Aleksandra Walczak
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Biophysicist
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Aleksandra Walczakphysics Degrees
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Physics
Aleksandra Walczak's Degrees
- Bachelors Physics University of Warsaw
- Masters Biophysics University of Warsaw
- PhD Biophysics University of California, Berkeley
Why Is Aleksandra Walczak Influential?
(Suggest an Edit or Addition)According to Wikipedia, Aleksandra M. Walczak is a theoretical biophysicist. She works on stochastic gene expression at Ecole Normale Supérieure where she is a research director. Education Walczak completed her master's degree at Warsaw University, Poland in 2002, her PhD at University of California, San Diego in 2007, and was a post-doc until 2010 at Princeton University.
Aleksandra Walczak's Published Works
Published Works
- Statistical mechanics for natural flocks of birds (2011) (548)
- Maximum entropy models for antibody diversity (2009) (291)
- Self-regulating gene: an exact solution. (2005) (248)
- Statistical inference of the generation probability of T-cell receptors from sequence repertoires (2012) (238)
- Predicting evolution (2017) (205)
- Information transmission in genetic regulatory networks: a review (2011) (163)
- High-throughput immune repertoire analysis with IGoR (2018) (159)
- Social interactions dominate speed control in poising natural flocks near criticality (2013) (154)
- Inferring processes underlying B-cell repertoire diversity (2015) (152)
- The Past, Present, and Future of Immune Repertoire Biology – The Rise of Next-Generation Repertoire Analysis (2013) (150)
- Live Imaging of Bicoid-Dependent Transcription in Drosophila Embryos (2013) (148)
- Optimizing information flow in small genetic networks. (2009) (134)
- Absolute rate theories of epigenetic stability. (2005) (129)
- Quantifying selection in immune receptor repertoires (2014) (122)
- OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs (2018) (113)
- Flocking and Turning: a New Model for Self-organized Collective Motion (2014) (106)
- Optimizing information flow in small genetic networks. II. Feed-forward interactions. (2009) (103)
- Self-consistent proteomic field theory of stochastic gene switches. (2004) (102)
- Genetic Diversity and the Structure of Genealogies in Rapidly Adapting Populations (2012) (100)
- How a well-adapted immune system is organized (2014) (98)
- Genetic Diversity in the Interference Selection Limit (2014) (87)
- A Reassessment of IgM Memory Subsets in Humans (2015) (86)
- Abduction and asylum in the lives of transcription factors (2010) (83)
- Precise tracking of vaccine-responding T cell clones reveals convergent and personalized response in identical twins (2018) (82)
- Predicting the spectrum of TCR repertoire sharing with a data‐driven model of recombination (2018) (82)
- Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves (2016) (80)
- Diversity of immune strategies explained by adaptation to pathogen statistics (2015) (75)
- Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires (2016) (74)
- Spectral solutions to stochastic models of gene expression with bursts and regulation. (2009) (72)
- Local equilibrium in bird flocks (2015) (72)
- The Energy Landscapes of Repeat-Containing Proteins: Topology, Cooperativity, and the Folding Funnels of One-Dimensional Architectures (2008) (68)
- Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection (2020) (66)
- Fluctuating fitness shapes the clone-size distribution of immune repertoires (2015) (65)
- Quantifying lymphocyte receptor diversity (2016) (63)
- A stochastic spectral analysis of transcriptional regulatory cascades (2008) (62)
- Dynamical maximum entropy approach to flocking. (2013) (61)
- Signal Percolation within a Bacterial Community. (2018) (60)
- Detecting T cell receptors involved in immune responses from single repertoire snapshots (2019) (53)
- Method for identification of condition-associated public antigen receptor sequences (2017) (52)
- Analytic methods for modeling stochastic regulatory networks. (2010) (51)
- The Structure of Genealogies in the Presence of Purifying Selection: A Fitness-Class Coalescent (2010) (49)
- Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in lung cancer (2021) (46)
- Genesis of the αβ T-cell receptor (2018) (45)
- Optimizing information flow in small genetic networks. III. A self-interacting gene. (2012) (44)
- Exotic quantum phases and phase transitions in correlated matter (2005) (43)
- Precision of Readout at the hunchback Gene: Analyzing Short Transcription Time Traces in Living Fly Embryos (2016) (40)
