Alejandra Bravo
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Mexican biochemist; co-recipient of the 2010 L'Oréal-UNESCO Awards for Women in Science
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Alejandra Bravobiology Degrees
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Biology
Alejandra Bravo's Degrees
- Bachelors Biochemistry National Autonomous University of Mexico
- Masters Biochemistry National Autonomous University of Mexico
- PhD Biochemistry National Autonomous University of Mexico
Why Is Alejandra Bravo Influential?
(Suggest an Edit or Addition)According to Wikipedia, María Alejandra Bravo de la Parra is a Mexican biochemist who was laureated with the 2010 L'Oréal-UNESCO Award for Women in Science – Latin America for her work on a bacterial toxin that acts as a powerful insecticide. Bravo has co-authored multiple papers with her husband Mario Soberon.
Alejandra Bravo's Published Works
Published Works
- Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. (2007) (1166)
- Bacillus thuringiensis: A story of a successful bioinsecticide. (2011) (882)
- RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. (2011) (688)
- How Bacillus thuringiensis has evolved specific toxins to colonize the insect world. (2001) (660)
- Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection. (2013) (575)
- Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. (2003) (421)
- Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains. (2004) (420)
- Characterization of cry Genes in a Mexican Bacillus thuringiensis Strain Collection (1998) (411)
- How to cope with insect resistance to Bt toxins? (2008) (253)
- Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells? (2009) (251)
- Cadherin‐like receptor binding facilitates proteolytic cleavage of helix α‐1 in domain I and oligomer pre‐pore formation of Bacillus thuringiensis Cry1Ab toxin (2002) (251)
- Engineering Modified Bt Toxins to Counter Insect Resistance (2007) (247)
- Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. (2005) (220)
- Evolution of Bacillus thuringiensis Cry toxins insecticidal activity (2013) (213)
- Specific PCR primers directed to identify cryI and cryIII genes within a Bacillus thuringiensis strain collection (1995) (196)
- Diversity of Bacillus thuringiensis Strains from Latin America with Insecticidal Activity against Different Mosquito Species (2003) (168)
- Heliothis virescens and Manduca sextaLipid Rafts Are Involved in Cry1A Toxin Binding to the Midgut Epithelium and Subsequent Pore Formation* (2002) (165)
- Role of Alkaline Phosphatase from Manduca sexta in the Mechanism of Action of Bacillus thuringiensis Cry1Ab Toxin* (2010) (158)
- A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae. (2006) (155)
- PCR analysis of the cryI insecticidal crystal family genes from Bacillus thuringiensis (1994) (149)
- Phylogenetic relationships of Bacillus thuringiensis delta-endotoxin family proteins and their functional domains (1997) (146)
- 6.6 – Bacillus thuringiensis: Mechanisms and Use (2005) (145)
- Single Amino Acid Mutations in the Cadherin Receptor from Heliothis virescens Affect Its Toxin Binding Ability to Cry1A Toxins* (2005) (140)
- Immunocytochemical localization of Bacillus thuringiensis insecticidal crystal proteins in intoxicated insects (1992) (140)
- Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance (2011) (133)
- Interactions of Bacillus thuringiensis crystal proteins with the midgut epithelial cells of Spodoptera frugiperda (Lepidoptera: Noctuidae). (1996) (133)
- Role of receptor interaction in the mode of action of insecticidal Cry and Cyt toxins produced by Bacillus thuringiensis (2007) (128)
- Domain II Loop 3 of Bacillus thuringiensis Cry1Ab Toxin Is Involved in a “Ping Pong” Binding Mechanism with Manduca sexta Aminopeptidase-N and Cadherin Receptors* (2009) (126)
- Strategies to improve the insecticidal activity of Cry toxins from Bacillus thuringiensis (2009) (119)
- Immunocytochemical analysis of specific binding of Bacillus thuringiensis insecticidal crystal proteins to lepidopteran and coleopteran mudgut membranes (1992) (116)
- δ‐Endotoxins induce cation channels in Spodoptera frugiperda brush border membranes in suspension and in planar lipid bilayers (1995) (115)
