic AMP-response element binding protein 2 (CREB2) to human chromosome 2q24.1-q32. (1991) (6)
Genetic Regulation of Expression of Mammalian Lysosomal Enzymes (1982) (6)
Fecal Microbiome Composition Does Not Predict Diet‐Induced TMAO Production in Healthy Adults (2021) (6)
Systems-based approaches for investigation of inter-tissue communication[S] (2019) (6)
The Nutritional Supplement L-Alpha Glycerylphosphorylcholine Promotes Atherosclerosis. (2021) (6)
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits (2012) (5)
DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains (2019) (5)
Erratum: Epigenome-wide association in adipose tissue from the METSIM cohort [Human Molecular Genetics., 27, 10, (2018), (1830-1846)] DOI: 10.1093/hmg/ddy093 (2018) (5)
A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel. (2017) (5)
A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity (2019) (5)
Two polymorphisms for the human hepatic lipase (HL) gene. (1988) (5)
Using the natural variation of mouse populations to understand host-gut microbiome interactions. (2018) (5)
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair (2022) (5)
X-linked inheritance of a structural gene for α-galactosidease in Mus musculus (1976) (4)
Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico (2021) (4)
Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease (2021) (4)
Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice. (2006) (4)
Cardiovascular disease genes come together. (2015) (4)
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice (2020) (4)
Srbl maps to mouse Chromosome 5 in a region harboring putative QTLs for plasma lipoprotein levels (1997) (4)
Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for “polygenic epistasis” (2019) (4)
Biochemical and Genetic Association of Plasma Apolipoprotein AII Levels With Familial Combined Hyperlipidemia (2003) (4)
Genetics of common forms of heart disease: a long and winding road. (2013) (4)
Mouse chromosomal localization of the cortexin (Ctxn) gene. (1994) (4)
Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. (2016) (4)
Epigenome-wide association in adipose tissue from the METSIM cohort. (2018) (4)
Mapping of the gene for calreticulin (Calr) to mouse Chromosome 8 (2009) (4)
The β-glucosidase system of the thermophilic fungus Chaetomium thermophile (1973) (4)
Cytotoxicity of anti-beta 2-microglobulin xenoantisera to human and murine myeloid progenitor cells and lack of cross-reactivity with colony-stimulating activity. (1980) (3)
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (vol 37, pg 1224, 2005) (2005) (3)
Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss (2015) (3)
Assignment of the mouse vesicular monoamine transporter genes, Slcl8al and Slcl8a2, to Chromosomes 8 and 19 by linkage analysis (1996) (3)
Hybrid Mouse Diversity Panel Identifies Genetic Architecture Associated with the Acute Antisense Oligonucleotide-Mediated Inflammatory Response to a 2'-O-Methoxyethyl Antisense Oligonucleotide. (2019) (3)
A comparison between whole transcript and 3’ RNA sequencing methods using Kapa and Lexogen library preparation methods (2019) (3)
Preparation of microsomal beta-glucuronidase and its membrane anchor protein, egasyn. (1983) (3)
Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development (2017) (3)
Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid (2008) (3)
A locus on the X Chromosome is linked to body length in mice (1996) (3)
Chromosomal Organization of Genes Involved in Plasma Lipoprotein Metabolism: Human and Mouse ‘Fat Maps’ (1989) (3)
Localization of the delta-opioid receptor gene to mouse chromosome 4 by linkage analysis. (1994) (3)
Response to Pomozi et al's research commentary. (2013) (3)
Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK 2 and JAG 2 (2018) (3)
Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse Chromosome 9 (2009) (3)
Genetic and metabolic influences on LDL subclasses (1994) (3)