- Transcriptional Memory in the Drosophila Embryo (2016) (38)
- How many different clonotypes do immune repertoires contain? (2019) (37)
- repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data (2015) (35)
- Single molecule microscopy reveals key physical features of repair foci in living cells (2020) (35)
- Constructing explicit magnetic analogies for the dynamics of glass forming liquids. (2008) (32)
- Detecting T-cell receptors involved in immune responses from single repertoire snapshots (2018) (32)
- Fierce Selection and Interference in B-Cell Repertoire Response to Chronic HIV-1 (2018) (32)
- How a well-adapting immune system remembers (2018) (31)
- Langevin dynamics of proteins at constant pH. (2002) (30)
- Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones (2020) (30)
- Extinction and resurrection in gene networks (2008) (30)
- 3 minutes to precisely measure morphogen concentration (2018) (30)
- Epistasis in a Fitness Landscape Defined by Antibody-Antigen Binding Free Energy. (2019) (29)
- Combinatorial code governing cellular responses to complex stimuli (2015) (29)
- New methods to image transcription in living fly embryos: the insights so far, and the prospects (2016) (28)
- Disorder and the Neural Representation of Complex Odors (2017) (27)
- Neoantigen quality predicts immunoediting in survivors of pancreatic cancer (2022) (27)
- Precision in a rush: Trade-offs between reproducibility and steepness of the hunchback expression pattern (2018) (27)
- Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection (2021) (26)
- Deep generative selection models of T and B cell receptor repertoires with soNNia (2020) (26)
- Quantitative Immunology for Physicists (2019) (26)
- Noise Expands the Response Range of the Bacillus subtilis Competence Circuit (2015) (25)
- Insights into immune system development and function from mouse T-cell repertoires (2017) (25)
- Influence of decoys on the noise and dynamics of gene expression. (2012) (24)
- Transitions in optimal adaptive strategies for populations in fluctuating environments. (2017) (23)
- Capturing coevolutionary signals inrepeat proteins (2014) (22)
- Population variability in the generation and selection of T-cell repertoires (2020) (21)
- Information-optimal transcriptional response to oscillatory driving. (2010) (21)
- Building General Langevin Models from Discrete Datasets (2019) (20)
- RBM-MHC: A Semi-Supervised Machine-Learning Method for Sample-Specific Prediction of Antigen Presentation by HLA-I Alleles (2020) (18)
- A mechanism for hunchback promoters to readout morphogenetic positional information in less than a minute (2020) (18)
- IGoR: a tool for high-throughput immune repertoire analysis (2017) (18)
- Population variability in the generation and thymic selection of T-cell repertoires (2020) (18)
- Effect of phenotypic selection on stochastic gene expression. (2013) (18)
- Inferring the immune response from repertoire sequencing (2019) (18)
- Repeat proteins challenge the concept of structural domains. (2015) (18)
- Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies (2020) (17)
- Transition path sampling algorithm for discrete many-body systems. (2012) (17)
- Physical epistatic landscape of antibody binding affinity (2017) (15)
- Time-dependent information transmission in a model regulatory circuit. (2013) (15)
- Learning the heterogeneous hypermutation landscape of immunoglobulins from high-throughput repertoire data (2020) (15)
- Trade-Offs in Delayed Information Transmission in Biochemical Networks (2015) (14)
- Antigenic waves of virus–immune coevolution (2021) (14)
- Roadmap on biology in time varying environments (2021) (13)
- The structure of allelic diversity in the presence of purifying selection. (2010) (13)
- Rényi entropy, abundance distribution, and the equivalence of ensembles. (2016) (12)
- Population dynamics of immune repertoires (2017) (12)
- Size and structure of the sequence space of repeat proteins (2019) (12)
- Immune fingerprinting through repertoire similarity (2020) (11)
- Cost and benefits of clustered regularly interspaced short palindromic repeats spacer acquisition (2019) (11)
- Origin of Public Memory B Cell Clones in Fish After Antiviral Vaccination (2018) (11)
- Variable habitat conditions drive species covariation in the human microbiota (2017) (11)
- Multi-Lineage Evolution in Viral Populations Driven by Host Immune Systems (2019) (10)
- Active degradation of MarA controls coordination of its downstream targets (2018) (10)