- Molecular basis for Bacillus thuringiensis Cry1Ab toxin specificity: two structural determinants in the Manduca sexta Bt-R1 receptor interact with loops alpha-8 and 2 in domain II of Cy1Ab toxin. (2003) (110)
- Mapping the Epitope in Cadherin-like Receptors Involved inBacillus thuringiensis Cry1A Toxin Interaction Using Phage Display* (2001) (107)
- The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis. (2010) (96)
- Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre‐pore oligomeric structure (2007) (96)
- Specific Epitopes of Domains II and III of Bacillus thuringiensis Cry1Ab Toxin Involved in the Sequential Interaction with Cadherin and Aminopeptidase-N Receptors in Manduca sexta* (2006) (93)
- Bacillus thuringiensis Cry1A toxins are versatile proteins with multiple modes of action: two distinct pre-pores are involved in toxicity (2014) (92)
- Cyt toxins produced by Bacillus thuringiensis: A protein fold conserved in several pathogenic microorganisms (2013) (90)
- Structural changes of the Cry1Ac oligomeric pre-pore from bacillus thuringiensis induced by N-acetylgalactosamine facilitates toxin membrane insertion. (2006) (89)
- Genetic Variability of Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) Populations from Latin America Is Associated with Variations in Susceptibility to Bacillus thuringiensis Cry Toxins (2006) (87)
- Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis. (2009) (85)
- Evidence of Field-Evolved Resistance of Spodoptera frugiperda to Bt Corn Expressing Cry1F in Brazil That Is Still Sensitive to Modified Bt Toxins (2015) (83)
- Processing of Cry1Ab delta-endotoxin from Bacillus thuringiensis by Manduca sexta and Spodoptera frugiperda midgut proteases: role in protoxin activation and toxin inactivation. (2001) (81)
- Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation (2009) (80)
- Pore formation by Cry toxins. (2010) (79)
- Analysis of cryIAa expression in sigE and sigK mutants of Bacillus thuringiensis (1996) (78)
- Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop α‐8 of domain II (2005) (76)
- Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism (2011) (76)
- Role of MAPK p38 in the cellular responses to pore-forming toxins (2011) (75)
- Hydropathic Complementarity Determines Interaction of Epitope 869HITDTNNK876 in Manduca sexta Bt-R1 Receptor with Loop 2 of Domain II ofBacillus thuringiensis Cry1A Toxins* (2002) (74)
- Role of toxin activation on binding and pore formation activity of the Bacillus thuringiensis Cry3 toxins in membranes of Leptinotarsa decemlineata (Say). (2004) (74)
- An alpha-amylase is a novel receptor for Bacillus thuringiensis ssp. israelensis Cry4Ba and Cry11Aa toxins in the malaria vector mosquito Anopheles albimanus (Diptera: Culicidae). (2010) (72)
- Ammonium assimilation in Rhizobium phaseoli by the glutamine synthetase-glutamate synthase pathway (1988) (71)
- A Bacillus thuringiensis S-Layer Protein Involved in Toxicity against Epilachna varivestis (Coleoptera: Coccinellidae) (2006) (69)
- Mode of action of mosquitocidal Bacillus thuringiensis toxins. (2007) (68)
- N-terminal Activation Is an Essential Early Step in the Mechanism of Action of the Bacillus thuringiensis Cry1Ac Insecticidal Toxin* (2002) (65)
- Aminopeptidase dependent pore formation of Bacillus thuringiensis CrylAc toxin on Trichoplusia ni membranes (1997) (63)
- Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate. (2004) (62)
- Multiple receptors as targets of Cry toxins in mosquitoes. (2011) (61)
- Efficacy of Genetically Modified Bt Toxins Alone and in Combinations Against Pink Bollworm Resistant to Cry1Ac and Cry2Ab (2013) (61)
- Differential Role of Manduca sexta Aminopeptidase-N and Alkaline Phosphatase in the Mode of Action of Cry1Aa, Cry1Ab, and Cry1Ac Toxins from Bacillus thuringiensis (2013) (59)
- Bacillus thuringiensis Cry1Ab Mutants Affecting Oligomer Formation Are Non-toxic to Manduca sexta Larvae* (2007) (59)
- Cadherin, Alkaline Phosphatase, and Aminopeptidase N as Receptors of Cry11Ba Toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti (2010) (57)