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis (fatty acidycloningyexpressed sequence tagyglycerolipid) (1998) (2)
Genome-wide association mapping of blood cell traits in mice (2013) (2)
Use of the lac repressor in constructing sequential deletions and a new sequencing vector. (1990) (2)
Heme Oxygenase and Atherosclerosis (2002) (2)
Y-Chromosome Genetic Variation Associated With Atherosclerosis and Inflammation. (2019) (2)
Sexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3), Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice (2021) (2)
Localization of murine macrophage inducible nitric oxide synthase to mouse chromosome 11. (1994) (2)
Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice (2016) (2)
Identification of the Transcription Factor ATF3 as a Direct and Indirect Regulator of the LDLR (2022) (2)
Localization of ubiquitin gene family members to mouse Chromosomes 5, 11, and 18 (1997) (2)
Efficient and Accurate Multiple-Phenotypes Regression Method for High Dimensional Data Considering Population Structure (2015) (2)
Mechano-Sensitive PPAP 2 B Regulates Endothelial Responses to Athero-Relevant Hemodynamic Forces (2015) (2)
Variability and compensation of cardiomycoyte ionic conductances at the population level (2018) (2)
The Heart has Intrinsic Ketogenic Capacity that is Facultatively Upregulated in Heart Failure with Preserved Ejection Fraction (2021) (2)
Pathologic gene network rewiring implicates PPP1R3A as a central cardioprotective factor in pressure overload heart failure (2016) (2)
Genetic Factors in Atherosclerosis (1998) (2)
Abstract 20762: Diesel Exhaust Induces Hyperlipidemia in Association With Downregulation of PPAR Alpha and Changes in Gut Microbiota (2016) (2)
The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair. (2021) (2)
Genetic control of fetal placental genomics contributes to development of health and disease (2021) (2)
KpnI RFLP for the human CSF-1 gene. (1989) (2)
Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization (2022) (2)
Dietary and Pharmacologic Manipulations of Host Lipids and Their Interaction With the Gut Microbiome in Non-human Primates (2021) (2)
The Effects of Mutations are Modified by Genetic Background in Mice (2019) (2)
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice (2021) (2)
Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach (2022) (2)
Mapping of three members of the mouse protein disulfide isomerase family (1998) (2)
Genetic evidence that the multiple apolipoprotein A-1 isoforms are encoded by a common structural gene. (1983) (2)
8 – Regulation of Location of Intracellular Proteins (1980) (2)
Assignment of Gpam to distal mouse Chromosome 19 by linkage analysis (2009) (1)
Cold-associated mammokines preserve adipocyte identity (2020) (1)
Network-centered view of coronary artery disease (2007) (1)
Faculty Opinions recommendation of A core gut microbiome in obese and lean twins. (2009) (1)
Assignment of the mouse sterol carrier protein gene (Scp2) to Chromosome 4 (1996) (1)
Microbiome/Metabolic Syndrome/Diabetes and CVD (2015) (1)
RNA-Seq Analysis of Allele-Specific Expression in the Mouse Cochlea (2014) (1)
Lipoprotein profiles in transgenic mice expressing human lipoprotein lipase on a regular and high fat diet (1994) (1)
Natriuretic Peptide Receptor 2 Locus Contributes to Carotid Remodeling (2020) (1)
A functional variant of the SIDT2 gene involved in cholesterol transport is associated with HDL-C levels and premature coronary artery disease. (2020) (1)
Genetic control of the HDL proteome (2018) (1)
Genetic determination of the alpha-galactosidase developmental program in mice. (1975) (1)
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut (2023) (1)
Nutrient Metabolism Increased Lipogenesis and Fatty Acid Reesterification Contribute to Hepatic Triacylglycerol Stores in Hyperlipidemic Txnip / Mice 1 , 2 (2004) (1)
Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI–Mediated High-Density Lipoprotein Uptake (2021) (1)
Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene (2004) (1)
Homeostasis of Lipid Oxidation in the Artery Wall (1995) (1)
Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS (2018) (1)
Sex-Specific Role of Adipose-Derived Lipocalin-2 in Diet-Induced Obesity and Insulin Resistance (2018) (1)
Abstract 19020: ABCG1 Regulates Pulmonary Surfactant Homeostasis and the Lung Microbiome (2015) (1)
Identification of DNA Damage Repair Enzyme Ascc2 as Causal for Heart Failure With Preserved Ejection Fraction. (2022) (1)
Allele-specific expression and eQTL analysis in mouse adipose tissue (2014) (1)
Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery (2014) (1)
Gene-Environment Interactions for Cardiovascular Disease (2021) (1)
Localization of mouse peroxisome proliferator-activated receptor gamma on chromosome 6. (1996) (1)
Localization of mouse peroxisome proliferator-activated receptor δ (Ppard) on Chromosome 17 near colipase (Clps) (1996) (1)
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis (2023) (1)
Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy (2021) (1)
Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (1)
Relationship between genetic variation in thermal stability and electrophoretic mobility of mouse beta-galactosidase. (1978) (1)
Abstract 15: Proteomic Analysis of HDL from Inbred Strains of Mice Implicates APOE in Reduced Cholesterol Efflux Capacity via the ABCA1 Pathway (2015) (1)
The glutathione peroxidase gene, Gpx1, maps to mouse Chromosome 9 (1996) (1)
Artery Wall Interactions in Early Atherogenesis (1992) (1)
Abstract 18108: Decreased Fmo3 Expression is Associated With Increased Atherosclerosis and Impaired Liver Function in Apolipoprotein E Null Mice (2013) (1)
Abstract 1207: Ambient Ultrafine Particulate Matter Enhances Atherosclerosis in apoE Null Animals (2006) (1)
A personalized, multi-omics approach identifies genes involved in cardiac hypertrophy and heart failure (2017) (1)
Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017) (2018) (1)
A Novel Tissue Factor Resistance Locus on Mouse Chromosome 11 Confers Protection from Thrombosis through Reduced Activity of Factor XI (2008) (1)
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems (2016) (1)
ScRNA-seq Reveals a Role of Mammary Luminal Epithelium in Adipocyte Adaptations (2021) (1)
Genetic control of heart and adipose lipo protein lipase (1982) (1)
Author response: Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease (2019) (1)
Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice (2014) (1)
The Lands cycle modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle (2019) (1)
Genetic Control of Inflammatory Gene Induction and NF-KB-like Transcription (2003) (1)
The Low Leukocyte (LLC) Mouse, a Second Model of “Senescence -Accelerated” Amyloidosis Associated with Apolipoprotein All Pro5→GLN; Prevalence of this Substitution Among Inbred Strains of Mice (1991) (1)
Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression (2017) (1)
Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes (2022) (1)
From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis. (2014) (1)
Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort (2017) (1)
Transgenic Tomatoes Expressing the 6 F Peptide and Ezetimibe Prevent Diet-induced Increases of Interferon-b and Cholesterol 25-hydroxylase in Jejunum (2017) (1)
Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease (2018) (1)
Systemic Oxidative Stress Ambient Particulate Pollutants in the Ultrafine Range Promote Early (2008) (0)
Genetic variation in high density lipoproteins (HDL) and susceptibility to atherosclerosis in the mouse (1985) (0)
ErythematosusMouse Model of Systemic Lupus lpr/lpr and Coronary Vasculitis in the MRL-Genetic Determinants of Autoimmune Disease (1998) (0)