- Physical observables to determine the nature of membrane-less cellular sub-compartments (2021) (10)
- Gene-gene cooperativity in small networks. (2008) (10)
- Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies (2021) (9)
- Extending the dynamic range of transcription factor action by translational regulation. (2015) (8)
- Affinity maturation for an optimal balance between long-term immune coverage and short-term resource constraints (2021) (8)
- Benchmarking solutions to the T-cell receptor epitope prediction problem: IMMREP22 workshop report (2022) (7)
- Repertoire sequencing and the statistical ensemble approach to adaptive immunity (2017) (7)
- Physical constraints in biological collective behaviour (2018) (7)
- Inferring repeat-protein energetics from evolutionary information (2017) (6)
- Generative models of T-cell receptor sequences. (2020) (6)
- Interference limits resolution of selection pressures from linked neutral diversity (2013) (6)
- Evidence for Shaping of Light Chain Repertoire by Structural Selection (2018) (5)
- Probing T-cell response by sequence-based probabilistic modeling (2020) (5)
- Live Imaging of mRNA Transcription in Drosophila Embryos. (2018) (5)
- LiveFly: A Toolbox for the Analysis of Transcription Dynamics in Live Drosophila Embryos. (2018) (5)
- hunchback Promoters Can Readout Morphogenetic Positional Information in Less Than a Minute (2019) (5)
- Optimal prediction with resource constraints using the information bottleneck (2020) (4)
- On generative models of T-cell receptor sequences (2019) (4)
- Flocking and Turning: a New Model for Self-organized Collective Motion (2014) (4)
- What Can Immunologists Learn from Systems Approaches? (2018) (4)
- Progress and open problems in evolutionary dynamics. (2018) (4)
- From evolution to folding of repeat proteins (2022) (3)
- Flexible machine learning prediction of antigen presentation for rare and common HLA-I alleles (2020) (3)
- Learning the statistics and landscape of somatic mutation-induced insertions and deletions in antibodies (2021) (3)
- SOS: online probability estimation and generation of T-and B-cell receptors (2020) (3)
- Constraints and limitations on the transcriptional response downstream of the Bicoid morphogen gradient. (2020) (3)
- Clonal competition in B-cell repertoires during chronic HIV-1 infection (2018) (3)
- Dissipation in Non-Steady State Regulatory Circuits (2019) (3)
- NoisET: Noise Learning and Expansion Detection of T-Cell Receptors. (2021) (3)
- Precision of readout at the hunchback gene (2016) (2)
- Evolution and folding of repeat proteins (2022) (2)
- Inferring the T-cells repertoire dynamics of healthy individuals (2022) (2)
- Comprehensive analysis of antiviral adaptive immunity formation and reactivation down to single-cell level (2019) (2)
- A model for the integration of conflicting exogenous and endogenous signals by dendritic cells (2016) (2)
- Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription (2022) (2)
- Signatures of irreversibility in microscopic models of flocking. (2022) (2)
- Cooperation of multiple copies of noisy genes (2008) (2)
- Probabilities of HIV-1 bNAb development in healthy and chronically infected individuals (2022) (1)
- Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals (2021) (1)
- Population based selection shapes the T cell receptor repertoire during thymic development (2022) (1)
- Quantifying changes in the T cell receptor repertoire during thymic development (2023) (1)
- Questioning the activity of active matter in natural flocks of birds (2015) (1)
- Cost and benefits of CRISPR spacer acquisition (2018) (1)
- Immune fingerprinting (2020) (1)
- Learning the differences: a transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity (2022) (1)
- Inspecting the interaction between human immunodeficiency virus and the immune system through genetic turnover (2023) (1)
- Constraints and limitations on the transcriptional response downstream of the Bicoid morphogen gradient (2019) (1)
- The Structure of Genealogies in the Presence of Purifying Selection: An Effective Coalescent Theory (2010) (1)
- Habitat Fluctuations Drive Species Covariation in the Human Microbiota (2015) (1)
- Combining mutation and recombination statistics to infer clonal families in antibody repertoires (2022) (1)
- Precise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins (2018) (1)
- Many body theory of stochastic gene expression (2007) (0)
- DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age (2022) (0)
- High-throughput immune repertoire analysis with IGoR (2018) (0)
- Author response: Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones (2020) (0)