- Unfolding Events in the Water-soluble Monomeric Cry1Ab Toxin during Transition to Oligomeric Pre-pore and Membrane-inserted Pore Channel* (2004) (57)
- Dual mode of action of Bt proteins: protoxin efficacy against resistant insects (2015) (57)
- An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor. (2007) (57)
- Susceptibility of Four Tropical Lepidopteran Maize Pests to Bacillus thuringiensis CryI-Type Insecticidal Toxins (1997) (53)
- Mode of action of Bacillus thuringiensis PS86Q3 strain in hymenopteran forest pests. (2001) (53)
- Comparative Proteomic Analysis of Aedes aegypti Larval Midgut after Intoxication with Cry11Aa Toxin from Bacillus thuringiensis (2012) (53)
- Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity (2009) (46)
- Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus. (2010) (46)
- Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects. (2009) (46)
- ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth (2017) (45)
- Midgut GPI-anchored proteins with alkaline phosphatase activity from the cotton boll weevil (Anthonomus grandis) are putative receptors for the Cry1B protein of Bacillus thuringiensis. (2010) (44)
- The amino- and carboxyl-terminal fragments of the Bacillus thuringensis Cyt1Aa toxin have differential roles in toxin oligomerization and pore formation. (2011) (41)
- The oligomeric state of Bacillus thuringiensis Cry toxins in solution. (1999) (41)
- Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. (2009) (41)
- Resistance to Bacillus thuringiensis Mediated by an ABC Transporter Mutation Increases Susceptibility to Toxins from Other Bacteria in an Invasive Insect (2016) (40)
- Structural and functional studies of α-helix 5 region from Bacillus thuringiensis Cry1Ab δ-endotoxin (2001) (38)
- Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin. (2000) (38)
- Identification of ABCC2 as a binding protein of Cry1Ac on brush border membrane vesicles from Helicoverpa armigera by an improved pull‐down assay (2016) (37)
- Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action (2017) (37)
- Isolation of Cry1Ab protein mutants of Bacillus thuringiensis by a highly efficient PCR site-directed mutagenesis system. (1996) (35)
- Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae. (2013) (35)
- Aedes aegypti alkaline phosphatase ALP1 is a functional receptor of Bacillus thuringiensis Cry4Ba and Cry11Aa toxins. (2012) (34)
- Evaluation of the Impact of Genetically Modified Cotton After 20 Years of Cultivation in Mexico (2018) (34)
- The pre-pore from Bacillus thuringiensis Cry1Ab toxin is necessary to induce insect death in Manduca sexta (2008) (33)
- A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis (2007) (32)
- Cadherin binding is not a limiting step for Bacillus thuringiensis subsp. israelensis Cry4Ba toxicity to Aedes aegypti larvae. (2012) (31)
- Identification of distinct K+ channels in mouse spermatogenic cells and sperm (2002) (30)
- Pore formation activity of Cry1Ab toxin from Bacillus thuringiensis in an improved membrane vesicle preparation from Manduca sexta midgut cell microvilli. (2002) (30)
- Genetic Basis of Cry1F-Resistance in a Laboratory Selected Asian Corn Borer Strain and Its Cross-Resistance to Other Bacillus thuringiensis Toxins (2016) (29)
- Assessment of cry1 Gene Contents of Bacillus thuringiensis Strains by Use of DNA Microarrays (2005) (29)
- Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae. (2013) (29)
- FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes. (2017) (29)
- A Single Point Mutation Resulting in Cadherin Mislocalization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm* (2017) (29)
- The investigation of air quality and acid rain over the Gulf of Mexico (1990) (28)
- A membrane associated metalloprotease cleaves Cry3Aa Bacillus thuringiensis toxin reducing pore formation in Colorado potato beetle brush border membrane vesicles. (2007) (28)
- Role of Tryptophan Residues in Toxicity of Cry1Ab Toxin from Bacillus thuringiensis (2006) (28)
- Analysis of the change in atmospheric urban formaldehyde and photochemistry activity as a result of using methyl-t-butyl-ether (MTBE) as an additive in gasolines of the metropolitan area of Mexico city (1991) (27)