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease (2021) (0)
Abstract 662: Assessing the Biological Consistency in Atherosclerosis Susceptibility Genes Between Mouse and Human Genetic Studies (2016) (0)
Effects of 5‐lipoxygenase deficiency on adiposity, adrenal and beta cell functions, and bone density (2006) (0)
Systems genetics applications in metabolism research (2019) (0)
Past Successes of Genetic Findings Familial Hypercholesterolemia and Low-Density Lipoprotein Cholesterol Lowering (2015) (0)
P1844The transcription factor MAFF regulates an atherosclerosis relevant gene network (2018) (0)
Ambient ultrafine PM chemicals enhance expression of genes related to vascular inflammation (2011) (0)
Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS (2018) (0)
Placental genomics mediates genetic associations with complex health traits and disease (2022) (0)
Genetic Factors Contributing to Atherosclerosis: From Humans to Mice and Back Again (1995) (0)
Abstract 1443: Systems-Based Analysis of HDL Metabolism in a Mouse Intercross between Strains CAST and C57BL6/J (CxB) (2008) (0)
The Response To Physical Activity In Mouse And Man: An Interplay Between Genetics And Exercise (2021) (0)
Abstract 625: Targeting of Heparin Binding EGF-like Growth Factor (HBEGF) Suppresses Hyperlipidemia and Atherosclerosis in LDL Receptor Deficient Mice (2016) (0)
Tu-P7: 156 Regulation of connexin 37 by oxidized phospholipids in atherosclerosis (2006) (0)
Abstract 468: Cross-species Comparison of Genetic Networks of Coronary Artery Disease (2018) (0)
The glucokinase locus is an important contributor to glucose variation in the Chinese population at high risk for type II diabetes (1994) (0)
Network‐based identification of critical transcription regulators in the metabolic syndrome in mice (2008) (0)
Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes (2022) (0)
Abstract 233: Isoproterenol-induced Cardiac Hypertrophy And Failure In Mice: Gene Network Modeling (2013) (0)
Mammary ductal epithelium controls cold-induced adipocyte thermogenesis (2022) (0)
Advisory Board and Contents (2020) (0)
Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (0)
Abstract 324: Identification of Regulators of Cardiac DNA Methylation Using a Systems Genetics Approach in Mice (2017) (0)
Intestinal cell type-specific communication networks underlie homeostasis and response to Western diet (2023) (0)
Abstract 517: Diesel Exhaust Induces Gut Dysbiosis Along With Reduced Fecal Acetate Levels And Altered Lipid Metabolism (2022) (0)
Vitamins at the heart of heart disease? (2001) (0)
Linkage of blood pressure to a locus on chromosome 4 in dutch dyslipidemic famiilies (2000) (0)
Sex-specific Associations in the Hybrid Mouse Diversity Panel help define genetic architecture (2023) (0)
In memoriam: Judith A. Berliner, Ph.D. (2022) (0)
Abstract 384: Integration of Aorta Network Models from Mouse Ath-HMDP with Human GWAS Reveals Novel Mechanisms of Coronary Artery Disease (2016) (0)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (0)
Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (0)
Localization of mouse peroxisome proliferator-activated receptor γ on Chromosome 6 (1996) (0)
JLR 2015/064352 Revision #1 Tomatoes expressing the 6F Peptide Ameliorate the Increase in Oxidized Phospholipids in the Jejunum of Mice Fed Unsaturated Lysophosphatidylcholine or Western Diet (2015) (0)
calcification (dystrophic cardiac calcinosis) in mice loci for myocardial cell necrosis and Dyscalc New (2016) (0)
for a gene-by-environment interaction. 2 (2016) (0)
Abstract 136: Host Genotype-shaped Gut Microbiome Modulate Atherosclerosis Development in Mice (2019) (0)
Xia Yang Association Studies of Vascular Diseases Use of Functional Genomics to Identify Candidate Genes Underlying Human Genetic (2012) (0)
52 HIGH-DENSITY LIPOPROTEIN MODULATES OXIDIZED PHOSPHOLIPID SIGNALING IN ENDOTHELIAL CELLS FROM PROINFLAMMATORY TO ANTI-INFLAMMATORY. (2007) (0)