- Questioning the activity of active matter: the case of bird flocks (2016) (0)
- Optimal strategies for timekeeping in cells (2010) (0)
- Live Imaging of Bicoid-Depe (2013) (0)
- Capturing coevolutionary signals in repeat proteins Capturing coevolutionary signals in repeat proteins (2014) (0)
- Design Principles of an Optimal Adaptive Immune System (2014) (0)
- Signal transmission in a heterogeneous bacterial population (2018) (0)
- Inspecting the interaction between HIV and the immune system through genetic turnover (2022) (0)
- Antigenic waves of virus-immune co-evolution (2021) (0)
- Response in Immune Repertoires (2021) (0)
- Cost and Precision in Small Gene Regulatory Networks (2015) (0)
- High-Throughput Ig Sequencing of Paired Blood and Spleen Samples Allows a Redefinition of Memory IgM Subsets in Humans (2014) (0)
- Dynamical information synergy in biochemical signaling networks (2023) (0)
- MINIMALIST: Mutual INformatIon Maximization for Amortized Likelihood Inference from Sampled Trajectories (2021) (0)
- Effect of random environments on clone size distributions of the immune repertoire (2014) (0)
- Method for identification of 1 condition-associated public antigen 2 receptor sequences (0)
- Correction for Sethna et al., Insights into immune system development and function from mouse T-cell repertoires (2017) (0)
- What are the current driving questions in immune repertoire research? (2022) (0)
- Information processing in small gene regulatory networks and cascades (2010) (0)
- Capturing coevolutionary signals inrepeat proteins (2015) (0)
- Renormalization group approach to connect discrete- and continuous-time descriptions of Gaussian processes. (2021) (0)
- Evolutionary stability of antigenically escaping viruses (2023) (0)
- Telling time with an intrinsically noisy clock (2010) (0)
- Active degradation of a regulator controls coordination of downstream genes (2018) (0)
- Humansof IgM Memory Subsets in (2015) (0)
- Fluctuating fitness shapes the clone size distribution of immune repertoires (2015) (0)
- Modeling antigen presentation and immune recognition with Restricted Boltzmann Machines (2021) (0)
- Statistical investigations into immune system diversity in mice and man (0)
- Tiling solutions for optimal biological sensing (2015) (0)
- Mouse T cell repertoires as statistical ensembles: overall characterization and age dependence (2016) (0)
- Properties of gene expression including the non-functional binding of transcription factors to DNA (2012) (0)
- Granger causality analysis for calcium transients in neuronal networks, challenges and improvements (2023) (0)
- Affinity maturation for an optimal balance between long-term immune coverage and short-term resource constraints (2022) (0)
- Organization of an optimal adaptive immune system (2017) (0)
- Synthetic deconstruction of hunchback regulation by Bicoid (2021) (0)
- The Connection between Discrete- and Continuous-Time Descriptions of Gaussian Continuous Processes (2021) (0)
- Repertoire-based approach to identifying sequence motifs specific to an effective vaccine (2018) (0)
- Towards a quantitative theory of tolerance (2023) (0)
- Neoantigen quality predicts immunoediting in survivors of pancreatic cancer (2022) (0)
- Author response: Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection (2020) (0)
- Statistical Models of Adaptive Immune populations (2016) (0)
- Noise Induced Biological Adaptation Differs between Analogous Differentiation Circuits (2011) (0)
- Interdisciplinary approaches to predicting evolutionary biology (2023) (0)
- Trade-Offs in Delayed Information Transmission in Biochemical Networks (2015) (0)
- Electrical Signal Transmission in a Heterogeneous Population of Bacteria (2018) (0)
- PE ] 8 N ov 2 01 8 Cost and benefits of CRISPR spacer acquisition (2018) (0)
- Predicting the future from the past in visual object motion: optimal representations of mixed stochastic/deterministic trajectories (2020) (0)
- Diversity of immune systems. (2017) (0)
- [Evolutionary explanation of the diversity of immune strategies]. (2017) (0)
- Constraints and limitations on decoding positional information: the Bicoid case-study (2019) (0)
- Generalized Glauber dynamics for inference in biology (2022) (0)
- Author response: A mechanism for hunchback promoters to readout morphogenetic positional information in less than a minute (2019) (0)
- Flexible gene pools (2015) (0)
- Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in non-small cell lung cancer patients (2020) (0)
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