- Mode of Action of Cry Toxins from Bacillus thuringiensis and Resistance Mechanisms (2016) (27)
- Bt resistance: characterization and strategies for GM crops producing Bacillus thuringiensis toxins. (2015) (27)
- A Tenebrio molitor GPI-anchored alkaline phosphatase is involved in binding of Bacillus thuringiensis Cry3Aa to brush border membrane vesicles (2013) (26)
- Structural and functional analysis of the pre-pore and membrane-inserted pore of Cry1Ab toxin. (2006) (26)
- Characterization of the Cry1Ah resistance in Asian corn Borer and its cross-resistance to other Bacillus thuringiensis toxins (2018) (26)
- Toxicity of Cry1A toxins from Bacillus thuringiensis to CF1 cells does not involve activation of adenylate cyclase/PKA signaling pathway. (2017) (25)
- Characterization of novel Brazilian Bacillus thuringiensis strains active against Spodoptera frugiperda and other insect pests (2004) (25)
- The CRISPR-Cas systems were selectively inactivated during evolution of Bacillus cereus group for adaptation to diverse environments (2020) (25)
- The C-terminal protoxin region of Bacillus thuringiensis Cry1Ab toxin has a functional role in binding to GPI-anchored receptors in the insect midgut (2018) (25)
- Isolated domain II and III from the Bacillus thuringiensis CrylAb δ‐endotoxin binds to lepidopteran midgut membranes (1997) (25)
- Cry64Ba and Cry64Ca, Two ETX/MTX2-Type Bacillus thuringiensis Insecticidal Proteins Active against Hemipteran Pests (2017) (25)
- Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity (2018) (25)
- Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis (2015) (24)
- Toxicity of Bacillus thuringiensis delta-endotoxins against bean shoot borer (Epinotia aporema Wals.) larvae, a major soybean pest in Argentina. (2007) (24)
- A single amino acid polymorphism in ABCC2 loop 1 is responsible for differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species. (2018) (24)
- Modified Bacillus thuringiensis Toxins and a Hybrid B. thuringiensis Strain Counter Greenhouse-Selected Resistance in Trichoplusia ni (2009) (23)
- The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host (2021) (22)
- Genetic analysis of cryIIIA gene expression in Bacillus thuringiensis. (1996) (22)
- Defense and death responses to pore forming toxins (2009) (22)
- Cryptic endotoxic nature of Bacillus thuringiensis Cry1Ab insecticidal crystal protein (2004) (21)
- Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins (2011) (21)
- Oligomerization of Cry11Aa from Bacillus thuringiensis Has an Important Role in Toxicity against Aedes aegypti (2009) (21)
- Two ABC transporters are differentially involved in the toxicity of two Bacillus thuringiensis Cry1 toxins to the invasive crop-pest Spodoptera frugiperda (J. E. Smith). (2020) (21)
- Domains II and III of Bacillus thuringiensis Cry1Ab Toxin Remain Exposed to the Solvent after Insertion of Part of Domain I into the Membrane* (2011) (21)
- Synergistic activity of Bacillus thuringiensis toxins against Simulium spp. larvae. (2014) (21)
- Bacterial Toxins Active against Mosquitoes: Mode of Action and Resistance (2021) (21)
- Roles of insect midgut cadherin in Bt intoxication and resistance. (2015) (20)
- Introduction of the Escherichia coli gdhA gene into Rhizobium phaseoli: effect on nitrogen fixation (1988) (20)
- Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis (2013) (20)
- Cry toxin binding site models and their use in strategies to delay resistance evolution. (2015) (20)
- Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis) (2018) (20)
- Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage. (2006) (19)
- Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm (2015) (19)
- Isolation and characterization of a Saccharomyces cerevisiae mutant with impaired glutamate synthase activity (1989) (18)
- Corrigendum to “The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis” [Insect Biochem. Mol. Biol. 40 (1) (2010) 58–63] (2013) (18)
- The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin (2019) (18)
- Insect resistance management and integrated pest management for Bt crops: Prospects for an area-wide view (2015) (17)