Abstract 232: A Genome-wide Association of Murine Echocardiographic Measures Implicates Muscle A-type Lamin-interacting Protein (MLIP) in Isoproterenol-induced Interventricular Septal Hypertrophy (2013) (0)
A gene‐controlling response of bone marrow progenitor cells to granulocyte‐macrophage colony stimulating factors (1985) (0)
Abstract 133: A Systems Genetics Approach to Identify Genetic Pathways and Key Drivers of Isoproterenol-induced Cardiac Hypertrophy and Cardiomyopathy in Mice (2016) (0)
Abstract 351: Mechano-sensitive Ppap2b Regulates Endothelial Responses to Athero-relevant Hemodynamic Forces (2015) (0)
Author response: The genetic architecture of NAFLD among inbred strains of mice (2015) (0)
Abstract 17037: CTCF Regulates Fetal Genes and is Inversely Correlated with Cardiac Muscle Size Across 100 Mouse Strains (2014) (0)
Quantitative Trait Locus Mapping of Human Blood Pressure to a Genetic Region at or near the Lipoprotein Lipase Gene Locus on Chromosome 8 p 22 (2013) (0)
Gut bacteria impact host uric acid burden and its association with atherosclerosis (2022) (0)
Abstract 18346: Transcriptional Characterization of Glo1 Knockdown and Transgenic Mouse Models Implies a Role in Cardiometabolic Diseases (2015) (0)
Works Title A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci (0)
Sex‐Specific Genetic Regulation of Adipose Mitochondria and Their Relationship to Metabolic Syndrome (2021) (0)
Intergenerational genomic DNA methylation patterns in mouse hybrid strains (2014) (0)
A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure (2018) (0)
In Memoriam: Roger A. Davis (1945–2008) (2008) (0)
Abstract 205: Mlip is a New Integrator of Physiological Stress Required For Proper Cardiac Adaptation (2015) (0)
Abstract 346: Glucose Inhibits Cardiomyocyte Maturation Through Nucleotide Biosynthesis (2017) (0)
Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model (2018) (0)
Differential sensitivity of endothelial cells to the effects of MM-LDL (1990) (0)
Abstract 386: Identification of Genetic Regulatory Networks for Insulin Resistance in Multiple Populations of Diverse Ethnicities (2017) (0)
Decoding the cardiac regulatory LncRNAs in male and female mice using integrative genomic analysis (2022) (0)
Expressed in Lung and Other Tissues During Glucocorticoid-Attenuated Response Gene-and Lipopolysaccharide-Inducible γ an IFN-Chemoattractant ) Is α ( IFN-Inducible T Cell The Murine Chemokine CXCL 11 (2000) (0)
Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model (2020) (0)
Apolipoprotein A-I / C 4 WA-IV gene cluster in familial combined hyperlipidemia : effects on LDL-cholesterol and apolipoproteins B and CIll (2002) (0)
Abstract 1444: Weighted Gene Co-expression Network Analysis of Adipose and Liver Reveals Gene Modules Related to Plasma HDL Levels and Containing Candidate Genes at Loci Identified in Genome Wide Association Studies (2008) (0)
Abstract 16: Genomewide Association Study of Isoproterenol-Induced Heart Failure in a Large Mouse Panel (2012) (0)
Tribute to Dr. Steve Schwartz (2020) (0)
Abstract 163: Genetic Basis of Isoproterenol-Induced Cardiac Fibrosis (2014) (0)
Coagulation factor with potential for the treatment of heart failure (2022) (0)
Serum amyloid A levels are associated with coronary artery disease: the Cedars-Sinai family study (1994) (0)
residues in activation of unfolded protein response up-regulation by oxidized phospholipids: critical role of oxidized sn-2 ATF4-dependent transcription is a key mechanism in VEGF (2013) (0)
Metabolic syndrome as a modifier of atherosclerosis in murine models. (2007) (0)
Abstract 19722: Exome Sequencing Identifies a ZBTB17 Truncation Variant in Arrhythmogenic Cardiomyopathy (2017) (0)
Genetic influences on dietary fat-induced changes in low density lipoprotein subclass phenotypes (1999) (0)
Epigenome-wide association in adipose tissue from the METSIM cohort identifies novel loci and the involvement of adipocytes and macrophages in diabetes traits (2017) (0)
Abstract MP144: Identification of Epigenetic Regulators of Cardiac Hypertrophy by an Epigenome-wide Association Study in Mice (2020) (0)
Abstract 372: Master Transcriptional Regulators of Cardiac Gene Expression in Heart Failure (2018) (0)
Abstract 19686: Cardioprotective Role of Paraoxonases in Heart Failure (2014) (0)
Use of recombinant adenovirus to facilitate gene delivery into human vascular cells in vitro (1994) (0)
Abstract 18835: Chromatin Gene Cohorts, Not Individual Cardiac Genes, Modulate Cardiac Phenotype in a Genetically Diverse Population (2015) (0)
Abstract 529: High-dimensional Genetic Analysis of Lipoprotein Composition and Size in the Mouse (2015) (0)
Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure (2019) (0)
Abstract 134: Reciprocal Cardiac Chromatin Regulation by Ctcf and Hmgb2 (2015) (0)
Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico (2021) (0)
Title: Omnigenic epistasis regulates complex trait heritability (2022) (0)
Abstract 11747: The TMAO Generating Enzyme Flavin Monooxygenase 3 (FMO3) is a Novel Regulator of Cholesterol Balance (2014) (0)
Nutrient Sensing , Nutrition , and Metabolism Hamp 1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice (2017) (0)
446 A NOVEL TARGET IN THE TREATMENT OF OBESITY AND NONALCOHOLIC FATTY LIVER DISEASE: PITUITARY ADENYLATE CYCLASEACTIVATING POLYPEPTIDE (2020) (0)
2008 George L. Duff Memorial Lecture—Cardiovascular Disease: From Genetics to Systems Biology (2008) (0)
Abstract 19687: High-Density Lipoprotein Leads to Stimulation of Endothelial Protein Kinase C-β2 and Inhibition of eNOS-Activating Pathways in Patients with Coronary Disease: Role of Paraoxonase-1 Inactivation (2010) (0)
Title: Discovery and Characterization of Human Exonic Transcriptional Regulatory Elements Discovery and Characterization of Human Exonic Transcriptional Regulatory Elements Table of Contents (2012) (0)
Human PON2 S311C polymorphism impairs airway epithelia 3OC12‐HSL inactivation and alters PON2 glycosylation (2009) (0)
Abstract 65: Flavin Monoxygenase 3 (FMO3) is a Novel Regulator of Hepatic Cholesterol Metabolism and Transintestinal Cholesterol Efflux (TICE). (2013) (0)
Th-P15:117 Hyplip2, a new locus involved in lipid and glucose metabolism (2006) (0)
Kinase Promotes in Both Mice and Humans in a Sex-Specific Manner. (2020) (0)
Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application (2015) (0)
ATHEROSCLEROSIS: A NEW CANDIDATE HYPLIP2 (2007) (0)
Cross-TissueRegulatory G eneNetworks in Coronary Artery Disease Graphical Abstract Highlights (2016) (0)
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function (2022) (0)
Mo-P6:383 Fine mapping a region on chromosome 11P for familial combined hyperlipidemia (2006) (0)
Abstract 18760: Interactions Between Dietary Fiber and Gut Microbiota Modulate the Development of Atherosclerosis (2016) (0)
Abstract 222: SCARA5 and Suprabasin are Hub Genes of Co-expression Network Modules Associated with Peripheral Vein Graft Patency (2015) (0)
Integration ofMulti-omics Data fromMouseDiversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease Graphical (2018) (0)
Abstract 314: Nrf2 Expression Enhances Atherosclerotic Lesion Formation (2007) (0)
Abstract 358: Targeting of Heparin Binding EGF-like Growth Factor (HB-EGF) Efficiently Inhibits Atherosclerosis (2015) (0)
Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD. (2023) (0)
Erratum: Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids (2008) (0)
223-LB: Dissecting the BPA-Induced Disruptions in Liver–Gut Microbiota Interactions and Metabolic Health (2020) (0)
Subject Index Vol. 64, 1993 (1993) (0)
12. GENOME-WIDE GENETIC CONTROL OF FETAL PLACENTAL GENOMICS INFORMS THE DEVELOPMENT OF HEALTH, DISEASE, AND NEUROPSYCHIATRIC DISORDERS (2021) (0)
The distribution of genes for different pathways in the gene coexpression network modules (2011) (0)