- Assembling of Holotrichia parallela (dark black chafer) midgut tissue transcriptome and identification of midgut proteins that bind to Cry8Ea toxin from Bacillus thuringiensis (2015) (16)
- Toxicity and mode of action of insecticidal Cry1A proteins from Bacillus thuringiensis in an insect cell line, CF-1 (2014) (16)
- Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins (2008) (15)
- Tobacco plants expressing the Cry1AbMod toxin suppress tolerance to Cry1Ab toxin of Manduca sexta cadherin-silenced larvae. (2011) (15)
- Use of Bacillus thuringiensis Toxin as an Alternative Method of Control against Haemonchus contortus (2006) (15)
- Encapsulation Strategies for Bacillus thuringiensis: From Now to the Future. (2021) (15)
- Membrane binding and oligomer membrane insertion are necessary but insufficient for Bacillus thuringiensis Cyt1Aa toxicity (2014) (14)
- Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests (2015) (14)
- Identification of midgut membrane proteins from different instars of Helicoverpa armigera (Lepidoptera: Noctuidae) that bind to Cry1Ac toxin (2018) (13)
- The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda (2020) (13)
- Cell lines as models for the study of Cry toxins from Bacillus thuringiensis. (2018) (13)
- Comprehensive analysis of Cry1Ac protoxin activation mediated by midgut proteases in susceptible and resistant Plutella xylostella (L.). (2020) (13)
- A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth (2022) (12)
- Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta (2017) (12)
- Insecticidal Specificity of Cry1Ah to Helicoverpa armigera Is Determined by Binding of APN1 via Domain II Loops 2 and 3 (2016) (12)
- The potential impact of gasoline additives on air quality in developing countries (2006) (11)
- Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa Toxicity to Spodoptera frugiperda by Domain III Mutations Indicates There Are Two Limiting Steps in Toxicity as Defined by Receptor Binding and Protein Stability (2018) (11)
- Synergistic resistance of Helicoverpa armigera to Bt toxins linked to cadherin and ABC transporters mutations. (2021) (11)
- Transgenic cotton co-expressing chimeric Vip3AcAa and Cry1Ac confers effective protection against Cry1Ac-resistant cotton bollworm (2017) (10)
- Reduced Expression of a Novel Midgut Trypsin Gene Involved in Protoxin Activation Correlates with Cry1Ac Resistance in a Laboratory-Selected Strain of Plutella xylostella (L.) (2020) (10)
- Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans (2018) (10)
- Identification of an alkaline phosphatase as a putative Cry1Ac binding protein in Ostrinia furnacalis (Guenée). (2016) (9)
- Chemical Fingerprinting, Isolation and Characterization of Polyphenol Compounds from Heliotropium taltalense (Phil.) I.M. Johnst and Its Endothelium-Dependent Vascular Relaxation Effect in Rat Aorta (2020) (9)
- Identification of Cry1Ah-binding proteins through pull down and gene expression analysis in Cry1Ah-resistant and susceptible strains of Ostrinia furnacalis. (2020) (9)
- Spodoptera frugiperda (J. E. Smith) Aminopeptidase N1 Is a Functional Receptor of the Bacillus thuringiensis Cry1Ca Toxin (2018) (9)
- Structural and functional studies of alpha-helix 5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin. (2001) (9)
- Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12. (2015) (9)
- GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility. (2019) (9)
- Helix α-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family (2018) (9)
- Bacillus thuringiensis Cry1AbMod toxin counters tolerance associated with low cadherin expression but not that associated with low alkaline phosphatase expression in Manduca sexta (2015) (9)
- MAPK-mediated transcription factor GATAd contributes to Cry1Ac resistance in diamondback moth by reducing PxmALP expression (2022) (8)
- Adoption of Bacillus thuringiensis-based biopesticides in agricultural systems and new approaches to improve their use in Brazil (2021) (8)
- Holotrichia oblita Midgut Proteins That Bind to Bacillus thuringiensis Cry8-Like Toxin and Assembly of the H. oblita Midgut Tissue Transcriptome (2017) (8)
- Variability of Bacillus thuringiensis Strains by ERIC-PCR and Biofilm Formation (2014) (8)
- Insect Hsp90 Chaperone Assists Bacillus thuringiensis Cry Toxicity by Enhancing Protoxin Binding to the Receptor and by Protecting Protoxin from Gut Protease Degradation (2019) (8)
- Oligomerization is a key step for Bacillus thuringiensis Cyt1Aa insecticidal activity but not for toxicity against red blood cells. (2020) (8)
- Resistance management for Bt maize and above-ground lepidopteran targets in the USA: from single gene to pyramided traits. (2015) (8)
- CHAPTER 8:Towards a Healthy Control of Insect Pests: Potential Use of Microbial Insecticides (2011) (8)
- Nitric oxide participates in the toxicity of Bacillus thuringiensis Cry1Ab toxin to kill Manduca sexta larvae (2015) (7)
- An Intramolecular Salt Bridge in Bacillus thuringiensis Cry4Ba Toxin Is Involved in the Stability of Helix α-3, Which Is Needed for Oligomerization and Insecticidal Activity (2017) (7)
- In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti (2021) (7)
- Susceptible and mCry3A resistant corn rootworm larvae killed by a non-hemolytic Bacillus thuringiensis Cyt1Aa mutant (2018) (7)
- Resistance of Busseola fusca to Cry1Ab Bt maize plants in South Africa and challenges to insect resistance management in Africa. (2015) (6)
- Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field (2012) (6)
- Design of an aqueous two-phase system for the purification of ICP from Bacillus thuringiensis (1994) (6)
- SfABCC2 transporter extracellular loops 2 and 4 are responsible for the Cry1Fa insecticidal specificity against Spodoptera frugiperda. (2021) (6)
- Functional Bacillus thuringiensis Cyt1Aa Is Necessary To Synergize Lysinibacillus sphaericus Binary Toxin (Bin) against Bin-Resistant and -Refractory Mosquito Species (2020) (6)
- New Insights into the Mode of Action of Cry1Ab Toxin used in Transgenic Insect-Resistant Crops (2010) (6)
- Systematic characterization of Bacillus Genetic Stock Center Bacillus thuringiensis strains using Multi-Locus Sequence Typing. (2018) (5)
- Bacillus thuringiensis cry toxin triggers autophagy activity that may enhance cell death. (2020) (5)
- The ω‐endotoxin protein family displays a hydrophobic motif that might be implicated in toxicity (1992) (5)
- Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes (2015) (5)
- Nutrient conditions determine the localization of Bacillus thuringiensis Vip3Aa protein in the mother cell compartment (2020) (5)
- Identification of Bacillus thuringiensis Cry1AbMod binding-proteins from Spodoptera frugiperda (2017) (5)
- Efficiency of insecticidal crystal protein production in a Bacillus thuringiensis mutant with derepressed expression of the terminal oxidase aa3 during sporulation (1993) (5)
- Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta (2020) (5)
- Efficient Production of Bacillus thuringiensis Cry1AMod Toxins under Regulation of cry3Aa Promoter and Single Cysteine Mutations in the Protoxin Region (2013) (5)
- 125. Cadherin Binding Is Not a Limiting Step for Bacillus thuringiensis subs. israelensis Cry4Ba Toxicity to Aedes aegypti Larvae (2012) (4)
- Induction of Manducasexta Larvae Caspases Expression in Midgut Cells by Bacillusthuringiensis Cry1Ab Toxin (2011) (4)
- The Cyt1Aa toxin from Bacillus thuringiensis inserts into target membranes via different mechanisms in insects, red blood cells, and lipid liposomes (2020) (4)
- Bacillus thuringiensis Cry1Ac Protoxin and Activated Toxin Exert Differential Toxicity Due to a Synergistic Interplay of Cadherin with ABCC Transporters in the Cotton Bollworm (2022) (4)
- Role of GPI-Anchored Membrane Receptors in the Mode of Action of Bacillus thuringiensis Cry Toxins (2012) (4)
- RNA interference strategy for crop protection against insect pests. (2015) (4)
- Status of resistance to Bt cotton in China: cotton bollworm and pink bollworm. (2015) (3)
- Whole Genome Sequencing Analysis of Bacillus thuringiensis GR007 Reveals Multiple Pesticidal Protein Genes (2021) (3)
- Coexistence of cry9 with the vip3A Gene in an Identical Plasmid of Bacillus thuringiensis Indicates Their Synergistic Insecticidal Toxicity. (2020) (3)
- Identification of a Bacillus thuringiensis Surface Layer Protein with Cytotoxic Activity against MDA-MB-231 Breast Cancer Cells. (2017) (3)