Abstract 346: Genome-wide Bisulfite Sequencing After Isoproterenol Identifies DNA Methylation Modules Influencing Heart Failure Susceptibility (2013) (0)
Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut (2023) (0)
Brief UltraRapid Communication ABCC6 Localizes to the Mitochondria-Associated Membrane (2012) (0)
genes in mice Tissue-specific expression and regulation of sexually dimorphic data (2006) (0)
diet-induced atherosclerosis Genetic loci determining bone density in mice with (2013) (0)
Ongoing Promises and Public Expectations of the HGP (0)
Abstract 19809: Heparin Binding EGF-Like Growth Factor (HB-EGF) is a Novel Regulator for Hyperlipidemia (2016) (0)
Evidence for linkage of the apolipoprotein AII locus to plasma apolipoprotein AII and free fatty acid levels in mice and humans ( atherosclerosis / sib pair / animal models / complex genetic traits ) (2005) (0)
A combinatorial genetic approach identifies a significant locus that controls elevated heart rate in mice (2012) (0)
Sparse factor model for gene co-expression networks (2012) (0)
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice (2021) (0)
SWACSM Abstract Genetic drivers of cardiac remodeling in health and disease in female mice (2021) (0)
human endothelin-1 targeted to the endothelium Vascular gene expression in mice overexpressing (2015) (0)
Summary of Vascular Cell and HDL Effects of Oxidized Phospholipids (2013) (0)
Additional File 1 : Single Edge Simulations for Evaluating the NEO software (2008) (0)
Corrigendum to “Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels” [Genomics 86 (2005) 505–517] (2009) (0)
Fine mapping of the human familial combined hyperlipidemia locus on chromosome 1q21-q23 using conserved synteny to the mouse locus on chromosome 3 (2000) (0)
Abstract 5519: High Resolution Genetic Mapping Strategies for Metabolic Disease in Mice: Towards Association Based Studies (2008) (0)
We-P11:135 5-lipoxygenase: Pleiotropic effects on atherosclerosis, obesity and insulin resistance (2006) (0)
Title Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities Permalink (0)
Title Page / Contents / Preface (1989) (0)
The Ca 2 + transient as a feedback 1 sensor controlling cardiomyocyte 2 ionic conductances in mouse 3 populations (2018) (0)
Quantitative trait locus mapping of lipoprotein disorders, obesity and atherosclerosis (1994) (0)
Mutations in Human PON1: Role in Organophosphorus Sensitivity and Vascular Disease (2000) (0)
An integrative systems genetic analysis of mammalian lipid metabolism (2019) (0)
Membrane Bound O-Acyltransferase 7 (MBOAT7)-Driven Lysophosphatidylinositol (LPI) Acylation in Adipocytes Contributes to Systemic Glucose Homeostasis (2022) (0)
Profiling in Lamin Mutated Dilated Cardiomyopathy Mouse Model Using RNA Sequence Analysis (2016) (0)
Abstract 18178: Cardiotonic Steroid Lactone Ring Hydrolysis by Paraoxonases Attenuates Na/K ATPase Mediated Signaling (2015) (0)
1173-P: Sex Differences in NASH Pathways Informed by Multiomics (2021) (0)
Relationship between genetic variation in thermal stability and electrophoretic mobility of mouse β-galactosidase (1978) (0)
The Genetic Architecture of Tetrachloride-Induced Liver Fibrosis in Mice. (2020) (0)
MouseApolipoprotein A-IVGene:Nucleotide Sequence and Induction byaHigh-Lipid Diet (1986) (0)
Mouse Chromosome 8 (2004) (0)
Abstract 17401: Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia and Liver Steatosis (2018) (0)
Inheritance in mice of the membrane anchor protein egasyn: The Eg locus determines egasyn levels (1977) (0)
Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal Chromosome 1 by linkage analysis (1997) (0)
Contribution of Regulatory-Gene Networks to Heritability of Coronary Artery Disease (2019) (0)
APOLIPOPROTEIN B (APO B) GENE IN CONGENITAL DISORDERS OF FAT ABSORPTION (1989) (0)
University of California, Los Angeles Receives $500,000 Bristol-Myers Squibb Unrestricted Cardiovascular Research Grant (2004) (0)