- Induction of Manduca sexta Larvae Caspases Expression in Midgut Cells by Bacillus thuringiensis Cry 1 Ab Toxin (2014) (3)
- Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore-forming toxins to Caenorhabditis elegans. (2020) (3)
- Bt toxin not guilty by association (2005) (3)
- Erratum: Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae (Journal of Biological Chemistry (2007) 282 (21222-21229) DOI:10.1074/jbc.A113.701314) (2013) (3)
- Different models of the mode of action of Bt 3d-Cry toxins. (2015) (2)
- Mechanism of Cry1Ac resistance in cabbage loopers - a resistance mechanism selected in insect populations in an agricultural environment. (2015) (2)
- Biodiversity of Cry toxins produced by Bacillus thuringiensis and evolution of resistance to these toxins in different insect pests (2018) (2)
- Cyt1Aa from Bacillus thuringiensis subsp. israelensis synergizes Cry11Aa toxin activity by functioning as a membrane-bound receptor. (2005) (2)
- Rapid spread of a densovirus in a major crop pest following wide-scale adoption of Bt-cotton in China (2021) (2)
- Degradation of Cry1Ac protoxin can explain the decreased susceptibility in late instars of Helicoverpa armigera. (2018) (2)
- Oligomerization of Cry9Aa in solution without receptor binding, is not related with insecticidal activity (2016) (2)
- Bacillus thuringiensis Cry1Ab Domain III β-16 Is Involved in Binding to Prohibitin, Which Correlates with Toxicity against Helicoverpa armigera (Lepidoptera: Noctuidae) (2020) (2)
- [Microorganisms in the biological control of insects and phytopathogens]. (2006) (2)
- Characterization of Two Novel Bacillus thuringiensis Cry8 Toxins Reveal Differential Specificity of Protoxins or Activated Toxins against Chrysomeloidea Coleopteran Superfamily (2020) (2)
- Mitochondrial markers to distinguish Spodoptera frugiperda populations associated with corn and cotton crops (2016) (2)
- Avoiding Insect Resistance to Cry Toxins from Bacillus thuringiensis (2008) (2)
- A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness (2022) (2)
- The role of proteolysis in the biological activity of Bt insecticidal crystal proteins. (2015) (2)
- A major conformational change of N-terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for membrane insertion and toxicity. (2022) (1)
- NOTES Introduction oftheEscherichia coli gdhAGeneintoRhizobium phaseoli: Effect on Nitrogen Fixation (1988) (1)
- Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis (2015) (1)
- Strategies to Reduce Insecticide Use in Agricultural Production (2015) (1)
- Bacillus thuringiensis Cry1Ab Domain III β-22 Mutants with Enhanced Toxicity to Spodoptera frugiperda (J. E. Smith) (2020) (1)
- Resistance of cabbage loopers to Btk in a greenhouse setting: occurrence, spread and management. (2015) (1)
- Erratum for the Report: "Engineering modified Bt toxins to counter insect resistance" (Science (2007) (1640-1642)) (2014) (1)
- Molecular Cloning, Expression, and Identification of Bre Genes Involved in Glycosphingolipids Synthesis in Helicoverpa armigera (Lepidoptera: Noctuidae) (2016) (1)
- Identification of scFv molecules that recognize loop 3 of domain II and domain III of CryIAb toxin from Bacillus thuringiensis. (2005) (1)
- Rapid spread of a symbiotic virus in a major crop pest following wide-scale adoption of Bt-cotton in China (2021) (1)
- Using DNA microarrays for assessing crystal protein genes in Bacillus thuringiensis. (2007) (0)
- Insect chaperones Hsp70 and Hsp90 cooperatively enhance toxicity of Bacillus thuringiensis Cry1A toxins and counteract insect resistance (2023) (0)
- Addendum: Bedoya-Pérez, L.P. et al. Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis. Int. J. Mol. Sci. 2013, 14, 8467–8478 (2016) (0)
- Structural changes upon membrane insertion of the insecticidal pore-forming toxins produced by Bacillus thuringiensis (2023) (0)
- Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity (2018) (0)
- New Bacillus thuringiensis strains and pesticide composition containing (1995) (0)
- jmbReview Identification of a Bacillus thuringiensis Surface Layer Protein with Cytotoxic Activity against MDA-MB-231 Breast Cancer Cells (2017) (0)
- Oligomerization of Cry11Aa from Bacillus thuringiensis Has an Important Role in Toxicity against Aedes aegypti (2013) (0)
- Important Interactions with Membrane Receptors in the Mode of Action of Bacillus thuringiensis Cry Toxins (2005) (0)
- Susceptible and mCry3A resistant corn rootworm larvae killed by a non-hemolytic Bacillus thuringiensis Cyt1Aa mutant (2018) (0)
- Transgenic cotton co-expressing chimeric Vip3AcAa and Cry1Ac confers effective protection against Cry1Ac-resistant cotton bollworm (2017) (0)
- Is aminopeptidase N the receptor of CryIAc delta-endotoxin in Trichoplusia ni midgut? (1998) (0)
- Correction: Dominant Negative Mutants of Bacillus thuringiensis Cry1Ab Toxin Function as Anti-Toxins: Demonstration of the Role of Oligomerization in Toxicity (2013) (0)
- The lessons that Caenorhabditis elegans has taught us about the mechanism of action of crystal proteins. (2015) (0)
- Domains II and III of Bacillus thuringiensis Cry1Ab toxin remain exposed to the solvent after insertion of part of domain I into the membrane. (2012) (0)
- fixation.Rhizobium phaseoli: effect on nitrogen Introduction of the Escherichia coli gdhA gene (2013) (0)
- A Colorado potato beetle membrane associated metalloprotease is involved in the mode of action of Cry 3 Aa Bacillus thuringiensis toxin (0)
- Erratum to: Permeability Changes of Manduca sexta Midgut Brush Border Membranes Induced by Oligomeric Structures of Different Cry Toxins (2012) (0)
- Identification and characterization of ion transporters in plants (2010) (0)
- Aedes aegypti innate immune response after Bacillus thuringiensis Cry11Aa exposure. (2012) (0)
- Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes (2015) (0)
- Characterization of the Cry1Ah resistance in Asian corn Borer and its cross-resistance to other Bacillus thuringiensis toxins (2018) (0)
- Characterization by PCR analysis of cryl genes from Bacillus Thuringiensis strains efficient against fall armyworm, Spodoptera frugiperda. (1997) (0)
- Helix α-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family (2018) (0)
- Countering pest resistance with genetically modified Bt toxins. (2015) (0)
- The delta-endotoxin protein family displays a hydrophobic motif that might be implicated in toxicity. (1992) (0)
- A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth (2022) (0)
- ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth (2017) (0)
- Variability of Bacillus thuringiensis Strains by ERIC-PCR and Biofilm Formation (2014) (0)
- Functional studies of helix alpha-5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin (2003) (0)
- The development and prospect of discovery of Bt toxin genes. (2015) (0)
- Author response: Rapid spread of a densovirus in a major crop pest following wide-scale adoption of Bt-cotton in China (2021) (0)
- Cysteine Mutations in the Protoxin Region Promoter and Single cry3Aa Regulation of thuringiensis Cry1AMod Toxins under Efficient Production of Bacillus (2013) (0)
- Proteínas insecticidas de bacillus thuringiensis (2001) (0)
- Bacillus thuringiensis Cry 1 Ab Toxin from Role of Tryptophan Residues in Toxicity of (2005) (0)
- Oligomer formation of different Cry toxins indicates that a pre-pore is an essential intermediate in the mode of action of the three-domain Cry family. (2007) (0)
- Association between chronic periodontitis and herpes viruses: A review of the literature. (2020) (0)
- CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-5-GERANYL-BENZOIC ACID (2016) (0)
- Mode of Action of Bacillus thuringiensis-Genetically Modified Cry1AbMod and Cry1AcMod Toxins: Role of Alkaline pH in Toxin Oligomerization (2010) (0)
- Mining versus in vitro evolution for the selection of novel microbial insecticidal proteins (2022) (0)
- Assembling of Holotrichia parallela (dark black chafer) midgut tissue transcriptome and identification of midgut proteins that bind to Cry8Ea toxin from Bacillus thuringiensis (2015) (0)
- Erratum for the Report: “Engineering Modified Bt Toxins to Counter Insect Resistance” by M. Soberón, L. Pardo-López, I. López, I. Gómez, B. E. Tabashnik, A. Bravo (2014) (0)
- Rearrangement of N-Terminal α-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity (2020) (0)
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