Referees for Volume 41 (2004) (0)
Accelerated Gluconeogenesis in a Familial Combined Hyperlipidemia (FCHL) Mouse Model: A Glucose Metabolome Study (2002) (0)
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity (2020) (0)
DIFFERENTIAL REGULATION OF HUMAN BILE ACID BINDER (HBAB) GENE EXPRESSION BY CHOLESTASIS IN TRANSGENIC MICE: 45 (1997) (0)
Abstract: 1018 SYSTEMS GENETICS APPROACH TO METABOLIC SYNDROME (2009) (0)
Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (0)
Genetic, dietary, and sex-specific regulation of hepatic ceramides and relationship between hepatic ceramides and insulin resistance (2018) (0)
Abstract 4906: Systemic Nrf2 Expression Enhances Atherosclerosis Partially by Effects on Plasma Lipoproteins (2009) (0)
Abstract 253: NOTCH1 Protects Against Atherosclerosis by Repressing Endothelial Activation and Recruitment of Inflammatory Cells (2014) (0)
Mo-W13:1 Integrating genetic and gene expression data for cardiovascular disease (2006) (0)
Genetic Regulation of Lipoprotein Lipase (1983) (0)
Chromatin Profiling in Mice Livers Reveals Unique Chromatin Variations Induced by High Fat Diet * (2014) (0)
1 Genetic and environmental control of host-gut microbiota interactions 1 (2015) (0)
Isolation and Sequencing of the RatCoq7Gene and the Mapping of MouseCoq7to Chromosome 7: Volume330,Number 2 (1996), pages 285–289 (1996) (0)
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice (2020) (0)
Chromatin variation associated with liver metabolism is mediated by transposable elements (2016) (0)
CHAPTER 3 – Genomic Approaches to Complex Disease (2009) (0)
P4471The 4q32.1 coronary artery disease locus influences disease risk via differential transcription factor binding (2017) (0)
Abstract 17113: Dietary Supplementation of Hyodeoxycholic Acid and D-Limonene Decreased Atherosclerotic Lesion Formation in LDLR Knockout Mouse (2011) (0)
Abstract MP203: Decoding The Cardiac Regulatory Long Noncoding RNAs In Male And Female Mice Using Integrative Multiomics Analysis (2021) (0)
Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA (colony-stimulating factor 1/multiple transcripts/expression library) (2016) (0)
Characterization of 5LO transgenic mouse model for atherosclerosis, adipocity, and diabetes related traits (2006) (0)
Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL 8 HDLC GWAS Locus Cannon (0)
Advisory Board and Contents (2020) (0)
Leukocyte NADPH oxidase but not myeloperoxidase regulates pancreatic trypsin activation in cerulein induced pancreatitis (2000) (0)
Hamp 1 mRNA and plasma hepcidin levels are influenced by sex and 1 strain but don ’ t predict tissue iron levels in inbred mice 2 3 (2017) (0)
Growth factors. (1980) (0)
Potential role of lipid phosphate phosphatase (LPP3) in atherosclerosis (2015) (0)
Abstract 128: Network-based Approaches to Identify Novel Regulators of Heart Failure (2015) (0)
Multi-omics approaches to disease (2017) (0)
Author response: The Ca2+ transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations (2018) (0)
Human Leukemia Cell Line K 562 Responds 300 Blood (2005) (0)
Genetics of complex diseases: from mouse to man and back (1995) (0)
Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse Chromosomes 11 and 15 respectively (1997) (0)
The TMAO-Generating En zyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance Graphical (2015) (0)
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells (2018) (0)
Processing mutants of enzymes. Abstr. (1978) (0)
XX sex chromosome complement promotes atherosclerosis in mice (2019) (0)
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS (2018) (0)
Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development (2017) (0)
The immune system is not essential for the development of aortic atherosclerotic plaques in mice fed an atherogenic diet (1994) (0)

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